TAKEKOSHI Susumu 竹腰進

Researcher Number	70216878
Other IDs
External Links
Affiliation (Current)	2020: 東海大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2018: 東海大学, 医学部, 教授 2006 – 2014: 東海大学, 医学部, 准教授 2012: 東海大学, 医学部・病態病理学, 准教授 2007: Tokai University, 医学部・健康科学部, 准教授 2004 – 2006: 東海大学, 医学部, 助教授 … More
Review Section/Research Field	Principal Investigator Experimental pathology / Experimental pathology Except Principal Investigator Human pathology / Human pathology / Cerebral neurosurgery / Experimental pathology / Anesthesiology/Resuscitation studies / Digestive surgery / Experimental pathology / Dermatology … More
Keywords	Principal Investigator diacylglycerol / lipid peroxidation / oxidative stress / protein kinase C / signal transduction / MAP kinase / neuron / glutathione peroxidase / brain / 脂質過酸化 … More Except Principal Investigator 転写因子 / 下垂体 / Pit-1 / 免疫組織化学 / キノリン酸 / 下垂体細胞 / 脂質過酸化 / 酸化ストレス / 乳癌 / E2F-5 / Immunohistochemistry / 下垂体腺腫 / mRNA / 成長ホルモン / TSH / in situ hybridization / rab3B / 神経細胞 / diacylglycerol / プロテインキナーゼC / 過酸化ジアシルグリセロール / グルタチオンペルオキシダーゼ / ホルボールエステル / Cキナーゼ(PKC) / ホルボールエステル(PMA) / oxidative stress / 前立腺癌 / ホルモン治療 / 細胞増殖 / 活性酸素 / 腫瘍 / PTTG / トランスジェニックマウス / breast cancer / 分泌顆粒 / pit-1遺伝子 / Pituitary gland / growth hormone / レセプター / glioma / immunohistochemistry / GATA2 / DU-PAN-2 / CA19-9 / nitric oxide / PAI-1 / αSU / FOXL2 / GFP / chromogranin A / secretogranin 3 / carboxypeptidase E / phogrin / pituitary cell / 神経回路 / マイクロCT / マイクロトモグラフィ / ハンチントン病 / 神経細胞死 / グリア細胞 / グルタチオン・ペルオキシダ-ゼ / 線条体 / 神経細胞壊死 / グルタチオン・ペルオキシダーセ / ハンチントン病様病変 / Cキナーゼ / 神経原繊維 / 神経変性疾患 / ジアシルグリセロール(DAG) / 過酸化ジアシルグリセロール(DAG-OOH) / アルツハイマー病 / PC12細胞 / protein kinase c isoforms / lipid peroxidation / diacylglycerols / lipid mediators / microtubule degeneration / PMA / protein kinase C / neuronal cell death / signal transduction / チロシンキナーゼ受容体 / ホルモン受容体 / Quantum dots / in vivo / confocal microscopy / spectrum analysis / 薬剤感受性 / 細胞内蛋白相互作用 / エストロジェンレセプター(ER) / ヒト乳がん細胞培養株(BT474) / スペクトル解析 / CLSM / Human Epidermal Growth Factor Receptor(HER2) / 細胞内情報伝達 / 揮発性麻酔薬 / セボフルレン / MAP kinase / PKC / 脂肪酸代謝障害 / 脂肪酸運送タンパク(FABP) / 抗体療法 / ER陰性 / HER2陰性 / estrogen receptor / human epidermal growth factor receptor-2 / 転写因子 E2F-5 / triple negative breast cancer / basal phenotype / Estrogen receptor / HER2 / リン酸化Akt / 化学発癌 / 疫学 / 胆嚢癌 / 重金属 / 癌疫学 / Notchシグナル / Wntシグナル / Anterior Pituitary / Pitutary Adenoma / NOTCH receptor / Wnt signaling / Translocation / Pituitary Adenoma / NOTCH ligand / Cell to cell interaction / Anterior Pituitar / Ecdysone System / 遺伝子変異多様性 / クロナリティー / ミトコンドリアDNA D-loop領域 / clonality / androgen receptor polymorphism / mitochondria DNA / クロナリティー解析 / MtDNA D-loop / クロナリティ / androgen receptor遺伝子多型 / 原発巣 / 再発巣 / 皮膚病理学 / 乾癬 / 増殖・分化異常 / MAPキナーゼ / 幹細胞マーカー / シグナル伝達 / 慢性炎症性皮膚疾患 / ヒト皮膚組織 / 紫外線 / 抗酸化酵素 / レーザーマイクロダイセクション / FSHβ / LHβ / DNAメチル化 / CpG / エピジェネティクス / LH / ゴナドトロフ / ソマトスタチン / ACTH / C細胞 / 甲状腺 / 細胞分化 / 腫瘍分化 / 分泌 / ホルモン合成 / ライソソ-ム / C cell / Thyroid / Cell differentiation / Tumor differentiation / Secretion / Hormone synthesis / Lysosome / transcriptional factor / 免疫組織科学 / 転写促進因子 / 下垂体腺腫過形成 / factor growth hormone releasing(GRF) / アクロメガリー / プロラクチン / 甲状腺刺激ホルモン / adenoma / prolactin / Transgenic animal / 下垂体前葉細胞 / 機能分化 / in situ hyhridization / in situ PCR / 機能発現 / 遺伝子発現 / ホルモンレセプター / Pit-1遺伝子 / Receptor / In situ hydridization / In situ PCR / diacylglycerol(DAG) / Oxidized diacylglycerol(DAG-OOH) / ホルポールエステル(PMA) / 培養神経細胞 / 微細管異常 / tau / map-2 / ジアシルグリセロール / イノシトールリン脂質 / ホスホリパーゼC / Protein Kinase C / Diacylglycerol / Oxidized diacylglycerol / Phorbol ester (PMA) / Alzheimer's disease / p16 / proliferation / FISH / FLSH / 神経膠腫 / 増殖能 / p16 gene / proliferative potential / fluorescence in situ hybridization / alkaline phophatase (AP) / embryonal AP / Tissue nonspecific AP / knock-out mice / alkaline phophatase(AP) / ALKALINE PHOSPHATASE (AP) / EMBRYONAL AP / TISSUE NONSPECIFIC AP / KOCK-OUT MICE / ヒト下垂体 / human pituitary / transcription factor / receptor / 授乳期乳腺 / magentosis / 細胞死 / 一本鎖DNA / マウスモデル / poly(ADP-ribose) / PAS染色 / 甲状腺乳頭癌 / 離乳 / 実験モデル(ラット) / ポリADPリボース / アポトーシス / lactating breast / magntosis / cell death / single-stranded DNA / mouse model / poly (ADP-ribose) / PAS staining / thyroid papillary carcinoma / ゴナドトロピン / RT-PCR / GATA-2 / pituitary cells / pituitary adenomas / gonadotropin / transcription factors / 子宮体癌 / 糖鎖 / 体癌 / 1型糖鎖 / 腫瘍マーカー / endometrial adenocarcinoma / carbohydrate antigen / レドックス / 心・血管系 / Redox / Cardiovascular system / Reactive oxygen species (ROS) / ER陰性・HER2陰性乳癌 / 細胞周期関連蛋白 / エストロゲンレセプター / human epidermal growth factor receptor / ER-negative / HER2-negative / cell proliferation / Ki-67 / 下垂体前葉ホルモン / Pit1 / CDKインヒビター / サンドスタチンレセプター / αサブユニット / Pituitary / Adenoma / Growth hormone / secretory granule / モータープロテイン / キネシンスーパーファミリー / 細胞内輸送 / 脳・神経 / 蛋白質 / motor protein / kinesin superfamily / intracellular transport / 選択的スプライシング / RNA結合タンパク質 / 3'UTR / 神経科学 / 発現制御 / 脳神経疾患 / ナノトモグラフィ / 統合失調症 / 脳 / 三次元構造 / 放射光 / nanotomography / nano-CT / トモグラフィ Less

脂溶性情報伝達分子の脂質過酸化反応を起点とする肝線維化の分子機構の解析Principal InvestigatorOngoing
- Principal Investigator
  
  竹腰進
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokai University
The RNA-based mechanism and function underlying molecular diversity in the nervous system
- Principal Investigator
  
  IIJIMA Takatoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokai University
Computerized model building of brain neuronal network
- Principal Investigator
  
  Mizutani Ryuta
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological physics/Chemical physics/Soft matter physics
- Research Institution
  Tokai University
Analysis of cerebral network in psychiatric disease cases
- Principal Investigator
  
  MIZUTANI Ryuta
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Brain biometrics
- Research Institution
  Tokai University
Analysis of molecular mechanism of oxidative stress regulation by RNA splicingPrincipal Investigator
- Principal Investigator
  
  TAKEKOSHI Susumu
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokai University
Identification of molecules affecting ACTH secretion and establishment of novel therapy of pituitary adenomas
- Principal Investigator
  
  MATSUNO AKIRA
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
Fundamental research on target therapies for hormone-resistant prostate cancer
- Principal Investigator
  
  TANG Xiaoyan
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Nihon University
  Tokai University
A clonality analysis of breast cancer tissue with heterogenity : clarifying the cell lineage for adequate treatment strategy for recurrent tumor
- Principal Investigator
  
  MASUDA Shinobu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Nihon University
  Tokai University
Signaling in response to oxidative stress disorder caused by ultraviolet
- Principal Investigator
  
