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HIGASHIHARA Eiji  東原 英二

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… Alternative Names

東原 英二  ヒガシハラ エイジ

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Researcher Number 00092312
Other IDs
Affiliation (Current) 2025: 杏林大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help 2018: 杏林大学, 医学部, 特任教授
2017: 杏林大学, 医学部, 教授
2016: 杏林大学, 医学部, 特任教授
2012 – 2014: 杏林大学, 医学部, 教授
2003 – 2007: 杏林大学, 医学部, 教授 … More
1997 – 1999: 杏林大学, 医学部, 教授
1994 – 1995: 杏林大学, 医学部, 教授
1991 – 1993: 東京大学, 医学部(病), 助教授
1992: 東京大学医学部(病), 泌尿器科学, 助教授
1990: 東京大学, 医学部, 助教授
1990: 東京大学, 医学部・附属病院, 助教授
1989: 東京大学, 医学部(病)・泌尿器科, 助教授
1988 – 1989: 東京大学, 医学部(病), 助教授
1986: 東大, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
Urology
Except Principal Investigator
Urology / Urology / 応用薬理学・医療系薬学
Keywords
Principal Investigator
quantitative RT-PCR / autocrine factor / c-met / polymerase chain reaction / prostate specific membrane antigen / prostate specific antigen / prostate cancer / PSM / PSA / 前立腺癌 … More / PCR / RENAL CELL CARCINOMA / HEPATOCYTE GROWTH FACTOR / インターフェロンα / メッセンジャーRNA / 肝細胞増殖因子 / 腎癌 / RT-PCR / HGF / 腎細胞癌 / 肝細胞増殖因子(HGF) / Adrenalectomy / Nephrectomy / Laparoscopy / 副腎摘除 / 腎摘除 / 腹腔鏡 / ○スロンボキサン / ○低蛋白食 / ○尿路感染症 / ○腎硬化症 … More
Except Principal Investigator
多発性嚢胞腎 / ERK / MEK / Elk-1 / 膀胱癌 / PC-12 / カテコールアミン / カテコ-ルアミン / 褐色細胞腫 / ベンゾイソフラノン化合物 / ベンゾイソフラノン誘導体 / PCKラット / マクロファージ / 血管保護 / CD31 / HIF-1 / NG2 / ペリサイト / PCKラット / HIF / Gag遺伝子 / 内在性レトロウイルス / pericyte / polycystic kidney / MEK inhivitor / MAPK / baldder cancer / S MEK 阻害薬 / MAPキナーゼ / FANCF gene / hypermethylation / bladder cancer / FANCF遺伝子 / メチル化 / renal cell carcinoma / The addition of the histone deacety / adenovirus / 遺伝子治療 / histone deacetylase inhibitors / ヒストン脱アセチル化酵素 / 腎癌 / レストン脱アセチル化酵素 / アデノウイルス / differential display method / FISH mapping / cloning of kidney cyst-related genes / human genome BAC library / PKDI mutation / DNA diagnosis / polycystic kidney disease / ヒトゲノムBACライブラリースクリーニング / デイファレンシャルデイスプレイ法 / デファレンシャルデイスプレイ法 / FISHマッピング / 腎嚢胞形成関連遺伝子クローニング / ヒトゲノムBACライブラリー / PKD1変異解析 / DNA診断 / VITAMIN D_3 RECEPTOR RNA / PTHmRNA. / BONE MINERAL DENSITY. / ACID-BASE BALANCE. / PRIMARY HIPERPARATHYROIDISM. / 酸塩基平衡 / カルシウム代謝 / 原発性副甲状腺機能亢進症 / 電解質酸塩基平衡 / ビタミンD_3受容体RNA / PTHmRNA / 骨密度 / 電解質酸塩基手術 / 副甲状腺機能亢進症 / nifedipine / prazosion / catecholamine / pheochromocytoma / rat / PC12細胞 / カルシウム拮抗剤 / アルファ庶断薬 / 高血圧性変化 / ラット褐色細胞腫 / ニフェジピン / プラゾシン / カテコラミン / ラット / 尿管 / 波長可変レーザー砕石器 / 内視鏡画像処理 / 組織障害作用 / リン酸カルシウム / シュウ酸カルシウム / パルスレーザー光 / 尿路結石 / レーザー砕石 / 波長 / シスチン結石 / リン酸カルシウム結石 / シュウ酸カルシウム結石 / 波長可変 / 軟性尿管鏡 / 歪ゲ-ジ / 衝撃波 / 反射率 / 燐酸カルシウム結石 / 蓚酸カルシウム結石 / 波長480nm / パルス波色素レ-ザ- / Ca Channel Blocker / ATP / 形態計測 / ニコチン / DNAメチル化 / 細胞外マトリクス / ラットPCK / 細胞マトリックス / stone belt / 有機アニオントランスポーター / 低カリウム血症 / 突然死 / 周期性四肢麻痺 / 腎遠位尿細管性酸血症 / 地域多発性尿路結石 Less
  • Research Projects

    (15 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (35 People)
  •  Ameriolation of progression of polycystic kidney disease by stabilization of renal vessel disorders and exploration of endogenous retrovirus responses in macrophages

    • Principal Investigator
      Ishibashi Michio
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Nara Medical University
  •  Basic studies of therapeutic modality for polycystic kidney disease explored by epigenetic modification of cellular matrix-adhesion proteins

