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NAGINO MASATO  梛野 正人

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… Alternative Names

NAGINO Masato  梛野 正人

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Researcher Number 20237564
Other IDs
Affiliation (Current) 2022: 愛知県がんセンター(研究所), 副総長, 副総長
Affiliation (based on the past Project Information) *help 2020 – 2021: 愛知県がんセンター(研究所), 副総長, 副総長
2010 – 2021: Nagoya University, 医学系研究科, 教授
2011 – 2016: 名古屋大学, 医学(系)研究科(研究院), 教授
2012: 名古屋大学, 医学(系)・研究科(研究院), 教授
2007 – 2012: Nagoya University, Graduate School of Medicine, Assistant Professor … More
2010: 名古屋, 医学系研究科, 教授
2008 – 2010: Nagoya University, 大学院・医学研究科, 教授
2007 – 2008: Nagoya University Graduate School of Medicine, Division of Surgical Oncology, Professor
2007: 名古屋大学, 大学院・医学系・研究科, 教授
2006: 名古屋大学, 大学院・医学研究科, 教授
2004 – 2006: 名古屋大学, 大学院医学系研究科, 助教授
2003 – 2006: 名古屋大学, 大学院・医学系研究科, 助教授
2003: Nagoya University, Graduate School of Medicine, Associate Professor, 大学院・医学家研究科, 助教授
2002: Nagoya University, University Hospital, Assistant Professor, 医学部附属病院, 講師
2001 – 2002: University Hospital, Nagoya University, Assistant Professor, 医学部・附属病院, 講師
1995 – 2000: Nagoya University・1st Dep.of Surgery, Assistant Professor, 医学部, 講師
1998: 名古屋大学部, 医学部, 格子
1992 – 1994: 名古屋大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Digestive surgery / Digestive surgery / Basic Section 55020:Digestive surgery-related
Except Principal Investigator
Digestive surgery / Digestive surgery / Basic Section 55020:Digestive surgery-related / General surgery / Laboratory medicine / General surgery
Keywords
Principal Investigator
肝再生 / 胆管癌 / Ipsilateral approach / Apoptosis / Liver regeneration / 門脈枝塞栓術 / 血管内皮 / TNF-α / NFκB / Interleukin-6 … More / NF-κB / 胆管癌幹細胞 / 分子標的治療 / 肝門部胆管癌 / 膵癌 / セリンスレオニンキナーゼ / 肝虚血・再灌流 / 一酸化窒素 / 肝障害 / 肝虚血・再潅流 / 経皮経肝門脈枝塞栓術 / 三区域門脈枝塞栓術 / 門脈・肝動脈塞栓術 / 門脈血流速度 / 超音波Doppler検査 / 肝門部胆肝癌 / 胆嚢癌 / 肝切除術 / 術後肝不全 / Percutaneous transhepatic protal vein embolization / Trisegment portal vein embolization / Portal plus arterial embolization / Portal blood flow velocity / Doppler ultrasound / 虚血再灌流障害 / ブレコンディショニング / 肝不全 / 高脂血症 / 白血球 / クッパー細胞 / 接着分子 / プレコンディショニング / 虚血再灌流傷害 / 肝細胞傷害 / 肝微小循環 / SWOP / Ischemia reperfusion injury / Preconditioning / Liver failure / Hypercholesterolemia / Leukocyte / Kupffer cell / Adhesion molecule / 門脈血流 / インターロイキン-6 / ストレッチストレス / 門脈内皮ストレッチ / 門脈内径 / Portal vein embolization / Portal blood flow / Endothelial cell / Stretch stress / NF κ B / 持続伸展刺激 / インテグリン / 機械受容変換 / 伸展刺激 / IL-6 / IKKα / liver regeneration / portal vein embolization / endothelial cell / continuous stretch / interleukin-6 / integrin / mechanotransduction / 融合遺伝子 / 核酸医薬 / ノンコーディングRNA … More
Except Principal Investigator
Nek2 / 肝不全 / apoptosis / PPARγ / GW9662 / 閉塞性黄疸 / 胆管癌 / bacterial translocation / nitric oxide / TFF / マイクロRNA / プロテオミクス / 網羅的発現解析 / 分子標的治療 / 肝再生 / FAK / TLR7 / 食道癌 / 大腸癌 / 膵癌 / TPX2 / Danger signal / 肝虚血再灌流障害 / 術後肝不全 / 胆管炎 / 胆道ドレナージ / 虚血再潅流障害 / 肝 / L-NAME / エンドトキシン / 多臓器不全 / endotoxin / 細菌感染 / サイトカイン / bacterial infection / SIRS / 遺伝子治療 / 接着分子 / ICAM-1 / 乳癌 / mitosis / IL-10 / IL-12 / Toll-like receptor / パイエル板 / SHPS-1 / cysteine / propagylglycine / NaHS / siRNA / IL-6 / STAT3 / bile duct ligation / TFF1 / 術後肝障害 / 臨床検査システム / マススペクトロメトリー / バイオインフォマティクス解析 / cancer stem cell / circulating tumor cell / Circulating Tumor Cell / stem cell / p63 / Tyramide signal amplification system / 化学発癌 / 疫学 / 胆嚢癌 / 重金属 / 活性酸素 / 癌疫学 / エストロゲン / セロトニン / 門脈結紮 / hedgehog