SHIRAKURA Ryota 白倉良太

… Alternative Names

白倉良太シラクラリヨウタ

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Researcher Number	00116047
Other IDs
Affiliation (Current)	2025: 大阪大学, その他部局等, 名誉教授
Affiliation (based on the past Project Information) *help	1999 – 2005: Graduate School of Medicine, Osaka University Professor, 医学系研究科, 教授 1993 – 1998: 大阪大学, 医学部, 教授 1990 – 1992: Osaka Univ. First Dept. of Surg Assoc. Prof., 医学部, 助教授 1989 – 1990: 大阪大学, 医学部, 助手 1986: 阪大, 医学部, 助手
Review Section/Research Field	Principal Investigator Thoracic surgery / Thoracic surgery / General surgery Except Principal Investigator Thoracic surgery / Thoracic surgery / General surgery / General surgery
Keywords	Principal Investigator HLA-E / HLA-G1 / 慢性拒絶反応 / 免疫寛容 / 異種移植 / NK細胞 / delation mutant / FasL / HLA-G / HLA-Ib … More / NK cell / 戻し心移植法 / CD59 / MCP (CD46) / DAF (CD55) / 心移植 / マウス / ブタ血管内皮 / NK cell-dependent cell lysis / CRP / 補体制卸因子 / NK細胞依存性細胞障害 / HLA-lb / NK細胞依存性細胞傷害 / delationmutant / 補体制御因子 / hlycosyltransferase / pig eridothelial cell / β2 microglobulin / β_2microglobulin / 糖転位酵素 / 糖転移酵素 / ブタ血管内皮細胞 / Quantitative RT-PCR / Heterotopic heart transplantation / Rat / Chronic rejection / 定量的RT-PCR法 / 定量RT-PCR法 / ラット異所性心移植 / Mice / T-cells / Transplantation tolerance / T細胞 / PCR / Tranplant vasculopathy / retransplantation technique / rat heart graft / In Situ PCR法 / SRY遺伝子 / ラット / PCR法 / ラット心移植 / GUIDELINE / PIG / BABOON / XENOGRAFTS / 異種心移植 / ガイドライン / ブタ / ヒヒ / Transgenic / Complement / Xenograft / CD4+T cell / nonMHC / Transfection / C9D / transgenic / transfection / CD59(MACIF) / MCP(CD46) / DAF(CD55) / トランスジェニック / 補体 / Cloning / Interleukin 2 / inducer T cell / Suppressor / Cytotoxic T cell precursor frequency / Limiting dilution assay / Graft infiltrating cells / Heart transplantation / Acute rejection / インタ-ロイキン2 / 細胞障害性T前駆細胞頻度 / インタ-ロイキニン / 心移殖 / クロ-ニング / インタ-ワイキン2 / サプレッサ-・インデュ-サ-T細胞 / 細胞傷害性T前駆細胞頻度 / 限界稀釈法 / グラフト浸潤細胞 / 急性拒絶反応 / サイクロスポリン / 拒絶反応の非侵襲的診断 / 免疫抑制ラット異所性心移植 / 尿中排泄量 / スロンボキサン【B_2】 / 心拒絶反応 / PD-1リガンド / ケモカイン / 組み替えアデノウイルス / ラット大動脈移植 / キメリズム / トレランスアッセイ / 拒絶反応 / Green Fluorescence protein / 脾細胞静脈内投与 / アロ免疫応答 / β1,4N-acetylglucosaminy ltransferase III / α1,2Fucosyl transferase / α2,3Sialyl transferase / α2,6Sialy transferase / N-グリコリル型シアル酸 / Hanganutziu-DDeicher 抗原 / α1,3Galactosyl epitope / 糖鎖構造 … More Except Principal Investigator DAF / 遺伝子導入 / 異種移植 / 慢性拒絶反応 / FK506 / CAM / ブタ / 補体制御因子 / 心移植 / 心臓移植 / 超急性拒絶反応 / 異種心臓移植 / Chronic rejection / 戻し心移植法 / ラット異所性心移植 / HEART TRANSPLANTATION / pig islet / mRNA differential display / RFDD / quantitative RT-PCR / Retransplantation / heterotopic rat heart transplantation / CXCR3 / 定量RT-PCR法 / Factor I / HSV-gC1 / C1-INH / B細胞 / Differential display / Pig / PERCUTANEOUS CARDIOPULOMONARY BYPASS / NON-HEART-BETING DONORS / 腎移植 / 肺移植 / トランスジェニックマウス / GnT-III / ブタ血管内皮 / HSP 70 / HVJ-liposome / Nicorandil / AP4A / ヒヒ / 移植心冠動脈硬化症 / 遺伝子治療 / Neutrophil / Migration / Adhesion / Endothelial cell / Myocyte / Cytokine / Reperfusion / Hyperacute rejection / 異種心移植 / CD59 / CD55 / FUT175 / heart transplantation / 心保存 / ラット / Cyclosporine / 免疫寛容 / 