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NAKATA Hiroyasu  中田 裕康

ORCIDConnect your ORCID iD *help
… Alternative Names

中田 裕泰  ナカタ ヒロヤス

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Researcher Number 00041830
Other IDs
Affiliation (based on the past Project Information) *help 2008: Tokyo Metropolitan Organization for Medical Research, 東京都神経科学総合研究所, 研究員
2007 – 2008: Tokyo Metropolitan Organization for Medical Research, 東京都神経科学総合研究所, 研究員
2005 – 2006: (財)東京都医学研究機構, 東京都神経科学総合研究所, 副参事研究員
2000 – 2004: 財団法人東京都医学研究機構, 東京都神経科学総合研究所, 副参事研究員
1999 – 2000: 財団法人 東京都医学研究機構, 東京都神経科学総合研究所, 副参事研究員 … More
1998: 東京都神経科学総合研究所, 神経生化学, 副参事研究員
1995: (財)東京都神経科学総合研究所, 神経生化学研究部門, 副参事研究員
1995: TOKYO METROPOLITAN INSTITUTE FOR NEUROSCIENCE,DERT.OF MOLECULAR & CELLULAR NEUROBIOLOGY,STAFF SCIENTIST, 神経生化学研究部門, 副参事研究員
1993 – 1994: TOKYO METOROPOLITAN INSTITUTE FOR NEUROSCIENCES, 神経生化学, 副参事研究員
1993: (財)東京都神経科学総合研究所, 神経生化学研究部門, 副参事研究員
1992: 東京都神経科学総合研究所, 神経生化学, 副参事研究員 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / General pharmacology / Neurochemistry/Neuropharmacology / Functional biochemistry / 代謝生物化学 / General medical chemistry
Except Principal Investigator
医薬分子機能学
Keywords
Principal Investigator
ATP / アデノシン / プリン受容体 / アデノシン受容体 / ダイマー / P2受容体 / GPCR / adenosine / NECA / Gタンパク質共役受容体 … More / ダイマー形成 / 受容体 / P3 receptor / cross-talk / heterodimer / purinergic / クロストーク / 情報伝達 / ATP受容体 / Adenosine receptor / 細胞内情報伝達 / 血小板 / 免疫沈降 / 神経伝達 / ドーパミン受容体 / Gタンパク質 / オリゴマー / immunoprecipitation / platelet / purinergic receptor / dimer / ヘテロマー / 7回膜貫通受容体 / A2a受容体 / P2Y12 / P2Y1 / 血液凝固 / P2 receptor / signal transduction mechanism / 神経伝達抑制機構 / ATP receptor / cellular signal transduction mechanism / 情報伝達機構 / P3受容体 / ヘテロダイマー / 細胞内情報伝達機構 / プリナージック / Photoaffinity labeling / MAP kinase / Cell culture / Purinergic / リン酸化 / 細胞培養 / Gタンパク / 細胞情報伝達 / 培養細胞 / MAPキナーゼ / プリナ-ジック / Gene expression / Desensitization / Protein purification / Cloning / Purinergic receptor / Cellular signal transduction / 遺伝子発現 / 脱感作 / 蛋白精製 / クローニング / 分子モデリング / インターフェイス / BRET / 免疫染色 / タンパク融合 / パーキンソン病 / FRET … More
Except Principal Investigator
BRET / 免疫沈降法 / ヘテロ複合体 / 受容体複合体特異的抗体 / 両受容体融合タンパク質 / 線条体 / ホモ・ヘテロ複合体 / D_2R / ドーパミン受容体 / A_<2A>R / アデノシン受容体 Less
  • Research Projects

    (10 results)
  • Research Products

    (29 results)
  • Co-Researchers

    (7 People)
  •  Mechanism of G protein-coupled receptor oligomerizationPrincipal Investigator

    • Principal Investigator
      NAKATA Hiroyasu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  オリゴマー形成によるGタンパク質共役受容体の機能調節機構Principal Investigator