Cyclopamine / hedgehogシグナル / シクロパミン / hedgehog / cyclopamine / NeK2 / トランスレーショナルリサーチ / カルシトニン / CGRP / PPAR_Y / 15D-PGJ_2 / 15d-PGJ2 / TLK1 / 分子診断 / グルタチオン / Gamma-glutamyltransferase / 微小転移 / 微小転移関連遺伝子 / 微小転移開連遺伝子 / microscopic abscess / 免疫誘導阻止関連遺伝子 / Hedgehog / 相互マシンラーニング法 / Senescence / HJURP / 化学療法関連肝障害 / Blue liver症候群 / 治療抵抗性遺伝子 / IGFBP-3 / Chromothripsis / Denger Signal / 分枝鎖アミノ酸 / 肝虚血再潅流障害 / 分子進化 / 肝門部胆管癌 / 肝切除術 / 門脈枝塞栓術 / 経皮経肝胆管ドレナージ / 肝尾状葉 / 肝再生能 / xanthine oxidase / 肝虚血 / histo chemistry / xanthine oxiclase / histochemistry / free radicals / Hilar cholangiocarcinoma / Obstructive Jaundice / Hepatectomy / Liver failure / Portal vein embolization / Biliary drainage / Cholangitis / Caudate lobe / 胆汁鬱滞 / ミトコンドリア / 酸化的リン酸化 / 区域性胆汁鬱滞 / 外科学 / 分子生物学 / 胆汁うっ滞 / 区域性胆汁うっ滞 / cholestasis / mitochondria / oxidative phosphorylation / segmental cholestasis / cholangitis / bile ductcarcinoma / surgery / molecular-biology / 小腸血流 / 手術 / 小腸粘膜障害 / Bacterial translocation / 食道切除術 / 小腸虚血再灌流障害 / 小腸虚血再灌流 / 小腸組織血流 / xanthine oxidase活性 / ischemic / reperfusion injury / intestinal blood flow / operation / 肝細胞障害 / ショック蛋白 / 腫瘍壊死因子 / インターロイキン-12 / インターロイキン-10 / 生体防御機構 / 腫瘍懐死因子-α / 熱ショックタンパク質 / DibutyrylサイクリックAMP / インターロイキン10 / マクロファージ / Salmonella / monoclonal antibody / TNFα / liver cell injury / cytokines / heat shok protein / TNF-alpha tumor necrosis factor / interleukin-12 / interleukin-10 / 敗血症 / 網内系機能 / 酸化窒素 / NO合成酵素 / 出血性ショック再蘇生モデル / 大量肝切除モデル / Nitric Oxide / 肝網内系機能 / 手術侵襲 / 肝微小循環 / 出血性ショック / Kupper細胞 / インターロイキン / sepsis / hepatic failure / reticuloendothelial function / multiple organ failure / NO synthetase / 発現ベクター / 腹膜播腫癌 / 遺伝子発現制御 / 腹膜播種癌 / レトロウイルスベクター / ドキシサイクリン / on / off制御 / GFP / gene therapy / retroviral vector / peritoneal dessemination / transcriptional regulation / 胆汁酸 / 大腸発癌 / 促進剤 / アルキル化剤 / リトコール酸 / DNAポリメラーゼβ / 塩基除去修復系 / 阻害剤 / DNAポリメラーゼ / DNA修復阻害 / Lithocholic acid / DNA polymerase / Tumor promoter / Colon carcinogenesis / bile acids / alkylating agents / Inhibition / Base-excision repair / 腸管うっ滞 / 腸内細菌 / 常在菌 / 炎症 / 血管内皮 / intestinal stasis / enteric microflora / indigenous gastrointestinal microflora / inflammation / adhesion molecules / endothelium / p73遺伝子 / アポトーシス / 筋上皮 / p53遺伝子 / 筋上皮細胞 / p73 gene / mammary carcinoma / myoepithelium / p53 gene / 胆管 / 萎縮 / 肥大 / エタノール / 胆管能動的閉鎖法 / 残肝体積増大法 / 胆管内無水エタノール注入 / liver / bile duct / atrophy / hypertrophy / ethanol / Kupffer細胞 / 感染免疫 / kupffer細胞 / 胆汁内瘻 / obstructive cholestasis / Kupffer cell / biliary dramage / Peyer's patch / Breast Cancer / ステロイド / 基礎肝汁流量 / 硫化水素 / cystathionine γ-lyase / 重炭酸イオン / 高ビリルビン血症 / 胆汁 / hemoxygenase / cystathionineγ-lyase / 一酸化炭素 / 胆汁中重炭酸イオン / デキサメサゾン / ラット分離還流肝 / glibenclamide / steroid / basal bile output / hydrogen sulfide / cytathionine γ-lyase / biabonate / molecular targeted therapy / 内皮細胞持続伸展 / インテグリン / シグナル伝達経路 / 非侵襲下門脈結紮モデル / 経皮経肝門脈塞栓術 / NF-kB / 類洞内皮細胞 / 持続伸展刺激 / インターロイキン6 / liver regeneration / continuous stretch in ECs / integrin / signaling cascade / surgical non-stress portal vein ligation model / 胆管結紮 / PPAR-γ / 15d-PGJ_2 / RAGE / 術後感染症 / 融合遺伝子 / 癌幹細胞 / ノンコーディングRNA / システイン / 肝障害 / 肝星細胞 / エンドセリン / 敗血症性ショックモデル / 必須アミノ酸 / Pre-metastatic niche / 血管新生関連分子 / ビサボロール / 誘導体 / 深紫外線LED / 細胞障害作用 / 癌治療 / 前癌病変 / 癌 / 脂肪幹細胞 / 周術期対策 / 血中循環腫瘍細胞 / 生着関連遺伝子 / 非対称分裂 / 自己組織化 / invisible膵癌 / エクソソーム / バイオマーカー / Barrett上皮 / Barrett食道 / barrett食道 / 食道 / 肝細胞癌 / 原発性肝癌 / TLR4 / 予防治療法 / 腹腔鏡下肝切除 / Navigation Surgery / ナビゲーション手術 / リアルタイムナビゲーションシステム Less
  • Research Projects

