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WATANABE Keiichi  渡辺 慶一

ORCIDConnect your ORCID iD *help
Researcher Number 00055865
Affiliation (based on the past Project Information) *help 1989 – 1999: Professor of Dept. of Pathology, Tokai Univ., 医学部, 教授
1993 – 1995: Tokai University School of Medicine, Professor, 医学部・病理学, 教授
1993: Tokai Univ.pathology., proffesor, school Med., 医学部・病理, 教授
1991: Prof. of Dept. of Pathology, Tokai Univ. School of Med., 医学部・病理学教室, 教授
1987 – 1989: 東海大学, 医学部・病理, 教授 … More
1987 – 1989: Professor, Department of Pathology Tokai University School of Medicine, 医学部・病理学, 教授
1988: 東海大学, 医学部(病理学), 教授
1988: 東海大学, 医学部病理学教室, 教授
1987: Department of Pathology, Tokai University School of Medicine, 医学部・(病理学), 教授
1986: 東海大, 医学部, 教授
1986: 東海大学, 医学部, 教授
1985: 東海大学, 医, 教授 Less
Review Section/Research Field
Principal Investigator
Experimental pathology
Except Principal Investigator
Digestive surgery / 細菌学 / Experimental pathology / Human pathology
Keywords
Principal Investigator
脂質過酸化 / キノリン酸 / グルタチオンペルオキシダーゼ / oxidative stress / ホルボールエステル(PMA) / Cキナーゼ(PKC) / ホルボールエステル / 過酸化ジアシルグリセロール / プロテインキナーゼC / 酸化ストレス … More / diacylglycerol / Cell Injury / Glutathione Peroxidase / Lipid Peroxidation / (GSH-POの)アミノ酸配列 / ミトコンドリア内局在 / GSH-PO合成誘導機構 / グルタチオンペルオキシダーゼ(GSH-PO)セレン(Se) / hyperplastic nodule(過形成性結節) / 蛋白合成阻害剤 / 【CCl_4】 / 脂肪肝 / 肝脂肪変性 / 細胞傷害 / グルタチオン・ペルオキシダーゼ / KOCK-OUT MICE / TISSUE NONSPECIFIC AP / EMBRYONAL AP / ALKALINE PHOSPHATASE (AP) / alkaline phophatase(AP) / knock-out mice / Tissue nonspecific AP / embryonal AP / alkaline phophatase (AP) / Resolution power in vertical and horizontal axises / CLSM for engineering / Very short wave length laser / Fine structures living cells / Confocal Laser Scanning Microscope / ヘリウム-カドニウムレーザーHe-Cd / 空間分解能 / 電顕 / 光顕 / 細胞内小器官 / 共焦点レーザー顕微鏡 / 縦軸、横軸分解能 / 工業用レーザー顕微鏡 / 紫外線領域短波長レーザー / living cellsの微細構造 / 新共焦点レーザー顕微鏡開発 / Alzheimer's disease / Phorbol ester (PMA) / Oxidized diacylglycerol / Diacylglycerol / Protein Kinase C / ホスホリパーゼC / イノシトールリン脂質 / ジアシルグリセロール / map-2 / tau / 微細管異常 / 培養神経細胞 / ホルポールエステル(PMA) / Oxidized diacylglycerol(DAG-OOH) / diacylglycerol(DAG) / Hox4B protein / homeo box gene / antigen retrieval / immunohistochemistry / in situ PCR technique / point mutation / colonic cancer in adenoma / p53 protein / heat shock protein / P^<53> / 癌抑制遺伝子 / polymerase chain reaction / 乳癌 / 胃癌 / tumor banking system / Hox4B / 抗源性賦活化 / P^<53>蛋白 / Hox4B蛋白 / ホメオティック遺伝子 / 抗原体賦活化 / 免疫組織化学 / in situ PCR法 / 点突然変異 / 大腸腺腫内癌 / p^<53>蛋白 / 泡沫細胞 / 中膜中滑筋細胞 / マクロファージ / 動脈硬化症 / ミトコンドリア内蛋白輸送 / ACTH / ステロイド産生 / ミトコンドリア内グルタチオンペルオキシダーゼ / 副腎皮質内側束状層 / signal transduction / neuronal cell death / protein kinase C / PMA / microtubule degeneration / lipid mediators / diacylglycerols / lipid peroxidation / protein kinase c isoforms / PC12細胞 / アルツハイマー病 / 過酸化ジアシルグリセロール(DAG-OOH) / ジアシルグリセロール(DAG) / 神経変性疾患 / 神経原繊維 / Cキナーゼ / 神経細胞 / ハンチントン病様病変 / グルタチオン・ペルオキシダーセ / 神経細胞壊死 / 線条体 / グルタチオン・ペルオキシダ-ゼ / グリア細胞 / 神経細胞死 / ハンチントン病 … More
Except Principal Investigator
無菌マウス / モノクローナル抗体 / GLUTATHIONE PEROXIDASE / SIGNAL TRANSDUCTION / LIPID PEROXIDATION / PROTEIN KINASE C / DIACYLGLYCEROL / glutathione peroxidase / signal transduction / lipid peroxidation / protein kinase C / diacylglycerol / Helicobacter pylori / ルミノ-ル依存性化学発光 / Kupffer細胞 / 普通マウス / ネズミチフス菌 / Ex vivo / 制癌剤 / アドリアマイシン / 細胞接着分子 / 染色体異常 / ヒトの肺 / Myeloperoxidase / Conventional mice / Germfree mice / Superoxide anion / 活性酸素 / 化学発光 / 前単球 / 顆粒球 / 粗面小胞体 / 内在性ペルオキシダ-ゼ / 肉芽腫 / 網内系 / 食細胞 / ス-パ-オキサイド / ミエロペルオキシダ-ゼ / ルンフェリン依存性化学発光 / GCRP / Calcium metabolism / Cell cycle / Secretion / Calcitonin / C cell / Thyroid Gland / 遺伝子プロセシング / 細胞内プロセシング / カルシトニン遺伝子関連ペプチド / CGRP / カルシウム代謝 / 細胞動態 / 分泌調節 / カルシトニン / C細胞 / 甲状腺 / Heterogeneity / Mosaicism / Monoclonal Antibody / モノクローナル複合体 / 治療 / 診断 / 癌 / 多相性(Heterogeneity) / モザイシズム / モノクロ-ナル抗体 / Clostridium difficile / Continuous floe culture / 細胞毒活性作用 / CF培養 / C.difficile / 連続流動培養 / oxidative stress / daicylglycerol / side effect / antibody-anti cancer drug / anti cancer drug / 薬効作用 / 副作用 / 抗制癌剤抗体 / monoclonal antibody / anti-carcinostatic / anti-ADM / ADM / ポリクローナル抗体 / 抗アドリアマイシン / 耐性 / 制癌剤抗体 / Mucosal immunity / Maltose-binding protein / Recombinant protein / Antibody-producing cells / Intestinal metaplasia / Chronic atrophic gastiritis / Enzyme-labeled antigen method / 分泌型IgA / 慢性萎縮性胃炎 / 局所免疫 / マルトース結合蛋白 / リコンビナント蛋白 / 特異抗原産生細胞 / 腸上皮化生 / 慢性萎縮性 / 酵素抗原法 / Liver and spleen / Granulomatous lesion / Facultative intracellular parasite / O_2 Production / Intestinal bacterial flora / S. typhimurium / Kupffer cell / ザイモサン / ルシフェリン依存性化学発光 / O^-_2 / PMA / クッパ-細胞 / 肉芽腫性病変 / MCLA依存性化学発光 / 普免マウス / 核DNA / 遺伝子産物 / 腺癌 / アドリアマイシン抗体 / 免疫組織化学 / 組織化学 / 基質糖蛋白 / 核DNAプロイディー / 遺伝子異常 / 線癌 Less
  • Research Projects

