MIZOGUCHI Akira 溝口明

… Alternative Names

Researcher Number	90181916
Other IDs
External Links
Affiliation (Current)	2019 : 三重大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2015 – 2019 : 三重大学, 医学系研究科, 教授 2011 – 2016 : 三重大学, 医学(系)研究科(研究院), 教授 2013 – 2014 : 三重大学, 大学院医学系研究科, 教授 2007 – 2013 : Mie University, Graduate school of Medicine, Professor 2004 – 2008 : 三重大学, 医学部, 教授 … More
Review Section/Research Field	Principal Investigator Nerve anatomy/Neuropathology / General anatomy (including Histology/Embryology) / 神経解剖学 / Biological Sciences / Neurochemistry/Neuropharmacology / 分子細胞生物学 / General anatomy (including Histology/Embryology) / Science education Except Principal Investigator General anatomy (including Histology/Embryology) / Digestive surgery … More
Keywords	Principal Investigator 低分子量GTP結合蛋白質 / シナプス小胞 / シナプス / シナプス形成 / smg p25A / アクティブゾーン / Synapse formation / 2光子レーザー顕微鏡 / アクティブゾ-ン / Nectin … More Except Principal Investigator 神経再生 / 再生軸索 / 成長円錐 / 低分子量GTP結合蛋白質 / 基底膜 / 二光子レーザー顕微鏡 / Rab3A / GDP / smgp21 / bFGF / シュワン細胞 / シナプトフィジン / GTP結合蛋白質 / Cキナーゼ / シナプシンI / GDI / インテグリン / GAP / nerve regeneration / 移植 / イオンチャネル / ノックダウンマウス / カルシウム / synaptophysin / smgp25 / 神経科学 / シナプス小胞 / 肥満 / 脈絡叢 / 脊髄 / rasp21 / 遺伝子改変モデル動物 / PC13 / PC92 / アセチルコリン / protein kinase C / grafting / 小胞関連蛋白 / シンタキシン / 小胞膜関連蛋白質 / アディポカイン / 上衣細胞 / spinal cord / シナプトブレビン / 蛋白キナーゼC / てんかん / マクロファージ / アファディン / 胎児プログラミング / growth cone / シナプス / 接着因子 / 栄養因子 / トランスジェニックラット / 抗てんかん薬 / ras p21 / 中枢神経再生 / 末梢神経 / ネクチン / 異種細胞間接着 / 二光子励起顕微鏡 / cadherin / シナプトフィシン / Extracelluar matrix / graft / detergent treatment / カドヘリン / sprout / 外棍細胞 / 人工移植材料 / 2次元結晶 / Small GTP-Binding Protein / vesicle associated protein / Post capillary venule / 細胞接着・運動 / catonin / タイトジャンクション / GDP解離促進蛋白質 / Gタンパク質共役型受容体 / artificial tube / GTPase activating protein / 内視顕微鏡 / 神経突起 / 妊娠 / 免疫組織化学 / Rab3A p25 / イノシトールリン脂質代謝 / Choroid Plexus ependymal cell / detergent処理筋線維 / bFGF受容体(FGFR-1) / 消化管微小循環 / 構造生物学 / うさぎ坐骨神経 / GDP解離抑制蛋白質 / ワーラー変性 / 水チャネル / ニューロトロフィン / 細胞増殖因子 / 分子標的薬 / 末梢神経再生 / node of Ranvier / 機能性疾患 / 細胞膜受容体 / GTP exchange protein / Monoclonal antibody / 栄養因子受容体 / プロテインキナーゼC / 再生 / Rab3A P25 / ACL / モノクロ-ン抗体 / 軸索形質膜 / 情報伝達蛋白 / クロスト-ク / 子宮内環境 / 生活習慣病 / ラブフィリン / Aキナーゼ / 末梢循環障害 / エンド・エキソサイトーシス / アドヘレンスジャンクション / デスモソーム / differentiation / 細胞周期 / 小腸大腸肛門外科学 / 培養 / 細胞増殖 / 細胞間物質 / 高脂肪食 / GTPase活性化蛋白質 / rabbit sciatic nerve / PKC / アドへレンスジャンクション / カテニン / c-fos遺伝子 / アデイポカイン / 胎生期低栄養 / 神経シナプス / neurabin / GTP交換反応調節蛋白質 / 好中球 / 癌微小環境 / インスリン抵抗性 / Axon terminal / 癌転移 / ependymal cell / 筋基底膜 / amnion extracellular matrix / 微小循環不全 / 臓器特異的転移 / 潰瘍性大腸炎 / シナプス小胞膜蛋白質 / プレニル化 / Cキナ-ゼ / Outer core cell / detergent処理 / 大腸癌 / prenylation / 分化 / 生体内イメージング / 発がんプロモーター / 細胞外基質 / GTP Exchange Protein / 細胞情報伝達機構 / rab3A / 内棍細胞 / 糖代謝 / 生体内リアルタイムイメージング / coculture / ホスホタイロシン / 炎症反応 / 肺腺がん / 細胞外マトリックス / 免疫電顕 / regeneration / trophic factor / 脈絡叢上衣細胞 / 羊膜細胞外マトリックス / 神経伝達 / 脊髄移植 / regenerating axon / インスリン感受性 / 共焦点レーザー顕微鏡 / 酸化ストレス / ニューラビン / 腫瘍-宿主相互作用 / 上皮細胞 / 膜融合 / 軸索伸長 / Pacinian corpuscle / 病態 / 開口分泌 / 動脈硬化 / 共培養 / GTPase活性促進蛋白質 / axonal outgrowth / Inner core cell / シグナル伝達 / 脂肪組織の慢性炎症 / ネクチン様分子 / 癌臓器特異的転移 / プロテオミクス / small GTP-binding proteins / cーfos / 骨格節 / Prenylation / 脳・神経 / リアルタイムイメージング / 細胞接着 / 耐糖能異常 / ゲニラルゲラニル基 / 生体内イメージンング / signal transduction protein / 生体蛍光染色剤 / 細胞外物質 / 高血圧 / Schwann cell / 羊膜 / 血管平滑筋細胞 / シナプス形成 / 分子病態 / dorsal root ganglion neuron / 敗血症 / 細胞シグナル伝達機構 / synaptotagmin / シナプトタグミン / 成長心錐 / サイトカイン / 癌転移巣 / cーrafー1蛋白質 / L-lactic acid caprolactone / パチニ小体 / 糖代謝異常 / Rabphilin-3A / 壊死性腸炎 / peripheral nerve regeneration / Tumor markers / GTPase Activating Protein / smgp25A / 電子線結晶学 / ヒルシュスプルング病 / astrocyte / in vivo / 抗体医薬 / 炎症性腸疾患 / 人工チューブ / 遺伝子 / 腫瘍マ-カ- / 糖脂質代謝 / 後根神経節ニューロン / 脈略叢上衣細胞 / 再生芽 / 前シナプス / 成人病 / ゲラニルゲラニル基 / レーザー内視顕微鏡 / アストロサイト / adhension molecule / choroid plexus / <ras>___ー p21 / 可食性色素 / プロティンキナーゼC / Intracellular Messenger Systems / ネクチン様分子-5 / Hirschsprung病 / DSS腸炎マウス / N-カドヘリン / 樹状突起 / muscle basal lamina / 生理学 / ランヴィエ絞輪 / 発生・分化 / 前頭葉 / 軸索終未 / 軸索終末 / 小脳 Less