  OZAWA Akira
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Tokai University
下垂体ゴナドトロピン産生細胞および腫瘍における可塑的機能分化
- Principal Investigator
  
  井野元智恵, 長村義之
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Tokai University
Molecular mechanisms of particular defense system against oxidative stress induced by the control of signalingPrincipal Investigator
- Principal Investigator
  
  TAKEKOSHI Susumu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokai University
Molecular pathology for functional differentiation of human pituitary adenomas : New development of NOTCH signaling pathway.
- Principal Investigator
  
  OSAMURA Yoshiyuki
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Tokai University
下垂体腫瘍形質転換遺伝子(PTTG)の時期特異的発現と腫瘍形成機構の解明
- Principal Investigator
  
  梶谷華子
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Tokai University
A analysis for the cell proliferation mechanisms of hormone independent breast cancers. ERnegative and HER2 negative breast cancers and transcriptional factors
- Principal Investigator
  
  UMEMURA Shinobu
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokai University
化学発癌が疑われるインドの胆嚢癌の発生機序の解明と早期診断に関する国際共同研究
- Principal Investigator
  
  小田高司
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya University
Analysis of regulatory mechanism for signal transduction responding to oxidative stressPrincipal Investigator
- Principal Investigator
  
  TAKEKOSHI Susumu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokai University
Study on role of motor proteins in intracellular transport of pituitary hormone
- Principal Investigator
  
  MATSUNO Akira
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
脂肪酸代謝障害による前立腺癌の増殖抑制効果:創薬への基盤的研究
- Principal Investigator
  
  TANG Xiaoyan
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Tokai University
ナノクリスタルQuantum(Q)dotsの免疫組織化学への応用
- Principal Investigator
  
  OSAMURA Yoshiyuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Tokai University
揮発性麻酔薬の細胞内情報伝達系に及ぼす影響
- Principal Investigator
  
  鈴木利保
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Tokai University
Molecular pathology of the functional differentiation of the pituitary adenoma
- Principal Investigator
  
  OSAMURA Yoshiyuki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Tokai University
Search for novel molecule response to oxidative stressPrincipal Investigator
- Principal Investigator
  
  TAKEKOSHI Susumu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokai University
Study on the molecular mechanism of secretory granule formation of pituitary hormone
- Principal Investigator
  
  MATSUNO Akira
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
Redox-regulation by active oxygen species / nitric oxide in cardiovascular system
- Principal Investigator
  
  NAKAZAWA Hiroe
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Tokai University
Biological characteristics of hormone independent (ER-negative/HER2-negative) breast cancers.
- Principal Investigator
  
  UMEMURA Shinobu
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokai University
Clinicopathological and functional analysis of carbohydrate antigen expression : Focusing on DU-PAN-2 (precursor of CA19-9)
- Principal Investigator
  
  YASUDA Masanori
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokai University
The mechanisms for the alteration of intercellular signaling and the neuronal cell injury by oxidative stressPrincipal Investigator
- Principal Investigator
  
  SUSUMU Takekoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokai University
Molecular Mechanisms for Functional Differentiation of Pituitary Cells and Pituitary Adenomas
- Principal Investigator
  
  OSAMURA yoshiyuki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Tokai University
Sepecific activation of PKC by lipid peroxidation and the mechanism of cell injuryPrincipal Investigator
- Principal Investigator
  
  TAKAEKOSHI Susumu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokai University
過酸化ジアシルグリセロールの特殊なCキナーゼ活性化と神経細胞死
- Principal Investigator
  
  渡辺慶一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokai University
The significance of polyADP ribosylation in 'magentosis', a new type of cell death: Molecular pathologic approaches to magentosis in a regressing stage of human lactating breast and other hormone-responsive organs
- Principal Investigator
  
  TSUTSUMI Yutaka
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokai University
MOLECULAR MECHANISM FOR ALTERATION IN SIGNAL TRANSDUCTION BY OXIDATIVE STRESS -Isoform specific activation of C kinase by oxidized DAG and cell injury-Principal Investigator
- Principal Investigator
  
  TAKEKOSHI Susumu
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokai University
酸化ジアシルグリセロールのユニークなCキナーゼ活性化作用
- Principal Investigator
  
  渡辺慶一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
MICE LACKING ALKALINE PHOSPHATASE ISOZYMES.-MOLECULAR GENETICS AND PATHOLOGICAL INVESTIGATION
- Principal Investigator
  
  WATANABE Keiichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Experimental pathology
- Research Institution
  TOKAI UNIVERSITY
Molecular mechanism of transcription factor and receptors on the pituitary glands and pituitary adenomas
- Principal Investigator
  
  OSAMURA Yoshiyuki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Tokai University
神経細胞変性・細胞死と脂質過酸化:〜酸化ジアシルグリセロールの生物学的機能と病理学的意義〜
- Principal Investigator
  
  渡辺慶一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
p16 gene alteration and proliferative potential of gliomas with fluorescence in situ hybridization and immunohistochemical studies.
- Principal Investigator
  
  SHIBUYA Makoto
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokai University, School of Medicine
THE STUDY OF C KINASE ACTIVATOR CAUSE FOR THE PATHOLOGICAL CHANGES.Principal Investigator
- Principal Investigator
  
  TAKEKOSHI Susumu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  2
キノリン酸による神経細胞傷害における脂質過酸化の意義
- Principal Investigator
  
  渡辺慶一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
酸化ストレスによる抗酸化酵素のミトコンドリア内への移入促進作用の解析Principal Investigator
- Principal Investigator
  
  竹腰進
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokai University
Morphologic studies
- Principal Investigator
  
  OSAMURA Yoshiyuki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Tokai University School of Medicine
Mechanisms of Protein Kinase C Activatic by Lipid Peroxidation and its Biological Significance
- Principal Investigator
  
  WATANABE Keiichi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokai university
キノリン酸による神経細胞障害にみる脂質過酸化とその障害機序の究明
- Principal Investigator
  
  渡辺慶一
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
過酸化脂質によるグルタチオンペルオキシダーゼの合成促進作用の解析Principal Investigator
- Principal Investigator
  
  竹腰進
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokai University
熱ショック蛋白質による脂質過酸化防御酵素のミトコンドリア内局在化促進作用の解析Principal Investigator
- Principal Investigator
  
  竹腰進
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokai University
神経細胞の変性、壊死における脂質過酸化とその防御、修復因子の意義
- Principal Investigator
  
  渡辺慶一
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
Immunohistochemical expression of Pit-1/GHF-1 in pituitary adenomas in human and in transgenic animals
- Principal Investigator
  
  OSAMURA Yoshiyuki
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Tokai University
キノリン酸による脂質過酸化亢進とラット線条体神経細胞の変性、壊死:脂質過酸化修復因子(グルタチオン・ペルオキシダ-ゼ)の変動による病変の修飾
- Principal Investigator
  
  WATANABE Keiichi
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
Induction of thyroid C cell function and its mechanism.
- Principal Investigator
  
  KAKUDO K.
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Wakayama Medical College

[Book] 細胞2010
- Author(s)
  竹腰進, 他
- Publisher
  レーザーマイクロダイセクション法を用いた分子病理学的解析
- Data Source
  KAKENHI-PROJECT-20590385
[Book] Unveiling 3D Biological Structures by X-ray Microtomography Microscopy : Science, Technology, Applications and Education2010
- Author(s)
  R.Mizutani, A.Takeuchi, K.Uesugi, S.Takekoshi, R.Y.Osamura, Y.Suzuki
- Data Source
  KAKENHI-PROJECT-20590385
[Book] レーザーマイクロダイセクション法を用いた分子病理学的解析(細胞Vol.42 No.2)2010
- Author(s)
  竹腰進、平林華子、江頭登、梅村しのぶ、長村義之
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-20590385
[Book] Three-dimensional microstructural analysis of human brain tissues by using synchrotron radiation microtomographs.(Editor : T.B.Westland, R.N.Calton)2009
- Author(s)
  Ryuta Mizutani, Akihisa Takeuchi, Kentaro Uesugi, Susumu Takekoshi, R.Yoshiyuki Osamura, Yoshio Suzuki
- Publisher
  Handbook on White Matter
- Data Source
  KAKENHI-PROJECT-20590385
[Book] 組織細胞化学20072007
- Author(s)
  竹腰進
- Publisher
  レーザーマイクロダイセクションと病理診断
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590381
[Book] J Histochemistry Cytochemistry2007
- Author(s)
  Inomoto C., Takekoshi S., et al.
- Publisher
  Granulogenesis in non-neuroendocrine COS-7 Cell induced by EGFP-tagged Chromogranin A Gene Transfection (In press)
- Data Source
  KAKENHI-PROJECT-18590381
[Journal Article] Immunolocalization of Glutathione-Peroxidase(GPx1), Androgen Receptor(AR), 5alpha-Reductase Type I and Type II in Steroid Hormone-Induced Rat Prostatic Hyperplasmic and Canine Spontaneous Prostatic Hyperplasia-Atrophic Effec of Chlormadinone Acetate(CMA) on Rat- and Canine-Prostatic Hyperplasia Models.2019
- Author(s)
  Murakoshi M, Takekoshi S.
- Journal Title
  
  Pharmacometrics
  
  Volume: 96 Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08721
[Journal Article] Three-dimensional alteration of neurites in schizophrenia.2019
- Author(s)
  Mizutani R, Saiga R, Takeuchi A, Uesugi K, Terada Y, Suzuki Y, De Andrade V, De Carlo F, Takekoshi S, Inomoto C, Nakamura N, Kushima I, Iritani S, Ozaki N, Ide S, Ikeda K, Oshima K, Itokawa M, Arai M.
- Journal Title
  
  Transl Psychiatry
  
  Volume: 9 Pages: 1-12
- DOI
  10.1038/s41398-019-0427-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08721, KAKENHI-PROJECT-17H04324, KAKENHI-PROJECT-16K15565
[Journal Article] Presence of human herpes virus 1-thymidine kinase in testis of azoospermic infertile herpes-infected patients.2018
- Author(s)
  Chen M, Cai LY, Yoshida S, Takekoshi S, Kajiwara H, Nishimura N, Wang H, Kato T, Izumi S, Kato Y.
- Journal Title
  
  Reprod Toxicol.
  
