SUGAHARA Kazuyuki 菅原一幸

Researcher Number	60154449
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2015: 北海道大学, 先端生命科学研究科, 名誉教授 2015: 北海道大学, 大学院先端生命科学研究院, 名誉教授 2014 – 2015: 北海道大学, 先端生命科学研究科(研究院), 名誉教授 2014: 北海道大学, 先端生命科学研究院, 名誉教授 2013: 北海道大学, 先端生命科学研究科(研究院), 学術研究員 … More
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / 物質生物化学 / Biological Sciences / Structural biochemistry / 医薬分子機能学 Except Principal Investigator Biological pharmacy / 物質生物化学 / Ophthalmology / 代謝生物化学 / Biological pharmacy
Keywords	Principal Investigator コンドロイチン硫酸 / プロテオグリカン / ヘパラン硫酸 / グリコサミノグリカン / デルマタン硫酸 / 硫酸化 / ヘパリン / chondroitin sulfate / 硫酸基転移酵素 / 糖転移酵素 … More Except Principal Investigator コンドロイチン硫酸 / プロテオグリカン / グリコサミノグリカン / ヘパラン硫酸 / cDNA / デルマタン硫酸 / Tn抗原 / ヒアルロニダーゼ / mRNA / ヒアルロン酸 / 単クローン抗体 / レクチン / ヒト繊維芽細胞cDNAライブラリー / ミッドカイン / 糖タンパク質 / endogenous ligand / ヒアル / ニュージーランド / バトロキソビンのアミノ酸配列 / ムチン型糖鎖 / ムチン型糖タンパク質 / NPPア-ゼの全一次構造 / 骨形成 / Htombin-like enzyme / ヒト線維芽細胞cDNAライブラリー / 三重ラセン構造 / リソソーム酵素 / NPPア-ゼのゲノムDNA / 結腸癌細胞 / Batroxobin cDNA / 癌 / 糖鎖特異的単クローン抗体 / コラーゲン構造 / スルフォトランスフェラーゼ / 組換DNA / 酵素複合体 / 肝レクチン / LOWE症候群 / バトロキソビン / Monoclonal antibody / 神経再生 / コラーゲン / 骨・皮膚疾患 / 動物レクチン / ダンロス症候群/糖転移酵素/硫酸基転移酵素 / ムチン / Lowe症候群 / Mucin-type glycoprotein / 酵素活性の昂進と転写・翻訳 / 糖尿病網膜症 / 糖鎖 / スプライシング / マンナン結合タンパク質 / コンドロイチン硫酸/デルマタン硫酸/骨 / プロテアーゼ / Low's Syndrome / 一次構造 / Animal lectin / N-グリコリルノイラミン酸 / signal peptide / アルツハイマー病 / ノーザン分析 / Carbohydrate directed monoclonal antibody / シグナル入力 / 糖鎖シグナル / serum glycoprotein / セラミド / バトロキソビンの大腸菌内発現 / Active Sulfate (PAPS) / Phosphodiesterase I / CMP-NeuAc水酸化酸素 / シアリルルイスA / ホスホジエスタラ-ゼI / シアリルLe^a抗原 / ビトロネクチン / Genomic DNA of NPPase / 結腸がん / 酵素精製 / プロテインホスファターゼ / 血清糖タンパク質 / 変形性関節症 / LS180 / がん関連抗原 / 活性硫酸 / collagen / がん抗原 / 先天性代謝異常 / 抗原糖鎖構造 / 硫酸化グルコサミノグリカン / 硫酸転移酵素 / てんかん / 異種抗原 / 血液凝固 / ムチン糖鎖 / ガン抑制遺伝子 / Rattle snake / 基質特異性 / 糖尿病 / ヒツジ顎下腺ムチン(OSM) / ドイツ / 内在性リガンド / ガラクトース転移酵素 / 蛇毒 / バトロキソビン遺伝子の構造 / Tumor-assiciated antigen / ガングリオシド / 遺伝病 / primary structure / ロー症候群 / ヌクレオチドピロホスファターゼ / ヌクレオチドピロホスファタ-ゼ(NPPア-ゼ) / SW1118 / Oーグリコシド型糖鎖 / アネキシンファミリー / N-アセチルガラクトサミニルトランスフェラーゼ / クローニング / 遺伝病における酵素活性の昂進 / Transcription and Translation Relevant to Elevation of Enzyme Activity / CMP-NeuAc水酸化酵素 / アミノ酸配列 / 加水分解酵素 / L-セレクチン / 癌関連抗原 / ラット肝cDNAライブラリー / エンドグリコセラミダーゼ / Nucleotide Pyrophosphatase (NPPase) / シグナルペプチド / 皮膚/遺伝病/脊椎骨端異形成症/ エーラス / スルホトランスフェラーゼ / トロンビン様酵素 / ガラガラ蛇 / フコシダーゼ / Batroxobin / 糖転移酵素 / 遺伝子 / ギラン・バレー症候群 / バトロキソビンcDNA / Expression of batroxobin in E. coli / Elevation of Enzyme Activity in a Genetic Disease / 老化 / Primary Structure of NPPase / シンデカン / 硫酸基転移酵素 / 糖鎖硫酸化 / 硫酸化グリコサミノグリカン / RAGE / ヌクレオチドピロホスファターゼ遺伝子 Less

Involvement of Sulfated Gycosaminoglycan in the Pathogenesis of Diabetic Retinopathy
- Principal Investigator
  
  YOSHIZAWA Chikako
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Hokkaido University
Drug discovery of innovative small molecules with inhibition of RAGE-GAG interactionPrincipal Investigator
- Principal Investigator
  
  KAZUYUKI Sugahara
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Roles of chondroitin sulfate interacting with RAGE involved in tumor and Alzheimer's disease
- Principal Investigator
  
  Shiji Mizumoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Meijo University
プロテオグリカンとコンドロイチン硫酸結合性タンパク質に関する統合的神経糖鎖生物学Principal Investigator
- Principal Investigator
  
  菅原一幸
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Structural and functional studies on the novel hyaluronidase trying for its clinical application
- Principal Investigator
  
  YAMADA Shuhei
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Meijo University
Molecular mechanism for roles of chondroitin sulfate in tumor metastasisPrincipal Investigator
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Pathogenic mechanisms of the bone diseases caused by defect in chondroitin sulfate biosynthesis
- Principal Investigator
  
  MIZUMOTO Shuji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Identification of endo-type chondroitin sulfate hydrolases applicable to neuronal regenerative therapy
- Principal Investigator
  
  YAMADA Shuhei
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Molecular mechanism of proteoglycan signalingsPrincipal Investigator
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Biosynthetic mechanism and functional analysis of sulfated glycosaminoglycans aimed at elucidating the pathology and therapy
- Principal Investigator
  
  KITAGAWA Hiroshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Pharmaceutical University
Functional analysis of glycosaminoglycans as a potential drug target and the decoding of carbohydrate signaling of the functional domainsPrincipal Investigator
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
胎児脳のグリコサミノグリカンによる神経幹細胞の分化と神経突起伸長の分子メカニズムPrincipal Investigator
- Principal Investigator
  
  菅原一幸
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
  Kobe Pharmaceutical University
Development of a fundamental technology, which is applicable to drug development and therapeutic applications through analysis of sulfated glycosaminoglycan chainsPrincipal Investigator
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  KOBE PHARMACEUTICAL UNIVERSITY
コンドロイチン/デルマタン硫酸の神経突起伸長促進機能とその分子メカニズムPrincipal Investigator
- Principal Investigator
  
  菅原一幸
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Pharmaceutical University
Scenario of the biosynthesis of glycosaminoglycansPrincipal Investigator
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
  Kobe Pharmaceutical University
Analysis of the biosynthetic mechanism and functions of glycosaminogycans by manipulating the genes encoding biosynthetic enzymes.Principal Investigator
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Pharmaceutical University
Development of the haparan sulfate-based anti-cancer drugsPrincipal Investigator
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  KOBE PHARMACEUTICAL UNIVERSITY
パートタイムプロテオグリカンへの糖鎖付加の分子スイッチの同定とその機能調節の解明Principal Investigator
- Principal Investigator
  
  菅原一幸
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Pharmaceutical University
糖鎖シグナルによる細胞間コミュニケーションの制御
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nagoya University
生理活性糖類・硫酸化グリコサミノグリカンの構造と生合成に関する研究Principal Investigator
- Principal Investigator
  
  菅原一幸
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Pharmaceutical University
神経突起伸長と血管新生におけるグリコサミノグリカン糖鎖の分子認識Principal Investigator
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Biological pharmacy
- Research Institution
  KOBE PHARMACEUTICAL UNIVERSITY
Development of a universal sequencing method for sulfated glycosaminoglycansPrincipal Investigator
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kobe Pharmaceutical University
細胞の増殖・分化促進活性を有する硫酸化グリコサミノグリカン糖鎖の分子認識Principal Investigator
- Principal Investigator
  
  菅原一幸
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  医薬分子機能学
- Research Institution
  Kobe Pharmaceutical University
Studies on the Biosynthetic Mechanism of Bioactive Sulfated GlycosaminoglycansPrincipal Investigator
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kobe Pharmaceutical University
Structure and Biosynthesis of Carbohydrate-Protein Linkage Region of Dermatan Sulfate and Chondroitin SulfatePrincipal Investigator
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kobe Pharmaceutical University
糖鎖発現の制御因子
- Principal Investigator
  
  鈴木明身
- Project Period (FY)
  1993 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
グリコサミノグリカン多糖鎖のリン酸化と硫酸化による精密硫酸化構造の意義に関する研究Principal Investigator
- Principal Investigator
  
  菅原一幸
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe Pharmaceutical University
Structural Study on th Carbohydrate-Protein Linkage Region of ProteglycansPrincipal Investigator
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Women's College of Pharmacy
Structural Studies on the Carbohydrate-Protein Linkage Region of ProteoglycansPrincipal Investigator
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Kobe Women's College of Pharmacy
がん抗原としのムチン型糖タンパク質の特性
- Principal Investigator
  
  山科郁男
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
Biosynthetic and Immunochemical Investigation of Sulfated GlycosaminoglycansPrincipal Investigator
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  KYOTO UNIVERSITY
Structure of antigenic complex carbohydrate chains recongnized by carbohydrate directed monoclonal antibodies
- Principal Investigator
  
  FUNAKOSHI Ikuo
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Kyoto University
タンパク質・糖質の硫酸化の生物学的意義および反応機作に関する生化学的研究Principal Investigator
- Principal Investigator
  
  菅原一幸
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Kyoto University
Biochemical studies of Lowe's syndrome
- Principal Investigator
  
  YAMASHINA Ikuo
- Project Period (FY)
  1986 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  代謝生物化学
- Research Institution
  Kyoto Sangyo University
  Kyoto University
Studies on the structure and function of the liver mannan-binding protein by utilizing gene recombinant technology.
- Principal Investigator
  
  KAWASAKI Toshisuke
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoto University
Studies on production of a thrombin-like snake venom enzyme using a recombinant DNA
- Principal Investigator
  
  YAMASHINA Ikuo
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  物質生物化学
- Research Institution
  Kyoto University

[Book] Encyclopedia of Polymeric Nanomaterials2015
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Shuhei Yamada
- Total Pages
  2500
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-25860037
[Book] グリコサミノグリカン・プロテオグリカンの分解 In 糖鎖の新機能開発・応用ハンドブック～創薬・医療からヘルスケアまで～2015
- Author(s)
  山田修平、水本秀二、菅原一幸
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-25860037
[Book] Chondroitin Sulfate In Encyclopedia of Polymeric Nanomaterials2015
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Shuhei Yamada
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25860037
[Book] Encyclopedia of Polymeric Nanomaterials2015
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, and Shuhei Yamada
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24590071
[Book] ヘパラン硫酸 In 糖鎖の新機能開発・応用ハンドブック～創薬・医療からヘルスケアまで～2015
- Author(s)
  水本秀二、菅原一幸
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-25860037
[Book] Carbohydrate (N-acetyl-D-galactosamine 4-O) sulfotransferase 14 (CHST14) In Handbook of Glycosyltransferases and Related Gene2014
- Author(s)
  Tomoki Kosho, Shuji Mizumoto, Kazuyuki Sugahara
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25860037
[Book] 「ISCSM2011 Chondroitin sulfate E-type structure at tumor cell surface is involved in experimental metastasis (Chapter 3)」, Advances in Experimental Medicine and Biology "Biochemical Roles of Eukaryotic Cell Surface Macromolecules", (P. R. Sudhakaran and A. Surolia, eds)2012
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto
- Publisher
  Springer, New York
- Data Source
  KAKENHI-PROJECT-23390016
[Book] 「Bone and Skin Disorders Caused by a Disturbance in the Bioynthesis of Chondroitin Sulfate and Dermatan Sulfate 」, Extracellular matrix : Pathobiology and signaling , (N. Karamanos ed.)2012
- Author(s)
  Shuji Mizumoto, Kazuyuki Sugahara
- Publisher
  Walter De Gruyter, Berlin, Germany
- Data Source
  KAKENHI-PROJECT-23390016
[Book] Walter De Gruyter, Berlin, Germany2012
- Author(s)
  Shuji MIZUMOTO and Kazuyuki SUGAHARA、Bone and Skin Disorders Caused by a Disturbance in the Bioynthesis of Chondroitin Sulfate and Dermatan Sulfate
- Publisher
  Extracellular matrix: Pathobiology and signaling, (N. Karamanos ed.)
- Data Source
  KAKENHI-PROJECT-23790066
[Book] Bone and Skin Disorders Caused by a Disturbance in the Bioynthesis of Chondroitin Sulfate and Dermatan Sulfate in Extracellular matrix: Pathobiology and signaling2012
- Author(s)
  Shuji MIZUMOTO and Kazuyuki SUGAHARA
- Publisher
  Walter De Gruyter, Berlin, Germany
- Data Source
  KAKENHI-PROJECT-23790066
[Book] 遺伝子医学MOOK別冊ますます重要になる細胞周辺環境(細胞ニッチ)の最新科学技術 .細胞の生存、増殖、機能のコントロールから創薬研究、再生医療まで.2009
- Author(s)
  水本秀二,山田修平,菅原一幸
- Total Pages
  230
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-21590057
[Book] Experimental Glycoscience "Glycochemistry"(Taniguchi N., Suzuki A., Ito Y., Narimatsu H., Kawasaki T., Hase S., eds) (Microsequencing of functional chondroitin sulfate oligosaccharides)2008
- Author(s)
  Sugahara K., Yamada S.
- Publisher
  Springer, Tokyo
- Data Source
  KAKENHI-PROJECT-20390019
[Book] Experimental Glycoscience Glycochemistry2008
- Author(s)
  Kazuyuki Sugahara
- Publisher
  Springer, Tokyo
- Data Source
  KAKENHI-PROJECT-20390019
[Book] Biosynthesis of Glycosaminoglycans and Proteoglycans. In Comprehensive Glycoscience (Johannis P. Kamerling, ed.)2007
- Author(s)
  Uyama, T., Kitagawa, H., and Sugahara, K.
- Publisher
  Elsevier, UK.
- Data Source
  KAKENHI-PROJECT-19390025
[Book] 未来を拓く糖鎖科学2005
- Author(s)
  菅原一幸
- Total Pages
  467
- Publisher
  金芳堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390026
[Journal Article] Molecular interactions between chondroitin-dermatan sulfate and growth factors/receptors/matrix proteins.2016
- Author(s)
  Shuji Mizumoto, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Current Opinion in Structural Biology
  
  Volume: 34 Pages: 35-42
- DOI
  10.1016/j.sbi.2015.06.004
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07951, KAKENHI-PUBLICLY-26110719, KAKENHI-PROJECT-25860037
[Journal Article] Skeletal dysplasia in a consanguineous clan from the island of Nias/Indonesia is caused by a novel mutation in B3GAT32015
- Author(s)
  Birgit S. Budde, Shuji Mizumoto, Ryo Kogawa, Christian Becker, Janine Altmuller, Holger Thiele, Franz Ruschendorf, Mohammad R. Toliat, Gerrit Kaleschke, Johannes M. Hammerle, Wolffang Hohne, Kazuyuki Sugahara, Peter Nurnberg, Ingo Kennerknecht.
- Journal Title
  
  Hum. Genet.
  