ヒルシュスプルング病における腸管壁内神経節細胞局在の二光子レーザー顕微鏡観察研究Ongoing
- Principal Investigator
  
  内田恵一
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Mie University
Dynamic regulation of cerebellar neural circuits by "scrap and build" mechanismsOngoing
- Principal Investigator
  
  柚崎通介
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
生体蛍光染色剤とレーザー内視顕微鏡によるリアルタイム光学的組織診断法の開発Ongoing
- Principal Investigator
  
  田中光司
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Mie University
Roles and modes of action of nectins in heterotypic cell-cell adhesions
- Principal Investigator
  
  Takai Yoshimi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kobe University
In vivo imaging system of dynamics of molecularly targeted drugs on the metastatic tumor xenografts using a multiphoton microscopy
- Principal Investigator
  
  TANAKA KOJI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Mie University
Intravital imaging of microcirculation on murine sepsis model using two-photon laser scanning microscopy
- Principal Investigator
  
  KOBAYASHI MINAKO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Mie University
Netsの概念に基づく２光子レーザー顕微鏡を用いた壊死性腸炎の病態解明と治療戦略
- Principal Investigator
  
  小池勇樹
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Mie University
Development of education movies demonstrating real-time biophysical phenomena by two photon laser microscopyPrincipal Investigator
- Principal Investigator
  
  MIZOGUCHI Akira
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Science education
- Research Institution
  Mie University
In vivo real-time visualization of in inflammatory bowel disease model mice using two photon laser scanning microscopy
- Principal Investigator
  
  UCHIDA Keiichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Mie University
Morphological analysis of the mechanisms of organ-specific metastasis using intravital multiphoton microscopy
- Principal Investigator
  
  MORIMOTO Yuhki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Mie University
Exploring the development of functional disorders in central nervous system
- Principal Investigator
  
  OKADA Motohiro
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Mie University
Roles of Cell Adhesion and Signaling in Cell Morphogenesis
- Principal Investigator
  
  TAKAI YOSHIMI
- Project Period (FY)
  2009 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kobe University
Comprehensive Study on Experimental Proof of Fetal Origins of Adult Diseases Hypothesis and its Clinical Application
- Principal Investigator
  
  SAGAWA Norimasa
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Mie University
中枢神経系機能性疾患発症前治療介入の有効性検証
- Principal Investigator
  
  OKADA Motohiro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Mie University
Investigation on the mechanism of adult diseases originated fromimpaired intrauterine milieu and development of prevention of the diseases
- Principal Investigator
  
  SAGAWA Norimasa
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Mie University
Histological analysis of brain injury with two-photon microscopyPrincipal Investigator
- Principal Investigator
  
  MIZOGUCHI Akira
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Mie University
Structural study of signal transduction through membrane proteins, channels and receptors
- Principal Investigator
  
  FUJIYOSHI Yoshinori
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
細胞接着分子によるグリア細胞・神経細胞組織形成の制御機構Principal Investigator
- Principal Investigator
  
  溝口明
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Mie University
A control structure of a nervous system synapse morphosis by a cell adhesion molecule.Principal Investigator
- Principal Investigator
  
  MIZOGUCHI Akira
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Mie University
Facilitation of central nerve regeneration by choroid plexus ependymal cells
- Principal Investigator
  
  IDE Chizuka
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  KYOTO UNIVERSITY
Nectin : An Adhesion Molecule Involved in Formation-of SynapsPrincipal Investigator
- Principal Investigator
  
  MIZOGUCHI Akira
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Mie University
  Kyoto University
Development of artificial tubes to be used for repairing a large peripheral nerve gap
- Principal Investigator
  
  IDE Chizuka
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  広領域
- Research Institution
  KYOTO UNIVERSITY
中枢神経再生のための新しい細胞移植の試み
- Principal Investigator
  
  井出千束
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto University
Study on the condition for central nerve regeneration-grafting of ependymal cells and cell proliferation by neuregulin-
- Principal Investigator
  
  IDE Chizuka
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kyoto University
シュワン細胞の発現する神経細胞生存維持・軸索促進因子の解析‐神経再生における神経栄養因子、細胞接着因子を中心として‐
- Principal Investigator
  
  井出千束
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Axon-Schwann cell relationship in nerve regeneration and the mechanisms for the promotion of nerve
- Principal Investigator
  
  IDE Chizuka
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  KYOTO UNIVERSITY
抹消神経再生軸索におけるbFGF受容体の機能発現に関する免疫組織化学的研究
- Principal Investigator
  
  藤本悦子
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kobe University
Analysis on the developmental changes in molecular architecture of active zonesPrincipal Investigator
- Principal Investigator
  
  MIZOGUCHI Akira
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  KYOTO UNIVERSITY
膜蛋白質の差異に基づく小胞膜系の機能的多様性の解析-シナプスと再生軸索成長円錐において-
- Principal Investigator
  
  井出千束
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
定量的免疫電顕法を用いたシナプス小胞の前シナプス形質膜への開口分泌機構の解析-低分子量GTP結合蛋白質の作用機構を中心として-Principal Investigator
- Principal Investigator
  
  溝口明
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kobe University
Expression of vesicle-associated proteins during the course of differentiation of growth cones into synaptic terminals in nerve regeneration (synaptophysin, synaptotagmin, protein kinase C,etc)
- Principal Investigator
  
  IDE Chizuka
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  KYOTO UNIVERSITY
再生軸索成長円錐から神経筋接合部への連続的機能分化に伴う小胞膜融合機構の変化の解析
- Principal Investigator
  
  井出千束
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
成長円錐における小胞の選別輸送と表面膜への融合機構の解析
- Principal Investigator
  
  井出千束
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
低分子量GTP結合蛋白質とその調節蛋白質のシナプスにおける機能と作用点Principal Investigator
- Principal Investigator
  
  溝口明
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  分子細胞生物学
- Research Institution
  Kobe University
Mechanisms of regenerating spout formation and growth in the peripheral nerves as studied by confocal laser scanning and immunoelectron microscopy
- Principal Investigator
  
  IDE Chizuka
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kobe University
トランスミッタ-放出過程に於る低分子量GTP結合蛋白質の急速凍結法による機能解析Principal Investigator
- Principal Investigator
  
  溝口明
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
運動神経のシナプス小胞における低分子量GTP結合蛋白質smg p25Aの役割Principal Investigator
- Principal Investigator
  
  溝口明
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  神経解剖学
- Research Institution
  Kobe University
細胞増殖シグナル伝達の機構と癌遺伝子産物の作用
- Principal Investigator
  