    • Principal Investigator
      ISHIBASHI MIchio
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Nara Medical University
  •  ANALYSIS OF MAP-KINASE IN THE BLADDER CANCER AND TARGETED MOLECULAR STRATEGIES BASED ON THE BLOCKADE OF THE MAP-KINASE PATHWAYS

    • Principal Investigator
      SHISHIDO Toshishide
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kyorin University
  •  Methylation of DNA as a prognostic marker for bladder cancer

    • Principal Investigator
      OKEGAWA Takatsugu
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kyorin University
  •  ENHANCED TRANSGENE EXPRESSION IN RENAL CELL CANCER GENE THERAPY WITH HISTONE DEACETYLASE INHIBITOR

    • Principal Investigator
      OKEGAWA Takatsugu
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kyorin University
  •  Development of DNA diagnosis method of polycystic kidney disease and cloning of genes related to the formation of kidney cysts

    • Principal Investigator
      SHIMIZU Yoshiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      KYORIN UNIVERSITY
  •  東アジアに多発する尿路結石の実態と素因

    • Principal Investigator
      遠藤 仁
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kyorin University
  •  Molecular Staging of Prostatic Cancer : Comparison of the Nasted Reverse Transcription Polymerase Chain Reaction Assays of Prostate Specific Antigen versus Prostate Specific Membrane Antigen as primers.Principal Investigator

    • Principal Investigator
      HIGASHIHARA Eiji
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kyorin University School of Medicine
  •  PTHmRNA and vitamin D_3 receptor RNA in primary hyperparathyroidism.

    • Principal Investigator
      NUTAHARA Kikuo
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      KYORIN UNIVERSITY
  •  GENE EXPRESSION OF HEPATOCYTE GROWTH FACTOR (HGF) IN RENAL CELL CARCINOMAPrincipal Investigator

    • Principal Investigator
      HIGASHIHARA Eiji
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  The effect of a calcium antagonist and ATP on blood pressure in a rat model of pheochromocytoma

    • Principal Investigator
      HOMMA Yukio, 阿曽 佳郎
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Urology
    • Research Institution
      University of Tokyo
  •  Development of endoscopic retroperitoneal surgery.Principal Investigator

    • Principal Investigator
      HIGASHIHARA Eiji
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      University of Tokyo
  •  副腎髄質疾患における各種薬剤の降圧作用に関する研究

    • Principal Investigator
      阿曽 佳郎
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      The University of Tokyo
  •  内視鏡的上部尿路結石砕石用レ-ザ-装置の開発

    • Principal Investigator
      阿曽 佳男 (阿曽 佳郎)
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      The University of Tokyo
  •  腎不全の進行に対する食事及び薬剤治療の実験的研究Principal Investigator

    • Principal Investigator
      東原 英二
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      The University of Tokyo

All 2019 2018 2004

All Journal Article Presentation

  • [Journal Article] Value of reverse transcription polymerase chain assay in peripheral blood of patients with urothelial cancer.2004

    • Author(s)
      Okegawa T, Kinjo M, Nutahara K, Higashihara E.
    • Journal Title

      J Urol. 171(4)

      Pages: 1461-1466

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591714
  • [Presentation] NG2活性化による腎髄質ペリサイト機能温存とラットPCK 多発性嚢胞腎モデルにみられる糸球体病変の軽減2019

    • Author(s)
      熊本海生航、釘田雅則、吉村文、藤本清秀、千原良友、小島直人、東原英二、長尾静子、石橋道男
    • Organizer
      第62回日本腎臓学会学術総会、2019年6月21日 名古屋
    • Data Source
      KAKENHI-PROJECT-16K11058
  • [Presentation] 多発性嚢胞腎ラットへの低分子化合物NK0070投与によるNG2 pericyte マーカーの温存と腎病変2018

    • Author(s)
      石橋道男、釘田雅則、熊本海生航、吉村 文、 藤本清秀、東原英二、長尾静子
    • Organizer
      第48回日本腎臓学会東部学術大会、平成30年(2018)10月20日~21日、東京
    • Data Source
      KAKENHI-PROJECT-16K11058
  • 1.  NUTAHARA Kikuo (00143470)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 2.  簑和田 滋 (00126179)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  OKEGAWA Takatsugu (70306679)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 4.  阿曽 佳郎 (00009961)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  HOMMA Yukio (40165626)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  TAKEUCHI Takumi (90167487)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  ISHIBASHI MIchio (40107032)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 8.  NAGAO Shizuko (20183527)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 9.  OSHI Masaya (60143468)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  CHIHARA Yoshitomo (40405395)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KOJIMA Naoto (90420413)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TANAKA Yoshinori (50236650)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  HORIE Shigeo (40190243)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MORIYAMA Nobuo (80143501)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MURATA Akihiro (80291657)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  SHIMIZU Yoshiko (50255410)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  YAMAKI Akiko (40296546)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SHISHIDO Toshishide (40307327)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  遠藤 仁 (20101115)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  五十嵐 隆 (70151256)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  河合 祥雄 (40138194)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  千葉 百子 (80095819)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  稲葉 裕 (30010094)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  富永 登志 (70107605)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  佐山 孝 (90187287)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  朝蔭 裕之 (20191851)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  中村 昌平 (40107636)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  上條 利幸 (50233937)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  米田 龍生 (50286415)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  渡辺 和吉 (60407054)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  TERADA Masayuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  TAMURA Takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  福庭 雅洋
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  西古 靖
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  森田 良治
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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