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Yamada Shuhei  山田 修平

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YAMADA Shuhei  山田 修平

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Researcher Number 70240017
Other IDs
External Links
Affiliation (Current) 2025: 名城大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2012 – 2024: 名城大学, 薬学部, 教授
2013: 北海道大学, 大学院・先端生命科学研究院, 准教授
2007 – 2011: Hokkaido University, Faculty of Advanced Life Science, Associate Professor
2006: Hokkaido Univ., Faculty of Advanced Life Science, Associate Professor., 大学院先端生命科学研究院, 助教授
2000 – 2005: Dept.of Biochemistry, KOBE PHARMACEUTICAL UNIVERSITY Lecturer, 薬学部, 講師 … More
2002: 神戸薬大, 薬学部, 講師
1995 – 1999: 神戸薬科大学, 薬学部, 助手
1995: Kobe Pharmaceutical Univ.Instructor Dept.of Biochemistry, 薬学部・生化学, 助手
1994 – 1995: 神戸薬科大学, 薬学部・生化学教室, 助手
1994: 神戸薬科大学, 生化部, 助手
1992 – 1993: 神戸女子薬科大学, 薬学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / 医薬分子機能学 / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological pharmacy / Biological Sciences
Except Principal Investigator
Biological pharmacy / Biological pharmacy / Structural biochemistry / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 48040:Medical biochemistry-related / 医薬分子機能学
Keywords
Principal Investigator
ヘパラン硫酸 / グリコサミノグリカン / コンドロイチン硫酸 / 硫酸化オリゴ糖 / 硫酸化グリコサミノグリカン / ヘパリン / ヒアルロニダーゼ / ヒアルロン酸 / ノックアウトマウス / ^1H NMR … More / 生合成 / 糖転移酵素 / へパラン硫酸 / EXTL3 / 脳 / 細胞増殖因子 / アフリカツメガエル / アンジオモジュリン / 血管新生 / プロテオグリカン / マルチオミクス / 遺伝性疾患 / キシロース転移酵素 / 遺伝病 / T細胞 / 癌 / BlAcore / Hydra / Xenopus / model organism / growth factor / chondroitin sulfate / heparan sulfate / glycosaminoglycan / BIAcore / ヒドラ / モデル生物 / 糖鎖 / 神経 / 基質特異性 / 加水分解酵素 / ヒアル / 神経再生 / C型肝炎ウィルス / サイトカイン / C型肝炎ウイルス / 肝再生 / 癌抑制遺伝子 / EXT1 / 遺伝性多発性外骨腫 / ヘパラナーゼ / 癌転移 / シンデカン / 表面プラズモン共鳴 / ガン / 発生 / TAF / アンジオモデュリン / フォリスタチン / 塩基性繊維芽細胞増殖因子 / PGP架橋 / ウリナリートリブシンインヒビター / インター-α-トリプシンインヒビター / グルクロン酸2-硫酸 / ヘパリチナーゼ / ヘパリナーゼ … More
Except Principal Investigator
コンドロイチン硫酸 / デルマタン硫酸 / プロテオグリカン / ヘパラン硫酸 / グリコサミノグリカン / ヘパリン / chondroitin sulfate / 硫酸化 / 硫酸化オリゴ糖 / プレイオトロフィン / 硫酸基転移酵素 / 増殖因子 / 神経突起伸長 / 神経突起 / 糖転移酵素 / dermatan sulfate / neurite outgrowth / heparan sulfate / glycosaminoglycan / EXT / シンデカン / 肝細胞増殖因子 / イズロン酸 / 脳 / 糖尿病 / chondroitin polymerizing factor / sulfotransferase / RNAi / ガン抑制遺伝子 / 線虫 / glycosyltransferase / グルクロン酸転移酵素 / 癌抑制遺伝子 / NMR / Sulfation / 硫酸化グリコサミノグリカン / RAGE / 癌 / 遺伝病 / アピカン / MS / 2-アミノベンズアミド / ミッドカイン / フォリスタチン / 細胞増殖因子 / コンドロイチナーゼ / ヘパリナーゼ / 包括的病態解析 / iPS細胞 / マウスモデル / 筋拘縮型エーラス・ダンロス症候群 / 遺伝性骨・皮膚疾患 / ゴルジ体 / ゴルジン / 皮膚弛緩症 / 骨系統疾患 / 脊椎肋骨異骨症 / 結合組織疾患 / LFNG / 免疫不全症 / 骨異形成性老人性皮膚症 / 脊椎骨端骨幹端異形成症 / エーラス・ダンロス症候群 / GORAB / Golgin / シンデカン4 / コアタンパク質シンデカン4 / 膵β細胞 / インスリン分泌 / コアタンパク質Syndecan-4 / ヘパラン硫酸プロテオグリカン / てんかん / 老化 / 骨・皮膚疾患 / アルツハイマー病 / pleiotrophin / hepatocyte growth factor / carbohydrate chain / hydra / iduronic acid / herpes simplex virus / 神経細胞 / 小脳 / 糖鎖 / ヒドラ / pleiotrpohin / RNA intereference / spondyloepiphysial dysplasia / プライオトロフィン / RANi / 先天性脊椎・骨端異形成症 / RNA / RNA Interference / コンドロイチン重合化因子 / 先天性脊髄・骨端異形成症 / 硫酸基転位酵素 / chondroitin synthase / N-アセチルガラクトサミン転移酵素 / ショウジョウバエ / グルクロン酸転位酵素 / 糖転位酵素 / コンドロイチン重合因子 / コンドロイチン合成酵素 / amyloid precursor protein / glycosyltransferases / EXT tumor suppressor genes / tumor metastasis / heparanase / heparin-binding growth factors / 遺伝子構造 / グルコサミン-3硫酸 / ラミニン / エンド-beta-グルクロニダーゼ / X線結晶構造解析 / アミロイド前駆体タンパク質 / EXT癌抑制遺伝子 / 癌転移 / ヘパラナーゼ / ヘパリン結合性増殖因子 / chondroitinase / heparinase / sulfated oligosaccharides / heparin sulfate / heparin / 螢光標識 / デルマタン流酸 / C2-エピメリゼーション / マンノサミン / コンドロイチナーゼC / angiogenesis / EXT gene family / tumor suppressor / ヘバラン硫酸 / コンドロイチン / N-アセチルグルコサミン / アンジオモジュリン / コンドロイチン硫酸E / 血管新生 / EXT遺伝子ファミリー / Sulfated Oligosaccharides / Chondroitin Sulfate / Dermatan Sulfate / Glycosaminoglycan / ESI / ウリマリ-トリプシンインヒビター / インターα-トリプシンインヒビター / GalNAc転移酵素 / ウリナリートリプシンインヒビタ / インター-α-トリプシンインヒビター / Galactose / Glycosaminoglycans / Chondroitin sulfate / Heparin / ガラクトース硫酸 / ニュージーランド / ドイツ / 変形性関節症 / 骨形成 / ダンロス症候群/糖転移酵素/硫酸基転移酵素 / 皮膚/遺伝病/脊椎骨端異形成症/ エーラス / コンドロイチン硫酸/デルマタン硫酸/骨 / オリゴ糖 / プロテオミクス / ルイス肺癌細胞 / 転移 / 計科学 / 肝再生 / basic FGF / 加水分解酵素 / 単クローン抗体 / デルマタン硫酸エピメラーゼ / 計算科学 / cMet / perineuronal net / リン酸化 / プロトンNMR / NALDI-TOF / 蛍光標識 / 神系突起 / コンドロチチナーゼ / フオリスタチン / スルファターゼ / ヘパリチナーゼ Less
  • Research Projects

    (36 results)
  • Research Products

    (394 results)
  • Co-Researchers

    (48 People)
  •  Biochemical and multi-omics analysis of hereditary disorders caused by deficiency of glycosaminoglycan biosynthesisPrincipal Investigator

    • Principal Investigator
      山田 修平
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Meijo University
  •  Elucidation of the pathogenetic mechanisms of congenital diseases caused by the mutations in biosynthetic enzymes of heparan sulfatePrincipal Investigator

    • Principal Investigator
      Yamada Shuhei
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Meijo University
  •  Integrated understanding of dermatan sulfate through uncovering pathophysiology of musculocontractural Ehlers-Danlos syndrome

    • Principal Investigator
      Kosho Tomoki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Shinshu University
  •  Elucidation of the novel functions of EXTL3 involved in the biosynthesis of heparan sulfate in brains and T cellsPrincipal Investigator

    • Principal Investigator
      Yamada Shuhei
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Meijo University
  •  Analysis of insulin secretory function in syndecan-4 knockout mice

    • Principal Investigator
      Takahashi Iwao
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Iwate Medical University
  •  Mechanism of biosynthesis of glycosaminoglycan by Golgin, and its hereditary bone and skin disorders

    • Principal Investigator
      Mizumoto Shuji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Meijo University
  •  Function as well as regulation on expression of a novel hyaluronidase in cancer and inflammationPrincipal Investigator

    • Principal Investigator
      Yamada Shuhei
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Meijo University
  •  脳におけるコンドロイチン硫酸およびヒアルロン酸の代謝分解機構の解明Principal Investigator

    • Principal Investigator
      山田 修平
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Meijo University
  •  Roles of chondroitin sulfate interacting with RAGE involved in tumor and Alzheimer's disease

    • Principal Investigator
      Shiji Mizumoto
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Meijo University
  •  Structural and functional studies on the novel hyaluronidase trying for its clinical applicationPrincipal Investigator

    • Principal Investigator
      YAMADA Shuhei
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Meijo University
  •  Molecular mechanism for roles of chondroitin sulfate in tumor metastasis

    • Principal Investigator
      SUGAHARA Kazuyuki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  Pathogenic mechanisms of the bone diseases caused by defect in chondroitin sulfate biosynthesis

    • Principal Investigator
      MIZUMOTO Shuji
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  Identification of endo-type chondroitin sulfate hydrolases applicable to neuronal regenerative therapyPrincipal Investigator

    • Principal Investigator
      YAMADA Shuhei
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  Molecular mechanism of proteoglycan signalings

    • Principal Investigator
      SUGAHARA Kazuyuki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  Study on the structure and functions of sulfated glycosaminoglycans involved in the development or treatment of liver diseases.Principal Investigator

    • Principal Investigator
      YAMADA Shuhei
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  Functional analysis of glycosaminoglycans as a potential drug target and the decoding of carbohydrate signaling of the functional domains

    • Principal Investigator
      SUGAHARA Kazuyuki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  胎児脳のグリコサミノグリカンによる神経幹細胞の分化と神経突起伸長の分子メカニズム

    • Principal Investigator
      菅原 一幸
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
      Kobe Pharmaceutical University
  •  Changes in the specificity of the interaction between cell growth/differentiation factors and glycosaminoglycans during development and differentiation.Principal Investigator

    • Principal Investigator
      YAMADA Shuhei
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      HOKKAIDO UNIVERSITY
      Kobe Pharmaceutical University
  •  Development of a fundamental technology, which is applicable to drug development and therapeutic applications through analysis of sulfated glycosaminoglycan chains

    • Principal Investigator
      SUGAHARA Kazuyuki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      KOBE PHARMACEUTICAL UNIVERSITY
  •  コンドロイチン/デルマタン硫酸の神経突起伸長促進機能とその分子メカニズム

    • Principal Investigator
      菅原 一幸
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Kobe Pharmaceutical University
  •  ヘパラン硫酸(HS)生合成酵素である癌抑制遺伝子EXT1欠損マウスのHSの解析Principal Investigator

    • Principal Investigator
      山田 修平
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kobe Pharmaceutical University
  •  癌の浸潤・転移に関与するヘパラナーゼ及び血管新生調節因子アンジオモジュリンの研究Principal Investigator

    • Principal Investigator
      山田 修平
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Kobe Pharmaceutical University
  •  Analysis of the biosynthetic mechanism and functions of glycosaminogycans by manipulating the genes encoding biosynthetic enzymes.

    • Principal Investigator
      SUGAHARA Kazuyuki
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kobe Pharmaceutical University
  •  Development of the haparan sulfate-based anti-cancer drugs

    • Principal Investigator
      SUGAHARA Kazuyuki
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      KOBE PHARMACEUTICAL UNIVERSITY
  •  発生や分化に伴うヘパラン硫酸の微細構造と増殖・分化因子との結合能の変動と相関Principal Investigator

    • Principal Investigator
      山田 修平
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      医薬分子機能学
    • Research Institution
      Kobe Pharmaceutical University
  •  パートタイムプロテオグリカンへの糖鎖付加の分子スイッチの同定とその機能調節の解明

    • Principal Investigator
      菅原 一幸
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Kobe Pharmaceutical University
  •  癌性細胞接着因子の活性発現調節因子であるヘパリン、ヘパラン硫酸の構造と機能の解析Principal Investigator

    • Principal Investigator
      山田 修平
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      医薬分子機能学
    • Research Institution
      Kobe Pharmaceutical University
  •  神経突起伸長と血管新生におけるグリコサミノグリカン糖鎖の分子認識

    • Principal Investigator
      SUGAHARA Kazuyuki
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Biological pharmacy
    • Research Institution
      KOBE PHARMACEUTICAL UNIVERSITY
  •  Development of a universal sequencing method for sulfated glycosaminoglycans

    • Principal Investigator
      SUGAHARA Kazuyuki
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kobe Pharmaceutical University
  •  ヘパリン/ヘパラン硫酸の微細硫酸化構造と細胞増殖・分化因子の調節活性との相関Principal Investigator

    • Principal Investigator
      山田 修平
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      医薬分子機能学
    • Research Institution
      Kobe Pharmaceutical University
  •  細胞の増殖・分化促進活性を有する硫酸化グリコサミノグリカン糖鎖の分子認識

    • Principal Investigator
      菅原 一幸
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      医薬分子機能学
    • Research Institution
      Kobe Pharmaceutical University
  •  血中及び尿中のトリプシンインヒビターに結合した新奇コンドロイチン硫酸の構造解析Principal Investigator

    • Principal Investigator
      山田 修平
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kobe Pharmaceutical University
  •  ヘパリナーゼ、ヘパリチナーゼの基質特異性の研究Principal Investigator

    • Principal Investigator
      山田 修平
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kobe Pharmaceutical University
  •  Structure and Biosynthesis of Carbohydrate-Protein Linkage Region of Dermatan Sulfate and Chondroitin Sulfate

    • Principal Investigator
      SUGAHARA Kazuyuki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kobe Pharmaceutical University
  •  グリコサミノグリカン多糖鎖のリン酸化と硫酸化による精密硫酸化構造の意義に関する研究

    • Principal Investigator
      SUGAHARA Kazuyuki
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe Pharmaceutical University
  •  Structural Study on th Carbohydrate-Protein Linkage Region of Proteglycans

    • Principal Investigator
      SUGAHARA Kazuyuki
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kobe Women's College of Pharmacy

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All Journal Article Presentation Book Patent

  • [Book] 糖鎖生物学 (生命現象と糖鎖情報)2020

    • Author(s)
      水本秀二、山田修平
    • Total Pages
      306
    • Publisher
      名古屋大学出版会
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Book] Encyclopedia of Polymeric Nanomaterials2015

    • Author(s)
      Kazuyuki Sugahara, Shuji Mizumoto, Shuhei Yamada
    • Total Pages
      2500
    • Publisher
      Springer-Verlag
    • Data Source
      KAKENHI-PROJECT-25860037
  • [Book] Biochemical Roles of Eukaryotic Cell Surface Macromolecules2015

    • Author(s)
      Shuhei Yamada
    • Total Pages
      411
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Book] Encyclopedia of Polymeric Nanomaterials2015

    • Author(s)
      Kazuyuki Sugahara, Shuji Mizumoto, and Shuhei Yamada
    • Total Pages
      2672
    • Publisher
      Springer
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Book] 糖鎖の新機能開発 応用ハンドブック - 創薬 医療から食品開発まで2015

    • Author(s)
      山田 修平、水本秀二、菅原一幸
    • Total Pages
      628
    • Publisher
      エヌ ティー エス
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Book] Encyclopedia of Polymeric Nanomaterials2015

    • Author(s)
      Kazuyuki Sugahara, Shuji Mizumoto, and Shuhei Yamada
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Book] Biochemical Roles of Eukaryotic Cell Surface Macromolecules2015

    • Author(s)
      Shuhei Yamada
    • Total Pages
      411
    • Publisher
      Springer
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Book] Encyclopedia of Polymeric Nanomaterials2015

    • Author(s)
      Kazuyuki Sugahara, Shuji Mizumoto, and Shuhei Yamada
    • Total Pages
      2672
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Book] Chondroitin Sulfate In Encyclopedia of Polymeric Nanomaterials2015

    • Author(s)
      Kazuyuki Sugahara, Shuji Mizumoto, Shuhei Yamada
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-25860037
  • [Book] グリコサミノグリカン・プロテオグリカンの分解 In 糖鎖の新機能開発・応用ハンドブック~創薬・医療からヘルスケアまで~2015

    • Author(s)
      山田修平、水本秀二、菅原一幸
    • Publisher
      エヌ・ティー・エス
    • Data Source
      KAKENHI-PROJECT-25860037
  • [Book] Adv. Exp. Med. Biol. Vol 749, “Biochemical Roles of Eukaryotic Cell Surface Macromolecules” (Sudhakaran, P. and Surolia, A., eds.)2012

    • Author(s)
      Shuhei Yamada
    • Total Pages
      340
    • Publisher
      Springer, Heidelberg
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Book] 遺伝子医学MOOK別冊ますます重要になる細胞周辺環境(細胞ニッチ)の最新科学技術 .細胞の生存、増殖、機能のコントロールから創薬研究、再生医療まで.2009

    • Author(s)
      水本秀二,山田修平,菅原一幸
    • Total Pages
      230
    • Publisher
      メディカルドゥ
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Book] Experimental Glycoscience "Glycochemistry"(Taniguchi N., Suzuki A., Ito Y., Narimatsu H., Kawasaki T., Hase S., eds) (Microsequencing of functional chondroitin sulfate oligosaccharides)2008

    • Author(s)
      Sugahara K., Yamada S.
    • Publisher
      Springer, Tokyo
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Book] Springer, Tokyo2008

    • Author(s)
      Kazuyuki Sugahara and Shuhei Yamada
    • Publisher
      Experimental Glycoscience Glycochemistry,
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Book] タンパク質の翻訳後修飾解析プロトコール2006

    • Author(s)
      山田修平
    • Total Pages
      287
    • Publisher
      羊土社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590078
  • [Book] グリコサミノグリカン糖鎖の構造解析法2006

    • Author(s)
      山田 修平
    • Publisher
      羊土社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Book] タンパク質の翻訳後修飾解析プロトコール2005

    • Author(s)
      山田 修平
    • Total Pages
      286
    • Publisher
      羊土社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390026
  • [Book] タンパク質の翻訳後修飾解析プロトコール2005

    • Author(s)
      山田修平
    • Total Pages
      9
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-17590078
  • [Journal Article] Mice lacking nucleotide sugar transporter SLC35A3 exhibit lethal chondrodysplasia with vertebral anomalies and impaired glycosaminoglycan biosynthesis2023

    • Author(s)
      Saito S, Mizumoto S, Yonekura T, Yamashita R, Nakano K, Okubo T, Yamada S, Okamura T, Furuichi T.
    • Journal Title

      PLoS One

      Volume: 18 Issue: 4 Pages: e0284292-e0284292

    • DOI

      10.1371/journal.pone.0284292

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K05932, KAKENHI-PROJECT-23K06142, KAKENHI-PROJECT-21K06552
  • [Journal Article] Myopathy associated with dermatan sulfate-deficient decorin and myostatin in musculocontractural Ehlers-Danlos syndrome: a mouse model investigation2021