  Volume: in press Pages: 691-704
- DOI
  10.1007/s00439-015-1549-2
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670018, KAKENHI-PUBLICLY-26110719, KAKENHI-PROJECT-25860037
[Journal Article] Mutations in biosynthetic enzymes for the protein linker region of chondroitin/dermatan/heparan sulfate cause skeletal and skin dysplasias.2015
- Author(s)
  Shuji Mizumoto, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  BioMed Research International
  
  Volume: 2015 Pages: 861752-861752
- DOI
  10.1155/2015/861752
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07951, KAKENHI-PUBLICLY-26110719, KAKENHI-PROJECT-25860037
[Journal Article] Cloning and characterization of a novel chondroitin sulfate/dermatan sulfate 4-O-endosulfatase from a marine bacterium.2015
- Author(s)
  Wenshuang Wang, Wenjun Han, Xingya Cai, Xiaoyu Zheng, Kazuyuki Sugahara, and Fuchuan Li
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 290 Pages: 7823-7832
- DOI
  10.1074/jbc.m114.629154
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25670018
[Journal Article] Receptor protein tyrosine phosphatase beta/zeta is a functional binding partner for vascular endothelial growth factor2015
- Author(s)
  Marina Koutsioumpa, Evangelia Poimenidi, Evangelia Pantazaka, Christina Theodoropoulou, Angeliki Skoura, Vasileios Megalooikonomou, Nelly Kieffer, Jose Courty, Shuji Mizumoto, Kazuyuki Sugahara, and Evangelia Papadimitriou.
- Journal Title
  
  Mol. Cancer
  
  Volume: 14 Pages: 19-19
- DOI
  10.1186/s12943-015-0287-3
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670018, KAKENHI-PUBLICLY-26110719, KAKENHI-PROJECT-25860037
[Journal Article] Novel chondroitin sulfate oligosaccharide motifs as biomarkers: insights into their involvement in brain development.2015
- Author(s)
  Kazuyuki Sugahara
- Journal Title
  
  Advances in Experimental Medicine and Biology
  
  Volume: 842 Pages: 165-183
- DOI
  10.1007/978-3-319-11280-0_11
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25670018
[Journal Article] Roles of glycosaminoglycans and glycanmimetics in tumor progression and metastasis2014
- Author(s)
  Basappa, Kanchugarakoppal S. Rangappa, Kazuyuki Sugahara
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: 31 Pages: 461-467
- DOI
  10.1007/s10719-014-9551-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25670018
[Journal Article] Sulfation patterns of exogenous chondroitin sulfate affect chondrogenic differentiation of ATDC5 cells2014
- Author(s)
  Daisuke Kawamura, Tadanao Funakoshi, Shuji Mizumoto, Kazuyuki Sugahara, and Norimasa Iwasaki
- Journal Title
  
  Journal of Orthopaedic Science
  
  Volume: 19 Pages: 1028-1035
- DOI
  10.1007/s00776-014-0643-y
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860037, KAKENHI-PUBLICLY-26110719
[Journal Article] Human Genetic Disorders and Knockout Mice Deficient in Glycosaminoglycan2014
- Author(s)
  Shuji Mizumoto, Shuhei Yamada, and Kazuyuki Sugahara
- Journal Title
  
  BioMed Research International
  
  Volume: 2014 Pages: 495764-495764
- DOI
  10.1155/2014/495764
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590071, KAKENHI-PROJECT-25860037, KAKENHI-PUBLICLY-26110719
[Journal Article] A novel eliminase from a marine bacterium that degrades hyaluronan and chondroitin sulfate.2014
- Author(s)
  Wenjun Han, Wenshuang Wang, Mei Zhao, Kazuyuki Sugahara, and Fuchuan Li
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 289 Pages: 27886-27898
- DOI
  10.1074/jbc.m114.590752
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25670018
[Journal Article] Effects of sesamin on the biosynthesis of chondroitin sulfate proteoglycans in human articular chondrocytes in primary culture2014
- Author(s)
  Peraphan Pothacharoen, Sumet Najarus, Jongkolnee Settakorn, Shuji Mizumoto, Kazuyuki Sugahara, and Prachya Kongtawelert
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: 31 Pages: 221-230
- DOI
  10.1007/s10719-013-9514-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860037
[Journal Article] Human genetic disorders caused by defective genes encoding biosynthetic enzymes for sulfated glycosaminoglycans2013
- Author(s)
  Shuji Mizumoto, Shiro Ikegawa, andKazuyuki Sugahara
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 288 Pages: 10953-10961
- DOI
  10.1074/jbc.r112.437038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066, KAKENHI-PROJECT-25860037
[Journal Article] Glycosaminoglycans are functional ligands for Receptor for Advanced Glycation End-products (RAGE) in tumors2013
- Author(s)
  Shuji Mizumoto, Kazuyuki Sugahara
- Journal Title
  
  FEBS Journal
  
  Volume: 280(10) Pages: 2462-2470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Expression of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase involved in chondroitin sulfate synthesis is responsible for pulmonary metastasis2013
- Author(s)
  Shuji Mizumoto, Moto Watanabe, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  BioMed Research International
  
  Volume: 2013 Pages: 656319-656319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] A sulfated glycosaminoglycan array for molecular interactions between glycosaminoglycans and growth factors or anti-glycosaminoglycan antibodies2013
- Author(s)
  Wataru Takada, Masao Fukushima, Peraphan Pothacharoen, Prachya Kongtawelert, Kazuyuki Sugahara
- Journal Title
  
  Analytical Biochemistry
  
  Volume: 435 Pages: 123-130
- DOI
  10.1016/j.ab.2013.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24110501
[Journal Article] Interaction of chondroitin sulfate and dermatan sulfate from various biological sources with heparin-binding growth factors and cytokines2013
- Author(s)
  Shuji Mizumoto, Duriya Fongmoon, Kazuyuki Sugahara
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: in press Pages: 619-632
- DOI
  10.1007/s10719-012-9463-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066, KAKENHI-PUBLICLY-24110501, KAKENHI-PROJECT-25860037
[Journal Article] Semaphorin 3A binds to the perineuronal nets via chondroitin sulfate type E motifs in rodent brains2013
- Author(s)
  Gunnar Dick, Chin Lik Tan, Joao Nuno Alves, Erich M. E. Ehlert, Gregory M. Miller, Linda C. Hsieh-Wilson, Kazuyuki Sugahara, Arie Oosterhof, Toin H. van Kuppevelt, Joost Verhaagen, James W. Fawcett, and Jessica C. F. Kwok
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 288 Pages: 27384-27395
- DOI
  10.1074/jbc.m111.310029
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24110501
[Journal Article] Mutations in B3GALT6, which encodes a glycosaminoglycan linker region enzyme, cause a spectrum of skeletal and connective tissue disorders2013
- Author(s)
  Masahiro Nakajima, Shuji Mizumoto et al.
- Journal Title
  
  Am J Hum Genet.
  
  Volume: in press Pages: 927-34
- DOI
  10.1016/j.ajhg.2013.04.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066, KAKENHI-PROJECT-24592230, KAKENHI-PROJECT-25293235, KAKENHI-PROJECT-25860037, KAKENHI-PROJECT-25860915
[Journal Article] Expression of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase involved in chondroitin sulfate synthesis is responsible for pulmonary metastasis2013
- Author(s)
  Mizumoto, S., Watanabe, M., Yamada, S., and Sugahara, K.
- Journal Title
  
  BioMed Research International
  
  Volume: 2013 Pages: 656319-656319
- DOI
  10.1155/2013/656319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066
[Journal Article] Mass preparation of oligosaccharides by hydrolysis of chondroitin sulfate polysaccharides with subcritical water microreaction system2013
- Author(s)
  Shuhei Yamada, Keiichiro Matsushima, Haruo Ura, Nobuyuki Miyamoto, Kazuyuki Sugahara
- Journal Title
  
  Carbohydr. Res.
  
  Volume: 371 Pages: 16-21
- DOI
  10.1016/j.carres.2013.01.024
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24110501, KAKENHI-PROJECT-24590071
[Journal Article] Clinical and radiographic features of the autosomal recessive form of brachyolmia caused by PAPSS2 mutations2013
- Author(s)
  Aritoshi Iida*, Pelin Ozlem Simsek-Kiper*, Shuji Mizumoto*, Touma Hoshino, Nursel Elcioglu, Eva Horemuzova, Stefan Geiberger, Gozde Yesil, Hulya Kayserili, Gulen Eda Unite, Koray Boduroglu, Shigehiko Watanabe, Hirofumi Ohashi, Yasemin Alanay, Kazuyuki Sugahara, Gen Nishimura, Shiro Ikegawa (*equal contribution)
- Journal Title
  
  Human Mutation
  
  Volume: 34
- DOI
  10.1002/humu.22377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860037
[Journal Article] De novo mutations in SLC35A2 encoding a UDP-galactose transporter cause early-onset epileptic encephalopathy.2013
- Author(s)
  Kodera H, Nakamura K, Osaka H, Maegaki Y, Haginoya K, Mizumoto S, Kato M, Okamoto N, Iai M, Kondo Y, Nishiyama K, Tsurusaki Y, Nakashima M, Miyake N, Hayasaka K, Sugahara K, Yuasa I, Wada Y, Matsumoto N, Saitsu H.
- Journal Title
  
  Hum Mutat.
  
  Volume: 34 Pages: 1708-14
- DOI
  10.1002/humu.22446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390081, KAKENHI-PROJECT-23590849, KAKENHI-PROJECT-23591497, KAKENHI-PUBLICLY-24110501, KAKENHI-PLANNED-24118007, KAKENHI-PROJECT-24249019, KAKENHI-PROJECT-24591500, KAKENHI-PROJECT-25293085, KAKENHI-PROJECT-25293235, KAKENHI-PROJECT-25860915
[Journal Article] Loss of dermatan sulfate epimerase (DSE) function results in musculocontractural Ehlers-Danlos syndrome2013
- Author(s)
  Thomas Muller, Shuji Mizumoto, Indrajit Suresh, Yoshie Komatsu, Julia Vodopiutz, Munis Dundar, Volker Straub, Arno Lingenhel, Andreas Melmer, Silvia Lechner, Johannes Zschocke, Kazuyuki Sugahara, Andreas R Janecke
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 22 Pages: 3761-3772
- DOI
  10.1093/hmg/ddt227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066, KAKENHI-PROJECT-25860037
[Journal Article] Glycosaminoglycans are functional ligands for Receptor for Advanced Glycation End-products (RAGE) in tumors2013
- Author(s)
  Mizumoto, S., and Sugahara, K.
- Journal Title
  
  FEBS Journal
  
  Volume: 280 Pages: 2462-2470
- DOI
  10.1111/febs.12156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066, KAKENHI-PROJECT-25670018, KAKENHI-PROJECT-25860037
[Journal Article] Highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences with bioctivities2013
- Author(s)
  Shuji Mizumoto, Saori Murakoshi, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fukui, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
- Journal Title
  
  Glycobiology
  
  Volume: 23 Pages: 155-168
- DOI
  10.1093/glycob/cws137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066, KAKENHI-PUBLICLY-24110501
[Journal Article] Specific interaction of the envelope glycoproteins E1 and E2 with liver heparin sulfate involved in the tissue tropismatic infection by hepatitis C virus2012
- Author(s)
  Kobayashi, F., Yamada, S., Taguwa, S., Naito, S., Tani, H., Matsuura, Y., and Sugahara, K.
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: 29 Pages: 211-220
- DOI
  10.1007/s10719-012-9388-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-24790451
[Journal Article] ISCSM2011 Chondroitin sulfate E-type structure at tumor cell surface is involved in experimental metastasis2012
- Author(s)
  Sugahara, K., and Mizumoto, S.
- Journal Title
  
  Advances in Experimental Medicine and Biology, (Biochemical Roles of Eukaryotic Cell Surface Macromolecules)
  
  Volume: 749 Pages: 33-45
- DOI
  10.1007/978-1-4614-3381-1_3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066
[Journal Article] Bone ana skin disorders caused by a disturbance in the bioynthesis of chondroitin sulfate and dermatan sulfate2012
- Author(s)
  Mizumoto, S., Sugahara, K.
- Journal Title
  
  Extracellular matrix : Pathobiology and signaling
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Chondroitin sulfate E-type structure at tumor cell surface is involved in experimental metastasis2012
- Author(s)
  Kazuyuki SUGAHRA, Shuji MIZUMOTO
- Journal Title
  
  Advances in Experimental Medicine and Biology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Glycosaminoglycan chain analysis and characterization (Glycosylation/Epimerization)2012
- Author(s)
  Shuji Mizumoto and Kazuyuki Sugahara
- Journal Title
  
  Methods in Molecular Biology,"Proteoglycans: Methods and Protocols"(Redini, Francoise, ed.)
  
  Volume: 836 Pages: 99-115
- DOI
  10.1007/978-1-61779-498-8_7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066
[Journal Article] Identification of amino acid residues required for the substrate specificity of human and mouse chondroitin sulfate hydrolase (conventional hyaluronidase-4)2012
- Author(s)
  Tomoyuki Kaneiwa, Anzu Miyazaki, Ryo Kogawa, Shuji Mizumoto, Kazuyuki Sugahara, and Shuhei Yamada
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 287 Pages: 42119-42128
- DOI
  10.1074/jbc.m112.360693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590071
[Journal Article] Chondroitin sulfate wobble motifs modulate the maintenance and differentiation of neural stem cells and their progeny2012
- Author(s)
  Purushothaman, A., Sugahara, K., and Faissner, A.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 287 Pages: 2935-2942
- DOI
  10.1074/jbc.r111.298430
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24110501
[Journal Article] Receptor for Advanced Glycation End Products (RAGE) Functions as a Receptor for Specific Sulfated Glycosaminoglycans, and Anti-RAGE Antibody or The Sulfated Glycosaminoglycans Delivered in vivo Inhibit Pulmonary Metastasis of Tumor Cells2012
- Author(s)
  Shuji Mizumoto, Jun Takahashi, Kazuyuki Sugahara
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 287(23) Pages: 18985-18994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Receptor for Advanced Glycation End Products (RAGE) Functions as a Receptor for Specific Sulfated Glycosaminoglycans, and Anti-RAGE Antibody or The Sulfated Glycosaminoglycans Delivered in vivo Inhibit Pulmonary Metastasis of Tumor Cells2012
- Author(s)
  Shuji MIZUMOTO, Jun TAKAHASHI, Kazuyuki SUGAHARA
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Receptor for Advanced Glycation EndProducts (RAGE) Functions as a Receptor for Specific Sulfated Glycosaminoglycans, and Anti-RAGE Antibody or The Sulfated Glycosaminoglycans Delivered in vivo Inhibit Pulmonary Metastasis of Tumor Cells2012
- Author(s)
  Mizumoto, S., Takahashi, J., and Sugahara, K.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 287 Pages: 99-115
- DOI
  10.1074/jbc.m111.313437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066
[Journal Article] Specific interaction of the envelope glycoproteins E1 and E2 with liver heparan sulfate involved in the tissue tropismatic infection by hepatitis C virus2012
- Author(s)
  Fumi Kobayashi, Shuhei Yamada, Shuhei Taguwa, Chikako Kataoka, Satomi Naito, Yoshiki Hama, Hideki Tani, Yoshiharu Matsuura, Kazuyuki Sugahara
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: 29(4) Pages: 211-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Hyaluronidases have strong hydrolytic activity toward chondroitin 4-sulfate comparable to that for hyaluronan2012
- Author(s)
  Tomoko Honda, Tomoyuki Kaneiwa, Shuji Mizumoto, Kazuyuki Sugahara, and Shuhei Yamada
- Journal Title
  
  Biomolecules
  
  Volume: 2 Pages: 549-563
- DOI
  10.3390/biom2040549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590071
[Journal Article] Unique heparan sulfate from shrimp heads exhibits a strong inhibitory effect on infections by dengue virus and Japanese encephalitis virus2011
- Author(s)
  Jiancheng Chen, Shuhei Yamada#, Yoshiki Hama, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Eunmi Kim, Takashi Kimura, Naonori Takahashi, Kazuya I. P. J. Hidari, Takashi Suzuki, Yasuo Suzuki, and Kazuyuki Sugahara#
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 412(1) Pages: 136-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in α-Thrombomodulin from Human Urine2011
- Author(s)
  Taishi Hashiguchi, Shuji Mizumoto, Yuko Nishimura, Jun-ichi Tamura, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286(38) Pages: 33003-33011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Demonstration of the hepatocyte growth factor signaling pathway in the in vitro neuritogenic activity of chondroitin sulfate from ray fish cartilage2011
- Author(s)
  Taishi Hashiguchi, Takanari Kobayashi, Duriya Fongmoon, Ajaya Kumar Shetty, Shuji Mizumoto, Nobuyuki Miyamoto, Toshikazu Nakamura, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Biochimica et Biophysica Acta (General Subjects)
  
  Volume: 1810(4) Pages: 406-413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain.2011
- Author(s)
  Akatsu C., Mizumoto S., Kaneiwa T., Maccarana M., Malmstrom A., Yamada S., Sugahara K.
- Journal Title
  
  Glycobiology 21(5)
  
  Pages: 565-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Demonstration of the Hepatocyte Growth Factor Signaling Pathway in the in vitro Neuritogenic Activity of Chondroitin Sulfate from Ray Fish Cartilage.2011
- Author(s)
  Hashiguchi Y., Kobayashi T., Fongmoon D., Shetty A.K., Mizumoto S., Miyamoto N., Nakamura T., Yamada S., Sugahara K.
- Journal Title
  
  Biochim.Biophys.Acta 1810(4)
  
  Pages: 406-413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Involvement of HNK-1 sulfotransferase in the biosynthesis of the GlcUA(3-O-sulfate)-Gal-Gal-Xyl tetrasaccharide found in ?-thrombomodulin from human urine2011
- Author(s)
  Taishi Hashiguchi, Shuji Mizumoto, Yuko Nishimura, Jun-ichi Tamura, Shuhei Yamada#, and Kazuyuki Sugahara#
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286(38) Pages: 33003-33011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Evolution of Glycosaminoglycans : Comparative Biochemical Study.2011
- Author(s)
  Yamada S., Sugahara K., Ozbek S.
- Journal Title
  
  Commun.Integr.Biol. (in press.)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Evolution of Glycosaminoglycans: Comparative Biochemical Study2011
- Author(s)
  Shuhei Yamada#, Kazuyuki Sugahara, and Suat Ozbek
- Journal Title
  
  Commun. Integr. Biol
  
  Volume: 4(2) Pages: 150-158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Unique heparan sulfate from shrimp heads exhibits a strong inhibitory effect on infections by dengue virus and Japanese encephalitis virus2011
- Author(s)
  Jiancheng Chen, Shuhei Yamada, Yoshiki Hama, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Eunmi Kim, Takashi Kimura, Naonori Takahashid, Kazuya Hidari, Takashi Suzuki, Yasuo Suzuki, Kazuyuki Sugahara
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 412(1) Pages: 136-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Faulty initiation of proteoglycan synthesis causes cardiac and joint defects.2011
- Author(s)
  Baasanjav S., Al-Gazali L., Hashiguchi T., Mizumoto S., Fischer B., Horn D., Seelow D., Ali B.R., Aziz S.A.A., Langer R., Saleh A.A.H., Becker C., Nurnberg G., Cantagrel V., Gleeson J.G., Gomez D., Michel J.-B., Stricker S., Lindner T.H., Nurnberg P., Sugahara K., Mundlos S., Hoffmann K.
- Journal Title
  