  TAKAI YOSHIMI
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kobe University
細胞分化の制御におけるCキナ-ゼとrasp21類似GTP結合蛋白質の作用機構
- Principal Investigator
  
  高井義美
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
The role of extracellular matrix in growth and differentiation of regenerating axons : histochemical examination using monoclonal antibodies
- Principal Investigator
  
  IDE Chizuka
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kobe University
  Iwate Medical University
Small GTP-Binding Proteins and Intracellular Messenger Systems
- Principal Investigator
  
  TAKAI Yoshimi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  代謝生物化学
- Research Institution
  Kobe University
cDNAs and Antibodies for Small GTP-binding Proteins
- Principal Investigator
  
  TAKAI Yoshimi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B).
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
血管平滑筋細胞の細胞膜受容伝達機構を構成する蛋白質の同定とその機能の解析
- Principal Investigator
  
  高井義美
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kobe University

All 2017 2016 2015 2014 2013 2012 2011 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] Multiple roles of afadin in the ultrastructural morphogenesis of mouse hippocampal mossy fiber synapses.2017
- Author(s)
  Sai, K., Wang, S., Kaito, A., Fujiwara, T., Maruo, T., Itoh, Y., Miyata, M., Sakakibara, S., Miyazaki, N., Murata, K., Yamaguchi, Y., Haruta, T., Nishioka, H., Motojima, Y., Komura, M., Kimura, K., Mandai, K., Takai, Y., and Mizoguchi, A.
- Journal Title
  
  J Comp Neurol
  
  Volume : 印刷中
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26251013
[Journal Article] Roles of afadin in the formation of the cellular architecture of the mouse hippocampus and dentate gyrus.2017
- Author(s)
  Miyata M, Maruo T, Kaito A, Wang S, Yamamoto H, Fujiwara T, Mizoguchi A, Mandai K, Takai Y
- Journal Title
  
  Molecular and Cellular Neuroscience
  
  Volume : 79 Pages : 34-44
- DOI
  10.1016/j.mcn.2016.12.007
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06463, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-16K19036
[Journal Article] Localization of nectin-2delta at perivascular astrocytic endfoot processes and degeneration of astrocytes and neurons in nectin-2 knockout mouse brain.2016
- Author(s)
  Miyata M, Mandai K, Maruo T, Sato J, Shiotani H, Kaito A, Itoh Y, Wang S, Fujiwara T, Mizoguchi A, Takai Y, Rikitake Y
- Journal Title
  
  Brain Research
  
  Volume : 1649 Pages : 90-101
- DOI
  10.1016/j.brainres.2016.08.023
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06463, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-16K19036
[Journal Article] Regulatory role of the cell adhesion molecule nectin-1 in GABAergic inhibitory synaptic transmission in the CA3 region of mouse hippocampus.2016
- Author(s)
  Geng, X., Mandai, K., Maruo, T., Wang, S., Fujiwara, T., Mizoguchi, A., Takai, Y., and Mori, M.
- Journal Title
  
  Genes Cells
  
  Volume : 21 Pages : 88-98
- DOI
  10.1111/gtc.12322
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26251013
[Journal Article] In vivo optical pathology of paclitaxel efficacy on the peritoneal metastatic xenograft model of gastric cancer using two-photon laser scanning microscopy2015
- Author(s)
  Shimura T, Tanaka K, Toiyama Y, Okigami M, Ide S, Kitajima T, Kondo S, Saigusa S, Ohi M, Araki T, Inoue Y, Uchida K, Mohri Y, Mizoguchi A, Kusunoki M.
- Journal Title
  
  Gastric Cancer
  
  Volume : 18 Pages : 109-118
- DOI
  10.1007/s10120-013-0334-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462052, KAKENHI-PROJECT-23300284
[Journal Article] Nectin-1 spots as a novel adhesion apparatus that tethers mitral cell lateral dendrites in a dendritic meshwork structure of the developing mouse olfactory bulb.2015
- Author(s)
  Inoue T, Fujiwara T, Rikitake Y, Maruo T, Mandai K, Kimura K, Kayahara T, Wang S, Ioth Y, Sai K, Mori M, Mori K, Mizoguchi A, Takai Y.
- Journal Title
  
  J Comp Neurol.
  
  Volume : 印刷中
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26251013
[Journal Article] Dynamic pathology for leukocyte-platelet formation in sepsis model.2015
- Author(s)
  Koike Y, Tanaka K, Kobayashi M, Toiyama Y, Inoue Y, Mohri Y, Uchida K, Mizoguchi A, Kusunoki M.
- Journal Title
  
  J Surg Res.
  
  Volume : 195 Pages : 188-195
- DOI
  10.1016/j.jss.2014.05.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462053
[Journal Article] Visualization of in vivo thromboprophylactic and thrombolytic efficacy of enoxaparin in laser-induced vascular endothelial injury model using multiphoton microscopy.2015
- Author(s)
  Tanaka K, Koike Y, Matsushita K, Okigami M, Toiyama Y, Kawamura M, Saigusa S, Okugawa Y, Inoue Y, Uchida K, Araki T, Mohri Y, Mizoguchi A, Kusunoki M.
- Journal Title
  
  Am J Transl Res.
  
  Volume : ７ Pages : 79-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462052
[Journal Article] Nectin-1 spots as a novel adhesion apparatus that tethers mitral cell lateral dendrites in a dendritic meshwork structure of the developing mouse olfactory bulb.2015
- Author(s)
  Inoue, T., Fujiwara, T., Rikitake, Y., Maruo, T., Mandai, K., Kimura, K, Kayahara, T, Wang, S., Itoh, Y., Sai, K., Mori, M., Mori, K., Mizoguchi, A., and Takai, Y.
- Journal Title
  
  J Comp Neurol
  
  Volume : 523 Pages : 1824-1839
- DOI
  10.1002/cne.23762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26251013
[Journal Article] Nectin-1 spots as a novel adhesion apparatus that tethers mitral cell lateral dendrites in a dendritic meshwork structure of the developing mouse olfactory bulb.2015
- Author(s)
  Inoue T, Fujiwara T, Rikitake Y, Maruo T, Mandai K, Kimura K, Kayahara T, Wang S, Ioth Y, Sai K, Mori M, Mori K, Mizoguchi A, Takai Y.
- Journal Title
  
  J Comp Neurol.
  
  Volume : 印刷中
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21227005
[Journal Article] Nectin-1 spots regulate the branching of olfactory mitral cell dendrites.2015
- Author(s)
  Fujiwara, T., Inoue, T., Maruo, T., Rikitake, Y., Ieki, N., Mandai, K., Kimura, K., Kayahara, T., Wang, S., Itoh, Y., Sai, K., Mori, M., Mori, K., Takai, Y., and Mizoguchi, A.
- Journal Title
  
  Mol Cell Neurosci
  
  Volume : 68 Pages : 143-150
- DOI
  10.1016/j.mcn.2015.07.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26251013
[Journal Article] In vivo optical pathology of paclitaxel efficacy on the peritoneal metastatic xenograft model of gastric cancer using two-photon laser scanning microscopy.2014
- Author(s)
  Shimura T, Tanaka K, Toiyama Y, Okigami M, Ide S, Kitajima T, Kondo S, Saigusa S, Ohi M, Araki T, Inoue Y, Uchida K, Mohri Y, Mizoguchi A, Kusunoki M.
- Journal Title
  
  Gastric Cancer.
  