    • Author(s)
      Yuko Nitahara-Kasahara, Guillermo Posadas-Herrera, Shuji Mizumoto, Aki Nakamura-Takahashi, Yukiko U. Inoue, Takayoshi Inoue, Yoshihiro Nomura, Shin’ichi Takeda, Shuhei Yamada, Tomoki Kosho, Takashi Okada
    • Journal Title

      Frontiers in Cell and Developmental Biology

      Volume: 9 Pages: 695021-695021

    • DOI

      10.3389/fcell.2021.695021

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07054, KAKENHI-PUBLICLY-19H04922, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-20K06467
  • [Journal Article] A new mouse model of Ehlers-Danlos syndrome generated using CRISPR/Cas9-mediated genomic editing.2021

    • Author(s)
      Yuko Nitahara-Kasahara, Shuji Mizumoto, et al.
    • Journal Title

      Disease Models & Mechanisms

      Volume: 14 Issue: 12

    • DOI

      10.1242/dmm.048963

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07054, KAKENHI-PUBLICLY-19H04922, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-19K08745, KAKENHI-PROJECT-20K06467
  • [Journal Article] Systematic investigation of the skin in Chst14-/- mice: a model for skin fragility in musculocontractural Ehlers-Danlos syndrome caused by CHST14 variants (mcEDS-CHST14)2021

    • Author(s)
      Takuya Hirose*, Shuji Mizumoto*, Ayana Hashimoto, Yuki Takahashi, Takahiro Yoshizawa, Yuko Nitahara-Kasahara, Naoki Takahashi, Jun Nakayama, Kazushige Takehana, Takashi Okada, Yoshihiro Nomura, Shuhei Yamada, Tomoki Kosho, Takafumi Watanabe (*equal contribution)
    • Journal Title

      Glycobiology

      Volume: 31 Issue: 2 Pages: 137-150

    • DOI

      10.1093/glycob/cwaa058

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07054, KAKENHI-PROJECT-19K08745, KAKENHI-PROJECT-19H03616
  • [Journal Article] An Overview of in vivo Functions of Chondroitin Sulfate and Dermatan Sulfate Revealed by Their Deficient Mice2021

    • Author(s)
      Shuji Mizumoto, Shuhei Yamada
    • Journal Title

      Frontiers in Cell and Developmental Biology

      Volume: 9 Pages: 764781-764781

    • DOI

      10.3389/fcell.2021.764781

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07054, KAKENHI-PROJECT-19H03616
  • [Journal Article] Congenital Disorders of Deficiency in Glycosaminoglycan Biosynthesis2021

    • Author(s)
      Shuji Mizumoto, Shuhei Yamada
    • Journal Title

      Frontiers in Genetics

      Volume: 12 Pages: 717535-717535

    • DOI

      10.3389/fgene.2021.717535

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07054, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-21K06552
  • [Journal Article] Quantification of type I collagen α1 in culture medium using nano-liquid chromatography tandem mass spectrometry2021

    • Author(s)
      Ao Gong、Kazuo Yamada、Li Jing、Haruo Takeshita、Ken-ichi Matsumoto
    • Journal Title

      Shimane J Med Sci

      Volume: 38 Pages: 1-5

    • NAID

      130008106018

    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Journal Article] Delineation of musculocontractural Ehlers?Danlos Syndrome caused by dermatan sulfate epimerase deficiency2020

    • Author(s)
      Lautrup Charlotte K.、Teik Keng W.、Unzaki Ai、Mizumoto Shuji、Syx Delfien、Sin Heng H.、Nielsen Irene K.、Markholt Sara、Yamada Shuhei、Malfait Fransiska、Matsumoto Naomichi、Miyake Noriko、Kosho Tomoki
    • Journal Title

      Molecular Genetics & Genomic Medicine

      Volume: 8 Issue: 5

    • DOI

      10.1002/mgg3.1197

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-19K07054
  • [Journal Article] Specific functions of Exostosin-like 3 (EXTL3) gene products2020

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Cellular & Molecular Biology Letters

      Volume: 25 Issue: 1 Pages: 39-39

    • DOI

      10.1186/s11658-020-00231-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06670
  • [Journal Article] Congenital Disorders Caused by Defects in Anabolism of Glycosaminoglycans2020

    • Author(s)
      Shuji Mizumoto, Shuhei Yamada
    • Journal Title

      Trends in Glycoscience and Glycotechnology

      Volume: 32 Issue: 186 Pages: E45-E51

    • DOI

      10.4052/tigg.1759.1E

    • NAID

      130007815517

    • ISSN
      0915-7352, 1883-2113
    • Year and Date
      2020-03-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07054, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-18K06670
  • [Journal Article] Congenital Disorders Caused by Defects in Catabolism of Glycosaminoglycans2020

    • Author(s)
      Shuhei Yamada, Shuji Mizumoto
    • Journal Title

      Trends in Glycoscience and Glycotechnology

      Volume: 32 Issue: 188 Pages: E127-E133

    • DOI

      10.4052/tigg.1968.1E

    • NAID

      130007879857

    • ISSN
      0915-7352, 1883-2113
    • Year and Date
      2020-07-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07054, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-18K06670
  • [Journal Article] Recent Advances in the Pathophysiology of Musculocontractural Ehlers-Danlos Syndrome2019

    • Author(s)
      Tomoki Kosho, Shuji Mizumoto, Takafumi Watanabe, Takahiro Yoshizawa, Noriko Miyake, Shuhei Yamada
    • Journal Title

      Genes

      Volume: 11 Issue: 1 Pages: 43-43

    • DOI

      10.3390/genes11010043

    • NAID

      120006901092

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07054, KAKENHI-PROJECT-19K08745, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-16K19396
  • [Journal Article] Importance of the Fine Structure of Glycolsaminoglycans2019

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Trends in Glycoscience and Glycotechnology

      Volume: 31

    • NAID

      130007683624

    • Data Source
      KAKENHI-PROJECT-18K06670
  • [Journal Article] Structural alteration of glycosaminoglycan side chains and spatial disorganization of collagen networks in the skin of patients with mcEDS-CHST142019

    • Author(s)
      Takuya Hirose, Naoki Takahashi, Prasarn Tangkawattana, Jun Minaguchi, Shuji Mizumoto, Shuhei Yamada, Noriko Miyake, Shujiro Hayashi, Atsushi Hatamochi, Jun Nakayama, Tomomi Yamaguchi, Ayana Hashimoto, Yoshihiro Nomura, Kazushige Takehana, Tomoki Kosho, and Takafumi Watanabe
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - General Subjects

      Volume: 1863 Issue: 3 Pages: 623-631

    • DOI

      10.1016/j.bbagen.2018.12.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Journal Article] Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus2018

    • Author(s)
      Yusuke Mii, Takayoshi Yamamoto, Ritsuko Takada, Shuji Mizumoto, Makoto Matsuyama, Shuhei Yamada, Shinji Takada, and Masanori Taira
    • Journal Title

      Nature Communications

      Volume: 8 Issue: 1 Pages: 1973-1973

    • DOI

      10.1038/s41467-017-02076-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-17K19418, KAKENHI-PLANNED-24111002, KAKENHI-PROJECT-15K07951, KAKENHI-PUBLICLY-17H05782, KAKENHI-PROJECT-25251026, KAKENHI-PROJECT-15K14532
  • [Journal Article] Defect in dermatan sulfate in urine of patients with Ehlers-Danlos syndrome caused by a CHST14/D4ST1 deficiency2018

    • Author(s)
      Shuji Mizumoto, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Tomomi Yamaguchi, Nobuhiko Okamoto, Noriko Miyake, Shuhei Yamada, and Kazuyuki Sugahara
    • Journal Title

      Clinical Biochemistry

      Volume: 50 Issue: 12 Pages: 670-677

    • DOI

      10.1016/j.clinbiochem.2017.02.018

    • NAID

      120006398760

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-15K07951
  • [Journal Article] Vascular abnormalities in the placenta of Chst14-/- fetuses: implications in the pathophysiology of perinatal lethality of the murine model and vascular lesions in human CHST14/D4ST1 deficiency2018

    • Author(s)
      Takahiro Yoshizawa, Shuji Mizumoto, Yuki Takahashi, Shin Shimada, Kazuyuki Sugahara, Jun Nakayama, Shin’ichi Takeda, Yoshihiro Nomura, Yuko Nitahara-Kasahara, Takashi Okada, Kiyoshi Matsumoto, Shuhei Yamada, and Tomoki Kosho
    • Journal Title

      Glycobiology

      Volume: 28 Issue: 2 Pages: 80-89

    • DOI

      10.1093/glycob/cwx099

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-16K19396, KAKENHI-PROJECT-15K07951
  • [Journal Article] Screening of known disease genes in congenital scoliosis.2018

    • Author(s)
      Takeda K, Kou I, Mizumoto S, Yamada S, Kawakami N, Nakajima M, Otomo N, Ogura Y, Miyake N, Matsumoto N, Kotani T, Sudo H, Yonezawa I, Uno K, Taneichi H, Watanabe K, Shigematsu H, Sugawara R, Taniguchi Y, Minami S, Nakamura M, Matsumoto M; Japan Early Onset Scoliosis Research Group, Watanabe K, Ikegawa S.
    • Journal Title

      Molecular Genetics & Genomic Medicine

      Volume: - Issue: 6 Pages: 966-974

    • DOI

      10.1002/mgg3.466

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10986, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16K08251
  • [Journal Article] Identification of novel LFNG mutations in spondylocostal dysostosis.2018

    • Author(s)
      Otomo N, Mizumoto S, Lu HF, Takeda K, Campos-Xavier B, Mittaz-Crettol L, Guo L, Takikawa K, Nakamura M, Yamada S, Matsumoto M, Watanabe K, Ikegawa S.
    • Journal Title

      Journal of human genetics

      Volume: - Issue: 3 Pages: 261-264

    • DOI

      10.1038/s10038-018-0548-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10986, KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-17K16709
  • [Journal Article] The reduction of heparan sulphate in the glomerular basement membrane does not augment urinary albumin excretion2018

    • Author(s)
      Satoshi Aoki, Akiko Saito-Hakoda, Takeo Yoshikawa, Kyoko Shimizu, Kiyomi Kisu, Susumu Suzuki, Kiyoshi Takagi, Shuji Mizumoto, Shuhei Yamada, Toin H. van Kuppevelt, Atsushi Yokoyama, Taiji Matsusaka, Hiroshi Sato, Sadayoshi Ito, and Akira Sugawara
    • Journal Title

      Nephrology Dialysis Transplantation

      Volume: 33 Issue: 1 Pages: 26-33

    • DOI

      10.1093/ndt/gfx218

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-16K08606, KAKENHI-PROJECT-16K08645, KAKENHI-PROJECT-15K07951, KAKENHI-PROJECT-15K09420, KAKENHI-PROJECT-16K15492, KAKENHI-PROJECT-16H03252
  • [Journal Article] Chondroitin sulfate N-acetylgalactosaminyltransferase-1 (CSGalNAcT-1) deficiency results in a mild skeletal dysplasia and joint laxity.2017

    • Author(s)
      Julia Vodopiutz, Shuji Mizumoto, Ekkehard Lausch, Antonio Rossi, Sheila Unger, Nikolaus Janocha, Rainer Seidl, Susanne Greber-Platzer, Shuhei Yamada, Thomas Muller, Bernd Jilma, Rudolf Ganger, Andrea Superti-Furga, Shiro Ikegawa, Kazuyuki Sugahara, Andreas R. Janecke.
    • Journal Title

      Human Mutation

      Volume: 38 Issue: 1 Pages: 34-38

    • DOI

      10.1002/humu.23070

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07951, KAKENHI-PROJECT-16K08251
  • [Journal Article] Identification of biallelic EXTL3 mutations in a novel type of spondylo-epi-metaphyseal dysplasia2017

    • Author(s)
      *Long Guo, *Nursel H Elcioglu, *Shuji Mizumoto, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Shuhei Yamada, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura, Shiro Ikegawa (equal contribution)
    • Journal Title

      Journal of Human Genetics

      Volume: - Issue: 8 Pages: 797-801

    • DOI

      10.1038/jhg.2017.38

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-17K16710, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H05357, KAKENHI-PROJECT-15K07951
  • [Journal Article] Pathophysiological Significance of Dermatan Sulfate Proteoglycans Revealed by Human Genetic Disorders2017

    • Author(s)
      Shuji Mizumoto, Tomoki Kosho, Shuhei Yamada, Kazuyuki Sugahara
    • Journal Title

      Pharmaceuticals

      Volume: 10 Issue: 2 Pages: 34-34

    • DOI

      10.3390/ph10020034

    • NAID

      120006335578

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Journal Article] Structural analysis of chondroitin and dermatan sulfate in Receptor for Advanced Glycation End-products (RAGE) knockout mice2016

    • Author(s)
      Shuji Mizumoto, Shuhei Yamada, Kazuyuki Sugahara
    • Journal Title

      Bulletin of Research Institute of Meijo University

      Volume: 21 Pages: 209-212

    • NAID

      40020904531

    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Journal Article] Functional validation of novel compound heterozygous variants in B3GAT3 resulting in severe osteopenia and fractures: expanding the disease phenotype.2016

    • Author(s)
      *Florian Job, *Shuji Mizumoto, Laurie Smith, Natario Couser, Ashley Brazil, Howard Saal, Melanie Patterson, Margaret I. Gibson, Sarah Soden, Neil Miller, Isabelle Thiffault, Carol Saunders, Shuhei Yamada, Katrin Hoffmann, Kazuyuki Sugahara, Emily Farrow. (*equal contribution)
    • Journal Title

      BMC Medical Genetics

      Volume: 17 Issue: 1 Pages: 86-86

    • DOI

      10.1186/s12881-016-0344-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07951, KAKENHI-PROJECT-16K08251
  • [Journal Article] Molecular interactions between chondroitin-dermatan sulfate and growth factors/receptors/matrix proteins2016

    • Author(s)
      Shuji Mizumoto, Shuhei Yamada, Kazuyuki Sugahara
    • Journal Title

      Curr. Opin. Struct. Biol.

      Volume: 34 Pages: 35-42

    • DOI

      10.1016/j.sbi.2015.06.004

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K07951, KAKENHI-PUBLICLY-26110719, KAKENHI-PROJECT-25860037
  • [Journal Article] Mutations in biosynthetic enzymes for the protein linker region of chondroitin/dermatan/heparan sulfate cause skeletal and skin dysplasias2015

    • Author(s)
      Shuji Mizumoto, Shuhei Yamada, Kazuyuki Sugahara
    • Journal Title

      BioMed Res. Int.

      Volume: 2015 Pages: 861752-861752

    • DOI

      10.1155/2015/861752

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07951, KAKENHI-PUBLICLY-26110719, KAKENHI-PROJECT-25860037
  • [Journal Article] Catabolism of Chondroitin Sulfate2015

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Cell. Mol. Biol. Lett.

      Volume: 20 Issue: 2 Pages: 196-2212

    • DOI

      10.1515/cmble-2015-0011

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Journal Article] Catabolism of Chondroitin Sulfate2015

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Cellular and Molecular Biology Letters

      Volume: 20

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Journal Article] Human genetic disorders and knockout mice deficient in glycosaminoglycan2014

    • Author(s)
      Shuji Mizumoto, Shuhei Yamada, and Kazuyuki Sugahara
    • Journal Title

      BioMed Research International

      Volume: 2014 Pages: 495764-495764

    • DOI

      10.1155/2014/495764

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590071, KAKENHI-PROJECT-25860037, KAKENHI-PUBLICLY-26110719
  • [Journal Article] Expression of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase involved in chondroitin sulfate synthesis is responsible for pulmonary metastasis2013

    • Author(s)
      Shuji Mizumoto, Moto Watanabe, Shuhei Yamada, Kazuyuki Sugahara
    • Journal Title

      BioMed Research International

      Volume: 2013 Pages: 656319-656319

    • NAID

      120005906914

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Journal Article] Mass preparation of oligosaccharides by hydrolysis of chondroitin sulfate polysaccharides with subcritical water microreaction system2013

    • Author(s)
      Shuhei Yamada, Keiichiro Matsushima, Haruo Ura, Nobuyuki Miyamoto, Kazuyuki Sugahara
    • Journal Title

      Carbohydrate Research

      Volume: 371 Pages: 16-21

    • DOI

      10.1016/j.carres.2013.01.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24110501, KAKENHI-PROJECT-24590071
  • [Journal Article] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences with bioactivities2013

    • Author(s)
      Shuji Mizumoto, Saori Murakoshi, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fukui, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
    • Journal Title

      Glycobiology

      Volume: 23 Issue: 2 Pages: 155-168

    • DOI

      10.1093/glycob/cws137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790066, KAKENHI-PUBLICLY-24110501
  • [Journal Article] Expression of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase involved in chondroitin sulfate synthesis is responsible for pulmonary metastasis2013

    • Author(s)
      Mizumoto, S., Watanabe, M., Yamada, S., and Sugahara, K.
    • Journal Title

      BioMed Research International

      Volume: 2013 Pages: 656319-656319

    • DOI

      10.1155/2013/656319

    • NAID

      120005906914

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066
  • [Journal Article] Specific interaction of the envelope glycoproteins E1 and E2 with liver heparan sulfate involved in the tissue tropismatic infection by hepatitis C virus2012

    • Author(s)
      Kobayashi, F., Yamada, S., Taguwa, S., Naito, S., Tani, H., Matsuura, Y., and Sugahara, K.
    • Journal Title

      Glycoconjugate Journal

      Volume: 29 Issue: 4 Pages: 211-220

    • DOI

      10.1007/s10719-012-9388-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-24790451
  • [Journal Article] Specific interaction of the envelope glycoproteins E1 and E2 with liver heparan sulfate involved in the tissue tropismatic infection by hepatitis C virus2012

    • Author(s)
      Fumi Kobayashi, Shuhei Yamada, Shuhei Taguwa, Chikako Kataoka, Satomi Naito, Yoshiki Hama, Hideki Tani, Yoshiharu Matsuura, Kazuyuki Sugahara
    • Journal Title

      Glycoconjugate Journal

      Volume: 29(4) Pages: 211-220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Journal Article] 新規のコンドロイチン硫酸に特異的な加水分解酵素2012

    • Author(s)
      山田修平
    • Journal Title

      応用糖質科学

      Volume: 2 Pages: 104-110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Journal Article] Hyaluronidases have strong hydrolytic activity toward chondroitin 4-sulfate comparable to that for hyaluronan2012

    • Author(s)
      Tomoko Honda, Tomoyuki Kaneiwa, Shuji Mizumoto, Kazuyuki Sugahara, and Shuhei Yamada
    • Journal Title

      Biomolecules

      Volume: 2 Issue: 4 Pages: 549-563

    • DOI

      10.3390/biom2040549

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Journal Article] 新規のコンドロイチン硫酸に特異的な加水分解酵素2012

    • Author(s)
      山田修平
    • Journal Title

      応用糖質科学

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Journal Article] Identification of amino acid residues required for the substrate specificity of human and mouse chondroitin sulfate hydrolase (conventional hyaluronidase-4)2012

    • Author(s)
      Tomoyuki Kaneiwa, Anzu Miyazaki, Ryo Kogawa, Shuji Mizumoto, Kazuyuki Sugahara, and Shuhei Yamada
    • Journal Title

      Journal of Biological Chemistry

      Volume: 287 Issue: 50 Pages: 42119-42128

    • DOI

      10.1074/jbc.m112.360693

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Journal Article] Unique heparan sulfate from shrimp heads exhibits a strong inhibitory effect on infections by dengue virus and Japanese encephalitis virus2011

    • Author(s)
      Jiancheng Chen, Shuhei Yamada, Yoshiki Hama, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Eunmi Kim, Takashi Kimura, Naonori Takahashid, Kazuya Hidari, Takashi Suzuki, Yasuo Suzuki, Kazuyuki Sugahara
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 412(1) Pages: 136-142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Journal Article] Evolution of Glycosaminoglycans : Comparative Biochemical Study2011