  Volume: 82 Pages: 57-62
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08721
[Journal Article] Determination of triacylglycerol oxidation mechanisms in canola oil using liquid chromatography?tandem mass spectrometry2018
- Author(s)
  Kato S, Shimizu N, Hanzawa Y, Otoki Y, Ito J, Kimura F, Takekoshi S, Sakaino M, Sano T, Eitsuka T, Miyazawa T, Nakagawa K.
- Journal Title
  
  npj Sci. of Food
  
  Volume: - Pages: 1-1
- DOI
  10.1038/s41538-017-0009-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08721, KAKENHI-PROJECT-15H04497
[Journal Article] Pathophysiological characteristics of non-alcoholic steatohepatitis-like changes in cholesterol-loaded type 2 diabetic rats.2018
- Author(s)
  Toriniwa Y, Muramatsu M, Ishii Y, Riya E, Miyajima K, Ohshida S, Kitatani K, Takekoshi S, Matsui T, Kume S, Yamada T, Ohta T.
- Journal Title
  
  Physiol Res.
  
  Volume: 67 Pages: 601-612
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08721
[Journal Article] Liposome-encapsulated hemoglobin ameliorates skin wound healing in diabetic dB/dB mice.2017
- Author(s)
  Ｆｕｋｕｉ T, Kawaguchi AT, Takekoshi S, Miyasaka M, Sumiyoshi H, Tanaka R.
- Journal Title
  
  Artif Organs.
  
  Volume: 41(4) Pages: 319-326
- DOI
  10.1111/aor.12864
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10071, KAKENHI-PROJECT-16K08721, KAKENHI-PROJECT-15H02569
[Journal Article] Estimating the resolution of real images2017
- Author(s)
  Mizutani R、Saiga R、Takekoshi S、Inomoto C、Nakamura N、Arai M、Oshima K、Itokawa M、Takeuchi A、Uesugi K、Terada Y、Suzuki Y
- Journal Title
  
  J. Phys. Conf. Ser.
  
  Volume: 849 Pages: 012042-012042
- DOI
  10.1088/1742-6596/849/1/012042
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25282250
[Journal Article] Estimating the resolution of real images2017
- Author(s)
  Ryuta Mizutani, Rino Saiga, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Makoto Arai, Kenichi Oshima, Masanari Itokawa, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada and Yoshio Suzuki
- Journal Title
  
  AIP Conference Proceedings
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25282250
[Journal Article] Spatio-temporal and dynamic regulation of neurofascin alternative splicing in mouse cerebellar neurons.2017
- Author(s)
  Suzuki S, Ayukawa N, Okada C, Tanaka M, Takekoshi S, Iijima Y, Iijima T.
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Pages: 11405-11405
- DOI
  10.1038/s41598-017-11319-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08721, KAKENHI-PROJECT-15H04277, KAKENHI-PROJECT-15K14355
[Journal Article] Cartilage Oligomeric Matrix Protein Increases in Photodamaged Skin2016
- Author(s)
  Kobayashi M, Kawabata K, Kusaka-Kikushima A, Sugiyama Y, Mabuchi T, Takekoshi S, Miyasaka M, Ozawa A, Sakai S.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: 136 Pages: 1143-1149
- DOI
  10.1016/j.jid.2016.02.802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08721
[Journal Article] A method for estimating spatial resolution of real image in the Fourier domain2016
- Author(s)
  Mizutani R, Saiga R, Takekoshi S, Inomoto C, Nakamura N, Itokawa M et al.
- Journal Title
  
  J. Microsc.
  
  Volume: 261 Pages: 57-66
- DOI
  10.1111/jmi.12315
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25253074, KAKENHI-PROJECT-24590464, KAKENHI-PROJECT-25610126, KAKENHI-PROJECT-25282250
[Journal Article] Effect of Scavenging Circulating Reactive Carbonyls by Oral Pyridoxamine in Uremic Rats on Peritoneal Dialysis2016
- Author(s)
  Mori Y, Kakuta T, Miyakogawa T, Takekoshi S, Yuzawa H, Kobayashi H, Kawakami A, Miyata T, Fukagawa M.
- Journal Title
  
  Ther Apher Dial.
  
  Volume: 20 Pages: 645-654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08721
[Journal Article] Three-dimensional structure of brain tissue at submicrometer resolution2016
- Author(s)
  Rino Saiga, Ryuta Mizutani, Chie Inomoto, Susumu Takekoshi, Naoya Nakamura, Akio Tsuboi, Motoki Osawa, Makoto Arai, Kenichi Oshima, Masanari Itokawa, Kentaro Uesugi, Akihisa Takeuchi, Yasuko Terada, and Yoshio Suzuki
- Journal Title
  
  AIP Conf. Proc.
  
  Volume: 1696 Pages: 020004-020004
- DOI
  10.1063/1.4937498
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25610126, KAKENHI-PROJECT-25282250
[Journal Article] Notch Signaling May Be Involved in the Abnormal Differentiation of Epidermal Keratinocytes in Psoriasis2015
- Author(s)
  Horikoshi Y, Kitatani K, Toriumi K, Fukunishi N, Itoh Y, Nakamura N, Ohno S, Matsura T, Takekoshi S.
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 85 Issue: 4 Pages: 175-183
- DOI
  10.1267/ahc.14027
- NAID
  130004677405
- ISSN
  0044-5991, 1347-5800
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590464
[Journal Article] Scanning Brain Networks with Micro-CT2015
- Author(s)
  Ryuta Mizutani, Rino Saiga, Susumu Takekoshi, Makoto Arai, Akihisa Takeuchi, and Yoshio Suzuki
- Journal Title
  
  Microscopy Today
  
  Volume: 23 Pages: 12-17
- DOI
  10.1017/s1551929515000784
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25610126, KAKENHI-PROJECT-25282250
[Journal Article] Aberrant Activation of Atypical Protein Kinase C in Carbon Tetrachloride-Induced Oxidative Stress Provokes a Disturbance of Cell Polarity and Sealing of Bile Canalicular Lumen.2015
- Author(s)
  Horikoshi Y, Kitatani K, Toriumi K, Fukunishi N, Itoh Y, Nakamura N, Ohno S, Matsura T, Takekoshi S.
- Journal Title
  
  American Journal of Pathology
  
  Volume: 85 Pages: 958-968
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590464
[Journal Article] Reduced Expression of Hugl 1 Contributes to the Progression of Lung Squamous Cell Carcinoma.2015
- Author(s)
  Matsuzaki T, Takekoshi S, Toriumi K, Kitatani K, Nitou M, Imamura N, Ogura G, Masuda R, Nakamura N, Iwazaki M.
- Journal Title
  
  Tokai J Exp Clin Med.
  
  Volume: 40 Pages: 169-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590464
[Journal Article] Three-dimensional neuronal structure of human cerebral cortex determined by synchrotron-radiation microtomography2015
- Author(s)
  Saiga R, Takekoshi S, Inomoto C, Nakamura N, Tsuboi A, Osawa M, Arai M, Oshima K, Itokawa M, Uesugi K, Takeuchi A, Terada Y, Suzuki Y and Mizutani R.
- Journal Title
  
  Microsc. Microanal.
  
  Volume: 21 Pages: 919-920
- DOI
  10.1017/s1431927615005395
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25253074, KAKENHI-PROJECT-25610126, KAKENHI-PROJECT-25282250
[Journal Article] Stimulation of melanogenesis by nordihydroguaiaretic acid in human melanoma cells.2014
- Author(s)
  Takekoshi S, Nagata H, Kitatani K.
- Journal Title
  
  Acta Histochemca Cytochemica
  
  Volume: 47 Pages: 203-210
- NAID
  130004687242
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590464
[Journal Article] Roles of oxidized diacylglycerol for carbon tetrachloride-induced liver injury and fibrosis in mouse.2014
- Author(s)
  Takekoshi S, Kitatani K, Yamamoto Y.
- Journal Title
  
  Acta Histochemca Cytochemica
  
  Volume: 47 Pages: 185-194
- NAID
  130004687241
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590464
[Journal Article] Carbon tetrachloride-induced hepatic injury through formation of oxidized diacylglycerol and activation of the PKC/NF-κB pathway.2013
- Author(s)
  Toriumi K, Horikoshi Y, Yoshiyuki Osamura R, Yamamoto Y, Nakamura N, Takekoshi S.
- Journal Title
  
  Laboratory Investigation
  
  Volume: 93 Pages: 218-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590464
[Journal Article] Localization of aPKC Lambda/Iota and Its Interacting Protein, Lgl2, Is Significantly Associated with Lung Adenocarcinoma Progression.2013
- Author(s)
  Imamura N, Horikoshi Y, Matsuzaki T, Toriumi K, Kitatani K, Ogura G, Masuda R, Nakamura N, Takekoshi S, Iwazaki M
- Journal Title
  
  Tokai J Exp Clin Med.
  
