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HASE Sumihiro  長谷 純宏

ORCIDConnect your ORCID iD *help
Researcher Number 80028232
External Links
Affiliation (based on the past Project Information) *help 2004 – 2005: 大阪大学, 大学院・理学研究科, 教授
1998 – 2000: 大阪大学, 大学院・理学研究科, 教授
1997 – 1998: 大阪大学, 大学院理学研究科, 教授
1989 – 1995: 大阪大学, 理学部, 教授
1988: Osaka University College of Science, Associate Prof., 理学部, 助教授
1987: 大阪大学, 理学部, 講師
Review Section/Research Field
Principal Investigator
物質生物化学 / Structural biochemistry / Functional biochemistry / Structural biochemistry
Except Principal Investigator
物質生物化学 / Structural biochemistry
Keywords
Principal Investigator
糖鎖 / HPLC / ピリジルアミノ化 / 糖蛋白質 / 蛍光標識 / オリゴ糖 / 酵素 / 脳 / ピリジルアミノ化法 / 人工複合糖質 … More / 2次元マップ / Sugar chain / Fluorescence labeling / マンノシダ-ゼ / 基質特異性 / マンノシダーゼ / ニワトリ / Glycoprotein / Pyridylamination / ウズラ / 輸卵管 / コバルト / 逆相 / ピリジアルアミノ化 / マウス / 二次元マップ / ゼブラフィッシュ / ルイスX / O^ー配糖体 / ヒドラジレ分解 / Oー配糖体 / ヒドラジン分解 / O-Sugar chain / Hydrazinolysis / キシロシルグルコース / キシロ-ス / 尿 / 肝臓 / 少糖 / Xylosylglucose / コバルトイオン / ピリジルアミニ化法 / mannosidase / sugar chain / cobalt / hen / pyridylamination / ビリジルアシノ化 / 部分水解 / 構造 / ピソジルアミノ化 / 2D-map / Pyridylaminotion / oligosaccharide / partial acid hydrolysis / Sturcfure / 糖タンパク質 / Fluorescent labeling / Glycoproteins / 2-Dimensiona map / 糖組成分析 / Component sugar analysis … More
Except Principal Investigator
細胞移動 / 糖タンパク質 / 糖脂質 / 糖転移酵素 / 血液凝固VII因子 / 血液凝固IX因子 / 外因系凝固反応 / プロテインZ / 糖ペプチド / キシロ-ズ / グルコ-ス / 上皮細胞増殖成長因子(EGF) / 糖鎖解析 / リ-ラ-マウス / ピリビルアミノ化 / グルコース転移酵素 / 神経芽細胞 / グルコシルセラミド / リーラマウス / N-結合型糖鎖 / 糖鎖自動分析 / HPLC / 蛍光標識 / ヒドラジン分解 / ガングリオシド / 細胞接着 / レクチン / ムチン / 糖鎖欠損 / 統鎖生物学 / プロチオグリカン / 発生分化 / 統転移酵素 / マクロファ-ジ / エンドサイト-シス / 癌転移 / ガラクト-ス転移酵素 / エンドグリコシダ-ゼ / Glycoprotein / Glycolipid / Ganglioside / Cell adhesion / Glycosyltransferase / Lectin / Mucin / Carbohydrate deficience / エンド型グリコシダーゼ / 糖転移反応 / ペプチドへの糖鎖導入 / 糖鎖の切り出し / 複合糖質 / 橋渡し部分 / 糖鎖工学 / プロテオグリカン / 糖鎖切り出し / 糖鎖組み換え / 糖鎖限定分解 / endo-type glycosidase / transglycosylation / carbohydrate transferation in to peptide / cutting out carbohydrate chain / glycoconjugate / linkage region / glycotechnology / キシロース転移酵素 / 血液凝固 / EGF様ドメイン / 糖鎖 / 糖鎖合成 / キシロシル-グルコース / 血液凝固因子 / EGFドメイン / 合成酵素 / SUGAR TRANSFERASE / XYLOSYLTRANSFERASE / BLOOD COAGULATION / EGF-LIKE DOMAIN / SUGAR CHAIN / SYNTHESIS OF SUGAR CHAIN / XYLOSYL-GLUCOSE / BLOOD COAGULATION FACTOR Less
  • Research Projects

    (23 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (27 People)
  •  神経胚中期に現れるルイスX構造の意義Principal Investigator

    • Principal Investigator
      長谷 純宏
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Structural biochemistry
    • Research Institution
      Osaka University
  •  ビリジルアミノ化法を用いた精密人工複合糖質の作成Principal Investigator