    • Author(s)
      Shuhei Yamada, Kazuyuki Sugahara, Suat Özbek
    • Journal Title

      Communicative & Integrative Biology

      Volume: 4 Pages: 150-158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Journal Article] Unique heparan sulfate from shrimp heads exhibits a strong inhibitory effect on infections by dengue virus and Japanese encephalitis virus2011

    • Author(s)
      Jiancheng Chen, Shuhei Yamada#, Yoshiki Hama, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Eunmi Kim, Takashi Kimura, Naonori Takahashi, Kazuya I. P. J. Hidari, Takashi Suzuki, Yasuo Suzuki, and Kazuyuki Sugahara#
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 412(1) Pages: 136-142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Journal Article] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in α-Thrombomodulin from Human Urine2011

    • Author(s)
      Taishi Hashiguchi, Shuji Mizumoto, Yuko Nishimura, Jun-ichi Tamura, Shuhei Yamada, Kazuyuki Sugahara
    • Journal Title

      Journal of Biological Chemistry

      Volume: 286(38) Pages: 33003-33011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Journal Article] Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain.2011

    • Author(s)
      Akatsu C., Mizumoto S., Kaneiwa T., Maccarana M., Malmstrom A., Yamada S., Sugahara K.
    • Journal Title

      Glycobiology 21(5)

      Pages: 565-574

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] Evolution of Glycosaminoglycans : Comparative Biochemical Study.2011

    • Author(s)
      Yamada S., Sugahara K., Ozbek S.
    • Journal Title

      Commun.Integr.Biol. (in press.)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] Demonstration of the Hepatocyte Growth Factor Signaling Pathway in the in vitro Neuritogenic Activity of Chondroitin Sulfate from Ray Fish Cartilage2011

    • Author(s)
      Taishi Hashiguchi, Takanari Kobayashi, Duriya Fongmoon, Ajaya Kumar Shetty, Shuji Mizumoto, Nobuyuki Miyamoto, Toshikazu Nakamura, Shuhei Yamada#, and Kazuyuki Sugahara#
    • Journal Title

      Biochim. Biophys. Acta

      Volume: 1810(4) Pages: 406-413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Journal Article] Paradoxical effects of chondroitin sulfate-E on Japanese encephalitis viral infection2011

    • Author(s)
      Eunmi Kim, Megumi Okumura, Hirofumi Sawa, Tadaaki Miyazaki, Daisuke Fujikura, Shuhei Yamada, Kazuyuki Sugahara, Michihito Sasaki, Takashi Kimura
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 409(4) Pages: 717-722

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Journal Article] Involvement of HNK-1 sulfotransferase in the biosynthesis of chondro itin sulfate and the GlcA(3-O-sulfate)-Gal-Gal-Xyl tetrasaccharide found in α-thrombomodulin from human urine2011

    • Author(s)
      Taishi Hashiguchi
    • Journal Title

      J.Biol.Chem

      Volume: 286 Issue: 38 Pages: 33003-33011

    • DOI

      10.1074/jbc.m111.279174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057, KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066
  • [Journal Article] Demonstration of the hepatocyte growth factor signaling pathway in the in vitro neuritogenic activity of chondroitin sulfate from ray fish cartilage2011

    • Author(s)
      Taishi Hashiguchi
    • Journal Title

      Bionchim.Biophys.Acta

      Volume: 1810 Issue: 4 Pages: 406-413

    • DOI

      10.1016/j.bbagen.2011.01.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057, KAKENHI-PROJECT-23390016
  • [Journal Article] Unique heparan sulfate from shrimp heads exhibits a strong inhibitory effect on infections by dengue virus and Japanese encephalitis virus2011

    • Author(s)
      Jiancheng Chen
    • Journal Title

      Biochem.Biophys.Res.Commun

      Volume: 412 Issue: 1 Pages: 136-142

    • DOI

      10.1016/j.bbrc.2011.07.059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057, KAKENHI-PROJECT-23390016
  • [Journal Article] Paradoxical effects of chondroitin sulfate-E on Japanese encephalitis viral infection2011

    • Author(s)
      Kim, E., Okumura, M., Sawa, H., Miyazaki, T., Fujikura, D., Yamada, S., Sugahara, K., Sasaki, M., Kimura, T.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 409 Issue: 4 Pages: 717-722

    • DOI

      10.1016/j.bbrc.2011.05.072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790317
  • [Journal Article] Demonstration of the Hepatocyte Growth Factor Signaling Pathway in the in vitro Neuritogenic Activity of Chondroitin Sulfate from Ray Fish Cartilage.2011

    • Author(s)
      Hashiguchi Y., Kobayashi T., Fongmoon D., Shetty A.K., Mizumoto S., Miyamoto N., Nakamura T., Yamada S., Sugahara K.
    • Journal Title

      Biochim.Biophys.Acta 1810(4)

      Pages: 406-413

    • NAID

      120002934270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] Evolution of Glycosaminoglycans: Comparative Biochemical Study2011

    • Author(s)
      Shuhei Yamada#, Kazuyuki Sugahara, and Suat Ozbek
    • Journal Title

      Commun. Integr. Biol

      Volume: 4(2) Pages: 150-158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Journal Article] Evolution of glycosaminoglycans: comparative biochemical study.2011

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Commun. Integr. Biol.

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Journal Article] Demonstration of the hepatocyte growth factor signaling pathway in the in vitro neuritogenic activity of chondroitin sulfate from ray fish cartilage2011

    • Author(s)
      Taishi Hashiguchi, Takanari Kobayashi, Duriya Fongmoon, Ajaya Kumar Shetty, Shuji Mizumoto, Nobuyuki Miyamoto, Toshikazu Nakamura, Shuhei Yamada, Kazuyuki Sugahara
    • Journal Title

      Biochimica et Biophysica Acta (General Subjects)

      Volume: 1810(4) Pages: 406-413

    • NAID

      120002934270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Journal Article] Involvement of HNK-1 sulfotransferase in the biosynthesis of the GlcUA(3-O-sulfate)-Gal-Gal-Xyl tetrasaccharide found in ?-thrombomodulin from human urine2011

    • Author(s)
      Taishi Hashiguchi, Shuji Mizumoto, Yuko Nishimura, Jun-ichi Tamura, Shuhei Yamada#, and Kazuyuki Sugahara#
    • Journal Title

      J. Biol. Chem

      Volume: 286(38) Pages: 33003-33011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Journal Article] Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain2011

    • Author(s)
      Chizuru Akatsu, Shuji Mizumoto, Tomoyuki Kaneiwa, Marco Maccarana, Anders Malmström, Shuhei Yamada, Kazuyuki Sugahara
    • Journal Title

      Glycobiology

      Volume: 21(5) Pages: 565-574

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Journal Article] Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain2011

    • Author(s)
      Akatsu, C., Mizumoto, S., Kaneiwa, T., Maccarana, M., Malmstrom,. A., Yamada, S., Sugahara, K.
    • Journal Title

      Glycobiology

      Volume: 21 Issue: 5 Pages: 565-574

    • DOI

      10.1093/glycob/cwq208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Journal Article] Evolution of Glycosaminoglycans : Comparative Biochemical Study.2010

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Communicative & Integrative Biology

      Volume: In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] Identification of Human Hyaluronidase-4 as a Novel Chondroitin Sulfate Hydrolase That Preferentially Cleaves the Galactosaminidic Linkage in the Trisulfated Tetrasaccharide Sequence2010

    • Author(s)
      Tomoyuki Kaneiwa, Shuji Mizumoto, Kazuyuki Sugahara, and Shuhei Yamada#
    • Journal Title

      Glycobiology

      Volume: 20(3) Pages: 300-309

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Journal Article] Development of a Mouse Monoclonal Antibody Against the Chondroitin Sulfate-protein Linkage Region Derived from Shark Cartilage2010

    • Author(s)
      Chizuru Akatsu, Duriya Fongmoon, Shuji Mizumoto, Jean-Claude Jacquinet, Prachya Kongtawelert, Shuhei Yamada#, and Kazuyuki Sugahara#
    • Journal Title

      Glycoconjugate J

      Volume: 27(4) Pages: 387-399

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Journal Article] Analysis of the structure and neuritogenic activity of chondroitin sulfate/dermatan sulfate hybrid chains from porcine fetal membranes.2010

    • Author(s)
      Hashiguchi T., Mizumoto S., Yamada S., Sugahara K.
    • Journal Title

      Glycoconjugate J. 27(1)

      Pages: 49-60

    • NAID

      120004043734

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] A non-sulfated chondroitin stabilizes membrane tubulation in cnidarian organelles.2010

    • Author(s)
      Adamczyk P., Zenkert C., Balasubramanian P.G., Yamada S., Murakoshi S., Sugahara K., Hwang J.S., Gojobori T., Holstein T.W., Ozbek S.
    • Journal Title

      J.Biol.Chem. 285(33)

      Pages: 25613-25623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] Loss-of-function mutations of CHST14 in a new type of Ehlers-Danlos syndrome.2010

    • Author(s)
      Miyake N., Kosho T., Mizumoto S., Furuichi T., Hatamochi A., Nagashima Y., Arai E., Takahashi K., Kawamura R., Wakui K., Takahashi J., Kato H., Yasui H., Ishida T., Ohashi H., Nishimura G., Shiina M., Saitsu H., Tsurusaki Y., Doi H., Fukushima Y., Ikegawa S., Yamada S., Sugahara K., Matsumoto N.
    • Journal Title

      Hum.Mutat.(Equal contribution) 31(8)

      Pages: 966-974

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] Involvement of chondroitin sulfate E in the liver tumor focal formation of murine osteosarcoma cells.2009

    • Author(s)
      Basappa Murugan S., Sugahara K.N., Lee C.M., ten Dam G.B., van Kuppevelt T.H., Miyasaka M., Yamada S., Sugahara K.
    • Journal Title

      Glycobiology 19(7)

      Pages: 735-742

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] Structural and Functional Changes of Sulfated Glycosaminoglycans in Xenopus laevis during Embryogenesis2009

    • Author(s)
      Shuhei Yamada, Masako Onishi, Reiko Fujinawa, Yuko Tadokoro, Koji Okabayashi, Makoto Asashima, and Kazuyuki Sugahara,
    • Journal Title

      Glycobiology (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Journal Article] Structural and functional changes of sulfated glycosaminoglycans in Xenopus laevis during embryogenesis.2009

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Glycobiology 19

      Pages: 488-498

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Journal Article] Chondroitin Hydrolase in Caenorhabditis elegans.2009

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Trends Glycosci.Glycotechnol. 21

      Pages: 149-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] Isolation and Characterization of a Novel Chondroitin Sulfate from Squid LiverIntegument Rich in N-Acetylgalactosamine(4, 6-O-disulfate) and Glucuronate(3-O-sulfate) Residues2009

    • Author(s)
      Ajaya Kumar Shetty, Takanari Kobayashi, Shuji Mizumoto, Masaki Narumi, YoshiakiKudo, Shuhei Yamada#, and Kazuyuki Sugahara#
    • Journal Title

      Carbohydr. Res

      Volume: 344(12) Pages: 1526-1532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Journal Article] Chondroitin Hydrolase in Caenorhabditis elegans.2009

    • Author(s)
      Yamada S., Mizumoto S., Sugahara K.
    • Journal Title

      Trends Glycosci.Glycotechnol. 21(119)

      Pages: 149-162

    • NAID

      10026976542

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] Structural and Functional Changes of Sulfated Glycosaminoglycans in Xenopus laevis during Embryogenesis2009

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Glycobiology (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Journal Article] Structural and Functional Changes of Sulfated Glycosaminoglycans in Xenopus laevis during Embryogenesis2009

    • Author(s)
      Yamada S., Onishi M., Fujinawa R., Tadokoro Y., Okabayashi K., Asashima M., Sugahara K.
    • Journal Title

      Glycobiology 19(5)

      Pages: 488-498

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] Isolation and Characterization of a Novel Chondroitin Sulfate from Squid Liver Integument Rich in N-Acetylgalactosamine(4,6-O-disulfate) and Glucuronate(3-O-sulfate) Residues2009

    • Author(s)
      Ajaya Kumar Shetty, Takanari Kobayashi, Shuji Mizumoto, Masaki Narumi, Yoshiaki Kudo, Shuhei Yamada, and Kazuyuki Sugahara
    • Journal Title

      Carbohydr. Res. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Journal Article] Structural and functional changes of sulfated glycosaminoglycans in Xenopus laevis during embryogenesis.2009

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Glycobiology 19

      Pages: 488-498

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] Chondroitin Hydrolase in Caenorhabditis elegans2009

    • Author(s)
      huhei Yamada#, Shuji Mizumoto, and Kazuyuki Sugahara
    • Journal Title

      Trends Glycosci. Glycotechnol

      Volume: 21(119) Pages: 149-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Journal Article] Important role of heparan sulfate in postnatal islet growth and insulin secretion.2009

    • Author(s)
      Takahashi I., Noguchi N., Nata K., Yamada S., Kaneiwa T., Mizumoto S., Ikeda T., Sugihara K., Asano M., Yoshikawa T., Yamauchi A., Shervani N. J., Uruno A., Kato I., Unno M., Sugahara K., Takasawa S., Okamoto H., Sugawara A.
    • Journal Title

      Biochem.Biophys.Res.Commun. 383(1)

      Pages: 113-118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] Structural and Functional Changes of Sulfated Glycosaminoglycans in Xenopus laevis during Embryogenesis2009

    • Author(s)
      huhei Yamada#, Masako Onishi, Reiko Fujinawa, Yuko Tadokoro, Koji Okabayashi, Makoto Asashima, and Kazuyuki Sugahara
    • Journal Title

      Glycobiology

      Volume: 19(5) Pages: 488-498

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Journal Article] Chondroitin Hydrolase in Caenorhabditis elegans.2009

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Trends Glycosci. Glycotechnol. 21

      Pages: 149-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Journal Article] Structural and Functional Changes of Sulfated Glycosaminoglycans in Xenopus laevis during Embryogenesis.2009

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Glycobiology (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] Isolation and characterization of a novel chondroitin sulfate from squid liver integument rich in N-acetylgalactosamine(4,6-O-disulfate) and glucuronate(3-O-sulfate) residues.2009

    • Author(s)
      Shetty A.K., Kobayashi T., Mizumoto S., Narumi M., Kudo Y., Yamada S., Sugahara K.
    • Journal Title

      Carbohydr.Res.(Equal contribution) 344(12)

      Pages: 1526-1532

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Journal Article] Important Role of Heparan Sulfate in Postnatal Islet Growth and Insulin Secretion2009

    • Author(s)
      Iwao Takahashi, Naoya Noguchi, Koji Nata, Shuhei Yamada, Tomoyuki Kaneiwa, Shuji Mizumoto, Takayuki Ikeda, Kazushi Sugihara, Masahide Asano, Takeo Yoshikawa, Akiyo Yamauchi, Nausheen Jamal Shervani, Akira Uruno, Ichiro Kato, Michiaki Unno, Kazuyuki Sugahara, Shin Takasawa, Hiroshi Okamoto, and Akira Sugawara
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 383(1) Pages: 113-118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Journal Article] Identification of a novel chondroitin hydrolase in Caenorhabditis elegans.2008

    • Author(s)
      Kaneiwa, T., Yamada, S., Mizumoto, S., Montano, A. M., Mitani, S., and Sugahara, K.
    • Journal Title

      J Biol. Chem. 283(22)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Journal Article] Determination ofIduronic Acid and Glucuronic Acid in SulfatedChondroitin/Dermatan Hybrid Chains by1H-Nuclear Magnetic Resonance Spectroscopy.*These authors contributed equally to the work.2008

    • Author(s)
      Fuchuan Li, Shuhei Yamada, Basappa, Ajaya K. Shetty, Makiko Sugiura, and Kazuyuki Sugahara
    • Journal Title

      Glycoconjugate J. 25

      Pages: 603-610

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Journal Article] Determination of Iduronic Acid and Glucuronic Acid in Sulfated Chondroitin/Dermatan Hybrid Chains by 1H-Nuclear Magnetic Resonance Spectroscopy.2008

    • Author(s)
      Li, F., Yamada, S., Basappa, Shetty, A. K., Sugiura, M., and Sugahara, K.
    • Journal Title

      Glycoconjugate J. (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Journal Article] Potential Therapeutic Application of Chondroitin Sulfate/Dermatan Sulfate2008

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Current Drug Discovery Technologies 5

      Pages: 289-301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Journal Article] Identificationof a Novel Chondroitin Hydrolase inCaenorhabditis elegans. These authorscontributed equally to the work2008

    • Author(s)
      Tomoyuki Kaneiwa, Shuhei Yamada, Shuji Mizumoto, Adriana M. Montano, Souhei Mitani and Kazuyuki Sugahara
    • Journal Title

      J. Biol. Chem. 283

      Pages: 14971-14979

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Journal Article] Potential Therapeutic Application ofChondroitin Sulfate/Dermatan Sulfate2008

    • Author(s)
      Shuhei Yamada and Kazuyuki Sugahara
    • Journal Title

      Current Drug Discovery Technologies 5

      Pages: 289-301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Journal Article] Glycosaminoglycans in Hydra magnipapillata (Hydrozoa, Cnidaria): demonstration of chondroitin in the developing nematocyst, sting organelle, and structural characterization of glycosaminoglycans.2007

    • Author(s)
      Yamada, S., Morimoto, H., Fujisawa, T., and Sugahara, K.
    • Journal Title

      Glycobiology 17(8)

      Pages: 886-894

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Journal Article] Novel sulfated octa- and decasaccharides from squid cartilage chondroitin sulfate-E: Sequencing and their application for determination of the epitope structure of monoclonal antibody MO-2252007

    • Author(s)
      Deepa, S. S., Kalayanamitra, K, Ito, Y., Kongtawelert, P, Fukui, S., Yamada, S., Mikami, T., and Sugahara, K.
    • Journal Title

      Biochemistry 46(9)

      Pages: 2453-2465

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Journal Article] Structural determination of novel sulfated octasaccharides isolated from chondroitin sulfate of shark cartilage and their application for characterizing monoclonal antibody epitopes2007

    • Author(s)
      Sarama S.Deepa, Shuhei Yamada, Shigeyuki Fukui, Kazuyuki Sugahara
    • Journal Title

      Glycobiology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590078
  • [Journal Article] Novel sulfated octa-and decasaccharides from squid cartilage chondroitin sulfate-E : Sequencing and application for determination of the epitope structure of monoclonal antibody MO-225.2007

    • Author(s)
      Sarama Sathyaseelan Deepa, Kittiwan Kalayanamitra, Yumi Ito, Prachya Kongtaweelert, Shigeyuki Fukui, Shuhei Yamada, Tadahisa Mikami, Kazuyuki Sugahara
    • Journal Title

      Biochemistry 46 (9)

      Pages: 2453-2465

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590078
  • [Journal Article] Glycosaminoglycans in Hydra magnipapillata(Hydrozoa, Cnidaria): demonstration of chondroitin in the developing nematocyst, sting organelle, and structural characterization of glycosaminoglycans.2007

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Glycobiology 17

      Pages: 886-894

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Journal Article] Chondroitinase-mediatedDegradation of Rare 3-O-Sulfated GlucuronicAcid in Functional Oversulfated Chondroitin Sulfate K and E.2007

    • Author(s)
      Duriya Fongmoon, Ajaya Kumar Shetty, Basappa, Shuhei Yamada, Makiko Sugiura,Prachya Kongtawelert, and Kazuyuki Sugahara
    • Journal Title

      J. Biol. Chem. 282

      Pages: 36895-36904

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Journal Article] Defective A-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular develonment2007

