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Shimono Yohei  下野 洋平

… Alternative Names

SHIMONO Yohei  下野 洋平

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Researcher Number 90594630
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-6256-4704
Affiliation (Current) 2025: 藤田医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2018 – 2025: 藤田医科大学, 医学部, 教授
2020: 神戸大学, 医学研究科, 准教授
2016 – 2017: 神戸大学, 医学研究科, 准教授
2011 – 2016: 神戸大学, 医学(系)研究科(研究院), 准教授
2014: 神戸大学, 大学院医学研究科, 准教授
2011: 神戸大学, 医学研究科, 准教授
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / Biological Sciences / Tumor biology / Tumor biology
Except Principal Investigator
Basic Section 49020:Human pathology-related / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 50010:Tumor biology-related / Basic Section 55010:General surgery and pediatric surgery-related / Functional biochemistry / Basic Section 59020:Sports sciences-related / Basic Section 55020:Digestive surgery-related / Basic Section 52040:Radiological sciences-related / Tumor biology
Keywords
Principal Investigator
乳がん / がん幹細胞 / マイクロRNA / アディポカイン / アディプシン / 卵巣がん / 脂肪細胞 / 細胞表面タンパク質 / CXCR4 / マイクロRNA … More / 乳腺組織発生 / がん浸潤 / 肝細胞増殖因子 / 自然免疫 / がん転移 / 組織発生 / エクソソーム / 異種移植マウス / 肝転移 / APC / WNTシグナル伝達系 / 休眠状態がん細胞 / 休眠がん細胞 / がん休眠 / ネクチン様分子 / がん関連線維芽細胞 / 翻訳後修飾 / 細胞表面蛋白質 … More
Except Principal Investigator
エストロゲン / アロマターゼ / エストロゲン受容体β / 右側 / 高齢者 / 結腸癌 / がん幹細胞 / 卵巣がん / 腫瘍間質 / がん / 脂肪細胞 / 乳がん / シグナル伝達 / アファディン / ネクチン / 異種細胞間接着 / 評価法 / 運動性溶血性貧血 / 食品添加 / 運動負荷 / 食習慣 / 振動負荷 / 試料撹拌機 / 動物実験 / 溶血 / 分泌因子 / DPP4 / 女性医学 / 食欲 / ニューロエストロゲン / 患者腫瘍組織移植モデル / 大腸癌 / エストロゲン濃度 / 右側癌 / 閉経後女性 / ミスマッチ修復タンパク質 / ESR2 CA repeat多型 / クロマチン / 転写調節因子 / ヒストン修飾 / 遺伝子発現 / 分化 / 栄養膜細胞 / 胎盤 / 大腸がんモデル / ER / 大腸がん / 治療標的 / リン酸化蛋白質 / 骨肉腫幹細胞 / 脳腫瘍 / リン酸化シグナル / リン酸化 / 分化転換 / Akt / アロマターゼ阻害薬 / Rab / 薬剤耐性 / CDK4/6 / パルボシクリブ / 難治性乳がん治療 / 細胞外小胞体 / miRNA / 放射線 / エクソソーム / 動物 / 癌 / PTEN / p53 / Hippo / がん抑制遺伝子 / 癌抑制遺伝子 / 細胞情報伝達機構 / 細胞膜受容体 / 細胞シグナル伝達機構 / 細胞接着・運動 / 神経シナプス / 上皮細胞 / 神経突起 / 肺腺がん / ネクチン様分子-5 / デスモソーム / アドヘレンスジャンクション / ネクチン様分子 / タイトジャンクション / アドへレンスジャンクション Less
  • Research Projects

    (21 results)
  • Research Products

    (147 results)
  • Co-Researchers

    (54 People)
  •  がん幹細胞の浸潤・転移誘導機構の統合的解析Principal Investigator

    • Principal Investigator
      下野 洋平
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Fujita Health University
  •  大腸癌のエストロゲン応答多様性の背景にある分子機構の解明

    • Principal Investigator
      本間 尚子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Toho University
  •  Mechanism of tumor progression mediated by secreted factors in adipocytes

    • Principal Investigator
      前田 真男
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Nagoya Keizai University
      Fujita Health University
  •  運動性溶血性貧血の新たな評価法の開発と予防を目的とした食習慣の提案

    • Principal Investigator
      木村 達志
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Ohka Gakuen University
  •  大腸癌に対するエストロゲン作用の多様性についての包括的研究

    • Principal Investigator
      本間 尚子
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Toho University
  •  遺伝子改変マウスを用いたニューロエストロゲンが摂食行動に与える影響

    • Principal Investigator
      西尾 永司
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Fujita Health University
  •  The roles of adipocytes in stemness regulationPrincipal Investigator

    • Principal Investigator
      下野 洋平
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Fujita Health University
  •  Signaling of protein phosphorylation in cancer stem cells for therapeutic target molecules

    • Principal Investigator
      Watanabe Takashi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Fujita Health University
  •  Study of colorectal cancer suppression mechanism by estrogen using the new colorectal cancer animal model

    • Principal Investigator
      Satou Harunobu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Fujita Health University
  •  The study of human trophoblast differentiation: epigenetic transcription regulation of aromatase gene

    • Principal Investigator
      Ishihara Naoe
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Fujita Health University
  •  Overcoming Molecular Targeted Drug Resistance in Aromatase Inhibitor-Resistant Breast Cancer.

    • Principal Investigator
      Hikichi Masahiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Fujita Health University
  •  integrated analysis of mechanisms promoting tumorigenesis by adipocyte

    • Principal Investigator
      Maeda Masao
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Fujita Health University
  •  Molecular mechanisms of cancer development and progression in obesity.Principal Investigator

    • Principal Investigator
      Shimono Yohei
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Fujita Health University
  •  Development of a new radiosensitizer utilizing the cell specificity of exosomes

    • Principal Investigator
      Inubushi Sachiko
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Kobe University
  •  Functions and regulations of tumor suppressor genes in vivo

    • Principal Investigator
      Suzuki Akira
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Tumor biology
    • Research Institution
      Kobe University
  •  Molecular basis for the establishment of early metastatic lesion through cell adaptationPrincipal Investigator

    • Principal Investigator
      Shimono Yohei
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor biology
    • Research Institution
      Kobe University
  •  Roles and modes of action of nectins in heterotypic cell-cell adhesions

    • Principal Investigator
      Takai Yoshimi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kobe University
  •  ヒト乳がん幹細胞の機能制御に関わる細胞表面タンパク質の解析Principal Investigator

    • Principal Investigator
      下野 洋平
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  乳がん幹細胞特異的マイクロRNAを指標としたニッチ関連細胞表面蛋白の解析Principal Investigator

    • Principal Investigator
      下野 洋平
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Screening and Functional Analyses of the MicroRNAs Involved in Cancer Cell DormancyPrincipal Investigator

    • Principal Investigator
      SHIMONO YOHEI
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Kobe University
  •  Roles of Cell Adhesion and Signaling in Cell Morphogenesis

    • Principal Investigator
      TAKAI YOSHIMI
    • Project Period (FY)
      2009 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kobe University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book Patent

  • [Book] がんの浸潤・転移-臨床と基礎-2011

    • Author(s)
      下野 洋平、信谷 健太郎、高井 義美
    • Total Pages
      241
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Journal Article] Monocyte-Derived miRNA-1914-5p Attenuates IL-1β?Induced Monocyte Adhesion and Transmigration2023

    • Author(s)
      Toriuchi Kohki、Kihara Toshie、Aoki Hiromasa、Kakita Hiroki、Takeshita Satoru、Ueda Hiroko、Inoue Yasumichi、Hayashi Hidetoshi、Shimono Yohei、Yamada Yasumasa、Aoyama Mineyoshi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 24 Issue: 3 Pages: 2829-2829

