habuchi osami 羽渕脩躬

… Alternative Names

Researcher Number	90024067
Other IDs
External Links
Affiliation (Current)	2020: 愛知医科大学, 公私立大学の部局等, 客員教授
Affiliation (based on the past Project Information) *help	2016 – 2018: 愛知医科大学, 公私立大学の部局等, 客員教授 2013 – 2014: 愛知医科大学, 公私立大学の部局等, その他 2011 – 2012: 愛知医科大学, 公私立大学の部局等, 客員教授 1994 – 2007: 愛知教育大学, 教育学部, 教授 2006: Aichi University, Education, Professor
Review Section/Research Field	Principal Investigator Structural biochemistry / Functional biochemistry / Pain science Except Principal Investigator Functional biochemistry / Biological Sciences
Keywords	Principal Investigator コンドロイチン硫酸 / 硫酸転移酵素 / プロテオグリカン / GalNAc4S-6ST / クローニング / デルマタン硫酸 / グリコサミノグリカン / コンドロイチン硫酸E / イカ軟骨 / C4ST … More Except Principal Investigator プロテオグリカン / コンドロイチン硫酸 / ヘパラン硫酸 / スルフォトランスフェラーゼ / N-グリコリルノイラミン酸 / CMP-NeuAc水酸化酵素 / セラミド / エンドグリコセラミダーゼ / 硫酸転移酵素 / シアリルルイスA / ビトロネクチン / CMP-NeuAc水酸化酸素 / ギラン・バレー症候群 / がん関連抗原 / シアリルLe^a抗原 / レクチン / ガラクトース転移酵素 / Tn抗原 / アネキシンファミリー / シンデカン / プロテインホスファターゼ / ミッドカイン / 異種抗原 / N-アセチルガラクトサミニルトランスフェラーゼ / 糖鎖シグナル / スルホトランスフェラーゼ / ガングリオシド / L-セレクチン / フコシダーゼ / 糖鎖硫酸化 / シグナル入力 / コンドロイチン-6-硫酸 / 遺伝子ノックアウト / N-アセチルグルコサミン / ノックアウトマウス / ストローマ細胞 / 第9染色体 / FISH / コンドロイチン6-スルフォトランスフェラーゼ / マウス / chondroitin 6-sulfate / sulfotransferase / gene knockout / N-acetylglucosamine / 細胞増殖因子 / 形態形成因子 / 濃度勾配 / グリコサミノグリカン / 遺伝子欠損マウス / 形態形成因子(モルフォゲン) / コンドロイチン / 細胞外マトリックス / Heparan sulfate / Cell growth factors / Morphogen / Concentration gradient / Chondroitin sulfate / Proteoglycans / Glycosaminoglycans / Mutant mouse Less

炎症・疼痛制御における肥満細胞、マクロファージ高硫酸化プロテオグリカンの機能解明Principal InvestigatorOngoing
- Principal Investigator
  
  羽渕脩躬
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Aichi Medical University
Study on the physiological and pathological function of highly-sufated chondroitin/dermatan sulfatePrincipal Investigator
- Principal Investigator
  
  HABUCHI Osami
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Aichi Medical University
Biosynthesis and biological roles of specific sulfation pattern of chondroitin sulfatePrincipal Investigator
- Principal Investigator
  
  HABUCHI Osami
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Aichi University of Education
Spatio-temporal regulation of morphogenesis by heparan sulfate chains
- Principal Investigator
  
  KIMATA Koji
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Aichi Medical University
Study on the function and control of sulfotransferases involving the synthesis of divergent structure of chondroitin sulfatePrincipal Investigator
- Principal Investigator
  
  HABUCHI Osami
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Aichi University of Education
Study on the biological function of glycoconjugatesPrincipal Investigator
- Principal Investigator
  
  HABUCHI Osami
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Aichi University of Education
糖鎖シグナルによる細胞間コミュニケーションの制御
- Principal Investigator
  
  MURAMATSU Takashi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nagoya University
Purification and molecular cloning of chondroitin 4-sulfotransferasePrincipal Investigator
- Principal Investigator
  
  HABUCHI Osami
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Aichi University of Education
Functional Analysis of chondroitin sulfate by knockout technique
- Principal Investigator
  
  MURAMATSU Hisako
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University
グリコサミノグリカン合成に関与する硫酸転移酵素遺伝子の構造と機能Principal Investigator
- Principal Investigator
  