    • Author(s)
      Alexandra Abramsson, Sindhulakshmi Kurup, Marta Busse, Shuhei Yamada, Per Lindblom, Edith Schallmeiner, Denise Stenzel, Dominique Sauvaget, Johan Ledin, Maria Ringvall, Ulf Landegren, Lena Kjellen, GOran Bondjers, Jin-ping Li, Ulf Lindahl, Dorothe Spillmann, Christer Betsholtz, Holger Gerhardt
    • Journal Title

      Genes Dev. 21(3)

      Pages: 316-331

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590078
  • [Journal Article] Glycosaminoglycans in Hydra magnipapillata(Hydrozoa, Cnidaria) : Demonstration ofChondroitin in the Developing Nematocyst,Sting Organelle, and Structural Characterization of Glycosaminoglycans2007

    • Author(s)
      Shuhei Yamada, Hideto Morimoto, ToshitakaFujisawa, and Kazuyuki Sugahara
    • Journal Title

      Glycobiology 17

      Pages: 886-894

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Journal Article] StructuralDetermination of Novel SulfatedOctasaccharides Isolated from ChondroitinSulfate of Shark Cartilage and TheirApplication for Characterizing MonoclonalAntibody Epitopes.2007

    • Author(s)
      Sarama S. Deepa, Shuhei Yamada, Shigeyuki Fukui, and Kazuyuki Sugahara
    • Journal Title

      Glycobiology 17

      Pages: 631-645

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Journal Article] Structural Determination of Novel Sulfated Octasaccharides Isolated from Chondroitin Sulfate of Shark Cartilage and Their Application for Characterizing Monoclonal Antibody Epitopes.2007

    • Author(s)
      Deepa, S. S., Yamada, S., Fukui, S., and Sugahara, K.
    • Journal Title

      Glycobiology 17(6)

      Pages: 631-645

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Journal Article] Chondroitinase-mediated degradation of rare 3-O-sulfated glucuronic acid in functional oversulfated chondroitin sulfate K and E.2007

    • Author(s)
      Fongmoon, D., Shetty, A. K., Basappa, Yamada, S., Sugiura, M., Kongtawelert, P., and Sugahara, K.
    • Journal Title

      J. Biol. Chem. 282(51)

      Pages: 36895-36904

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Journal Article] Glycosaminoglycans in Hydra magnipapillata (Hydrozoa, Cnidaria): demonstration of chondroitin in the developing nematocyst, sting organelle, and structural characterization of glycosaminoglycans.2007

    • Author(s)
      Yamada, S.
    • Journal Title

      Glycobiology 17

      Pages: 886-894

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Journal Article] Glycosaminoglycans in Hydra magnipapillata(Hydrozoa, Cnidaria): demonstration of chondroitin in the developing nematocyst, sting organelle, and structural characterization of glycosaminoglycans.2007

    • Author(s)
      Yamada, S.
    • Journal Title

      Glycobiology 17

      Pages: 886-894

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Journal Article] Preface for the Special Issue Entitled The research front line of the biosynthesis and recognition of acidic sugar chains.2006

    • Author(s)
      Shuhei Yamada, Akira Seko
    • Journal Title

      Trends Glycosci.Glycotech. 18(101)

      Pages: 163-164

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590078
  • [Journal Article] Preface for the Special Issue Entitled "The research front line of the biosynthesis and recognition of acidic sugar chains".2006

    • Author(s)
      Shuhei Yamada
    • Journal Title

      Trends in Glycoscience and Glycotechnology 18・101

      Pages: 163-164

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590078
  • [Journal Article] Heparin-binding Growth Factor, Pleiotrophin, Mediates Neuritogenic Activity of Embryonic Pig Brain-derived Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains toward Embryonic Mouse Hippocampal Neurons in Culture.2005

    • Author(s)
      Xingfeng Bao, Tadahisa Mikami, Shuhei Yamada, Andreas Faissner, Takashi Muramatsu, Kazuyuki Sugahara
    • Journal Title

      J.Biol.Chem. 280(10)

      Pages: 9180-9191

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590078
  • [Journal Article] Chondroitin Sulfate Characterized by the E-disaccharide Unit Is a Potent Inhibitor of Herpes Simplex Virus Infectivity and Provides the Virus Binding Sites on gro2C Cells.2005

    • Author(s)
      Kicki Bergefall, Edward Trybala, Maria Johansson, Toni Uyama, Satomi Naito, Shuhei Yamada, Hiroshi Kitagawa, Kazuyuki Sugahara, Tomas Bergstrom
    • Journal Title

      J.Biol.Chem. 280(37)

      Pages: 32193-32199

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590078
  • [Journal Article] Embryonic Fibrobasts with a Gene Trap Mutation in Ext1 Produce Short Heparan Sulfate Chains.2004

    • Author(s)
      Shuhei Yamada
    • Journal Title

      J.Biol.Chem. 279・31

      Pages: 32134-32141

    • Data Source
      KAKENHI-PROJECT-15790056
  • [Journal Article] Determination of the glycosaminoglycan-protein linkage region oligosaccharide structure of proteoglycans from Drosophila melanogaster and Caenorhabditis elegans.2002

    • Author(s)
      山田 修平
    • Journal Title

      J.Biol.Chem. 277(35)

      Pages: 31877-31886

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13470493
  • [Journal Article] Determination of the glycosaminoglycan-protein linkage region oligosaccharide structures of proteoglycans from Drosophila melanogaster and Caenorhabditis elegans.2002

    • Author(s)
      Yamada, Shuhei
    • Journal Title

      J.Biol.Chem. 277(35)

      Pages: 31877-31886

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13470493
  • [Patent] コンドロイチン硫酸オリゴ糖の製造方法2012

    • Inventor(s)
      松嶋景一郎,浦晴雄,鎌田樹志,宮本宜之,菅原一幸,山田修平
    • Industrial Property Rights Holder
      地方独立行政法人北海道立総合研究機構,丸共水産株式会社,国立大学法人北海道大学
    • Industrial Property Number
      2012-035546
    • Filing Date
      2012-02-21
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Patent] コンドロイチン硫酸オリゴ糖の製造方法2012

    • Inventor(s)
      松嶋景一郎, 浦晴雄, 鎌田樹志, 宮本宜之, 菅原一幸, 山田修平
    • Industrial Property Rights Holder
      地方独立行政法人北海道立総合研究機構, 丸共水産株式会社, 国立大学法人北海道大学
    • Industrial Property Number
      2012-035546
    • Filing Date
      2012-02-21
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Patent] グリコサミノグリカン分解促進剤2009

    • Inventor(s)
      菅原一幸, 山田修平, 水本秀二, 金岩知之
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2009-238490
    • Filing Date
      2009-10-15
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Patent] グリコサミノグリカン分解促進剤2009

    • Inventor(s)
      菅原一幸,山田修平,水本秀二,金岩知之
    • Industrial Property Rights Holder
      国立大学法人北海道大学
    • Industrial Property Number
      2009-238490
    • Filing Date
      2009-10-15
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Patent] グリコサミノグリカン分解促進剤2009

    • Inventor(s)
      菅原一幸, 山田修平, 水本秀二, 金岩知之
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2009-238490
    • Filing Date
      2009-10-15
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Patent] グリコサミノグリカン分解促進剤2009

    • Inventor(s)
      菅原一幸、山田修平、水本秀二、金岩知之
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2009-238490
    • Filing Date
      2009-10-15
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Patent] ムコ多糖分解促進剤2007

    • Inventor(s)
      菅原一幸, 山田修平, 水本秀二
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2007-291424
    • Filing Date
      2007-11-09
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Patent] ムコ多糖分解促進剤2007

    • Inventor(s)
      菅原一幸, 山田修平, 水本秀二
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2007-11-09
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Patent] ムコ多糖分解促進剤2007

    • Inventor(s)
      菅原一幸, 山田修平, 水本秀二
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2007-291424
    • Filing Date
      2007-11-09
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Presentation] グリコサミノグリカン生合成に関わるキシロース転移酵素の遺伝性疾患を発症する変異型の酵素活性測定2024

    • Author(s)
      野原若菜、清益慎也、山田修平、水本秀二
    • Organizer
      日本薬学会第144回年会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] Hereditary bone disorders caused by reduced activity of xylosyltransferases involved in glycosaminoglycan biosynthesis2023

    • Author(s)
      Shuhei Yamada, Asaka Takayasu, Shinya Kiyomasu, Shuji Mizumoto
    • Organizer
      The 26th International Glycoconjugate Symposium (Glyco26)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] 脳のグルタミン酸作動性神経特異的にヘパラン硫酸生合成酵素Extl3を欠損させたマウスにおける脳機能解析2023

    • Author(s)
      沼崎礼奈、三河範花、髙羽里佳、衣斐大祐、水本秀二、平松正行、菅原明、山田修平
    • Organizer
      糖鎖科学中部拠点 第18回若手の力 フォーラム
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] Glycosaminoglycan structure in congenital disorders caused by defects in its biosynthetic enzymes2023

    • Author(s)
      Shuhei Yamada
    • Organizer
      International conference of Proteoglycans in cancer and embryonic development
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] デビュクオア骨異形成症や脊椎・眼症候群を引き起こすキシロース転移酵素のアミノ酸置換による酵素活性への影響2023

    • Author(s)
      水本秀二、清益慎也、山田修平
    • Organizer
      日本薬学会第143回年会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] グルタミン酸作動性神経特異的にヘパラン硫酸(HS)合成酵素EXTL3を欠損させたマウス脳におけるHS、Extl3の発現解析2023

    • Author(s)
      沼崎礼奈、髙羽里佳、衣斐大祐、水本秀二、平松正行、菅原明、山田修平
    • Organizer
      第69回日本薬学会東海支部総会・大会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] 遺伝性骨疾患を引き起こすキシロース転移酵素の変異による酵素活性への影響2023

    • Author(s)
      水本秀二、清益慎也、山田修平
    • Organizer
      糖鎖科学中部拠点 第18回若手の力 フォーラム
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] Effect of uridine diphosphate on the enzymatic activities of glycosaminoglycan biosynthetic enzymes, xylosyl- and glucuronyl-transferases2023

    • Author(s)
      Asaka Takayasu, Shuhei Yamada, Shuji Mizumoto
    • Organizer
      The 26th International Glycoconjugate Symposium (Glyco26)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] Effect of uridine diphosphate on the enzymatic activities of UDP-GlcA decarboxylase, xylosyltransferase, and glucuronyltransferase20232023

    • Author(s)
      Shuji Mizumoto, Asaka Takayasu, Kenji Furukawa, Shuhei Yamada
    • Organizer
      Annual Meeting of Society for Glycobiology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] グルタミン酸作動性神経特異的にヘパラン硫酸生合成酵素Extl3を完全欠損させたマウスの解析2023

    • Author(s)
      荻堂百佳、髙羽里佳、衣斐大祐、水本秀二、平松正行、菅原 明、山田修平
    • Organizer
      第55回日本結合組織学術大会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] 糸球体たこ足細胞特異的にヘパラン硫酸生合成酵素EXTL3を欠損させたマウスにおけるヘパラン硫酸の解析2023

    • Author(s)
      石垣凜空馬、村松 尚、水本秀二、松阪泰二、菅原 明、山田修平
    • Organizer
      第69回日本薬学会東海支部総会・大会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] T細胞特異的にヘパラン硫酸生合成酵素Extl3を欠損させたマウスにおけるT細胞分化の解析2023

    • Author(s)
      浅岡千晶、山﨑奈都、水本秀二、山下匡、菅原明、山田修平
    • Organizer
      糖鎖科学中部拠点 第18回若手の力 フォーラム
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] ウリジン二リン酸(UDP)によるUDP-グルクロン酸デカルボキシラーゼ、キシロース転移酵素およびグルクロン酸転移酵素活性への影響2023

    • Author(s)
      水本秀二、髙安麻香、古川憲司、山田修平
    • Organizer
      糖鎖科学中部拠点 第19回若手の力フォーラム
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] Analysis of T cell differentiation in mice lacking heparan sulfate biosynthetic enzyme Extl32023

    • Author(s)
      Chiaki Asaoka, Natsu Yamazaki, Shuji Mizumoto, Tadashi Yamashita, Akira Sugawara, Shuhei Yamada
    • Organizer
      The 26th International Glycoconjugate Symposium (Glyco26)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] グリコサミノグリカン生合成に関わるキシロース転移酵素の遺伝性疾患を引き起こす変異が及ぼす酵素活性への影響2022

    • Author(s)
      清益慎也、花立妃子、伊藤有美、山田修平、水本秀二
    • Organizer
      日本薬学会第142回年会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] ヘパラン硫酸生合成酵素EXTL3をT細胞特異的に欠損させたマウスの解析2022

    • Author(s)
      山﨑奈都、大橋礼、大橋里帆、水本秀二、山下匡、菅原明、山田修平
    • Organizer
      日本薬学会第142回年会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] Biosynthesis of glycosaminoglycans and the related congenital disorders2022

    • Author(s)
      Shuhei Yamada
    • Organizer
      6th International Anatomical Sciences and Cell Biology Conference (IASCBC)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] グリコサミノグリカン生合成に関わるキシロース転移酵素1および2の遺伝性疾患を引き起こす変異が及ぼす酵素活性への影響2022

    • Author(s)
      清益慎也、花立妃子、伊藤有美、山田修平、水本秀二
    • Organizer
      糖鎖科学中部拠点 第17回若手の力 フォーラム
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] T細胞特異的EXTL3欠損マウスにおけるT細胞分化の遅延2022

    • Author(s)
      山﨑奈都、大橋礼、大橋里帆、水本秀二、山下匡、菅原明、山田修平
    • Organizer
      第86回日本生化学会中部支部例会・シンポジウム
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] グリコサミノグリカンの結合領域四糖の生合成に関わるb3galt6をノックアウトしたゼブラフィッシュの機能解析2022

    • Author(s)
      水本秀二、Sarah Delbaere、Adelbert De Clercq、Fredrik Noborn、Jan Willem Bek、Lien Alluyn、Charlotte Gistelinck、Delfien Syx、Phil L. Salmon、Paul J. Coucke、Goran Larson、山田修平、Andy Willaert、Fransiska Malfait
    • Organizer
      糖鎖科学中部拠点 第17回若手の力 フォーラム
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] 興奮性神経特異的にヘパラン硫酸生合成酵素Extl3を欠損させたマウスの解析2022

    • Author(s)
      三河範花、小林素子、石崎愛弓、髙羽里佳、衣斐大祐、水本秀二、平松正行、菅原明、山田修平
    • Organizer
      第54回日本結合組織学術大会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] Biosynthesis of glycosaminoglycans and the related congenital disorders2022

    • Author(s)
      Shuhei Yamada
    • Organizer
      6th International Anatomical Sciences and Cell Biology Conference (IASCBC) (Singapore)
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] Congenital disorders daused by defects in biosynthesis of glycosaminoglycans2022

    • Author(s)
      Shuhei Yamada
    • Organizer
      2022 Korea - Japan Joint Symposium on Matrix Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] 遺伝性の骨系統疾患を引き起こす変異型キシロース転移酵素の酵素活性への影響2022

    • Author(s)
      水本秀二、清益慎也、山田修平
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] β3ガラクトース転移酵素6 (b3galt6) のゼブラフィッシュ変異体におけるコンドロイチン/デルマタン/ヘパラン硫酸の定量解析2022

    • Author(s)
      水本秀二、Sarah Delbaere、Adelbert De Clercq、Fredrik Noborn、Jan Willem Bek、Lien Alluyn、Charlotte Gistelinck、Delfien Syx、Phil L. Salmon、Paul J. Coucke、Goran Larson、山田修平、Andy Willaert、Fransiska Malfait
    • Organizer
      日本薬学会第142回年会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] ヘパラン硫酸生合成酵素Extl3を興奮性神経特異的に欠損させたマウスにおける認知機能と不安様行動の解析2022

    • Author(s)
      三河範花、髙羽里佳、小林素子、石崎愛弓、衣斐大祐、水本秀二、平松正行、菅原明、山田修平
    • Organizer
      日本薬学会第142回年会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] グリコサミノグリカンの結合領域四糖の生合成に関わるb3galt6をノックアウトしたゼブラフィッシュにおけるコンドロイチン/デルマタン/ヘパラン硫酸の定量解析2021

    • Author(s)
      Sarah Delbaere、Adelbert De Clercq、水本秀二、Fredrik Noborn、Jan Willem Bek、Lien Alluyn、Charlotte Gistelinck、Delfien Syx、Phil L. Salmon、Paul J. Coucke、Goran Larson、山田修平、Andy Willaert、Fransiska Malfait
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] グリコサミノグリカンの生合成に関わるb3galt6をノックアウトしたゼブラフィッシュにおけるグリコサミノグリカンの定量解析2021

    • Author(s)
      Sarah Delbaere、Adelbert De Clercq、水本秀二、Fredrik Noborn、Jan Willem Bek、Lien Alluyn、Charlotte Gistelinck、Delfien Syx、Phil L. Salmon、Paul J. Coucke、Goran Larson、山田修平、Andy Willaert、Fransiska Malfait
    • Organizer
      第85回日本生化学会中部支部例会・シンポジウム
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] ナノ液体クロマトグラフィータンデム質量分析法を用いた細胞培養液中のI型コラーゲンa鎖(COL1A1)の定量2021

    • Author(s)
      Gong Ao、山田和夫、Jing Li、竹下治男、松本健一
    • Organizer
      第53回日本結合組織学会学術大会
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] コンドロイチン/デルマタン/ヘパラン硫酸の結合領域四糖の生合成に関わるb3galt6のゼブラフィッシュ変異体におけるグリコサミノグリカンの定量2021

    • Author(s)
      水本秀二、Sarah Delbaere、Adelbert De Clercq、Fredrik Noborn、Jan Willem Bek、Lien Alluyn、Charlotte Gistelinck、Delfien Syx、Phil L. Salmon、Paul J. Coucke、Goran Larson、山田修平、Andy Willaert、Fransiska Malfait
    • Organizer
      第40回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] 前脳領域の興奮性神経特異的Extl3欠損マウスの認知機能解析2021

    • Author(s)
      小林素子、石崎愛弓、髙羽里佳、衣斐大祐、水本秀二、平松正行、菅原明、山田修平
    • Organizer
      第67回日本薬学会東海支部総会・大会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] グリコサミノグリカンの結合領域四糖(GlcA-Gal-Gal-Xyl)の生合成に関わるb3galt6を欠損したゼブラフィッシュにおけるグリコサミノグリカンの定量解析2021

    • Author(s)
      Sarah Delbaere、Adelbert De Clercq、水本秀二、Fredrik Noborn、Jan Willem Bek、Lien Alluyn、Charlotte Gistelinck、Delfien Syx、Phil L. Salmon、Paul J. Coucke、Goran Larson、山田修平、Andy Willaert、Fransiska Malfait
    • Organizer
      第53回日本結合組織学術大会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] 1歳齢の疾患モデルマウス(Chst14-/-)を用いた筋拘縮型エーラス・ダンロス症候群(mcEDS)の骨病変の解析2021

    • Author(s)
      高橋 有希、吉沢 隆浩、水本 秀二、山田 修平、古庄 知己
    • Organizer
      日本人類遺伝学会第66回大会
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] グリコサミノグリカンの生合成に関わるキシロース転移酵素の活性低下が引き起こす遺伝性骨系統疾患2021

    • Author(s)
      花立妃子、伊藤有美、山田修平、水本秀二
    • Organizer
      第53回日本結合組織学術大会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] T細胞特異的Extl3欠損マウスの作製とその解析2021

    • Author(s)
      大橋礼、大橋里帆、水本秀二、山下匡、菅原明、山田修平
    • Organizer
      第67回日本薬学会東海支部総会・大会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] 前脳領域の興奮性神経特異的Extl3欠損マウスの作製とその行動観察2021

    • Author(s)
      石崎愛弓、小林素子、髙羽里佳、衣斐大祐、水本秀二、平松正行、菅原明、山田修平
    • Organizer
      第67回日本薬学会東海支部総会・大会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] グリコサミノグリカンの結合領域四糖の生合成に関わるb3galt6をノックアウトしたゼブラフィッシュにおける骨・皮膚・筋肉の解析2021