    • DOI

      10.3390/ijms24032829

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08211, KAKENHI-PROJECT-21H02650, KAKENHI-PROJECT-20K07052, KAKENHI-PROJECT-20K16939, KAKENHI-PROJECT-21K16403, KAKENHI-PROJECT-23K21387
  • [Journal Article] Adipocyte regulation of cancer stem cells2023

    • Author(s)
      Khaledian Behnoush、Thibes Lisa、Shimono Yohei
    • Journal Title

      Cancer Science

      Volume: 114 Issue: 11 Pages: 4134-4144

    • DOI

      10.1111/cas.15940

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15532, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K21387
  • [Journal Article] Upregulation of BMI1-suppressor miRNAs (miR-200c, miR-203) during terminal differentiation of colon epithelial cells2022

    • Author(s)
      Hisamori Shigeo、Mukohyama Junko、Koul Sanjay、Hayashi Takanori、Rothenberg Michael Evan、Maeda Masao、Isobe Taichi、Valencia Salazar Luis Enrique、Qian Xin、Johnston Darius Michael、Qian Dalong、Lao Kaiqin、Asai Naoya、Kakeji Yoshihiro、Gennarino Vincenzo Alessandro、Sahoo Debashis、Dalerba Piero、Shimono Yohei
    • Journal Title

      Journal of Gastroenterology

      Volume: Online ahead of print Issue: 6 Pages: 407-422

    • DOI

      10.1007/s00535-022-01865-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09076, KAKENHI-PROJECT-21K07152, KAKENHI-PROJECT-22K07010, KAKENHI-PROJECT-20K17687, KAKENHI-PROJECT-23K21387
  • [Journal Article] Transcriptional regulation of CYP19 by cohesin-mediated chromosome tethering in human granulosa cells2021

    • Author(s)
      Kotomura Naoe、Harada Nobuhiro、Shimono Yohei、Ishihara Satoru
    • Journal Title

      Biochemistry and Biophysics Reports

      Volume: 27 Pages: 101086-101086

    • DOI

      10.1016/j.bbrep.2021.101086

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09632
  • [Journal Article] Adipsin-Dependent Secretion of Hepatocyte Growth Factor Regulates the Adipocyte-Cancer Stem Cell Interaction2021

    • Author(s)
      Mizuno Masahiro、Khaledian Behnoush、Maeda Masao、Hayashi Takanori、Mizuno Seiya、Munetsuna Eiji、Watanabe Takashi、Kono Seishi、Okada Seiji、Suzuki Motoshi、Takao Shintaro、Minami Hironobu、Asai Naoya、Sugiyama Fumihiro、Takahashi Satoru、Shimono Yohei
    • Journal Title

      Cancers

      Volume: 13 Issue: 16 Pages: 4238-4238

    • DOI

      10.3390/cancers13164238

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02698, KAKENHI-PROJECT-20K07600, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-23K21387
  • [Journal Article] Local states of chromatin compaction at transcription start sites control transcription levels2021

    • Author(s)
      Ishihara Satoru、Sasagawa Yohei、Kameda Takeru、Yamashita Hayato、Umeda Mana、Kotomura Naoe、Abe Masayuki、Shimono Yohei、Nikaido Itoshi
    • Journal Title

      Nucleic Acids Research

      Volume: 49 Issue: 14 Pages: 8007-8023

    • DOI

      10.1093/nar/gkab587

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05789, KAKENHI-PROJECT-20H03223, KAKENHI-PROJECT-20K09632, KAKENHI-PROJECT-21K18876
  • [Journal Article] Upregulation of CIP2A in estrogen depletion‐resistant breast cancer cells treated with low‐dose everolimus2020

    • Author(s)
      Nishio Eiji、Hayashi Takanori、Akaza Mao、Hisatomi Yukiko、Hikichi Masahiro、Fujii Takuma、Utsumi Toshiaki、Harada Nobuhiro、Shimono Yohei
    • Journal Title

      FEBS Open Bio

      Volume: 10 Issue: 10 Pages: 2072-2080

    • DOI

      10.1002/2211-5463.12956

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09084, KAKENHI-PROJECT-20K09681, KAKENHI-PROJECT-18K07231
  • [Journal Article] Upregulation of S100A10 in metastasized breast cancer stem cells2020

    • Author(s)
      Yanagi Hisano、Watanabe Takashi、Nishimura Tatsunori、Hayashi Takanori、Kono Seishi、Tsuchida Hitomi、Hirata Munetsugu、Kijima Yuko、Takao Shintaro、Okada Seiji、Suzuki Motoshi、Imaizumi Kazuyoshi、Kawada Kenji、Minami Hironobu、Gotoh Noriko、Shimono Yohei
    • Journal Title

      Cancer Science

      Volume: 111 Issue: 12 Pages: 4359-4370

    • DOI

      10.1111/cas.14659

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07600, KAKENHI-PROJECT-19K22557, KAKENHI-PROJECT-18H02679, KAKENHI-PROJECT-18H02698, KAKENHI-PROJECT-18K07231, KAKENHI-PROJECT-19K23900
  • [Journal Article] miR-93 targets WASF3 and functions as a metastasis suppressor in breast cancer.2020

    • Author(s)
      Shibuya N, Kakeji Y, Shimono Y.
    • Journal Title

      Cancer Science

      Volume: 印刷中 Issue: 6 Pages: 2093-2103

    • DOI

      10.1111/cas.14423

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07231, KAKENHI-PROJECT-20H03752
  • [Journal Article] MicroRNA-9-5p-CDX2 Axis: A Useful Prognostic Biomarker for Patients with Stage II/III Colorectal Cancer.2019

    • Author(s)
      Nishiuchi A, Hisamori S, Sakaguchi M, Fukuyama K, Hoshino N, Itatani Y, Honma S, Maekawa H, Nishigori T, Tsunoda S, Obama K, Miyoshi H, Shimono Y, Taketo MM, Sakai Y.
    • Journal Title

      Cancers (Basel)

      Volume: 11 Issue: 12 Pages: 1891-1891

    • DOI

      10.3390/cancers11121891

    • NAID

      120006846477

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07196, KAKENHI-PROJECT-18K07231
  • [Journal Article] miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells.2019

    • Author(s)
      Mukohyama J, Isobe T, Hu Q, Hayashi T, Watanabe T, Maeda M, Yanagi H, Qian X, Yamashita K, Minami H, Mimori K, Sahoo D, Kakeji Y, Suzuki A, Dalerba P, Shimono Y.
    • Journal Title

      Cancer Research

      Volume: 79 Issue: 20 Pages: 5151-5158

    • DOI

      10.1158/0008-5472.can-18-3544

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07231, KAKENHI-PROJECT-19K17831, KAKENHI-PROJECT-16H05415, KAKENHI-PROJECT-17K16172, KAKENHI-PROJECT-17K16555
  • [Journal Article] Adipose-derived stem cells enhance human breast cancer growth and cancer stem cell-like properties through adipsin.2019

    • Author(s)
      Goto H, Shimono Y, Funakoshi Y, Imamura Y, Toyoda M, Kiyota N, Kono S, Takao S, Mukohara T, Minami H.
    • Journal Title

      Oncogene

      Volume: 38 Issue: 6 Pages: 767-779

    • DOI

      10.1038/s41388-018-0477-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07231
  • [Journal Article] Lack of association of ovariectomy-induced obesity with overeating and the reduction of physical activities.2019

    • Author(s)
      Nishio E, Hayashi T, Nakatani M, Aida N, Suda R, Fujii T, Wakatsuki T, Honda S, Harada N, Shimono Y.
    • Journal Title

      Biochemistry and Biophysics Reports

      Volume: 20 Pages: 100671-100671

    • DOI

      10.1016/j.bbrep.2019.100671

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07231, KAKENHI-PROJECT-17K16172
  • [Journal Article] F-Box/WD Repeat Domain-Containing 7 Induces Chemotherapy Resistance in Colorectal Cancer Stem Cells.2019