    • Principal Investigator
      中田 裕康
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  オリゴマー形成によるGタンパク質共役受容体の機能調節機構Principal Investigator

    • Principal Investigator
      中田 裕康
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Gタンパク質共役受容体のオリゴマー形成による機能調節機構Principal Investigator

    • Principal Investigator
      中田 裕康
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Regulation of GPCR function by oligomerizationPrincipal Investigator

    • Principal Investigator
      NAKATA Hiroyasu
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Gタンパク質共役型受容体ヘテロ複合体形成の解析と複合体作用薬開発への応用

    • Principal Investigator
      KAMIYA Toshio
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      医薬分子機能学
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Expression and function of hetereomeric purinergic receptorsPrincipal Investigator

    • Principal Investigator
      NAKATA Hiroyasu
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Structure and function of a new purinergic receptorPrincipal Investigator

    • Principal Investigator
      NAKATA Hiroyasu
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
      Tokyo Metropolitan Institute for Neuroscience
  •  STUDIES ON THE MOLECULAR MECHANISM OF CELLULAR TRANSDUCTION VIA ADENOSINE RECEPTORSPrincipal Investigator

    • Principal Investigator
      NAKATA Hiroyasu
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      TOKYO METROPOLITAN INSTITUTE FOR NEUROSCIENCE
  •  Studies on the molecular mechanism of cellular signal transduction via adenosine receptorsPrincipal Investigator

    • Principal Investigator
      NAKATA Hiroyasu
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      代謝生物化学
    • Research Institution
      TOKYO METOROPOLITAN INSTITUTE FOR NEUROSCIENCES

All 2008 2007 2006 2005 2004 Other

All Journal Article

  • [Journal Article] Synthesis of eudistomin D analogues and its effects on adenosine receptors2008

    • Author(s)
      Ishiyama, H., Ohshita, K., Abe, T., Nakata, H., obayashi
    • Journal Title

      Bioorg. Med. Chem 16

      Pages: 3825-3830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19036036
  • [Journal Article] Mitogen-activated protein kinase signaling is involved in suramin-induced neurite outgrowth in a neuronal cell line2007

    • Author(s)
      Nakata, H
    • Journal Title

      Biochem Biophys Res Commun 355

      Pages: 842-848

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19036036
  • [Journal Article] Mitogen-activated protein kinase signaling is involved in suramin-induced neurite outgrowth in a neuronal cell line2007

    • Author(s)
      Nakata, H
    • Journal Title

      Biochemical and Biophysical Research Communications 355

      Pages: 842-848

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19036036
  • [Journal Article] GPCRのヘテロダイマー形成2007

    • Author(s)
      中田 裕康
    • Journal Title

      日本薬理学雑誌 130

      Pages: 4-8

    • NAID

      10019813176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19036036
  • [Journal Article] Synthesis of hybrid molecules of caffeine and eudistomin D and its effects on adenosine receptors2007

    • Author(s)
      Ohshita, K., Ishiyama, H., Oyanagi, K., Nakata, H., Kobayashi, J
    • Journal Title

      Bioorg.Med. Chem. 15

      Pages: 3235-3240

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19036036
  • [Journal Article] Regulation of pharmacology by hetero-oligomerization between A_1 adenosine receptor and P2Y_2 receptor.2006

    • Author(s)
      Suzuki, T., Namba, K., Tsuga, H., Nakata, H.
    • Journal Title

      Biochem Biophys Res Commun. 351

      Pages: 559-565

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300125
  • [Journal Article] Clathrin required for phosphorylation and internalization of beta 2-adrenergic receptor by G protein-coupled receptor kinase 2 (GRK2).2006

    • Author(s)
      Mangmool, S., Haga, T., Kobayashi, H., Kim, KM., Nakata, H., Nishida, M., Kurose, H.
    • Journal Title