    • Author(s)
      Sarah Delbaere、Adelbert De Clercq、水本秀二、Fredrik Noborn、Jan Willem Bek、Lien Alluyn、Charlotte Gistelinck、Delfien Syx、Phil L. Salmon、Paul J. Coucke、Goran Larson、山田修平、Andy Willaert、Fransiska Malfait
    • Organizer
      第44回日本分子生物学会大会
    • Data Source
      KAKENHI-PROJECT-21K06552
  • [Presentation] Measurement of collagen species in LX-2 cell culture medium by nano-LC/MS/MS2021

    • Author(s)
      Ao Gong、Kazuo Yamada、Haruo Takeshita、Ken-ichi Matsumoto
    • Organizer
      第2回日本エーラス・ダンロス症候群研究会
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] 疾患モデルマウスを用いた筋拘縮型エーラス・ダンロス症候群(mcEDS)の骨病変解析2021

    • Author(s)
      高橋有希、吉沢隆浩、水本秀二、山田修平、古庄知己
    • Organizer
      第2回日本エーラス・ダンロス研究会
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] Measurement of collagen species in culture medium by nano-LC/MS/MS2021

    • Author(s)
      山田和夫、Gong Ao、竹下治男、松本健一
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] Cre/LoxPシステムを利用したT細胞特異的Extl3欠損マウスの作製とその解析2021

    • Author(s)
      大橋里帆、水本秀二、山下匡、菅原明、山田修平
    • Organizer
      糖鎖科学中部拠点 第16回若手の力 フォーラム
    • Data Source
      KAKENHI-PROJECT-18K06670
  • [Presentation] 筋拘縮型エーラス・ダンロス症候群(mcEDS)の皮膚症状の疾患モデルマウスの開発2020

    • Author(s)
      吉沢隆浩、高橋有希、岳鳳鳴、水本秀二、山田修平、古庄知己
    • Organizer
      第1回日本エーラス・ダンロス研究会
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] 筋拘縮型エーラス・ダンロス症候群(mcEDS)の疾患モデルマウス(Chst14-/-)を用いた骨の表現型解析2020

    • Author(s)
      高橋有希、吉沢隆浩、水本秀二、山田修平、古庄知己
    • Organizer
      第1回日本エーラス・ダンロス研究
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] Congenital disorders caused by defects in biosynthesis of glycosaminoglycans2020

    • Author(s)
      Shuhei Yamada
    • Organizer
      Pan Pacific Connective Tissue Societies Symposium 2020
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06670
  • [Presentation] コンドロイチン硫酸修飾デコリンを用いた筋拘縮型エーラス・ダンロス症候群の診断法の開発2020

    • Author(s)
      山田和夫、Gong Ao、古庄知己、水本秀二、山田修平、竹下治男、松本健一
    • Organizer
      第1回日本エーラス・ダンロス研究
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] 免疫細胞(T細胞)特異的EXTL3欠損マウスの解析2020

    • Author(s)
      樋口直美、三宅晃代、水本秀二、山下匡、菅原明、山田修平
    • Organizer
      第52回日本結合組織学術大会
    • Data Source
      KAKENHI-PROJECT-18K06670
  • [Presentation] CRISPR/Cas9を用いて作成した筋拘縮型エーラス・ダンロス症候群モデルマウスの表現型2020

    • Author(s)
      笠原優子、積田奈々、水本秀二、井上(上野)由紀子、井上高良、髙橋(中村)有希、吉沢隆浩、髙橋有希、宮田真路、山田修平、武田伸一、渡邉淳、野村義宏、古庄知己、岡田尚巳
    • Organizer
      第1回日本エーラス・ダンロス研究
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] コンドロイチン修飾デコリンを用いた筋拘縮型エーラス・ダンロス症候群の診断法の開発2020

    • Author(s)
      山田和夫、Ao Gong、古庄知己、水本秀二、山田修平、竹下治男、松本健一
    • Organizer
      第52回日本結合組織学術大会
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] 筋拘縮型エーラス・ダンロス症候群(mcEDS)の疾患モデルマウス (Chst14-/-) を用いた骨の表現型解析2020

    • Author(s)
      高橋有希、吉沢隆浩、水本秀二、山田修平、古庄知己
    • Organizer
      第52回日本結合組織学術大会
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] 疾患モデルマウス(Chst14-/-)を用いた筋拘縮型エーラス・ダンロス症候群(mcEDS)の骨病変の解析2020

    • Author(s)
      高橋有希、吉沢隆浩、水本秀二、山田修平、古庄知己
    • Organizer
      日本人類遺伝学会第65回大会
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] 筋拘縮型エーラスダンロス症候群の疾患モデル動物としてのChst14遺伝子欠損マウスの解析2020

    • Author(s)
      吉沢隆浩、嶋田新、高橋有希、水本秀二、山田修平、山中仁木、古庄知己、松本清司
    • Organizer
      第67回日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] 脊椎骨端骨幹端異形成症患者のリンパ芽球様細胞株の産生するヘパラン硫酸の解析2019

    • Author(s)
      佐藤亨、水本秀二、大橋博文、逆井悦子、Nursel H Elcioglu、 三宅紀子 、松本直通、池川 志郎、山田 修平
    • Organizer
      第38回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-18K06670
  • [Presentation] 脳のグルタミン酸作動性神経特異的 EXTL3 欠損マウスの解析2019

    • Author(s)
      山田夏実,水本秀二,衣斐大祐,菅原明,山田 修平
    • Organizer
      第38回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-18K06670
  • [Presentation] Deletion of heparan sulfate proteoglycan syndecan-4 impairs pancreatic β-cell function in mice2019

    • Author(s)
      Iwao Takahashi, Shuhei Yamada, Koji Nata
    • Organizer
      11th International Conference on Proteoglycans
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06919
  • [Presentation] Analysis of heparan sulfate produced by lymphoblastoid cell lines in patients with spondylo-epi-metaphyseal dysplasia2019

    • Author(s)
      Toru Sato, Shuji Mizumoto, Hirofumi Ohashi, Etsuko Sakasai, Nursel H Elcioglu, Noriko Miyake, Naomichi Matsumoto, Shiro Ikegawa, Shuhei Yamada
    • Organizer
      11th international Conference on Proteoglyans
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06670
  • [Presentation] Chst14遺伝子欠損マウスを用いた筋拘縮型エーラスダンロス症候群(mcEDS)の血管・皮膚症状の病態解析2019

    • Author(s)
      吉沢隆浩、嶋田新、高橋有希、水本秀二、山田修平、古庄知己
    • Organizer
      日本人類遺伝学会第64回大会
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] Skin and Vascular Abnormalities in Chst14 Gene-Deleted Mice, an Animal Model of Musculocontractual Ehlers-Danlos Syndrome2019

    • Author(s)
      Yoshizawa T, Mizumoto S, Takahashi Y, Shimada S, Sugahara K, Nakayama J, Takeda S, Nomura Y, Nitahara-Kasahara Y, Okada T, Matsumoto K, Yamada S, Kosho T
    • Organizer
      Scientific Meeting on The Rare Types of Ehlers-Danlos Syndromes
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] Clinical, biochemical, and pathological investigation of a patient with musculocontractural Ehlers-Danlos syndrome caused by a novel pathogenic variant in DSE2019

    • Author(s)
      Minatogawa M, Mizumoto S, Hirose T, Yamaguchi T, Wakui K, Watanabe T, Yamada S, Kosho T.
    • Organizer
      American Society of Human Genetics, Annual Meeting 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03616
  • [Presentation] 免疫細胞(T 細胞)特異的 EXTL3 欠損マウスの解析2019

    • Author(s)
      三宅晃代、水本秀二、山下匡、菅原明、山田修平
    • Organizer
      第38回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-18K06670
  • [Presentation] リンパ芽球様細胞株の産生するグリコサミノグリカンの解析2018

    • Author(s)
      篠田はるか、持永磨奈美、伊藤有沙、水本秀二、逆井悦子、大橋博文、山田修平
    • Organizer
      第64回日本薬学会東海支部 総会・大会、名古屋、6/30
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] Structural studies on heparan sulfate produced by the lymphoblastoid cell lines prepared from a patient with a mutation in EXTL3 and embryonic cells from Extl3-deficient mice2018

    • Author(s)
      Shuhei Yamada, Shuji Mizumoto, Hirofumi Ohashi, Etsuko Sakasai, Nursel H Elcioglu, Noriko Miyake, Naomichi Matsumoto, Daisuke Ibi, Akira Sugawara, Shiro Ikegawa
    • Organizer
      Gordon Research Conference on Proteoglycans 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06670
  • [Presentation] ナノ液体クロマトグラフィータンデム質量分析法を用いたエーラス・ダンロス症候群の診断法の開発2018

    • Author(s)
      山田和夫、渡辺淳、古庄知己、水本秀二、山田修平、竹下治男、松本健一
    • Organizer
      第50回 日本結合組織学会学術大会、福岡、6/30
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] ヘパラン硫酸の生合成を担うEXTL3の変異は免疫不全を伴う脊椎骨端骨幹端異形成症を引き起こす2018

    • Author(s)
      水本秀二, Long Guo, Nursel H Elcioglu, Zheng Wang, Bilge Noyan, Hatice M Albayrak, 松本直通, 三宅紀子, 西村玄, 山田修平, 池川志郎
    • Organizer
      糖鎖科学中部拠点 第15回若手の力 フォーラム、静岡、9/6
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] Pathophysiological investigation of musculocontractural EDS caused by mutations in CHST14 using knock-out mice2018

    • Author(s)
      Takahiro Yoshizawa, Shuji Mizumoto, Yuki Takahashi, Shin Shimada, Kazuyuki Sugahara, Jun Nakayama, Shin’ichi Takeda, Yoshihiro Nomura, Yuko Nitahara-Kasahara, Takashi Okada, Kiyoshi Matsumoto, Shuhei Yamada, Tomoki Kosho
    • Organizer
      The International Symposium on the Ehlers-Danlos Syndromes (EDS2018),Ghent, Belgium, 9/28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] Structural alteration of glycosaminoglycan side chains and spatial disorganization of collagen networks in the skin of patients with musculocontractural Ehlers-Danlos syndrome caused by CHST14/D4ST1 deficiency2018

    • Author(s)
      Tomoki Kosho, Takuya Hirose, Naoki Takahashi, Prasarn Tangkawattana, Jun Minaguchi, Shuji Mizumoto Shuhei Yamada; Noriko Miyake, Atsushi Hatamochi, Jun Nakayama, Tomomi Yamaguchi, Kazushige Takehana
    • Organizer
      American Society of Human Genetics (ASHG) 2018, San Diego, USA, 10/19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] コンドロイチン硫酸/デルマタン硫酸生合成酵素の先天的欠損による遺伝性疾患2018

    • Author(s)
      山田修平
    • Organizer
      第31回日本軟骨代謝学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] Structural studies on heparan sulfate produced by the lymphoblastoid cell lines prepared from a patient with a mutation in EXTL3 and embryonic cells from Extl3-deficient mice2018

    • Author(s)
      Shuhei Yamada, Shuji Mizumoto, Hirofumi Ohashi, Etsuko Sakasai, Nursel H Elcioglu, Noriko Miyake, Naomichi Matsumoto, Daisuke Ibi, Akira Sugawara, and Shiro Ikegawa
    • Organizer
      Gordon Research Conference on Proteoglycans 2018, Andover, Poster, USA, 7/8-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] 免疫異常を伴う脊椎骨端骨幹端異形成症はヘパラン硫酸の生合成を担うEXTL3の変異により引き起こされる2018

    • Author(s)
      水本秀二、Long Guo, Nursel H Elcioglu, Zheng Wang, Bilge Noyan, Hatice M Albayrak, 松本直通、三宅紀子、西村 玄、山田修平、池川志郎
    • Organizer
      第37回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-18K06670
  • [Presentation] ヘパラン硫酸生合成酵素であるEXTL3の変異は免疫異常を伴う新たなタイプの脊椎骨端骨幹端異形成症を引き起こす2018

    • Author(s)
      Long Guo, Nursel H Elcioglu, Shuji Mizumoto, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Shuhei Yamada, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura, Shiro Ikegawa
    • Organizer
      日本生化学会中部支部第82回例会・シンポジウム
    • Data Source
      KAKENHI-PROJECT-18K06670
  • [Presentation] ヘパラン硫酸生合成酵素であるEXTL3の変異は免疫異常を伴う新たなタイプの脊椎骨端骨幹端異形成症を引き起こす2018

    • Author(s)
      Long Guo, Nursel H Elcioglu, Shuji Mizumoto, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Shuhei Yamada, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura1, Shiro Ikegawa
    • Organizer
      日本生化学会中部支部第82回例会・シンポジウム、岐阜、5/19
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] McEDS-CHST14患者におけるデコリン糖鎖変異のI型コラーゲン細線維形成に及ぼす影響2018

    • Author(s)
      橋本綾菜、野村義宏、広瀬拓哉、竹花一成、美名口順、水本秀二、山田修平、古庄知己、笠原優子、岡田尚巳
    • Organizer
      第50回 日本結合組織学会学術大会、福岡、6/29
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] The mammalian chondroitinase, hyaluronidase 4, is produced by human mast cells: its role in modulating the structure of chondroitin sulfate and regulating tissue remodeling2018

    • Author(s)
      Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, James Melrose, Shuhei Yamada, Bruce Caterson, and John M. Whitelock
    • Organizer
      Gordon Research Conference on Proteoglycans 2018, , Andover, Poster, USA, 7/8-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] ルイス肺がん細胞の腫瘍形成におけるRAGE欠損の影響2018

    • Author(s)
      鈴木麻未、幸村省吾、水本秀二、菅原一幸、山田修平
    • Organizer
      第64回日本薬学会東海支部 総会・大会、名古屋、6/30
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] A novel type of spondylo-epi-metaphyseal dysplasia with immuno-deficiency caused by mutation in EXTL3 encoding a glycosyltransferase responsible for biosynthesis of heparan sulfate2018

    • Author(s)
      Shuji Mizumoto, Long Guo, Nursel H Elcioglu, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura, Shuhei Yamada, and Shiro Ikegawa
    • Organizer
      The 11th International Symposium on Glycosyltransferases, Qingdao, China, 6/19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] 免疫異常を伴う脊椎骨端骨幹端異形成症はヘパラン硫酸の生合成を担うEXTL3の変異により引き起こされる2018

    • Author(s)
      水本秀二, Long Guo, Nursel H Elcioglu, Zheng Wang, Bilge Noyan, Hatice M Albayrak,松本直通, 三宅紀子, 西村玄, 山田修平, 池川志郎
    • Organizer
      第37回日本糖質学会年会、仙台、8/30
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] Musculocontractural Ehlers-Danlos syndrome caused by a CHST14 deficiency results in defect in urinary dermatan sulfate2018

    • Author(s)
      Shuji Mizumoto, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Tomomi Yamaguchi, Nobuhiko Okamoto, Noriko Miyake, Kazuyuki Sugahara, Shuhei Yamada
    • Organizer
      The International Symposium on the Ehlers-Danlos Syndromes (EDS2018),Ghent, Belgium, 9/27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] リンパ芽球様細胞株の産生するグリコサミノグリカンの解析2018

    • Author(s)
      篠田はるか、持永磨奈美、伊藤有沙、水本秀二、逆井悦子、大橋博文、山田修平
    • Organizer
      第64回日本薬学会東海支部 総会・大会
    • Data Source
      KAKENHI-PROJECT-18K06670
  • [Presentation] The mammalian chondroitinase, hyaluronidase 4, is produced by human mast cells and generates chondroitin sulfate cleavage neo-epitopes2018

    • Author(s)
      Brooke Farrugia, Megan Lord, Shuji Mizumoto, Shuhei Yamada, Bruce Caterson, John Whitelock
    • Organizer
      The AWTRS/MEPSA/ASDR Cutaneous Biology Meeting 2018, Brisbane, Australia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] Human mast cells produce the mammalian chondroitinase, hyaluronidase 4, and generate unique chondroitin sulphate structures2018

    • Author(s)
      Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, Shuhei Yamada, Bruce Caterson, and John M. Whitelock
    • Organizer
      Matrix Biology Society of Australia and New Zealand, Annual Meeting 2018, Auckland, New Zealand, 12/6
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] 発生段階の異なるマウス脳におけるグリコサミノグリカン分解酵素の発現解析2017

    • Author(s)
      禰津瑠里子、三輪一貴、水本秀二、山田修平
    • Organizer
      第36回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] ヒアルロニダーゼ1および4の基質認識に関与するアミノ酸残基の解析2017

    • Author(s)
      白水仁子、小林智恵里、稲葉史恵、安部優貴子、水本秀二、山田修平
    • Organizer
      第36回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] Ehlers-Danlos syndrome caused by mutations in CHST14/D4ST1 results in defect of urinary dermatan sulfate2017

    • Author(s)
      Shuji Mizumoto, ◯Shuhei Yamada, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Tomomi Yamaguchi, Nobuhiko Okamoto, Noriko Miyake, and Kazuyuki Sugahara
    • Organizer
      7 Lakes Proteoglycans Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] マウス脳の各発達過程におけるヒアルロン酸代謝関連酵素の発現の定量的解析2017

    • Author(s)
      山田修平、三輪一貴、水本秀二
    • Organizer
      平成28年度 新学術領域「神経糖鎖生物学」最終シンポジウム
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] The mammalian chondroitinase, hyaluronidase 4, is produced by human mast cells and generates CS cleavage neo-epitopes2017

    • Author(s)
      Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, Shuhei Yamada, Bruce Caterson, John M. Whitelock
    • Organizer
      7 Lakes Proteoglycan Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] ヒアルロニダーゼ1および4の基質認識に関与するアミノ酸残基の解析2017

    • Author(s)
      小林智恵里、白水仁子、稲葉史恵、安部優貴子、水本秀二、山田修平
    • Organizer
      第63回日本薬学会東海支部総会・大会
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] 中枢神経系におけるコンドロイチン硫酸/ヒアルロン酸の分解機構に関する研究2017

    • Author(s)
      永井冴、藤井貴夢、水本秀二、山田修平
    • Organizer
      平成28年度 新学術領域「神経糖鎖生物学」最終シンポジウム
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] Development of diagnostic method of Ehlers-Danlos syndrome using nano-LC/MS/MS2017

    • Author(s)
      ◯山田和夫、渡辺淳、古庄知己、水本秀二、山田修平、竹下治男、松本健一
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)、第40回日本分子生物学会年会、第90回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] コンドロイチン硫酸およびヘパリンはヒストンにより誘発された致死性血栓症を軽減する2017

    • Author(s)
      ○長野文彦、水野智博、水本秀二、高橋和男、坪井直毅、丸山彰一、山田修平、永松正
    • Organizer
      第63 回日本薬学会東海支部総会・大会
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] 発達段階の脳におけるコンドロイチン硫酸/ヒアルロン酸分解酵素の発現解析2017

    • Author(s)
      山田修平、三輪一貴、水本秀二
    • Organizer
      第49回日本結合組織学会学術大会
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] ルイス肺がん細胞による腫瘍形成におけるRAGE の役割に関する研究2017

    • Author(s)
      ○幸村省吾、鈴木麻未、水本秀二、菅原一幸、山田修平
    • Organizer
      第63 回日本薬学会東海支部総会・大会
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] 脊髄損傷モデルマウスへのヒアルロニダーゼの投与2017

    • Author(s)
      直井友弥、柴本秀太、水本秀二、勝又優子、森岡 幸、武内恒成、山田修平
    • Organizer
      第63回日本薬学会東海支部総会・大会
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] コンドロイチン硫酸は細胞外ヒストンによる血管内皮障害を介した臓器障害を抑制する2017