    (60 results)
  • Research Products

    (77 results)
  • Co-Researchers

    (47 People)
  •  Novel treatment using adipose stem cell for postoperative liver damage

    • Principal Investigator
      ONOE Shunsuke
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nagoya University
  •  Novel therapy based on engraftment, asymmetric division and Self-organization of circulating tumor cells

    • Principal Investigator
      相場 利貞
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nagoya University
  •  Novel diagnostic methods for invisible pancreas cancer

    • Principal Investigator
      WATANABE Nobuyuki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nagoya University
  •  The role of Trefoil Factors in hepato-carcinogenesis

    • Principal Investigator
      Ebata Tomoki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nagoya University
  •  Novel nucleic acid medicine for the fusion genes in cholangiocarcinomaPrincipal Investigator

    • Principal Investigator
      Nagino Masato
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Aichi Cancer Center Research Institute
      Nagoya University
  •  Novel therapy for cancer using deep ultraviolet

    • Principal Investigator
      Miyata Kazushi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nagoya University
  •  The mechanisms of cancer development from Barrett esophagus regarding Trefoil Factors.

    • Principal Investigator
      Fukaya Masahide
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nagoya University
  •  Development of real-time navigation system for hepatectomy

    • Principal Investigator
      IGAMI TSUYOSHI
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nagoya University
  •  The role of TFF1 to inhibit the development of pancreatic cancer

    • Principal Investigator
      Yamaguchi Junpei
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  術後肝障害に対するTLR4を標的にした予防治療法の開発

    • Principal Investigator
      菅原 元
    • Project Period (FY)
      2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Novel strategies for cancer stem cells

    • Principal Investigator
      TSUNODA NOBUYUKI
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nagoya University
  •  Mechanism of a new cancer treatment targeting TLR7

    • Principal Investigator
      UEHARA KEISUKE
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Analysis of the inhibitory effect of cysteine on liver damage

    • Principal Investigator
      YOKOYAMA YUKIHIRO
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Novel strategies to target the premetastatic niche for cancer metastasis

    • Principal Investigator
      MIZUNO TAKASHI
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Mechanism of action of a bisabolol derivative and its clinical application

    • Principal Investigator
      KOKURYO TOSHIO
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Novel strategies targeting RAGE for postoperative infectious complications

    • Principal Investigator
      FUKAYA MASAHIDE
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Novel treatment for chromothripsis in breast cancer

    • Principal Investigator
      Tsunoda Nobuyuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nagoya University
  •  Novel strategies for endogenous danger signals by a TLR7 aptamer

    • Principal Investigator
      Uehara Keisuke
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Analysis of a new molecular system of branched-chain amino acids in liver damage following ischemia and re-perfusion

    • Principal Investigator
      Sugawara Gen
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Functional analysis of novel genes based on molecular evolution

    • Principal Investigator
      Yokoyama Yukihiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Novel inhibitor of serine threonine kinase for the treatment of cholangiocarcinoma and pancreas cancerPrincipal Investigator

    • Principal Investigator
      Nagino Masato
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  化学療法関連肝障害の外科手術への影響とその病態生理の解明

    • Principal Investigator
      YOSHIOKA YUICHIRO
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Novel strategy for the gene concerning chemoresistance in pancreas cancer

    • Principal Investigator
      KOKURYO TOSHIO
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Development of the monitoring system for the liver function in hepatectomyPrincipal Investigator

    • Principal Investigator
      NAGINO Masato
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Analysis of novel Hedgehog inhibitors for esophageal cancer

    • Principal Investigator
      FUKAYA MASAHIDE
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Analysis of Oncogene-induced-Senescence related genes in cancer for clinical application

    • Principal Investigator
      IGAMI TSUYOSHI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Novel cancer therapy based ongene profiling in micrometastasis

    • Principal Investigator
      TSUNODA Nobuyuki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nagoya University
  •  Analysis of immunity induction in rectal cancer in association with microscopic abscess formation

    • Principal Investigator
      UEHARA Keisuke
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  MRM・MS and microRNA profiling analyses of blood samples and their clinical applications for development of molecular diagnostics

    • Principal Investigator
      TAKAHASHI Takashi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  GGTトランスジェニックマウスを用いた肝虚血/再潅流障害メカニズムの解明

    • Principal Investigator
      菅原 元
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Comprehensive cancer therapy targeted Nek2 and translational research

    • Principal Investigator
      NIMURA Yuji
    • Project Period (FY)
      2008 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Digestive surgery
    • Research Institution
      Aichi Cancer Center Research Institute
  •  The role of calcitonin in the early phase of liver regeneration and its molecular mechanism.

    • Principal Investigator
      YOKOYAMA Yukihiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  The role of PPARγ in bile duct ligation-induced hepatic injury in rats.

    • Principal Investigator
      EBATA Tomoki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  The development of the novel treatment that targeted plural cancer specific genes

    • Principal Investigator
      KOKURYO Toshio
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Molecule targeted therapy for Cholangiocarcinoma based on the gene profiling of cancer stem cellPrincipal Investigator

    • Principal Investigator
      NAGINO Masato
    • Project Period (FY)
      2007 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  The effects of renal failure on hepatic regeneration following hepatectomy

    • Principal Investigator
      NISHIO Hideki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  The Role of Hedgehog Signaling in the Development of Cholangiocarcinoma

    • Principal Investigator
      ABE Tetsuya
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Aichi Cancer Center Research Institute
      Nagoya University
  •  Tailor-made cancer diagnosis by systematically detecting alterations of miRNA and protein expressions

    • Principal Investigator
      TAKASHI Takahashi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  Development of the new treatment that targeted mammary cancer stem cell

    • Principal Investigator
      ODA Koji
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nagoya University
  •  化学発癌が疑われるインドの胆嚢癌の発生機序の解明と早期診断に関する国際共同研究

    • Principal Investigator
      小田 高司
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  The role of PPARy in bile duct ligation-induced hepatic injury in rats

    • Principal Investigator
      YOKOYAMA Yukihiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  The mechanism of liver regeneration in response to continuous stretch in ECs

    • Principal Investigator
      NISHIO Hideki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  The Profiling of Cholangiocarcinoma and the Development of Molecular targeted therapy

    • Principal Investigator
      NIMURA Yuji
    • Project Period (FY)
      2004 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Digestive surgery
    • Research Institution
      Aichi Cancer Center Research Institute
      Nagoya University
  •  The Research and Development of Gene Therapy for Breast Cancer by Src Signal Tiansduction Pathways

    • Principal Investigator
      ODA Koji
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nagoya University
  •  Biological modulation of steroid for bile output

    • Principal Investigator
      YUASA Norihiro, 西尾 秀樹
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nagoya University
  •  Experimental study on mechanism of liver regeneration with special attention to continuous stretch in endothelial cellsPrincipal Investigator

    • Principal Investigator
      NAGINO Masato
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Effects of biliary drainage on the impaired functions of organs and immunity in obstructive cholestasis

    • Principal Investigator
      ARAI Toshiyuki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Clinical and experimental study of regeneration of nonembolized lobe after portal vein embolizationPrincipal Investigator

    • Principal Investigator
      NAGINO Masato
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  An experimental and clinical study of selective intrahepatic biliary ablatron with absolute ethanol

    • Principal Investigator
      KAMIYA Junichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  FUNCTIONAL ANALYSIS OF P73 GENE AND P51/P63 GENE IN HUMAN MAMMARY TISSUE AND MAMMARY CARCINOMA

    • Principal Investigator
      ODA Koji
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nagoya University
  •  Experimental study on effect of preconditioning to hepatic ischemia/reperfusion injury.Principal Investigator

    • Principal Investigator
      NAGINO Masato
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Study of molecular pathology for intestinal stasis-associated bowel diseases

    • Principal Investigator
      UESAKA Katsuhiko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  promoting mechanism of lithocholic acid in colon carcinogenesis induced by monomethylating agents

    • Principal Investigator
      KAMIYA Junichi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  New vector system for the gene therapy of abdominal cancers.