  Volume: 38 Pages: 146-158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590464
[Journal Article] Over-expression of BACH2 is related to ongoing somatic hypermutation of the immunoglobulin heavy chain gene variable region of de novo diffuse large B-cell lymphoma.2013
- Author(s)
  Kikuchi T, Tokunaka M, Kikuti YY, Carreras J, Ogura G, Takekoshi S, Kojima M, Ando K, Hashimoto Y, Abe M, Takata K, Yoshino T, Muto A, Igarashi K, Nakamura N.
- Journal Title
  
  Pathol Int.
  
  Volume: 63 Pages: 339-344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590464
[Journal Article] uercetin stimulates melanogenesis in hair follicle melanocyte of the mouse.2013
- Author(s)
  Takekoshi S, Matsuzaki K, Kitatani K.
- Journal Title
  
  Tokai J Exp Clin Med.
  
  Volume: 38 Pages: 124-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590464
[Journal Article] Molecular morphology of pituitary cells, from conventional immunohistochemistry to fluorescein imaging2011
- Author(s)
  Matsuno A, Mizutani A, Okinaga H, Takano K, Yamada S, Yamada SM, Nakaguchi H, Hoya K, Murakami M, Takeuchi M, Sugaya M, Itoh J, Takekoshi S, Osamura RY
- Journal Title
  
  Molecules
  
  Volume: 16 Pages: 3618-3635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592143
[Journal Article] Molecular morphology of pituitary cells, from conventional immunohistochemistry to fluorescence imaging2011
- Author(s)
  Matsuno A, Mizutani A, Okinaga H, Takano K, Yamada S, Yamada SM, Nakaguchi H, Hoya K, Murakami M, Takeuchi M, Sugaya M, Itoh J, Takekoshi S, Osamura RY
- Journal Title
  
  Molecules
  
  Volume: 16 Pages: 3618-3635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592143
[Journal Article] Molecular morphological research of anterior pituitary hormone production, intracellular transport and secretion2011
- Author(s)
  Matsuno A, Mizutani A, Okinaga H, Takano K, Yamada S, Yamada SM, Nakaguchi H, Hoya K, Murakami M, Takeuchi M, Sugaya M, Itoh J, Takekoshi S, Osamura RY
- Journal Title
  
  Trends in Cell and Molecular Biology
  
  Volume: 6 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592143
[Journal Article] Functional molecular morphology of anterior pituitary cells, from hormone production to intracellular transport and secretion2011
- Author(s)
  Matsuno A, Mizutani A, Okinaga H, Takano K, Yamada S, Yamada SM, Nakaguchi H, Hoya K, Murakami M, Takeuchi M, Sugaya M, Itoh J, Takekoshi S, Osamura RY
- Journal Title
  
  Med Mol Morphol
  
  Volume: 44 Pages: 63-70
- NAID
  10029036664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592143
[Journal Article] Somatostatin analogue inhibits the mobility of prostate carcinoma cells: A new therapeutic method for advanced prostate carcinoma.2010
- Author(s)
  Tang XY, Takekoshi S, Itoh J, Umemura S, Shoji S, Terachi T, Osamura RY
- Journal Title
  
  International Journal of Oncology
  
  Volume: 37 Pages: 1077-1083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590320
[Journal Article] Protein oxidative damage and heme oxygenase in sunlight exposed human skin : Role of MAPK responses to oxidative stress.2010
- Author(s)
  Emiko Akasaka, Susumu Takekoshi, Yosuke Horikoshi, Kentarou Toriumi, Muneo Miyasaka, Akira Ozawa
- Journal Title
  
  Tokai Journal Experimental Medicine 35
  
  Pages: 152-164
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] High expression of thymidine phosphorylase in basal-like breast cancers : Stromal expression in EGFR- and/or CK5/6-positive breast cancers.2010
- Author(s)
  S.Umemura, S.Takekoshi, et al.
- Journal Title
  
  Oncogene Letters
  
  Volume: 1 Pages: 261-266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic mice.2010
- Author(s)
  C.Doi, S.Takekoshi, et al.
- Journal Title
  
  BMC Cancer
  
  Volume: 10 Pages: 67-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Submicrometer tomographic resolution examined using a micro-fabricated test object.2010
- Author(s)
  Mizutani R., Takekoshi S., et al
- Journal Title
  
  Micron 41
  
  Pages: 90-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Microtomographic Analysis of Neuronal Circuits of Human Brain.2010
- Author(s)
  Ryuta Mizutani, Akihisa Takeuchi, Kentaro Uesugi, Yoshiyuki Osamura, Susumu Takekoshi, Yoshio Suzuki
- Journal Title
  
  Cerebral Cortex 20
  
  Pages: 1739-1748
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Hypophysectomy for a Dog with Coexisting Cushing's Disease and Diabetes Mellitus.2010
- Author(s)
  H.Ishino, S.Takekoshi, et al.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 3 Pages: 343-348
- NAID
  130000134538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] High expression of thymidine phosphorylase in basal-like breast cancers : stromal expression in EGFR positive, CK5/6 positive breast cancers2010
- Author(s)
  Umemura S, Shirane M, Takekoshi S, Tokuda Y, Mori K, Osamura RY
- Journal Title
  
  Oncology Letters
  
  Volume: 1 Pages: 261-266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590387
[Journal Article] Submicrometer tomographic resolution examined using a micro-fabricated test object2010
- Author(s)
  Ryuta Mizutani, Akihisa Takeuchi, Yoshiyuki Osamura, Susumu Takekoshi, Kentaro Uesugi, Yoshio Suzuki
- Journal Title
  
  Micron 41
  
  Pages: 90-95
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Inhibitory Effects of Anti-VEGF Antibody on the Growth and Angiogenesis of Estrogen-induced Pituitary Prolactinoma in Fischer 344 Rats2010
- Author(s)
  K.Miyajima, S.Takekoshi, et al.
- Journal Title
  
  Acta Histochemca Cytochemica
  
  Volume: 43 Pages: 33-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Submicrometer tomographic resolution examined using a micro-fabricated test object.2010
- Author(s)
  R.Mizutani, S.Takekoshi, et al.
- Journal Title
  
  Micron
  
  Volume: 41 Pages: 90-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Somatostatin analogue inhibits the mobility of prostate carcinoma cells : a new therapeutic method for advanced prostate carcinoma.2010
- Author(s)
  Xiaoyan Tang, Susumu Takekoshi, Johbu Itoh, Shinobu Umemura, Sunao Shoji, Robert Yoshiyuki Osamura
- Journal Title
  
  Int J Oncol 37
  
  Pages: 1077-1083
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Somatostatin analogue inhibits the mobility of prostate carcinoma cells : A new therapeutic method for advanced prostate carcinoma2010
- Author(s)
  Tang X, Takekoshi S, Shinobu U, Terachi T
- Journal Title
  
  INTERNATIONAL JOURNAL OF ONCOLOGY
  
  Volume: 37 Pages: 1077-1083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590320
[Journal Article] Microtomographic Analysis of Neuronal Circuits of Human Brain.2010
- Author(s)
  R.Mizutani, S.Takekoshi, et al.
- Journal Title
  
  Cerebral Cortex
  
  Volume: 20 Pages: 1739-1748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Protein oxidative damage and heme oxygenase in sunlight-exposed human skin : roles of MAPK responses to oxidative stress2010
- Author(s)
  Akasaka E, Takekoshi S, Horikoshi Y, Toriumi K, Ikoma N, Mabuchi T, Tamiya S, Matsuyama T, Ozawa A
- Journal Title
  
  Tokai J Exp Clin Med
  
  Volume: Vol.35、No.4 Pages: 152-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591446
[Journal Article] Somatostatin analogue inhibits the mobility of prostate carcinoma cells : a new therapeutic method for advanced prostate carcinoma.2010
- Author(s)
  X.Tang, Takekoshi, et al.
- Journal Title
  
  Int J Oncol
  
  Volume: 37 Pages: 1077-1083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Inhibitory Effects of Anti-VEGF Antibody on the Growth and Angiogenesis of Estrogen-induced Pituitary Prolactinoma in Fischer 344 Rats : Animal Model of VEGF-targeted Therapy for Human Endocrine Tumors.2010
- Author(s)
  Katsuhiro Miyajima, Susumu Takekoshi, Johbu Itoh, Kochi Kakimoto, Takashi Miyakoshi, Robert Yoshiyuki Osamura
- Journal Title
  
  Acta Histochemca Cytochemica 43
  
  Pages: 33-44
- NAID
  130000248640
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Somatostatin analogue inhibits the mobility of prostate carcinoma cells : a new therapeutic method for advanced prostate carcinoma2010
- Author(s)
  Tang X, Takekoshi S, Itoh J, Umemura S, Shoji S, Terachi T, Osamura RY
- Journal Title
  
  Int J Oncol
  
  Volume: 37 Pages: 1077-1083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590387
[Journal Article] Protein oxidative damage and heme oxygenase in sunlight exposed human skin : Role of MAPK responses to oxidative stress.2010
- Author(s)
  E.Akasaka, Takekoshi, et al.
- Journal Title
  
  Tokai Journal Experimental Medicine
  
  Volume: 35 Pages: 152-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Selection of buffer pH by the isoelectric point (pI) of the antigen for the efficient heat-induced epitope retrieval : Re-appraisal for nuclear protein patho-biology.2009
- Author(s)
  Kajiya H., Takekoshi S., et al
- Journal Title
  