    • Author(s)
      ○長野文彦、水野智博、水本秀二、吉岡憲吾、高橋和男、坪井直毅、丸山彰一、山田修平、永松正
    • Organizer
      日本医療薬学会 第1回フレッシャーズカンファレンス
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] The mammalian chondroitinase, hyaluronidase 4, is produced by human mast cells and generates CS cleavage neo-epitopes2017

    • Author(s)
      〇Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, Shuhei Yamada, Bruce Caterson, and John M. Whitelock
    • Organizer
      7 Lakes Proteoglycans Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] デルマタン硫酸エピメラーゼ欠損によるmusculocontractural Ehlers-Danlos Syndromeの既報告3例と新規3例における臨床像の検討2017

    • Author(s)
      〇運﨑愛、Charlotte Kvist Lautrup、Keng Wee Teik、水本秀二、Heng Hock Sin、Irene Kibaek Nielsen、Sara Markholt、山田修平、松本直通、三宅紀子、古庄知己
    • Organizer
      日本人類遺伝学会第62回大会
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] コンドロイチン硫酸を特異的に加水分解するヒアルロニダーゼ4の細胞内局在の解析2017

    • Author(s)
      牧野冴紀、水本秀二、山田修平
    • Organizer
      第36回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] Integrated neuroglycobiology for proteoglycans and chondroitin sulfate-binding proteins2017

    • Author(s)
      ◯Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, Kosei Takeuchi, Yoshiaki Nakayama, Akira Kurosaka, Keiichiro Matsushima, Nobuyuki Miyamoto, Wataru Takada, Hirofumi Kodera, Naomichi Matsumoto, Hirotomo Saitsu, Gunnar Dick, James W. Fawcett, Jessica C. F. Kwok, and Kazuyuki Sugahara
    • Organizer
      平成28年度 新学術領域「神経糖鎖生物学」最終シンポジウム
    • Place of Presentation
      JPタワー名古屋(名古屋)
    • Year and Date
      2017-03-03
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] デルマタン4-O-硫酸基転移酵素-1の欠損によるエーラス・ダンロス症候群患者由来の尿中デルマタン硫酸の定量解析2016

    • Author(s)
      ◯水本秀二、古庄知己、籏持淳、本田智子、山田修平、菅原一幸
    • Organizer
      日本薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2016
    • Place of Presentation
      長良川国際会議場・岐阜都ホテル(岐阜)
    • Year and Date
      2016-10-30
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] マウス脳におけるコンドロイチン硫酸とヒアルロン酸の分解活性の検出2016

    • Author(s)
      石川輝、水本秀二、山田修平
    • Organizer
      第62回日本薬学会東海支部総会 大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] コンドロイチン硫酸に特異的な加水分解酵素であるHYAL4の酵母(Pichia pastoris)での発現および精製2016

    • Author(s)
      柴本秀太、杉田真千子、水本秀二、菅原一幸、山田修平
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-29
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] コンドロイチン硫酸を特異的に加水分解するヒアルロニダーゼ4の細胞内局在の解析2016

    • Author(s)
      三輪茜音、水本秀二、山田修平
    • Organizer
      第62回日本薬学会東海支部総会 大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] Quantification of dermatan sulfate from urine in Ehlers-Danlos syndrome caused by carbohydrate sulfotransferase 14 (CHST14)/dermatan 4-O-sulfotransferase-1 (D4ST1) deficiency2016

    • Author(s)
      ◯Shuji Mizumoto, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Shuhei Yamada, and Kazuyuki Sugahara
    • Organizer
      XXVIII International Carbohydrate (ICS2016)
    • Place of Presentation
      Marriott Hotel (New Orleans, USA)
    • Year and Date
      2016-07-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] ヒアルロニダーゼ1および4におけるコンドロイチン硫酸およびヒアルロン酸の認識に関わるアミノ酸残基の解析2016

    • Author(s)
      山田修平、安倍優貴子、山極健太郎、水本秀二
    • Organizer
      第48回日本結合組織学会学術大会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] デルマタン硫酸の生合成不全によるエーラス・ダンロス症候群の糖鎖生物学的研究2016

    • Author(s)
      水本秀二, 古庄知己, 本田智子,中島正宏, Thomas Muller, 三宅紀子, 籏持淳, 松本直通, Andreas R Janecke, 池川志郎, 菅原一幸, ○山田修平
    • Organizer
      第35回日本糖質学会年会
    • Place of Presentation
      高知市文化プラザ(高知)
    • Year and Date
      2016-09-03
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] 多発性骨折と骨粗鬆症はグリコサミノグリカンの生合成に関わる糖転移酵素の変異によって引き起こされる2016

    • Author(s)
      ◯水本秀二, Florian Job, Laurie Smith, Natario Couser, Ashley Brazil, Howard Saul, Melanie Patterson, Margaret I. Gibson, Sarah Soden, Neil Miller, Isabelle Thiffault, Carol Saunders, 山田修平, Katrin Hoffman, 菅原一幸, Emily Farrow
    • Organizer
      糖鎖科学中部拠点第13回若手の力フォーラム
    • Place of Presentation
      岐阜大学(岐阜)
    • Year and Date
      2016-11-26
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] エーラス・ダンロス症候群患者由来の尿中デルマタン硫酸の定量2016

    • Author(s)
      ◯水本秀二, 古庄知己, 籏持淳, 本田智子, 山田修平, 菅原一幸
    • Organizer
      第80回日本生化学会中部支部例会・シンポジウム
    • Place of Presentation
      三重大学講堂(津)
    • Year and Date
      2016-05-21
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] グリコサミノグリカンの生合成に関わる糖転移酵素の変異による多発性骨折と骨粗鬆症2016

    • Author(s)
      ◯水本秀二, Florian Job, Laurie Smith, Natario Couser, Ashley Brazil, Howard Saul, Melanie Patterson, Margaret I. Gibson, Sarah Soden, Neil Miller, Isabelle Thiffault, Carol Saunders, 山田修平, Katrin Hoffman, 菅原一幸, Emily Farrow
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター・東北大学川内北キャンパス (仙台)
    • Year and Date
      2016-09-27
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] 脳・神経系におけるコンドロイチン硫酸/ヒアルロン酸分解機構に関する研究2016

    • Author(s)
      山田修平、永井冴、三輪一貴、水本秀二
    • Organizer
      第48回日本結合組織学会学術大会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] Multiple fractures and severe osteoporosis caused by mutations in a glycosyltransferase responsible for biosynthesis of glycosaminoglycans2016

    • Author(s)
      ◯Shuji Mizumoto, Florian Job, Laurie Smith, Natario Couser, Ashley Brazil, Howard Saul, Melanie Patterson, Margaret I. Gibson, Sarah Soden, Neil Miller, Isabelle Thiffault, Carol Saunders, Shuhei Yamada, Katrin Hoffman, Kazuyuki Sugahara, Emily Farrow
    • Organizer
      The 10th International Symposium on Glycosyltransferases (GlycoT2016)
    • Place of Presentation
      The Hospital for Sick Children (Tronto, Canada)
    • Year and Date
      2016-06-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08251
  • [Presentation] Studies on the mechanism of degradation of chondroitin sulfate/hyaluronan in central nervous system2016

    • Author(s)
      Shuhei Yamada, Sae Nagai, Shuji Mizumoto
    • Organizer
      XXVIII International Carbohydrate Symposium
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] Detection of the degradation activities of chondroitin sulfate and hyaluronan in mouse brain as well as cultured cell lines2016

    • Author(s)
      ◯Shuji Mizumoto, Tomomasa Yamanaka, Sae Nagai, and Shuhei Yamada
    • Organizer
      The 3rd International Symposium on Glyco-Neuroscience
    • Place of Presentation
      淡路夢舞台国際会議場(淡路)
    • Year and Date
      2016-01-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25860037
  • [Presentation] Quantitative analysis of the expression of hyaluronan-chondroitin sulfate-degrading enzymes in the mouse brain during development.2016

    • Author(s)
      Kazutaka Miwa, Shuji Mizumoto, Shuhei Yamada
    • Organizer
      XXVIII International Carbohydrate Symposium
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] Investigation of the amino acid residues in hyaluronidases-1 and -4 responsible for their substrate recognition2016

    • Author(s)
      Yukiko Abe, Kentaro Yamagiwa, Shuji Mizumoto, Shuhei Yamada
    • Organizer
      XXVIII International Carbohydrate Symposium
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] コンドロイチン硫酸に特異的な加水分解酵素であるHYAL4の酵母 (Pichia pastoris) での発現および精製2016

    • Author(s)
      柴本秀太、杉田真千子、水本秀二、菅原一幸、山田修平
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-29
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] 発生段階の異なるマウス脳におけるヒアルロニダーゼファミリーメンバーの発現解析2015

    • Author(s)
      三谷真夕、水本秀二、山田修平
    • Organizer
      第34回日本糖質学会年会
    • Place of Presentation
      東京
    • Year and Date
      2015-08-02
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] Investigation of the Amino Acid Residue Responsible for Diferrent Substrate Specificity of Hyaluronidases-1 and -42015

    • Author(s)
      Kentaro Yamagiwa, Haruna Iwatsuki, Yukiko Abe, Shuji Mizumoto, and Shuhei Yamada
    • Organizer
      9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2015-08-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] ヒアルロニダーゼ1および4におけるコンドロイチン硫酸およびヒアルロン酸の認識に関わるアミノ酸残基の解析2015

    • Author(s)
      安倍優貴子、山極健太郎、岩月遥奈、水本秀二、山田修平
    • Organizer
      第38回日本分子生物学会年会 第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-02
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] ヒアルロニダーゼ1と4の基質認識の違いに関与するアミノ酸残基の解析2015

    • Author(s)
      山極健太郎、岩月遥奈、安倍優貴子、水本秀二、山田修平
    • Organizer
      第34回日本糖質学会年会
    • Place of Presentation
      東京
    • Year and Date
      2015-08-02
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] Quantitative Analysis of the Expression of Hyaluronidases in the Mouse Brain during Development2015

    • Author(s)
      Mayu Mitani, Shuji Mizumoto, Shuhei Yamada
    • Organizer
      9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2015-08-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] 発生段階の異なるマウス脳におけるヒアルロニダーゼファミリーメンバーの発現解析2015

    • Author(s)
      三谷真夕、水本秀二、山田修平
    • Organizer
      第34回日本糖質学会年会
    • Place of Presentation
      東京
    • Year and Date
      2015-08-02
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] Cellular Localization of Chondroitin Sulfate Hydrolase, Hyaluronidase-42015

    • Author(s)
      Yumiko Nomura, Shuji Mizumoto, and Shuhei Yamada
    • Organizer
      9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2015-08-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] ヒアルロニダーゼ1および4におけるコンドロイチン硫酸およびヒアルロン酸の認識に関わるアミノ酸残基の解析2015

    • Author(s)
      安倍優貴子、山極健太郎、岩月遥奈、水本秀二、山田修平
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-02
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] ヒトの癌細胞株や癌組織におけるヒアルロニダーゼ4の発現解析2015

    • Author(s)
      西島大樹、水本秀二、山田修平
    • Organizer
      第61回日本薬学会東海支部大会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-07-04
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] Investigation of the Amino Acid Residue Responsible for Diferrent Substrate Specificity of Hyaluronidases-1 and -42015

    • Author(s)
      Kentaro Yamagiwa, Haruna Iwatsuki, Yukiko Abe, Shuji Mizumoto, and Shuhei Yamada
    • Organizer
      9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2015-08-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] ヒアルロニダーゼ1と4の基質認識の違いに関与するアミノ酸残基の解析2015

    • Author(s)
      山極健太郎、岩月遥奈、安倍優貴子、水本秀二、山田修平
    • Organizer
      第34回日本糖質学会年会
    • Place of Presentation
      東京
    • Year and Date
      2015-08-02
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] 酵母(Pichia pastoris)を用いたヒアルロニダーゼ4の発現及び精製2015

    • Author(s)
      杉田真千子、柴本秀太、水本秀二、菅原一幸、山田修平
    • Organizer
      第34回日本糖質学会年会
    • Place of Presentation
      東京
    • Year and Date
      2015-08-02
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] サケ鼻軟骨由来のコンドロイチン硫酸プロテオグリカンの構造解析2015

    • Author(s)
      横井友哉、松崎南美、桝谷晃明、坪井誠、菅原一幸、山田修平
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      デザインクリエイティブセンター神戸(神戸)
    • Year and Date
      2015-03-28
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] Quantitative Analysis of the Expression of Hyaluronidases in the Mouse Brain during Development2015

    • Author(s)
      Mayu Mitani, Shuji Mizumoto, Shuhei Yamada
    • Organizer
      9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2015-08-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] 脳・神経系に由来する培養細胞株を用いたコンドロイチン硫酸/ヒアルロン酸分解活性の検出2015

    • Author(s)
      永井冴、山中智正、水本秀二、山田修平
    • Organizer
      第38回日本分子生物学会年会 第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-02
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] 酵母(Pichia pastoris)を用いたヒアルロニダーゼ4の発現及び精製2015

    • Author(s)
      杉田真千子、柴本秀太、水本秀二、菅原一幸、山田修平
    • Organizer
      第34回日本糖質学会年会
    • Place of Presentation
      東京
    • Year and Date
      2015-08-02
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] Cellular localization of chondroitin sulfate hydrolase, hyaluronidase-42015

    • Author(s)
      Yumiko Nomura, Shuji Mizumoto, and Shuhei Yamada
    • Organizer
      9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2015-08-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07951
  • [Presentation] サケ鼻軟骨由来のコンドロイチン硫酸プロテオグリカンの構造解析2015

    • Author(s)
      横井友哉、松崎南美、桝谷晃明、坪井誠、菅原一幸、山田修平
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      デザインクリエイティブセンター神戸(神戸)
    • Year and Date
      2015-03-28
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] Expression Analysis of Hyaluronidases in the Mouse Brain during Development2014

    • Author(s)
      Yuka Oiwa, Shuji Mizumoto, Ryoji Kojima, Tadashi Nagamatsu, Shuhei Yamada
    • Organizer
      Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research “Glycans in Neuroscience”
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2014-11-16
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] 妊娠マウスにおける膵臓ランゲルハンス島のヘパラン硫酸の構造変化2014

    • Author(s)
      松崎南美、西田祐美、高橋巌、那谷耕司、山田修平
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] グリコサミノグリカンの代謝2014

    • Author(s)
      山田 修平
    • Organizer
      第8回東北糖鎖研究会
    • Place of Presentation
      岩手医科大学(矢巾町、岩手)
    • Year and Date
      2014-10-10
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] 発生段階の異なるマウス脳におけるヒアルロニダーゼファミリーメンバーの発現解析2014

    • Author(s)
      大岩友香、水本秀二、小島良二、永松正、山田修平
    • Organizer
      第60回日本薬学会東海支部総会
    • Place of Presentation
      鈴鹿医療大学(鈴鹿)
    • Year and Date
      2014-07-05
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] グリコサミノグリカンの代謝2014

    • Author(s)
      山田 修平
    • Organizer
      第8回東北糖鎖研究会
    • Place of Presentation
      岩手医科大学(矢巾町、岩手)
    • Year and Date
      2014-10-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] コンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の細胞内局在の解析2014

    • Author(s)
      森本千夏、野村優美子、水本秀二、山田修平
    • Organizer
      第60回日本薬学会東海支部総会
    • Place of Presentation
      鈴鹿医療大学(鈴鹿)
    • Year and Date
      2014-07-05
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] Expression Analysis of Hyaluronidases in the Mouse Brain during Development2014

    • Author(s)
      Yuka Oiwa, Shuji Mizumoto, Ryoji Kojima, Tadashi Nagamatsu, Shuhei Yamada
    • Organizer
      Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research “Integrating Glycoscience from Biology and Chemistry to Medicine”
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2014-11-18
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] Integrated neuroglycobiology for proteoglycans and chondroitin sulfate-binding proteins2014

    • Author(s)
      Kazuyuki Sugahara, Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, Kosei Takeuchi, Yoshiaki Nakayama, Akira Kurosaka, Keiichiro Matsushima, Nobuyuki Miyamoto, Wataru Takada, Hirofumi Kodera, Naomichi Matsumoto, Hirotomo Saitsu, Gunnar Dick, James W. Fawcett, Jessica C. F. Kwok
    • Organizer
      International Symposium on Glyco-Neuroscience
    • Place of Presentation
      Awaji
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] 発生段階の異なるマウス脳におけるヒアルロニダーゼファミリーメンバーの発現解析2014

    • Author(s)
      大岩友香、水本秀二、小島良二、永松正、山田修平
    • Organizer
      第60回日本薬学会東海支部総会
    • Place of Presentation
      鈴鹿医療大学(鈴鹿)
    • Year and Date
      2014-07-05
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] ヒトヒアルロニダーゼの基質認識に必要なアミノ酸残基の解析2014

    • Author(s)
      岩月遥奈、水本秀二、金岩知之、菅原一幸、山田修平
    • Organizer
      第60回日本薬学会東海支部総会
    • Place of Presentation
      鈴鹿医療大学(鈴鹿)
    • Year and Date
      2014-07-05
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] コンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の細胞内局在の解析2014

    • Author(s)
      森本千夏、野村優美子、水本秀二、山田修平
    • Organizer
      第60回日本薬学会東海支部総会
    • Place of Presentation
      鈴鹿医療大学(鈴鹿)
    • Year and Date
      2014-07-05
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] コンドロイチン硫酸代謝におけるヒアルロニダーゼの役割2014

    • Author(s)
      山田修平、本田智子、金岩知之、水本秀二、菅原一幸
    • Organizer
      第46回日本結合組織学会学術大会第61回マトリックス研究会大会合同学術集会
    • Place of Presentation
      ウインク愛知(名古屋)
    • Year and Date
      2014-06-06
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] Role of Hyaluronidases in the Catabolism of Chondroitin Sulfate2014

    • Author(s)
      Shuhei Yamada
    • Organizer
      10th International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules
    • Place of Presentation
      Kolkata, India
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] ヒトヒアルロニダーゼの基質認識に必要なアミノ酸残基の解析2014

    • Author(s)
      岩月遥奈、水本秀二、金岩知之、菅原一幸、山田修平
    • Organizer
      第60回日本薬学会東海支部総会
    • Place of Presentation
      鈴鹿医療大学(鈴鹿)
    • Year and Date
      2014-07-05
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] コンドロイチン硫酸代謝におけるヒアルロニダーゼの役割2014

    • Author(s)
      山田修平、本田智子、金岩知之、水本秀二、菅原一幸
    • Organizer
      第46回日本結合組織学会学術大会第61回マトリックス研究会大会合同学術集会
    • Place of Presentation
      名古屋大学(名古屋)
    • Year and Date
      2014-06-06
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • [Presentation] Expression Analysis of Hyaluronidases in the Mouse Brain during Development2014

    • Author(s)
      Yuka Oiwa, Shuji Mizumoto, Ryoji Kojima, Tadashi Nagamatsu, Shuhei Yamada
    • Organizer
      oint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research “Integrating Glycoscience from Biology and Chemistry to Medicine”
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2014-11-18
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] Mass preparation of oligosaccharides with intestinal absorption capacity by hydrolysis of chondroitin sulfate polysaccharides with subcritical water microreaction system2013

    • Author(s)
      Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, and Nobuyuki Miyamoto
    • Organizer
      The 13th International Conference on Functional and Medical Foods with Bioactive Compounds : Science and Practical Applications/The First International Symposium of Academic Society for Functional Foods and Bioactive Compounds
    • Place of Presentation
      The Kyoto Prefectural University (Kyoto)
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] Mass Preparation of Oligosaccharides with Intestinal Absorption Capacity by Hydrolysis of Chondroitin Sulfate Polysaccharides with Subcritical Water Microreaction System2013

    • Author(s)
      Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, and Nobuyuki Miyamoto
    • Organizer
      13th International Conference of FFC and 1st International Symposium of Academic Society for Functional Foods and Bioactive Compounds
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] マイクロ化学プロセスによる新規糖鎖食品の開発2013