    (27 results)
  • Co-Researchers

    (31 People)
  •  過酸化ジアシルグリセロールの特殊なCキナーゼ活性化と神経細胞死Principal Investigator

    • Principal Investigator
      渡辺 慶一
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tokai University
  •  MOLECULAR MECHANISM FOR ALTERATION IN SIGNAL TRANSDUCTION BY OXIDATIVE STRESS -Isoform specific activation of C kinase by oxidized DAG and cell injury-

    • Principal Investigator
      TAKEKOSHI Susumu
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Tokai University
  •  酸化ジアシルグリセロールのユニークなCキナーゼ活性化作用Principal Investigator

    • Principal Investigator
      渡辺 慶一
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  MICE LACKING ALKALINE PHOSPHATASE ISOZYMES.-MOLECULAR GENETICS AND PATHOLOGICAL INVESTIGATIONPrincipal Investigator

    • Principal Investigator
      WATANABE Keiichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Experimental pathology
    • Research Institution
      TOKAI UNIVERSITY
  •  神経細胞変性・細胞死と脂質過酸化:〜酸化ジアシルグリセロールの生物学的機能と病理学的意義〜Principal Investigator

    • Principal Investigator
      渡辺 慶一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  THE STUDY OF C KINASE ACTIVATOR CAUSE FOR THE PATHOLOGICAL CHANGES.