      J.Biol.Chem. 281

      Pages: 31940-31949

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300125
  • [Journal Article] Functional expression of single-chain heterodimeric G-protein-coupled receptors for adenosine and dopamine2005

    • Author(s)
      T.Kamiya, O.Saitoh, H.Nakata
    • Journal Title

      Cell Struct.Funct. 29

      Pages: 139-145

    • NAID

      10015462469

    • Data Source
      KAKENHI-PROJECT-16659078
  • [Journal Article] Functional expression of single-chain heterodimeric G-protein-coupled receptors for adenosine and dopamine.2005

    • Author(s)
      Kamiya, T., Saitoh, O., Nakata, H.
    • Journal Title

      Cell Struct. Funct. 29

      Pages: 139-145

    • NAID

      10015462469

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300125
  • [Journal Article] Identification of adenosine receptor subtypes expressed in the human endothelial-like ECV304 cells2005

    • Author(s)
      R.Kobayashi, O.Saitoh, H.Nakata
    • Journal Title

      Pharmacology 74

      Pages: 143-151

    • Data Source
      KAKENHI-PROJECT-16659078
  • [Journal Article] Identification of adenosine receptor subtypes expressed in the human endothelial-like ECV304 cells2005

    • Author(s)
      R.Kobayashi, O.Saitoh, H.Nakata
    • Journal Title

      Pharmacology 74

      Pages: 143-151

    • Data Source
      KAKENHI-PROJECT-17048035
  • [Journal Article] Identification of specific [3H]adenine binding sites in rat brain membranes2005

    • Author(s)
      S.Watanabe, M.Ikekita, H.Nakata
    • Journal Title

      J.Biochem. 137

      Pages: 323-329

    • NAID

      10017343832

    • Data Source
      KAKENHI-PROJECT-17048035
  • [Journal Article] Identification of adenosine receptor subtypes expressed in the human endothelial-like ECV304 cells2005

    • Author(s)
      R.Kobayashi, O.Saitoh, H.Nakata
    • Journal Title

      Pharmacology 74

      Pages: 143-151

    • Data Source
      KAKENHI-PROJECT-16300125
  • [Journal Article] Functions of heteromeric association between adenosine and P2Y receptors2005

    • Author(s)
      H.Nakata, K.Yoshioka, T.Kamiya, H.Tsuga, K.Oyanagi
    • Journal Title

      J.Mole.Neurosci 26

      Pages: 233-238

    • Data Source
      KAKENHI-PROJECT-16659078
  • [Journal Article] Identification of specific [3H]adenine binding sites in rat brain membranes2005

    • Author(s)
      S.Watanabe, M.Ikekita, H.Nakata
    • Journal Title

      J.Biochem. 137

      Pages: 323-329

    • NAID

      10017343832

    • Data Source
      KAKENHI-PROJECT-16300125
  • [Journal Article] Functional expression of single-chain heterodimeric G-protein-coupled receptors for adenosine and dopamine2005

    • Author(s)
      T.Kamiya, O.Saitoh, H.Nakata
    • Journal Title

      Cell Struct.Funct. 29

      Pages: 139-145

    • NAID

      10015462469

    • Data Source
      KAKENHI-PROJECT-17048035
  • [Journal Article] Functions of heteromeric association between adenosine and P2Y receptors2005

    • Author(s)
      H.Nakata, K.Yoshioka, T.Kamiya, H.Tsuga, K.Oyanagi
    • Journal Title

      J.Mole.Neurosci 26

      Pages: 233-238

    • Data Source
      KAKENHI-PROJECT-16300125
  • [Journal Article] Functional expression of single-chain heterodimeric G-protein-coupled receptors for adenosine and dopamine2005

    • Author(s)
      T.Kamiya, O.Saitoh, H.Nakata
    • Journal Title

      Cell Struct.Funct. 29

      Pages: 139-145

    • NAID

      10015462469

    • Data Source
      KAKENHI-PROJECT-16300125
  • [Journal Article] Functions of heteromeric association between adenosine and P2Y receptors2005