    • Principal Investigator
      長谷 純宏
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  ピリジルアミノ化法を用いた精密人工複合糖質の作成Principal Investigator

    • Principal Investigator
      長谷 純宏
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  脳特異的糖鎖BA2の生理学的意義の解明

    • Principal Investigator
      池中 一裕
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Okazaki National Research Institutes
  •  Analysis of Oligosaccharide Structures from the Reducing End Terminal by Combining Partial Acid Hydrolysis and a Two-Dimensional Sugar MapPrincipal Investigator

    • Principal Investigator
      HASE Sumihiro
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Osaka University
  •  PURIFICATION OF AN ENZYME SYNTHESIZING Z SUGAR CHAIN CHARACTERISTIC TO EGF-LIKE DOMAINS OF PROTEINS ASSOCIATED WITH BLOOD COAGULATION

    • Principal Investigator
      OMICHI Kaoru
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      OSAKA WOMEN'S UNIVERSITY
  •  ピリジルアミノ化法を用いた精密人工複合糖質の作成Principal Investigator

    • Principal Investigator
      長谷 純宏
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Developments in the new glycotechnology using the specific activity of endo-glycosidases

    • Principal Investigator
      ENDO Masahiko
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Structural biochemistry
    • Research Institution
      Hirosaki University
  •  ピリジルアミノ化法を用いた脳特異的糖鎖の構造解析と脳内分布Principal Investigator

    • Principal Investigator
      長谷 純宏
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  ピリジルアミノ化法を用いた脳特異的糖鎖の構造解析と脳内分布Principal Investigator

    • Principal Investigator
      長谷 純宏
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  ピリジルアミノ化法を用いた脳特異的糖鎖の構造解析と脳内分布Principal Investigator

    • Principal Investigator
      長谷 純宏
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  マウス大脳皮質形成における細胞外グルコース転移酵素の役割

    • Principal Investigator
      池中 一裕
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okazaki National Research Institutes
  •  Analysis of activation of neutral alpha-mannosidase activated with Co(II)Principal Investigator

    • Principal Investigator
      HASE Sumihiro
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Osaka University
  •  蛍光標識少糖による蛋白質の糖鎖構造認識の解析Principal Investigator

    • Principal Investigator
      長谷 純宏
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  New Development in glycobiology

    • Principal Investigator
      MURAMATSU Takashi
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      物質生物化学
    • Research Institution
      Nagoya University School of Medicine
      Kagoshima University
  •  Search for xylosylglucose-type sugar chains by pyridylaminationPrincipal Investigator

    • Principal Investigator
      HASE Sumihiro
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Osaka University
  •  蛍光標識少糖による蛋白質の糖鎖構造認識の解析Principal Investigator

    • Principal Investigator
      長谷 純宏
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  蛍光標識少糖による蛋白質の糖鎖構造認識の解析Principal Investigator

    • Principal Investigator
      長谷 純宏
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  血液凝固VII因子及びIX因子に発見された新しいSer結合型糖鎖の構造と機能解析

    • Principal Investigator
      岩永 貞昭
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      Kyushu University
  •  大脳皮質形成の分子機構の解明

    • Principal Investigator
      池中 一裕
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Sensitive analysis of O-linked sugar chains by fluorescence labelingPrincipal Investigator

    • Principal Investigator
      HASE Sumihiro
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Osaka University
  •  Structure analysis of glycoproteins by two dimensional HPLC mapping with high sensitivityPrincipal Investigator

    • Principal Investigator
      HASE Sumihiro
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      Osaka University
  •  Practical Application of Fluorescence Labeling to Component Sugar Analysis of GlycoproteinsPrincipal Investigator

    • Principal Investigator
      HASE Sumihiro
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      物質生物化学
    • Research Institution
      Osaka University

All 2005 2004

All Journal Article Book

  • [Book] Advances in Plant Physiology Vol.72004

    • Author(s)
      Ishimizu, T., Hase, S.
    • Publisher
      Pectin biosynthesis(in press)
    • Data Source
      KAKENHI-PROJECT-16657030
  • [Journal Article] Alteration of Brain Type N-Glycans in Neurological Mutant Mouse Brain2005

    • Author(s)
      S.Nakakita, S.Natsuka, J.Okamoto, K.Ikenaka, S.Hase
    • Journal Title

      J.Biochem. 138(3)

      Pages: 277-283

    • NAID

      10017346999

    • Data Source
      KAKENHI-PROJECT-16657030
  • [Journal Article] Changes in N-Linked Suger Chain Patterns Induced by Moderate-to-High Expression of the Galactosyltransferase I Gene in a Brain-Derived Cell Line, CG42005