  Am.J.Hum.Genet. (in press.)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Demonstration of the Hepatocyte Growth Factor Signaling Pathway in the in vitro Neuritogenic Activity of Chondroitin Sulfate from Ray Fish Cartilage2011
- Author(s)
  Taishi Hashiguchi, Takanari Kobayashi, Duriya Fongmoon, Ajaya Kumar Shetty, Shuji Mizumoto, Nobuyuki Miyamoto, Toshikazu Nakamura, Shuhei Yamada#, and Kazuyuki Sugahara#
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1810(4) Pages: 406-413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Faulty initiation of proteoglycan synthesis causes cardiac and joint defects2011
- Author(s)
  Sevjidmaa Baasanjav, Lihadh Al-Gazali, Taishi Hashiguchi, Shuji Mizumoto, Bjoern Fischer, Denise Horn, Dominik Seelow, Bassam R. Ali, Samir A.A. Aziz, Ruth Langer, Ahmed A.H. Saleh, Christian Becker, Gudrun Nürnberg, Vincent Cantagrel, Joseph G. Gleeson, Delphine Gomez, Jean-Baptiste Michel, Sigmar Stricker, Tom H. Lindner, Peter Nürnberg, Kazuyuki Sugahara, Stefan Mundlos, Katrin Hoffmann
- Journal Title
  
  American Journal of Human Genetics
  
  Volume: 89(1) Pages: 15-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Paradoxical effects of chondroitin sulfate-E on Japanese encephalitis viral infection2011
- Author(s)
  Eunmi Kim, Megumi Okumura, Hirofumi Sawa, Tadaaki Miyazaki, Daisuke Fujikura, Shuhei Yamada, Kazuyuki Sugahara, Michihito Sasaki, Takashi Kimura
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 409(4) Pages: 717-722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in α -Thrombomodulin from Human Urine2011
- Author(s)
  Taishi Hashiguchi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 33003-33011
- DOI
  10.1074/jbc.m111.279174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057, KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066
[Journal Article] Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain2011
- Author(s)
  Chizuru Akatsu, Shuji Mizumoto, Tomoyuki Kaneiwa, Marco Maccarana, Anders Malmström, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Glycobiology
  
  Volume: 21(5) Pages: 565-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain2011
- Author(s)
  Akatsu, C., Mizumoto, S., Kaneiwa, T., Maccarana, M., Malmstrom,. A., Yamada, S., Sugahara, K.
- Journal Title
  
  Glycobiology
  
  Volume: 21 Pages: 565-574
- DOI
  10.1093/glycob/cwq208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Demonstration of the Hepatocyte Growth Factor Signaling Pathway in the in vitro Neuritogenic Activity of Chondroitin Sulfate from Ray Fish Cartilage2011
- Author(s)
  Taishi Hashiguchi
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: 1810 Pages: 406-413
- DOI
  10.1016/j.bbagen.2011.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057, KAKENHI-PROJECT-23390016
[Journal Article] Unique heparan sulfate from shrimp heads exhibits a strong inhibitory effect on infections by dengue virus and Japanese encephalitis virus2011
- Author(s)
  Jiancheng Chen
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 412 Pages: 136-142
- DOI
  10.1016/j.bbrc.2011.07.059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057, KAKENHI-PROJECT-23390016
[Journal Article] Disorder of Biosynthesis of Dermatan Sulfate Causes a New Type of Ehlers-Danlos Syndrome2011
- Author(s)
  Kazuyuki Sugahara and Shuji Mizumoto
- Journal Title
  
  TIGG
  
  Volume: 23(132) Issue: 132 Pages: 197-199
- DOI
  10.4052/tigg.23.197
- ISSN
  0915-7352, 1883-2113
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066
[Journal Article] Paradoxical effects of chondroitin sulfate-E on Japanese encephalitis viral infection.2011
- Author(s)
  Kim, E., Okumura, M., Sawa, H., Miyazaki, T., Fujikura, D., Yamada, S., Sugahara, K., Sasaki, M., Kimura, T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 409 Pages: 717-722
- DOI
  10.1016/j.bbrc.2011.05.072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790317
[Journal Article] Faulty initiation of proteoglycan synthesis causes cardiac and joint defects.2011
- Author(s)
  Baasanjav, S., Al-Gazali, L., Hashiguchi, T., Mizumoto, S., Fischer, B., Horn, D., Seelow, D., Ali, B.R., Aziz, S.A.A., Langer, R., Saleh,A.A.H., Becker, C., Nunberg,G., Cantagrel, V., Gleeson, J.G., Gomez, D., Michel, J-.B., Stricker, S., Lindner, T.H., Nunberg, P., Sugahara, K., Mundlos, S., Hoffmann, K.
- Journal Title
  
  American Journal of Human Genetics
  
  Volume: 89 Pages: 15-27
- DOI
  10.1016/j.ajhg.2011.05.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066
[Journal Article] Evolution of Glycosaminoglycans : Comparative Biochemical Study2011
- Author(s)
  Shuhei Yamada, Kazuyuki Sugahara, Suat Özbek
- Journal Title
  
  Communicative & Integrative Biology
  
  Volume: 4 Pages: 150-158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Loss-of-function mutations of CHST14 in a new type of Ehlers-Danlos syndrome.2010
- Author(s)
  Miyake N., Kosho T., Mizumoto S., Furuichi T., Hatamochi A., Nagashima Y., Arai E., Takahashi K., Kawamura R., Wakui K., Takahashi J., Kato H., Yasui H., Ishida T., Ohashi H., Nishimura G., Shiina M., Saitsu H., Tsurusaki Y., Doi H., Fukushima Y., Ikegawa S., Yamada S., Sugahara K., Matsumoto N.
- Journal Title
  
  Hum.Mutat.(Equal contribution) 31(8)
  
  Pages: 966-974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Development of a Mouse Monoclonal Antibody Against the Chondroitin Sulfate-protein Linkage Region Derived from Shark Cartilage2010
- Author(s)
  Chizuru Akatsu, Duriya Fongmoon, Shuji Mizumoto, Jean-Claude Jacquinet, Prachya Kongtawelert, Shuhei Yamada#, and Kazuyuki Sugahara#
- Journal Title
  
  Glycoconjugate J
  
  Volume: 27(4) Pages: 387-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Identification of Human Hyaluronidase-4 as a Novel Chondroitin Sulfate Hydrolase That Preferentially Cleaves the Galactosaminidic Linkage in the Trisulfated Tetrasaccharide Sequence2010
- Author(s)
  Tomoyuki Kaneiwa, Shuji Mizumoto, Kazuyuki Sugahara, and Shuhei Yamada#
- Journal Title
  
  Glycobiology
  
  Volume: 20(3) Pages: 300-309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Analysis of the structure and neuritogenic activity of chondroitin sulfate/dermatan sulfate hybrid chains from porcine fetal membranes.2010
- Author(s)
  Hashiguchi T., Mizumoto S., Yamada S., Sugahara K.
- Journal Title
  
  Glycoconjugate J. 27(1)
  
  Pages: 49-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Synthesis of the glycosaminoglycan-protein linkage tetraosyl peptide moieties of betaglycan, which serve as a hexosamine acceptor for enzymatic glycosyl transfer.2010
- Author(s)
  Tamura J., Nakamura-Yamamoto T., Nishimura Y., Mizumoto S., Takahashi J., Sugahara K.
- Journal Title
  
  Carbohydr.Res. 345(15)
  
  Pages: 2115-2123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Structure of pleiotrophin-and hepatocyte growth factor-binding sulfated hexasaccharide determined by biochemical and computational approaches.2010
- Author(s)
  Li F., Nandini C.D., Hattori T., Bao X., Murayama D., Nakamura T., Fukushima N., Sugahara K.
- Journal Title
  
  J.Biol.Chem. 285(36)
  
  Pages: 27673-27685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] A non-sulfated chondroitin stabilizes membrane tubulation in cnidarian organelles.2010
- Author(s)
  Adamczyk P., Zenkert C., Balasubramanian P.G., Yamada S., Murakoshi S., Sugahara K., Hwang J.S., Gojobori T., Holstein T.W., Ozbek S.
- Journal Title
  
  J.Biol.Chem. 285(33)
  
  Pages: 25613-25623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Involvement of chondroitin sulfate E in the liver tumor focal formation of murine osteosarcoma cells.2009
- Author(s)
  Basappa Murugan S., Sugahara K.N., Lee C.M., ten Dam G.B., van Kuppevelt T.H., Miyasaka M., Yamada S., Sugahara K.
- Journal Title
  
  Glycobiology 19(7)
  
  Pages: 735-742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Important role of heparan sulfate in postnatal islet growth and insulin secretion.2009
- Author(s)
  Takahashi I., Noguchi N., Nata K., Yamada S., Kaneiwa T., Mizumoto S., Ikeda T., Sugihara K., Asano M., Yoshikawa T., Yamauchi A., Shervani N. J., Uruno A., Kato I., Unno M., Sugahara K., Takasawa S., Okamoto H., Sugawara A.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 383(1)
  
  Pages: 113-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Structural and Functional Changes of Sulfated Glycosaminoglycans in Xenopus laevis during Embryogenesis2009
- Author(s)
  Yamada S., Onishi M., Fujinawa R., Tadokoro Y., Okabayashi K., Asashima M., Sugahara K.
- Journal Title
  
  Glycobiology 19(5)
  
  Pages: 488-498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Structural and Functional Changes of Sulfated Glycosaminoglycans in Xenopus laevis during Embryogenesis2009
- Author(s)
  huhei Yamada#, Masako Onishi, Reiko Fujinawa, Yuko Tadokoro, Koji Okabayashi, Makoto Asashima, and Kazuyuki Sugahara
- Journal Title
  
  Glycobiology
  
  Volume: 19(5) Pages: 488-498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Isolation and Characterization of a Novel Chondroitin Sulfate from Squid LiverIntegument Rich in N-Acetylgalactosamine(4, 6-O-disulfate) and Glucuronate(3-O-sulfate) Residues2009
- Author(s)
  Ajaya Kumar Shetty, Takanari Kobayashi, Shuji Mizumoto, Masaki Narumi, YoshiakiKudo, Shuhei Yamada#, and Kazuyuki Sugahara#
- Journal Title
  
  Carbohydr. Res
  
  Volume: 344(12) Pages: 1526-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Isolation and characterization of a novel chondroitin sulfate from squid liver integument rich in N-acetylgalactosamine(4,6-O-disulfate) and glucuronate(3-O-sulfate) residues.2009
- Author(s)
  Shetty A.K., Kobayashi T., Mizumoto S., Narumi M., Kudo Y., Yamada S., Sugahara K.
- Journal Title
  
  Carbohydr.Res.(Equal contribution) 344(12)
  
  Pages: 1526-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Chondroitin 4-O-sulfotransferase-1 is required for somitic muscle development and motor axon guidance in zebrafish2009
- Author(s)
  Mizumoto S., Mikami T., Yasunaga D., Kobayashi N., Yamauchi H., Miyake A., Itoh N., Kitagawa H., Sugahara K.
- Journal Title
  
  Biochem.J.(Equal contribution) 419(2)
  
  Pages: 387-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Important Role of Heparan Sulfate in Postnatal Islet Growth and Insulin Secretion2009
- Author(s)
  Iwao Takahashi, Naoya Noguchi, Koji Nata, Shuhei Yamada, Tomoyuki Kaneiwa, Shuji Mizumoto, Takayuki Ikeda, Kazushi Sugihara, Masahide Asano, Takeo Yoshikawa, Akiyo Yamauchi, Nausheen Jamal Shervani, Akira Uruno, Ichiro Kato, Michiaki Unno, Kazuyuki Sugahara, Shin Takasawa, Hiroshi Okamoto, and Akira Sugawara
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 383(1) Pages: 113-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Chondroitin Hydrolase in Caenorhabditis elegans2009
- Author(s)
  huhei Yamada#, Shuji Mizumoto, and Kazuyuki Sugahara
- Journal Title
  
  Trends Glycosci. Glycotechnol
  
  Volume: 21(119) Pages: 149-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Chondroitin Hydrolase in Caenorhabditis elegans.2009
- Author(s)
  Yamada S., Mizumoto S., Sugahara K.
- Journal Title
  
  Trends Glycosci.Glycotechnol. 21(119)
  
  Pages: 149-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Identification of Chondroitin Sulfate Glucuronyltransferase as Chondroitin Synthase-3 Involved in Chondroitin Polymerization: Chondroitin Polymerization Is Achieved by Multiple Enzyme Complexes Consisting of Chondroitin Synthase Family Members.2008
- Author(s)
  Izumikawa, T., Koike, T., Shiozawa ,S., Sugahara, K., Tamura, J., and Kitagawa, H.
- Journal Title
  
  J. Biol. Chem. 283(17)
  
  Pages: 11396-11406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390025
[Journal Article] Sulfation of the Galactose Residues in the Glycosaminoglycan-Protein Linkage Region by Recombinant Human Chondroitin 6-Osulfotransferase-1.2008
- Author(s)
  Kitagawa, H., Tsutsumi, K., Ikegami-Kazuhara,A., Nadanaka, S., Goto, F., Ogawa, T., and Sugahara, K.
- Journal Title
  
  J. Biol. Chem. 283(41)
  
  Pages: 27438-27443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390025
[Journal Article] Identification of a novel chondroitin hydrolase in Caenorhabditis elegans.2008
- Author(s)
  Kaneiwa, T., Yamada, S., Mizumoto, S., Montano, A. M., Mitani, S., and Sugahara, K.
- Journal Title
  
  J Biol. Chem. 283(22)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] 2-O-phosphorylation of xylose and 6-O-sulfation of galactose in the protein linkage region of glycosaminoglycans influence the glucuronyltransferase-I activity involved in the linkage region's synthesis.2008
- Author(s)
  Tone, Y., Pedersen, L. C., Yamamoto, T., Izumikawa, T., Kitagawa, H., Nishihara, J., Tamura, J., Negishi, M., and Sugahara, K.
- Journal Title
  
  J. Biol. Chem. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Determination of Iduronic Acid and Glucuronic Acid in Sulfated Chondroitin/Dermatan Hybrid Chains by 1H-Nuclear Magnetic Resonance Spectroscopy.2008
- Author(s)
  Li, F., Yamada, S., Basappa, Shetty, A. K., Sugiura, M., and Sugahara, K.
- Journal Title
  
  Glycoconjugate J. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] 2-O-Phosphorylation of Xylose and 6-O-Sulfation of Galactose in the Protein Linkage Region of Glycosaminoglycans Influence the Glucuronyltransferase-I Activity Involved in the Linkage Region Synthesis.2008
- Author(s)
  Tone, Y., Pedersen, L. C., Yamamoto, T., Izumikawa, T., Kitagawa, H., Nishihara, J., Tamura, J., Negishi, M., and Sugahara, K.
- Journal Title
  
  J. Biol. Chem. 283(24)
  
  Pages: 16801-16807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390025
[Journal Article] Expression of rib-1, a Caenorhabditis elegans Homolog of the Human Tumor Suppressor EXT Genes is indispensable for heparan sulfate synthesis and embryonic morphogenesis.2007
- Author(s)
  Kitagawa, H., Izumikawa, T., Mizuguchi, S., Dejima, K., Nomura, K. H., Egusa, N., Taniguchi, F., Tamura, J., Gengyo-Ando, K., Mitani, S., Nomura, K., Sugahara, K.
- Journal Title
  
  J. Biol. Chem. 282 (11)
  
  Pages: 8533-8544
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Glycosaminoglycans in Hydra magnipapillata (Hydrozoa, Cnidaria): demonstration of chondroitin in the developing nematocyst, sting organelle, and structural characterization of glycosaminoglycans.2007
- Author(s)
  Yamada, S., Morimoto, H., Fujisawa, T., and Sugahara, K.
- Journal Title
  
  Glycobiology 17(8)
  
  Pages: 886-894
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Novel sulfated octa- and decasaccharides from squid cartilage chondroitin sulfate-E: Sequencing and their application for determination of the epitope structure of monoclonal antibody MO-2252007
- Author(s)
  Deepa, S. S., Kalayanamitra, K, Ito, Y., Kongtawelert, P, Fukui, S., Yamada, S., Mikami, T., and Sugahara, K.
- Journal Title
  
  Biochemistry 46(9)
  
  Pages: 2453-2465
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Neuritogenic activity of chondroitin/dermatan sulfate hybrid chains of embryonic pig brain and their mimicry from shark liver: Involvement of the pleiotrophin and hepatocyte growth factor signaling pathways.2007
- Author(s)
  Li, F., Shetty, A. K., and Sugahara, K.
- Journal Title
  
  J. Biol. Chem. 282(5)
  
  Pages: 2956-2966
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Biosynthesis ofglycosaminoglycans and proteoglycans.2007
- Author(s)
  Uyama, T., Kitagawa, H., Sugahara, K.
- Journal Title
  
  Comprehensive Glycoscience (Kamerling J. P., ed. ) Elsevier (Amsterdam) vol. 3, 25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Two related but distinct chondroitin sulfate mimetope octasaccharide sequences recognized by monoclonal antibody WF6.2007
- Author(s)
  Pothacharoen, P., Kalayanamitra, K., Deepa, S. S., Fukui, S., Hattori, T., Fukushima, N., Hardingham, T., Kongtawelert, P., and Sugahara, K.
- Journal Title
  
  J. Biol. Chem. 282(48)
  
  Pages: 35232-35246
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Chondroitin/dermatan sulfate in the central nervous system.2007
- Author(s)
  Sugahara, K., and Mikami, T.
- Journal Title
  