  Histochem Cell Biol. 132
  
  Pages: 659-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Association of hypoxia-inducible factor-1 expression with histology in epithelial ovarian tumors : a quantitative analysis of HIF-1.2009
- Author(s)
  Miyazawa M., Takekoshi S., et al
- Journal Title
  
  Arch Gynecol Obstet. 279
  
  Pages: 789-796
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Overexpression of E2F-5 correlates with a pathological basal phenotype and a worse clinical outcome.2009
- Author(s)
  Umemura S., Takekoshi S., et al
- Journal Title
  
  British Journal of Cancer 100
  
  Pages: 764-771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Expression of genes related to corticotropin production and glucocorticoid feedback in corticotroph adenoma of dogs with Cushing's disease.2009
- Author(s)
  Teshima T., Takekoshi S., et al
- Journal Title
  
  Domestic Animal Endocrinology 36
  
  Pages: 40249-40249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Expressgenesion of genes related to corticotropin production and glucocorticoid feedback in corticotroph adenomas of dogs with Cushing's disease.2009
- Author(s)
  Teshima T, Hara Y, Takekoshi S, Teramoto A, Osamura RY, Tagawa M
- Journal Title
  
  Domest Anim Endocrinol 36
  
  Pages: 3-12
- Data Source
  KAKENHI-PROJECT-19390105
[Journal Article] The influence of endocrine disrupting chemicals on the proliferation of ERalpha knockdown-human breast cancer cell line MCF-72009
- Author(s)
  Miyakoshi T., Takekoshi S., et al
- Journal Title
  
  Acta Histochemca Cytochemica 42
  
  Pages: 23-28
- NAID
  130007004116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Metastin inhibits migration and invasion of renal cell carcinoma with overexpression of metastinc receptor2009
- Author(s)
  Shoji S, Tang XY, Umemura S, Itoh J, Takekoshi S, Shima M, Usui Y, Nagata Y, Uchida T, Osamura RY, Terachi T
- Journal Title
  
  Eur Urology
  
  Volume: 55 Pages: 441-451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590387
[Journal Article] Pathology, Pathogenesis and Therapy of Growth Hormone (GH)-producing Pituitary Adenomas : Technical Advances in Histochemistry and Their Contribution.2009
- Author(s)
  Osamura Y., Takekoshi S., et al
- Journal Title
  
  Acta Histochemca Cytochemica 42
  
  Pages: 95-104
- NAID
  130000118207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] The Expression of Wnt4 Is Regulated by Estrogen via an Estrogen Receptor Alpha-dependent Pathway in Rat Pituitary Growth Hormone-producine Cells.2009
- Author(s)
  Miyakoshi T., Takekoshi S., et al
- Journal Title
  
  Acta Histochemca Cytochemica 42
  
  Pages: 205-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Coexistence of Corticotroph Adenoma and Thyrotroph Hyperplasia in a Dog.2009
- Author(s)
  Teshima T., Takekoshi S., et al
- Journal Title
  
  Journal of Veterinary Medical Science 1
  
  Pages: 93-98
- NAID
  110007055403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Overexpression of E2F-5 correlates with a pathological basal phenotype and a worse clinical outcome2009
- Author(s)
  Umemura S, Shirane M, Takekoshi S, Kusakabe T, Itoh J, Egashira N, Tokuda Y, Mori K, Osamura RY
- Journal Title
  
  Br J Cancer
  
  Volume: 100 Pages: 764-771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590387
[Journal Article] Selection of buffer pH by the isoelectric point (pI) of the antigen for the efficient heat-induced epitope retrieval : Re-appraisal for nuclear protein patho-biology.2009
- Author(s)
  Hanako Kajiya, Susumu Takekoshi, Mao Takei, Noboru Egashira, Takashi Miyakoshi, Robert Y Osamura
- Journal Title
  
  Histochem Cell Biol. 132
  
  Pages: 659-667
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Pathology, Pathogenesis and Therapy of Growth Hormone (GH)-producing Pituitary Adenomas : Technical Advances in Histochemistry and Their Contribution.2009
- Author(s)
  Yoshiyuki Osamura, Noboru Egashira, Hanako Kajiya, Mao Takei, Maya Tobita, Takashi Miyakoshi, Chie Inomoto, Susumu Takekoshi, Akira Teramoto
- Journal Title
  
  Acta Histochemca Cytochemica 42
  
  Pages: 95-104
- NAID
  130000118207
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Therapeutic strategy targeting the mTOR-HIF-1alpha-VEGF pathway in ovarian clear cell adenocarcinoma.2009
- Author(s)
  Miyazawa M., Takekoshi S., et al
- Journal Title
  
  Pathol Int. 59
  
  Pages: 19-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Trilostane-induced inhibition of cortisol secretion results in reduced negative feedback at the hypothalamic-pituitary axis.2009
- Author(s)
  Teshima T., Takekoshi S., et al
- Journal Title
  
  Domestic Animal Endocrinology 36
  
  Pages: 32-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Overexpression of E2F-5 correlates with a pathological basal phenotype and a worse clinical outcome2009
- Author(s)
  Umemura S, Shirane M, Takekoshi S, Kusakabe T, Itoh J, Egashira N, Tokuda Y, Mori K, and Osamura RY.
- Journal Title
  
  Br J Cancer 100
  
  Pages: 764-771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590348
[Journal Article] Pituitary changes in Propl transgenic mice : Hormone producing tumors and Signet-ring type gonadotropes2008
- Author(s)
  Egashira., Takekoshi S., et al.
- Journal Title
  
  Acta Histochemca Cytochemica 41
  
  Pages: 47-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] X-ray microtomogaphic imaging of three-dimensional structure of softtissues2008
- Author(s)
  Mizutani R., Takekoshi S., et al.
- Journal Title
  
  Tissue Engineering 14
  
  Pages: 359-363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Expression of MSXl in Human Normal Pituitaries and Pituitary Adenomas2008
- Author(s)
  Mizokami Y., Takekoshi S., et al.
- Journal Title
  
  Endocrine Pathology 19
  
  Pages: 54-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Specific Single Chain Variable Fragment (ScFv) antibodies to angiotensin II AT2 Receptor2008
- Author(s)
  Tamura M., Takekoshi S., et al.
- Journal Title
  
  Journal of Molecular Histology 39
  
  Pages: 351-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Expression of hypoxia inducible factor-1a(HIF-1α) and glucose tran sporter-1 (GLUT-1) in ovarian adenocarcinomas2008
- Author(s)
  Yasuda M., Takekoshi S., et. al.
- Journal Title
  
  Oncology Reports 19
  
  Pages: 111-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590381
[Journal Article] Three-dimensional microtomographic imaging of human brain cortex2008
- Author(s)
  Mizutani R., Takekoshi., et al.
- Journal Title
  
  Brain Research 1199
  
  Pages: 53-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Pathology of the human pituitary adenomas2008
- Author(s)
  Osamura Y., Takekoshi S., et al.
- Journal Title
  
  Histochemistry and Cell Biology 130
  
  Pages: 495-507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Metastin inhibits migration and invasion of renal cell carcinoma with overexpression of metastinc receptor2008
- Author(s)
  Shoji S, Tang XY, Umemura S, Itoh J, Takekoshi S, Shima M, Usui Y, Nagata Y, Uchida T, Osamura RY, Terachi T.
- Journal Title
  
  Eur Urol 55
  
  Pages: 441-451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590348
[Journal Article] Expression of MSX1 in human normal pituitaries and pituitary adenomas2008
- Author(s)
  Mizokami Y., Takekoshi S., et. al.
- Journal Title
  
  Endocrine Pathology (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590381
[Journal Article] Hypothesis for the mechanism for heat-induced antigen retrieval occurring on fresh frozen sections without formalin-fixation in immunohistochemistry2008
- Author(s)
  Kakimoto K., Takekoshi S., et al.
- Journal Title
  
  Journal of Molecular Histology 39
  
  Pages: 389-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] X-ray microtomogaphic imaging of three-dimensional structure of soft tissues.2008
- Author(s)
  Ryuta Mizutani, Akihisa Takeuchi, Kentaro Uesugi, Susumu Takekoshi, R.Yoshiyuki Osamura, Yoshio Suzuki
- Journal Title
  
  Tissue Engineering 14
  
  Pages: 359-363
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Association of hypoxia-inducible factor-1 expression with histology in epithelial ovarian tumors : a quantitative analysis of HIF-12008
- Author(s)
  Miyazawa M., Takekoshi S., et al.
- Journal Title
  
  Arch Gynecol Obstet (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Three-dimensional microtomographic imaging of human brain cortex2008
- Author(s)
  Ryuta Mizutani, Akihisa Takeuchi, Kentaro Uesugi, Masami Ohyama, Susumu Takekoshi, R.Yoshiyuki Osamura, Yoshio Suzuki
- Journal Title
  
  Brain Research 1199
  
  Pages: 53-61
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Immunohistochemical detection of somatostatin receptor (SSTR) subty pes 2A and 5 in pituitary adenoma from acromegalic patients2008
- Author(s)
  Takei M., Takekoshi S., et. al.
- Journal Title
  
  Endocrine Pathology (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590381
[Journal Article] ACTH and α-subunit are co-expressed in rare human pituitary corticotroph cell adenomas proposed to originate from ACTH-committed early pituitary progenitor cells2008
- Author(s)
  Suzuki M., Takekoshi S., et. al.
- Journal Title
  