  羽渕脩躬
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Aichi University of Education
グリコサミノグリカン合成に関与する硫酸転移酵素遺伝子の構造と機能Principal Investigator
- Principal Investigator
  
  羽渕脩躬
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Aichi University of Education
糖鎖発現の制御因子
- Principal Investigator
  
  鈴木明身
- Project Period (FY)
  1993 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

[Book] Chapter 44, Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15) in Handbook of Glycosyltransferases and Related Genes N. Taniguchi et al. (eds.),2014
- Author(s)
  Habuchi O
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-23570175
[Book] Chapter 43, Carbohydrate (Chondroitin 4) Sulfotransferase 11-13 (CHST11-13) in Handbook of Glycosyltransferases and Related Genes N. Taniguchi et al. (eds.)2014
- Author(s)
  Habuchi O
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-23570175
[Book] Chapter 41, Carbohydrate (Chondroitin 6) Sulfotransferase 3; Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 7 (CHST3,7) in Handbook of Glycosyltransferases and Related Genes N. Taniguchi et al. (eds.)2014
- Author(s)
  Habuchi O
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-23570175
[Book] Chapter 42, Carbohydrate (Keratan Sulfate Gal-6) Sulfotransferase 1 (CHST1) in Handbook of Glycosyltransferases and Related Genes N. Taniguchi et al. (eds.)2014
- Author(s)
  Habuchi O
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-23570175
[Book] Determination of Substrate Specificity of Sulfotransferases and Glycosyltransferases(Proteoglycans). Methods Enzymol. vol.416. Section 5, Chapter 142009
- Author(s)
  Habuchi, H., Habuchi, O., Uchimura, K., Kimata. K., and Muramatsu, T
- Total Pages
  19
- Publisher
  Academic Press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Book] Knockout Mic eand Proteoglycans in COMPREHENSIVE GLYCOSCIENCE.(Kamerling, 7.P.etal.eds.)Vol.3, Chapter4.10, 159-1912007
- Author(s)
  Kimata, K., Habuchi, O., Habuchi, H., and Watanabe, H
- Total Pages
  32
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-18570125
[Book] Knockout Mice and Proteoglycans in COMPREHENSIVE GLYCOSCIENCE.(Kamerling, J. P., et. al.eds.)Vol.3, Chapter 4.10, 159-1912007
- Author(s)
  Kimata, K., Habuchi, O., Habuchi, H., and Watanabe, H
- Total Pages
  32
- Publisher
  Elsevier
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Book] 4.糖鎖機能解析 9 発生・分化・形態形成 9.6 形態形成におけるヘパラン硫酸プロテオグリカンの機能.未来を拓く糖鎖科学.2005
- Author(s)
  羽渕弘子, 木全弘治.
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-14082206
[Book] 第1章基礎編 3.糖鎖の細胞生物学 4)グリコサミノグリカンの硫酸化と疾患.遺伝子医学MOOK3 糖鎖と病気.2005
- Author(s)
  羽渕脩躬, 羽渕弘子, 木全弘治.
- Publisher
  株式会社メディドゥ
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Mice deficient in N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase exhibit enhanced liver fibrosis and delayed recovery from fibrosis in carbon tetrachloride-treated mice.2016
- Author(s)
  Habuchi H, Ushida T, Habuchi O.
- Journal Title
  
  Heliyon2
  
  Volume: 2
- DOI
  10.1016/j.heliyon.2016.e00138
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08999
[Journal Article] Chondroitin sulfate-E mediates estrogen-induced osteoanabolism.2015
- Author(s)
  Koike T, Mikami T, Shida M, Habuchi O, Kitagawa H.
- Journal Title
  
  Sci. Rep.
  
  Volume: 5 Pages: 8994-8994
- DOI
  10.1038/srep08994
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23570175, KAKENHI-PROJECT-24590132, KAKENHI-PROJECT-25293014, KAKENHI-PLANNED-23110003
[Journal Article] Sulfated Glycosaminoglycans Control the Extracellular Trafficking and the Activity of the Metalloprotease Inhibitor TIMP-3.2014
- Author(s)
  Troeberg L, Lazenbatt C, Anower-E-Khuda MF, Freeman C, Federov O, Habuchi H, Habuchi O, Kimata K, Nagase H.
- Journal Title
  
  Chem Biol.
  
