NAGASHIMA Tadashi 長島正

Researcher Number	70217991
Other IDs
External Links
Affiliation (based on the past Project Information) *help	1995 – 2005: 帝京大学, 医学部, 教授 1993 – 1994: 帝京大学, 医学部, 助教授 1990 – 1993: 東京大学, 医学部(病), 助手 1992: 東京大学, 医学部(病)脳神経外科, 助手 1991: 東京大学医学部(病), 脳神経外科, 助手 1990: 東京大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Cerebral neurosurgery Except Principal Investigator Cerebral neurosurgery / Cerebral neurosurgery / Plastic surgery
Keywords	Principal Investigator N-カドヘリン / invasion / グリオーマ / fibronectin / P53 / HGF / 蛍光標識 / ヌードラット / 悪性グリオーマ / 浸潤 … More / GEAP / MIB-1SI / fast blue / U87MG / U251MG / 腫瘍細胞浸潤 / トグリオーマ株細胞 / 蛍光染色 / ラミニン / ファイブロネクチン / MIB-1 / 弧発性腫瘍 / 多発性腫瘍 / GFAP / MIB-1 SI / MAP-1A mRNA / Antisense oligodeoxynucleotide / Low-dose / Cisplatin / Malignant brain tumor / 殺細胞効果 / NK活性 / CDDP / 化学療法 / 遺伝子治療 / アンチセンス / MAP-1A / MAP-1AmRNA / アンチセンスオリゴヌクレオチド / 少量連続投与 / ミスプラチン(CDDP) / 悪性脳腫瘍 / nude rat / in vivo / glioma / 免疫組織化学 / 浸潤能 / 湿潤能 / N-cadherin / cell-cell adhesion / malignant glioma / 細胞外マトリックス / 無血清培地 / locomotion / グリア系株化腫瘍細胞 / ラットグリオ-マ細胞株 / mーRNA / Nーカドヘリン / 回転培養 / 接着能 / 湿潤 / in situ hybridization / 細胞接着能 / C-Src / 細胞接着 / グリオーマ細胞 / 造腫瘍性 / BUdR-LI / 髓芽腫 / 膠芽腫 / P53遺伝子 … More Except Principal Investigator GFP / グリオーマ / phogrin / carboxypeptidase E / secretogranin 3 / chromogranin A / rab3B / syntaxin / SNAP-25 / 成長ホルモン / antisense oligonucleotide / apoptosis / アポトーシス / ニューロナビゲーター / secretory granule / pituitary cell / Growth hormone / 分泌顆粒 / 下垂体細胞 / brain damage / cranioplasty / rabbit / calvarial distraction / latent period / 骨延長 / 脳損傷 / 頭蓋形成術 / 家兎 / 仮骨延長 / antisense / secretion / Pituitary hormone / アンチセンス / Rab3B / 小胞輸送 / 分泌 / growth suppression / Microtubule-associated protein / gene therapy / glioma / 増殖抑制 / 微小管付随蛋白 / 遺伝子療法 / ceramide / sphingolipids / MRI / gene expression / remote neuronal damage / delayd neuronal death / ischemic neuronal death / 実質 / 遠隔部 / 脳温度 / c-myc / GAP-43 / アセチルコリン / 黒質 / 蛋白代謝 / マウス / ラット / 神経栄養因子 / ストレス蛋白質 / セラミド / スフィンゴミエリンサイクル / 遺伝子発現 / 遅発性神経細胞死 / 虚血性神経細胞死 / 前脳虚血 / 局所脳虚血 / Intraoperative Radiation Therapy / Radiation Therapy / Malignant Glioma / BUdR染色 / 脳腫瘍 / グリオブラストーマ / 予後規成因子 / 神経膠腫 / 術中照射 / 放射線治療 / 悪性グリオーマ / 養子免疫療法 / フローサイトメトリー / クリオーマ / 動注療法 / ウィルス発癌 / 発癌遺伝子 / 同調化化学放射線治療 / 3次元画像構成 / OKT3モノクロ-ナル抗体 / 3次元CT画像構成法 / サイトカイン / LAK療法 / GーCSF / 同調化化学放射線療法 / vErbB / 癌遺伝子 / Ley / Fi-67 / GFAP / 分化誘導 / ベスナリノン / 3次元CT / 生検 Less

Study on the molecular mechanism of secretory granule formation of pituitary hormone
- Principal Investigator
  
  MATSUNO Akira
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
Study on the molecular mechanism of the secretion of pituitary hormofie
- Principal Investigator
  
  MATSUNO Akira
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
Craniofacial bone an experimental study on craniofaicial disttaction osteogenesis
- Principal Investigator
  
  HIRABAYASHI Shinichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Teikyo University
Studies on the invasive potential of malignant gliomasPrincipal Investigator
- Principal Investigator
  
  NAGASHIMA Tadashi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
Study on the practical application of chemo-radiotherapy for malignant brain tumorPrincipal Investigator
- Principal Investigator
  
  NAGASHIMA Tadashi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
Studies on a novel gene therapy of glioma using antisense oligonucletide for microtubule-associated protein mRNA
- Principal Investigator
  
  MATSUNO Akira
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
Studies on invasive properties of malignant gliomas and development of treatment modalities for these tumors.Principal Investigator
- Principal Investigator
  