    • Author(s)
      Honma S, Hisamori S, Nishiuchi A, Itatani Y, Obama K, Shimono Y, Sakai Y.
    • Journal Title

      Cancers

      Volume: 11 Issue: 5 Pages: 635-635

    • DOI

      10.3390/cancers11050635

    • NAID

      120006644046

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07196, KAKENHI-PROJECT-18K07231
  • [Journal Article] miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells2019

    • Author(s)
      Junko Mukohyama, Taichi Isobe, Qingjiang Hu, Takanori Hayashi, Takashi Watanabe, Masao Maeda, Hisano Yanagi, Xin Qian, Kimihiro Yamashita, Hironobu Minami, Koshi Mimori, Debashis Sahoo, Yoshihiro Kakeji, Akira Suzuki, Piero Dalerba and Yohei Shimono
    • Journal Title

      Cancer Research

      Volume: 79 Pages: 5151-5158

    • Data Source
      KAKENHI-PROJECT-17H01400
  • [Journal Article] 3D Culture Represents Apoptosis Induced by Trastuzumab Better than 2D Monolayer Culture.2018

    • Author(s)
      Tatara T, Mukohara T, Tanaka R, Shimono Y, Funakoshi Y, Imamura Y, Toyoda M, Kiyota N, Hirai M, Kakeji Y, Minami H.
    • Journal Title

      Anticancer research

      Volume: 38 Pages: 2831-2839

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07231
  • [Journal Article] Glucose metabolism targeting therapy and withaferin A are effective for EGFR-TKI induced drug tolerant persisters.2017

    • Author(s)
      Kunimasa K, Nagano T, Shimono Y, Dokuni R, Kiriu T, Tokunaga S, Tamura D, Yamamoto M, Tachihara M, Kobayashi K, Satouchi M, Nishimura Y.
    • Journal Title

      Cancer Science

      Volume: 印刷中 Issue: 7 Pages: 1368-1377

    • DOI

      10.1111/cas.13266

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Journal Article] Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells2017

    • Author(s)
      Tominaga K, Shimamura T, Kimura N, Murayama T, Matsubara D, Kanauchi H, Niida A, Shimizu S, Nishioka K, Tsuji EI, Yano M, Sugano S, Shimono Y, Ishii H, Saya H, Mori M, Akashi K, Tada KI, Ogawa T, Tojo A, Miyano S, Gotoh N
    • Journal Title

      Oncogene

      Volume: 36(9) Issue: 9 Pages: 1276-1286

    • DOI

      10.1038/onc.2016.293

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-15H04294, KAKENHI-PROJECT-16J40231, KAKENHI-PROJECT-15K14381, KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-15H05325
  • [Journal Article] Discordance of MCM7 mRNA and its intronic microRNA levels under hypoxia.2017

    • Author(s)
      Kondo H, Shimono Y, Mukohyama J, Tanaka Y, Shibuya N, Minami H, Kakeji Y, Suzuki A.
    • Journal Title

      ANTICANCER RESEARCH

      Volume: 37(7) Issue: 7 Pages: 3885-3890

    • DOI

      10.21873/anticanres.11769

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-17H01400
  • [Journal Article] Hippo vs. Crab: tissue-specific functions of the mammalian Hippo pathway2017

    • Author(s)
      M. Nishio, T. Maehama, H. Goto, K. Nakatani, W. Kato, H. Omori, Y. Miyachi, H. Togashi, Y. Shimono and A. Suzuki
    • Journal Title

      Genes to Cells

      Volume: 22 Issue: 1 Pages: 6-31

    • DOI

      10.1111/gtc.12461

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26400205, KAKENHI-PROJECT-15K14381, KAKENHI-PROJECT-15K19026, KAKENHI-PROJECT-15K07020, KAKENHI-PROJECT-16K08626, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-17H01400
  • [Journal Article] Roles of microRNAs and RNA-binding proteins in the regulation of colorectal cancer stem cells.2017

    • Author(s)
      Mukohyama J, Shimono Y, Minami H, Kakeji Y, Suzuki A.
    • Journal Title

      CANCER

      Volume: 9(10) Issue: 10 Pages: 143-143

    • DOI

      10.3390/cancers9100143

    • NAID

      120006373809

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-17H01400, KAKENHI-PROJECT-16H05415, KAKENHI-PROJECT-17K16555
  • [Journal Article] Effect of Xenotransplantation Site on MicroRNA Expression of Human Colon Cancer Stem Cells2016

    • Author(s)
      Mukohyama J, Shimono Y, Yamashita K, Sumi Y, Mukohara T, Minami H, Kakeji Y
    • Journal Title

      Anticancer Research

      Volume: 36 Pages: 3679-3686

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Journal Article] A Novel Nectin-mediated Cell Adhesion Apparatus Which Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development2016

    • Author(s)
      Kitayama M, Mizutani K, Maruoka M, Mandai K, Sakakibara S, Ueda Y, Komori T, Shimono Y, Takai Y
    • Journal Title

      Journal of Biological Chemistry

      Volume: 291 Issue: 11 Pages: 5817-5831

    • DOI

      10.1074/jbc.m115.685917

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K14381, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-16K19035, KAKENHI-PROJECT-16K20411, KAKENHI-PROJECT-26860190
  • [Journal Article] Evaluation of the risk of lymphomagenesis in xenografts by the PCR-based detection of EBV BamHI W region in patient cancer specimens.2016

    • Author(s)
      Mukohyama J, Iwakiri, D, Zen Y, Mukohara T, Minami H, Kakeji Y, Shimono Y.
    • Journal Title

      Oncotarget

      Volume: 31 Issue: 31 Pages: 50150-50160

    • DOI

      10.18632/oncotarget.10322

    • NAID

      120005890089

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460932, KAKENHI-PROJECT-15K14381
  • [Journal Article] miR-137 Regulates the Tumorigenicity of Colon Cancer Stem Cells Through the Inhibition of DCLK12016

    • Author(s)
      Sakaguchi M, Hisamori S, Oshima N, Sato F, Shimono Y, Sakai Y
    • Journal Title

      Molecular Cancer Research

      Volume: 14 Issue: 4 Pages: 354-362

    • DOI

      10.1158/1541-7786.mcr-15-0380

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Journal Article] Regulation of CD44 expression and focal adhesion by Golgi phosphatidylinositol 4-phosphate in breast cancer2016

    • Author(s)
      Ijuin T, Takeuchi Y, Shimono Y, Fukumoto M, Tokuda E, Takenawa T
    • Journal Title

      Cancer Science

      Volume: 107 Issue: 7 Pages: 981-990

    • DOI

      10.1111/cas.12968

    • NAID

      120005866889

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14381, KAKENHI-PROJECT-16K08585
  • [Journal Article] Targeting the Hippo signalling pathway for cancer treatment2016

    • Author(s)
      K. Nakatani, T. Maehama, M. Nishio, H. Goto, W. Kato, H. Omori, Y. Miyachi, H. Togashi, Y. Shimono and A. Suzuki
    • Journal Title

      J. Biochem.

      Volume: 161 Pages: 237-244

    • DOI

      10.1093/jb/mvw074

    • NAID

      40021162008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26400205, KAKENHI-PROJECT-15K14381, KAKENHI-PROJECT-15K19026, KAKENHI-PROJECT-15K07020
  • [Journal Article] Organoid Culture of Human Cancer Stem Cells2016

    • Author(s)
      Shimono Y, Mukohyama J, Isobe T, Johnston DM, Dalerba P, Suzuki A
    • Journal Title

      Methods in Molecular Biology

      Volume: - Pages: 1-9

    • DOI

      10.1007/7651_2016_13

    • ISBN
      9781493976164, 9781493976171
    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Journal Article] Downregulation of CXCR4 in Metastasized Breast Cancer Cells and Implication in Their Dormancy2015