  Volume: 21 Pages: 1300-1309
- DOI
  10.1016/j.chembiol.2014.07.014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23570148, KAKENHI-PROJECT-23570175
[Journal Article] Heparan sulfate 6-O-sulfotransferase isoform-dependent regulatory effects of heparin on the activities of various proteases in mast cells and the biosynthesis of 6-O-sulfated heparin.2013
- Author(s)
  Anower-E-Khuda MF, Habuchi H, Nagai N, Habuchi O, Yokochi T, Kimata K.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Pages: 3705-3717
- DOI
  10.1074/jbc.m112.416651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590296, KAKENHI-PROJECT-23570148, KAKENHI-PROJECT-23570175
[Journal Article] Glycosaminoglycans in the blood of hereditary multiple exostoses patients: Half reduction of heparan sulfate to chondroitin sulfate ratio and the possible diagnostic application2013
- Author(s)
  Anower-E-Khuda MF, Matsumoto K, Habuchi H, Morita H, Yokochi T, Shimizu K, Kimata K.
- Journal Title
  
  Glycobiology
  
  Volume: 23 Pages: 865-76
- DOI
  10.1093/glycob/cwt024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570148, KAKENHI-PROJECT-23570175
[Journal Article] Involvement of heparan sulfate 6-O-sulfation in regulation of energy metabolism and alteration of thyroid hormone levels in male mice2013
- Author(s)
  Nagai N, Habuchi H, Sugaya N, Nakamura M, Imamura T, Watanabe H, Kimata K.
- Journal Title
  
  Glycobiology
  
  Volume: 23 Pages: 980-92
- DOI
  10.1093/glycob/cwt037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590296, KAKENHI-PROJECT-23570148, KAKENHI-PROJECT-23570175, KAKENHI-PROJECT-23659556, KAKENHI-PROJECT-25293096
[Journal Article] Heparan sulfate 6-O-sulfotransferase isoform-dependent regulatory effects of heparin on the activities of various proteases in mast cells and the biosynthesis of 6-O-sulfated heparin2012
- Author(s)
  Md. Ferdous Anower-E-Khuda, Hiroko Habuchi, Naoko Nagai, Osami Habuchi, Takashi Yokochi, and Koji Kimata
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Pages: 3705-3717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570175
[Journal Article] A sulfated carbohydrate epitope inhibits axon regeneration after injury2012
- Author(s)
  Brown JM, Xia J, Zhuang B, Cho KS, Rogers CJ, Gama CI, Rawat M, Tully SE, Uetani N, Mason DE, Tremblay ML, Peters EC, Habuchi O, Chen DF, Hsieh-Wilson LC
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 109 Pages: 4768-4773
- DOI
  10.1073/pnas.1121318109
- Data Source
  KAKENHI-PROJECT-23570175
[Journal Article] Expression of sulfotransferases involved in the biosynthesis of chondroitin sulfate E in the bone marrow derived mast cells2008
- Author(s)
  Ohtake, S., Kondo, S., Morisaki, T., Matsumura, K., Kimata, K, Habuchi, O
- Journal Title
  
  Biochim. Biophys. Ada 1780
  
  Pages: 687-695
- NAID
  120002061381
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] Expression of sulfotransferases involved in the biosynthesis of chondroitin sulfate E in the bone marrow derived mast cells2008
- Author(s)
  Ohtake, S., Kondo, S., Morisaki, T., Matsumura, K., Kimata, K., and Habuchi, O.
- Journal Title
  
  Biochim.Biophys.Acta 1780
  
  Pages: 687-695
- NAID
  120002061381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] Expression of sulfotransferases involved in the biosynthesis of chondroitin sulfate E in the bone marrow derived mast cells2008
- Author(s)
  Ohtake, S., Kondo, S., Morisaki, T., Matsumura, K., Kimata, K., and Habuchi, O.
- Journal Title
  
  Biochim. Biophys. Acta 1780
  
  Pages: 687-695
- NAID
  120002061381
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] Molecular cloning of squid N-acetylgalactosamine 4-sulfate 6-0-sulfotransferase and synthesis of a unique chondroitin sulfate containing E-D hybrid tetrasaccharide structure by the recombinant enzyme2007
- Author(s)
  Yamaguchi, T., Ohtake, S., Kimata, K., Habuchi, O
- Journal Title
  