  Volume : Jan 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462052
[Journal Article] Sevoflurane in combination with propofol, not thiopental, induces a more robust neuroapoptosis than sevoflurane alone in the neonatal mouse brain.2014
- Author(s)
  Tagawa T, Sakuraba S, Kimura K, Mizoguchi A
- Journal Title
  
  Journal of Anesthesia
  
  Volume : (in press) Pages : 815-820
- DOI
  10.1007/s00540-014-1822-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300284, KAKENHI-PROJECT-25640022, KAKENHI-PROJECT-25861372
[Journal Article] Aberrant cochlear hair cell attachments owing to nectin-3 deficiency cause hair　bundle abnormalities2014
- Author(s)
  Fukuda T, Kominami K, Wang S, Togashi H, Hirata K, Mizoguchi A, Rikitake Y, Takai Y.
- Journal Title
  
  Development
  
  Volume : 141 Pages : 399-409
- DOI
  10.1242/dev.094995
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-23300284, KAKENHI-PUBLICLY-25111716, KAKENHI-PUBLICLY-25127710, KAKENHI-PROJECT-25440107, KAKENHI-PROJECT-26400205
[Journal Article] Genetic ablation of afadin causes mislocalization and deformation of Paneth cells in the mouse small intestinal epithelium2014
- Author(s)
  Tanaka-Okamoto M, Itoh Y, Miyoshi J, Mizoguchi A, Mizutani K, Takai Y, Inoue M.
- Journal Title
  
  PLoS One
  
  Volume : 9
- DOI
  10.1371/journal.pone.0110549
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-24790284, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-26860190
[Journal Article] Intravital imaging of gastrointestinal diseases in preclinical models using two-photon laser scanning microscopy2013
- Author(s)
  Tanaka K, Toiyama Y, Inoue Y, Uchida K, Araki T, Mohri Y, Mizoguchi A, Kusunoki M
- Journal Title
  
  Surg Today
  
  Volume : 43 Pages : 123-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659646
[Journal Article] Intravital imaging of gastrointestinal diseases in preclinical models using two-photon laser scanning microscopy2013
- Author(s)
  Tanaka K, Toiyama Y, Inoue Y, Uchida K, Araki T, Mohri Y, Mizoguchi A, Kusunoki M.
- Journal Title
  
  Surg Today
  
  Volume : 43 Pages : 123-129
- DOI
  10.1007/s00595-012-0283-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390377, KAKENHI-PROJECT-23300284, KAKENHI-PROJECT-23591958, KAKENHI-PROJECT-23659646, KAKENHI-PROJECT-24659588
[Journal Article] In vivo real-time imaging of chemotherapy response on the liver metastatic tumor microenvironment using multiphoton microscopy2012
- Author(s)
  Tanaka K et al.
- Journal Title
  
  Oncol Rep
  
  Volume : 28 Pages : 1822-1830
- DOI
  10.3892/or.2012.1983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390377, KAKENHI-PROJECT-23300284, KAKENHI-PROJECT-23591958, KAKENHI-PROJECT-23659646
[Journal Article] Intravital dual-colored visualization of colorectal liver metastasis in living mice using two photon laser scanning microscopy2012
- Author(s)
  Tanaka K, Morimoto Y, Toiyama Y, Okugawa Y, Inoue Y, Uchida K, Kimura K, Mizoguchi A, Kusunoki M
- Journal Title
  
  Microsc Res Tech
  
  Volume : 75 Pages : 307-315
- Data Source
  KAKENHI-PROJECT-23591958
[Journal Article] Periderm cells covering palatal shelves have tight junctions and their desquamation reduces the polarity of palatal shelf epithelial cells in palatogenesis2012
- Author(s)
  Yoshida, M.
- Journal Title
  
  Genes Cells
  
  Volume : 17 Pages : 455-472
- DOI
  10.1111/j.1365-2443.2012.01601.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-22792047, KAKENHI-PROJECT-23300284
[Journal Article] Intravital dual-colored visualization of colorectal liver metastasis in living mice using two photon laser scanning microscopy2012
- Author(s)
  Tanaka K, Morimoto Y, Toiyama Y, Okugawa Y, Inoue Y, Uchida K, Kimura K, Mizoguchi A, Kusunoki M
- Journal Title
  
  Microsc Res Tech
  
  Volume : 75 Pages : 307-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659646
[Journal Article] In vivo time-course imaging of tumor angiogenesis in colorectal liver metastases in the same living mice using two-photon laser scanning microscopy.2012
- Author(s)
  Tanaka K, Morimoto Y, Toiyama Y, Matsushita K, Kawamura M, Koike Y, Okugawa Y, Inoue Y, Uchida K, Araki T, Mizoguchi A, Kusunoki M
- Journal Title
  
  J Oncol.
  
  Volume : 2012 Pages : 2012-2018
- DOI
  10.1155/2012/265487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300284, KAKENHI-PROJECT-23792027
[Journal Article] In vivo real-time imaging of chemotherapy response on the liver metastatic tumor microenvironment using multiphoton microscopy2012
- Author(s)
  Tanaka K, Okigami M, Toiyama Y, Morimoto Y, Matsushita K, Kawamura M, Hashimoto K, Saigusa S, Okugawa Y, Inoue Y, Uchida K, Araki T, Mohri Y,Mizoguchi A, Kusunoki M
- Journal Title
  
  Oncol Rep
  
  Volume : 28 Pages : 1822-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659646
[Journal Article] Distinct Distribution and Localization of Rho-kinase in Mouse Epithelial, Muscle and Neural Tissues2012
- Author(s)
  Iizuka, M.
- Journal Title
  
  Cell Structure and Function
  
  Volume : 37 Issue : 2 Pages : 155-175
- DOI
  10.1247/csf.12018
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227006, KAKENHI-PROJECT-23300284
[Journal Article] Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration2012
- Author(s)
  Wang, Shujie, et al.
- Journal Title
  
  Journal of cell biology
  
  Volume : 199 Pages : 331-345
- DOI
  10.1083/jcb.201202041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J07129, KAKENHI-PROJECT-20227006, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23300284, KAKENHI-PROJECT-23790247, KAKENHI-PROJECT-24591416, KAKENHI-PUBLICLY-23123507
[Journal Article] In vivo time-course imaging of tumor angiogenesis in colorectal liver metastases in the same living mice using two-photon laser scanning microscopy2012
- Author(s)
  Tanaka K, Morimoto Y, Toiyama Y, Matsushita K, Kawamura M, Koike Y, Okugawa Y, Inoue Y, Uchida K, Araki T, Mizoguchi A, Kusunoki M
- Journal Title
  