    • Author(s)
      Nobutani K, Shimono Y, Mizutani K, Ueda Y, Suzuki T, Kitayama M, Minami A, Momose K, Miyawaki K, Akashi K, Azuma T, Takai Y
    • Journal Title

      PLoS One

      Volume: 10 Issue: 6 Pages: e0130032-e0130032

    • DOI

      10.1371/journal.pone.0130032

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14381, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-26860190
  • [Journal Article] Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer2015

    • Author(s)
      Imamura Y, Mukohara T, Shimono Y, Funakoshi Y, Chayahara N, Toyoda M, Kiyota N, Takao S, Kono S, Nakatsura T, Minami H
    • Journal Title

      Oncol Rep

      Volume: 33 Issue: 4 Pages: 1837-1843

    • DOI

      10.3892/or.2015.3767

    • NAID

      120005758024

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23501268, KAKENHI-PUBLICLY-25130707, KAKENHI-PROJECT-15K08588, KAKENHI-PROJECT-26460627, KAKENHI-PROJECT-15K14381
  • [Journal Article] MicroRNA regulation of human breast cancer stem cells2015

    • Author(s)
      194.Shimono Y, Mukoyama J, Nakamura S, Minami H.
    • Journal Title

      J Clin Med

      Volume: 5 Issue: 1 Pages: 2-2

    • DOI

      10.3390/jcm5010002

    • NAID

      120005697222

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460627, KAKENHI-PROJECT-15K14381, KAKENHI-PROJECT-15K15066
  • [Journal Article] TYRO3 as a potential therapeutic target in breast cancer2014

    • Author(s)
      Ekyalongo RC, Mukohara T, Funakoshi Y, Tomioka H, Kataoka Y, Shimono Y, Chayahara N, Toyoda M, Kiyota N, Minami H
    • Journal Title

      Anticancer Res

      Volume: 34 Pages: 3337-3345

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Journal Article] Absence of primary cilia in cell cycle-arrested human breast cancer cells.2014

    • Author(s)
      Nobutani K, Shimono Y, Yoshida M, Mizutani K, Minami A, Kono S, Mukohara T, Yamasaki T, Itoh T, Takao S, Minami H, Azuma T, Takai Y.
    • Journal Title

      Genes Cells.

      Volume: 19 Issue: 2 Pages: 141-152

    • DOI

      10.1111/gtc.12122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-23501268, KAKENHI-PROJECT-24790284, KAKENHI-PUBLICLY-25130707
  • [Journal Article] TYRO3 as a potential therapeutic target in breast cancer2014

    • Author(s)
      Ekyalongo RC, Mukohara T, Funakoshi Y, Tomioka H, Kataoka Y, Shimono Y, Chayahara N, Toyoda M, Kiyota N, Minami H
    • Journal Title

      Anticancer Res

      Volume: 34 Pages: 3337-3345

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-25130707
  • [Journal Article] Suppression of the TGF-β1-induced protein expression of SNAI1 and N-cadherin by miR-199a.2014

    • Author(s)
      Suzuki T, Mizutani K, Minami A, Nobutani K, Kurita S, Nagino M, Shimono Y, Takai Y.
    • Journal Title

      Genes Cells.

      Volume: 19 Issue: 9 Pages: 667-675

    • DOI

      10.1111/gtc.12166

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-23501268, KAKENHI-PROJECT-24790283, KAKENHI-PROJECT-24790284, KAKENHI-PUBLICLY-25130707, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-26860190
  • [Journal Article] miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway2014

    • Author(s)
      Isobe T, Hisamori S, Hogan DJ, Zabala M, Hendrickson DG, Dalerba P, Cai S, Scheeren F, Kuo AH, Sikandar SS, Lam JS, Qian D, Dirbas FM, Somlo G, Lao K, Brown PO, Clarke MF, Shimono Y
    • Journal Title

      eLife

      Volume: 3

    • DOI

      10.7554/elife.01977

    • NAID

      120005697221

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23501268, KAKENHI-PUBLICLY-25130707
  • [Journal Article] Reduction of the ST6 β-galactosamide α-2,6-sialyltransferase 1 (ST6GAL1)-catalyzed sialylation of nectin-like molecule 2/cell adhesion molecule 1 and enhancement of ErbB2/ErbB3 signaling by microRNA-199a.2013

    • Author(s)
      Minami A, Shimono Y, Mizutani K, Nobutani K, Momose K, Azuma T, Takai Y.
    • Journal Title

      J Biol Chem.

      Volume: 288 Issue: 17 Pages: 11845-11853

    • DOI

      10.1074/jbc.m112.405993

    • NAID

      40019873148

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-23501268, KAKENHI-PROJECT-24790284, KAKENHI-PUBLICLY-23130510
  • [Journal Article] Interaction of Necl-4/CADM4 with ErbB3 and integrin α6 β4 and inhibition of ErbB2/ErbB3 signaling and hemidesmosome disassembly.2013

    • Author(s)
      Sugiyama H, Mizutani K, Kurita S, Okimoto N, Shimono Y, Takai Y.
    • Journal Title

      Genes Cells.

      Volume: 18 Issue: 6 Pages: 519-528

    • DOI

      10.1111/gtc.12056

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-23501268, KAKENHI-PROJECT-24790284, KAKENHI-PUBLICLY-23130510
  • [Journal Article] Immunoglobulin superfamily receptors and adherens junctions.2012

    • Author(s)
      Shimono, Y.
    • Journal Title

      Subcell Biochem.

      Volume: 60 Pages: 137-170

    • DOI

      10.1007/978-94-007-4186-7_7

    • ISBN
      9789400741850, 9789400741867
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-21500372, KAKENHI-PROJECT-22590828, KAKENHI-PROJECT-23501268, KAKENHI-PROJECT-24590354, KAKENHI-PUBLICLY-23122514, KAKENHI-PUBLICLY-23130510, KAKENHI-PUBLICLY-24111532
  • [Journal Article] 治療標的としてのヒト乳がん幹細胞2011

    • Author(s)
      南 晶洋、下野 洋平
    • Journal Title

      Bio Clinica 6月号 特集「癌幹細胞(CSC)」

      Volume: 26 Pages: 34-38

    • Data Source
      KAKENHI-PROJECT-23501268
  • [Journal Article] ヒト乳がん幹細胞-特性と幹細胞制御機構2011

    • Author(s)
      南 晶洋、下野 洋平
    • Journal Title

      実験医学増刊 がん幹細胞-ステムネス、ニッチ、標的治療への理解

      Volume: 20 Pages: 3247-3253

    • Data Source
      KAKENHI-PROJECT-23501268
  • [Patent] 抗がん剤2021

    • Inventor(s)
      下野洋平、佐谷秀行、前田真男
    • Industrial Property Rights Holder
      下野洋平、佐谷秀行、前田真男
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-137508
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Patent] 抗がん剤2019

    • Inventor(s)
      下野洋平、後藤秀彰、南博信
    • Industrial Property Rights Holder
      下野洋平、後藤秀彰、南博信
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Acquisition Date
      2020
    • Data Source
      KAKENHI-PROJECT-18K07231
  • [Presentation] 血中脂質に対する運動と魚油摂取の相互作用の検討2024

    • Author(s)
      木村達志,下野洋平,林孝典,渡辺睦行
    • Organizer
      日本栄養食糧学会
    • Data Source
      KAKENHI-PROJECT-22K11511
  • [Presentation] 脂肪細胞による乳がん幹細胞性促進機構2023

    • Author(s)
      Shimono Y, Mizuno M, Khaledian B, Goto H, Yoshida J, Funakoshi Y, Hayashi T, Munetsuna E, Maeda M, Asai N, Minami H, Kawada K
    • Organizer
      第20回日本臨床腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Adipsin-dependent adipocyte differentiation promotes the adipocyte-breast cancer stem cell interactions.2023