    • Principal Investigator
      NIMURA Yuji
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  安全な広範肝切除を目的とした門脈枝塞栓術の基礎的および臨床的研究Principal Investigator

    • Principal Investigator
      NAGINO Masato
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Basic and clinical study for posthepatectomy liverfailure associated with bacterial infection

    • Principal Investigator
      KAMIYA Junichi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Basic and clinical studies asociated with hepatic reticulo endothelial system after major surgery

    • Principal Investigator
      NIMURA Yuji
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Basic and Clinical Studies for the Relationship between Multiple Organ Failure and Intestinal Mucosal Injury.

    • Principal Investigator
      MIYACHI Masahiko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      NAGOYA UNIVERSITY
  •  Clinical and experimental studies on the liver cell damage under segmental cholestasis

    • Principal Investigator
      KAMIYA Junichi, 金井 道夫
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University
  •  Experomental and clinical studies to increase curability and safety of surgery for hilar cholangiocarcinoma

    • Principal Investigator
      NIMURA Yuji
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Digestive surgery
    • Research Institution
      Nagoya University

All 2021 2020 2019 2018 2017 2015 2013 2012 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

  • [Journal Article] Trefoil factor family 2 inhibits cholangiocarcinogenesis by regulating the PTEN pathway in mice2021

    • Author(s)
      Keiji Hasebe, Junpei Yamaguchi, Toshio Kokuryo, Yukihiro Yokoyama, Yosuke Ochiai, Masato Nagino and Tomoki Ebata
    • Journal Title

      Carcinogenesis

      Volume: 42 (12) Pages: 1496-1505

    • DOI

      10.1093/carcin/bgab093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09141
  • [Journal Article] Trefoil Factor Family 1 Inhibits the Development of Hepatocellular Carcinoma by Regulating β-Catenin Activation2020

    • Author(s)
      Ochiai Y, Yamaguchi J, Kokuryo T, Yokoyama Y, Ebata T, Nagino M
    • Journal Title

      Hepatology

      Volume: - Pages: 503-517

    • DOI

      10.1002/hep.31039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09141
  • [Journal Article] Trefoil Factor 1 inhibits epithelial-mesenchymal transition of pancreatic intraepithelial neoplasm.2018

    • Author(s)
      Yamaguchi J, Yokoyama Y, Kokuryo T, Ebata T, Enomoto A, Nagino M.
    • Journal Title

      Journal of Clinical Investigation

      Volume: 128(8) Pages: 3619-3629

    • DOI

      10.1172/jci97755

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10695
  • [Journal Article] Trefoil factor family 1 expression in the invasion front is a poor prognostic factor associated with lymph node metastasis in pancreatic cancer2017

    • Author(s)
      Masaki Sunagawa, Junpei Yamaguchi, Toshio Kokuryo, Tomoki Ebata, Yukihiro Yokoyama, Gen Sugawara, Masato Nagino
    • Journal Title

      Pancreatology

      Volume: 17 (5) Pages: 782-787

    • DOI

      10.1016/j.pan.2017.07.188

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10695
  • [Journal Article] Hepatectomy with simultaneous resection of the portal vein and hepatic artery for advanced perihilar cholangiocarcinoma : an audit of 50 consecutive cases.2010

    • Author(s)
      Nagino M, Nimura Y, Kamei Y., (他7名)
    • Journal Title

      Ann Surg. 252(1)

      Pages: 115-123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] A Novel Combination Treatment for Colorectal Cancer using Nek2 siRNA and Cisplatin2010

    • Author(s)
      Kazushi Suzuki, Toshio Kokuryo, Takeshi Senga, Yukihiro Yokoyama, Masato Nagino, Michinari Hamaguchi
    • Journal Title

      Cancer Science (In press)

    • NAID

      10026592095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591624
  • [Journal Article] 15-deoxy-delta 12,14-prostaglandin J2 prevents inflammatory response and endothelial cell damage in rats with acute obstructive cholangitis.2010

    • Author(s)
      Watanabe K, Yokoyama Y, Nagino M., (他7名)
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol. 298(3)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] Silencing of Tousled-like kinase 1 sensitizes cholangiocarcinoma cells to cisplatin-induced apoptosis.2010

    • Author(s)
      Takayama Y, Kokuryo T, Yokoyama Y, Ito S, Nagino M, Hamaguchi M, Senga T.
    • Journal Title

      Cancer Lett.

      Volume: 296(1) Pages: 27-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249062
  • [Journal Article] Value of indocyanine green clearance of the future liver remnant in predicting outcome after resection for biliary cancer.2010

    • Author(s)
      Yokoyama Y, Sugawara G, Nagino M., (他5名)
    • Journal Title

      Br J Surg. 97(8)

      Pages: 1260-1268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] 15-deoxy-delta12,14-prostaglandin J2 prevents inflammatory response and endothelial cell damage in rats with acute obstructive cholangitis.2010

    • Author(s)
      Watanabe K, Yokovama Y, Kokuryo T, Kawai K, Kitagawa T, Seki T, Nakagawa A, Nagino M.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 298(3)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591608
  • [Journal Article] Inchinkoto, an herbal medicine, exerts beneficial effects in the rat liver under stress with hepatic ischemia-reperfusion and subsequent hepatectomy.2010

    • Author(s)
      Kawai K, Kokuryo T, Nagino M., (他5名)
    • Journal Title

      Ann Surg. 251(4)

      Pages: 692-700

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] Novel combination treatment for colorectal cancer using Nek2 siRNA and cisplatin.2010

    • Author(s)
      Suzuki K, Kokuryo T, Nagino M
    • Journal Title

      Cancer Sci.