    • Principal Investigator
      TAKEKOSHI Susumu
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      2
  •  キノリン酸による神経細胞傷害における脂質過酸化の意義Principal Investigator

    • Principal Investigator
      渡辺 慶一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  Mechanisms of Protein Kinase C Activatic by Lipid Peroxidation and its Biological SignificancePrincipal Investigator

    • Principal Investigator
      WATANABE Keiichi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Tokai university
  •  Development of a New High Performance Confocal Laser Scanning Microscpe Enabling the Observation of Dynamic Changes of Subcellular Organelles.Principal Investigator

    • Principal Investigator
      WATANABE Keiichi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Tokai University
  •  キノリン酸による神経細胞障害にみる脂質過酸化とその障害機序の究明Principal Investigator

    • Principal Investigator
      渡辺 慶一
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  A STUDY OF THE EFFECTIVENESS OF A CARCINOSTATIC AND INCREASING GARCINOSTATIC TOLERANCE

    • Principal Investigator
      MITOMI Toshio
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tokai University
  •  神経細胞の変性、壊死における脂質過酸化とその防御、修復因子の意義Principal Investigator

    • Principal Investigator
      渡辺 慶一
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  Identification of cells producing antibodies specific for Helicobacter pylori in chronic atrophic gastritis : Application of the enzyme-labeled antigen method.

    • Principal Investigator
      TSUTSUMI Yutaka
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tokai University School of Medicine
  •  A study of the effectiveness of a carcinostatic and increasing carcinostatic tolerance

    • Principal Investigator
      MITOMI Toshio
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tokai Univ.School of Medicine, Dept.surg.II
  •  キノリン酸による脂質過酸化亢進とラット線条体神経細胞の変性、壊死:脂質過酸化修復因子(グルタチオン・ペルオキシダ-ゼ)の変動による病変の修飾Principal Investigator

    • Principal Investigator
      渡辺 慶一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  DNA analysis on developmental anomalies and malignant tumors for the investigation on the mechanism of carcinogenesis.Principal Investigator

    • Principal Investigator
      WATANAVE Keiichi
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Tokai University
  •  The role of intestinal flora in qualitative change of phagocytic cell response in experimental typhoid

    • Principal Investigator
      OZAWA Atsushi
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      Department of Microbiology, Tokai University, School of Medicine
  •  ヒト肺線癌の特性の分子病理学的解析

    • Principal Investigator
      下里 幸雄
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  ヒト肺腺癌の特性の分子病理学的解析

    • Principal Investigator
      下里 幸雄
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Study of The Heterogeneity in Cancer by Monoclonal Antibodies

    • Principal Investigator
      NAKASAKI Hisao
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Department of 2nd Surgery. Tokai University, School of Medicine
  •  Synthesis and secretion of calcitonin and calcitonin gene-related peptide.

    • Principal Investigator
      KAKUDO K.
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tokai Univ, School of Medicine
  •  Salmonella typhimurium Infection and Host Resistance - With Special Reference to Nonspecific Defense Mechanisms

    • Principal Investigator
      OZAWA Atsushi
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      Tokai University, School of Medicine
  •  制癌剤の生体内局在の研究(効果増強と耐性の克服)

    • Principal Investigator
      NAKASAKI Hisao
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tokai University
  •  粥状硬化の発生,進展における中膜平滑筋細胞の脂質過酸化とその調節機構の意義Principal Investigator

    • Principal Investigator
      渡辺 慶一
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Tokai University
  •  Ecological regulation mechanism of cytotoxin activity produced by Clostridium difficile

    • Principal Investigator
      ATSUSHI OZAWA
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      Tokai University, School of Medicine
  •  Cytosolic Proteinの膜通過調節機構に関する研究Principal Investigator

    • Principal Investigator
      渡辺 慶一
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Tokai University
  •  Pathogenetic Significance of Lipid Peroxidation in Various Cell Injuries, with a Special Reference to the Investigation on Cell Biological Characteristics of Glutathione Peroxidase-an Anti-lipoperoxidative Agent.Principal Investigator

    • Principal Investigator
      WATANABE Keiichi
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Tokai University
  • 1.  TAKEKOSHI Susumu (70216878)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  YAMAMOTO Yorihiro (60134475)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  MORIUCHI Tetsuya (20174394)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  NAKASAKI Hisao (10056145)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  OZAWA Atsushi (50055638)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  OHNISHI Nobuhiko (30051717)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  TSUTSUMI Yutaka (80138643)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  OSAMURA Yoshiyuki (10100992)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  MITOMI Toshio (20055809)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  吉村 慎一 (30230808)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  下里 幸雄 (10076979)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  関口 清俊 (50187845)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  浜田 新七 (00172974)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  桜井 雅温 (20025604)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  横田 淳 (10191503)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  松島 一士 (70209542)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  瀧沢 俊也 (70197234)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  SATO Shinkichi (80119677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  WAKAKI Moriaki (20100993)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  YOKOYAMA Seihichi (50096278)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  MATSUZAKI shouhei (40110902)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  TOKUDA Yutaka (20163975)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  KAKUDO K. (00112037)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  渋谷 誠 (50201546)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  森 一郎 (10157852)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  NABER Stephan p.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  WOLFE Hubert j.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  NARISAWA Sonoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  MILLAN Jose Luis
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  STEPHAN P.Na
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  HUBERT J.Wol
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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