NAGASHIMA Tadashi 長島正

Researcher Number	70217991
Other IDs
External Links
Affiliation (based on the past Project Information) *help	1995 – 2005: 帝京大学, 医学部, 教授 1993 – 1994: 帝京大学, 医学部, 助教授 1990 – 1993: 東京大学, 医学部(病), 助手 1992: 東京大学, 医学部(病)脳神経外科, 助手 1991: 東京大学医学部(病), 脳神経外科, 助手 1990: 東京大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Cerebral neurosurgery Except Principal Investigator Cerebral neurosurgery / Plastic surgery / Cerebral neurosurgery
Keywords	Principal Investigator N-カドヘリン / グリオーマ / invasion / 浸潤 / 悪性グリオーマ / ヌードラット / 蛍光標識 / HGF / P53 / fibronectin … More / P53遺伝子 / 膠芽腫 / 髓芽腫 / BUdR-LI / 造腫瘍性 / グリオーマ細胞 / 細胞接着 / C-Src / 細胞接着能 / in situ hybridization / 湿潤 / 接着能 / 回転培養 / Nーカドヘリン / mーRNA / ラットグリオ-マ細胞株 / グリア系株化腫瘍細胞 / locomotion / 無血清培地 / 細胞外マトリックス / malignant glioma / cell-cell adhesion / N-cadherin / 湿潤能 / 浸潤能 / 免疫組織化学 / glioma / in vivo / nude rat / 悪性脳腫瘍 / ミスプラチン(CDDP) / 少量連続投与 / アンチセンスオリゴヌクレオチド / MAP-1AmRNA / MAP-1A / アンチセンス / 遺伝子治療 / 化学療法 / CDDP / NK活性 / 殺細胞効果 / Malignant brain tumor / Cisplatin / Low-dose / Antisense oligodeoxynucleotide / MAP-1A mRNA / MIB-1 SI / GFAP / 多発性腫瘍 / 弧発性腫瘍 / MIB-1 / ファイブロネクチン / ラミニン / 蛍光染色 / トグリオーマ株細胞 / 腫瘍細胞浸潤 / U251MG / U87MG / fast blue / MIB-1SI / GEAP … More Except Principal Investigator GFP / グリオーマ / ニューロナビゲーター / アポトーシス / apoptosis / antisense oligonucleotide / 成長ホルモン / SNAP-25 / syntaxin / rab3B / chromogranin A / secretogranin 3 / carboxypeptidase E / phogrin / 生検 / 3次元CT / ベスナリノン / 分化誘導 / GFAP / Fi-67 / Ley / 癌遺伝子 / vErbB / 同調化化学放射線療法 / GーCSF / LAK療法 / サイトカイン / 3次元CT画像構成法 / OKT3モノクロ-ナル抗体 / 3次元画像構成 / 同調化化学放射線治療 / 発癌遺伝子 / ウィルス発癌 / 動注療法 / クリオーマ / フローサイトメトリー / 養子免疫療法 / 悪性グリオーマ / 放射線治療 / 術中照射 / 神経膠腫 / 予後規成因子 / グリオブラストーマ / 脳腫瘍 / BUdR染色 / Malignant Glioma / Radiation Therapy / Intraoperative Radiation Therapy / 局所脳虚血 / 前脳虚血 / 虚血性神経細胞死 / 遅発性神経細胞死 / 遺伝子発現 / スフィンゴミエリンサイクル / セラミド / ストレス蛋白質 / 神経栄養因子 / ラット / マウス / 蛋白代謝 / 黒質 / アセチルコリン / GAP-43 / c-myc / 脳温度 / 遠隔部 / 実質 / ischemic neuronal death / delayd neuronal death / remote neuronal damage / gene expression / MRI / sphingolipids / ceramide / 遺伝子療法 / 微小管付随蛋白 / 増殖抑制 / glioma / gene therapy / Microtubule-associated protein / growth suppression / 分泌 / 小胞輸送 / Rab3B / アンチセンス / Pituitary hormone / secretion / antisense / 仮骨延長 / 家兎 / 頭蓋形成術 / 脳損傷 / 骨延長 / latent period / calvarial distraction / rabbit / cranioplasty / brain damage / 下垂体細胞 / 分泌顆粒 / Growth hormone / pituitary cell / secretory granule Less

Study on the molecular mechanism of secretory granule formation of pituitary hormone
- Principal Investigator
  
  MATSUNO Akira
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
Study on the molecular mechanism of the secretion of pituitary hormofie
- Principal Investigator
  
  MATSUNO Akira
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
Craniofacial bone an experimental study on craniofaicial disttaction osteogenesis
- Principal Investigator
  
  HIRABAYASHI Shinichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Teikyo University
Studies on the invasive potential of malignant gliomasPrincipal Investigator
- Principal Investigator
  
  NAGASHIMA Tadashi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
Study on the practical application of chemo-radiotherapy for malignant brain tumorPrincipal Investigator
- Principal Investigator
  
  NAGASHIMA Tadashi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
Studies on a novel gene therapy of glioma using antisense oligonucletide for microtubule-associated protein mRNA
- Principal Investigator
  
  MATSUNO Akira
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
Studies on invasive properties of malignant gliomas and development of treatment modalities for these tumors.Principal Investigator
- Principal Investigator
  