      Volume: 101(5) Pages: 1163-1169

    • NAID

      10026592095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] Novel combination treatment for colorectal cancer using Nek2 siRNA and cisplatin.2010

    • Author(s)
      Suzuki K, Kolcuryo T, Nagino M
    • Journal Title

      Cancer Sci.

      Volume: 101(5) Pages: 1163-9

    • NAID

      10026592095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591624
  • [Journal Article] Silencing of Tousled-like kinase 1 sensitizes cholangiocazcinoma cells to cisplatin-induced apoptosis.2010

    • Author(s)
      Takayama Y, Kokuryo T, Nagino M., 他6名
    • Journal Title

      Cancer Lett.

      Volume: 296(1) Pages: 27-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591624
  • [Journal Article] Silencing of Tousled-like kinase 1 sensitizes cholangiocarcinoma cells to cisplatin-induced apoptosis.2010

    • Author(s)
      Takayama Y, Kokuryo T, Nagino M., 他6名
    • Journal Title

      Cancer Lett.296(1):27-34.2010

      Volume: 296(1) Pages: 27-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] Inchinkoto, an herbal medicine, exerts beneficial effects in the rat liver under stress with hepatic ischemia-reperfusion and subsequent hepatectomy.2010

    • Author(s)
      Kawai K, Kokuryo T, Nagino M.
    • Journal Title

      Ann Surg. 251(4), 249(2)

    • Data Source
      KAKENHI-PROJECT-20591624
  • [Journal Article] Hepatectomy with simultaneous resection of the portal vein and hepatic artery for advanced perihilar cholangiocarcinoma : an audit of 50 consecutive cases.2010

    • Author(s)
      Nagino M, Nimura Y, Kamei Y., 他7名
    • Journal Title

      Ann Surg.

      Volume: 252(1) Pages: 115-123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] Novel combination treatment for colorectal cancer using Nek2 siRNA and cisplatin2010

    • Author(s)
      Suzuki K, Kokuryo T, Senga T, Yokoyama Y, Nagino M, Hamaguchi M.
    • Journal Title

      Cancer Sci.

      Volume: 101(5) Pages: 1163-1169

    • NAID

      10026592095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249062
  • [Journal Article] Gemcitabine alone or in combination with cisplatin in patients with biliary tract cancer: a comparative multicentre study in Japan.2010

    • Author(s)
      Okusaka T, Nakachi K, Fukutomi A, Mizuno N, Ohkawa S, Funakoshi A, Nagino M, Kondo S, Nagaoka S, Funai J, Koshiji M, Nambu Y, Furuse J, Miyazaki M, Nimura Y.
    • Journal Title

      Br J Cancer.

      Volume: 103(4) Pages: 469-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249062
  • [Journal Article] Nek2 as a novel molecular target for the treatment of breast carcinoma.2009

    • Author(s)
      Tsunoda N, Kokuryo T, Nagino M.
    • Journal Title

      Cancer Sci. 100(1)

      Pages: 111-116

    • NAID

      10025141544

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591624
  • [Journal Article] Clinicopathologic study of cholangiocarcinoma with superficial spread.2009

    • Author(s)
      Igami T, Nagino M, Yokoyama Y, (他4名)
    • Journal Title

      Ann Surg. 249(2)

      Pages: 296-302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] Nek2 as a novel molecular target for the treatment of breast carcinoma.2009

    • Author(s)
      Tsunoda N, Kokuryo T, Nagino M., (他4名)
    • Journal Title

      Cancer Sci. 100(1)

      Pages: 111-116

    • NAID

      10025141544

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] ESTROGEN PROMOTES HEPATIC REGENERATION VIA ACTIVATING2009

    • Author(s)
      Kitagawa T, Yokoyama Y, Kokuryo T, Kawai T, Watanabe K, Kawai K, Nagino M
    • Journal Title

      SEROTONIN SIGNAL (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591582
  • [Journal Article] let-7 regulates Dicer expression and constitutes a negative feedback loop2008

    • Author(s)
      Tokumaru, S., Suzuki, M., Yamada, H., Nagino, N. and Takahashi, T.
    • Journal Title

      Carcinogenesis 29

      Pages: 2073-2077

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390171
  • [Journal Article] Recent advances in treatment of hilar cholangiocarcinoma : Portal vein embolization.2007

    • Author(s)
      Yokoyama Y, Nagino M, Nimura Y., (他5名1)
    • Journal Title

      J HPB Surg. 14

      Pages: 447-454

    • NAID

      10019811065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] CLCP1 interacts with semaphoring 4B and regulates motility of lung cancer cells.2007

    • Author(s)
      Nagai H, Nagino M, Nimura Y, (他7名)
    • Journal Title

      Oncogene 26

      Pages: 4025-4031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] Mechanism of impaired hepatic regeneration in cholestatic liver.2007

    • Author(s)
      Yokoyama Y, Nagino M, Nimura Y.
    • Journal Title

      J Hepatobiliary Pancreat Surg. 14

      Pages: 159-166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] Is there any effect of renal failure on the hepatic regeneration capacity following partial hepatectomy in rats?2007

    • Author(s)
      Kawai T, Yokoyama Y, Nagino M, (他2名)
    • Journal Title

      Biochem Biophys Res Commun. 352

      Pages: 311-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] Nek2 as an effective target for inhibition of tumorigenic growth and peritoneal dissemination of cholangiocarcinoma.2007

    • Author(s)
      Kokuryo T, Senga T, Yokoyama Y, Nagino M, Nimura Y, Hamaguchi M.
    • Journal Title

      Cancer Res 67

      Pages: 9637-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16209039
  • [Journal Article] Nek2 as effective target for inhibition of tumorigenic growth and peritoneal dissemination of cholangiocarcinoma.2007

    • Author(s)
      Kokuryo T, Senga T, Yokoyama Y, Nagino M, Nimura Y, Hamaguchi M.
    • Journal Title

      Cancer Research 67

      Pages: 9637-42

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209039
  • [Journal Article] Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92.2007

    • Author(s)
      Matsubara H, Nagino M, Nimura Y, (他9名)
    • Journal Title

      Oncogene 26(41)

      Pages: 6099-6105

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] Nek2 as an affective target for inhibition of tumorigenic growth and peritoneal dissemination of cholangiocarcinoma.2007

    • Author(s)
      Kokuryo T, Yokoyama Y, Nagino M, (他3名)
    • Journal Title

      Cancer Research 67(20)