  NAGASHIMA Tadashi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
悪性脳腫瘍の浸潤性増殖機構の解明とその克服に関する研究Principal Investigator
- Principal Investigator
  
  長島正
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
悪性神経膠腫に対する経口化学療法剤の開発
- Principal Investigator
  
  田中聡
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
Study of mechanism of ischemic neuronal death.a molecular biological approach
- Principal Investigator
  
  TAMURA Akira
- Project Period (FY)
  1994 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo Univ.School of Med.
悪性脳腫瘍の浸潤の評価とその克服に関する研究Principal Investigator
- Principal Investigator
  
  長島正
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
脳外科手術における3次元的手術計画および支援システムの開発
- Principal Investigator
  
  小出貢二
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Teikyo University
脳腫瘍(グリオーマ)における遺伝子治療の試みPrincipal Investigator
- Principal Investigator
  
  長島正
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  The University of Tokyo
Basic and Clinical Study of Radiation Therapy for Malignant Gliomas
- Principal Investigator
  
  MATSUTANI Masao
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  University of Tokyo
Quantitative Study of Invasiveness of Malignant GliomasPrincipal Investigator
- Principal Investigator
  
  NAGASHIMA Tadashi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  University of Tokyo
悪性神経膠腫のウィルス発癌と総合的治療法に関する総合的研究
- Principal Investigator
  
  TAKAKURA Kintomo
- Project Period (FY)
  1987 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  The University of Tokyo

All 2002 2001

All Journal Article

[Journal Article] Growth factor of gliomas2002
- Author(s)
  Nagashima T
- Journal Title
  
  Neurosurgery Advanced Practice (Takakura K, et al ed) (Medical View) 5
  
  Pages: 164-167
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671469
[Journal Article] 神経膠腫の成長因子2002
- Author(s)
  長島正
- Journal Title
  
  脳神経外科Advanced Practice 5
  
  Pages: 164-167
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671469
[Journal Article] Intracellular localiztion of secreted proteins and their mRNAs, detected by ultrastractural in situ hybridization method2002
- Author(s)
  Matsuno A, Nagashima T, Takekoshi S, Utunomiya H, Oosugi Y, Osamura Y
- Journal Title
  
  J of Japan Electromicroscopic Sociaty 37
  
  Pages: 85-88
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671469
[Journal Article] 腫瘍マーカー2001
- Author(s)
  長島正
- Journal Title
  
  Clinical : Neuroscience 19
  
  Pages: 307-309
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671469
[Journal Article] Tumor marker2001
- Author(s)
  Nagashima T
- Journal Title
  
  Clinical Neuroscience 19-3
  
  Pages: 307-309
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671469
[Journal Article] Confocal Laser Scaning Microscopy2001
- Author(s)
  Matsuno A, Itoh J, Nagashima T, Osamura Y, Watanabe K
- Journal Title
  
  Morphology Metuods Cell and Molecular Biology Techniques (Lloyd RV ed) (Human Press) 10
  
  Pages: 165-180
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671469
[Journal Article] Drug-registance gene expression and progression of astrocytic tumors2001
- Author(s)
  Tanaka S, Kobayashi I, Oka H, Fujii K, Watanabe T, Nagashima T, Hori T
- Journal Title
  
  Brain Tumor Pathol 18-2
  
  Pages: 131-137
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671469

1. MATSUNO Akira (00242058)

# of Collaborated Projects: 8 results

# of Collaborated Products: 2 results
2. TANAKA Hideki (50276713)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
3. MATSUTANI Masao (90010454)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. 田中聡 (40179750)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. MURAKAMI Mineko (90229972)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TAKAKURA Kintomo (90109984)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. KATAYAMA Haruko (40307187)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. TAMURA Akira (80111532)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NAKAGOMI Tadayoshi (90198052)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 浅井昭雄 (50231858)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 平川誠 (30218771)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 中村博彦 (30189055)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. MOMOSE Toshimitsu (20219992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KAWAMOTO Shunsuke (00231275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KANEMITSU Hideaki (10129992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAKAYAMA Hitoshi (00147050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MURAYAMA Hiroyuki (50307188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HIRABAYASHI Shinichi (60173259)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YONEHARA Yoshiyuki (00251299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KAWANABE Takeshi (30303407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. FUJIMAKI Takamitsu (80251255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. TAKEKOSHI Susumu (70216878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. OSAMURA Yoshiyuki (10100992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 小出貢二 (10161853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 指田純 (70187152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 西原哲浩 (50260930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 設楽信行 (90111517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 喜多村一幸 (20195283)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 久保俊朗 (30195490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 源河茂 (30186580)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 西川亮 (90237678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 古屋一英 (40281373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 川合謙介 (70260924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 戸向則子 (30192214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 原徹男

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAGASHIMA Tadashi 長島 正

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the invasive potential of malignant gliomasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the practical application of chemo-radiotherapy for malignant brain tumorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on invasive properties of malignant gliomas and development of treatment modalities for these tumors.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

悪性脳腫瘍の浸潤性増殖機構の解明とその克服に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

悪性脳腫瘍の浸潤の評価とその克服に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脳腫瘍(グリオーマ)における遺伝子治療の試みPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

NAGASHIMA Tadashi 長島正