  Glycobiology 17
  
  Pages: 1365-1376
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] ヘパラン硫酸プロテオグリカンと形態形成2007
- Author(s)
  羽渕弘子、羽渕脩躬、木全弘治
- Journal Title
  
  THE LUNG perspectives(メディカルレビュー社) 15
  
  Pages: 75-81
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] Molecular cloning of squid N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase and synthesis of a unique chondroitin sulfate containing E-D hybrid tetrasaccharide structure by the recombinant enzyme,2007
- Author(s)
  Yamaguchi, T., Ohtake, S., Kimata, K., and Habuchi, O.
- Journal Title
  
  Glycobiology, 17
  
  Pages: 1365-1376
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] ヘパラン硫酸プロテオグリカンと形態形成2007
- Author(s)
  羽渕弘子, 羽渕脩躬, 木全弘治
- Journal Title
  
  THE LUNG perspectives(メディカルレビユー社) 15
  
  Pages: 75-81
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] Molecular cloning of squidN-acetylgalactosamine4-sulfate 6-O-sulfotransferase and synthesis of a unique chondroitin sulfate containing E-D hvbrid tetrasaccharide structure by the recombinant enzyme2007
- Author(s)
  Yamaguchi, T., Ohtake, S., Kimata, K., and Habuchi, O.
- Journal Title
  
  Glycobiology 17
  
  Pages: 1365-1376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] Heparan sulfate proteoglycans and morphogenesis (Japanese)2007
- Author(s)
  H. Habuchi, O. Habuchi, K. Kimata
- Journal Title
  
  THE LUNG perspectives 15,1
  
  Pages: 75-81
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] The utility of formalin-fixed paraffm-embedded tissue blocks for quantitative analysis of N-acetylgalactosamine 4-sulfate 6-0-sulfotransferase mRNA expressed by colorectal cancer cells2007
- Author(s)
  Ito, Y, Watanabe, M., Nishizawa, T, Omachi, T., Kobayashi, T., Habuchi, O., Nakayama
- Journal Title
  
  Acta Histochem. Cytochem 40
  
  Pages: 53-59
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] The utility of formalin-fixed paraffin-embeded tissue blocks for quantitative analysis of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase mRNA expressed by colorectal cancer cells2007
- Author(s)
  Ito, Y., Watanabe, M., Nishizawa, T., Omachi, T., Kobayashi, T., Habuchi, O., and Nakayama
- Journal Title
  
  Acta Histochem.Cytochem 40
  
  Pages: 53-59
- NAID
  110006633414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] Mice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation and late embryonic lethality.2007
- Author(s)
  Habuchi H
- Journal Title
  
  J. Biol. Chem. 282巻・21号
  
  Pages: 15578-15588
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Essential role of heparan sulfate 2-O-sulfotransferase in chick limb bud patterning and development.2007
- Author(s)
  Kobayashi T, Habuchi H, Tamura K, Ide H, Kimata K
- Journal Title
  
  J Biol Chem 282
  
  Pages: 19589-19597
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] The utility of formalin-fixed paraffin-embedded tissue blocks for quantitative analysis of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase mRNA expressed by colorectal cancer cells2007
- Author(s)
  Ito, Y., Watanabe, M., Nishizawa, T., Omachi, T., Kobayashi, T., Habuchi, O., and Nakayama
- Journal Title
  
  Acta Histochem. Cytochem 40
  
  Pages: 53-59
- NAID
  110006633414
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] Knockout Mice and Proteoglycans. Comprehensive Glycoscience, - From Chemistry to Systems Biology (Ed.-in-Chief, J P Kamerling ; Subject Ed., A.Suzuki)2007
- Author(s)
  Kimata K, Habuchi O, Habuchi H, Watanabe H
- Journal Title
  
  Elsevier Vol 4
  
  Pages: 33-33
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Specific and flexible roles of heparan sulfate modifications in Drosophila FGF signaling.2006
- Author(s)
  Kamimura K, Koyama T, Habuchi H, Ueda R, Masu M, Kimata K, Nakato H
- Journal Title
  
  J Cell Biol 174
  
  Pages: 773-778
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Determination of Substrate Specificity of Sulfotransferases and Glycosyltransferases (Proteoglycans)2006
- Author(s)
  Habuchi, H., Habuchi, O., Uchimura, K., Kimata.K., Muramatsu, T.
- Journal Title
  