  J Oncol
  
  Volume : 2012 Pages : 265487-265487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659646
[Journal Article] Intravital dual-colored visualization of colorectal liver metastasis in living mice using two photon laser scanning microscopy2012
- Author(s)
  Tanaka K, Morimoto Y, Toiyama Y, Okugawa Y, Inoue Y, Uchida K, Kimura K, Mizoguchi A, Kusunoki M
- Journal Title
  
  Microsc Res Tech
  
  Volume : 75(3) Pages : 307-315
- DOI
  10.1002/jemt.21059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300284
[Journal Article] Behavioral alterations associated with targeted disruption of exons 2 and 3 of the DISC1 gene in the mouse.2011
- Author(s)
  K Kuroda, S Yamada, M Tanaka, M Iizuka, H Yano, D Mori, D Tsuboi, T Nishioka, T Namba, Y Iizuka, S Kubota, T Nagai, D Ibi, R Wang, A Enomoto, M Isotani-Sakakibara, N Asai, K Kimura, H Kiyonari, T Abe, A Mizoguchi,M Sokabe, M Takahashi, K Yamada, K Kaibuchi
- Journal Title
  
  Hum. Mol. Genet.
  
  Volume : 20 Pages : 4666-4683
- DOI
  10.1093/hmg/ddr400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03454, KAKENHI-PUBLICLY-23110506, KAKENHI-PROJECT-23300284, KAKENHI-PROJECT-23700443, KAKENHI-PROJECT-23790291
[Journal Article] In vivo real-time two-photon microscopic imaging of platelet aggregation induced by selective laser irradiation to the endothelium created in the beta-actin-green fluorescent protein transgenic mice.2011
- Author(s)
  Koike Y, Tanaka K, Okugawa Y, Morimoto Y, Toiyama Y, Uchida K, Miki C, Mizoguchi A, Kusunoki M
- Journal Title
  
  J Thromb Thrombolysis
  
  Volume : 32(2) Pages : 138-145
- DOI
  10.1007/s11239-011-0600-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300284, KAKENHI-PROJECT-23792027
[Journal Article] Intravital three-dimensional dynamic pathology of experimental colitis in living mice using two-photon laser scanning microscopy2011
- Author(s)
  Morimoto Y, Tanaka K, Toiyama Y, Inoue Y, Araki T, Uchida K, Kimura K, Mizoguchi A, Kusunoki M
- Journal Title
  
  J Gastrointest Surg
  
  Volume : 15 Pages : 1842-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659646
[Journal Article] Intravital Three-Dimensional Dynamic Pathology of Experimental Colitis in Living Mice Using Two-Photon Laser Scanning Microscopy2011
- Author(s)
  Morimoto Y, Tanaka K, Toiyama Y, Inoue Y, Araki T, Uchida K, Kimura K, Mizoguchi A, Kusunoki M
- Journal Title
  
  J Gastrointest Surg
  
  Volume : 15(10) Pages : 1842-1850
- DOI
  10.1007/s11605-011-1632-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300284
[Journal Article] Intravital three-dimensional dynamic pathology of experimental colitis in living mice using two-photon laser scanning microscopy.2011
- Author(s)
  Morimoto Y, Tanaka K, Toiyama Y, Inoue Y, Araki T, Uchida K, Kimura K, Mizoguchi A, Kusunoki M.
- Journal Title
  
  J Gastrointest Surg.
  
  Volume : 15 Pages : 1842-1850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659646
[Journal Article] In vivo real-time two-photon microscopic imaging of platelet aggregation induced by selective laser irradiation to the endothelium created in the beta-actin-green fluorescent protein transgenic mice2011
- Author(s)
  Koike Y, Tanaka K, Okugawa Y, Morimoto Y, Toiyama Y, Uchida K, Miki C, Mizoguchi A, Kusunoki M
- Journal Title
  
  J Thromb Thrombolysis
  
  Volume : 32 Pages : 138-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659646
[Journal Article] Establishment of cell polarity by afadin during the for mation of embryoid bodies.2008
- Author(s)
  Komura H, Ogita H, Ikeda W, Mizoguchi A, Miyoshi J, Takai Y.
- Journal Title
  
  Genes Cells. 13
  
  Pages : 79-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300121
[Journal Article] A nuclearfactor-kappaB inhibitor pyrrolidined ithiocarbamateameliorates pulmonary hypertension in rats.2007
- Author(s)
  Sawada H, Mitani Y, Maruyama J, Jiang BH, Ikeyama Y, Dida FA, Yamamoto H, Imanaka Yoshida K, Shimpo H, Mizoguchi A, Maruyama K, Komada Y.
- Journal Title
  
  Chest. 132
  
  Pages : 1265-1274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300121
[Journal Article] Diminished climbing fiber innervation of Purkinjec ells in thecerebellum of myosin Va mutant mice and rats.2007
- Author(s)
  Takagishi Y, Hashimoto K, Kayahara T, Watanabe M, Otsuka H, Mizoguchi A, Kano M, Murata Y.
- Journal Title
  
  Dev Neurobiol. 67
  
  Pages : 909-923
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300121
[Journal Article] Impaired cerebellar development and function in mice lacking CAPS2, a protein involved in meurotrophin release2007
- Author(s)
  Sadakata T, Kakegawa W, Mizoguchi A, Washida M, Katoh-Semba R, Shutoh F, Okamoto T, Nakashima H, Kimura K, Tanaka M, Sekine Y, Itohara S, Yuzaki M, Nagao S. Fururchi T.
- Journal Title
  
  J Neurosci. 27
  
  Pages : 2472-2482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300121
[Journal Article] Activity-induced protocadherin arcadlin regulates dendriticspine number by triggering N-cadherin endocytosis viaTAO2beta and p38 MAP kinases.2007
- Author(s)
  Yasuda S, Tanaka H, Sugiura H, Okamura K, Sakaguchi T, Tran U, Takemiya T, Mizoguchi A, Yagita Y, Sakurai T, DeRobertis EM, Yamagata K.
- Journal Title
  
  Neuron. 56
  
  Pages : 456-471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300121
[Journal Article] Complementation of placental defects and embryonic lethality by trophoblast-specific lentiviral gene transfer.2007
- Author(s)
  Okada Y, Ueshin Y, Isotani A, Saito-Fujita T, Nakashima H, Kimura K, Mizoguchi A, Oh-Hora M, Mori Y, Ogata M, Oshima RG, Okabe M, Ikawa M
- Journal Title
  