  Curr. Opin. Struct. Biol. 17
  
  Pages: 536-545
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Occurrence of a non-sulfated chondroitin proteoglycan in the dried saliva of collocalia swiftlets (edible bird's nest).2007
- Author(s)
  Nakagawa, H., Hama, Y., Sumi, T., Li, S. C., Maskos, K., Kalayanamitra, K., Mizumoto, S., Sugahara, K., and Li, Y. T.
- Journal Title
  
  Glycobiology 17(2)
  
  Pages: 157-164
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Structural Determination of Novel Sulfated Octasaccharides Isolated from Chondroitin Sulfate of Shark Cartilage and Their Application for Characterizing Monoclonal Antibody Epitopes.2007
- Author(s)
  Deepa, S. S., Yamada, S., Fukui, S., and Sugahara, K.
- Journal Title
  
  Glycobiology 17(6)
  
  Pages: 631-645
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Functions of Chondroitin Sulfate/Dermatan Sulfate Chains in Brain Development : Critical Roles of E and iE Disaccharide Units Recognized by Single Chain Antibody GD3G72007
- Author(s)
  Purushothaman, A., Fukuda, J., Mizumoto, S., Ten Dam, G. B., van Kuppevelt, T. H., Kitagawa, H., Mikami, T., and Sugahara, K.
- Journal Title
  
  J. Biol. Chem. 282(27)
  
  Pages: 19442-19452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390025
[Journal Article] Functions of Chondroitin Sulfate/Dermatan Sulfate Chains in Brain Development: Critical Roles of E and iE Disaccharide Units Recognized by a Single Chain Antibody GD3G7.2007
- Author(s)
  Purushothaman, A., Fukuda, J., Mizumoto, S., ten Dam, G. B., van Kuppevelt, T. H., Kitagawa, H., Mikami, T., and Sugahara K.
- Journal Title
  
  J. Biol. Chem. 282(27)
  
  Pages: 19442-19452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Chondroitinase-mediated degradation of rare 3-O-sulfated glucuronic acid in functional oversulfated chondroitin sulfate K and E.2007
- Author(s)
  Fongmoon, D., Shetty, A. K., Basappa, Yamada, S., Sugiura, M., Kongtawelert, P., and Sugahara, K.
- Journal Title
  
  J. Biol. Chem. 282(51)
  
  Pages: 36895-36904
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Involvement of Chondroitin Sulfate Synthase-3 (Chondroitin Synthase-2) in Chondroitin Polymerization through Its Interaction with Chondroitin Synthase-1 or Chondroitin Polymerizing Factor.2007
- Author(s)
  Izumikawa, T., Uyama, T., Okuura, Y., Sugahara, K., and Kitagawa, H.
- Journal Title
  
  Biochem. J. 403(3)
  
  Pages: 545-552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390025
[Journal Article] Chondroitin/dermatan sulfate in the central nervous system.2007
- Author(s)
  Sugahara, K.
- Journal Title
  
  Curr. Opin. Struct. Biol. 17
  
  Pages: 536-545
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Heparan sulfate polymerization in Drosophila.2006
- Author(s)
  Izumikawa, T., Egusa, N., Taniguchi, F., Sugahara, K., Kitagawa, H.
- Journal Title
  
  J. Biol. Chem. 281 (4)
  
  Pages: 1929-1934
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Chondroitin sulfate/dermatan sulfate hybrid chains in the development of cerebellum: Spatiotemporal regulation of the expression of critical disulfated disaccharides by specific sulfotransferases.2006
- Author(s)
  Mitsunaga, C., Mikami, T., Mizumoto, S., Fukuda, J., and Sugahara, K.
- Journal Title
  
  J. Biol. Chem. 281(26)
  
  Pages: 18942-18952
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Chondroitin 4-O-sulfotransferase-1 regulates "E" disaccharide expression of chondroitin sulfate required for herpes simplex virus infectivity.2006
- Author(s)
  Uyama, T., Ishida, M., Izumikawa, T., Trybala, E., Tufaro, F., Bergstrom, T., Sugahara, K., and Kitagawa, H.
- Journal Title
  
  J. Biol. Chem. 281(50)
  
  Pages: 38668-38674
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] G. C. elegans pharyngeal morphogenesis requires both de novo synthesis of pyrimidines and synthesis of heparan sulfate proteoglycans2006
- Author(s)
  Franks, D. M., Izumikawa, T., Kitagawa, H., Sugahara, K., Okkema, P.
- Journal Title
  
  Dev. Biol. 296 (2)
  
  Pages: 409-420
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Composition of perineuronal net extracellular matrix in rat brain: A different disaccharide composition for the net-associated proteoglycans.2006
- Author(s)
  Deepa, S. S. Carulli, D., Galtrey, C., Rhodes, K., Fukuda, J., Mikami, T., Sugahara, K., and Fawcett, J. W.
- Journal Title
  
  J. Biol. Chem. 281(26)
  
  Pages: 17789-17800
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Biosynthesis of heparin and heparan sulfate.2005
- Author(s)
  Mizumoto, S., Kitagawa, H., Sugahara, K.
- Journal Title
  
  Chemistry and Biology of Heparin and Heparan sulfate (Garg, H. G., Linhardt, R. J., and Hales, C. A., eds. ), Elsevier, Oxford, UK. 40
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Demonstration of the pleiotrophin-binding oligosaccharide sequences isolated from chondroitin sulfate/dermatan sulfate hybrid chains of embryonic pig brains.2005
- Author(s)
  Bao, X., Muramatsu, T., Sugahara, K.
- Journal Title
  
  J. Biol. Chem. 280 (42)
  
  Pages: 35318-35328
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Nematode chondroitin polymerizing factor showing cell/organ-specific expression is indispensable for chondroitin synthesis and embryonic cell division.2004
- Author(s)
  Izumikawa, T., Kitagawa, H., Mizuguchi, S., Nomura, K. H., Nomura, K., Tamura, J., Gengyo-Ando, K., Mitani, S., Sugahara, K.
- Journal Title
  
  J. Biol. Chem. 279 (51)
  
  Pages: 53755-53761
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Loss of chondroitin 6-O-sulfotransferase-1 function results in severe human chondrodysplasia with progressive spinal involvement.2004
- Author(s)
  Thiele, H., Sakano, M., Kitagawa, H., Sugahara, K,. Rajab, A., Hohne, W., Leschik, G, Nurnberg, P., Mundlos, S.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 101 (27)
  
  Pages: 10155-10160
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Molecular cloning and expression of a second chondroitin N-acetylgalactosaminyltransferase involved in the biosynthetic initiation and elongation of chondroitin/dermatan sulfate.2003
- Author(s)
  Uyama, T., Kitagawa, H., Tanaka, J., Tamura, J., Ogawa, T., Sugahara K
- Journal Title
  
  J. Biol. Chem. 278 (5)
  
  Pages: 3072-3078
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Recognition of glycosaminoglycans by midkine.2003
- Author(s)
  Muramatsu, T., Muramatsu, H., Kaneda, N., Sugahara, K.
- Journal Title
  
  Methods in Enzymol., (Lee, Y. C., and . Lee R. T. eds. ), Academic Press, New York 363
  
  Pages: 11-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Heterogeneity of the chondroitin sulfate portion of phosphacan/6B4 proteoglycan regulates its binding affinity for pleiotrophin/HB-GAM.2003
- Author(s)
  Maeda, N., He, J., Yajima, Y, Mikami, T., Sugahara. K., Yabe, T.
- Journal Title
  
  J. Biol. Chem. 278 (37)
  
  Pages: 35805-35811
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Crystal structure of an 1, 4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis.2003
- Author(s)
  Pedersen, L. C., Dong, J., Taniguchi, F., Kitagawa, H., Krahn, J., Pedersen, L. G., Sugahara, K., Negishi, M.
- Journal Title
  
  J. Biol. Chem. 278 (16)
  
  Pages: 14420-14428
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate2003
- Author(s)
  Sugahara, K.
- Journal Title
  
  Curr. Opin. Struct. Biol. 13
  
  Pages: 612-620
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate2003
- Author(s)
  Sugahara, K., Mikami, T., Uyama, U., Mizuguchi, S., Nomura, K., Kitagawa, H.
- Journal Title
  
  Curr. Opin. Struct. Biol. 13(5)
  
  Pages: 612-620
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Oversulfated chondroitin/dermatan sulfates containing GlcA 1/IdoA 1-3GalNAc(4, 6-O-disulfate)interact with L- and P-selectin and chemokines.2002
- Author(s)
  Kawashima, H., Atarashi, K., Hirose, M., Hirose, J., Yamada, S., Sugahara, K., Miyasaka, M.
- Journal Title
  
  J. Biol. Chem. 277 (15)
  
  Pages: 12921-12930
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082207
[Journal Article] Heparin and heparan sulfate biosynthesis (comprehensive review).2002
- Author(s)
  菅原一幸
- Journal Title
  
  IUBMB Life 54(4)
  
  Pages: 163-175
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470493
[Journal Article] Heparin and heparan sulfate biosynthesis (comprehensive review).2002
- Author(s)
  Sugahara, Kazuyuki
- Journal Title
  
  IUBMB Life 54(4)
  
