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KAWATA Sumio  河田 純男

ORCIDConnect your ORCID iD *help
… Alternative Names

河田 純男  カワタ スミオ

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Researcher Number 90183285
External Links
Affiliation (based on the past Project Information) *help 2008: 山形大学, 副学長
2000 – 2007: 山形大学, 医学部, 教授
1999 – 2000: Osaka University Graduate School of Medicine, Associate Professor, 医学系研究科, 助教授
1994 – 1998: 大阪大学, 医学部, 助教授
1996 – 1997: 大阪大学, 医学部, 教授 … More
1993: Osaka University, Internal Medicine, Assistant Professor, 医学部, 講師
1991 – 1992: 大阪大学, 医学部, 助手
1988 – 1989: 大阪大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Gastroenterology / Biological Sciences / 内分泌・代謝学
Except Principal Investigator
Gastroenterology / Gastroenterology / 内分泌・代謝学 / Pathological medical chemistry / Metabolomics
Keywords
Principal Investigator
肝細胞癌 / TGF-β / 増殖抑制因子 / 肝細胞 / 細胞増殖 / 大腸がん / 幹細胞 / TGF-βレセプター / 肝幹細胞 / oval cell … More / 脂肪肝 / VLDL / 肥満症 / HB-EGF / TGF-β受容体 / 酵素阻害剤 / 高TGF-β血症 / Ras p21 / manumycin / 遺伝子変異 / cell growth / TGF-β レセプター / TGF-b / TGF-b receptor / oval cells / Musashi-1 gene / 肝再生 / Notch signal / Matrigel / 骨髄細胞 / bone marrow cells / TPO / SCF / FGF2 / mRNA / apoB / sucrose / コリン欠乏食 / acetylーCoA carboxylase / TGFーβ / TGFーβレセプタ- / TGFーβ mRNA / 肝硬変症 / DNA合成 / ELISA / bioassay / 増殖因子 / 癌化 / 増殖抑制機構 / HGF / EGF / 受容体 / ras癌遺伝子産物 / フェルネシルトランスフェラーゼ / ファルネシルトランスフェラーゼ阻害剤 / 化学予防 / ファルネシル転移酵素 / 肝細胞移植 / musashi遺伝子 / 予後予測因子 / TGF-β1 / 再発予測因子 / NASH / 大腸腺腫 / 内臓脂肪 / adiponectin / インスリン抵抗性 / 大腸がん予防 / Triglyceride / apolipoprotein B mRNA / acetyl-CoA carboxylase / 脂肪蓄積機序 / 脂肪酸合成 / 動脈硬化 / 動脈平滑筋細胞 / ファルネシルトランスフェラーゼ / Rasp21 / ファネルシルトランスフェラーゼ / HPLC / 血管平滑筋細胞 / 増殖抑制 / Atherosclerosis / Vascular smooth muscle cells / Farnesyl ; protein transferase / hepatocellular cacinoma / TGF-beta receptor / Hepatocellular carcinoma / gene mutation / 抗TGF-β療法 / plasma TGF-b1 / anti-TGF-b therapy / Musashi遺伝子 / 肝癌細胞株 / Hepatic Stem cell / hepatocytes / Hepatoma cell lines / 肝線維化 / 肝硬変 / C型慢性肝炎 / アンギオテンジンII / アンギオテンジンII受容体 / 受容体阻害薬 / アンギオテンシンII / アンギオテンシンII受容体 / アンギオテンシン / アンギオテンシン受容体 / Hepatic fibrosis / hepatic cirrhosis / chronic hepatitis C / Angiotensin II receptor / angiotensin II / Musashi-1遺伝 / GFPトランスジェニックマウス / Musashi-1 / GFPトランスジェニック・マウス / oval cell line / Musashi-1遺伝子 / natchシグナル / Liver regeneration / Hepatic stem cells / GFP transgenic mice / 重症肝不全 / 自家骨髄移植 / 再生医療 / 肝不全 / 造血幹細胞増殖因子 / 劇症肝炎 / musashi-1 / hepatic failure / bone marrow cell transplantation / hepatic stem cells / liver regeneration therapy … More