    • Author(s)
      H.Nakata, K.Yoshioka, T.Kamiya, H.Tsuga, K.Oyanagi
    • Journal Title

      J.Mole.Neurosci 26

      Pages: 233-238

    • Data Source
      KAKENHI-PROJECT-17048035
  • [Journal Article] Functions of heteromeric association between adenosine and P2Y receptors.2005

    • Author(s)
      Nakata, H.
    • Journal Title

      Journal of Molecular Neuroscience 26

      Pages: 233-238

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300125
  • [Journal Article] Functions of heteromeric association between adenosine and P2Y receptors.2005

    • Author(s)
      Nakata, H., Yoshioka, K., Kamiya, T., Tsuga, H., Oyanagi, K.
    • Journal Title

      J.Mole.Neurosci. 26

      Pages: 233-238

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300125
  • [Journal Article] Identification of specific [3H]adenine binding sites in rat brain membranes2005

    • Author(s)
      S.Watanabe, M.Ikekita, H.Nakata
    • Journal Title

      J.Biochem. 137

      Pages: 323-329

    • NAID

      10017343832

    • Data Source
      KAKENHI-PROJECT-16659078
  • [Journal Article] Identification of adenosine receptor subtypes expressed in the human endothelial-like ECV304 cells.2005

    • Author(s)
      Kobayashi, R., Saitoh, O., Nakata, H.
    • Journal Title

      Pharmacology 74

      Pages: 143-151

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300125
  • [Journal Article] Identification of specific [^3H]adenine binding sites in rat brain membranes.2005

    • Author(s)
      Watanabe, S., Ikekita, M., Nakata, H.
    • Journal Title

      J.Biochem. 137

      Pages: 323-329

    • NAID

      10017343832

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300125
  • [Journal Article] Purinergic-receptor oligomerization : Implications for neural functions in the central nervous system.2004

    • Author(s)
      Nakata, H.
    • Journal Title

      Neurotoxicity Research. 6

      Pages: 291-229

    • Data Source
      KAKENHI-PROJECT-16659078
  • [Journal Article] Purinergic-receptor oligomerization : Implications for neural functions in the central nervous system.2004

    • Author(s)
      Nakata, H.
    • Journal Title

      Neurotoxicity Research. 6

      Pages: 291-229

    • Data Source
      KAKENHI-PROJECT-16048231
  • [Journal Article] Ligand-induced rearrangement of the dimeric metabotropic glutamate receptor 1α.2004

    • Author(s)
      Tateyama, M., Abe, H., Nakata, H., Saito, O., Kubo, Y.
    • Journal Title

      Nature Struct Mol Biol. 11

      Pages: 637-642

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300125
  • [Journal Article] Heterogeneity of G protein-coupled receptor generated by post-translational mechanisms and its clinical meanings2004

    • Author(s)
      Tanoue, A, Koshimizu, T, Tsujimoto, G, Nakata, H, Hirose, S, Fukuzawa, T, Abe, J, Kurose, H.
    • Journal Title

      Nippon Yakurigaku Zasshi 124

      Pages: 235-243

    • NAID

      130000088789

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300125
  • [Journal Article] A highly conserved tryptophan residue in the fourth transmembrane domain of the A1 adenosine receptor is essential for ligand binding, but not receptor homodimerization

    • Author(s)
      Suzuki, T., Namba, K., Yamagishi, R., Kaneko, H., Haga, T., Nakata, H
    • Journal Title

      J. Neurochem

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19036036
  • 1.  SAITOH Osamu (60241262)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  TSUGA Hirofumi (00374158)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 3.  SUZUKI Tokiko (10415531)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 4.  KAMIYA Toshio (80344068)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  SAITOH Yoshiko (70241263)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  MIZUNO Kazuya (00219643)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  YOSHIOKA Kazuaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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