FUNAE Yoshihiko 舩江良彦

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FUNAE Yosihiko 船江良彦

HUNAE Yoshihiko 舩江良彦

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Researcher Number	00047268
Other IDs
Affiliation (based on the past Project Information) *help	2004 – 2005: 大阪市立大学, 大学院・医学研究科, 教授 1993 – 1999: 大阪市立大学, 医学部, 教授 1994 – 1995: 大阪市立大学, 医学部・化学研究室, 教授 1990 – 1991: 大阪市立大学, 医学部, 教授 1990: 大阪市立大学, 医学部, 教助 1988 – 1989: 大阪市立大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Risk sciences of radiation/Chemicals / Neurochemistry/Neuropharmacology Except Principal Investigator Urology / General physiology
Keywords	Principal Investigator PC12 cells / RNAi / Protein disulfide isomerase / Thyroid hormone / Bisphenol A / ドパミン分泌 / protein disulfide isomerase / 中枢神経系 / 内分泌攪乱化学物質 / 水酸化PCB … More / チロシン水酸化酵素 / PC12細胞 / Protein disulfide isomerase (PDI) / 甲状腺ホルモン / ビスフェノールA / Neuroactive compounds / Brain / Cytochrome P450 / 神経伝達物質 / 脳内アミン / ブフラロール / チトクロームP450 / チラミン / ドパミン / 神経化学 / 脳 / CYP2D / Cytochows P450 … More Except Principal Investigator チトクロームP450 / competitive RT-PCR / CYP4B1 / P450 / ESWL / P450アロマターゼ / CYP1A1 / がん原物質活性化 / Monoclonal antibody / Differentiation and maturation / Thymic lymphocytes / Endcrine hormones / Neurotransmitter / Synthesis and secretion / Biologically active factor / Thymus epithelial cell / ポリベブチドの分離・精製 / 生体防衛機構の個体発生と老化 / T細胞の分化・成熟 / ポリペプチドの分離・精製 / 分泌調節 / 神経・内分泌系 / 神経刺激伝達物質 / 分離・精製 / 高速液体クロマトグラフィ- / 胸腺ホルモン / 培養上清 / ラット胸腺上皮性細胞 / 単クロ-ン抗体 / 分化・成熟 / 胸腺リンパ球 / 内分泌ホルモン / 神経伝達物質 / 合成・分泌 / 胸腺生理活性物質 / 胸腺上皮性細胞 / peripheral lymphocyte / bladder tumor / cytochrome P450 / 分子生物学 / 膀胱癌 / 末梢血リンパ球 / 膀胱腫瘍 / SODIUM PENTOSAN POLYSULFATE / CITRATE / VITAMIN B6 DEFICIENCY / AUTORADIOGRAPHY / OXALIC ACID / CALCIUM OXALATE STONE / KIDNEY STONE / ビタミンD6欠乏 / ペントサンポリサルフェイト / クエン酸 / ビタミンB6欠乏 / オートラジオグラフィー / 蓚酸 / 蓚酸カルシウム結石 / 尿路結石 / Lung cancer / Genetic polymorphism / Metabolic activation / Mutation assay / Salmonella typhimurium / CYP3A4 / 遺伝子導入マウス / Ahレセプター / アロマターゼ / CYP1A2 / 発現系 / 発現制御 / DNAアダクト / トランスジェニックマウス / がん原物質 / 肺がん / 遺伝子多型 / 代謝的活性化 / 変異原性試験 / サルモネラ菌 / long-term results of ESWL / urinary infection / urinary obstruction / renal function / 過蓚酸尿症ラット / オ-トラジオグラフ / 蓚酸塩結石 / 蓚酸の薬理動態 / 衝撃波の生体への影響 / 尿路結石症 / 体外衝撃波結石破砕術 / Shock wave / ESWL長期予後 / 尿路感染症 / 閉塞性尿路障害 / 腎機能 / 一酸化窒素合成酵素 / CYP2B6 / 遺伝子導入動物 / 遺伝子発現 / ミクロソーム / ミトコンドリア / 細胞内局在性 / 分子多様性 / 薬物の酸化的代謝 / 脂溶性生理活性物質 / ヘム蛋白質 Less

The molecular of mechanism thyroid hormone disruption by bisphenol APrincipal Investigator
- Principal Investigator
  
  FUNAE Yoshihiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Osaka City University
Metabolic activation of procarcinogens and cancer risk
- Principal Investigator
  
  KAMATAKI Tetsuya
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
The role of Cytochrome P450 2D in the synthetic and/or metabolic pathways of endogenous neuroactive compoundsPrincipal Investigator
- Principal Investigator
  