Except Principal Investigator
HB-EGF / 増殖因子 / in vivo / 肝再生 / 肝細胞 / SNP / 類洞内皮細胞 / 遺伝子発現 / C型肝炎 / HCV / Ras / B-Raf / Rho / The ERM family / CD44 / Rab3A / Rabphilin-3A / 遺伝子治療 / HGF / c-Met / NK4 / 血管新生 / 治療 / liver regeneration / hepatocyte / growth factor / Flt-1 / Grap / signal transduction / 肝細胞癌 / 遺伝子多型 / Hepatitis C / TLR2 / HCV replicon / ヘパリン結合性EGF様増殖因子 / クッパー細胞 / 細胞間接着 / 抗カドヘリン抗体 / ファルネシルトランスフェラーゼ / ヒト癌 / 肝癌 / 大腸癌 / 発癌 / 遺伝子導入 / TM7SF2 / 脂質 / 脂質ラフト / 感染症 / siRNA / 胆石症 / コレステロール生合成 / 胆汁酸生合成 / コルステロール7αー水酸化酵素 / 肝ミクロソーム / cytosol protein / nonspecific lipid transfer protein / カルニチン / 長鎖脂肪酸 / ミトコンドリア / ミトコンドリアDNA / 心肥大 / 脂肪肝 / 心不全 / カルニチン輸送活性 / 総脂質 / トリアシルグリセロール / 高アンモニア血症 / 高脂血症 / 尿素サイクル / carnitine / cardiomegaly / mitochondria / long chain fatty acid / mit DNA / fatty liver / heart failure / carnitine transport activity / 低分子量GTP結合蛋白質 / 低分子量G蛋白質 / Rap1 / SmgGDS / SMAP / 14-3-3蛋白質 / ERM-CD44系 / small GTP-binding protein / 家族性高コレステロール血症 / HVJ-liposome法 / Familial hypercholesterolemia / HVJ-liposome method / Gene therapy / HGFアンタゴニスト / 腫瘍・癌 / 癌-間質相互作用 / 浸潤 / 転移 / 癌治療 / 浸潤・転移 / 浸潤・転移抑制剤 / 基底膜浸潤 / コラーゲンゲル内浸潤 / c-met / 癌細胞 / 腫瘍 / 癌浸潤・転移 / サイトカイン / レセプター / HGF antagonist / tumor / tumor-stromal interaction / invasion / metastasis / MB-EGF / 肝産生 / マウス / therapy / 動脈硬化 / 血管平滑筋細胞 / 形質変換 / 血管壁再構築3次元モデル / 内臓脂肪 / ノックアウトマウス / atherosclerosis / smooth muscle cell / transform / in vitro model of artery wall / visceral fat / 血管内皮細胞 / SH2蛋白 / angiogenesis / endothelial cel / hepatocellular carcinom / 可溶型HB-EGF / HVJ-リポソーム / soluble-HB-EGF / HVJ-liposome / gene therapy / 幹細胞癌 / 再発予防 / 癌ワクチン / 樹状細胞 / 免疫療法 / 癌ワクチン療法 / Hepatocellular carcinoma / Pervention / Cancer vaccine / Dendritic cell / Immunotherapy / 宿主 / 遺伝子多型性 / SNP感染感受性 / 細胞膜 / コホート / 糖鎖 / 感染感受性 / 接合蛋白 / ヘパラン硫酸 / 感染防御 / host / genetic polymorphism / susceptibility of infection / cell membrane / cohort / glycosylation / C型慢性肝炎 / 自然免疫 / Innate immune / Single nucleotide polymorphism Less
  • Research Projects