    • Author(s)
      Khaledian B, Yoshida J, Hayashi T, Mizuno M, Ushida K, Maeda M, Munetsuna E, Kawada K, Asai N, Shimono Y
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] 脂肪細胞によるがん幹細胞性制御機構2023

    • Author(s)
      Shimono Y, Goto H, Hayashi T, Khaledian B, Maeda M, Shibuya N, Kono S, Funakoshi Y, Kakeji Y, Minami H.
    • Organizer
      第34回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] 運動性溶血性貧血に関する評価指標の開発および食習慣や運動習慣の相違が及ぼす影響について2023

    • Author(s)
      木村達志,下野洋平,林孝典,渡辺睦行
    • Organizer
      日本血管血流学会
    • Data Source
      KAKENHI-PROJECT-22K11511
  • [Presentation] Lack of adipokine adipsin suppresses breast cancer invasion and metastasis.2023

    • Author(s)
      Hayashi T, Yoshida J, Munetsuna E, Khaledian B, Ushida K, Mizuno M, Maeda M, Asai N, Kawada K, Shimono Y
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] 脂肪細胞分泌因子アディプシンによるがん幹細胞性促進作用2023

    • Author(s)
      Shimono Y, Khaledian B, Mizuno M, Yoshida J, Gotoh N, Kawada K.
    • Organizer
      第9回がんと代謝研究会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] γ-Glutamylcyclotransferase, a novel regulator of cancer stem cell properties in breast cancer.2023

    • Author(s)
      Hayashi T, Okada S, Hirata M, Mizutani Y, Kijima Y, Suzuki M, Shimono Y
    • Organizer
      第20回 幹細胞シンポジウム
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Lower expression of Rab31 confers cancer stem cell properties and therapeutic resistance to the CDK4/6 inhibitor in breast cancer.2023

    • Author(s)
      Hou X, Hayashi T, Mizutani Y, Okada S, Suzuki M, Shimono Y
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Adipocytes promote cancer stem cell properties and metastatic progression of breast cancer cells through adipsin.2023

    • Author(s)
      Khaledian B, Yoshida J, Mizuno M, Maeda M, Hayashi T, Munetsuna E, Mizuno S, Mizutani Y, Okada S, Suzuki M, Sugiyama F, Takahashi S, Asai N, Kawada K, Shimono Y
    • Organizer
      第20回 幹細胞シンポジウム
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Identification of the epigenetic mechanism for colorectal cancer stem cell regulation through the comprehensive microRNA expression profiling of human colorectal cancer tissues.2023

    • Author(s)
      Mukohyama J, Itano O, Kakej Y, Shimono Y
    • Organizer
      ASCO Breakthrough
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] γ-Glutamylcyclotransferase enhances cancer stem cell properties in breast cancer.2023

    • Author(s)
      Sakai H, Hayashi T, Hirata M, Mizutani Y, Okada S, Kijima Y, Suzuki M, Shimono Y
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] γ-グルタミルシクロ転移酵素による乳がん幹細胞制御機構2022

    • Author(s)
      Shimono Y, Hayashi T, Maeda M, Asai N, Turtoi A, Soga Y
    • Organizer
      第8回 がんと代謝研究会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Analyses of terminally differentiated normal cells guide the identification of cancer stem cell-suppressor microRNAs.2022

    • Author(s)
      Shimono Y, Hisamori S, Mukohyama J, Isobe T, Kakeji Y, Dalerba P
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Rab31 is a potential biomarker and a negative regulator of a CDK4/6 inhibitor Palbociclib resistance in breast cancers.2022

    • Author(s)
      Hou X, Hayashi T, Harada N, Shimono Y
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Adipsin functions as promoter of the adipocyte-breast cancer stem cell interaction in the terminally differentiated adipocytes.2022

    • Author(s)
      Khaledian B, Mizuno M, Maeda M, Munetsuna E, Yoshida J, Asai N, Shimono Y
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] MicroRNA-mediated suppression of colon cancer stemness by the induction of terminal differentiation.2022

    • Author(s)
      Shimono Y, Hisamori S, Mukohyama J, Isobe T, Kakeji Y, Dalerba P
    • Organizer
      第33回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Distantly metastasized cancer stem cells in human breast cancer xenograft mouse.2022

    • Author(s)
      Shimono Y, Hayashi T, Kono S, Shibuya N, Hisamori S, Mukohyama J, Yanagi H, Watanabe T, Maeda M, Hirata M, Kakeji Y, Kawada K, Asai N, Okada S, Suzuki M, Takao S, Minami H, Kijima Y, Gotoh N, Dalerba P
    • Organizer
      The 6 th International Workshop on Humanized Mice
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Adipokine DPP4 enhances cancer stem cell-like properties in ovarian cancer.2022

    • Author(s)
      Maeda M, Nishio E, Hayashi T, Khaledian B, Ushida K, Okada S, Suzuki M, Asai N, Fujii T, Saya H, Shimono Y
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Hepatocyte growth factor is an adipokine that enhances breast cancer stem cell properties.2022

    • Author(s)
      Khaledian B, Mizuno M, Maeda M, Hayashi T, Mizuno S, Okada S, Suzuki M, Asai N, Sugiyama F, Takahashi S, Shimono Y
    • Organizer
      第19回 幹細胞シンポジウム
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Adipokine adipsin enhances the adipocyte-breast cancer stem cell interaction.2022

    • Author(s)
      Shimono Y, Mizuno M, Khaledian B, Goto H, Funakoshi Y, Maeda M, Hayashi T, Mizuno S, Okada S, Kijima Y, Suzuki M, Asai N, Sugiyama F, Takahashi S, Minami H
    • Organizer
      The12th AACR-JCA Joint Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Autocrine regulation of adipocytes promotes cancer stem cell properties in breast cancers.2021

    • Author(s)
      Khaledian B, Mizuno M, Maeda M, Takusagawa S, Yano M, Asai N, Shimono Y.
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] 脂肪細胞によるがん幹細胞性制御能の解析.2021

    • Author(s)
      Shimono Y, Gotoh N.
    • Organizer
      令和2年度金沢大学がん進展制御研究所共同利用・共同研究拠点研究成果報告会
    • Data Source
      KAKENHI-PROJECT-18K07231
  • [Presentation] Adipsin-dependent HGF secretion from adipocytes promotes cancer stem cell properties in breast cancer cells.2021

    • Author(s)
      Mizuno M, Khaledian B, Maeda M, Takusagawa S, Yano M, Asai N, Shimono Y.
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Role of S100A10 in the metastatic colonization of breast cancer stem cells.2021

    • Author(s)
      Shimono Y, Yanagi H, Watanabe T, Nishimura T, Hayashi T, Okada S, Suzuki M, Kawada K, Minami H, Gotoh N.
    • Organizer
      AACR Virtual Annual Meeting 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Application of organoids to breast cancer research.2021

    • Author(s)
      Shimono Y, Nishimura T, Kono S, Shibuya N, Yanagi H, Hayashi T, Watanabe T, Maeda M, Kakeji Y, Kawada K, Asai N, Takao S, Minami H, Kijima Y, Suzuki M, Gotoh N.
    • Organizer
      第80回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] 脂肪細胞はDPP4を分泌して卵巣がんのがん幹細胞性を促進する2021

    • Author(s)
      田草川栞里、前田真男、矢野愛佳、西尾永司、林孝典、岡田誠治、鈴木元、浅井直也、藤井多久磨、佐谷秀行、下野洋平
    • Organizer
      第80回 日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-19K09106
  • [Presentation] 脂肪細胞はMCP1を介して卵巣がんのがん幹細胞性を促進する2021