  NAGASHIMA Tadashi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
悪性脳腫瘍の浸潤性増殖機構の解明とその克服に関する研究Principal Investigator
- Principal Investigator
  
  長島正
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
悪性神経膠腫に対する経口化学療法剤の開発
- Principal Investigator
  
  田中聡
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
Study of mechanism of ischemic neuronal death.a molecular biological approach
- Principal Investigator
  
  TAMURA Akira
- Project Period (FY)
  1994 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo Univ.School of Med.
悪性脳腫瘍の浸潤の評価とその克服に関する研究Principal Investigator
- Principal Investigator
  
  長島正
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
脳外科手術における3次元的手術計画および支援システムの開発
- Principal Investigator
  
  小出貢二
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
脳腫瘍(グリオーマ)における遺伝子治療の試みPrincipal Investigator
- Principal Investigator
  
  長島正
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  The University of Tokyo
Basic and Clinical Study of Radiation Therapy for Malignant Gliomas
- Principal Investigator
  
  MATSUTANI Masao
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  University of Tokyo
Quantitative Study of Invasiveness of Malignant GliomasPrincipal Investigator
- Principal Investigator
  
  NAGASHIMA Tadashi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  University of Tokyo
悪性神経膠腫のウィルス発癌と総合的治療法に関する総合的研究
- Principal Investigator
  
  TAKAKURA Kintomo
- Project Period (FY)
  1987 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  The University of Tokyo

All 2002 2001

All Journal Article

[Journal Article] Growth factor of gliomas2002
- Author(s)
  Nagashima T
- Journal Title
  
  Neurosurgery Advanced Practice (Takakura K, et al ed) (Medical View) 5
  
  Pages: 164-167
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671469
[Journal Article] 神経膠腫の成長因子2002
- Author(s)
  長島正
- Journal Title
  
  脳神経外科Advanced Practice 5
  
  Pages: 164-167
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671469
[Journal Article] Intracellular localiztion of secreted proteins and their mRNAs, detected by ultrastractural in situ hybridization method2002
- Author(s)
  Matsuno A, Nagashima T, Takekoshi S, Utunomiya H, Oosugi Y, Osamura Y
- Journal Title
  
  J of Japan Electromicroscopic Sociaty 37
  
  Pages: 85-88
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671469
[Journal Article] 腫瘍マーカー2001
- Author(s)
  長島正
- Journal Title
  
  Clinical : Neuroscience 19
  
  Pages: 307-309
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671469
[Journal Article] Tumor marker2001
- Author(s)
  Nagashima T
- Journal Title
  
  Clinical Neuroscience 19-3
  
  Pages: 307-309
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671469
[Journal Article] Confocal Laser Scaning Microscopy2001
- Author(s)
  Matsuno A, Itoh J, Nagashima T, Osamura Y, Watanabe K
- Journal Title
  
  Morphology Metuods Cell and Molecular Biology Techniques (Lloyd RV ed) (Human Press) 10
  
  Pages: 165-180
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671469
[Journal Article] Drug-registance gene expression and progression of astrocytic tumors2001
- Author(s)
  Tanaka S, Kobayashi I, Oka H, Fujii K, Watanabe T, Nagashima T, Hori T
- Journal Title
  
  Brain Tumor Pathol 18-2
  
  Pages: 131-137
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671469

1. MATSUNO Akira (00242058)

# of Collaborated Projects: 8 results

# of Collaborated Products: 2 results
2. TANAKA Hideki (50276713)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
3. MATSUTANI Masao (90010454)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. 田中聡 (40179750)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. MURAKAMI Mineko (90229972)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TAKAKURA Kintomo (90109984)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. KATAYAMA Haruko (40307187)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. TAMURA Akira (80111532)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NAKAGOMI Tadayoshi (90198052)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 浅井昭雄 (50231858)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 平川誠 (30218771)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 中村博彦 (30189055)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. MOMOSE Toshimitsu (20219992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KAWAMOTO Shunsuke (00231275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KANEMITSU Hideaki (10129992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAKAYAMA Hitoshi (00147050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MURAYAMA Hiroyuki (50307188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HIRABAYASHI Shinichi (60173259)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YONEHARA Yoshiyuki (00251299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KAWANABE Takeshi (30303407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. FUJIMAKI Takamitsu (80251255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. TAKEKOSHI Susumu (70216878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. OSAMURA Yoshiyuki (10100992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 小出貢二 (10161853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 指田純 (70187152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 西原哲浩 (50260930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 設楽信行 (90111517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 喜多村一幸 (20195283)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 久保俊朗 (30195490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 源河茂 (30186580)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 西川亮 (90237678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 古屋一英 (40281373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 川合謙介 (70260924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 戸向則子 (30192214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 原徹男

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAGASHIMA Tadashi 長島 正

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Studies on the invasive potential of malignant gliomasPrincipal Investigator

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Study on the practical application of chemo-radiotherapy for malignant brain tumorPrincipal Investigator

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Studies on invasive properties of malignant gliomas and development of treatment modalities for these tumors.Principal Investigator

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悪性脳腫瘍の浸潤性増殖機構の解明とその克服に関する研究Principal Investigator

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悪性脳腫瘍の浸潤の評価とその克服に関する研究Principal Investigator

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脳腫瘍(グリオーマ)における遺伝子治療の試みPrincipal Investigator

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NAGASHIMA Tadashi 長島正