  Pages: 163-175
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470493
[Presentation] Loss-of-function mutation of glucuronyltransferase-I causes skeletal dysplasia in a consanguineous clan from the island of Nias/Indonesia2015
- Author(s)
  ◯Shuji Mizumoto, Birgit S. Budde, Ryo Kogawa, Christian Becker, Janine Altmuller, Holger Thiele, Franz Ruschendorf, Mohammad R. Toliat, Gerrit Kaleschke, Johannes M. Hammerle, Wolffang Hahne, Kazuyuki Sugahara, Peter Nurnberg, Ingo Kennerknecht
- Organizer
  9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Ewha Womans University (Seoul, Korea)
- Year and Date
  2015-08-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] コンドロイチン・デルマタン・ヘパラン硫酸の生合成に関わるグルクロン酸転移酵素-Iの変異(P140L)による骨疾患の糖鎖生物学的研究2015
- Author(s)
  ○水本秀二, Birgit S. Budde, 古川諒, Christian Becker, Janine Altmuller, Holger Thiele, Franz Ruschendorf, Mohammad R. Toliat, Gerrit Kaleschke, Johannes M. Hammerle, Wolffang Hohne, 菅原一幸, Peter Nurnberg, Ingo Kennerknecht
- Organizer
  第７９回日本生化学会中部支部例会
- Place of Presentation
  信州大学松本キャンパス（松本）
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] グリコサミノグリカンの生合成に関わるグルクロン酸転移酵素-Iの新規変異による骨疾患の糖鎖生物学的研究2015
- Author(s)
  ○水本秀二, Birgit S. Budde, 古川諒, Christian Becker, Janine Altmuller, Holger Thiele, Franz Ruschendorf, Mohammad R. Toliat, Gerrit Kaleschke, Johannes M. Hammerle, Wolffang Hohne, 菅原一幸, Peter Nurnberg, Ingo Kennerknecht
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京大学（東京）
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] グリコサミノグリカンの生合成に関わるグルクロン酸転移酵素-Iの変異によるインドネシアのニアス島で見つかった骨疾患2015
- Author(s)
  ◯Shuji Mizumoto, Birgit S. Budde, Ryo Kogawa, Christian Becker, Janine Altmuller, Holger Thiele, Franz Ruschendorf, Mohammad R. Toliat, Gerrit Kaleschke, Johannes M. Hammerle, Wolffang Hohne, Kazuyuki Sugahara, Peter Nurnberg, Ingo Kennerknecht
- Organizer
  第３８回日本分子生物学会年会・第８８回日本生化学会大会・合同大会
- Place of Presentation
  神戸ポートアイランド（神戸）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] 低身長を特徴とする遺伝性骨疾患はグリコサミノグリカンの生合成に関わるグルクロン酸転移酵素-Iの変異によって引き起こされる2015
- Author(s)
  ◯水本秀二、Birgit S. Budde、古川諒、Peter Nurnberg、Ingo Kennerknecht、菅原一幸
- Organizer
  糖鎖科学中部拠点　第１２回若手の力フォーラム
- Place of Presentation
  名城大学（名古屋）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] サケ鼻軟骨由来のコンドロイチン硫酸プロテオグリカンの構造解析2015
- Author(s)
  横井友哉、松崎南美、桝谷晃明、坪井誠、菅原一幸、山田修平
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザインクリエイティブセンター神戸（神戸）
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] PAPS合成酵素2の変異は常染色体劣性型短脊柱症を引き起こす2014
- Author(s)
  水本秀二, 飯田有俊, Pelin Ozlem Simsek-Kiper, 星野冬馬, Nursel Elcioglu, Eva Horemuzova, Stefan Geiberger, Gozde Yesil, Hulya Kayserili, Gulen Eda Utine, Koray Boduroglu, 渡邉成彦, 大橋博文, Yasemin Alanay, 西村玄, 池川志郎, 菅原一幸
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋大学（名古屋）
- Year and Date
  2014-08-11
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] Development of novel monoclonal antibodies against chondroitin sulfate, and their application to glycobiology and glycopathology2014
- Author(s)
  Peraphan Pothacharoen, Duriya Fongmoon, Shuji Mizumoto, Kazuyuki Sugahara,、Prachya Kongtawelert
- Organizer
  6th Asian Community of Glycoscience and Glycotechnology (ACGG)
- Place of Presentation
  University of Hyderabad(インド)
- Year and Date
  2014-12-08
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] ヒトヒアルロニダーゼの基質認識に必要なアミノ酸残基の解析2014
- Author(s)
  岩月遥奈、水本秀二、金岩知之、菅原一幸、山田修平
- Organizer
  第60回日本薬学会東海支部総会
- Place of Presentation
  鈴鹿医療大学（鈴鹿）
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Integrated neuroglycobiology for proteoglycans and chondroitin sulfate-binding proteins2014
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, Kosei Takeuchi, Yoshiaki Nakayama, Akira Kurosaka, Keiichiro Matsushima, Nobuyuki Miyamoto, Wataru Takada, Hirofumi Kodera, Naomichi Matsumoto, Hirotomo Saitsu, Gunnar Dick, James W. Fawcett, Jessica C. F. Kwok
- Organizer
  International Symposium on Glyco-Neuroscience
- Place of Presentation
  Awaji
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Effects of Sesamin on the Biosynthesis of Chondroitin Sulfate Proteoglycans in Human Articular Chondrocytes in Primary Culture2014
- Author(s)
  Peraphan Pothacharoen, Sumet Najarus, Jongkolnee Settakorn, Shuji Mizumoto, Kazuyuki Sugahara, Prachya Kongtawelert
- Organizer
  Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research
- Place of Presentation
  Hawai Hotel Hilton(米国)
- Year and Date
  2014-11-20
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] Spondyloepimetaphyseal dysplasia and Ehlers-Danlos syndrome caused by mutations of glycosaminoglycan biosynthetic enzymes, GalT-II and DS-epimerase2014
- Author(s)
  Shuji Mizumoto, Masahiro Nakajima, Thomas Muller Noriko Miyake, Ryo Kogawa, Yoshie Komatsu, Naomichi Matsumoto, Andreas R Janecke, Shiro Ikegawa, Kazuyuki Sugahara
- Organizer
  Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research
- Place of Presentation
  Hilton Hotel (Hawaii, USA)
- Year and Date
  2014-11-19
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] コンドロイチン硫酸代謝におけるヒアルロニダーゼの役割2014
- Author(s)
  山田修平、本田智子、金岩知之、水本秀二、菅原一幸
- Organizer
  第46回日本結合組織学会学術大会第61回マトリックス研究会大会合同学術集会
- Place of Presentation
  ウインク愛知（名古屋）
- Year and Date
  2014-06-06
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Effects of Sesamin on the Biosynthesis of Chondroitin Sulfate Proteoglycans in Human Articular Chondrocytes in Primary Culture2014
- Author(s)
  Peraphan Pothacharoen, Sumet Najarus, Jongkolnee Settakorn, Shuji Mizumoto, Kazuyuki Sugahara, Prachya Kongtawelert
- Organizer
  Gordon Conference on Proteoglycans
- Place of Presentation
  Proctor Academy(米国)
- Year and Date
  2014-07-07
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] Mechanism of glycosaminoglycan -mediated tumor metastasis2014
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto
- Organizer
  The 27th International Carbohydrate Symposium
- Place of Presentation
  Indian Institute of Science (India)
- Year and Date
  2014-01-15
- Invited
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Mass preparation of oligosaccharides with intestinal absorption capacity by hydrolysis of chondroitin sulfate polysaccharides with subcritical water microreaction system2013
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, and Nobuyuki Miyamoto
- Organizer
  The 13th International Conference on Functional and Medical Foods with Bioactive Compounds : Science and Practical Applications/The First International Symposium of Academic Society for Functional Foods and Bioactive Compounds
- Place of Presentation
  The Kyoto Prefectural University (Kyoto)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Novel Class of Tetrahydropyridine-fused Pyrazoles, Isoxazolines, and HS-Mimetic Small Molecules as Anti-cancer Agents2013
- Author(s)
  Rangappa KS, Basappa, Mantelingu K, Sadashiva MP, Feng Li, Gautam Sethi, Kazuyuki Sugahara
- Organizer
  The 14th tetrahedron symposium
- Place of Presentation
  Millennium Gloucester Hotel London Kensington (オーストリア)
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] Development of novel monoclonal antibodies against chondroitin sulfate, and their application to glycobiology and glycopathology2013
- Author(s)
  Peraphan Pothacharoen, Duriya Fongmoon, Shuji Mizumoto, Kazuyuki Sugahara,Prachya Kongtawlert
- Organizer
  The 5th annual conference for Asian Communications of Glycobiology and Glycotechnology
- Place of Presentation
  Khon Kaen University (タイ国)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Development of novel monoclonal antibodies against chondroitin sulfate, and their application to glycobiology and glycopathology2013
- Author(s)
  Peraphan Pothacharoen, Duriya Fongmoon, Shuji Mizumoto, Kazuyuki Sugahara,Prachya Kongtawlert
- Organizer
  The 5th annual conference for Asian Communications of Glycobiology and Glycotechnology
- Place of Presentation
  Khon Kaen University(タイ国)
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences involved in brain development2013
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Kittiwan Kalayanamitra, Shuhei Yamada, and Prachya Kongtawelert
- Organizer
  8th International Conference on Proteoglycans
- Place of Presentation
  Frankfurt, Germany
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Receptor for Advanced Glycation End-products (RAGE) Functions as Receptor for Sulfated Glycosaminoglycans (GAGs) : Anti-RAGE Antibody or Sulfated GAGs Inhibit Lung Metastasis of Tumor Cells2013
- Author(s)
  Kazuyuki Sugahara, Jun Takahashi, Shuji Mizumoto
- Organizer
  22nd International Symposium on Glycoconjugates
- Place of Presentation
  Dalian Institute of Chemical Phisics, Chinese Academy of Sciences (China)
- Year and Date
  2013-06-28
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] マイクロ化学プロセスを利用したコンドロイチン硫酸オリゴ糖の大量調製方法の確立2013
- Author(s)
  山田修平、松嶋景一郎、浦晴雄、宮本宣之、菅原一幸
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Novel Class of Tetrahydropyridine-fused Pyrazoles, Isoxazolines, and HS-Mimetic Small Molecules as Anti-cancer Agents2013
- Author(s)
  Rangappa KS, Basappa, Mantelingu K, Sadashiva MP, Feng Li, Gautam Sethi, Kazuyuki Sugahara
- Organizer
  The 14th tetrahedron symposium
- Place of Presentation
  Hilton Vienna (Austria)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Wobble chondroitin sulfate oligosaccharide motifs and mass production of oligosaccharides2013
- Author(s)
  Kazuyuki Sugahara
- Organizer
  The 21st Symposium on Glycosaminoglycans
- Place of Presentation
  Villa Vigoni (Italy)
- Year and Date
  2013-09-19
- Invited
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] 第59回日本薬学会東海支部総会2013
- Author(s)
  山田修平、松嶋景一郎、浦晴雄、宮本宣之、菅原一幸
- Organizer
  第59回日本薬学会東海支部総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Mass Preparation of Oligosaccharides with Intestinal Absorption Capacity by Hydrolysis of Chondroitin Sulfate Polysaccharides with Subcritical Water Microreaction System2013
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, and Nobuyuki Miyamoto
- Organizer
  13th International Conference of FFC and 1st International Symposium of Academic Society for Functional Foods and Bioactive Compounds
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Development of novel monoclonal antibodies against chondroitin sulfate, and their application to glycobiology and glycopathology2013
- Author(s)
  Peraphan Pothacharoen, Duriya Fongmoon, Shuji Mizumoto, Kazuyuki Sugahara, Prachya Kongtawlert
- Organizer
  The 5th annual conference for Asian Communications of Glycobiology and Glycotechnology
- Place of Presentation
  Khon Kaen University (Thailand.)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] ヒアルロニダーゼはコンドロイチン4-硫酸に対しヒアルロン酸と同程度の強い加水分解活性をもつ2013
- Author(s)
  山田修平、本田智子、金岩知之、水本秀二、菅原一幸
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Mass preparation of chondroitin sulfate oligosaccharides by hydrolysis with subcritical water2013
- Author(s)
  山田修平、松嶋景一郎、浦晴雄、宮本宣之、菅原一幸
- Organizer
  第３２回日本糖質学会年会
- Place of Presentation
  大阪国際交流センター(大阪)
- Data Source
  KAKENHI-PUBLICLY-24110501
[Presentation] ヒトとマウスにおけるコンドロイチン硫酸加水分解酵素の基質特異性の違いに関わるアミノ酸残基の同定2013
- Author(s)
  山田修平、金岩知之、宮崎杏、古川諒、水本秀二、菅原一幸
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] マイクロ化学プロセスによる新規糖鎖食品の開発2013
- Author(s)
  松嶋景一郎、浦晴雄、宮本宣之、菅原一幸、山田修平、水本秀二
- Organizer
  北海道立総合研究機構　技術移転フォーラム2013
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] RAGEは癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する2012
- Author(s)
  水本秀二,高橋潤, 菅原一幸
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島市民文化ホール、(口頭発表)and Kazuyuki Sugahara、
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] グルクロン酸転移酵素-Iの変異によって引き起こされる新規ラーセン様症候群2012
- Author(s)
  水本秀二, Sevjidmaa Baasanjav, Lihadh Al-Gazali, 橋口太志, Bjoern Fischer, Denise Horn, Dominik Seelow, Bassam R.Ali, Samir A.A.Aziz, Ruth Langer, Ahmed A.H.Saleh, Christian Becker, Gudrun Nurnberg, Vincent Cantagrel, Joseph G.Gleeson, Delphine Gomez, Jean-Baptiste Michel, Sigmar Stricker, Tom H.Lindner, Peter Nurnberg, Stefan Mundlos, Katrin Hoffmann, 菅原一幸
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] サメヒレ軟骨コンドロイチン硫酸由来の新規な六糖配列の単離2012
- Author(s)
  水本秀二,村越早織,Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, 福井成行, Prachya Kongtawelert, 山田修平, 菅原一幸
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場およびマリンメッセ福岡、(ポスター発表)
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] コンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の酵素活性に必要なアミノ酸残基の同定2012
- Author(s)
  山田修平、金岩知之、宮崎杏、水本秀二、菅原一幸
- Organizer
  第５８回日本薬学会東海支部総会・大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] がんの肺転移に関わるグリコサミノグリカン受容体(RAGE)の同定2012
- Author(s)
  高橋潤, 水本秀二, 菅原一幸
- Organizer
  第49回日本生化学会北海道支部例会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-07-20
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Development of a sulfated glycosaminoglycan array and analysis of molecular interactions between glycosaminoglycans and growth fractors/antibodies2012
- Author(s)
  Wataru Takada, Masao Fukushima, Prachya Kongtawelert, and ○Kazuyuki Sugahara
- Organizer
  The 15th Gordon Research Conference on Proteoglycans
- Place of Presentation
  Proctor Academy(米国)
- Year and Date
  2012-06-09
- Data Source
  KAKENHI-PUBLICLY-24110501
[Presentation] Receptor for Advanced Glycation End products (RAGE)は肺転移に関わるがん細胞表面のグリコサミノグリカン受容体として機能する2012
- Author(s)
  ○高橋潤, 水本秀二 , 菅原一幸
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] GAG signals involved in pulmonary metastasis of tumor cells2012
- Author(s)
  Kazuyuki Sugahara
- Organizer
  The 20th Symposium on glycosaminoglycans
- Place of Presentation
  Villa Vigoni (Italy)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] コンドロイチン硫酸特異的加水分解酵素の発現組織の解析およびその機能の研究2012
- Author(s)
  古川諒、金岩知之、宮崎杏、菅原一幸、山田修平
- Organizer
  第49回日本生化学会北海道支部例会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] がん細胞の肺転移に関わる硫酸化グリコサミノグリカンの受容体の同定2012
- Author(s)
  高橋潤, 水本秀二, 菅原一幸
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Receptor for Advanced Glycation End-products (RAGE) functions as areceptor for glycosaminoglycans involved in pulmonary metastasis2012
- Author(s)
  Shuji MIZUMOTO, Jun TAKAHASHI,Kazuyuki SUGAHARA
- Organizer
  The 10th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ.、(Poster& Short talk)
- Year and Date
  2012-10-03
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] コンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の酵素活性に必要なアミノ酸残基の同定2012
- Author(s)
  金岩知之、宮崎杏、水本秀二、菅原一幸、山田修平
- Organizer
  第49回日本生化学会北海道支部例会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Receptor for Advanced Glycation End-products (RAGE) Functions as a Receptor for Pulmonary Metastasis Mediated by Sulfated Glycosaminoglycans2012
- Author(s)
  Kazuyuki Sugahara
- Organizer
  2nd International Anatomical Sciences and Cell Biology Conference/36th Annual Conference of the Anatomy Association of Thailand
- Place of Presentation
  Chiang Mai Univ. (Thailand)
- Invited
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] ○高橋潤, 水本秀二 , 菅原一幸2012
- Author(s)
  ○高橋潤, 水本秀二 , 菅原一幸
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] ヒアルロニダーゼの本来の基質はヒアルロン酸ではなくコンドロイチン硫酸2012
- Author(s)
  山田修平、本田智子、金岩知之、水本秀二、菅原一幸
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Shrimp head heparan sulfate with unique structure and function2012
- Author(s)
  Yoshiki Hama, Chen Jiancheng, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Eunmi Kim, Takashi Kimura, Kazuyuki Sugahara, Shuhei Yamada
- Organizer
  The IGP International Symposium 2012
- Place of Presentation
  Hokkaido Univ. (Sapporo)
- Year and Date
  2012-03-02
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Receptor for Advanced Glycation End Products (RAGE)は癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する2012
- Author(s)
  水本秀二, 高橋潤, 菅原一幸
- Organizer
  日本薬学会北海道支部第138回例会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2012-06-16
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] サメヒレ軟骨コンドロイチン硫酸由来の新規な六糖配列の単離2012
- Author(s)
  ◯水本秀二, 村越早織, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, 福井成行, Prachya Kongtawelert, 山田修平, 菅原一幸
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡市)
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PUBLICLY-24110501
[Presentation] Characterization of a receptor for glycosaminoglycans that mediate experimental lung metastasis2012
- Author(s)
  Kazuyuki Sugahara
- Organizer
  The 15th Gordon Research Conference on Proteoglycans
- Place of Presentation
  Proctor Academy (USA)
- Year and Date
  2012-07-10
- Invited
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] コンドロイチン硫酸に特異的な加水分解酵素に関する研究2012
- Author(s)
  山田修平，金岩知之，宮崎杏，古川諒，水本秀二，菅原一幸
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences involved in brain development2012
- Author(s)
  ○Shuji Mizumoto, Saori Murakoshi, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fukui, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
- Organizer
  2012年度　包括型脳科学研究推進支援ネットワーク・夏のワークショップ
- Place of Presentation
  仙台国際センター(仙台市)
- Year and Date
  2012-07-26
- Data Source
  KAKENHI-PUBLICLY-24110501
[Presentation] 硫酸化GAGマイクロアレイの開発およびGAGと成長因子/抗体との相互作用解析2012
- Author(s)
  ○高田渉，福島雅夫, Peraphan Pothacharoen, Prachya Kongtawelert, 菅原一幸
- Organizer
  第３１回日本糖質学会年会
- Place of Presentation
  鹿児島市民ホール(鹿児島市)
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PUBLICLY-24110501
[Presentation] ヒトヒアルロニダーゼはコンドロイチン硫酸Aをヒアルロン酸と同程度の速度で加水分解する2012
- Author(s)
  本田智子、金岩知之、水本秀二、菅原一幸、山田修平
- Organizer
  第49回日本生化学会北海道支部例会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences involved in brain development2012
- Author(s)
  Shuji Mizumoto, Saori Murakoshi,Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fukui, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
- Organizer
  2012年度包括型脳科学研究推進支援ネットワーク・夏のワークショップ
- Place of Presentation
  仙台国際センター、(ポスター発表)
- Year and Date
  2012-07-26
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Receptor for Advanced Glycation End Products (RAGE)は癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する2012
- Author(s)
  水本秀二,高橋潤,菅原一幸
- Organizer
  日本薬学会北海道支部第138回例会
- Place of Presentation
  札幌コンベンションセンター、(口頭発表)
- Year and Date
  2012-06-16
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] ヒトヒアルロニダーゼのコンドロイチン４硫酸に対する高い加水分解活性2012
- Author(s)
  本田智子、金岩知之、水本秀二、菅原一幸、山田修平
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Receptor for Advanced Glycation End-products (RAGE) functions as a receptor for glycosaminoglycans involved in pulmonary metastasis2012
- Author(s)
  Shuji Mizumoto, Jun Takahashi, Kazuyuki Sugahara
- Organizer
  The 10th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ. (Sapporo)
- Year and Date
  2012-10-03
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] グルクロン酸転移酵素-I の変異によって引き起こされる新規ラーセン様症候群2012
- Author(s)
  水本秀二, Sevjidmaa Baasanjav, Lihadh Al-Gazali, 橋口太志, Bjoern Fischer, Denise Horn, Dominik Seelow, Bassam R. Ali, Samir A.A. Aziz, Ruth Langer, Ahmed A.H. Saleh, Christian Becker, Gudrun Nürnberg, Vincent Cantagrel, Joseph G. Gleeson, Delphine Gomez, Jean-Baptiste Michel, Sigmar Stricker, Tom H. Lindner, Peter Nürnberg, Stefan Mundlos, Katrin Hoffmann, 菅原一幸
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] ユニークな構造と機能をもつエビ頭部に由来するヘパラン硫酸2012
- Author(s)
  羽磨紀城, 陳建成, Ajaya Kumar Shetty, 小林孝成, 織田浩司, 清木興介, Eunmi Kim, 木村享史, 菅原一幸, 山田修平
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] RAGEは癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する2012
- Author(s)
  水本秀二, 高橋潤, 菅原一幸
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島市民ホール(鹿児島市)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] 「Shrimp head heparan sulfate with unique structure and function2012
- Author(s)
  Yoshiki Hama, Chen Jiancheng, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Eunmi Kim, Takashi Kimura, Kazuyuki Sugahara, Shuhei Yamada
- Organizer
  The IGP International Symposium 2012
- Place of Presentation
  Sapporo
- Year and Date
  2012-03-02
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] 糖鎖生物学による癌の肺転移の分子メカニズムの解明抗癌剤開発に向けての洞察2012
- Author(s)
  菅原一幸
- Organizer
  第16回未来創薬・医療イノベーションセミナー(国際会議)
- Place of Presentation
  北海道大学 (札幌市)
- Year and Date
  2012-07-31
- Invited
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] コンドロイチン硫酸特異的加水分解酵素の発現組織の解析および精巣における機能の研究2012
- Author(s)
  古川諒、金岩知之、宮崎杏、菅原一幸、山田修平
- Organizer
  日本薬学会北海道支部137例会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Receptor for Advanced Glycation End products (RAGE)は肺転移に関わるがん細胞表面のグリコサミノグリカン受容体として機能する2012
- Author(s)
  高橋潤, 水本秀二, 菅原一幸
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡市)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] グルクロン酸転移酵素-Iの変異によって引き起こされる新規ラーセン様症候群2012
- Author(s)
  ◯水本秀二, Baasanjav S, Al-Gazali L, 橋口太志, Mundlos S, Hoffmann K, 菅原一幸 et al.
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Loss-of-function mutation of glucuronyltransferase-I causes Larsen-like syndrome2011
- Author(s)
  Baasanjav S, Al-Gazali L, Hashiguchi T, ○Mizumoto S, Sugahara K, Mundlos S, Hoffmann K. et al.
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  Q Station (Australia)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] エビ頭部に由来するヘパラン硫酸の構造と生物活性2011
- Author(s)
  羽磨紀城、陳建成、Ajaya Kumar Shetty、小林孝成、織田浩司、清木興介、Eunmi Kim、木村享史、菅原一幸、山田修平
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール(新潟県)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] コンドロイチン硫酸/デルマタン硫酸の生合成に関わる酵素の欠損による骨・皮膚疾患2011
- Author(s)
  水本秀二,三宅紀子,古庄知己, Mirjam H.H. van Roij, Beyhan Tuysuz,Stefan Mundlos, Stephen P. Robertson, 山田修平, 松本直通, 菅原一幸
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール、(口頭発表)
- Year and Date
  2011-07-11
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E構造の発現低下による転移抑制2011
- Author(s)
  水本秀二、渡邊基夫、山田修平、菅原一幸
- Organizer
  日本薬学会北海道支部第136回例会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] エビ頭部由来ヘパラン硫酸の構造と機能の研究2011
- Author(s)
  陳建成、羽磨紀城、Ajaya Kumar Shetty、小林孝成、織田浩司、清木興介、木村享史、高橋尚徳、左一八、鈴木隆、鈴木康夫、〇山田修平、菅原一幸
- Organizer
  日本薬学会北海道支部第136回例会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] コンドロイチン硫酸/デルマタン硫酸の生合成に関わる酵素の欠損による骨・皮膚疾患2011
- Author(s)
  ○水本秀二, 三宅紀子, 古庄知己, Mirjam H.H. van Roij, Beyhan Tuysuz, Stefan Mundlos, Stephen P. Robertson, 山田修平, 松本直通, 菅原一幸
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール(新潟県)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Involvement of chondroitin sulphate E-type structure in the experimental metastasis of the Lewis lung carcinoma cell line2011
- Author(s)
  K.Sugahara
- Organizer
  The 3rd FEBS-MPST Advanced Lecture Course on Matrix Pathobiology, Signaling and Molecular Targets (FEBS-MPST2011)
- Place of Presentation
  Spetses Hotel and Anargyrios College (Greece)(招待講演)