  Methods Enzymol 416
  
  Pages: 225-243
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] Determination of Substrate Specificity of Sulfotransferases and Glycosyltransferases (Proteoglycans)2006
- Author(s)
  Habuchi, H., Habuchi, O., Uchimura, K., Kimata. K, Muramatsu, T
- Journal Title
  
  Methods Enzymo 416,5,14
  
  Pages: 225-243
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] N-linked oligosaccharides on chondroitin 6-sulfotransferase-1 are required for production of the active enzyme, Golgi localization and the sulfotransferase activity toward keratan sulfate.2006
- Author(s)
  Yusa, A., Kitajima, K., Habuchi, O.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 20393-20403
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] Versican/PG-M regulates chondrogenesis as an extracellular matrix molecule crucial for mesenchymal condensation.2006
- Author(s)
  Kamiya N, Watanabe H, Habuchi H, Takagi H, Shinomura T, Shimizu K, Kimata K
- Journal Title
  
  . J Biol Chem. 281
  
  Pages: 2390-2400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] N-linked oligosaccharides on chondroitin 6-sulfotransferase-1 are required for production of the active enzyme, Golgi localization and the sulfotransferase activity toward keratan sulfate.2006
- Author(s)
  Yusa, A., Kitajima, K., and Habuchi, O.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 20393-20403
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] N-linked oligosaccharides on chondroitin 6-sulfotransferase-1 are required for production of the active enzyme, Golgi localization and the sulfotransferase activity toward keratan sulfate2006
- Author(s)
  Yusa, A., Kitajima, K., Habuchi, O
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 20393-20403
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Journal Article] Heparin regulates vascular endothelial growth factorl65-dependent mitogenic activity, tube formation, and its receptor phosphorylation of human endothelial cells. Comparison of the effects of heparin and modified heparins.2005
- Author(s)
  Ashikari-Hada S, Habuchi H, Kariya Y, Kimata K
- Journal Title
  
  J Biol Chem 174
  
  Pages: 31508-31515
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Heparin regulates vascular endothelial growth factor165-dependent mitogenic activity, tube formation, and its receptor phosphorylation of human endothelial cells. Comparison of the effects of heparin and modified heparins.2005
- Author(s)
  S.Ashikari-Hada, H.Habuchi, et al.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 31508-31515
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Sulfation pattern in glycosaminoglycan : Does it have a code?2004
- Author(s)
  H.Habuchi, O.Habuchi, et al.
- Journal Title
  
  Glycoconj J 21
  
  Pages: 47-52
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Stem domains of heparan sulfate 6-O-sulfotransferase are required for Golgi localization, oligomer formation and enzyme activity.2004
- Author(s)
  N.Nagai, H.Habuchi, et al.
- Journal Title
  
  J Cell Sci 117
  
  Pages: 3331-3341
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Characterization of growth factor-binding structures in heparin/heparan sulfate using an octasaccharide library2004
- Author(s)
  Ashikari-Hada S, Habuchi H, Kariya Y, Itoh N, Reddi AH, Kimata K
- Journal Title
  
  J Biol Chem 279
  
  Pages: 12346-12354
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Characterization of growth factor-binding structures in heparin/heparan sulfte using an octasaccharide library.2004
- Author(s)
  S.Ashikari-Hada, H.Habuchi, et al.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 12346-12354
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Heparan sulfate 6-o-sulfotransferase is essential for muscle development in zebrafish.2003
- Author(s)
  Bink RJ, Habuchi H, Lele Z, Dolk E, Joore J, Rauch QJ, Geisler R, Wilson SW, den Hertog J, Kimata K, Zivkovic D
- Journal Title
  
  J Biol Chem 278
  
  Pages: 31118-31127
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Journal Article] Knockout Mice and Proteoglycans in
- Author(s)
  Kimata, K. Habuchi, O. Habuchi, H. Watanabe, H
- Journal Title
  