  FUNAE Yoshihiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka City University
Molecular epidemiology of bladder cancer
- Principal Investigator
  
  YAMAMOTO Keisuke
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Osaka City University
EVALUATION OF EFFECT OF SODIUM PENTOSAN POLYSULFATE (SPP) AND CITRATE ON STONE FORMATION IN HYPEROXALURIC RATS BY RADIOLUMINOGRAPHY USING ^<14>C-OXALATE
- Principal Investigator
  
  YAMAMOTO Keisuke
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  OSAKA CITY UNIVERSITY
チトクロームP450を利用したがん原性のシュミレーションと発がんの感受性の解析
- Principal Investigator
  
  KAMATAKI Tetsuya
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
チトクロームPー450の分子生物学:発現の分子機構
- Principal Investigator
  
  藤井義明
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Effect of shock wave exposure during ESWL on renal function
- Principal Investigator
  
  KISHIMOTO Taketoshi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Osaka City University
Study on the Regulation of Thymic Hormone Secretion by Neural and Endocrine System-Using Primary Culture System of the Thymic Hormone-Secreting (Thymus Epthelial) Cells-
- Principal Investigator
  
  KINOSHITA Yoshihiro
- Project Period (FY)
  1988 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  General physiology
- Research Institution
  Osaka City University

All 2006 2005 2004 Other

All Journal Article Book

[Book] 生体統御システムと内分泌攪乱2005
- Author(s)
  舩江良彦
- Total Pages
  6
- Publisher
  シュプリンガー・フェアラーク
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310045
[Journal Article] Bisphenol A binds to Protein Disulfide Isomerase and inhibits its enzymatic and hormone-binding activities.2006
- Author(s)
  Hiroi T., Okada K., Osada M., Funae Y.
- Journal Title
  
  Endocrinology 147
  
  Pages: 2773-2780
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310045
[Journal Article] Inhibitory effects of environmental chemicals on protein disulfide isomerase in vitoro2005
- Author(s)
  Okada K., Hiroi T., Imaoka S., Funae Y.
- Journal Title
  
  Osaka City Medical Journal 51
  
  Pages: 51-63
- Data Source
  KAKENHI-PROJECT-16310045
[Journal Article] Inhibitory effects of environmental chemicals on protein disulfide isomerase in vitro.2005
- Author(s)
  Okada K., Hiroi T., Imaoka S., Funae Y.
- Journal Title
  
  Osaka city medical journal 51s
  
  Pages: 51-63
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310045
[Journal Article] Bisphenol A, an environmental endocrine-disrupting chemical, inhibits hypoxic response via degradation of hypoxia-inducible factor 1alpha (HIF-1alpha): structural requirement of bisphenol A for degradation of HIF-1alpha.2004
- Author(s)
  Kubo T., Maezawa N., Osada M., Katsumura S., Funae Y., Imaoka S.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 318
  
  Pages: 1006-1011
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310045
[Journal Article] Apigenin suppresses the expression of VEGF, an important factor For angiogenesis, in endothelial cells via degradation of HIF-1 alpha protein.2004
- Author(s)
  Osada M., Imaoka S., Funae Y.
- Journal Title
  
  FEBS LETTERS 575
  
  Pages: 59-63
- Data Source
  KAKENHI-PROJECT-16310045
[Journal Article] Effect of genetic polymorphism on the metabolism of endogenous neuroactive substances, progesterone and p-tyramine, catalyzed by CYP2D62004
- Author(s)
  Niwa T., Hiroi T., Tsuzuki D., Yamamoto S., Narimatsu S., Fukuda T., Azuma J., Funae Y.
- Journal Title
  
  MOLECULAR BRAIN RESEARCH 129
  
  Pages: 117-123
- Data Source
  KAKENHI-PROJECT-16310045
[Journal Article] Effect of bisphenol A on central nervous systems.2004
- Author(s)
  Funae Y., Okada K., Hiroi T.
- Journal Title
  
  Toxicol.Appl.Pharmacol. 197
  
  Pages: 229-229
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310045
[Journal Article] Effect of bisphenol A on central nervous systems.2004
- Author(s)
  Funae Y., Okada K., Hiroi T.
- Journal Title
  
  TOXICOLOGY AND APPLIED PHARMACOLOGY 197
  
  Pages: 229-229
- Data Source
  KAKENHI-PROJECT-16310045
[Journal Article] The roles of amino acid residues at positions 43 and 45 in microsomal contents and enzymatic functions of rat CYP2D1 and CYP2D22004
- Author(s)
  Narimatsu S., Imoto K., Isobe T., Kiryu K., Naito S., Hichiya H., Funae Y., et al.
- Journal Title
  