    (36 results)
  • Research Products

    (58 results)
  • Co-Researchers

    (43 People)
  •  Analysis of TM7SF2 Gene in Hepatitis C Virus Infection

    • Principal Investigator
      SAITO Takafumi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Yamagata University
  •  Functional dissection of a polymorphism in TLR2 gene associated with liver fibrosis in chronic hepatitis C

    • Principal Investigator
      LI Shao
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Yamagata University
  •  Development of liver regeneration therapy for severe hepatic failure.Principal Investigator

    • Principal Investigator
      KAWATA Sumio
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Yamagata University
  •  Analysis of Human Adaptor Protein Gene in Hepatitis C Virus Infection

    • Principal Investigator
      SAITO Takafumi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Yamagata University
  •  内臓脂肪蓄積による生体防御機能破綻を基盤とした消化器病態と分子機構の解明Principal Investigator

    • Principal Investigator
      河田 純男
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yamagata University
  •  Development of liver regeneration therapy against severe hepatic failure based on stem cell science -Differentiation and growth of hepatic stem cell and cell transplantation.Principal Investigator

    • Principal Investigator
      KAWATA Sumio
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Yamagata University
  •  大腸がんに新たに見出された高TGF-β血症の意義解明と戦略的治療法への応用―予後予測を基盤とした再発阻止のための抗TGF-β療法の開発―Principal Investigator

    • Principal Investigator
      河田 純男
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Yamagata University
  •  Antitumor immunotherapeutic effect of immunization with fusion of dendritic cells and hepatocellular carcinoma cells in mice

    • Principal Investigator
      SATO Koji
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Yamagata University
  •  Development of strategic therapy for severe hepatic failure using regenerative medicine-Isolation of hepatic stem cell expressing musashi-1 gene and cell therapyPrincipal Investigator

    • Principal Investigator
      KAWATA Sumio
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Yamagata University
  •  Development of hepatic anti-fibrotic therapy targeted to angiotensin II receptor antagonist-soppression of collagen production in the Ito cell via TGF-βPrincipal Investigator

    • Principal Investigator
      KAWATA Sumio
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Yamagata University
  •  肝幹細胞(liver stem cells)を用いた肝細胞移植療法の開発Principal Investigator

    • Principal Investigator
      河田 純男
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Yamagata University
  •  The mechanism for tumor angiogenesis in hepatocellular carcinoma : focused on the signal transduction pathway by Flt-1

    • Principal Investigator
      ITO Nobuyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  Study on the gene therapy of soluble-HB-EGF gene to accelerate liver regeneration.

    • Principal Investigator
      TAMURA Shinji
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  ファルネシル転移酵素を標的とした大腸がんの化学予防に関する基礎的研究Principal Investigator

    • Principal Investigator
      河田 純男
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  Atherosclerosis and knockout mouse of HB-EGF

    • Principal Investigator
      INUI Yoshiaki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Osaka University
  •  発癌・癌進展におけるras−ファルネシルトランスフェラーゼ発現の意義とその解明

    • Principal Investigator
      松田 幸彦
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  ALTERED GROWTH CONTROL OF HEPATOCYTES DURING THE CARCINOGENESIS AND ITS REGULATIONPrincipal Investigator

    • Principal Investigator
      KAWATA Sumio
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  Elevation of plasma TGF-b in cancer patients and study on its molecular mechanism.Principal Investigator

    • Principal Investigator
      KAWATA Sumio
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  Effect of HB-EGF on liver regeneration in vovo and its application as a therapeutic agent.

    • Principal Investigator
      TAMURA Shinji
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  細胞間接着弛緩による肝再生開始機構の解明-ヘパリン結合性FGF様増殖因子遺伝子発現機構の検討

    • Principal Investigator
      田村 信司
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  Study on abnormality in growth regulation hepatic carcinogenesis and its control.Principal Investigator

    • Principal Investigator
      KAWATA Sumio
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  Ras癌遺伝子産物を標的とした細胞増殖制御に関する基礎的研究-ファルネシルトランスフェラーゼ発現とその抑制Principal Investigator

    • Principal Investigator
      河田 純男
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  肝細胞の癌化に伴う増殖調節機構の異常とその制御-TGF-βレセプター構造異常の解析と遺伝子治療への応用-Principal Investigator

    • Principal Investigator
      河田 純男
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  新しい肝再生因子の発見とその肝細胞増殖促進機構の解明-ヘパリン結合性EGF様増殖因子の再生肝における遺伝子発現機構

    • Principal Investigator
      田村 信司
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  Inhibitory effects of HGF antagonist on invasion/metastasis of tumor cells.