      Pages: 9637-9642

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Journal Article] Mechanotransduction by integrin is essential for IL-6 secretion from endothelial cells in response to uniaxial continuous stretch2005

    • Author(s)
      Sasamoto A, Nagino M, et al.
    • Journal Title

      American Journal of Physiology- Cell Physiology (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591398
  • [Journal Article] Mechanotransduction by integrin is essential for IL-6 secretion from endothelial cells in response to uniaxial continuous stretch2005

    • Author(s)
      Sasamoto A, Nagino M, et al.
    • Journal Title

      American Journal of Physiology-Cell Physiology (in press)

    • Data Source
      KAKENHI-PROJECT-15591398
  • [Journal Article] One hundred consecutive hepatobiliary resections for biliary hilar malignancy2005

    • Author(s)
      Nagino M, et al.
    • Journal Title

      Surgery 137

      Pages: 148-155

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591398
  • [Journal Article] One hundred consecutive hepatobiliary resections for biliary hilar malignancy : preoperative blood donation, blood loss, transfusion, and outcome.2005

    • Author(s)
      Nagino M, Kamiya J, Arai T, Nishio H, Ebata T, Nimura Y.
    • Journal Title

      Surgery 137

      Pages: 148-155

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591398
  • [Journal Article] Changes in splenic volume during liver regeneration.2004

    • Author(s)
      Ando H, Nagino M, Arai T, Nishio H, Nimura Y.
    • Journal Title

      World J Surg 28

      Pages: 977-981

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591398
  • [Journal Article] Changes in splenic volume during liver regeneration2004

    • Author(s)
      Ando H, Nagino M, et al.
    • Journal Title

      World Journal of Surgery 28

      Pages: 977-981

    • Data Source
      KAKENHI-PROJECT-15591398
  • [Journal Article] Changes in splenic volume during liver regeneration2004

    • Author(s)
      Ando H, Nagino M, et al.
    • Journal Title

      World Journal of Sugrery 28

      Pages: 977-981

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591398
  • [Journal Article] Stretch-induced IL-6 secretion from endothelial cells requires NF-κB activation2003

    • Author(s)
      Kobayashi S, Nagino M, et al.
    • Journal Title

      Biochemical and Biophysical Research Communications 308

      Pages: 316-312

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591398
  • [Journal Article] Most informative projection for portography : Quantitative analysis of 47 percutaneous transhepatic portograms.2003

    • Author(s)
      Nishio H, Nagino M, Kamiya J, Uesaka K, Oda K, Sano T, Kanai M, Nimura Y.
    • Journal Title

      World J Surg 27

      Pages: 433-436

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591398
  • [Journal Article] Most informative projection for portography2003

    • Author(s)
      Nishio H, Nagino M, et al.
    • Journal Title

      World Journal of Surgery 27

      Pages: 433-436

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591398
  • [Journal Article] Loss of p27kip1 accelerates DNA replication after partial hepatectomy in mice2003

    • Author(s)
      Hayashi E, Nagino M, et al.
    • Journal Title

      Journal of Surgical Research 111

      Pages: 196-202

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591398
  • [Journal Article] Stretch-induced IL-6 secretion from endothelial cells requires NF-κB activation.2003

    • Author(s)
      Kobayashi S, Nagino M, Komatsu S, Naruse K, Nimura Y, Nakanishi M, Sokabe M.
    • Journal Title

      BBRC 308

      Pages: 306-312

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591398
  • [Journal Article] Loss of p27kip1 accelerates DNA replication after partial hepatectomy in mice.2003

    • Author(s)
      Hayashi E, Yasui A, Oda K, Nagino M, Nimura Y, Nakanishi M, Motoyama N, Ikeda K.
    • Journal Title

      J Surg Res 111

      Pages: 196-202

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591398
  • [Journal Article] Mechanotransduction by integrin is essential for IL-6 secretion from endothelial cells in response to uni-axial continuous stretch.

    • Author(s)
      Sasamoto A, Nagino M, Kobayashi S, Naruse K, Nimura Y, Sokabe M.
    • Journal Title

      Am J Physiol-Cell Physiology- (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591398
  • [Presentation] Trefoil Factor Family 1 Inhibits the Development of Hepatocellular Carcinoma by Regulating β-Catenin Activation.2019

    • Author(s)
      Ochiai Y, Yamaguchi J, Kokuryo T, Yokoyama Y, Ebata T, Nagino M
    • Organizer
      The Liver Meeting 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09141
  • [Presentation] Trefoil Factor Family 1 (TFF1) Inhibits Epithelial-mesenchymal Transition and Enhances the Chemosensitivity of Pancreatic Ductal Adenocarcinoma (PDAC)2019

    • Author(s)
      J Yamaguchi, T Kokuryo, Y Yokoyama, T Ebata, and M Nagino
    • Organizer
      APA annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10695
  • [Presentation] 2-Hydroxypropyl-beta-cyclodextrin encapsulated α-bisabolol (CD-BSB) improves the antitumor effect of α-bisabolol for pancreatic cancer2018

    • Author(s)
      Taisuke Baba, Toshio Kokuryo , Yukihiro Yokoyama, Junpei Yamaguchi, Masato Nagino
    • Organizer
      the AACR’s fifth Pancreatic Cancer Special Conference: Advances in Science and Clinical Care
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10591
  • [Presentation] Trefoil Factor 1 inhibits epithelial-mesenchymal transition (EMT) of pancreatic intraepithelial neoplasm.2018

    • Author(s)
      Junpei Yamaguchi, Yukihiro Yokoyama, Toshio Kokuryo and Masato Nagino
    • Organizer
      AACR Pancreatic cancer: advances in science and clinical care
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10695
  • [Presentation] Preserved expression of TFF1 in invasive front is a poor prognostic factor in PDAC2017

    • Author(s)
      Junpei Yamaguchi, Masaki Sunagawa, Yukihiro yokoyama, Toshio Kokuryo, Tomoki Ebata, Masato Nagino
    • Organizer
      Joint Congress of The 6th Biennial Congress of the Asian-Pacific Hepato-Pancreato-Biliary Association & The 29th Meeting of Japanese Society of Hepato-Biliary-Pancreatic Surgery
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10695
  • [Presentation] 遺伝子改変マウスを用いたTFF1欠損による膵浸潤癌発生に関する検討2017