  Endocrine Pathology (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590381
[Journal Article] Three-dimensional microtomographic imaging of human brain cortex2008
- Author(s)
  Mizutani R., Takekoshi S., et. al.
- Journal Title
  
  Brain Research (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590381
[Journal Article] Hypothesis for the mechanism for heat-induced antigen retrieval occurring on fresh frozen sections without formalin-fixation in immunohistochemistry.2008
- Author(s)
  Kochi Kakimoto, Susumu Takekoshi, Katsuhiro Miyajima, R.Yoshiyuki Osamura
- Journal Title
  
  Journal of Molecular Histology 39
  
  Pages: 389-399
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] ACTH and α-subunit are co-expressed in rare human pituitary corticotroph cell adenomas proposed to originate from ACTH-committed early pituitary progenitor cells2008
- Author(s)
  Suzuki M., Takekoshi S., et al.
- Journal Title
  
  Endocrine Pathology 19
  
  Pages: 17-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] Metastin Inhibits Migration and Invasion of Renal Cell Carcinoma with Overexpression of Metastin Receptor2008
- Author(s)
  Shoji., Takekoshi S., et al.
- Journal Title
  
  European Urology. 55
  
  Pages: 441-451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590385
[Journal Article] An insight of subcellular localization of pituitary hormone mRNA : observation under electron microscopy and confocal laser scanning microscopy2007
- Author(s)
  A, Itoh J, Utsunomiya, H, Takekoshi, S, Osamura, RY
- Journal Title
  
  New Messenger RNA Research Communications, Nova Science Publishers, Inc. Matsuno
  
  Pages: 69-86
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591608
[Journal Article] Granulogenesis in Non-neuroendocrine COS-7 Cell Induced by EGFP-tagged Chromogranin A Gene Transfection : Identical and Distinct Distribution of CgA and EGFP2007
- Author(s)
  Inomoto C, Umemura S, Egashira N, Minematsu T, Takekoshi S, Itoh Y, Itoh J, Taupenot L, O'Connor D T, Osamura RY.
- Journal Title
  
  J Histochem Cytochem 55
  
  Pages: 487-493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590348
[Journal Article] An Up-to-Date Anti-Cancer Treatment Strategy Focusing on HIF-lα Suppression:lts Application for Refractory Ovarian Cancer2007
- Author(s)
  Fujita M., Takekoshi S., et. al.
- Journal Title
  
  Acta Histochemca Cytochemica 40
  
  Pages: 139-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590381
[Journal Article] Various Molecular Species of Diacylglycerol Hydroperoxide Activate Human Neutrophils via PKC Activation, but 1-Palmitoyl-2-Linoleoyl Diacylglycerol Hydroperoxide Is the Most Potent Activator2007
- Author(s)
  Kambayashi Y, Takekoshi S., et al.
- Journal Title
  
  J Clin. Biochem. ＆ Nutr (In press)
- Data Source
  KAKENHI-PROJECT-18590381
[Journal Article] Quantification of neutral cysteine protease bleomycin hydrolase and its localization in rat tissues2006
- Author(s)
  Kamata Y., Takekoshi S., et al.
- Journal Title
  
  J Biochemistry (In press)
- NAID
  10020101986
- Data Source
  KAKENHI-PROJECT-18590381
[Journal Article] Mechanism of intracellular transport and secretion of pituitary hormone, with an insight of the subcellular localization of pituitary hormone and its mRNA2006
- Author(s)
  Matsuno A., Takekoshi S., et al.
- Journal Title
  
  Current Trends in Endocrinology (In press)
- Data Source
  KAKENHI-PROJECT-18590381
[Journal Article] Sevoflurane stimulates MAP kinase signal transduction through the activation of PKC α and β II in fetal rat cerebral cortex cultured neuron2006
- Author(s)
  Hasegawa J., Takekoshi S., et al.
- Journal Title
  
  Acta Histochemca Cytochemica 39
  
  Pages: 163-712
- NAID
  110006203405
- Data Source
  KAKENHI-PROJECT-18590381
[Journal Article] PTTG is a secretory protein in human pituitary adenomas and in mouse pituitary tumor cell lines :2006
- Author(s)
  Minematsu T., Takekoshi S., et al.
- Journal Title
  
  Endocrine Pathology (In press)
- Data Source
  KAKENHI-PROJECT-18590381
[Journal Article] Rab proteins and the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) system in the secretion of pituitary hormones2006
- Author(s)
  Matsuno A., Takekoshi S., et al.
- Journal Title
  
  Current Trends in Endocrinology (In press)
- Data Source
  KAKENHI-PROJECT-18590381
[Journal Article] Estrogen receptor-negative and human epidermal growth factor receptor 2-negative breast cancer tissue have the highest Ki-67 labeling index and EGFR expression2005
- Author(s)
  Umemura S., Takekoshi S., et al.
- Journal Title
  
  Oncology Reports 14
  
  Pages: 337-343
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Three-dimensional Imaging of the Intracellular Localization of Growth Hormone and Prolactin and Their mRNA Using Nanocrystal (Quantum Dot) and Confocal Laser Scanning Microscopy Techniques.2005
- Author(s)
  Matsuno A., Takekoshi S., et al.
- Journal Title
  
  J Histochemistry Cytochemistry 53
  
  Pages: 833-838
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Dietary soybean enhances Pit-1 dependent pituitary hormone production in iodine deficient rats.2005
- Author(s)
  Kajiya H., Takekoshi S., et al.
- Journal Title
  
  Journal of Molecular Histology 36
  
  Pages: 263-272
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Histochemical technologies for genomics and proteomics : Laser capture microdissection (LCM) and tissue microarray (TMA)2005
- Author(s)
  Osamura Y., Takekoshi S., et al.
- Journal Title
  
  Acta Histochemica Cytochemica 38
  
  Pages: 185-188
- NAID
  110003161317
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Two or three dimensional imagings of simultaneous visualization of rat pituitary hormone and its mRNA2005
- Author(s)
  Matsuno A., Takekoshi S., et al.
- Journal Title
  
  Acta Histochemica Cytochemica 38
  
  Pages: 253-256
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Pit-1 Gene Inhibition Using Small Interfering RNAs in Rat Pituitary GH Secreting Cell Line.2005
- Author(s)
  Miyai S., Takekoshi S., et al.
- Journal Title
  
  Acta Histochemica Cytochemica 38
  
  Pages: 107-114
- NAID
  110003161236
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Kinobeon A, Purified from cultured safflower cells, is a novel and potent singlet oxygen quencher.2005
- Author(s)
  Kambayashi Y., Takekoshi S., et al.
- Journal Title
  
  Acta Biochimica Polonica 52
  
  Pages: 903-908
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Molecular and histological studies of pituitary tumorigenesis using experimental animal models.2005
- Author(s)
  Minematsu T., Takekoshi S., et al.
- Journal Title
  
  Acta Histochemica Cytochemica 38
  
  Pages: 87-92
- NAID
  110003161233
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Induction of GH, PRL, and TSHbeta mRNA by transfection of Pit-1 in a human pituitary adenoma-derived cell line.2005
- Author(s)
  Miyai S., Takekoshi S., et al.
- Journal Title
  
  Cell Tissue Research 322
  
  Pages: 269-277
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Estrogen receptor-negative and human epidermal growth factor receptor 2-negative breast cancer tissue have highest Ki-67 labeling index and EGFR expression : Gene amplification does not contribute to EGFR expression.2005
- Author(s)
  Umemura S, Takekoshi, Suzuki Y, Saitoh Y, Tokuda Y, Osamura RY.
- Journal Title
  
  Oncology reports 13
  
  Pages: 337-343
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590317
[Journal Article] Estrogen receptor-negative and human epidermal growth factor receptor 2-negative breast cancer tissue have the highest Ki-67 labeling index and EGFR expression : Gene amplification does not contribute to EGFR expression.2005
- Author(s)
  Umemura S, Takekoshi S, Suzuki Y, Saitoh Y, Tokuda Y, Osamura RY
- Journal Title
  
  Oncology Reports 14
  
  Pages: 337-343
- Data Source
  KAKENHI-PROJECT-15590317
[Journal Article]2005
- Author(s)
  Matsuno A., Takekoshi S., et al.
- Journal Title
  
  J Histochemistry Cytochemistry 53
  
  Pages: 1177-1180
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Recent progress in studies of pituitary tumor pathogenesis.2005
- Author(s)
  Minematsu T., Takekoshi S., et al.
- Journal Title
  
  Endocrine 28
  
  Pages: 37-41
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Quercetin Enhances Melanogenesis by Increasing Activity and Synthesis of Tyrosinase in Human Melanoma Cells2004
- Author(s)
  Nagata H., Takekoshi S., et al.
- Journal Title
  
  Pigment Cell Research 17
  
  Pages: 66-73
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Production of pituitary hormone by human pituitary adenoma is under autocrine and paracrine regulationof hypothalamic hormones secreted from adenoma cells2004
- Author(s)
  Matsuno A., Takekoshi S., et al.
- Journal Title
  
  Acta Histochemca Cytochemica 36
  
  Pages: 405-420
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Quercetin induced melanogenesis in a reconstituted three-dimensional human epidermal model2004
- Author(s)
  Takeyama R., Takekoshi S., et al.
- Journal Title
  