- Year and Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] エビ頭部に由来するヘパラン硫酸の構造と生物活性2011
- Author(s)
  羽磨紀城, 陳建成, Ajaya Kumar Shetty, 小林孝成, 織田浩司, 清木興介, Eunmi Kim, 木村享史, 菅原一幸, 山田修平
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール(長岡市)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Involvement of chondroitin sulphate E-type structure in the experimental metastasis of the Lewis lung carcinoma cell line2011
- Author(s)
  Kazuyuki Sugahara
- Organizer
  The 3rd FEBS-MPST Advanced Lecture Course on Matrix Pathobiology, Signaling and Molecular Targets
- Place of Presentation
  Spetses Hotel and the Anargyrios College (Greece)
- Year and Date
  2011-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Studies on novel mammalian endo-type chondroitin sulfate hydrolases2011
- Author(s)
  T. Kaneiwa, A. Miyazaki, S. Mizumoto, K. Sugahara, S. Yamada
- Organizer
  The 3rd FEBS-MPST Advanced Lecture Course on Matrix Pathobiology, Signaling andMolecular Targets (FEBS-MPST2011).
- Place of Presentation
  Spetses, Greece
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Chondroitin sulfate E type structure at tumor cell surface is involved in the experimental metastasis of mouse tumor cell lines2011
- Author(s)
  菅原一幸
- Organizer
  9th International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules
- Place of Presentation
  Trivandrum, Kerala, India
- Year and Date
  2011-01-28
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Mouse hyaluronidase-4 : Identification of a chondroitin sulfate-specific hydrolase with distinct specificity from human hyaluronidase-42011
- Author(s)
  S. Yamada, A. Miyazaki, T. Kaneiwa, S. Mizumoto, and K. Sugahara
- Organizer
  The 31st Naito Conference. Glycan Expression and Regulation [II]: Metabolites, Stress Response, Microdomains, and Beyond.
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] コンドロイチン硫酸E構造の発現調節によるルイス肺癌細胞の転移抑制2011
- Author(s)
  水本秀二、渡邊基夫、山田修平、菅原一幸
- Organizer
  日本薬学会北海道支部第136例会
- Place of Presentation
  札幌コンベンションセンター、(口頭発表)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] A deficiency of glycosaminoglycans causes cardiac and joint disorders2011
- Author(s)
  Baasanjav S, Al-Gazali L, Hashiguchi T, ○Mizumoto S, Sugahara K, Mundlos S, Hoffmann K. et al.
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E構造の発現低下による転移抑制2011
- Author(s)
  渡邊基夫、水本秀二、山田修平、菅原一幸
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール(新潟県)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Analysis of the expression pattern of dermatan sulfate epimerase-2, which is involved in the bipolar disorder, in the mouse brain during postnatal development2011
- Author(s)
  Chizuru Akatsu, Shuji Mizumoto, Tomoyuki Kaneiwa, Marco Maccarana, Anders Malmström, Shuhei Yamada, ○Kazuyuki Sugahara
- Organizer
  The 9th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ. (Sapporo)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] A deficiency of glycosaminoglycans causes cardiac and joint disorders2011
- Author(s)
  Sevjidmaa Baasanjav, Lihadh Al-Gazali, Taishi Hashiguchi, Shuji Mizumoto, Bjoern Fischer, Denise Horn, Dominik Seelow, Bassam R.Ali, Samir A.A.Aziz, Ruth Langer, Ahmed A.H.Saleh, Christian Becker, Gudrun Nurnberg, Vincent Cantagrel, Joseph G.Gleeson, Delphine Gomez, Jean-Baptiste Michel, Sigmar Stricker, Tom H.Lindner, Peter Nurnberg, Kazuyuki Sugahara, Stefan Mundlos, Katrin Hoffmann
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-0-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in a-Thrombomodulin from Human Urine2011
- Author(s)
  T.Hashiguchi, S.Mizumoto, Y.Nishimura, J.Tamura, 〇S.Yamada, K.Sugahara
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  QSTATION (Australia)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Characterization of a receptor for glycosaminoglycans that mediate experimental lung metastasis2011
- Author(s)
  K.Sugahara, S.Mizumoto, J.Takahashi
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  QSTATION (Australia)(招待講演)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Loss-of-function mutation of glucuronyltransferase-I causes Larsen-like syndrome2011
- Author(s)
  S.Baasanjav, L.Al-Gazali, T.Hashiguchi, 〇S.Mizumoto, B.Fischer, D.Horn, D.Seelow, B.R.Ali, S.A.A.Aziz, R.Langer, A.A.H.Saleh, C.Becker, G.Nurnberg, V.Cantagrel, J.G.Gleeson, D.Gomez, J.-B.Michel, S.Stricker, T.H.Lindner, P.Nurnberg, K.Sugahara, S.Mundlos, K.Hoffmann
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  QSTATION (Australia)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Loss-of-function mutation of glucuronyltransferase-I causes Larsen-like syndrome2011
- Author(s)
  S. Baasanjav, L. Al-Gazali, T. Hashiguchi, ○S. Mizumoto, B. Fischer, D. Horn, D. Seelow, B. R. Ali, S.A.A. Aziz, R. Langer, A. A.H. Saleh, C. Becker, G. Nürnberg, V. Cantagrel, J. G. Gleeson, D. Gomez, J.-B. Michel, S. Stricker, T. H. Lindner, P. Nürnberg, K. Sugahara, S. Mundlos, K. Hoffmann
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  Q STATION (Australia)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] 「Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in ?-Thrombomodulin from Human Urine」2011
- Author(s)
  T. Hashiguchi, S. Mizumoto, Y. Nishimura, J. Tamura, S. Yamada, K. Sugahara
- Organizer
  7th International Conference onProteoglycans
- Place of Presentation
  Sydney, Australia
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E 構造の発現低下による転移抑制2011
- Author(s)
  水本秀二, 渡邊基夫, 山田修平, 菅原一幸
- Organizer
  日本薬学会北海道支部第136回例会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] A deficiency of glycosaminoglycans causes cardiac and joint disorders2011
- Author(s)
  Sevjidmaa Baasanjav, Lihadh Al-Gazali, Taishi Hashiguchi, ○ Shuji Mizumoto, Bjoern Fischer, Denise Horn, Dominik Seelow, Bassam R. Ali, Samir A.A. Aziz, Ruth Langer, Ahmed A.H. Saleh, Christian Becker, Gudrun Nürnberg, Vincent Cantagrel, Joseph G. Gleeson, Delphine Gomez, Jean-Baptiste Michel, Sigmar Stricker, Tom H. Lindner, Peter Nürnberg, Kazuyuki Sugahara, Stefan Mundlos, Katrin Hoffmann
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in a-Thrombomodulin from Human Urine2011
- Author(s)
  T. Hashiguchi, S. Mizumoto, Y. Nishimura, J. Tamura, ○S. Yamada, K. Sugahara
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  Q STATION (Australia)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E 構造の発現低下による転移抑制2011
- Author(s)
  渡邊基夫, 水本秀二, 山田修平, ○菅原一幸
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール(長岡市)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Loss-of-function mutations of dermatan 4-O-sulfotransferase-1 cause a new type of Ehlers-Danlos syndrome2011
- Author(s)
  Shuji Mizumoto, Noriko Miyake, Tomoki Kosho, Shuhei Yamada, Kazuyuki Sugahara, and Naomichi Matsumoto
- Organizer
  The 9th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ、(Poster)
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Determination of amino acid sequences in hyaluronidase-4 responsible for the substrate recognition2011
- Author(s)
  T. Kaneiwa, A. Miyazaki, S. Mizumoto, K. Sugahara, and S. Yamada
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  Sydney, Australia
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Loss-of-function mutations of dermatan 4-O-sulfotransferase-1 cause a new type of Ehlers-Danlos syndrome2011
- Author(s)
  ◯Shuji Mizumoto, Noriko Miyake, Tomoki Kosho, Shuhei Yamada, Kazuyuki Sugahara, and Naomichi Matsumoto
- Organizer
  The 9th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ. (Sapporo)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] エビ頭部由来へパラン硫酸の構造と機能の研究2011
- Author(s)
  陳建成, 羽磨紀城, Ajaya Kumar Shetty, 小林孝成, 織田浩司, 清木興介, 木村享史, 高橋尚徳, 左一八, 鈴木隆, 鈴木康夫, ○山田修平, 菅原一幸
- Organizer
  日本薬学会北海道支部第136回例会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Involvement of the Hepatocyte Growth Factor Signaling Pathway in the Neuritogenic Activity of Chondroitin Sulfate Derived from Ray Fish Cartilage2010
- Author(s)
  T. Hashiguchi, T. Kobayashi, D. Fongmoon, A. K. Shetty, S. Mizumoto, N. Miyamoto, T. Nakamura, S. Yamada, and K. Sugahara
- Organizer
  The 25th International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Chiba
- Year and Date
  2010-08-03
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Glycobiology meets Computer Science : Structure of Pleiotrophin- and Hepatocyte Growth Factor-binding Sulfated Hexasaccharide Determined by Biochemical and Computational Approaches2010
- Author(s)
  Kazuyuki Sugahara
- Organizer
  The 8^<th> International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Sappbro
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Glycobiology meets Computer Science: Structure of Pleiotrophin-and Hepatocyte Growth Factor-binding Sulfated Hexasaccharide Determined by Biochemical and Computational Approaches.2010
- Author(s)
  K.Sugahara, F.Li, C.D.Nandini, T.Hattori, X.Bao, D.Murayama, T.Nakamura, N.Fukushima
- Organizer
  The 25^<th> International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Chiba
- Year and Date
  2010-08-02
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Structural characterization of heparan sulfate in the Extl3 knockout mice and the pancreatic β-cell specific Extl3 knockout mice2010
- Author(s)
  T. Kaneiwa, S. Yamada, K. Sugahara, I. Takahashi, N. Noguchi, K. Nata, H. Okamoto, A. Sugawara
- Organizer
  The 25th International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Chiba
- Year and Date
  2010-08-02
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Identification of a chondroitin sulfate-specific novel hydrolase in human2010
- Author(s)
  T. Kaneiwa, S. Mizumoto, K. Sugahara, S. Yamada
- Organizer
  The 25th International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Chiba
- Year and Date
  2010-08-05
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] The E-type structure of chondroitin sulfate on tumor cell surfaces is involved in lung and liver metastases.2010
- Author(s)
  Kazuyuki Sugahara, Fuchuan Li, Sengottuvelan Murugan, Basappa, Taishi Hashiguchi, Shuji Mizumoto, Shuhei Yamada, Kayoko Oguri, Minoru Okayama, Kazuki N.Sugahara, Chun Man Lee, Masayuki Miyasaka, Gerdy B.ten Dam, Toin H.van Kuppevelt
- Organizer
  Asian Communications of Glycobiology and Glycotechnology (ACGG)
- Place of Presentation
  Taipei
- Year and Date
  2010-10-27
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Demonstration of chondroitin sulfate-specific hydrolytic activity in human hyaluronidase-42010
- Author(s)
  T. Kaneiwa, S. Mizumoto, K. Sugahara, S. Yamada
- Organizer
  The 8th International Conference on Hyaluronan Sciences
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Glycobiology meets Computer Science : Structure of Pleiotrophin- and Hepatocyte Growth Factor-binding Sulfated Hexasaccharide Determined by Biochemical and Computational Approaches.2010
- Author(s)
  Kazuyuki Sugahara
- Organizer
  The 25^<th> International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Chiba
- Year and Date
  2010-08-02
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Identification of a novel chondroitin sulfate hydrolase applicable to neuronal regenerative therapy2010
- Author(s)
  Trivandrum, Kerala, IndiaT. Kaneiwa, S. Mizumoto, K. Sugahara, S. Yamada
- Organizer
  The 8th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Sapporo
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] The E-type structure of chondroitin sulfate on tumor cell surfaces is involved in lung and liver metastases2010
- Author(s)
  Kazuyuki Sugahara
- Organizer
  Asian Communications of Glycobiology and Glycotechnology (ACGG)
- Place of Presentation
  Taipei(台湾)
- Year and Date
  2010-10-27
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Identification and characterization of a novel chondroitin hydrolase in Caenorhabditis elegans2009
- Author(s)
  Tomoyuki Kaneiwa, Shuhei Yamada, Shuji Mizumoto, Adriana M. Montano, Muneyoshi Otori, Shohei Mitani, and Kazuyuki Sugahara
- Organizer
  6th International Conference on Proteoglycan
- Place of Presentation
  Aix-les-Bains, France
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Structure and biological activities of heparin-like glycosaminoglycan from shrimp heads2009
- Author(s)
  Jiancheng Chen, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Shuhei Yamada, and Kazuyuki Sugahara
- Organizer
  2nd Symposium on Structural Analysis of Biological Macromolecules & 7th Japan-Korea Bilateral Symposium on Biological NMR
- Place of Presentation
  Sapporo
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Cell surface chondroitin sulfate E type structure of mouse tumor cell lines is involved in the experimental metastasis to the lung and liver.2009
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Sengottuvelan Murugan, Fuchuan Li, Basappa, Taishi Hashiguchi, Shuji Mizumoto, Kayoko Oguri, Minoru Okayama, Kazuki N. Sugahara, Chun Man Lee, Masayuki Miyasaka, Gerdy B.ten Dam, Toin H.van Kuppevelt
- Organizer
  6th international Conference on Proteoglycan
- Place of Presentation
  Aix-les-Bains, France
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Identification and characterization of a novel chondroitin hydrolase in Caenorhabditis elegans2009
- Author(s)
  Tomoyuki Kaneiwa, Shuhei Yamada, Shuji Mizumoto, Adriana M. Montano, Shohei Mitani, and Kazuyuki Sugahara
- Organizer
  2nd Symposium on Structural Analysis of Biological Macromolecules & 7th Japan-Korea Bilateral Symposium on Biological NMR
- Place of Presentation
  Sapporo
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Identification of Human Hyaluronidase-4 as a Novel Chondroitin Sulfate Hydrolase That Preferentially Cleaves the Specific Linkage in a Highly Sulfated Sequence2009
- Author(s)
  Shuhei Yamada, Tomoyuki Kaneiwa, Shuji Mizumoto, and Kazuyuki Sugahara
- Organizer
  6th International Conference on Proteoglycan
- Place of Presentation
  Aix-les-Bains, France
- Year and Date
  2009-09-15
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] 組替え体ヒトヒアルロニダーゼ-4の基質特異性の研究2008
- Author(s)
  山田修平, 桝本典子, 檜垣鮎美, 宮田かおる, 金岩知之, 水本秀二, S. S. Deepa, 北川裕之, 菅原一幸
- Organizer
  第28回日本糖質学会年会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] コンドロイチン4-O-硫酸基転移酵素-1のゼブラフィッシュ胚発生過程における機能の解析2008
- Author(s)
  安永大輝, 水本秀二, 小林直樹, 三上雅久, 三宅歩, 伊藤信行, 菅原一幸, 北川裕之
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] C6ST-1過剰発現マウスを用いた脳におけるコンドロイチン硫酸鎖の機能解析2008
- Author(s)
  宮田真路, 迫田直樹, 三上雅久, 菅原一幸, 多屋長治, 北川裕之
- Organizer
  第28回日本糖質学会年会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] C. elegansを用いた硫酸化修飾関連遺伝子の器官形成における役割と硫酸供与体PAPSの合成・輸送機構の解析2008
- Author(s)
  出嶋克史, 瀬古玲, 山下克子, 泉川友美, 北川裕之, 菅原一幸, 野村和子, 水口惣平, 村田大輔, 安藤恵子, 三谷昌平, 野村一也
- Organizer
  第31回日本分子生物学会年会第81回日本生化学学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] 動物界に必須の多糖鎖グリコサミノグリカン2008
- Author(s)
  菅原一幸
- Organizer
  日本薬学会北海道支部第130回例会
- Place of Presentation
  札幌コンベンションセンター(札幌)
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] ゼブラフィッシュ胚発生過程におけるコンドロイチン4-O-硫酸基転移酵素-1の機能2008
- Author(s)
  安永大輝, 水本秀二, 小林直樹, 三上雅久, 三宅歩, 伊藤信行, 菅原一幸, 北川裕之
- Organizer
  第28回日本糖質学会年会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] Identification of Chondroitin Sulfate Glucuronyltransferase as Chondroitin Synthase-3 Involved in Chondroitin Polymerization : CHONDROITIN POLYMERIZATION IS ACHIEVED BY MULTIPLE ENZYME COMPLEXES CONSISTING OF CHONDROITIN SYNTHASE FAMILY MEMBERS2008
- Author(s)
  Izumikawa, T., Koike, T., Shiozawa, S., Sugahara, K., Tamura, J., Kitagawa, H.
- Organizer
  XXIV International Carbohydrate Symposium
- Place of Presentation
  Oslo
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] 4種のコンドロイチン合成酵素ファミリーの酵素複合体によるコンドロイチン鎖の合成機構2008
- Author(s)
  小池敏靖, 泉川友美, 塩澤章子, 菅原一幸, 田村純一, 北川裕之
- Organizer
  第28回日本糖質学会年会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] コンドロイチン合成酵素複合体によるコンドロイチン鎖の合成機構2008
- Author(s)
  泉川友美, 小池敏靖, 塩澤章子, 奥浦由佳, 田村純一, 菅原一幸, 北川裕之
- Organizer
  第9回関西グライコサイエンスフォーラム
- Place of Presentation
  大阪
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] Determination of iduronic acid and glucuronic acid in sulfated chondroitin/dermatan hybrid chains by 1H-nuclear magnetic resonance spectroscopy2007
- Author(s)
  Fuchuan Li & Shuhei Yamada & Makiko Sugiura & Kazuyuki Sugahara
- Organizer
  The 127th Japanease Pharmaceutical Symposium
- Place of Presentation
  Toyama
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] コンドロイチンGalNAc 転移酵素-1 および-2 のコンドロイチン硫酸鎖生合成への関与2007
- Author(s)
  小池敏靖, 宇山徹, 迫田直樹, 奥浦由佳, 泉川友美, 菅原一幸, 北川裕之
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] Two Related but Distinct Chondroitin Sulfate Mimetope Octasaccharide Sequences of Monoclonal Antibody WF6, Which Recognizes a Human Ovarian Tumor Marker.2007
- Author(s)
  Peraphan Pothacharoen, Kittiwan Kalayanamitra, Sarama S. Deepa, Shigeyuki Fukui, Tomohide Hattori, Nobuhiro Fukushima, Timothy Hardingham, Prachya Kongtawelert, and Kazuyuki Sugahara
- Organizer
  The 27^<th> Sapproro Cancer Seminar International Symposium
- Place of Presentation
  Sapporo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Functions of chondroitin sulfate/dermatan sulfate in the brain development: Critical roles of "E" and/or "iE" disaccharide units recognized by a single chain antibody GD3G72007
- Author(s)
  A. Purushothaman, Junko Fukuda, Shuji Mizumoto, GB. ten Dam, T. H. van Kuppevelt, Hiroshi Kitagawa, Tadahisa Mikami, Kazuyuki Sugahara
- Organizer
  Glycobiology and Sphingobiology 2007 (GS2007)-Hakomori Commemorative Forum-
- Place of Presentation
  Tokushima
- Year and Date
  2007-02-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Glycobiology of Proteoglycan Signaling in Brain Development2007
- Author(s)
  Sugahara K
- Organizer
  FEBS Advanced Lecture Course, "Matrix Pathobiology, Signaling and Molecular Targets"
- Place of Presentation
  Patras, Greece
- Year and Date
  2007-05-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] コンドロイチン硫酸の硫酸化を担う硫酸基転移酵素による軟骨分化制御2007
- Author(s)
  三上雅久, 森田知子, 竹中裕美, 安永大輝, 薮田ゆみ, 菅原一幸, 北川裕之
- Organizer
  第57回日本薬学会近畿支部大会
- Place of Presentation
  高槻
- Year and Date
  2007-10-27
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] Determination of iduronic acid and glucuronic acid in sulfated chondroitin/dermatan hybrid chains by 1H-nuclear magnetic resonance spectroscopy2007
- Author(s)
  Fuchuan Li & Shuhei Yamada & Makiko Sugiura & Kazuyuki Sugahara
- Organizer
  BMB2007
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Expression profies of chondroitin sulfate sulfotransferases in chondrogenic ATDC5 cells2007
- Author(s)
  森田知子, 竹中裕美, 安永大揮, 薮田ゆみ, 記村真衣, 三上雅久, 菅原一幸, 北川裕之
- Organizer
  第27回日本糖質学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] The epitope structure recognized by anti-chondroitin sulfate antibodies2007
- Author(s)
  Kazuyuki Sugahara, Sarama S. Deepa, Kittiwan Kalayanamitra, Peraphan Pothacharoen, Prachya Kongtawelert, Yumi Ito, Tadahisa M Ikami, Basappa, Shuhei Yamada, Shigeyuki Fukui, Tim Hardingham, Veronique Blanchard, Franck Chevalier, Anne Imberty, Bas R. Leeflang, Johannis P. Kamerling, Tomohide Hattori, Nobuhiro Hukushima
- Organizer
  The 27^<th> Japanease Carbohydrate Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2007-08-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] ブタ胎仔脳とサメ肝臓由来のコンドロイチン/デルマタン硫酸ハイブリッド鎖の神経突起伸長促進活性:プレイオトロフィンンとHGFシグナル伝達経路の関与2007
- Author(s)
  菅原一幸
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Expression of rib-1, a Caenorhabditis elegans Homolog of the Human Tumor Suppressor EXT Genes, Is Indispensable for Heparan Sulfate Synthesis and Embryonic Morphogenesis.2007
- Author(s)
  Kitagawa H., Izumikawa T., Mizuguchi S., Dejima K., Nomura K. H., Egusa F., Taniguchi F., Tamura J., Gengyo-Ando K., Mitani S., Nomura K., Sugahara K.
- Organizer
  第19回複合糖質国際シンポジウム(Glyco 19)
- Place of Presentation
  ケアンズ
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] モデル生物C. elegans を用いたヘパラン硫酸の生体内機能解析2007
- Author(s)
  水口惣平, 野村和子, 出嶋克史, 泉川友美, 江草徳幸, 谷口史恭, 田村純一, 安藤恵子, 三谷昌平, 北川裕之, 菅原一幸, 野村一也
- Organizer
  第27回日本糖質学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] Glycobiology of Proteoglycan Signaling in Brain Development.2007
- Author(s)
  Kazuyuki Sugahara
- Organizer
  FEBS Advanced Lecture Course, "Matrix Pathobiology, Signaling and Molecular Targets"
- Place of Presentation
  Patras, Greece
- Year and Date
  2007-05-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Two Related but Distinct Chondroitin Sulfate Mimetope Octasaccharide Sequences of Monoclonal Antibody WF6, Which Recognizes a Human Ovarian Tumor Marker.2007
- Author(s)
  Kazuyuki Sugahara
- Organizer
  The 27th Sapporo Cancer Seminar International Symposium
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Two Related but Distinct Chondroitin Sulfate Mimetope Octasaccharide Sequences Recognized by Monoclonal Antibody WF6.2007
- Author(s)
  K. Sugahara, P. Pothacharoen, K. Kalayanamitra, S.S. Deepa, S. Fukui, T. Hattori, N. Fukushima, T. Hardingham, and P. Kongtawelert
- Organizer
  Glycol9 (XLX International Symposium on Glycoconjugates)
- Place of Presentation
  Cairns
- Year and Date
  2007-07-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Structural determination of novel sulfated octasaccharides isolated from chondroitin sulfate of shark cartilage and their application for characterizing monoclonal antibody epitopes2007
- Author(s)
  Sarama S. Deepa, Shuhei Yamada, Shigeyuki Fukui, Kazuyuki Sugahara
- Organizer
  The 27^<th> Japanease Carbohydrate Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2007-08-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] 抗コンドロイチン硫酸抗体のエピトープ構造2007
- Author(s)
  菅原一幸
- Organizer
  第27回日本糖質学会年会
- Place of Presentation
  福岡
- Year and Date
  2007-08-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Wnt-3aシグナル伝達におけるグリコサミノグリカンの関与2007
- Author(s)
  池上優美, 石田美穂, 灘中里美, 菅原一幸, 北川裕之
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] Glycosaminoglycan Research for 30 Years: Structure, Biosynthesis, and Functions.2007
- Author(s)
  Kazuyuki Sugahara
- Organizer
  5^<th> International Conference on Proteoglycans
- Place of Presentation
  Rio de Janeiro, Brazil
- Year and Date
  2007-09-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Glycobiology of proteoglycan signaling in brain development.2007
- Author(s)
  Kazuyuki Sugahara
- Organizer
  FEBS advanced lecture course
- Place of Presentation
  Patras, Greece
- Year and Date
  2007-05-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Two Related but Distinct Chondroitin Sulfate Mimetope Octasaccharide Sequences Recognized by Monoclonal Antibody WF6.2007
- Author(s)
  Kazuyuki Sugahara
- Organizer
  Glyco 19 (XIX International Symposium on Glycoconjugates)