    • Author(s)
      矢野愛佳、前田真男、西尾永司、田草川栞里、林孝典、鈴木元、浅井直也、藤井多久磨、佐谷秀行、下野洋平
    • Organizer
      第80回 日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-19K09106
  • [Presentation] miR-93 targets WASF3 and functions as a metastasis suppressor in human breast cancer stem cells.2021

    • Author(s)
      Shimono Y, Shibuya N, Nishimura T, Gotoh N, Kakeji Y.
    • Organizer
      第18回 幹細胞シンポジウム
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Adipocytes enhance cancer stem cell-like properties in ovarian cancers through MCP1.2021

    • Author(s)
      Yano M, Maeda M, Nishio E, Takusagawa S, Suzuki M, Asai N, Fujii T, Saya H, Shimono Y.
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Adipocytes secrete DPP4 and enhance ovarian cancer stem cell-like properties in ovarian cancer.2021

    • Author(s)
      Takusagawa S, Maeda M, Yano M, Nishio E, Okada S. Suzuki M, Asai N, Fujii T, Saya H, Shimono Y.
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K21387
  • [Presentation] Gamma-glutamylcyclotransferase as a novel regulator of cancer stem cell properties in breast cancers.2020

    • Author(s)
      Hayashi T, Maeda M, Okada S, Suzuki M, ShimonoY.
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07231
  • [Presentation] Peritoneal adipose tissue-derived stem cells enhance clonogenicity of ovarian cancer cells.2020

    • Author(s)
      Maeda M, Hayashi T, Nishio E, Asai N, Fujii T, Shimono Y.
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07231
  • [Presentation] MicroRNA profiling of latently metastasized human breast cancer stem cells.2020

    • Author(s)
      Shimono Y, Shibuya N, Nishimura T, Gotoh N, Kakeji Y.
    • Organizer
      第79回日本癌学会学術総会 (International Session)
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07231
  • [Presentation] Upregulation of S100A10 in metastasized breast cancer stem cells.2020

    • Author(s)
      Yanagi H, Watanabe T, Nishimura T, Hayashi T, Okada S, Suzuki M, Minami H, Suzuki A, Kawada K, Gotoh N, Shimono Y.
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07231
  • [Presentation] Downregulation of miR-93 in micrometastatic cancer stem cells of human breast cancer xenograft.2019

    • Author(s)
      Shibuya N, Shimono Y, Minami H, Kakeji Y, Suzuki A.
    • Organizer
      第78回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07231
  • [Presentation] ヒト乳がん異種移植モデルの微小転移がん幹細胞で発現低下している マイクロRNA-93の解析2019

    • Author(s)
      渋谷 尚樹, 下野 洋平, 南 博信, 掛地 吉弘, 鈴木 聡.
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H01400
  • [Presentation] miR-221 targets an RNA-binding protein QKI-5 and enhances the tumorigenic capacity of human colorectal cancer stem cells.2019

    • Author(s)
      Shimono Y, Mukohyama J, Hayashi T, Watanabe T, Isobe T, Hu Q, Sahoo D, Minami H, Mimori K, Dalerba P, Kakeji Y, Suzuki A.
    • Organizer
      第17回 幹細胞シンポジウム
    • Data Source
      KAKENHI-PROJECT-18K07231
  • [Presentation] Adipsin is an adipokine that promotes cancer stem cell-like properties of breast cancer patient-derived xenograft cells.2019

    • Author(s)
      Shimono Y, Goto H, Funakoshi Y, Imamura Y, Toyoda M, Kiyota N, Kono S, Takao S, Mukohara T, Minami H.
    • Organizer
      第3回 三次元培養研究会
    • Data Source
      KAKENHI-PROJECT-18K07231
  • [Presentation] MOB1-YAP1は頭頸部扁平上皮癌発症の強力なドライバー経路である2018

    • Author(s)
      大森裕文, 西尾美希, 佐藤晋彰, 田口健一, 下野洋平, 三森功士, 益田宗幸, 鈴木 聡
    • Organizer
      日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-17H01400
  • [Presentation] ヒト乳がん異種移植モデルの微小転移がん幹細胞で発現低下しているマイクロRNA-25の解析2018

    • Author(s)
      渋谷尚樹、下野洋平、南博信、掛地吉弘、鈴木 聡
    • Organizer
      日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-17H01400
  • [Presentation] MicroRNA Regulation of Cancer Stem Cells in Human Solid Tumors2017

    • Author(s)
      Yohei Shimono
    • Organizer
      神戸大学・ワシントン大学・オスロ大学国際合同シンポジウム
    • Place of Presentation
      神戸
    • Year and Date
      2017-03-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] MicroRNA-mediated upregulation of the WNT signaling activities in human breast cancer stem cells.2017

    • Author(s)
      Shimono Y, Isobe T, Turtoi A, Mukohyama J, Mukohara T, Suzuki A, Castronovo V, Minami H.
    • Organizer
      Annual Meeting of the American Association for Cancer Research 2017.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01400
  • [Presentation] miR-221-QKI5 axis regulates tumorigenicity of human colorectal cancer stem cells.2017

    • Author(s)
      向山順子,下野洋平,磯部大地,Qingjiang Hu,渋谷尚樹,山下公大,三森功士,南 博信,掛地吉弘,鈴木 聡
    • Organizer
      第76回日本癌学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01400
  • [Presentation] 乳がん幹細胞の潜在転移に伴う独自の幹細胞性制御機構の獲得2017

    • Author(s)
      下野洋平,西村建徳,向山順子,渋谷尚樹,鈴木 聡,後藤典子
    • Organizer
      金沢大学がん進展制御研究所 共同利用・共同研究拠点シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H01400
  • [Presentation] Discordance of MCM7 mRNA and its intronic microRNA levels under hypoxia.2017

    • Author(s)
      渋谷尚樹,下野洋平,近藤弘基,向山順子,田中康照,掛地吉弘,南 博信,鈴木 聡
    • Organizer
      第76回日本癌学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01400
  • [Presentation] 早期転移乳がん幹細胞を特徴づける幹細胞性維持機構の解析2017

    • Author(s)
      下野 洋平、西村 建徳、向山 順子、鈴木 聡、後藤 典子
    • Organizer
      金沢大学がん進展制御研究所 共同利用・共同研究拠点シンポジウム
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] Role of Hippo pathway in vivo2017

    • Author(s)
      Miki Suzuki, Tomohiko Maehama, Hideru Togashi, Yohei Shimono, Akira Suzuki
    • Organizer
      神戸大学・ワシントン大学・オスロ大学国際合同シンポジウム
    • Place of Presentation
      神戸
    • Year and Date
      2017-03-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] ヒト大腸上皮の分化過程における腫瘍抑制的マイクロRNAの協調的発現上昇2017

    • Author(s)
      下野洋平、久森重夫、Piero Dalerba、磯部大地、向山順子、渋谷尚樹、掛地吉弘、南 博信、鈴木 聡
    • Organizer
      2017年度生命科学系学会合同年次大会ConBio.
    • Data Source
      KAKENHI-PROJECT-17H01400
  • [Presentation] Coordinated action of miRNAs for the regulation of normal and colon cancer stem cells.2017

    • Author(s)
      下野洋平,久森重夫,Piero Dalerba,向山順子,磯部大地,南 博信,鈴木 聡
    • Organizer
      第15回 幹細胞シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H01400
  • [Presentation] Coordinated action of tumor suppressive miRNAs for the suppression of normal and colon cancer stem cells2017

    • Author(s)
      下野洋平,久森重夫,向山順子,磯部大地,Piero Dalerba,鈴木 聡,南 博信
    • Organizer
      第15回日本臨床腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H01400
  • [Presentation] Identification of cancer-stem-cell-suppressor microRNAs through the analyses of human epithelial differentiation program2017

    • Author(s)
      下野洋平,久森重夫,磯部大地,向山順子,渋谷尚樹,掛地吉弘,南 博信,鈴木 聡
    • Organizer
      第76回日本癌学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01400
  • [Presentation] オルガノイド培養を用いた転移乳がん幹細胞の幹細胞性制御機構の解析2017