  Journal of Molecular Histology 35
  
  Pages: 157-165
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Modification of p53 immunoexpression associated with chemotherapy regimens in advanced and refractory ovarian cancers2004
- Author(s)
  Hirasawa Y., Takekoshi S., et al.
- Journal Title
  
  Acta Histochemca Cytochemica 37
  
  Pages: 15-20
- NAID
  110003144312
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Cocaine- and amphetamine-regulated transcript peptide in the rat anterior pituitary gland is localized in gonadotrophs and suppresses prolactin secretion2004
- Author(s)
  Kuriyama G., Takekoshi S., et al.
- Journal Title
  
  Endocrinology 2004
  
  Pages: 2542-2550
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Heterogeneous gene alterations in primary breast cancer contribute to discordance between primary and asynchronous metastatic/recurrent sites : HER2 gene amplification and p53 mutation.2003
- Author(s)
  Sekido Y, Umemura S, Takekoshi S, Suzuki Y, Tokuda Y, Tajima T, Osamura RY.
- Journal Title
  
  Int J Oncol 22
  
  Pages: 1225-1232
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590317
[Journal Article] Implication of genetic alterations caused by progesterone administration in endometrial hyperplasia and adenocarcinoma
- Author(s)
  Yasuda M., Takekoshi S., et al.
- Journal Title
  
  International Journal of Gynecological Cancer (In press)
- Data Source
  KAKENHI-PROJECT-16590326
[Journal Article] Expression of FOXL2 in Human Normal Pituitaries and Pituitary Adenomas.
- Author(s)
  Noboru Egashira, Susumu Takekoshi, Mao Takei, Akira Teramoto, Robert Yoshiyuki Osamura
- Journal Title
  