  Nat Biotechnol.
- Data Source
  KAKENHI-PROJECT-18300121
[Journal Article] Synaptic scaffolding molecule alphaf is a scaffold to mediate N-methyl-D-aspartate receptor-dependent RhoA actication in dendrites.2007
- Author(s)
  lisa J, lshizaki H, Okamoto-Tanaka M, Kawata A, Sumita K, Ohgake S, Sato Y, Yorifuji H, Nukina N, Ohashi K, Mizuno K, Tautsumi T, Mizoguchi A, Miyoshi J, Takai Y, Hata Y.
- Journal Title
  
  Mol Cell Biol. 27
  
  Pages : 4388-4405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300121
[Journal Article] Characterization and function of MYPT2, a target subunit of myosin phosphatase in heart.2006
- Author(s)
  Okamoto R, Kato T, Mizoguchi A, Takahashi N, Nakakuki T, Mizutani H, Isaka N, Imanaka-Yoshida K, Kaibuchi K, Lu Z, Mabuchi K, Tao T, Hartshorne DJ, Nakano T, Ito M.
- Journal Title
  
  Cell Signal. In press
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Implications of the Aquaporin-4 Structure on Array Formation and Cell Adhesion.2006
- Author(s)
  Hiroaki Y, Tani K, Kamegawa A, Gyobu N, Nishikawa K, Suzuki H, Walz T, Sasaki S, Mitsuoka K, Kimura K, Mizoguchi A, Fujiyoshi Y.
- Journal Title
  
  J Mol Biol. 355・4
  
  Pages : 628-639
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Involvement of nectins in the formation of puncta adherentia junctions and the mossy fiber trajectory in the mouse hippocampus.2006
- Author(s)
  Honda T, Sakisaka T, Yamada T, Kumazawa N, Hoshino T, Kajita M, Kayahara T, Ishizaki H, Tanaka-Okamoto M, Mizoguchi A, Manabe T, Miyoshi J, Takai Y.
- Journal Title
  
  Mol Cell Neurosci. 31-2
  
  Pages : 315-325
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Differential localization and regulation of stargazin-like protein, gamma-8 and stargazin in the plasma membrane of hippoca mpal and cortical neurons.2006
- Author(s)
  Inamura M, Itakura M, Okamoto H, Hoka S, Mizoguchi A, Fukazawa Y, Shigemoto R, Yamamori S, Takahashi M.
- Journal Title
  
  Neurosci Res. (In press)
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Choroid plexus ependymal cells host neural progenitor cells in the rat.2006
- Author(s)
  Itokazu Y, Kitada M, Dezawa M, Mizoguchi A, Matsumoto N, Shimizu A, Ide C.
- Journal Title
  
  Glia. 53-1
  
  Pages : 32-42
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Involvement of nectins in the formation of puncta adherentia junctions and the mossy fiber trajectory in the mouse hippocampus.2006
- Author(s)
  IHonda T, Sakisaka T, Yamada T, Kumazawa N, Hoshino T, Kajita M, Kayahara T, Ishizaki H, Tanaka-Okamoto M, Mizoguchi A, Manabe T, Miyoshi J, Takai Y.
- Journal Title
  
  Mol Cell Neurosci. 31・2
  
  Pages : 315-325
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] RGS2 promotes formation of neurites by stimulating microtubule polymerization.2006
- Author(s)
  Heo K, Ha SH, Chae YC, Lee S, Oh YS, Kim YH, Kim SH, Kim JH, Mizoguchi A, Itoh TJ, Kwon HM, Ryu SH, Suh PG
- Journal Title
  
  Cell Signal. 18・12
  
  Pages : 2182-2192
- Data Source
  KAKENHI-PROJECT-18300121
[Journal Article] Implications of the Aquaporin-4 Structure on Array Formation and Cell Adhesion.2006
- Author(s)
  Y. Hiroaki, K. Tani, A. Kamegawa, N. Gyobu, K. Nishikawa, H. Suzuki, T. Walz, S. Sasaki, K. Mitsuoka, K. Kimura, A. Mizoguchi and Y. Fujiyoshi
- Journal Title
  
  J. Mol. Biol. 355
  
  Pages : 628-639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16001005
[Journal Article] Choroid plexus ependymal cells host neural progenitor cells in the rat.2006
- Author(s)
  Itokazu Y, Kitada M, Dezawa M, Mizoguchi A, Matsumoto N, Shimazu A, Ide C.
- Journal Title
  
  Glia. 53・1
  
  Pages : 32-42
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Characterization and function of MYPT2, a target subunit of myosin phosphatase in heart.2006
- Author(s)
  Okamoto R, Kato T, Mizoguchi A, Takahashi N, Nakakuki T, Mizutani H, Isaka N, Imanaka-Yoshida K, Kaibuchi K, Lu Z, Mabuchi K, Tao T, Hartshorne DJ, Nakano T, Ito M.
- Journal Title
  
  Cell Signal. (In press)
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Characterization and function of MYPT2, a target subunit of myosin phosphatase in heart.2006
- Author(s)
  Okamoto R, Kato T, Mizoguchi A, Takahashi N, Nakakuki T, Mizutani H, Isaka N, Imanaka-Yoshida K, Kaibuchi K, Lu Z, Mabuchi K, Tao T, Hartshorne DJ, Nakano T, Ito M
- Journal Title
  
  Cell Signal. 18・9
  
  Pages : 1408-1416
- Data Source
  KAKENHI-PROJECT-18300121
[Journal Article] Implications of the Aquaporin-4 Structure on Array Formation and Cell Adhesion.2006
- Author(s)
  Hiroaki Y, Tani K, Kamegawa A, Gyobu N, Nishikawa K, Suzuki H, Walz T, Sasaki S, Mitsuoka K, Kimura K, MIzoguchi A, Fujiyoshi Y.
- Journal Title
  
  J Mol Biol. 355・4
  
  Pages : 628-639
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Choroid plexus ependymal cells host neural progenitor cells in the rat.2006
- Author(s)
  Itokazu Y, Kitada M, Dezawa M, Mizoguchi A, Matsumoto N, Shimizu A, Ide C
- Journal Title
  
  Glia 53・1
  
  Pages : 32-42
- Data Source
  KAKENHI-PROJECT-18300121
[Journal Article] Involvement of nectins in the formation of puncta adherentia junctions and the mossy fiber trajectory in the mouse hippocampus.2006
- Author(s)
  Honda T, Sakisaka T, Yamada T, Kumazawa N, Hoshino T, Kajita M, Kayahara T, Ishizaki H, Tanaka-Okamoto M, Mizoguchi A, Manabe T, Miyoshi J, Takai Y
- Journal Title
  
  Mol Cell Neurosci. 31・2
  
  Pages : 315-325
- Data Source
  KAKENHI-PROJECT-18300121
[Journal Article] Implications of the Aquaporin-4 Structure on Array Formation and Cell Adhesion.2006
- Author(s)
  Hiroaki Y, Tani K, Kamegawa A, Gyobu N, Nishikawa K, Suzuki H, Walz T, Sasaki S, Mitsuoka K, Kimura K, Mizoguchi A, Fujiyoshi Y
- Journal Title
  