  COMPREHENSIVE GLYCOSCIENCE.(Kamerling, J. P. et. al. eds.) 3,4,10
  
  Pages: 159-191
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Patent] ヘパラン硫酸6-O-硫酸基転移酵素2006
- Inventor(s)
  羽渕弘子, 羽渕脩躬
- Industrial Property Rights Holder
  生化学工業
- Acquisition Date
  2006-06-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Patent] ノックアウト動物2005
- Inventor(s)
  木全弘治, 羽渕弘子
- Industrial Property Rights Holder
  生化学工業
- Industrial Property Number
  2005-058162
- Filing Date
  2005-03-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Patent] ヘパラン硫酸 2-O-硫酸基転移酵素2005
- Inventor(s)
  小林政, 羽渕弘子, 羽
- Industrial Property Rights Holder
  生化学工業
- Acquisition Date
  2005-04-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Patent] 硫酸基転移酵素阻害剤2004
- Inventor(s)
  木全弘治, 羽渕弘子
- Industrial Property Rights Holder
  生化学工業
- Industrial Property Number
  2005-506231
- Filing Date
  2004-11-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14082206
[Presentation] MIA誘起OAマウスへの骨髄由来マスト細胞（BMMC）移入による疼痛発症にはトリプターゼの受容体であるPAR2活性化が関与する2019
- Author(s)
  羽渕弘子、泉仁、團隼兵、牛田享宏、池内昌彦、羽渕脩躬
- Organizer
  第41回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-16K08999
[Presentation] 変形性関節症モデルマウスにおけるマスト細胞の疼痛誘起作用2018
- Author(s)
  羽渕弘子、泉仁、團隼兵、牛田享宏、池内昌彦、羽渕脩躬
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08999
[Presentation] 変形性関節症モデルにおけるマスト細胞の役割2016
- Author(s)
  泉仁、羽渕弘子、羽渕脩躬、池内昌彦、牛田享宏
- Organizer
  第9回運動器疼痛学会
- Place of Presentation
  御茶ノ水ソラシティカンファレンスセンター
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-16K08999
[Presentation] 高硫酸化デルマタン硫酸は肝繊維化の回復に寄与2013
- Author(s)
  羽渕弘子、羽渕脩躬
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23570175
[Presentation] Heparan sulfate 6-O-sulfotransferase isoform-dependent regulatory effects of heparin on the activities of various proteases in mast cells and the biosynthesis of 6-O-sulfated heparin.2012
- Author(s)
  Md.Ferdous Anower-E-Khuda, Hiroko Habuchi, Naoko Nagai, Takashi Yokochi, Osami Habuchi, Noriko Sugaya, Koji Kimata
- Organizer
  Gordon Research Conference (Proteoglycans )
- Place of Presentation
  Proctor Academy, Andover, NH, USA
- Data Source
  KAKENHI-PROJECT-23570175
[Presentation] 6-O-sulfation of heparin is essential for storage and activities of proteases in connective tissue mast cells2011
- Author(s)
  Md Ferdous Anower-E-Kuda, Hiroko Habuchi, Naoko Nagai, Takashi Yokochi, Osami Habuchi, Noriko Sugaya, Koji Kimata
- Organizer
  日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23570175
[Presentation] Functonal analysis of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase2007
- Author(s)
  O. Habuchi, S. Ohtake, S, Rondo, T. Yamaguchi, N. Kusakabe, T. Ito, H. Habuchi, K. Kimata
- Organizer
  Joint meeting of 80th Annual Scientific Meeting of the Japanese Biochemical Society and 30th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Pacifico Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Presentation] イカのリコンビナント硫酸転移酵素によるE-D4糖を含むコンドロイチン硫酸の合成2007
- Author(s)
  山口照由、大竹しおり、木全弘治、羽渕脩躬
- Organizer
  第27回日本糖質学会年会
- Place of Presentation
  九州大学医学部百年講堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Presentation] Synthesis of chondroitin sulfate containing an E-D tetrasaccharide structure by the recombinant squid sulfotransferase2007
- Author(s)
  T. Yamaguchi, S. Ohtake, K. Kimata, O. Habuchi
- Organizer
  27th Annual Conference of The Japanese Society of Carbohydrate Research
- Place of Presentation
  Kyushu University
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Presentation] N-アセチルガラクトサミン4-硫酸6-O-硫酸転移酵素の機能解析2007
- Author(s)
  羽渕脩躬、大竹しおり、近藤幸子、山口照由、日下部教子、伊藤達郎、羽渕弘子、木全弘治
- Organizer
  第80回日本生化学大会、第30回日本分子生物学会年会合同大会
- Place of Presentation
  パシフィコ横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Presentation] Thrombomodulinの機能を持つ高硫酸化コンドロイチン硫酸の酵素的合成2007
- Author(s)
  日下部教子、大竹しおり、山口照由、羽渕弘子、羽渕脩躬
- Organizer
  第80回日本生化学大会、第30回日本分子生物学会年会合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18570125
[Presentation] Thrombomodulinの機能を持つ高硫酸化コンドロイチン硫酸の酵素的合成2007
- Author(s)
  日下部教子、大竹しおり、山口照由、羽渕弘子、羽渕脩躬
- Organizer
  第80回日本生化学会、第30回日本分子生物学会年会合同大会
- Place of Presentation
  パシフィコ横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Presentation] Enzymatic synthesis of highly sulfated chondroitin sulfate that mimics thrombomoduline2007
- Author(s)
  N. Kusakabe, S. Ohtake, T. Yamaguchi, H. Habuchi, O. Habuchi
- Organizer
  Joint meeting of 80th Annual Scientific Meeting of the Japanese Biochemical Society and 30th Annual Meeting of the Molecular Biology Society ofJapan
- Place of Presentation
  Pacifico Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Presentation] コンドロイチン硫酸E合成に働くイカ硫酸転移酵素のクローニングと発現酵素の性質2006
- Author(s)
  山口照由、大竹しおり、羽渕脩躬
- Organizer
  第26回日本糖質学会年会
- Place of Presentation
  仙台国際センター
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570125
[Presentation] Molecular cloning of and expression of squid sulfotransferase involved in the synthesis of chondroitin sulfate E2006
- Author(s)
  T. Yamaguchi, S. Ohtake, O. Habuchi
- Organizer
  26th Annual Conference of The Japanese Society of Carbohydrate Research
- Place of Presentation
  Sendai International Center
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570125