    • Principal Investigator
      NAKAMURA Toshikazu
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  ヒト肝発癌過程における増殖抑制因子受容体の遺伝子異常の解析Principal Investigator

    • Principal Investigator
      河田 純男
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  cDNAs and antibodies for small GTP-binding proteins

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  Development of new drug therapy for atherosclerosisPrincipal Investigator

    • Principal Investigator
      KAWATA Sumio
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Osaka University
  •  Development of Therapy for Refractory Hyperlipidemia with LDL Receptor Gene Introduction by Lipofection Method

    • Principal Investigator
      MATSUZAWA Yuji
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Osaka University
  •  ヒト肝発癌過程における増殖因子・増殖抑制因子およびそれらの受容体遺伝子発現異常Principal Investigator

    • Principal Investigator
      河田 純男
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  肝硬変症からの発癌過程における増殖抑制機構の異常とその制御に関する研究Principal Investigator

    • Principal Investigator
      河田 純男
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  Role of Carnitine on Lipid and Carbohydrate Metagolism

    • Principal Investigator
      KUWAJIMA Masamichi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Osaka University
  •  肝細胞の癌化に伴なう増殖抑制機構の異常に関する分子生物学的研究Principal Investigator

    • Principal Investigator
      河田 純男
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  脂肪肝における脂肪蓄積機序に関する分子生物学的研究Principal Investigator

    • Principal Investigator
      河田 純男
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  肥満における脂肪肝の成因ーapolipoprotein B mRNA定量による検討Principal Investigator

    • Principal Investigator
      河田 純男
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  胆石症におけるコレステロールおよび胆汁酸生合成の調節機構に関する研究

    • Principal Investigator
      田島 幸児
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University

All 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book

  • [Book] Annual Review 消化器2007

    • Author(s)
      河田 純男
    • Publisher
      中外医学社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] What can be revealed by extending the sensitivity of HBsAg detection to below the present limit?2008

    • Author(s)
      Togashi H, Hashimoto C, Yokozawa J, Suzuki A, Sugahara K, Saito T, Yamaguchi I, Badawi H, Kainuma N, Aoyama M, Ohya H, Akatsuka T, Tanaka Y, Mizokami M, Kawata S
    • Journal Title

      Journal of Hepatology 49

      Pages: 17-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590746
  • [Journal Article] Common null variant, Arg192Stop, in a G-protein coupled receptor, olfactory receptor 1B1, associated with decreased serum cholinesterase activity2008

    • Author(s)
      Koyano S, Emi M, Toriyama S, Ishii M, Saito T, Makino N, Kubota I, Kato T, Kawata S
    • Journal Title

      Hepatology Research 38

      Pages: 696-703

    • NAID

      10021945389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590746
  • [Journal Article] Common null variant, Arg192Stop, in a G-protein coupled receptor, of factory receptor 1B1, associated with decreased serum cholinesterase activity2008

    • Author(s)
      Koyano S, Emi M, Saito T, Kawata S, et.al.
    • Journal Title

      Hepatology Research 38

      Pages: 696-703

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590746
  • [Journal Article] Association of the PIK3C2G gene polymorphisms with type 2 DM in a Japanese population2008

    • Author(s)
      Daimon M, Sato H, Oizumi T, Toriyama S, Saito T, Karasawa S, Jimbu Y, Wada K, Kameda W, Susa S, Yamaguchi H, Emi M, Muramatsu M, Kubota I, Kawata S, Kato T
    • Journal Title

      Biochem. Biophys. Res. Commun 365

      Pages: 466-471

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590746
  • [Journal Article] Association of the PIK3C2G gene polymorphisms with type 2 DM in a Japanese population2008

    • Author(s)
      Daimon M, Sato T, Saito T, Kawata S, et.al.
    • Journal Title

      Biochem Biophys Res Commun 365

      Pages: 466-471

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590746
  • [Journal Article] What can be revealed by extending the sensitivity of HBsAg detection to below the present limit2008

    • Author(s)
      Togashi H, Hashimoto C, Saito T, Kawata S, et.al.
    • Journal Title