  J Mol Biol. 355・4
  
  Pages : 628-639
- Data Source
  KAKENHI-PROJECT-18300121
[Journal Article] Differential localization and regulation of stargazin-like protein, gemma-8 and stargazin in the plasma membrane of hippocampal and cortical neurons.2006
- Author(s)
  Inamura M, Itakura M, Okamuto H, Hoka S, Mizoguchi A, Fukazawa Y, Shigemoto R, Yamamori S, Takahashi M.
- Journal Title
  
  Neurosci Res. 55-1
  
  Pages : 45-53
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Characterizationg and function of MYPT2, a target subunit of myosin phosphatase in heart.2006
- Author(s)
  Okamoto R, Kato T, Mizoguchi A, Takahashi N, Nakakuki T, Mizutani H, Isaka N, Imanaka-Yoshida K, Kaibuchi K, Lu Z, Mabuchi K, Tao T, Hartshorne DJ, Nakano T, Ito M.
- Journal Title
  
  Cell Signal. (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Choroid plexus ependymal cells host neural progenitor cells in the rat.2006
- Author(s)
  Itokazu Y, Kitada M, Dezawa M, Mizoguchi A, Matsumoto N, Shimizu A, Ide C.
- Journal Title
  
  Glia. 53・1
  
  Pages : 32-42
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Differential localization and regulation of stargazin-like protein, gamma-8 and stargazin in the plasma membrane of hippocampal and cortical neurons.2006
- Author(s)
  Inamura M, Itakura M, Okamoto H, Hoka S, Mizoguchi A, Fukazawa Y, Shigemoto R, Yamamori S, Takahashi M
- Journal Title
  
  Neurosci Res. 55・1
  
  Pages : 45-53
- Data Source
  KAKENHI-PROJECT-18300121
[Journal Article] Protruding disordered loop of gC1qR is specifically exposed and related to antiapoptotic property in germ cell lineage.2006
- Author(s)
  Kitazawa S, Takenaka A, Kondo T, Mizoguchi A, Kitazawa R
- Journal Title
  
  Histochem Cell Biol. 126・6
  
  Pages : 655-677
- Data Source
  KAKENHI-PROJECT-18300121
[Journal Article] Differential localization and regulation of stargazin-like protein, gamma-8 and stargazin in the plasma membrane of hippocampal and cortical neurons.2006
- Author(s)
  Inamura M, Itakura M, Okamoto H, Hoka S, Mizoguchi A, Fukazawa Y, Shigemoto R, Yamamori S, Takahashi M.
- Journal Title
  
  Neurosci Res. 55-1
  
  Pages : 45-53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Implications of the Aquaporin-4 Structure on Array Formation and Cell Adhesion.2006
- Author(s)
  Hiroaki Y, Tani K, Kamegawa A, Gyobu N, Nishikawa K, Suzuki H, Walz T, Sasaki S, Mitsuoka K, Kimura K, Mizoguchi A, Fujiyoshi Y.
- Journal Title
  
  J Mol Biol. 355-4
  
  Pages : 628-639
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Persistence of gene expression changes in noninflamed and inflamed colonic mucosa in ulcerative colitis and their presence in colonic carcinoma.2005
- Author(s)
  Toiyama Y, Mizoguchi A, Kimura K, Araki T, Yoshiyama S, Sakaguchi K, Miki C, Kusunoki M
- Journal Title
  
  World J Gastroenterol 11・33
  
  Pages : 5151-5155
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Nectin-like molecule-1/TSLL1/SynCAM3 : a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule localizing at non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes.2005
- Author(s)
  Kakunage S, Ikeda W, Itoh S, Deguchi-Tawarada M, Ohtsuka T, Mizoguchi A, Takai Y.
- Journal Title
  
  J Cell Sci. 118/Pt6
  
  Pages : 1267-1277
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Nectin-like molecule-1/TSLL1/SynCAM3 : a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule localizing at non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes.2005
- Author(s)
  Kakunaga S, Ikeda W, Itoh S, Deguchi-Tawarada M, Ohtsuka T, Mizoguchi A, Takai Y.
- Journal Title
  
  J Cell Sci. 118-Pt6
  
  Pages : 1267-1277
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Persistence of gene expression changes in noninflamed and inflamed colonic mucosa in ulcerative colitis and their presence in colonic carcinoma.2005
- Author(s)
  Toiyama Y, Mizoguchi A, Kimura K, Araki T, Yoshiyama S, Sakaguchi K, Miki C, Kusunoki M
- Journal Title
  
  World J Gastroenterol. 11・33
  
  Pages : 5151-5155
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Nectin-like molecule-1/TSLL1/SynCAM3 : a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule localizing at non-functional contact sites of presynaptic nerve terminals, axons and glia cell processes.2005
- Author(s)
  Kakunaga S, Ikeda W, Itoh S, Deguchi-Tawarada M, Ohtsuka T, Mizoguchi A, Takai Y.
- Journal Title
  
  J Cell Sci. 118・Pt6
  
  Pages : 1267-1277
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Persistence of gene expression changes in noninflamed and inflamed colonic mucosa in ulcerative colitis and their presence in colonic carcinoma.2005
- Author(s)
  Toiyama Y, Mizoguchi A, Kimura K, Araki T, Yoshiyama S, Sakaguchi K, Miki C, Kusunoki M
- Journal Title
  
  World J Gastroenterol. 11-33
  
  Pages : 5151-5155
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590142
[Journal Article] Nectin-Afadin細胞接着機構2004
- Author(s)
  溝口明
- Journal Title
  
  生体の科学 55・5
  
  Pages : 438-439
- Data Source
  KAKENHI-PROJECT-16001005
[Journal Article] Nectin-Afadin細胞接着機構2004
- Author(s)
  溝口明
- Journal Title
  