    • Author(s)
      下野洋平,西村建徳,鈴木 聡,後藤典子
    • Organizer
      第1回がん三次元培養研究会
    • Data Source
      KAKENHI-PROJECT-17H01400
  • [Presentation] Molecular characterization of dormant metastatic human breast cancer stem cells.2016

    • Author(s)
      Yohei Shimono, Tatsunori Nishimura, Junko Mukohyama, Taichi Isobe, Toru Mukohara, Noriko Gotoh, Hironobu Minami
    • Organizer
      第14回 幹細胞シンポジウム
    • Place of Presentation
      兵庫
    • Year and Date
      2016-05-20
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] 低酸素環境におけるMCM7とそのイントロン領域に存在するマイクロRNA-25の発現解離2016

    • Author(s)
      近藤 弘基、下野 洋平、向山 順子、鈴木 聡
    • Organizer
      第20回バイオ治療法研究会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] Evaluation of the risk of lymphomagenesis in xenografts by the detection of EBV BamHI W region in patient specimens2016

    • Author(s)
      Junko Mukohyama, Toru Mukohara, Hironobu Minami, Yoshihiro Kakeji, Yohei Shimono
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] The Hippo signaling Pathway: Function, Disorders, and Therapeutic Targeting2016

    • Author(s)
      Miki Nishio, Hiroki Goto, Yosuke Miyachi, Hideru Togashi, Yohei Shimono, Akira Suzuki
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] 遺伝子改変動物を利用した、形態形成におけるHippo経路の機能解析2016

    • Author(s)
      田中雅人、後藤裕樹、西尾美希、中谷圭佑、前濱朝彦、富樫 英、下野洋平、鈴木 聡
    • Organizer
      第48回日本臨床分子形態学会
    • Place of Presentation
      熊本
    • Year and Date
      2016-09-23
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] Upregulation of Oncogenic miR-221 in Human Colon Cancer Stem Cells2016

    • Author(s)
      Junko Mukohyama、Yohei Shimono、Toru Mukohaya、Yoshihiro Kakeji、Hironobu Minami
    • Organizer
      第14 回日本臨床腫瘍学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2016-07-28
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] 臓器への潜在転移に関わるヒト乳がん幹細胞の解析2016

    • Author(s)
      下野 洋平、向山 順子、西村 建徳、磯部 大地、向原 徹、鈴木 聡、後藤 典子、南 博信
    • Organizer
      第26日本サイトメトリー学会
    • Place of Presentation
      福岡
    • Year and Date
      2016-07-23
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] Role of Hippo pathway in vivo2016

    • Author(s)
      Miki Nishio、Hiroki Goto、Kohei Otsubo、Hideru Togashi、Yohei Shimono、Tomohiko Maehama、Akira Suzuki
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] Selectively upregulated miR-221 regulates the clonogenicity of human colon cancer stem cells.2016

    • Author(s)
      Naoki Shibuya, Junko Mukohyama, Taichi Isobe, Hiroki Kondo, Toru Mukohara, Yoshihiro Kakeji, Hironobu Minami, Akira Suzuki, Yohei Shimono
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] Identification of the proteins specific for human breast cancer stem cells2016

    • Author(s)
      Yohei Shimono
    • Organizer
      ベルギー大学訪問団シンポジウム
    • Place of Presentation
      神戸
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] Molecular characterization of quiescence and stemness of metastatic breast cancer stem cells: implication for their therapeutic resistance.2016

    • Author(s)
      Yohei Shimono, Junko Mukohyama, Tatsunori Nishimura, Noriko Gotoh, Hironobu Minami, Akira Suzuki
    • Organizer
      第41回内藤コンファレンス
    • Place of Presentation
      札幌
    • Year and Date
      2016-07-05
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] マイクロRNA研究の歴史と現状、ゲノム薬理学への応用について2015

    • Author(s)
      下野 洋平
    • Organizer
      第1回日本ゲノム薬理学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2015-02-14
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130707
  • [Presentation] Effect of the xenotransplantation site on the microRNA expression of human colorectal cancer stem cells2015

    • Author(s)
      Junko Mukohyama, Yohei Shimono, Yohei Funakoshi, Toru Mukohara, Yoshihiro Kakeji, Hironobu Minami
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] miR-142 upregulates miR-150 and confers an aberrant proliferative ability to human breast cancer stem cells2015

    • Author(s)
      Yohei Shimono, Taichi Isobe, Shigeo Hisamori, Michael Clarke
    • Organizer
      第13回 幹細胞シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2015-05-29
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] クロRNA研究の歴史と現状、ゲノム薬理学への応用について2015

    • Author(s)
      下野 洋平
    • Organizer
      第1回日本ゲノム薬理学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2015-02-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Presentation] 転移乳がん幹細胞の制御機構のパスウエイ解析2015

    • Author(s)
      下野 洋平
    • Organizer
      平成27年度がん進展制御研究所 共同利用・共同研究拠点研究成果報告会
    • Place of Presentation
      金沢
    • Year and Date
      2015-12-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] Cancer stem cells and drug resistance in human breast cancers2015

    • Author(s)
      Yohei Shimono
    • Organizer
      Joint Symposium of University of Liege & Kobe University
    • Place of Presentation
      神戸
    • Year and Date
      2015-05-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] Downregulation of CXCR4 in metastasized breast cancer cells and implication in their dormancy2015

    • Author(s)
      Yuki Ueda, Kentaro Nobutani, Yohei Shimono, Kiyohito Mizutani*, Toshihiro Suzuki*, Midori Kitayama*, Akihiro Minami, Kenji Momose, Kohta Miyawaki, Koichi Akashi, Takeshi Azuma, Yoshimi Takai
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K14381
  • [Presentation] 転移乳がん細胞におけるCXCR4の発現低下とがん休眠との関連2015

    • Author(s)
      上田悠貴、信谷健太郎、下野洋平、水谷清人、鈴木俊裕、北山美登里、南晶洋、百瀬健次、宮脇恒太、赤司浩一、東健、高井義美
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Presentation] Regulation of the Wnt signaling pathway by microRNA-142 upregulated in human breast cancer stem cells.2014

    • Author(s)
      Shimono, Y.
    • Organizer
      Keystone Symposia: Stem Cells and Cancer
    • Place of Presentation
      カナダ(バンフ)
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Presentation] Regulation of the Wnt signaling pathway by microRNA-142 upregulated in human breast cancer stem cells.2014

    • Author(s)
      Shimono, Y.
    • Organizer
      Keystone Symposia: Stem Cells and Cancer
    • Place of Presentation
      カナダ(バンフ)
    • Data Source
      KAKENHI-PUBLICLY-25130707
  • [Presentation] 幹細胞異常と内科系疾患、現状と展望: 幹細胞疾患とエピジェネティクス2013

    • Author(s)
      下野 洋平
    • Organizer
      第110回日本内科学会講演会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Presentation] 幹細胞異常と内科系疾患、現状と展望: 幹細胞疾患とエピジェネティクス2013

    • Author(s)
      下野 洋平
    • Organizer
      第110回日本内科学会講演会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130707
  • [Presentation] がん幹細胞研究:現状と将来展望2013

    • Author(s)
      下野 洋平
    • Organizer
      第11回日本臨床腫瘍学会学術集会
    • Place of Presentation
      東北大学百年記念会館(仙台)
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130707
  • [Presentation] がん幹細胞研究:現状と将来展望2013

    • Author(s)
      下野 洋平
    • Organizer
      第11回日本臨床腫瘍学会学術集会
    • Place of Presentation
      東北大学百年記念会館(仙台)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Presentation] Reduction of the sialylation of nectin-like molecule 2 and enhancement of the ErbB2/ErbB3 signaling by microRNA-199a.2013