- Place of Presentation
  Cairns
- Year and Date
  2007-07-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Involvement of chondroitin sulfate synthase-3(ChSy-2)in chondroitin polymerization2007
- Author(s)
  奥浦由佳, 泉川友美, 宇山徹, 菅原一幸, 北川裕之
- Organizer
  第27回日本糖質学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] コンドロイチン6-O-硫酸基転移酵素-1を過剰発現するトランスジェニックマウスの脳に発現するコンドロイチン硫酸の解析2007
- Author(s)
  迫田直樹, 三上雅久, 菅原一幸, 多屋長治, 北川裕之
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] Chondroitinase-Mediated Degradation of Rare 3-O-Sulfated Glucuronic acid in Functional Oversulfated Chondroitin Sulfate Chains.2007
- Author(s)
  D. Fongmoon, A.K. Shetty, B. Basappa, S. Yamada, M. Sugiura, P. Kongtawelert, and K. Sugahara
- Organizer
  Glycol9 (XIX International Symposium on Glycoconjugates)
- Place of Presentation
  Cairns
- Year and Date
  2007-07-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Functions of chondroitin sulfate/dermatan sulfate in the brain development: Critical roles of"E"and/or"iE"disaccharide units recognized by a single chain antibody GD3G7.2007
- Author(s)
  菅原一幸
- Organizer
  Glycobiology and Sphingobiology 2007 (GS2007)-Hakomori Commemorative Forum-.
- Place of Presentation
  徳島
- Year and Date
  2007-02-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Neuritogenic Activity And Mechanism of BRAIN Chondroitin/Dermatan Sulfate Hybrid Chains.2007
- Author(s)
  Kazuyuki Sugahara
- Organizer
  Benzon Symposium No. 54, "Glycosylation: Opportunities in Drug Development"
- Place of Presentation
  Copenhagen
- Year and Date
  2007-06-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Proteoglycan Signaling in Brain Development.2007
- Author(s)
  Kazuyuki Sugahara
- Organizer
  BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会)
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Involvement of chondroitin sulfate glucuronyltransferase(Chondroitin synthase-3) in chondroitin polymerization2007
- Author(s)
  泉川友美, 塩澤章子, 田村純一, 菅原一幸, 北川裕之
- Organizer
  第27回日本糖質学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] Novel Sulfated Octa- and Decasaccharides from Squid Cartilage Chondroitin Sulfate E: Sequencing and Application for Determination of the Epitope Structure of the Monoclonal Antibody MO-2252007
- Author(s)
  Sarama Sathyaseelan Deepa, Kittiwan Kalayanamitra, Yumi Ito, Prachya Kongtawelert, Shigeyuki Fukui, Shuhei Yamada, Tadahisa Mikami, Kazuyuki Sugahara
- Organizer
  The 27^<th> Japanease Carbohydrate Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2007-08-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Glycobiology of Proteoglycan Signaling in Brain Development.2007
- Author(s)
  Kazuyuki Sugahara
- Organizer
  Pierre Fabre Meeting "Proteoglycans and Glycosaminoglycans as Therapeutic Targets and Tools"
- Place of Presentation
  Soreze, France
- Year and Date
  2007-10-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Neuritogenic Activity And Mechanism of BRAIN Chondroitin/Dermatan Sulfate Hybrid Chains2007
- Author(s)
  Sugahara K, Li F, & Shetty AK
- Organizer
  Benzon Symposium No.54, "Glycosylation: Opportunities in Drug Development"
- Place of Presentation
  Copenhagen
- Year and Date
  2007-06-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Occurrence of a non-sulfated chondroitin proteoglycan in the dried saliva of collocalia swiftlets (edible bird's nest)2007
- Author(s)
  Hiroki Nakagawa, Yoichiro Hama, Toshihisa Sumi, Su-Chen Li, Karol Maskos, Kittiwan Kalayanamitra, Shuji Mizumoto, Kazuyuki Sugahara, Yu-The Li
- Organizer
  The 127th Japanease Pharmaceutical Symposium
- Place of Presentation
  Toyama
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Fate and Detection of Rare 3-O-Sulfated Glucuronic Acid-containing Disaccharides in Various Chondroitin Sulfate Preparations2007
- Author(s)
  Ajaya Kumar Shetty, Duriya Fongmoon, Basappa, Shuhei Yamada, Kazuyuki Sugahara
- Organizer
  The 127th Japanease Pharmaceutical Symposium
- Place of Presentation
  Toyama
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] 「研究成果報告書概要(欧文)」より2007
- Author(s)
  Kazuyuki Sugahara, Fuchuan Li, Ajaya Shetty, Shuji Mizumoto, Anurag Purushothaman, Junko Fukuda, Chie Mitsunaga, Tadahisa Mikami, Hiroshi Kitagawa, Gerdy B. ten Dam, and Toin H. van Kuppevelt
- Organizer
  BMB2007
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Occurrence of a non-sulfated chondroitin proteoglycan in the dried saliva of collocalia swiftlets (edible bird's nest)2007
- Author(s)
  Hiroki Nakagawa, Yoichiro Hama, Toshihisa Sumi, Su-Chen Li, Karol Maskos, Kittiwan Kalayanamitra, Shuji Mizumoto, Kazuyuki Sugahara, Yu-The Li
- Organizer
  The 27^<th> Japanease Carbohydrate Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2007-08-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] EXTL2を過剰発現するトランスジェニックマウスの解析2007
- Author(s)
  庄司奈緒子, 周少波, 谷口史恭, 江草徳幸, 灘中里美, 多屋長治, 菅原一幸, 北川裕之
- Organizer
  第27回日本糖質学会年会v
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] The tumor suppressor EXT-like gene EXTL2 regulates glycosaminoglycan amounts2007
- Author(s)
  鍵山正二, 周少波, 庄司奈緒子, 谷口史恭, 江草徳幸, 灘中里美, 多屋長治, 菅原一幸, 北川裕之
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390025
[Presentation] Two Related but Distinct Chondroitin Sulfate Mimetope Octasaccharide Sequences Recognized by Monoclonal Antibody WF6.2007
- Author(s)
  K. Sugahara
- Organizer
  Glyco19(XIX International Symposium on Glycoconjugates)
- Place of Presentation
  Cairns
- Year and Date
  2007-07-19
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Chondroitinase-Mediated Degradation of Rare 3-O-Sulfated Glucuronic Acid in Functional Oversulfated Chondroitin Sulfate Chains2007
- Author(s)
  Ajaya K Shetty, Duriya Fongmoon, Basappa, Shuhei Yamada, Makiko Sugiura, Prachya Kongtawelert and Kazuyuki Sugahara
- Organizer
  BMB2007
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Chondroitin Sulfate E Directly Interacts with Herpes Simplex Virus Attachment Glycoprotein C and Exhibits Potent Antiviral Activity2006
- Author(s)
  Satomi Naito, Shuhei Yamada, Kicki Bergefall, Edward Trybala, Maria Johansson, Torn Uyama, Hiroshi Kitagawa, Kazuyuki Sugahara, Tomas Bergstrom
- Organizer
  20^<th> IUBMB International Congress of Biochemistry and Molecular Biology and 11<th> FAOBMB Congress
- Place of Presentation
  Kyoto
- Year and Date
  2006-06-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Glycosaminoglycans in Hydra magnipapillata2006
- Author(s)
  Shuhei Yamada, Hideto Morimoto, Toshitaka Fujisawa, Kazuyuki Sugahara
- Organizer
  Extracellular Glycomatrix in Health and Disease
- Place of Presentation
  Awaji
- Year and Date
  2006-06-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] 脳の発達におけるコンドロイチン/デルマタン硫酸ハイブリッド鎖の機能2006
- Author(s)
  菅原一幸
- Organizer
  第26回日本糖質学会年会
- Place of Presentation
  仙台
- Year and Date
  2006-08-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Structural determination of a sulfated octasaccharide isolated from shark cartilage chondroitin sulfate2006
- Author(s)
  Peraphan Pothacharoen, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Timothy Hardingham, Kazuyuki Sugahara, P rachya Kongtawelert
- Organizer
  Extracellular Glycomatrix in Health and Disease
- Place of Presentation
  Awaji
- Year and Date
  2006-06-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Chondroitin/dermatan sulfate hybrid chain involved in cerebellar development2006
- Author(s)
  Shuji Mizumoto, Chie Mitsunaga, Junko Fukuda, Tadahisa Mikami, Kazuyuki Sugahara
- Organizer
  The 127<th> Japanease Pharmaceutical Symposium (Hokkaido branch)
- Place of Presentation
  Sapporo
- Year and Date
  2006-12-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Novel Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains from Shark Liver, Which Exhibit Potent Neuritogenic Activities Mediated by HGF and Pleiotrophin2006
- Author(s)
  Fuchuan Li, Ajaya Kumar Shetty, Kazuyuki Sugahara
- Organizer
  The 127<th> Japanease Pharmaceutical Symposium (Hokkaido branch)
- Place of Presentation
  Sapporo
- Year and Date
  2006-12-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Functions and structural motifs of chondroitin sulfate/dermatan sulfate2006
- Author(s)
  Kazuyuki Sugahara
- Organizer
  The 12<th> Gordon Research Conference on Proteoglycans
- Place of Presentation
  Andover, USA
- Year and Date
  2006-07-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Novel Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains from Shark Liver, Which Exhibit Specific Growth Factor-binding and Potent Neuritogenic Activities2006
- Author(s)
  Fuchuan Li, Ajaya Kumar Shetty, Kazuyuki Sugahara
- Organizer
  XXVIth Japanease Carbohydrate Symposium
- Place of Presentation
  Sendai
- Year and Date
  2006-08-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Functions of chondroitin sulfate/dermatan sulfate in the brain development: Critical roles of E and/or iE disaccharide units recognized by a specific antibody2006
- Author(s)
  Kazuyuki Sugahara
- Organizer
  Extracellular Glycomatrix in Health and Disease
- Place of Presentation
  Awaji
- Year and Date
  2006-06-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Chondroitin sulfate/dermatan sulfate hybrid chains in the development of cerebellum: spatiotemporal regulation of the expression of critical disulfated disaccharide by specific sulfotransferases.2006
- Author(s)
  菅原一幸
- Organizer
  5th International Symposium on Glycosyltransferases.(GlycoT 2006)
- Place of Presentation
  つくば
- Year and Date
  2006-06-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Development of Analytical Method to Detect Rare 3-O-Sulfated Glucuronic Acid-containing Disaccharides in Various Chondroitin Sulfate Preparations2006
- Author(s)
  Duriya Fongmoon, Ajaya Kumar Shetty, Basappa, Shuhei Yamada, Kazuyuki Sugahara
- Organizer
  XXVIth Japanease Carbohydrate Symposium.
- Place of Presentation
  Sendai
- Year and Date
  2006-08-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Chondroitinase ACI-resistant hexasaccharides isolated from shark cartilage chondroitin sulfate: Structures and binding activities toward signaling molecules and antibody2006
- Author(s)
  Kittiwan Kalayanamitra, Shuji Mizumoto, Sarama Sathyaseelan Deepa, Prachya Kongtawelert, Shigeyuki Fukui, Kazuyuki Sugahara
- Organizer
  Extracellular Glycomatrix in Health and Disease
- Place of Presentation
  Awaji
- Year and Date
  2006-06-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] A Novel Pleotrophin-Binding Hexasaccharide Sequence Isolated from Shark Skin Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains2006
- Author(s)
  Fuchuan Li, Chilkunda D. Nandini, Xingfeng Bao, Takashi Muramatsu, Kazuyuki Sugahara
- Organizer
  XXVIth Japanease Carbohydrate Symposium.
- Place of Presentation
  Sendai
- Year and Date
  2006-08-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Chondroitin sulfate/dermatan sulfate hybrid chains in the development of cerebellum: spatiotemporal regulation of the expression of critical disulfated disaccharide by specific sulfotransferases2006
- Author(s)
  Kazuyuki Sugahara
- Organizer
  5<th> International Symposium on Glycosyltransferases (GlycoT 2006)
- Place of Presentation
  Tsukuba
- Year and Date
  2006-06-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Functions and structural motifs of chondroitin sulfate/dermatan sulfate.2006
- Author(s)
  菅原一幸
- Organizer
  The 12th Gordon Research Conference on Proteoglycans.
- Place of Presentation
  Andover, USA
- Year and Date
  2006-07-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Functions of chondroitin sulfate/dermatan sulfate in the brain development:Critical roles of E and/or iE disaccharide units recognized by a specific antibody.2006
- Author(s)
  菅原一幸
- Organizer
  Extracellular Glycomatrix in Health and Disease.
- Place of Presentation
  淡路島
- Year and Date
  2006-06-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Development of Analytical Method to Detect Rare 3-O-Sulfated Glucuronic Acid-containing Disaccharides in Various Chondroitin Sulfate Preparations2006
- Author(s)
  Duriya Fongmoon, Ajaya Kumar Shetty, Basappa, Shuhei Yamada, Kazuyuki Sugahara
- Organizer
  The 43th Japanease Biochemistry Symposium (Hokkaido Branch)
- Place of Presentation
  Sapporo
- Year and Date
  2006-11-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences involved in brain development
- Author(s)
  ○Shuji Mizumoto, Saori Murakoshi, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fuku5, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
- Organizer
  2012年度　包括型脳科学研究推進支援ネットワーク・夏のワークショップ
- Place of Presentation
  仙台国際センター(仙台)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Wobble chondroitin sulfate oligosaccharide motifs and mass production of oligosaccharides
- Author(s)
  Kazuyuki Sugahara
- Organizer
  The 21st Symposium on Glycosaminoglycans
- Place of Presentation
  Loveno, Lake Como(イタリア)
- Invited
- Data Source
  KAKENHI-PUBLICLY-24110501
[Presentation] Integrated neuroglycobiology for proteoglycans and chondroitin sulfate-binding proteins
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, Kosei Takeuchi, Yoshiaki Nakayama, Akira Kurosaka, Keiichiro Matsushima, Nobuyuki Miyamoto, Wataru Takada, Hirofumi Kodera, Naomichi Matsumoto, Hirotomo Saitsu, Gunnar Dick, James W. Fawcett, and Jessica C. F. Kwok
- Organizer
  nternational Symposium on Glyco-Neuroscience
- Place of Presentation
  Awaji Yumebutai International Conference Center(淡路)
- Data Source
  KAKENHI-PUBLICLY-24110501
[Presentation] Wobble chondroitin sulfate oligosaccharide motifs and mass production of oligosaccharides
- Author(s)
  Kazuyuki Sugahara
- Organizer
  The 21st Symposium on Glycosaminoglycans
- Place of Presentation
  Loveno, Lake Como(イタリア)
- Invited
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] グリコサミノグリカンの生合成に関わる酵素の新規変異による脊椎骨端骨幹端異形成症とエーラス・ダンロス症候群の糖鎖生物学的研究
- Author(s)
  ○水本秀二, 中島正宏, Thomas Muller, 三宅紀子, Indrajit Suresh, 古川諒, 小松由枝, 松本直通, Andreas R Janecke, 池川志郎, 菅原一幸
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪国際交流センター（大阪）
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] RAGEは癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する
- Author(s)
  ○水本秀二, 高橋潤, 菅原一幸
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島市民文化ホール(鹿児島)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Mass preparation of oligosaccharides with intestinal absorption capacity by hydrolysis of chondroitin sulfate polysaccharides with subcritical water microreaction system
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, and Nobuyuki Miyamoto
- Organizer
  The 13th International Conference on Functional and Medical Foods with Bioactive Compounds: Science and Practical Applications”
- Place of Presentation
  The Kyoto Prefectural University of Medicine (Kyoto)
- Data Source
  KAKENHI-PUBLICLY-24110501
[Presentation] Characterization of a receptor for glycosaminoglycans that mediate experimental lung metastasis
- Author(s)
  Kazuyuki Sugahara
- Organizer
  The 15th Gordon Research Conference on Proteoglycans
- Place of Presentation
  Proctor Academy(米国)
- Invited
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] コンドロイチン硫酸/デルマタン硫酸の生合成に関わる酵素の変異による骨・皮膚疾患の糖鎖生物学的研究
- Author(s)
  ○水本秀二, 中島正宏, Thomas Muller, 三宅紀子, Indrajit Suresh, 古川諒, 小松由枝, 松本直通, Andreas R Janecke, 池川志郎, 菅原一幸
- Organizer
  日本生化学会北海道支部支部例会第50回記念大会
- Place of Presentation
  北海道大学医学部(札幌)
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] PAPS合成酵素2の変異によって引き起こされる常染色体劣性型短脊柱症
- Author(s)
  ○水本秀二, 飯田有俊, Pelin Ozlem Simsek-Kiper, 星野冬馬, Nursel Elcioglu, Eva Horemuzova, Stefan Geiberger, Gozde Yesil, Hulya Kayserili, Gulen Eda Utine, Koray Boduroglu, 渡邉成彦, 大橋博文, Yasemin Alanay, 西村玄, 池川志郎, 菅原一幸
- Organizer
  日本薬学会第134回年会
- Place of Presentation
  熊本大学工学部(熊本)
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage. Insights into the sugar sequences involved in brain development
- Author(s)
  Kazuyuki Sugahara
- Organizer
  The 8th International Conference on Proteoglycans
- Place of Presentation
  Hotel Collegium Glashutten(ドイツ)
- Data Source
  KAKENHI-PUBLICLY-24110501
[Presentation] Receptor for Advanced Glycation End Products (RAGE)は癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する
- Author(s)
  ○水本秀二, 高橋潤, 菅原一幸
- Organizer
  日本薬学会北海道支部第138回例会
- Place of Presentation
  札幌コンベンションセンター(札幌)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] がんの肺転移に関わるグリコサミノグリカン受容体(RAGE)の同定
- Author(s)
  ○高橋潤、水本秀二、菅原一幸
- Organizer
  第49 回日本生化学会北海道支部例会
- Place of Presentation
  北海道大学(札幌市）
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Receptor for Advanced Glycation End-products (RAGE) functions as a receptor for glycosaminoglycans involved in pulmonary metastasis
- Author(s)
  ◯Shuji MIZUMOTO, Jun TAKAHASHI, Kazuyuki SUGAHARA
- Organizer
  The 10th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokaido Univ. (Sapporo)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Receptor for Advanced Glycation End-products (RAGE) Functions as Receptor for Sulfated Glycosaminoglycans (GAGs): Anti-RAGE Antibody or Sulfated GAGs Inhibit Lung Metastasis of Tumor Cells
- Author(s)
  Kazuyuki SUGAHARA, Jun TAKAHASHI, Shuji MIZUMOTO
- Organizer
  22nd International Symposium on Glycoconjugates
- Place of Presentation
  Dalian Institute of Chemical Phisics, Chinese Academy of Sciences(中国)
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] Receptor for Advanced Glycation End-products (RAGE) functions as a receptor for glycosaminoglycans involved in pulmonary metastasis
- Author(s)
  ◯Shuji MIZUMOTO, Jun TAKAHASHI, Kazuyuki SUGAHARA
- Organizer
  The 10th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ.(Sapporo)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] GAG signals involved in pulmonary metastasis of tumor cells
- Author(s)
  Kazuyuki Sugahara
- Organizer
  The 20th Symposium on glycosaminoglycans
- Place of Presentation
  Villa VigoniVilla(イタリア）
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] サメヒレ軟骨コンドロイチン硫酸由来の新規な六糖配列の単離
- Author(s)
  ◯水本秀二, 村越早織, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, 福井成行, Prachya Kongtawelert, 山田修平, 菅原一幸
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Receptor for Advanced Glycation End Products (RAGE)は癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する
- Author(s)
  ○水本秀二、高橋潤、菅原一幸
- Organizer
  日本薬学会北海道支部第138回例会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Mechanism of glycosaminoglycan-mediated tumor metastasis
- Author(s)
  Kazuyuki Sugahara and Shuji Mizumoto
- Organizer
  The 27th International Carbohydrate Symposium
- Place of Presentation
  Indial Institute of Science (インド)
- Invited
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Wobble chondroitin sulfate oligosaccharide motifs and mass production of oligosaccharides
- Author(s)
  Kazuyuki Sugahara
- Organizer
  The 21st Symposium on Glycosaminoglycans
- Place of Presentation
  Loveno, Lake Como(イタリア）
- Invited
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Receptor for Advanced Glycation End-products (RAGE) Functions as Receptor for Sulfated Glycosaminoglycans (GAGs): Anti-RAGE Antibody or Sulfated GAGs Inhibit Lung Metastasis of Tumor Cells
- Author(s)
  Kazuyuki SUGAHARA, Jun TAKAHASHI, Shuji MIZUMOTO
- Organizer
  22nd International Symposium on Glycoconjugates
- Place of Presentation
  Dalian Institute of Chemical Phisics, Chinese Academy of Sciences(中国)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Novel CS-E-Binding Proteins in Mouse Brain That May Be Involved in the Neurite Outgrowth Promoting Mechanism through Chondroitin Sulfate E-Type
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, and Kosei Takeuchi
- Organizer
  Gordon Research Conference on Proteoglycans 2014
- Place of Presentation
  Andover, USA
- Year and Date
  2014-07-07 – 2014-07-10
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Novel chondroitin sulfate oligosaccharide motifs as biomarkers: Insights into their involvement in the brain development
- Author(s)
  Kazuyuki Sugahara and Shuji Mizumoto
- Organizer
  The 10th International Symposium on Cell Surface Macromolecules
- Place of Presentation
  Fortune Park Panchwat(インド)
- Invited
- Data Source
  KAKENHI-PUBLICLY-24110501
[Presentation] 糖鎖生物学による癌の肺転移の分子メカニズムの解明　-抗癌剤開発に向けての洞察-
- Author(s)
  Kazuyuki Sugahara
- Organizer
  第１６回未来創薬・医療イノベーションセミナー
- Place of Presentation
  北海道大学(札幌市）
- Invited
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] 亜臨界水を利用したコンドロイチン硫酸オリゴ糖の大量調製
- Author(s)
  山田修平、松嶋景一郎、浦晴雄、宮本宣之、菅原一幸
- Organizer
  ５９回日本薬学会東海支部総会・大会
- Place of Presentation
  名城大学薬学部(名古屋)
- Data Source
  KAKENHI-PUBLICLY-24110501
[Presentation] Mass preparation of oligosaccharides with intestinal absorption capacity by hydrolysis of chondroitin sulfate polysaccharides with subcritical water microreaction system
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, Nobuyuki Miyamoto
- Organizer
  he 13th International Conference on Functional and Medical Foods with Bioactive Compounds
- Place of Presentation
  The Kyoto Prefectural University of Medicine(京都)
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] Receptor for AdvancedGlycation End-products (RAGE) Functions as a Receptor for Pulmonary Metastasis Mediated by Sulfated Glycosaminoglycans
- Author(s)
  Kazuyuki SUGAHARA
- Organizer
  2nd International Anatomical Sciences and Cell Biology Conference & 36th Annual Conference of the Anatomy Association of Thailand
- Place of Presentation
  Chiang Mai Grandview Hotel & Convention Center(タイ)
- Invited
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Mass preparation of oligosaccharides with intestinal absorption capacity by hydrolysis of chondroitin sulfate polysaccharides with subcritical water microreaction system
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, and Nobuyuki Miyamoto
- Organizer
  The 13th International Conference on Functional and Medical Foods with Bioactive Compounds: Science and Practical Applications”
- Place of Presentation
  The Kyoto Prefectural University of Medicine (京都)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Mechanism of glycosaminoglycan-mediated tumor metastasis
- Author(s)
  Kazuyuki Sugahara and Shuji Mizumoto
- Organizer
  The 27th International Carbohydrate Symposium
- Place of Presentation
  Indial Institute of Science(インド)
- Invited
- Data Source
  KAKENHI-PROJECT-25670018
[Presentation] RAGEは癌細胞の肺転移に関わるコンドロイチン硫酸の受容体として機能する
- Author(s)
  ○ 水本秀二, 高橋潤, 菅原一幸
- Organizer
  第３１回日本糖質学会年会
- Place of Presentation
  鹿児島市民ホール(鹿児島市）
- Data Source
  KAKENHI-PROJECT-23390016