      Journal of Hepatology 49

      Pages: 17-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590746
  • [Journal Article] Risk of hepatocellular carcinoma and secondary structure of hepatitis C virus (HCV) NS3 protein amino-terminus among patients with HCV subtype 1b2007

    • Author(s)
      Nishise Y, Saito T, Sugahara K, Ito J, Saito K, Togashi H, Nagano-Fujii M, Hotta H, Kawata S
    • Journal Title

      Journal of Infectious Diseases 196

      Pages: 1006-1009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590746
  • [Journal Article] Functional polymorphisms in the Toll-Like receptor 2 gene and liver fibrosis in chronic hepatitis C2007

    • Author(s)
      Shao L, Ishii K, Saito T, Watanabe H, Sugahara K, Nishise Y, Okumoto K, Ishii R, Kawata S, Ishikawa H, Fukao A
    • Journal Title

      Hepatol Inter 1

      Pages: 139-139

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590715
  • [Journal Article] Impaired portal circulation resulting from L-arginine deficiency in patients with lysinuric protein intolerance.2006

    • Author(s)
      Takeda T, Kawata S, et al.
    • Journal Title

      Gut 55

      Pages: 1526-1527

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Impaired portal circulation resulting from L-arginine deficiency in patients with lysinuric protein intolerance.2006

    • Author(s)
      Takeda T, Kawata S, et al.
    • Journal Title

      Gut Vol 55

      Pages: 1526-1527

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Association of transforming growth factor-beta l functionalpolymorphisms with natural cleorance of hepatitis C virus.2006

    • Author(s)
      Kimura T, Kawata S, et al.
    • Journal Title

      J Infect Dis Vol 193

      Pages: 1371-1374

    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Association of transforming growth factor-beta 1 functionalpolymorphisms with natural clearance of hepatitis C virus.2006

    • Author(s)
      Kimura T, Kawata S, et al.
    • Journal Title

      J Infect Dis Vol 193

      Pages: 1371-1374

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Characteristics of rat bone marrow cells differentiated into a liver cell lineage in the injured liver.2006

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      J Gastroenterol Vol 41

      Pages: 62-69

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Association of transforming growth factor-beta 1 functional polymorphisiiis with natural clearance of hepatitis C virus2006

    • Author(s)
      Kimura T, Saito T, Yoshimura M, Yixuan S, Baba M, JiG, Muramatsu M, Kawata S.
    • Journal Title

      J Infect Dis 193

      Pages: 1371-1374

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590715
  • [Journal Article] Characteristics of rat bone marrow cells differentiated into a liver lineage in the injured liver.2006

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      J Gastroenterol 41

      Pages: 62-69

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Association of transforming growth factor-beta 1 functional polymorphisms with natural clearance of hepatitis c virus.2006

    • Author(s)
      Kimura T, Kawata S, et al.
    • Journal Title

      J Infect Dis 193

      Pages: 1371-1374

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Differentiation of rat bone marrow cells cultured on artificial basement membrane containing extracellular marix into cell lineage.2005

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      J Hepatol Vol 43

      Pages: 110-116

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Association of visceral fat accumulation an plasma adiponectin with colorectal adenoma: evidence for participation of insulin resistance.2005

    • Author(s)
      Otake S, Kawata S, et al.
    • Journal Title

      Clin Cancer Res 11

      Pages: 3642-3646

    • Data Source
      KAKENHI-PROJECT-16046202
  • [Journal Article] Expression of Notch signal markers in bone marrow cells that differentiate a Liver cell lineage in a rat transplant model.2005

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      Hepatol Res 31

      Pages: 7-12

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390224
  • [Journal Article] Expression of Notch signaling markers in bone marrow cells that differentiate into a liver cell lineage in a rat transplant model.2005

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      Hepatol Res 31

      Pages: 7-12

    • NAID

      10015455865

    • Data Source
      KAKENHI-PROJECT-16046202
  • [Journal Article] NADPH oxidase plays a crucial role in PDGF-induced proliferation of hepatic stellate cells.2005