    • Author(s)
      松嶋景一郎、浦晴雄、宮本宣之、菅原一幸、山田修平、水本秀二
    • Organizer
      北海道立総合研究機構 技術移転フォーラム2013
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences involved in brain development2013

    • Author(s)
      Kazuyuki Sugahara, Shuji Mizumoto, Kittiwan Kalayanamitra, Shuhei Yamada, and Prachya Kongtawelert
    • Organizer
      8th International Conference on Proteoglycans
    • Place of Presentation
      Frankfurt, Germany
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] マイクロ化学プロセスを利用したコンドロイチン硫酸オリゴ糖の大量調製方法の確立2013

    • Author(s)
      山田修平、松嶋景一郎、浦晴雄、宮本宣之、菅原一幸
    • Organizer
      第32回日本糖質学会年会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] 第59回日本薬学会東海支部総会2013

    • Author(s)
      山田修平、松嶋景一郎、浦晴雄、宮本宣之、菅原一幸
    • Organizer
      第59回日本薬学会東海支部総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] Studies on the Role of Hyaluronidases in the Catabolism of Chondroitin Sulfate2013

    • Author(s)
      Shuhei Yamada
    • Organizer
      8th International Conference on Proteoglycans
    • Place of Presentation
      Frankfurt, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] グリコサミノグリカンの生合成・代謝・機能の研究2013

    • Author(s)
      山田修平
    • Organizer
      糖鎖化学中部拠点 第11回「若手の力」フォーラム
    • Place of Presentation
      名古屋
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] ヒトとマウスにおけるコンドロイチン硫酸加水分解酵素の基質特異性の違いに関わるアミノ酸残基の同定2013

    • Author(s)
      山田修平、金岩知之、宮崎杏、古川諒、水本秀二、菅原一幸
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] ヒアルロニダーゼはコンドロイチン4-硫酸に対しヒアルロン酸と同程度の強い加水分解活性をもつ2013

    • Author(s)
      山田修平、本田智子、金岩知之、水本秀二、菅原一幸
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] コンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の酵素活性に必要なアミノ酸残基の同定2012

    • Author(s)
      山田修平、金岩知之、宮崎杏、水本秀二、菅原一幸
    • Organizer
      第58回日本薬学会東海支部 総会・大会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] コンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の酵素活性に必要なアミノ酸残基の同定2012

    • Author(s)
      金岩知之、宮崎杏、水本秀二、菅原一幸、山田修平
    • Organizer
      第49回日本生化学会北海道支部例会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] ヒアルロニダーゼの本来の基質はヒアルロン酸ではなくコンドロイチン硫酸2012

    • Author(s)
      山田修平、本田智子、金岩知之、水本秀二、菅原一幸
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] コンドロイチン硫酸に特異的な加水分解酵素に関する研究2012

    • Author(s)
      山田修平,金岩知之,宮崎杏,古川諒,水本秀二,菅原一幸
    • Organizer
      第31回日本糖質学会年会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] 「Shrimp head heparan sulfate with unique structure and function2012

    • Author(s)
      Yoshiki Hama, Chen Jiancheng, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Eunmi Kim, Takashi Kimura, Kazuyuki Sugahara, Shuhei Yamada
    • Organizer
      The IGP International Symposium 2012
    • Place of Presentation
      Sapporo
    • Year and Date
      2012-03-02
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] 哺乳類におけるコンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の基質認識に必要なアミノ酸残基の同定2012

    • Author(s)
      Shuhei Yamada
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] ヒトヒアルロニダーゼはコンドロイチン硫酸Aをヒアルロン酸と同程度の速度で加水分解する2012

    • Author(s)
      本田智子、金岩知之、水本秀二、菅原一幸、山田修平
    • Organizer
      第49回日本生化学会北海道支部例会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences involved in brain development2012

    • Author(s)
      Shuji Mizumoto, Saori Murakoshi,Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fukui, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
    • Organizer
      2012年度包括型脳科学研究推進支援ネットワーク・夏のワークショップ
    • Place of Presentation
      仙台国際センター、(ポスター発表)
    • Year and Date
      2012-07-26
    • Data Source
      KAKENHI-PROJECT-23790066
  • [Presentation] コンドロイチン硫酸特異的加水分解酵素の発現組織の解析および精巣における機能の研究2012

    • Author(s)
      古川諒、金岩知之、宮崎杏、菅原一幸、山田修平
    • Organizer
      日本薬学会北海道支部137例会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] サメヒレ軟骨コンドロイチン硫酸由来の新規な六糖配列の単離2012

    • Author(s)
      水本秀二,村越早織,Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, 福井成行, Prachya Kongtawelert, 山田修平, 菅原一幸
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場およびマリンメッセ福岡、(ポスター発表)
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-23790066
  • [Presentation] コンドロイチン硫酸特異的加水分解酵素の発現組織の解析およびその機能の研究2012

    • Author(s)
      古川諒、金岩知之 、宮崎杏、菅原一幸、山田修平
    • Organizer
      第49回日本生化学会北海道支部例会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] Shrimp head heparan sulfate with unique structure and function2012

    • Author(s)
      Yoshiki Hama, Chen Jiancheng, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Eunmi Kim, Takashi Kimura, Kazuyuki Sugahara, Shuhei Yamada
    • Organizer
      The IGP International Symposium 2012
    • Place of Presentation
      Hokkaido Univ. (Sapporo)
    • Year and Date
      2012-03-02
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] ヒトヒアルロニダーゼのコンドロイチン4硫酸に対する高い加水分解活性2012

    • Author(s)
      本田智子、金岩知之、水本秀二、菅原一幸、山田修平
    • Organizer
      第31回日本糖質学会年会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] ユニークな構造と機能をもつエビ頭部に由来するヘパラン硫酸2012

    • Author(s)
      羽磨紀城, 陳建成, Ajaya Kumar Shetty, 小林孝成, 織田浩司, 清木興介, Eunmi Kim, 木村享史, 菅原一幸, 山田修平
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E構造の発現低下による転移抑制2011

    • Author(s)
      水本秀二、渡邊基夫、山田修平、菅原一幸
    • Organizer
      日本薬学会北海道支部第136回例会
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] エビ頭部由来ヘパラン硫酸の構造と機能の研究2011

    • Author(s)
      陳建成、羽磨紀城、Ajaya Kumar Shetty、小林孝成、織田浩司、清木興介、木村享史、高橋尚徳、左一八、鈴木隆、鈴木康夫、〇山田修平、菅原一幸
    • Organizer
      日本薬学会北海道支部第136回例会
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] エビ頭部に由来するヘパラン硫酸の構造と生物活性2011

    • Author(s)
      羽磨紀城, 陳建成, Ajaya Kumar Shetty, 小林孝成, 織田浩司, 清木興介, Eunmi Kim, 木村享史, 菅原一幸, 山田修平
    • Organizer
      第30回日本糖質学会年会
    • Place of Presentation
      長岡リリックホール(長岡市)
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] Studies on novel mammalian endo-type chondroitin sulfate hydrolases2011

    • Author(s)
      T. Kaneiwa, A. Miyazaki, S. Mizumoto, K. Sugahara, S. Yamada
    • Organizer
      The 3rd FEBS-MPST Advanced Lecture Course on Matrix Pathobiology, Signaling andMolecular Targets (FEBS-MPST2011).
    • Place of Presentation
      Spetses, Greece
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] コンドロイチン硫酸E構造の発現調節によるルイス肺癌細胞の転移抑制2011

    • Author(s)
      水本秀二、渡邊基夫、山田修平、菅原一幸
    • Organizer
      日本薬学会北海道支部第136例会
    • Place of Presentation
      札幌コンベンションセンター、(口頭発表)
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-23790066
  • [Presentation] Mouse hyaluronidase-4 : Identification of a chondroitin sulfate-specific hydrolase with distinct specificity from human hyaluronidase-42011

    • Author(s)
      Shuhei Yamada
    • Organizer
      The 31st Naito Conference. Glycan Expression and Regulation [II] : Metabolites, Stress Response, Microdomains, Beyond
    • Place of Presentation
      CHATERAISE Gateaux Kingdom (Sapporo)
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] ヒトヒアルロニダーゼ4とマウスヒアルロニダーゼ4の基質特異性の比較2011

    • Author(s)
      山田修平
    • Organizer
      第30回日本糖質学会年会
    • Place of Presentation
      リリックホール・ハイブ長岡(長岡市)
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] 「Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in ?-Thrombomodulin from Human Urine」2011

    • Author(s)
      T. Hashiguchi, S. Mizumoto, Y. Nishimura, J. Tamura, S. Yamada, K. Sugahara
    • Organizer
      7th International Conference onProteoglycans
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2011-10-20
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in a-Thrombomodulin from Human Urine2011

    • Author(s)
      T. Hashiguchi, S. Mizumoto, Y. Nishimura, J. Tamura, ○S. Yamada, K. Sugahara
    • Organizer
      7th International Conference on Proteoglycans
    • Place of Presentation
      Q STATION (Australia)
    • Year and Date
      2011-10-18
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] Loss-of-function mutations of dermatan 4-O-sulfotransferase-1 cause a new type of Ehlers-Danlos syndrome2011

    • Author(s)
      Shuji Mizumoto, Noriko Miyake, Tomoki Kosho, Shuhei Yamada, Kazuyuki Sugahara, and Naomichi Matsumoto
    • Organizer
      The 9th International Symposium for Future Drug Discovery and Medical Care
    • Place of Presentation
      Hokkaido Univ、(Poster)
    • Year and Date
      2011-09-30
    • Data Source
      KAKENHI-PROJECT-23790066
  • [Presentation] エビ頭部由来へパラン硫酸の構造と機能の研究2011

    • Author(s)
      陳建成, 羽磨紀城, Ajaya Kumar Shetty, 小林孝成, 織田浩司, 清木興介, 木村享史, 高橋尚徳, 左一八, 鈴木隆, 鈴木康夫, ○山田修平, 菅原一幸
    • Organizer
      日本薬学会北海道支部第136回例会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] Analysis of the expression pattern of dermatan sulfate epimerase-2, which is involved in the bipolar disorder, in the mouse brain during postnatal development2011

    • Author(s)
      Chizuru Akatsu, Shuji Mizumoto, Tomoyuki Kaneiwa, Marco Maccarana, Anders Malmström, Shuhei Yamada, ○Kazuyuki Sugahara
    • Organizer
      The 9th International Symposium for Future Drug Discovery and Medical Care
    • Place of Presentation
      Hokkaido Univ. (Sapporo)
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-0-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in a-Thrombomodulin from Human Urine2011

    • Author(s)
      T.Hashiguchi, S.Mizumoto, Y.Nishimura, J.Tamura, 〇S.Yamada, K.Sugahara
    • Organizer
      7th International Conference on Proteoglycans
    • Place of Presentation
      QSTATION (Australia)
    • Year and Date
      2011-10-18
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] コンドロイチン硫酸/デルマタン硫酸の生合成に関わる酵素の欠損による骨・皮膚疾患2011

    • Author(s)
      水本秀二,三宅紀子,古庄知己, Mirjam H.H. van Roij, Beyhan Tuysuz,Stefan Mundlos, Stephen P. Robertson, 山田修平, 松本直通, 菅原一幸
    • Organizer
      第30回日本糖質学会年会
    • Place of Presentation
      長岡リリックホール、(口頭発表)
    • Year and Date
      2011-07-11
    • Data Source
      KAKENHI-PROJECT-23790066
  • [Presentation] コンドロイチン硫酸/デルマタン硫酸の生合成に関わる酵素の欠損による骨・皮膚疾患2011

    • Author(s)
      ○水本秀二, 三宅紀子, 古庄知己, Mirjam H.H. van Roij, Beyhan Tuysuz, Stefan Mundlos, Stephen P. Robertson, 山田修平, 松本直通, 菅原一幸
    • Organizer
      第30回日本糖質学会年会
    • Place of Presentation
      長岡リリックホール(新潟県)
    • Data Source
      KAKENHI-PROJECT-23790066
  • [Presentation] 新規のコンドロイチン硫酸に特異的な加水分解酵素の同定2011

    • Author(s)
      山田修平
    • Organizer
      第19回糖質関連酵素化学シンポジウム
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2011-09-30
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Loss-of-function mutations of dermatan 4-O-sulfotransferase-1 cause a new type of Ehlers-Danlos syndrome2011

    • Author(s)
      ◯Shuji Mizumoto, Noriko Miyake, Tomoki Kosho, Shuhei Yamada, Kazuyuki Sugahara, and Naomichi Matsumoto
    • Organizer
      The 9th International Symposium for Future Drug Discovery and Medical Care
    • Place of Presentation
      Hokkaido Univ. (Sapporo)
    • Data Source
      KAKENHI-PROJECT-23790066
  • [Presentation] エビ頭部に由来するヘパラン硫酸の構造と生物活性2011

    • Author(s)
      羽磨紀城、陳建成、Ajaya Kumar Shetty、小林孝成、織田浩司、清木興介、Eunmi Kim、木村享史、菅原一幸、山田修平
    • Organizer
      第30回日本糖質学会年会
    • Place of Presentation
      長岡リリックホール(新潟県)
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] Mouse hyaluronidase-4 : Identification of a chondroitin sulfate-specific hydrolase with distinct specificity from human hyaluronidase-42011

    • Author(s)
      S. Yamada, A. Miyazaki, T. Kaneiwa, S. Mizumoto, and K. Sugahara
    • Organizer
      The 31st Naito Conference. Glycan Expression and Regulation [II]: Metabolites, Stress Response, Microdomains, and Beyond.
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in a-Thrombomodulin from Human Urine2011

    • Author(s)
      Shuhei Yamada
    • Organizer
      7th International Conference on Proteoglycans
    • Place of Presentation
      QSTATION (Australia)
    • Year and Date
      2011-10-20
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Chondroitin sulfate-specific novel hydrolase in human2011

    • Author(s)
      山田修平
    • Organizer
      9th International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules
    • Place of Presentation
      Trivandrum, Kerala, India
    • Year and Date
      2011-01-28
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Specific interaction of the envelope glycoproteins E1 and E2 with liver heparan sulfate involved in the tissue tropismatic infection by hepatitis C virus2011

    • Author(s)
      Shuhei Yamada
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E構造の発現低下による転移抑制2011

    • Author(s)
      渡邊基夫、水本秀二、山田修平、菅原一幸
    • Organizer
      第30回日本糖質学会年会
    • Place of Presentation
      長岡リリックホール(新潟県)
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E 構造の発現低下による転移抑制2011

    • Author(s)
      水本秀二, 渡邊基夫, 山田修平, 菅原一幸
    • Organizer
      日本薬学会北海道支部第136回例会
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E 構造の発現低下による転移抑制2011

    • Author(s)
      渡邊基夫, 水本秀二, 山田修平, ○菅原一幸
    • Organizer
      第30回日本糖質学会年会
    • Place of Presentation
      長岡リリックホール(長岡市)
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] Determination of amino acid sequences in hyaluronidase-4 responsible for the substrate recognition2011

    • Author(s)
      T. Kaneiwa, A. Miyazaki, S. Mizumoto, K. Sugahara, and S. Yamada
    • Organizer
      7th International Conference on Proteoglycans
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2011-10-18
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Chondroitin sulfate-specific novel hydrolase in human.2011

    • Author(s)
      Shuhei Yamada
    • Organizer
      9th International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules
    • Place of Presentation
      Trivandrum, Kerala, India(招待講演)
    • Year and Date
      2011-01-28
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Structural characterization of heparan sulfate in the Extl3 knockout mice and the pancreatic β-cell specific Extl3 knockout mice.2010

    • Author(s)
      Shuhei Yamada
    • Organizer
      The 25^<th> International Carbohydrate Symposium (ICS2010)
    • Place of Presentation
      Chiba
    • Year and Date
      2010-08-02
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Presentation] Identification of a chondroitin sulfate-specific novel hydrolase in human2010

    • Author(s)
      T. Kaneiwa, S. Mizumoto, K. Sugahara, S. Yamada
    • Organizer
      The 25th International Carbohydrate Symposium (ICS2010)
    • Place of Presentation
      Chiba
    • Year and Date
      2010-08-05
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] The E-type structure of chondroitin sulfate on tumor cell surfaces is involved in lung and liver metastases.2010

    • Author(s)
      Kazuyuki Sugahara, Fuchuan Li, Sengottuvelan Murugan, Basappa, Taishi Hashiguchi, Shuji Mizumoto, Shuhei Yamada, Kayoko Oguri, Minoru Okayama, Kazuki N.Sugahara, Chun Man Lee, Masayuki Miyasaka, Gerdy B.ten Dam, Toin H.van Kuppevelt
    • Organizer
      Asian Communications of Glycobiology and Glycotechnology (ACGG)
    • Place of Presentation
      Taipei
    • Year and Date
      2010-10-27
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Presentation] Structural characterization of heparan sulfate in the Extl3 knockout mice and the pancreatic β-cell specific Extl3 knockout mice.2010

    • Author(s)
      Shuhei Yamada
    • Organizer
      The 25th International Carbohydrate Symposium (ICS2010)
    • Place of Presentation
      Chiba
    • Year and Date
      2010-08-02
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Involvement of the Hepatocyte Growth Factor Signaling Pathway in the Neuritogenic Activity of Chondroitin Sulfate Derived from Ray Fish Cartilage2010

    • Author(s)
      T. Hashiguchi, T. Kobayashi, D. Fongmoon, A. K. Shetty, S. Mizumoto, N. Miyamoto, T. Nakamura, S. Yamada, and K. Sugahara
    • Organizer
      The 25th International Carbohydrate Symposium (ICS2010)
    • Place of Presentation
      Chiba
    • Year and Date
      2010-08-03
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Structural characterization of heparan sulfate in the Extl3 knockout mice and the pancreatic β-cell specific Extl3 knockout mice2010

    • Author(s)
      T. Kaneiwa, S. Yamada, K. Sugahara, I. Takahashi, N. Noguchi, K. Nata, H. Okamoto, A. Sugawara
    • Organizer
      The 25th International Carbohydrate Symposium (ICS2010)
    • Place of Presentation
      Chiba
    • Year and Date
      2010-08-02
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] コンドロイチン硫酸と芯タンパク質の結合領域に対するモノクローナル抗体の開発とその反応性の解析2010

    • Author(s)
      山田修平
    • Organizer
      BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] コンドロイチン硫酸と芯タンパク質の結合領域に対するモノクローナル抗体の開発とその反応性の解析2010

    • Author(s)
      山田修平
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Presentation] Demonstration of chondroitin sulfate-specific hydrolytic activity in human hyaluronidase-42010

    • Author(s)
      T. Kaneiwa, S. Mizumoto, K. Sugahara, S. Yamada
    • Organizer
      The 8th International Conference on Hyaluronan Sciences
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Identification of a novel chondroitin sulfate hydrolase applicable to neuronal regenerative therapy2010

    • Author(s)
      Trivandrum, Kerala, IndiaT. Kaneiwa, S. Mizumoto, K. Sugahara, S. Yamada
    • Organizer
      The 8th International Symposium for Future Drug Discovery and Medical Care
    • Place of Presentation
      Sapporo
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Identification of human hyaluronidase-4 as a novel chondroitin sulfate hydrolase that preferentially cleaves the specific linkage in a highly sulfated sequence.2009

    • Author(s)
      Shuhei Yamada
    • Organizer
      6th international Conference on Proteoglycan
    • Place of Presentation
      Aix-les-Bains, France
    • Year and Date
      2009-09-15
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Identification of human hyaluronidase-4 as a novel chondroitin sulfate hydrolase that preferentially cleaves the specific linkage in a highly sulfated sequence.2009