    • Author(s)
      K.N.Menon, T.Ikeda, I.Fujimoto, H.Narimatsu, S.Nakakita, S.Hase, K.Ikenaka
    • Journal Title

      J.Neurosci.Res. 80(1)

      Pages: 29-36

    • Data Source
      KAKENHI-PROJECT-16657030
  • [Journal Article] Expression of Complex-type N-glycans in Developmental Periods of Zebrafisch Embryo2005

    • Author(s)
      T.Takemoto, S.Natsuka, S.Nakakita, S.Hase
    • Journal Title

      Glycoconjugate J. 22

      Pages: 20-26

    • Data Source
      KAKENHI-PROJECT-16657030
  • [Journal Article] Characterization of Wheat Germ Agglutinin Ligand on Soluble Glycoproteins in Caenorhabditis elegans2005

    • Author(s)
      S.Natsuka, M.Kawaguchi, Y.Wada, A.Ichikawa, K.Ikura, S.Hase
    • Journal Title

      J.Biochem. 138(2)

      Pages: 209-213

    • NAID

      10017346737

    • Data Source
      KAKENHI-PROJECT-16657030
  • [Journal Article] Chemical Synthesis of uridine 51-diphospho-a-D-xylopyranose Tetrahedron Asymmetry2005

    • Author(s)
      T.Ishimizu, T.Uchida, K.Sano, S.Hase
    • Journal Title

      Tetrahedron Asymmetry (in press)

    • Data Source
      KAKENHI-PROJECT-16657030
  • [Journal Article] Substrate Specificity and Molecular Cloning of Endo-β-Mannosidase Acting on N-Glycan in Lilium longiflorum2005

    • Author(s)
      A.Sasaki, T.Ishimizu, S.Hase
    • Journal Title

      J.Biochem 137(1)

      Pages: 87-93

    • Data Source
      KAKENHI-PROJECT-16657030
  • [Journal Article] Substrate Recognition by Sugar Chain-Related Enzymes : Recognition of a Large Area of Substrates and Its Stricteness and Tolerance2005

    • Author(s)
      T.Ishimizu, S.Hase
    • Journal Title

      TIGG 97(17)

      Pages: 215-227

    • NAID

      10016881981

    • Data Source
      KAKENHI-PROJECT-16657030
  • [Journal Article] Synthesis of β-mannosides Using the Transglycosylation Activity of Endo-β-mannosidase from Lilium longiflorum2005

    • Author(s)
      A.Sasaki, T.Ishimizu, R.Geyer, S.Hase
    • Journal Title

      FEBS Journal 272(7)

      Pages: 1660-1668

    • Data Source
      KAKENHI-PROJECT-16657030
  • [Journal Article] Endo-beta-mannosidase, a Plant Enzyme Acting on N-Glycan : Purification2004

    • Author(s)
      T.Ishimizu, A.Sasaki, S.I.Okutani, M.Maeda, M.Yamagishi, S.Hase
    • Journal Title

      J.Biol.Chem. 279

      Pages: 38555-38562

    • Data Source
      KAKENHI-PROJECT-16657030
  • [Journal Article] Synthesis and Conformational Characterization of the Epidermal Growth Factor-like Domain of Blood Coagulation Factor IX Carrying Xylosyl-glucose2004

    • Author(s)
      M.Kitamura, H.Hojo, Y.Nakahara, T.Ishimizu, S.Hase
    • Journal Title

      Glycoconjugate J 21

      Pages: 197-203

    • Data Source
      KAKENHI-PROJECT-16657030
  • 1.  池中 一裕 (00144527)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  ENDO Masahiko (20004616)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  MURAMATSU Takashi (00030891)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  IRIMURA Tatsuro (80092146)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  KAWASAKI Toshisuke (50025706)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  NAGAI Yoshitaka (80072974)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  SAITO Masaki (60012762)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  ITO Makoto (40253512)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  YAMAMOTO Kenji (70109049)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ITO Kazuo (20183171)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  TAKEGAWA Kaoru (50197282)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  OMICHI Kaoru (90028259)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  IKENAKA Tokuji (20028088)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  岩永 貞昭 (90029942)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  太和田 勝久 (20029507)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  御子柴 克彦 (30051840)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  藤本 一朗 (70264710)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  牧田 章 (60004561)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  鈴木 明身 (70134533)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  小川 智也 (30087572)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  瀬野 信子 (40017182)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  山科 郁男 (70025675)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  傘 育子 (00184458)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  堀田 恭子 (10050402)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  TSUKAMOTO Shigehisa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  KONDO Akihiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  KATO Ikunoshin
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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