    • Author(s)
      Adachi T, Kawata S, et al.
    • Journal Title

      Hepatology 41

      Pages: 120-126

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Enhanced expression of suppressor of cytokine signaling-1 in the liver of chronic hepatist C : possible involvement in resistance to interferon therapy.2005

    • Author(s)
      Imanaka K, Kawata S, et al.
    • Journal Title

      J Viral Hepat 12

      Pages: 130-138

    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Hypermethylation of Chfr an hMLHl in gastric noninvasive and early invasive neoplasia.2005

    • Author(s)
      Homma N, Kawata S, et al.
    • Journal Title

      Virchow Arch 446

      Pages: 120-126

    • Data Source
      KAKENHI-PROJECT-16046202
  • [Journal Article] Enhanced expression of SOCS-1 in the liver of chronic hepatitis C.2005

    • Author(s)
      Imamura K, Kawata S, et al.
    • Journal Title

      J Viral Hepat 12

      Pages: 130-138

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390224
  • [Journal Article] Enhanced expression of SOCS-1 in the liver of chronic hepatitis C.2005

    • Author(s)
      Imanaka K, Kawata s, et al.
    • Journal Title

      J Viral Hepat 12

      Pages: 130-138

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390224
  • [Journal Article] Differenciation of rat bone marrow cells cultured on artificial basement membrane containing extracellular matri into cell lineage.2005

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      J Hepatol 43

      Pages: 110-116

    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Hypermethylation of Chfr and hMLH1 in gastric noninvasive and early invasive neoplasia.2005

    • Author(s)
      Homma N, Kawata S, et al.
    • Journal Title

      Virchow Arch 446

      Pages: 120-126

    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Expression of Notch signaling markers in bone marrow cells that differentiate into liver lineage in a rat transplant model.2005

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      Hepatol Res Vol 31

      Pages: 7-12

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Enhanced expression of suppressor of cytokine signaling-I in the liver of chronic hepatitis C : possible involevement in resistance to interferon therapy.2005

    • Author(s)
      Imanaka K, Kawata S, et al.
    • Journal Title

      J Viral Hepat 12

      Pages: 130-138

    • Data Source
      KAKENHI-PROJECT-15390224
  • [Journal Article] Expression of Notch signaling markers in bone marrow cells that differentiate into a liver cell lineage in a rat transplant model.2005

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      Hepatol Res 31

      Pages: 7-12

    • NAID

      10015455865

    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Expression of Notch signaling markers in bone marrow cell that differentiate Into a liver cell lineage in a rat transplant model.2005

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      Hepatol Res 31

      Pages: 7-12

    • NAID

      10015455865

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390224
  • [Journal Article] Differentiation of rat bone marrow cells cultured on artificial basement membrane containing extracellular matrix into liver cell lineage.2005

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      J Hepatol 43

      Pages: 110-116

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Association of visceral fat accumulation and plasma adiponectin with2005

    • Author(s)
      Otake S, Kawata S, et al.
    • Journal Title

      Cli Cancer Res (印刷中)

    • Data Source
      KAKENHI-PROJECT-16046202
  • [Journal Article] Enhanced expression of suppressor of cytokine signaling-1 in the liver of chronic hepatitis C: possible involvement in resistance to interferon therapy.2005

    • Author(s)
      Imanaka K, Kawata S, et al.
    • Journal Title

      J Viral Hepat 12

      Pages: 130-138

    • Data Source
      KAKENHI-PROJECT-16046202
  • [Journal Article] Expression of Notch signaling markers in bone marrow cells that differentiate into a liver cell lineage in a rat transplant model.2005

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      Hepatol Res 31

      Pages: 7-12

    • NAID

      10015455865

    • Data Source
      KAKENHI-PROJECT-15390224
  • [Journal Article] NADPH oxidase plays a crucial role in PDGF-induced proliferation of hepatic stellate cells.2005

    • Author(s)
      Adachi T, Kawata S, et al.
    • Journal Title

      Hepatology Vol 41

      Pages: 120-126

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Association of visceral fat accumulation and plasma adiponectin with colorectal adenoma : evidence for participation of insulin resistance.2005