1. YAMADA Shuhei (70240017)

# of Collaborated Projects: 19 results

# of Collaborated Products: 127 results
2. KITAGAWA Hiroshi (40221915)

# of Collaborated Projects: 9 results

# of Collaborated Products: 31 results
3. MIZUMOTO Shuji (40443973)

# of Collaborated Projects: 6 results

# of Collaborated Products: 141 results
4. YAMASHINA Ikuo (70025675)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
5. MIKAMI Tadahisa (20330425)

# of Collaborated Projects: 6 results

# of Collaborated Products: 16 results
6. FUNAKOSHI Ikuo (10025702)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
7. IKEGAWA Shiro (30272496)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
8. MATSUMOTO Naomichi (80325638)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
9. MIYAKE Noriko (40523494)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
10. KOSHO Tomoki (90276311)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
11. KAWASAKI Toshisuke (50025706)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. OGAWA Tomoya (30087572)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. ASANO Masahide (50251450)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 羽渕脩躬 (90024067)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. LINDAHL Ulf

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. YAMASHITA Tadashi (30220338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. YOSHIZAWA Chikako (80533653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KANDA Atsuhiro (80342707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. NOMIZU Motoyoshi (00311522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TAYA Choji (90175456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MIKAMI Tadahisa (20033425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 鈴木明身 (70134533)

# of Collaborated Projects: 1 results

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23. 伊東信 (40253512)

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24. 中田博 (90113141)

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25. 岩森正男 (90110022)

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26. 飯田静夫 (00009987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 松本勲武 (70012664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 西川義尚 (20109953)

# of Collaborated Projects: 1 results

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29. 牧田章 (60004561)

# of Collaborated Projects: 1 results

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30. 村松喬 (00030891)

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31. 木全弘治 (10022641)

# of Collaborated Projects: 1 results

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32. 柳下正樹 (70132793)

# of Collaborated Projects: 1 results

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33. 齋藤政樹 (60012762)

# of Collaborated Projects: 1 results

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34. 田井直 (70112092)

# of Collaborated Projects: 1 results

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35. 田村純一 (30221401)

# of Collaborated Projects: 1 results

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36. 木下亜希子 (30289037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. YOSHIDA Keiichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. NAKAJIMA Motowo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. STEFAN Mundlos

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
40. LIHADH Al-gazali

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
41. KATRIN Hoffmann

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. ANDREAS Janecke

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
43. ULF Lindahl

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. KHOO KayーHoo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. FAISSNER And

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. DELL Anne

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. FAESSNER And

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. HINDSGAUL Ol

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. BAO Xingfeng

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. LI Fuchuan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. 三橋進

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. MIHASHI Susumu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. Janecke Andreas

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
54. Nürnberg Peter

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. Kennerknecht Ingo

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
56. TANI Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
57. NAKAMURA Kazuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. OKAMOTO Nobuhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
59. 鬼頭浩史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. 鶴崎美徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
61. 和田芳直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
62. 湯浅勲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
63. 前垣義弘

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# of Collaborated Products: 1 results
64. 加藤光広

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# of Collaborated Products: 1 results
65. 才津浩智

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# of Collaborated Products: 1 results
66. 小寺啓文

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# of Collaborated Products: 1 results
67. 藤倉大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SUGAHARA Kazuyuki 菅原 一幸

Research Projects

Research Products

Co-Researchers

Involvement of Sulfated Gycosaminoglycan in the Pathogenesis of Diabetic Retinopathy

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Drug discovery of innovative small molecules with inhibition of RAGE-GAG interactionPrincipal Investigator

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Roles of chondroitin sulfate interacting with RAGE involved in tumor and Alzheimer's disease

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プロテオグリカンとコンドロイチン硫酸結合性タンパク質に関する統合的神経糖鎖生物学Principal Investigator

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Review Section

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Structural and functional studies on the novel hyaluronidase trying for its clinical application

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Molecular mechanism for roles of chondroitin sulfate in tumor metastasisPrincipal Investigator

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Pathogenic mechanisms of the bone diseases caused by defect in chondroitin sulfate biosynthesis

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Identification of endo-type chondroitin sulfate hydrolases applicable to neuronal regenerative therapy

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Molecular mechanism of proteoglycan signalingsPrincipal Investigator

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Biosynthetic mechanism and functional analysis of sulfated glycosaminoglycans aimed at elucidating the pathology and therapy

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Functional analysis of glycosaminoglycans as a potential drug target and the decoding of carbohydrate signaling of the functional domainsPrincipal Investigator

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胎児脳のグリコサミノグリカンによる神経幹細胞の分化と神経突起伸長の分子メカニズムPrincipal Investigator

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Development of a fundamental technology, which is applicable to drug development and therapeutic applications through analysis of sulfated glycosaminoglycan chainsPrincipal Investigator

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SUGAHARA Kazuyuki 菅原一幸