  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 324
  
  Pages: 627-633
- Data Source
  KAKENHI-PROJECT-16310045
[Journal Article] Effect of bisphenol A on central nervous systems.2004
- Author(s)
  Funae Y., et al.
- Journal Title
  
  Toxicol.Appl.Pharmacol. 197
  
  Pages: 229-229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310045
[Journal Article] Bisphenol A binds to protein disulfide isomerase and inhibits its isomerase and hormone-binding activities
- Author(s)
  Hiroi T., Okada K., Imaoka S., Osada M., Funae Y.
- Journal Title
  
  Endocrinology (In press)
- Data Source
  KAKENHI-PROJECT-16310045

1. KAMATAKI Tetsuya (00009177)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. YAMAMOTO Keisuke (70137230)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. IMAOKA Susumu (60145795)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 川尻要 (50142112)

# of Collaborated Projects: 2 results

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5. 江角浩安 (70160364)

# of Collaborated Projects: 2 results

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6. 原田信広 (00189705)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 杉山雄一 (80090471)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KISHIMOTO Taketoshi (00047078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OCHI Hironobu (70047067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SAKAMOTO Wataru (00215667)

# of Collaborated Projects: 1 results

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11. TAKAHASHI Yoshiki (80292019)

# of Collaborated Projects: 1 results

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12. NAKAYAMA Kazuo (20261323)

# of Collaborated Projects: 1 results

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13. ARIYOSHI Noritaka (00243957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. FUJITA Ken-ichi (60281820)

# of Collaborated Projects: 1 results

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15. SUGIMURA Kazunobu (90187659)

# of Collaborated Projects: 1 results

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16. IKEMOTO Shinichi (90168154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HIROI Toyoko (30305643)

# of Collaborated Projects: 1 results

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18. YOSHIDA Noriyuki (10363996)

# of Collaborated Projects: 1 results

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19. KINOSHITA Yoshihiro (80046896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KITAMURA Kenji (40214811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TOMINAGA Keiko (70217545)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. HATO Fumihiko (00198772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 藤井義明 (00098146)

# of Collaborated Projects: 1 results

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24. 田代裕 (40077558)

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25. 清水透 (40118956)

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26. 楠瀬正道 (10046766)

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27. 十川和博 (80175421)

# of Collaborated Projects: 1 results

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28. 中谷達也 (40183511)

# of Collaborated Projects: 1 results

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29. 島田力 (50158961)

# of Collaborated Projects: 1 results

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30. 豊川奉 (90172741)

# of Collaborated Projects: 1 results

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31. TERANO Yoshitake

# of Collaborated Projects: 1 results

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FUNAE Yoshihiko 舩江 良彦

FUNAE Yosihiko 船江 良彦

HUNAE Yoshihiko 舩江 良彦

Research Projects

Research Products

Co-Researchers

The molecular of mechanism thyroid hormone disruption by bisphenol APrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Metabolic activation of procarcinogens and cancer risk

Principal Investigator

Project Period (FY)

Research Category

Research Institution

The role of Cytochrome P450 2D in the synthetic and/or metabolic pathways of endogenous neuroactive compoundsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular epidemiology of bladder cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EVALUATION OF EFFECT OF SODIUM PENTOSAN POLYSULFATE (SPP) AND CITRATE ON STONE FORMATION IN HYPEROXALURIC RATS BY RADIOLUMINOGRAPHY USING ^<14>C-OXALATE

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

チトクロームP450を利用したがん原性のシュミレーションと発がんの感受性の解析

Principal Investigator

Project Period (FY)

Research Category

Research Institution

チトクロームPー450の分子生物学:発現の分子機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Effect of shock wave exposure during ESWL on renal function

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the Regulation of Thymic Hormone Secretion by Neural and Endocrine System-Using Primary Culture System of the Thymic Hormone-Secreting (Thymus Epthelial) Cells-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 生体統御システムと内分泌攪乱2005

Author(s)

Total Pages

Publisher

Description

Data Source

[Journal Article] Bisphenol A binds to Protein Disulfide Isomerase and inhibits its enzymatic and hormone-binding activities.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Inhibitory effects of environmental chemicals on protein disulfide isomerase in vitoro2005

Author(s)

Journal Title

Data Source

[Journal Article] Inhibitory effects of environmental chemicals on protein disulfide isomerase in vitro.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Bisphenol A, an environmental endocrine-disrupting chemical, inhibits hypoxic response via degradation of hypoxia-inducible factor 1alpha (HIF-1alpha): structural requirement of bisphenol A for degradation of HIF-1alpha.2004

Author(s)

Journal Title

FUNAE Yoshihiko 舩江良彦

FUNAE Yosihiko 船江良彦

HUNAE Yoshihiko 舩江良彦