1. HABUCHI Hiroko (90329821)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
2. MURAMATSU Takashi (00030891)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KIMATA Koji (10022641)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
4. 菅原一幸 (60154449)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 福田雅一 (70242899)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MURAMATSU Hisako (50182134)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAGAI Naoko (00367799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 鈴木明身 (70134533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 伊東信 (40253512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中田博 (90113141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 岩森正男 (90110022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 飯田静夫 (00009987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 松本勲武 (70012664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 西川義尚 (20109953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 牧田章 (60004561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 柳下正樹 (70132793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 齋藤政樹 (60012762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 田井直 (70112092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 三上雅久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 北川裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 渡辺秀人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

habuchi osami 羽渕 脩躬

羽渕 脩躬 ハブチ オサミ

HABUCHI Osami 羽渕 脩躬

羽淵 修躬 ハブチ オサミ

HABUSHI Osami 羽淵 脩躬

Research Projects

Research Products

Co-Researchers

炎症・疼痛制御における肥満細胞、マクロファージ高硫酸化プロテオグリカンの機能解明Principal InvestigatorOngoing

Principal Investigator

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Research Institution

Study on the physiological and pathological function of highly-sufated chondroitin/dermatan sulfatePrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Biosynthesis and biological roles of specific sulfation pattern of chondroitin sulfatePrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Spatio-temporal regulation of morphogenesis by heparan sulfate chains

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the function and control of sulfotransferases involving the synthesis of divergent structure of chondroitin sulfatePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the biological function of glycoconjugatesPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

糖鎖シグナルによる細胞間コミュニケーションの制御

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Purification and molecular cloning of chondroitin 4-sulfotransferasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional Analysis of chondroitin sulfate by knockout technique

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

グリコサミノグリカン合成に関与する硫酸転移酵素遺伝子の構造と機能Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

グリコサミノグリカン合成に関与する硫酸転移酵素遺伝子の構造と機能Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

糖鎖発現の制御因子

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Book] Chapter 44, Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15) in Handbook of Glycosyltransferases and Related Genes N. Taniguchi et al. (eds.),2014

Author(s)

Publisher

Data Source

habuchi osami 羽渕脩躬

羽渕脩躬ハブチオサミ

HABUCHI Osami 羽渕脩躬

羽淵修躬ハブチオサミ

HABUSHI Osami 羽淵脩躬

[Book] 第1章基礎編 3.糖鎖の細胞生物学 4)グリコサミノグリカンの硫酸化と疾患.遺伝子医学MOOK3 糖鎖と病気.2005