    • Author(s)
      山口淳平、江畑智希、横山幸浩、國料俊男、梛野正人
    • Organizer
      第48回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-17K10695
  • [Presentation] Targeting protein for Xklp2(TPX2)を標的にした膵癌治療法の開発2015

    • Author(s)
      三輪 知弘, 國料 俊男, 横山 幸浩, 山口 淳平, 梛野 正人
    • Organizer
      第115回日本外科学会定期学術集会
    • Place of Presentation
      愛知県名古屋市. 名古屋国際会議場
    • Year and Date
      2015-04-16
    • Data Source
      KAKENHI-PROJECT-24592023
  • [Presentation] The expression pattern of MyD88 in rectal cancer in association with microscopic abscess formation.2013

    • Author(s)
      Masanori Uno, Toshio Kokuryo, Yukihiro Yokoyama, Keisuke Uehara, Yuichiro Yoshioka, Masato Nagino
    • Organizer
      Ninth AACR Japanese Cancer Association Joint Conference
    • Place of Presentation
      Maui, USA
    • Data Source
      KAKENHI-PROJECT-22591483
  • [Presentation] The expression pattern of MyD88 in rectal cancer in association with microscopic abscess formation2013

    • Author(s)
      Masanori Uno, Toshio Kokuryo, Yukihiro Yokoyama, Keisuke Uehara, Yuichiro Yoshioka, Masato Nagino
    • Organizer
      Ninth AACR Japanese Cancer Association Joint Conference
    • Place of Presentation
      Maui, USA
    • Data Source
      KAKENHI-PROJECT-22591483
  • [Presentation] The combination treatments using siRNA and CDDP are effective therapeutic options for cancers.2012

    • Author(s)
      T Kokuryo, Y Yokoyama, K Suzuki, T Ebata, N Tsunoda, T Igami, G Sugawara, M Fukaya, Y Takahashi, K Uehara, Y Yoshioka, M Nagino.
    • Organizer
      AACR 102nd annual meeting
    • Place of Presentation
      Orange County Convention Center (Orlando, USA)
    • Year and Date
      2012-04-04
    • Data Source
      KAKENHI-PROJECT-20249062
  • [Presentation] The efficiency of Nek2 siRNAfor liver metastasis of pancreatic cancer2012

    • Author(s)
      Kokuryo T, Yokoyama Y, Nagino M.
    • Organizer
      AACR 103rd annual meeting
    • Place of Presentation
      McCormick Place (Chicago, USA)
    • Year and Date
      2012-04-01
    • Data Source
      KAKENHI-PROJECT-20249062
  • [Presentation] Nek2 siRNAの非臨床試験と臨床応用2012

    • Author(s)
      國料俊男, 横山幸浩, 江畑智希, 菅原 元, 高橋 祐, 伊神 剛, 深谷昌秀, 上原圭介, 板津慶太, 吉岡裕一郎, 梛野正人
    • Organizer
      第67回 日本消化器外科学会総会
    • Place of Presentation
      富山国際会議場(富山)
    • Year and Date
      2012-07-19
    • Data Source
      KAKENHI-PROJECT-20249062
  • [Presentation] Nek2 as an effective molecular target for cancer treatment.2010

    • Author(s)
      Kokuryo T, Senga T, Yokoyama Y, Nagino M, Hamaguchi M.
    • Organizer
      AACR 101st annual meeting.
    • Place of Presentation
      Walter E. Washington Convention Center (Washington DC, USA)
    • Year and Date
      2010-04-19
    • Data Source
      KAKENHI-PROJECT-20249062
  • [Presentation] Nek2 as an effective molecular target for cancer treatment2010

    • Author(s)
      Kokuryo T, Senga T, Yokoyama Y, Nagino M, Hamaguchi M.
    • Organizer
      AACR 101^<st>annual meeting
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-20591624
  • [Presentation] Nek2 as an effective molecular target for cancer treatment2010

    • Author(s)
      Kokuryo T, Senga T, Yokoyama Y, Nagino M, Hamaguchi M.
    • Organizer
      AACR 101^<st> annual meeting
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Presentation] siRNAを用いた癌分子標的治療のトランスレーショナルリサーチ2010

    • Author(s)
      國料俊男、横山幸浩、梛野正人
    • Organizer
      JDDW 2010
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20591624
  • [Presentation] siRNAを用いた癌分子標的治療のトランスレーショナルリサーチ2010

    • Author(s)
      國料俊男、横山幸浩、梛野正人
    • Organizer
      JDDW 2010
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-20249062
  • [Presentation] Nek2 as an effective molecular target for cancer treatment2010

    • Author(s)
      Kokuryo T, Senga T, Yokoyama Y, Nagino M, Hamaguchi M.
    • Organizer
      AACR 101^<st> annual meeting
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-20249062
  • [Presentation] siRNAを用いた癌分子標的治療のトランス2010

    • Author(s)
      國料俊男、横山幸浩、梛野正人
    • Organizer
      レーショナルリサーチJDDW2010
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Presentation] siRNAを用いた癌分子標的治療のトランスレーショナルリサーチ2010

    • Author(s)
      國料俊男、横山幸浩、梛野正人
    • Organizer
      JDDW 2010
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19390348
  • [Presentation] siRNAを用いた癌分子標的治療のトランスレーショナルリサーチ2010

    • Author(s)
      國料俊男、横山幸浩、梛野正人
    • Organizer
      JDDW 2010
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20249062
  • [Presentation] Nek2 as an effective molecular target for cancer treatment2010

    • Author(s)
      Kokuryo T, Senga T, Yokoyama Y, Nagino M, Hamaguchi M
    • Organizer
      AACR 101^<st> annual meeting
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2010-04-19
    • Data Source
      KAKENHI-PROJECT-20591624
  • [Presentation] 肝内結石症の網羅的遺伝子解析より始まった癌分子標的治療の開発2009

    • Author(s)
      國料俊男、横山幸浩、菅原元、江畑智希、西尾秀樹、梛野正人
    • Organizer
      日本肝胆膵外科学会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-06-10
    • Data Source
      KAKENHI-PROJECT-20591624
  • [Presentation] 15-Deoxy-A^<12>,^<14>-Prostaglandin J2 prevents the inflammatory response and improves the survival in rats with acute obstructive cholangitis2009