    • Author(s)
      Otake S, Kawata S, et al.
    • Journal Title

      Clin Cancer Res 11

      Pages: 3642-3646

    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] NADPH oxidase plays a crucial role in PDGF-induced proliferation of hepatic stellate cells.2005

    • Author(s)
      Adachi T, Kawata S, et al.
    • Journal Title

      Hepatology 41

      Pages: 1272-1281

    • Data Source
      KAKENHI-PROJECT-16046202
  • [Journal Article] Differenciation of rat one marrow cells cultured on artificial basement membrane containing extracellular matri into cell lineage.2005

    • Author(s)
      Okuumoto K, Kawata S, et al.
    • Journal Title

      J Hepatol 43

      Pages: 110-116

    • Data Source
      KAKENHI-PROJECT-16046202
  • [Journal Article] Expression of Notch signaling markers in bone marrow cells that differentiate into liver cell lineage in rat transplant model.2005

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      Hepatol Res 31

      Pages: 7-12

    • NAID

      10015455865

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390214
  • [Journal Article] Promoter hypermethylation of DAP-kinase is associated with poor survival in primary biliary tract carcinoma patients.2004

    • Author(s)
      Tozawa T, Kawata S, et al.
    • Journal Title

      Cancer Sci 95

      Pages: 736-740

    • NAID

      10014197338

    • Data Source
      KAKENHI-PROJECT-16046202
  • [Journal Article] Possible contribution of circulating transforming growth factor- β1 to immunity and prognosis in unresectable hepatocellular carcinoma.2004

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      Liver International 24

      Pages: 21-28

    • Data Source
      KAKENHI-PROJECT-15390224
  • [Journal Article] Transmission of hepatitis C virus quasispeces between human adults.2004

    • Author(s)
      Saito T, Kawata S, et al.
    • Journal Title

      Hepatol Res 30

      Pages: 57-62

    • Data Source
      KAKENHI-PROJECT-15390224
  • [Journal Article] Genetic variation in humans associated with difference in the course of Hepatitis C.2004

    • Author(s)
      Saito T, Kawata S, et al.
    • Journal Title

      Biochem Biophys Res Commun 30

      Pages: 335-341

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390224
  • [Journal Article] Genetic variation in humans associated with differences in the course of hepatitis C.2004

    • Author(s)
      Saito T, Kawata S, et al.
    • Journal Title

      Biochem Biophys Res Commun 30

      Pages: 335-341

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390224
  • [Journal Article] Characteristics of patients with chronic hepatitis C who develop hepatocellular carcinoma after a sustained response to interferon therapy.2004

    • Author(s)
      Makiyama A, Kawata S, et al.
    • Journal Title

      Cancer 101

      Pages: 1616-1622

    • Data Source
      KAKENHI-PROJECT-16046202
  • [Journal Article] Demethylation of MAGE promoters during gastric cancer progression.2004

    • Author(s)
      Honda T, Kawata S, et al.
    • Journal Title

      Br J Cancer 90

      Pages: 838-843

    • Data Source
      KAKENHI-PROJECT-16046202
  • [Journal Article] Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia.2004

    • Author(s)
      Honda T, Kawata S, et al.
    • Journal Title

      Br J Cancer 90

      Pages: 2013-2016

    • Data Source
      KAKENHI-PROJECT-16046202
  • [Journal Article] Genetic variations in human associated with differences in the course of hepatitis C.2004

    • Author(s)
      Saito T, Kawata S, et al.
    • Journal Title

      Biochem Biophys Res Commun 30

      Pages: 335-341

    • Data Source
      KAKENHI-PROJECT-16046202
  • [Journal Article] Interferon treatment improves survival in chronic hepatitis C patients showing biochemical as well as virological responses by preventing liver-related death.2004

    • Author(s)
      Kasahara A, Kawata S, et al.
    • Journal Title

      J Viral Hepat 11

      Pages: 148-156

    • Data Source
      KAKENHI-PROJECT-15390224
  • [Journal Article] Liver regeneration in HB-EGF transgenic mice after partial hepatectomy.2003