    • Author(s)
      Shimono, Y.
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PUBLICLY-25130707
  • [Presentation] Reduction of the sialylation of nectin-like molecule 2 and enhancement of the ErbB2/ErbB3 signaling by microRNA-199a.2013

    • Author(s)
      Shimono, Y.
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Presentation] 遺伝子発現解析からみたヒトがん幹細胞の幹細胞性2012

    • Author(s)
      下野 洋平
    • Organizer
      平成23年度 文科省がん支援活動・厚労省対がん10カ年研究合同公開シンポジウム(招待講演)
    • Place of Presentation
      東京・学術総合センター
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Presentation] 遺伝子発現解析からみたヒトがん幹細胞の幹細胞性2012

    • Author(s)
      下野洋平
    • Organizer
      平成23年度文科省がん支援活動・厚労省対がん10カ年研究合同公開シンポジウム
    • Place of Presentation
      学術総合センター(東京都)(招待講演)
    • Year and Date
      2012-01-30
    • Data Source
      KAKENHI-PUBLICLY-23130510
  • [Presentation] MicroRNA Regulation of Human Breast Cancer Stem Cells and Normel Stem Cells2011

    • Author(s)
      下野洋平
    • Organizer
      第9回日本臨床腫瘍学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県)(招待講演)
    • Year and Date
      2011-07-22
    • Data Source
      KAKENHI-PUBLICLY-23130510
  • [Presentation] がん幹細胞理論と肺がん2011

    • Author(s)
      下野 洋平
    • Organizer
      第52回日本肺癌学会総会(招待講演)
    • Place of Presentation
      大阪・大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Presentation] MicroRNA Regulation of Human Breast Cancer Stem Cells and Normal Stem Cells2011

    • Author(s)
      下野 洋平
    • Organizer
      第9回日本臨床腫瘍学会学術集会(招待講演)
    • Place of Presentation
      横浜・パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Presentation] 癌幹細胞理論と肺癌2011

    • Author(s)
      下野洋平
    • Organizer
      第26回日本肺癌学会ワークショップ
    • Place of Presentation
      愛知県がんセンター(愛知県)(招待講演)
    • Year and Date
      2011-07-16
    • Data Source
      KAKENHI-PUBLICLY-23130510
  • [Presentation] がん幹細胞理論と肺がん2011

    • Author(s)
      下野洋平
    • Organizer
      第52回日本肺癌学会総会
    • Place of Presentation
      大阪国際会議場(大阪府)(招待講演)
    • Year and Date
      2011-11-04
    • Data Source
      KAKENHI-PUBLICLY-23130510
  • [Presentation] miR-142 regulates the tumorigenicity of human breast cancer stem cells

    • Author(s)
      Yohei Shimono, Shigeo Hisamori, Taichi Isobe
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PUBLICLY-25130707
  • [Presentation] マイクロRNA-199aはTGFβ-1で誘導されるSNAI1とN-cadherinの発現を 抑制する

    • Author(s)
      鈴木俊裕、水谷清人、南晶洋、信谷健太郎、梛野正人、下野洋平、 高井義美
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Presentation] HER/NF-κB induced IGF2 loop as a fundamental mechanism for breast cancer stem and niche cell maintenance

    • Author(s)
      Kana Tominaga、Teppei Shimamura、Yohei Shimono、Hideshi Ishii、Hideyuki Saya、Masaki Mori、Kei-ichiro Tada、Toshihisa Ogawa、Arinobu Tojo、Satoru Miyano、Noriko Gotoh
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PUBLICLY-25130707
  • [Presentation] miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway

    • Author(s)
      Yohei Shimono, Shigeo Hisamori, Taichi Isobe
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Presentation] がん幹細胞特異的マイクロRNAによるWNTシグナル伝達系制御機構

    • Author(s)
      下野 洋平
    • Organizer
      日本癌学会シンポジウム / 共同利用・共同研究拠点シンポジウム
    • Place of Presentation
      金沢
    • Year and Date
      2015-01-21 – 2015-01-22
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130707
  • [Presentation] マイクロRNA-199aはTGFβ-1で誘導されるSNAI1とN-cadherinの発現を抑制する

    • Author(s)
      鈴木俊裕、水谷清人、南晶洋、信谷健太郎、梛野正人、下野洋平、高井義美
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Presentation] miR-199a suppresses the TGF-β1-induced protein expression of SNAI1 and N-cadherin

    • Author(s)
      Toshihiro Suzuki、Kiyohito Mizutani、Akihiro Minami*、Kentaro Nobutani、Masato Nagino、Yohei Shimono、Yoshimi Takai
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Presentation] MicroRNA-mediated regulation of the human cancer stem cells.

    • Author(s)
      Yohei Shimono
    • Organizer
      札幌国際がんシンポジウム
    • Place of Presentation
      札幌
    • Year and Date
      2014-06-26 – 2014-06-28
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25130707
  • [Presentation] Effect of natural killer cell infiltration on the growth of the mouse xenografts tumors of human breast cancers.

    • Author(s)
      Junko Mukohyama、Yohei Shimono、Yohei Funakoshi、Toru Mukohara、Hiroshi Matsuoka、Yoshihiro Kakeji、Hironobu Minami
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Presentation] MicroRNA-mediated regulation of the human cancer stem cells.

    • Author(s)
      Yohei Shimono
    • Organizer
      The 33rd Sapporo International Cancer Symposium
    • Place of Presentation
      札幌
    • Year and Date
      2014-06-26 – 2014-06-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Presentation] Effect of natural killer cell infiltration on the growth of the mouse xenografts tumors of human breast cancers.

    • Author(s)
      Junko Mukohyama、Yohei Shimono、Yohei Funakoshi、Toru Mukohara、Hiroshi Matsuoka、Yoshihiro Kakeji、Hironobu Minami
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PUBLICLY-25130707
  • [Presentation] miR-199a suppresses the TGF-β1-induced protein expression of SNAI1 and N-cadherin

    • Author(s)
      Toshihiro Suzuki*、Kiyohito Mizutani、Akihiro Minami*、Kentaro Nobutani、Masato Nagino、Yohei Shimono、Yoshimi Takai
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PUBLICLY-25130707
  • [Presentation] Activation of the Canonical Wnt Signaling Pathway and Enhancement of the Tumorigenicity of Breast Cancer Stem Cells by MicroRNA-142

    • Author(s)
      Yohei Shimono, Taichi Isobe, Shigeo Hisamori, and Michael F. Clarke
    • Organizer
      第12回幹細胞シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2014-05-30 – 2014-05-31
    • Data Source
      KAKENHI-PUBLICLY-25130707
  • [Presentation] Activation of the Canonical Wnt Signaling Pathway and Enhancement of the Tumorigenicity of Breast Cancer Stem Cells by MicroRNA-142

    • Author(s)
      Yohei Shimono, Taichi Isobe, Shigeo Hisamori, and Michael F. Clarke
    • Organizer
      第12回幹細胞シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2014-05-30 – 2014-05-31
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Presentation] がん幹細胞特異的マイクロRNAによるWNTシグナル伝達系制御機構

    • Author(s)
      下野 洋平
    • Organizer
      日本癌学会シンポジウム / 共同利用・共同研究拠点シンポジウム
    • Place of Presentation
      金沢
    • Year and Date
      2015-01-21 – 2015-01-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-23501268
  • [Presentation] HER/NF-κB induced IGF2 loop as a fundamental mechanism for breast cancer stem and niche cell maintenance

    • Author(s)
      Kana Tominaga、Teppei Shimamura、Yohei Shimono*、Hideshi Ishii、Hideyuki Saya、Masaki Mori、Kei-ichiro Tada、Toshihisa Ogawa、Arinobu Tojo、Satoru Miyano、Noriko Gotoh
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-23501268
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