    • Author(s)
      Yukihiro Yokovama, Katsutaka Watanabe, Toshio Kokurvo, Kiyotaka Kawai, Tomomi Kitagawa, Takashi Seki, Akifumi Nakagawa, Masato Nagino.
    • Organizer
      60 th American association for the study of liver diseases
    • Place of Presentation
      Boston
    • Year and Date
      2009-11-01
    • Data Source
      KAKENHI-PROJECT-20591608
  • [Presentation] The mechanism of protective effects of PPARγ activation on bile duct ligation-induced hepatic injury in rats2009

    • Author(s)
      Tomomi Kitagawa, Yukihiro Yokovama, Toshio Kokurvo, Kiyotaka Kawai, Katsutaka Watanabe, Masato Nagino.
    • Organizer
      60 th American association for the study of liver diseases
    • Place of Presentation
      Boston
    • Year and Date
      2009-11-01
    • Data Source
      KAKENHI-PROJECT-20591608
  • [Presentation] The development of novel therapy for Cholangiocarcinoma By usage of Nek2 siRNA2007

    • Author(s)
      Kokuryo T, Hibino S, Takayama Y, Kawai T, Oda K, Yokoyama Y, Nagino M, Nimura Y.
    • Organizer
      The 62th Annual Meeting of Japanese Society of Gastroenterological Surgery
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-07-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209039
  • [Presentation] The efficency of Nek2 siRNA for peritoneal dissemination2007

    • Author(s)
      Kokuryo T, Igami T, Ebata T, Nishio H, Nagino M, Nimura Y.
    • Organizer
      The 107th Annual Meeting of Japan Surgical Society
    • Place of Presentation
      Osaka
    • Year and Date
      2007-04-13
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209039
  • [Presentation] Expression of p63 is a useful indicator of poor prognosis after resection in adenocarcinomas of the gallbladder and pancreas2006

    • Author(s)
      Tatsuyoshi Yamamoto, Koji Oda, Hideo Yamamoto, Naokazu Hayakawa, Masato Nagino, Yuji Nimura
    • Organizer
      7^<th> World congress of IHPBA
    • Place of Presentation
      Edinburgh, Scotland
    • Year and Date
      2006-09-06
    • Data Source
      KAKENHI-PROJECT-18591436
  • [Presentation] The profiling of Cholangiocarcinoma and the development of molecular Targeted therapy by usage of Nek2 siRNA2005

    • Author(s)
      Kokuryo T, Oda K, Ebata T, Nishio H, Arai T, Yuasa N, Nagino M, Nimura Y.
    • Organizer
      The 17th Annual Meeting of Japanese Society of Hepato-Billiary-Pancreatic Surgery
    • Place of Presentation
      Yokohama
    • Year and Date
      2005-06-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209039
  • [Presentation] The efficiency of Nek2 siRNA for liver metastasis of pancreatic cancer

    • Author(s)
      Kokuryo T, Yokoyama Y, Nagino M.
    • Organizer
      AACR annual meeting
    • Place of Presentation
      McCormick Place (Chicago)
    • Data Source
      KAKENHI-PROJECT-20249062
  • [Presentation] Nek2 siRNAの非臨床試験と臨床応用

    • Author(s)
      國料俊男,横山幸浩,江畑智希,菅原 元,高橋 祐,伊神 剛,,深谷昌秀,上原圭介,板津慶太,吉岡裕一郎,梛野正人
    • Organizer
      第67回 日本消化器外科学会総会
    • Place of Presentation
      富山国際会議場(富山)
    • Data Source
      KAKENHI-PROJECT-20249062
  • 1.  KOKURYO Toshio (60378023)
    # of Collaborated Projects: 35 results
    # of Collaborated Products: 46 results
  • 2.  YOKOYAMA Yukihiro (80378091)
    # of Collaborated Projects: 35 results
    # of Collaborated Products: 43 results
  • 3.  NIMURA Yuji (80126888)
    # of Collaborated Projects: 23 results
    # of Collaborated Products: 13 results
  • 4.  Yamaguchi Junpei (00566987)
    # of Collaborated Projects: 16 results
    # of Collaborated Products: 10 results
  • 5.  KAMIYA Junichi (70194975)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 0 results
  • 6.  ODA Koji (30311715)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 5 results
  • 7.  EBATA Tomoki (60362258)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 5 results
  • 8.  NISHIO Hideki (30345897)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 4 results
  • 9.  KANAI Michio (50242871)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 10.  YUASA Norihiro (00303610)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 11.  ARAI Toshiyuki (80335041)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 3 results
  • 12.  ABEA Tetsuy (90378092)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 5 results
  • 13.  UEHARA Keisuke (50467320)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 2 results
  • 14.  MIYACHI Katsuhiko (20283434)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 15.  MIYACHI Masahiko (80242874)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 16.  SUGAWARA Gen (00402587)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 17.  HAMAGUCHI Michinari (90135351)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 18.  IGAMI TSUYOSHI (50420378)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 19.  FUKAYA MASAHIDE (10420382)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 20.  KONDO Satoshi (30215454)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 21.  GOTO Hidemi (10215501)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 22.  SENGA Takeshi (80419431)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 23.  TSUNODA Nobuyuki (40542684)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 24.  TAKASHI Takahashi (50231395)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 25.  YANAGISAWA Kiyoshi (20372112)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 26.  MITSUDOMI Tetsuya (70209807)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 27.  SANO Tsuyoshi (60303632)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 28.  YATABE Yasushi (90280809)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 29.  YOSHIOKA YUICHIRO (50597854)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 30.  ITATSU Keita (90534842)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 31.  TOMIDA Shuta (10372111)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  HIDA Toyoaki (80250249)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  ARIMA Chinatsu (00534843)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  MATSUO Keitaro (80393122)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  ISHIGURO Seiji (50571345)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  SHIMIZU Yasuhiro (40470166)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  YOSHIKAI Yasunobu (90158402)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  HAGIWARA Masatoshi (10208423)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  MATSUDA Satoru (50242110)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  MIZUNO TAKASHI (90444413)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  Miyata Kazushi (90752759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  ONOE Shunsuke (20807515)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  WATANABE Nobuyuki (20746903)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  竹腰 進 (70216878)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  宇都宮 洋才 (60264876)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  相場 利貞 (60789569)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  KITAGAWA TOMOMI
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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