  Modern Pathology (in press)
- Data Source
  KAKENHI-PROJECT-20590385
[Presentation] 脳虚血再灌流における酸化型DAG及びPKCの関与2018
- Author(s)
  大信田慎一，合田圭佑，安井雄三，北谷佳那恵，山本順寛，竹腰進
- Organizer
  第71回日本酸化ストレス学会
- Data Source
  KAKENHI-PROJECT-16K08721
[Presentation] Naイオンを用いたDAGOOH異性体の分析法2018
- Author(s)
  加藤俊治、仲川清隆、竹腰進
- Organizer
  日本過酸化脂質・抗酸化物質学会　第26回年会
- Data Source
  KAKENHI-PROJECT-16K08721
[Presentation] 脂溶性情報伝達物質の過酸化による病態発生の分子機構2018
- Author(s)
  竹腰　進
- Organizer
  日本食品科学工学会第65回大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08721
[Presentation] 質量分析による生体脂質過酸化機構の解明2018
- Author(s)
  加藤俊治、北谷佳那恵、宮澤陽夫、仲川清隆、竹腰進
- Organizer
  第71回日本酸化ストレス学会
- Data Source
  KAKENHI-PROJECT-16K08721
[Presentation] セレン及びグルタチオン欠乏モデルラットの作製に関する検討2018
- Author(s)
  合田圭佑，安井雄三，大信田慎一，北谷佳那恵，竹腰進
- Organizer
  第71回日本酸化ストレス学会
- Data Source
  KAKENHI-PROJECT-16K08721
[Presentation] 下垂体前葉細胞の機能分化と腺腫発生2017
- Author(s)
  竹腰進、井野元智恵、嘉納麻耶、寺本明、長村義之
- Organizer
  第90回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08721
[Presentation] 皮弁の虚血再灌流傷害における酸化型DAGの関与とEbselenの効果2017
- Author(s)
  北谷佳那恵、黒木尭比古、赤松正、竹腰進
- Organizer
  日本酸化ストレス学会
- Data Source
  KAKENHI-PROJECT-16K08721
[Presentation] Nanotomography of brain networks2017
- Author(s)
  Rino Saiga, Ryuta Mizutani, Susumu Takekoshi, Motoki Osawa, Makoto Arai, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada, Yoshio Suzuki, Vincent De Andrade, Francesco De Carlo
- Organizer
  American Physical Society, March Meeting 2017
- Place of Presentation
  Ernest Morial Convention Center, New Orleans, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282250
[Presentation] 肺扁平上皮癌におけるPar3のクラスタリング局在2017
- Author(s)
  竹腰進、仁藤まどか、北谷佳那恵、岩﨑正之
- Organizer
  第58回日本組織細胞化学会総会
- Data Source
  KAKENHI-PROJECT-16K08721
[Presentation] Ebselen ameliorates liver fibrosis-induced by carbon tetrachloride in mice2017
- Author(s)
  Kanae Kitatani, Susumu Takekoshi
- Organizer
  he 8th Joint Meeting of Society for Free Radical Research Australasia and Japan with International Symposium on Coenzyme Q10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08721
[Presentation] Reconstruction of brain network with micro/nano tomography2017
- Author(s)
  Rino Saiga, Ryuta Mizutani, Susumu Takekoshi, Motoki Osawa, Makoto Arai, Akihisa Takeuchi, Kentaro Uesugi, Yoshio Suzuki, Vincent De Andrade, Francesco De Carlo
- Organizer
  Microscopy Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282250
[Presentation] A METHOD FOR ESTIMATING SAMPLE IMAGE RESOLUTION2016
- Author(s)
  Ryuta Mizutani, Rino Saiga, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Makoto Arai, Kenichi Oshima, Masanari Itokawa, Akihisa Takeuchi, Kentaro Uesugi, Yasuko Terada, and Yoshio Suzuki
- Organizer
  13th International Conference on X-Ray Microscopy
- Place of Presentation
  Oxford Univ, United Kingdom
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282250
[Presentation] 虚血再灌流障害皮弁モデルにおける組織傷害と酸化型DAGの関する検討2016
- Author(s)
  黒木尭比古、北谷佳那恵、赤松正、竹腰進
- Organizer
  第25回日本形成外科学会基礎学術集会
- Place of Presentation
  ナレッジキャピタルコングレ・コンベンションセンター（大阪府大阪市）
- Year and Date
  2016-09-15
- Data Source
  KAKENHI-PROJECT-16K08721
[Presentation] 皮弁組織傷害における酸化型DAGの役割2016
- Author(s)
  黒木尭比古、北谷佳那恵、竹腰進、赤松正
- Organizer
  第69回日本酸化ストレス学会学術集会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-16K08721
[Presentation] ブレオマイシン誘導性肺線維症における酸化型DAGの役割2016
- Author(s)
  壺井貴朗、矢ヶ﨑秀彦、岩﨑正之、竹腰進
- Organizer
  第69回日本酸化ストレス学会学術集会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-16K08721
[Presentation] PKC-MAPKシグナル経路を介した肝星細胞の活性化と肝線維化増悪のメカニズムの解析2016
- Author(s)
  北谷佳那恵、竹腰進
- Organizer
  第69回日本酸化ストレス学会学術集会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-16K08721
[Presentation] Three-Dimensional Neuronal Structure of Human Cerebral Cortex Determined by Synchrotron-Radiation Microtomography2015
- Author(s)
  Rino Saiga, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Akio Tsuboi, Motoki Osawa, Makoto Arai, Kenichi Oshima, Masanari Itokawa, Kentaro Uesugi, Akihisa Takeuchi, Yasuko Terada, Yoshio Suzuki and Ryuta Mizutani
- Organizer
  Microscopy & Microanalysis 2015 Meeting
- Place of Presentation
  Oregon Convention Center (Portland, USA)
- Year and Date
  2015-08-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25610126
[Presentation] ヒト大脳皮質の神経回路の三次元解析2015
- Author(s)
  藤巻知央，菊池亜弥，蓮見真子，竹腰進，井野元智恵，中村直哉，坪井秋男，大澤資樹，新井誠，大島健一，糸川昌成，上杉健太朗，竹内晃久，寺田靖子，鈴木芳生，雑賀里乃，水谷隆太
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸国際会議場（神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25610126
[Presentation] Three-Dimensional Neuronal Structure of Human Cerebral Cortex Determined by Synchrotron-Radiation Microtomography2015
- Author(s)
  Rino Saiga, Susumu Takekoshi, Chie Inomoto, Naoya Nakamura, Akio Tsuboi, Motoki Osawa, Makoto Arai, Kenichi Oshima, Masanari Itokawa, Kentaro Uesugi, Akihisa Takeuchi, Yasuko Terada, Yoshio Suzuki and Ryuta Mizutani
- Organizer
  Microscopy & Microanalysis 2015 Meeting
- Place of Presentation
  Oregon Convention Center (Portland, USA)
- Year and Date
  2015-08-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282250
[Presentation] ヒト大脳皮質の神経回路の三次元解析2015
- Author(s)
  藤巻知央，菊池亜弥，蓮見真子，竹腰進，井野元智恵，中村直哉，坪井秋男，大澤資樹，新井誠，大島健一，糸川昌成，上杉健太朗，竹内晃久，寺田靖子，鈴木芳生，雑賀里乃，水谷隆太
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸国際会議場（神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25282250
[Presentation] Ｘ線マイクロトモグラフィ法によるヒト大脳皮質の三次元構造解析2013
- Author(s)
  水谷隆太、雑賀里乃、竹腰進、井野元智恵、中村直哉、大澤資樹、新井誠、大島健一、糸川昌成、竹内晃久、上杉健太朗、鈴木芳生
- Organizer
  SPring-8 シンポジウム2013
- Place of Presentation
  京都大学宇治おうばくプラザ
- Data Source
  KAKENHI-PROJECT-25610126
[Presentation] Ｘ線マイクロトモグラフィ法によるヒト大脳皮質の三次元構造解析2013
- Author(s)
  水谷隆太、雑賀里乃、竹腰進、井野元智恵、中村直哉、大澤資樹、新井誠、大島健一、糸川昌成、竹内晃久、上杉健太朗、鈴木芳生
- Organizer
  SPring-8 シンポジウム2013
- Place of Presentation
  京都大学宇治おうばくプラザ
- Data Source
  KAKENHI-PROJECT-25282250
[Presentation] Ｘ線マイクロトモグラフィ法によるヒト脳組織の三次元構造解析2013
- Author(s)
  雑賀里乃、水谷隆太、竹腰進、井野元智恵、中村直哉、大澤資樹、新井誠、大島健一、糸川昌成、竹内晃久、上杉健太朗、鈴木芳生
- Organizer
  第74回応用物理学会秋季学術講演会
- Place of Presentation
  同志社大学京田辺校
- Data Source
  KAKENHI-PROJECT-25610126
[Presentation] Ｘ線マイクロトモグラフィ法によるヒト脳組織の三次元構造解析2013
- Author(s)
  雑賀里乃、水谷隆太、竹腰進、井野元智恵、中村直哉、大澤資樹、新井誠、大島健一、糸川昌成、竹内晃久、上杉健太朗、鈴木芳生
- Organizer
  第74回応用物理学会秋季学術講演会
- Place of Presentation
  同志社大学京田辺校
- Data Source
  KAKENHI-PROJECT-25282250
[Presentation] ジアシルグリセロールの酸化物は四塩化炭素による肝傷害を促進させる2012
- Author(s)
  鳥海　健太郎，高木　達也,堀越　洋輔, 長村　義之, 山本　順寛, 中村　直哉，竹腰　進
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590464
[Presentation] ビタミンEによる過酸化ジアシルグリセロール産生低下は四塩化炭素誘起肝傷害を抑制する2012
- Author(s)
  鳥海　健太郎，高木　達也,堀越　洋輔, 長村　義之, 山本　順寛, 中村　直哉，竹腰　進
- Organizer
  第65日本酸化ストレス学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-24590464
[Presentation] PKCδスプライシングバリアントによる酸化ストレス誘導性細胞傷害の抑制機構の解明2012
- Author(s)
  高木　達也，堀越　洋輔，鳥海　健太郎，中村　直哉，竹腰　進
- Organizer
  第65日本酸化ストレス学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-24590464
[Presentation] 酸化ストレス傷害に対するPKCδスプライシングバリアントの抑制作用2012
- Author(s)
  高木　達也，鳥海　健太郎，竹腰　進
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590464
[Presentation] Oxidative stress mediated NF-kB activation regulates epidermal cell proliferation and differentiation in psoriasis2011
- Author(s)
  Tomoko Kojima, Emiko Akasaka, Masayuki Kato, Tomotaka Mabuchi, Norihiro Ikoma, Takashi Matsuyama, Akira Ozawa, Yosuke Horikoshi, Kentarou Toriumi, Hideyo Henzan, Susumu Takekoshi, Naoya Nakamura
- Organizer
  36^<th> The Japanase Society for Investigative Dermatology
- Place of Presentation
  京都国際会議場(京都市)
- Data Source
  KAKENHI-PROJECT-21591446
[Presentation] Oxidative stress mediated NF-kB activation regulates epidermal cell proliferation and differentiation in psoriasis2011
- Author(s)
  小島知子, 赤坂江美子, 生駒憲広, 竹腰進, 小澤明
- Organizer
  日本研究皮膚科学会第36回年次学術大会・総会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-21591446
[Presentation] Relationship between antioxidative enzymes and oxidative stress using immunohistochemical analysis in chronic UV-exposed human skin2010
- Author(s)
  Emiko Akasaka, Susumu Takekoshi, Shoutarou Tsutiya, Kentarou Toriumi, Tomotaka Mabuchi, Norihiro Ikoma, Shiho Tamiya, Takashi Matsuyama, Muneo Miyasaka, Yoshiyuki Osamura and Akira Ozawa
- Organizer
  19th Congress of the EADV
- Place of Presentation
  Swedish Exhibition Centre(ヨーテボリ)
- Data Source
  KAKENHI-PROJECT-21591446
[Presentation] 酸化ストレスによる細胞形態変化め分子機構解析2010
- Author(s)
  竹腰進, 他
- Organizer
  第42回日本臨床分子形態学会総会
- Place of Presentation
  三島
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-20590385
[Presentation] SSTR2aをターゲットとする前立腺癌の分子標的治療に関する基礎的研究2010
- Author(s)
  唐小燕、竹腰進、梅村しのぶ
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京(京王プラザホテル)
- Year and Date
  2010-04-29
- Data Source
  KAKENHI-PROJECT-22590320
[Presentation] SSTR2aをターゲットとする前立腺癌の分子標的治療に関する基礎的研究2010
- Author(s)
  唐小燕,梅村しのぶ.竹腰進
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-22590320
[Presentation] 免疫組織化学の高感度検出法～技術と応用～2009
- Author(s)
  竹腰進
- Organizer
  第50回日本組織細胞化学会総会ランチョンセミナー
- Place of Presentation
  滋賀県大津市
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-20590385
[Presentation] The relationship between antioxidative enzymes and oxidative stress using immunohistochemical analysis in chronic UV exposed human skin clinically2009
- Author(s)
  Emiko Akasaka, Susumu Takekoshi, Shoutarou Tsutiya, Kentarou Toriumi, Mabuchi Tomotaka, Norihiro Ikoma, Shiho Tamiya, Takashi Matusyama, Muneo Miyasaka, Yoshiyuki Osamura, Akira Ozawa
- Organizer
  34^<th> The Japanase Society for Investigative Dermatology
- Place of Presentation
  JALリゾートシーホークホテル福岡(福岡市)
- Data Source
  KAKENHI-PROJECT-21591446
[Presentation] 皮膚組織における紫外線・酸化ストレス障害に応答するシグナル伝達と抗酸化システムの検討2009
- Author(s)
  赤坂江美子、竹腰進、鳥海健太郎、土屋翔太郎、宮坂宗男、長村義之、小澤明
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2009-05-03
- Data Source
  KAKENHI-PROJECT-21591446
[Presentation] Advantages of Laser Microdissection in Histochemistry, Molecular Biology and Pathology2008
- Author(s)
  Takekoshi S., et al.
- Organizer
  13^<th> International Congress of Histochemistry and Cytochemistry. Workshop lecture
- Place of Presentation
  Poland
- Year and Date
  2008-08-24
- Data Source
  KAKENHI-PROJECT-20590385
[Presentation] レーザーマイクロダイセクション法の分子病理学への応用2008
- Author(s)
  竹腰進, 他
- Organizer
  第97回日本病理学会総会ランチョンセミナー
- Place of Presentation
  金沢
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-20590385
[Presentation] レーザーマイクロダイセクションと病理診断2007
- Author(s)
  竹腰進
- Organizer
  第32回組織細胞化学講習会
- Place of Presentation
  京都
- Year and Date
  2007-08-08
- Data Source
  KAKENHI-PROJECT-18590381
[Presentation] Recent progress in Iaser capture microdissection for molecular histology2007
- Author(s)
  Takekoshi S
- Organizer
  第48回日本組織細胞化学会総会
- Place of Presentation
  甲府
- Year and Date
  2007-09-29
- Data Source
  KAKENHI-PROJECT-18590381
[Presentation] Exploitation of laser capture microdissection for the analysis of gene mutation and mRNA expression2006
- Author(s)
  Susumu Takekoshi, et. al.
- Organizer
  The Japanese Society of Histochemistry and Cytochemistryワークショップ
- Place of Presentation
  アメリカ
- Year and Date
  2006-08-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590381
[Presentation] Laser Capture Microdissectionを用いた遺伝子解析法の細胞標本への応用2006
- Author(s)
  竹腰進, 他
- Organizer
  第47回臨床細胞学会シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2006-06-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590381
[Presentation] Building human brain network in electron density map determined by X-ray microtomography
- Author(s)
  Rino Saiga, Susumu Takekoshi, Naoya Nakamura, Akihisa Takeuchi, Kentaro Uesugi, Yoshio Suzuki, and Ryuta Mizutani
- Organizer
  23rd Congress and General Assembly of the International Union of Crystallography
- Place of Presentation
  Palais des congres de Montreal, Canada
- Year and Date
  2014-08-05 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-25282250
[Presentation] Building human brain network in electron density map determined by X-ray microtomography
- Author(s)
  Rino Saiga, Susumu Takekoshi, Naoya Nakamura, Akihisa Takeuchi, Kentaro Uesugi, Yoshio Suzuki, and Ryuta Mizutani
- Organizer
  23rd Congress and General Assembly of the International Union of Crystallography
- Place of Presentation
  Palais des congres de Montreal (Montreal, Canada)
- Year and Date
  2014-08-05 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-25610126

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TAKEKOSHI Susumu 竹腰 進

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脂溶性情報伝達分子の脂質過酸化反応を起点とする肝線維化の分子機構の解析Principal InvestigatorOngoing

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Analysis of molecular mechanism of oxidative stress regulation by RNA splicingPrincipal Investigator

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Molecular mechanisms of particular defense system against oxidative stress induced by the control of signalingPrincipal Investigator

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TAKEKOSHI Susumu 竹腰進