    • Author(s)
      Shuhei Yamada
    • Organizer
      6th International Conference on Proteoglycan
    • Place of Presentation
      Aix-les-Bains, France
    • Year and Date
      2009-09-15
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Presentation] マウス癌細胞株の肺および肝臓への転移にはコンドロイチン硫酸E様構造が関与する2009

    • Author(s)
      山田修平
    • Organizer
      第29回日本糖質学会年会
    • Place of Presentation
      高山
    • Year and Date
      2009-09-09
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Presentation] Cell surface chondroitin sulfate E type structure of mouse tumor cell lines is involved in the experimental metastasis to the lung and liver.2009

    • Author(s)
      Shuhei Yamada
    • Organizer
      6th International Conference on Proteoglycan
    • Place of Presentation
      Aix-les-Bains, France
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Presentation] Extl3 KOマウス及び膵ss細胞特異的なExtl3 KOマウスのヘパラン硫酸の分析2009

    • Author(s)
      山田修平
    • Organizer
      第29回日本糖質学会年会
    • Place of Presentation
      高山
    • Year and Date
      2009-09-11
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Presentation] Identification and characterization of a novel chondroitin hydrolase in Caenorhabditis elegans2009

    • Author(s)
      Tomoyuki Kaneiwa, Shuhei Yamada, Shuji Mizumoto, Adriana M. Montano, Shohei Mitani, and Kazuyuki Sugahara
    • Organizer
      2nd Symposium on Structural Analysis of Biological Macromolecules & 7th Japan-Korea Bilateral Symposium on Biological NMR
    • Place of Presentation
      Sapporo
    • Year and Date
      2009-07-27
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Extl3 KOマウス及び膵B細胞特異的なExtl3 KOマウスのヘパラン硫酸の分析2009

    • Author(s)
      山田修平
    • Organizer
      第29回日本糖質学会年会
    • Place of Presentation
      高山
    • Year and Date
      2009-09-11
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Identification and characterization of a novel chondroitin hydrolase in Caenorhabditis elegans2009

    • Author(s)
      Tomoyuki Kaneiwa, Shuhei Yamada, Shuji Mizumoto, Adriana M. Montano, Muneyoshi Otori, Shohei Mitani, and Kazuyuki Sugahara
    • Organizer
      6th International Conference on Proteoglycan
    • Place of Presentation
      Aix-les-Bains, France
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Cell surface chondroitin sulfate E type structure of mouse tumor cell lines is involved in the experimental metastasis to the lung and liver.2009

    • Author(s)
      Kazuyuki Sugahara, Shuhei Yamada, Sengottuvelan Murugan, Fuchuan Li, Basappa, Taishi Hashiguchi, Shuji Mizumoto, Kayoko Oguri, Minoru Okayama, Kazuki N. Sugahara, Chun Man Lee, Masayuki Miyasaka, Gerdy B.ten Dam, Toin H.van Kuppevelt
    • Organizer
      6th international Conference on Proteoglycan
    • Place of Presentation
      Aix-les-Bains, France
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Presentation] Identification of Human Hyaluronidase-4 as a Novel Chondroitin Sulfate Hydrolase That Preferentially Cleaves the Specific Linkage in a Highly Sulfated Sequence2009

    • Author(s)
      Shuhei Yamada, Tomoyuki Kaneiwa, Shuji Mizumoto, and Kazuyuki Sugahara
    • Organizer
      6th International Conference on Proteoglycan
    • Place of Presentation
      Aix-les-Bains, France
    • Year and Date
      2009-09-15
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] Structure and biological activities of heparin-like glycosaminoglycan from shrimp heads2009

    • Author(s)
      Jiancheng Chen, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Shuhei Yamada, and Kazuyuki Sugahara
    • Organizer
      2nd Symposium on Structural Analysis of Biological Macromolecules & 7th Japan-Korea Bilateral Symposium on Biological NMR
    • Place of Presentation
      Sapporo
    • Year and Date
      2009-07-27
    • Data Source
      KAKENHI-PROJECT-21590057
  • [Presentation] 組換え体ヒトピアルロニダーゼ-4の基質特異性の研究2008

    • Author(s)
      山田修平
    • Organizer
      第28回日本糖質学会年会
    • Place of Presentation
      つくば
    • Year and Date
      2008-08-19
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Presentation] 組換え体ヒトヒアルロニダーゼ-1および-2の基質特異性の研究2008

    • Author(s)
      山田修平
    • Organizer
      第28回日本糖質学会年会
    • Place of Presentation
      つくば
    • Year and Date
      2008-08-20
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Presentation] 線虫Caenorhabditis elegansにおける新規のコンドロイチン加水分解酵素の同定2008

    • Author(s)
      山田 修平
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-27
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] Structural analysis of chondroitin sulfate and dermatan sulfate in henaran sulfate glucuronyl C5-enimerase-deficient mice2008

    • Author(s)
      山田修平
    • Organizer
      BMB2008(第81回日本生化学会大会・第31回日本分子生物学会年会合同大会)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Presentation] 組換え体ヒトヒアルロニダーゼ-4 の基質特異性の研究2008

    • Author(s)
      山田修平
    • Organizer
      第28回日本糖質学会年会
    • Place of Presentation
      つくば
    • Year and Date
      2008-08-19
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Presentation] Structural analysis ofchondroitin sulfate and dermatansulfate in heparan sulfate glucuronylC5-epimerase-deficient mice、BMB20082008

    • Author(s)
      山田修平
    • Organizer
      第81回日本生化学会大会・第31回日本分子生物学会年会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Presentation] 組換え体ヒトピアルロニダーゼ-1および-2の基質特異性の研究2008

    • Author(s)
      山田修平
    • Organizer
      第28回日本糖質学会年会
    • Place of Presentation
      つくば
    • Year and Date
      2008-08-19
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Presentation] Structural analysis of chondroitin sulfate and dermatan sulfate in heparan sulfate glucuronyl C5-epimerase-deficient mice.2008

    • Author(s)
      山田修平
    • Organizer
      BMB2008(第81回日本生化学会大会・第31回日本分子生物学会年会合同大会)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-20390019
  • [Presentation] 線虫Caenorhabditis elegansにおける新規のコンドロイチン加水分解酵素の同定2008

    • Author(s)
      山田修平
    • Organizer
      第28回日本糖質学会年会
    • Place of Presentation
      つくば
    • Year and Date
      2008-08-19
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Presentation] 線虫Caenorhabditis elegansにおける新規のコンドロイチン加水分解酵素の同定2008

    • Author(s)
      山田修平
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Presentation] Determination of iduronic acid and glucuronic acid in sulfated chondroitin/dermatan hybrid chains by 1H-nuclear magnetic resonance spectroscopy2007

    • Author(s)
      Fuchuan Li & Shuhei Yamada & Makiko Sugiura & Kazuyuki Sugahara
    • Organizer
      The 127th Japanease Pharmaceutical Symposium
    • Place of Presentation
      Toyama
    • Year and Date
      2007-03-28
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] 抗コンドロイチン硫酸D(CS-D)抗体MO-225が認識するCS-E由来のオリゴ糖の構造解析2007

    • Author(s)
      山田 修平
    • Organizer
      第44回 日本生化学会北海道支部例会
    • Place of Presentation
      札幌
    • Year and Date
      2007-07-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] サメ軟骨コンドロイチン硫酸由来の八糖の構造解析と抗体のエピトープ解析への応用2007

    • Author(s)
      山田修平
    • Organizer
      第27回日本糖質学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2007-08-03
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Presentation] Chondroitinase-Mediated Degradation of Rare 3-O-Sulfated Glucuronic acid in Functional Oversulfated Chondroitin Sulfate Chains.2007

    • Author(s)
      D. Fongmoon, A.K. Shetty, B. Basappa, S. Yamada, M. Sugiura, P. Kongtawelert, and K. Sugahara
    • Organizer
      Glycol9 (XIX International Symposium on Glycoconjugates)
    • Place of Presentation
      Cairns
    • Year and Date
      2007-07-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] 単クローン抗体MO-225が認識するコンドロイチン硫酸E由来のオリゴ糖の構造解析2007

    • Author(s)
      山田 修平
    • Organizer
      第27回日本糖質学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2007-08-03
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] Fate and Detection of Rare 3-O-Sulfated Glucuronic Acid-containing Disaccharides in Various Chondroitin Sulfate Preparations2007

    • Author(s)
      Ajaya Kumar Shetty, Duriya Fongmoon, Basappa, Shuhei Yamada, Kazuyuki Sugahara
    • Organizer
      The 127th Japanease Pharmaceutical Symposium
    • Place of Presentation
      Toyama
    • Year and Date
      2007-03-28
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] Determination of iduronic acid and glucuronic acid in sulfated chondroitin/dermatan hybrid chains by 1H-nuclear magnetic resonance spectroscopy2007

    • Author(s)
      Fuchuan Li & Shuhei Yamada & Makiko Sugiura & Kazuyuki Sugahara
    • Organizer
      BMB2007
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-12-12
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] 単クローン抗体MO-225 が認識するコンドロイチン硫酸E由来のオリゴ糖の構造解析2007

    • Author(s)
      山田修平
    • Organizer
      第27回日本糖質学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2007-08-03
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Presentation] The epitope structure recognized by anti-chondroitin sulfate antibodies2007

    • Author(s)
      Kazuyuki Sugahara, Sarama S. Deepa, Kittiwan Kalayanamitra, Peraphan Pothacharoen, Prachya Kongtawelert, Yumi Ito, Tadahisa M Ikami, Basappa, Shuhei Yamada, Shigeyuki Fukui, Tim Hardingham, Veronique Blanchard, Franck Chevalier, Anne Imberty, Bas R. Leeflang, Johannis P. Kamerling, Tomohide Hattori, Nobuhiro Hukushima
    • Organizer
      The 27^<th> Japanease Carbohydrate Symposium
    • Place of Presentation
      Fukuoka
    • Year and Date
      2007-08-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] コンドロイチン硫酸(CS)/デルマタン硫酸(DS)中のイズロン酸(IdoA)とグルクロン酸(GlcA)の1H NMR解析による定量2007

    • Author(s)
      山田 修平
    • Organizer
      日本薬学会第127年会
    • Place of Presentation
      富山
    • Year and Date
      2007-03-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] Novel Sulfated Octa- and Decasaccharides from Squid Cartilage Chondroitin Sulfate E: Sequencing and Application for Determination of the Epitope Structure of the Monoclonal Antibody MO-2252007

    • Author(s)
      Sarama Sathyaseelan Deepa, Kittiwan Kalayanamitra, Yumi Ito, Prachya Kongtawelert, Shigeyuki Fukui, Shuhei Yamada, Tadahisa Mikami, Kazuyuki Sugahara
    • Organizer
      The 27^<th> Japanease Carbohydrate Symposium
    • Place of Presentation
      Fukuoka
    • Year and Date
      2007-08-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] コンドロイチン硫酸(CS)/デルマタン硫酸(DS)中のグルクロン酸(GlcA)とイズロン酸(IdoA)の1H NMR解析による定量2007

    • Author(s)
      山田 修平
    • Organizer
      BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会)
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-12
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] 抗コンドロイチン硫酸D(CS-D)抗体MO-225が認識するCS-E由来のオリゴ糖の構造解析2007

    • Author(s)
      山田修平
    • Organizer
      第44回日本生化学会北海道支部例会
    • Place of Presentation
      札幌
    • Year and Date
      2007-07-06
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Presentation] サメ軟骨コンドロイチン硫酸由来の八糖の構造解析と抗体のエピトープ解析への応用2007

    • Author(s)
      山田 修平
    • Organizer
      第27回日本糖質学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2007-08-03
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] Structural determination of novel sulfated octasaccharides isolated from chondroitin sulfate of shark cartilage and their application for characterizing monoclonal antibody epitopes2007

    • Author(s)
      Sarama S. Deepa, Shuhei Yamada, Shigeyuki Fukui, Kazuyuki Sugahara
    • Organizer
      The 27^<th> Japanease Carbohydrate Symposium
    • Place of Presentation
      Fukuoka
    • Year and Date
      2007-08-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] Chondroitinase-Mediated Degradation of Rare 3-O-Sulfated Glucuronic Acid in Functional Oversulfated Chondroitin Sulfate Chains2007

    • Author(s)
      Ajaya K Shetty, Duriya Fongmoon, Basappa, Shuhei Yamada, Makiko Sugiura, Prachya Kongtawelert and Kazuyuki Sugahara
    • Organizer
      BMB2007
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-12-12
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] Development of Analytical Method to Detect Rare 3-O-Sulfated Glucuronic Acid-containing Disaccharides in Various Chondroitin Sulfate Preparations2006

    • Author(s)
      Duriya Fongmoon, Ajaya Kumar Shetty, Basappa, Shuhei Yamada, Kazuyuki Sugahara
    • Organizer
      The 43th Japanease Biochemistry Symposium (Hokkaido Branch)
    • Place of Presentation
      Sapporo
    • Year and Date
      2006-11-03
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] コンドロイチン硫酸Eは単純ヘルペスウィルスのglycoprotein Cに直接結合し、抗ウィルス活性を発揮する2006

    • Author(s)
      山田 修平
    • Organizer
      第43回日本生化学会北海道支部例会
    • Place of Presentation
      札幌
    • Year and Date
      2006-11-03
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] Glycosaminoglycans in Hydra magnipapillata.2006

    • Author(s)
      山田 修平
    • Organizer
      Extracellular Glycomatrix in Health and Disease.
    • Place of Presentation
      淡路島
    • Year and Date
      2006-06-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] Development of Analytical Method to Detect Rare 3-O-Sulfated Glucuronic Acid-containing Disaccharides in Various Chondroitin Sulfate Preparations2006

    • Author(s)
      Duriya Fongmoon, Ajaya Kumar Shetty, Basappa, Shuhei Yamada, Kazuyuki Sugahara
    • Organizer
      XXVIth Japanease Carbohydrate Symposium.
    • Place of Presentation
      Sendai
    • Year and Date
      2006-08-24
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] 単純ヘルペスウィルスの感染に関わるコンドロイチン硫酸E2006

    • Author(s)
      山田 修平
    • Organizer
      第26回日本糖質学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2006-08-24
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] Chondroitin Sulfate E Directly Interacts with Herpes Simplex Virus Attachment Glycoprotein C and Exhibits Potent Antiviral Activity2006

    • Author(s)
      Satomi Naito, Shuhei Yamada, Kicki Bergefall, Edward Trybala, Maria Johansson, Torn Uyama, Hiroshi Kitagawa, Kazuyuki Sugahara, Tomas Bergstrom
    • Organizer
      20^<th> IUBMB International Congress of Biochemistry and Molecular Biology and 11<th> FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Year and Date
      2006-06-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] Glycosaminoglycans in Hydra magnipapillata2006

    • Author(s)
      Shuhei Yamada, Hideto Morimoto, Toshitaka Fujisawa, Kazuyuki Sugahara
    • Organizer
      Extracellular Glycomatrix in Health and Disease
    • Place of Presentation
      Awaji
    • Year and Date
      2006-06-15
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390030
  • [Presentation] コンドロイチン硫酸(CS)/デルマタン硫酸(DS)中のグルクロン酸(GlcA)とイズロン酸(IdoA)の1HNMR解析による定量2004

    • Author(s)
      山田修平
    • Organizer
      BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会)
    • Place of Presentation
      横浜
    • Year and Date
      2004-12-12
    • Data Source
      KAKENHI-PROJECT-19590052
  • [Presentation] Novel CS-E-Binding Proteins in Mouse Brain That May Be Involved in the Neurite Outgrowth Promoting Mechanism through Chondroitin Sulfate E-Type

    • Author(s)
      Kazuyuki Sugahara, Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, and Kosei Takeuchi
    • Organizer
      Gordon Research Conference on Proteoglycans 2014
    • Place of Presentation
      Andover, USA
    • Year and Date
      2014-07-07 – 2014-07-10
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] Mass preparation of oligosaccharides with intestinal absorption capacity by hydrolysis of chondroitin sulfate polysaccharides with subcritical water microreaction system

    • Author(s)
      Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, and Nobuyuki Miyamoto
    • Organizer
      The 13th International Conference on Functional and Medical Foods with Bioactive Compounds: Science and Practical Applications”
    • Place of Presentation
      The Kyoto Prefectural University of Medicine (京都)
    • Data Source
      KAKENHI-PROJECT-23390016
  • [Presentation] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences involved in brain development

    • Author(s)
      ○Shuji Mizumoto, Saori Murakoshi, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fuku5, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
    • Organizer
      2012年度 包括型脳科学研究推進支援ネットワーク・夏のワークショップ
    • Place of Presentation
      仙台国際センター(仙台)
    • Data Source
      KAKENHI-PROJECT-23790066
  • [Presentation] サメヒレ軟骨コンドロイチン硫酸由来の新規な六糖配列の単離

    • Author(s)
      ◯水本秀二, 村越早織, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, 福井成行, Prachya Kongtawelert, 山田修平, 菅原一幸
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Data Source
      KAKENHI-PROJECT-23790066
  • [Presentation] Expression Analysis of Hyaluronidases in the Mouse Brain during Development

    • Author(s)
      Yuka Oiwa, Shuji Mizumoto, Ryoji Kojima, Tadashi Nagamatsu, Shuhei Yamada
    • Organizer
      Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research “Glycans in Neuroscience”
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2014-11-16 – 2014-11-18
    • Data Source
      KAKENHI-PROJECT-24590071
  • [Presentation] Novel CS-E-Binding Proteins in Mouse Brain That May Be Involved in the Neurite Outgrowth Promoting Mechanism through Chondroitin Sulfate E-Type

    • Author(s)
      Kazuyuki Sugahara, Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, and Kosei Takeuchi
    • Organizer
      Gordon Research Conference on Proteoglycans 2014
    • Place of Presentation
      Andover, USA
    • Year and Date
      2014-07-07 – 2014-07-10
    • Data Source
      KAKENHI-PUBLICLY-26110719
  • 1.  SUGAHARA Kazuyuki (60154449)
    # of Collaborated Projects: 21 results
    # of Collaborated Products: 148 results
  • 2.  MIZUMOTO Shuji (40443973)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 180 results
  • 3.  KITAGAWA Hiroshi (40221915)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 1 results
  • 4.  MIKAMI Tadahisa (20330425)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 2 results
  • 5.  MIYAKE Noriko (40523494)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 17 results
  • 6.  KOSHO Tomoki (90276311)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 33 results
  • 7.  IKEGAWA Shiro (30272496)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 8.  MATSUMOTO Naomichi (80325638)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 18 results
  • 9.  ASANO Masahide (50251450)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  YOSHIZAWA TAKAHIRO (40713392)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 11.  Janecke Andreas
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 12.  YAMASHITA Tadashi (30220338)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  NOMIZU Motoyoshi (00311522)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TAYA Choji (90175456)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MIKAMI Tadahisa (20033425)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  Takahashi Iwao (20552912)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  木下 亜希子 (30289037)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  角田 佳充 (00314360)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  岡田 尚巳 (00326828)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  野村 義宏 (10228372)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 21.  岳 鳳鳴 (20532865)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 22.  松本 健一 (30202328)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 23.  上原 将志 (30748108)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  渡邉 敬文 (50598216)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 25.  高橋 淳 (60345741)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 26.  宮田 真路 (60533792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 27.  高野 亨子 (70392420)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  笠原 優子 (90391911)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 29.  山口 智美 (90802835)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  林 正徳 (20624703)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  YOSHIDA Keiichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  NAKAJIMA Motowo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  BASAPPA
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  YIP George W.C.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  STEFAN Mundlos
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 36.  LIHADH Al-gazali
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  KATRIN Hoffmann
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  ANDREAS Janecke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  BAO Xingfeng
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  LI Fuchuan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  Nürnberg Peter
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  Kennerknecht Ingo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  Vodopiutz Julia
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  Kornak Uwe
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  FURUICHI Tatsuya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  WATANABE Kota
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 47.  武田 和樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 48.  岡田 尚已
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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