    • Author(s)
      Kiso S, Kawata S, et al.
    • Journal Title

      Gastroenterology 124

      Pages: 701-707

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390224
  • [Journal Article] Differentiation of bone marrow cells into cells that express liver-specific genes Invitro.a a2003

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      Biochem Biophys Res Commun 304

      Pages: 691-695

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390224
  • [Journal Article] Separate of ASGR in the right and left hepatic lobe using 99Tc-GSA SPECT.2003

    • Author(s)
      Sugahara K, Kawata S, et al.
    • Journal Title

      Hepatology 38

      Pages: 1401-1409

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390224
  • [Journal Article] Differentiation of bone marrow cells into cells that express liver-specific genes In vitro.2003

    • Author(s)
      Okumoto K, Kawata S, et al.
    • Journal Title

      Biochem Biophys Res Commun 304

      Pages: 691-695

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390224
  • [Presentation] HCV NS3蛋白質二次構造の多型性とペグインターフェロン・リバビリン併用療法の効果予測2008

    • Author(s)
      斎藤貴史、堀田博、河田純男
    • Organizer
      第12回日本肝臓学会大会
    • Place of Presentation
      東京都
    • Year and Date
      2008-10-02
    • Data Source
      KAKENHI-PROJECT-19590746
  • [Presentation] Hyperprolactinemia associated with chronic hepatitis C and induction of prolactin expression in human peripheral blood mononuclear cells stimulated by hepatitis C virus2007

    • Author(s)
      Ishii R, Saito T, Shao L, Ugajin S, Sato C, Haga H, Suzuki A, Misawa K, Sanjo M, Nishise Y, Okumoto K, Ito J, Sugahara K, Saito K, Togashi H, Kawata S
    • Organizer
      58th AASLD
    • Place of Presentation
      Boston, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590715
  • [Presentation] Functional polymorphisms in the Toll-Like receptor 2 gene and liver fibrosis in chronic hepatitis C2007

    • Author(s)
      Shao L, Ishii K, Saito T, Watanabe H, Sugahara K, Nishise Y, Okumoto K, Ishii R, Kawata S, Ishikawa H, Fukao A
    • Organizer
      17th APASL
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590715
  • 1.  TAMURA Shinji (30243223)
    # of Collaborated Projects: 20 results
    # of Collaborated Products: 0 results
  • 2.  SAITO Takafumi (80250918)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 16 results
  • 3.  INUI Yoshiaki (00294067)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 4.  MATSUDA Yukihiko (90283770)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 5.  ITO Nobuyuki (30273668)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 6.  KISO Shinichi
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 7.  FUKUDA Kazuto
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 8.  SAITO Koji (90250919)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 4 results
  • 9.  MATSUZAWA Yuji (70116101)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 10.  TOGASHI Hitoshi (60192209)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 11.  WATANABE Hisayoshi (00332536)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  SHAO Li (80344787)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 13.  YAMASHITA Shizuya (60243242)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  TAKEMURA Kaoru (00161240)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  藤岡 滋典 (40218988)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  今井 康陽 (20201337)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  武田 弘明 (90236480)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  NAKANO Hirofumi
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  KUWAJIMA Masamichi (00205262)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  TAKAI Yoshimi (60093514)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SASAKI Takuya (40241278)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  TANAKA Kazuma (60188290)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  KANEDA Yasufumi (10177537)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  NOZAKI Syuichi (30252646)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  NAKAMURA Toshikazu (00049397)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  MONDEN Morito (00127309)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  FUNAKOSHI Hiroshi (40273685)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  MATSUMOTO Kunio (90201780)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  KOHNO Kenji (50142005)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  SUGAHARA Kazuhiko (70333953)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  ITO Junitsu (90344788)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  FUKAO Akira (80156736)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 33.  牧野 直彦 (10323164)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  田島 幸児 (60188240)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  片桐 修一 (80167337)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  川原 康洋 (80169755)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  中村 正 (90252668)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  根本 康夫 (30250088)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  KAYANOKI Yoshiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  中西 孝至
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  山崎 英二
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  石川 秀樹
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  KISO Shinich
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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