  生体の科学 55・5
  
  Pages : 438-439
- Data Source
  KAKENHI-PROJECT-16590142
[Presentation] Roles of afadin in the development of the cellular architecture of the hippocampus.2016
- Author(s)
  宮田宗明、丸尾知彦、山本昆明、垣内愛加、王淑杰、藤原武志、溝口明、萬代研二、高井義美
- Organizer
  第３９回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-26251013
[Presentation] ネクチン-2αとマウス手綱核2016
- Author(s)
  塩谷元、萬代研二、宮田宗明、丸尾知彦、垣内愛加、王淑杰、藤原武志、溝口明、望月秀樹、高井義美
- Organizer
  第３９回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-26251013
[Presentation] SBF-SEM 3D reconstitution analysis reveals alterations in composition and morphology of mouse hippocampal mossy fiber synapses by afadin knockout2015
- Author(s)
  Takeshi Fujiwara, Shujie Wang, Yu Itoh, Kousyoku Sai, Aika Kaito, Naoyuki Miyazaki, Kazuyoshi Murata, Tomohiko Maruo, Hideaki Yamamoto, Kenji Mandai, Yoshimi Takai, Akira Mizoguchi
- Organizer
  第120回日本解剖学会総会・全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-26251013
[Presentation] 敗血症モデルマウスにおける消化管微小循環とNeutrophil extracellular trapsの経時的観察と検討2014
- Author(s)
  小池勇樹、田中光司、井出正造、大竹耕平、井上幹大、内田恵一、毛利靖彦、溝口明、楠正人
- Organizer
  第114回日本外科学会
- Place of Presentation
  京都国際会館(京都)
- Year and Date
  2014-04-04
- Data Source
  KAKENHI-PROJECT-23591958
[Presentation] In vivo optical pathology of paclitaxel efficacy on the peritoneal metastatic xenografts of gastric cancer using multiphoton microscopy2013
- Author(s)
  Tanaka K, Shimura T, Okigami M, Toiyama Y, Morimoto Y, Kitajima T, Kondo S, Kawamura M, Saigusa S, Okugawa Y, Ohi M, Inoue Y, Uchida K, Araki T, Mohri Y, Mizoguchi A, Kusunoki M.
- Organizer
  2013 ASCO annual meeting
- Place of Presentation
  シカゴ、米国
- Year and Date
  2013-06-01
- Data Source
  KAKENHI-PROJECT-23591958
[Presentation] In vivo real-time imaging of tumor microcirculatory alterations in colorectal liver metastatic xenografts by chemotherapy using multiphoton microscopy. J Clin Oncol 30, 2012 (suppl; abstr e21053)2012
- Author(s)
  Koji Tanaka, Masato Okigami, Yuji Toiyama, Yuhki Morimoto, Kohei Matsushita, Mikio Kawamura, Kiyoshi Hashimoto, Susumu Saigusa, Yoshinaga Okugawa, Junichiro Hiro, Yasuhiro Inoue, Keiichi Uchida, Toshimitsu Araki, Yasuhiko Mohri, Akira Mizoguchi, Masato Kusunoki
- Organizer
  2012 ASCO Annual Meeting
- Place of Presentation
  Chicago, Illinois
- Data Source
  KAKENHI-PROJECT-23659646
[Presentation] Intravital assessment of infliximab efficacy in murine ulcerative colitis model using two photon laser scanning microscopy (P-76)2012
- Author(s)
  Kohei Matsushita, Koji Tanaka, Yuhki Morimoto, Masato Okigami, Mikio Kawamura, Kiyosi Hashimoto, Susumu Saigusa, Yuji Toiyama, Yuuki Koike, Yoshinaga Okugawa, Yasuhiro Inoue, Toshimitsu Araki, Keiichi Uchida, Yasuhiko Mohri, Akira Mizoguchi, and Masato Kusunoki
- Organizer
  The 6th Korea-Japan IBD Symposium
- Place of Presentation
  Keio Plaza Hotel Tokyo
- Year and Date
  2012-01-28
- Data Source
  KAKENHI-PROJECT-23659646
[Presentation] Time-series assessment of 5-fluorouracil efficacy on murine colorectal liver metastasis model using intravital multiphoton microscopy (2432)2012
- Author(s)
  Koji Tanaka, Masato Okigami, Yuhki Morimoto, Kohei Matsushita, Mikio Kawamura, Kiyoshi Hashimoto, Yuji Toiyama, Susumu Saigusa, Yoshinaga Okugawa, Yuhki Koike, Yasuhiro Inoue, Toshimitsu Araki, Keiichi Uchida, Yasuhiko Mohri, Akira Mizoguchi, Masato Kusunoki.
- Organizer
  AACR 103rdAnnual Meeting
- Place of Presentation
  Chicago Illinois
- Data Source
  KAKENHI-PROJECT-23659646
[Presentation] Intravital dual-colored visualization of colorectal liver metastasis formation in the living mice using two photon laser scanning microscopy (5278)2011
- Author(s)
  Koji Tanaka, Yuhki Morimoto, Kohei Matsushita, Mikio Kawamura, Yuji Toiyama, Susumu Saigusa, Yoshinaga Okugawa, Yuhki Koike, Yasuhiro Inoue, Chikao Miki, Akira Mizoguchi, Masato Kusunoki.
- Organizer
  AACR 102ndAnnual Meeting 2011
- Place of Presentation
  Orlando, Florida
- Data Source
  KAKENHI-PROJECT-23659646
[Presentation] Intravital evaluation of time-course efficacy of anticancer drugs on colorectal liver metastases in the same living mice using two-photon laser scanning microscopy. J Clin Oncol 29: 2011 (suppl; abstr 10621)2011
- Author(s)
  K. Tanaka, Y. Morimoto, Y. Toiyama, S. Saigusa, Y. Okugawa, Y. Inoue, K. Uchida, K. Matsushita, M. Kawamura, A. Mizoguchi, M. Kusunoki
- Organizer
  2011 ASCO Annual Meeting
- Place of Presentation
  Chicago, Illinois
- Data Source
  KAKENHI-PROJECT-23659646
[Presentation] Molecules regulating synapse formation and neural regeneration.2006
- Author(s)
  Mizoguchi A., at al.
- Organizer
  The 16th Interntinal Microscopy Congress.
- Place of Presentation
  Sapporo. Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300121
[Presentation] Molecules regulating synapse formation and neural regeneration2006
- Author(s)
  Mizoguchi, A., at. al.
- Organizer
  The 16th Interntinal Microscopy Congress
- Place of Presentation
  Sapporo. Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300121
[Presentation] 二光子励起顕微鏡を用いたマウス敗血症モデルにおける好中球・内皮細胞反応に対するAtIII製剤作用機序の生体内可視化
- Author(s)
  田中光司、沖上正人、小池勇樹、内田恵一、三枝晋、橋本清、志村匡信、問山裕二、奥川喜永、小林美奈子、井上靖浩、荒木俊光、毛利靖彦、溝口明、楠正人
- Organizer
  第25回日本外科感染症学会総会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23591958
[Presentation] SBF-SEM 3D reconstitution analysis reveals alterations in composition and morphology of mouse hippocampal mossy fiber synapses by afadin knockout.
- Author(s)
  Takeshi Fujiwara, Shujie Wang, Yu Itoh, Kousyoku Sai, Aika Kaito, Naoyuki Miyazaki, Kazuyoshi Murata, Tomohiko Maruo, Hideaki Yamamoto, Kenji Mandai, Yoshimi Takai, Akira Mizoguchi
- Organizer
  第１２０回日本解剖学会総会・全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-21227005

1. IDE Chizuka (70010080)

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MIZOGUCHI Akira 溝口 明

溝口 明

Research Projects

Research Products

Co-Researchers

ヒルシュスプルング病における腸管壁内神経節細胞局在の二光子レーザー顕微鏡観察研究Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Dynamic regulation of cerebellar neural circuits by "scrap and build" mechanismsOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生体蛍光染色剤とレーザー内視顕微鏡によるリアルタイム光学的組織診断法の開発Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Development of education movies demonstrating real-time biophysical phenomena by two photon laser microscopyPrincipal Investigator

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MIZOGUCHI Akira 溝口明

溝口明