補体抑制剤 / discordant系 / 経皮的体外循環装置 / 無呼吸心停止ドナー / co-stimulatory molecules / transplantation / immunological tolerance / T細胞 / PD1 / PD-1リガンド / 筋芽細胞 / 組み替えアデノウイルス / 副刺激分子 / 移植 / α-1,3GT / α-Gal antigen / glycoantigen / Complement deposit / CRP / ブタislet / MCP / 補体抑制因子 / α1,3GT活性 / α-Gal抗原 / 糖鎖抗原 / 膜残存補体 / factor I / Immunoabsorption / Hyper Acute Rejection / Transgenic Pig / Rhesus Monkey / Xenografts / N-acetylglucosamiltransferase / decay acclerating factor / 臓器灌流 / decay accelerating factor / 遺伝導入 / 抗体吸着 / 遺伝子導入ブタ / アカゲザル / Antibody / B cells / 免疫グロブリン / MHCクラスII抗原 / CD11b / 抗体 / mRNA Differential display / Chemokine / aortic transplantation / 接着分子 / ラット異所性大動脈移植移植 / ケモカイン / ラット異所性大動脈移植 / CHO cell / pig endothelial cell / Complement regulatory protein / 細胞傷害性試験 / ブタ血管内皮細胞 / CHO細胞 / heterotopic heart transplantation / Rat / イムノグロブリンkappa鎖 / Anti-pig antibody / Babboon / Xenotransplantation / 異所性移植モデル / 前感作抗体 / Discordant異種心臓移植 / apoptosis / 免疫抑制療法 / 抗体除去 / 霊長類 / 抗ブタ抗体 / MULTIORGAN PROCUREMENT / KIDNEY TRANSPLANTATION / LUNG TRANSPLANTATION / BEAGLE / 心、肺、腎移植 / 多臓器移植 / 無呼吸下停止心ドナー / 経皮的体外循環 / ビーグル犬 / 多臓器提供システム / 無呼吸F停止心ドナー / BCL-2 / GRAFT CORNARY ATHEROSCRELOSIS / HJV-LIPOSOME METHOD / RAT / HAMSTER / GENE TRANSFECTION / 血管内皮細胞 / アポトーシス / HVJリポゾーム法 / 移植後冠動脈硬化症 / Bcl-2 / HVJ リポゾーム法 / ハムスター / 遺伝子導入法 / alpha2-3 ST / alpha1-3galactosyltransferase / alpha2-6sialyltransferase / tansfect / α2-3ST / α1-3galactosyltransferase / α2-6sialyltransferase / 糖鎖 / Non-Depolarizing Cardioplegia / Ischemia-Reperfusion Injury / Myocardial Protection / 虚血再潅流 / HSP70 / 非脱分極性心筋保護液 / 虚血再潅流障害 / 心筋保護 / Gene Transfection / Cryopreseavation / 凍結保存法 / 凍結保存 / ANTI-PIG RBC ANTIBODIES / HYPER ACUTE REJECTION / PIG / BABOON / XENOGRAFTS / ガイドライン / 抗ブタ赤血球抗体 / 抗赤血球抗体 / 頸部異所性移植 / retransplantation / chronic rejection / graft coronary arteriosclerosis / 冠動脈硬化 / 戻し移植 / Stent / Vein graft / Vein graft disease / HVJ liposome method / Gene transfection / 再狭窄 / 静脈グラフト病変 / アンチセンス / 平滑筋細胞 / ステント / 静脈グラフト / Vein Graft Disease / HVJリボゾーム法 / DNA engineering / heat shock protein / cardiac preservation / ischemia-reperfusion / myocardial protection / gene transfection / 心筋虚血再灌流障害 / Heat shock Protein / DNA組みかえ / 心筋虚血耐性 / HVJ-liposome法 / ストレス蛋白 / 心保存法 / DNA組換え / 熱ショックプロテイン / 虚血再灌流障害 / 心筋保護法 / Free Radical / Adhesir / Cytolsine / neutrophil / Free radical / Nevtrophil / catecholamine / myocardial Injury / Brain Death / beta-adrenergic Receptor / βーアドレナリンレセプタ- / カテコ-ルアミン / 心筋障害 / 脳死 / βアドレナリン・レセプタ- / CD4 T cell / Natural antibody / Discordant cardiac xenograft / Anti-complement drug / 豚、雑種成犬 / モルモット・ラット / nafamstat mesilate(FUTー175) / Bridge use / 抗補体レセプタ-抗体 / MACIF / 補体 / CD4陽性T細胞 / 抗補体レセプター抗体 / 細胞性免疫応答 / 異種抗体 / K76 / 抗CD4モノクローナル抗体 / 抗血管内皮抗体 / 自然抗体 / 抗補体剤 / impedance / pulsatile flow / heart preservation / 低温保存 / 潅流保存 / インピ-ダンス / 拍動流 / graft Coronary Artery / Chronic Cardiac Rejection / 冠状動脈狭窄 / 血管内皮細胞損傷 / 冠動脈 / 同種移植 / 心筋梗塞 / 再生医療 / 幹細胞 / スパ-ガリン / サプレッサ-T細胞 / IL2産生 / 細胞傷害性T細胞 / 限界希釈法 / 骨髄細胞 / モルモット、ラット / nafamostat mesilate(175-FUT) / コブラ毒(cobra venom) / Bridge Use Less

造血系幹細胞株の樹立と再生医療を目指したアロ免疫寛容誘導に関する研究
- Principal Investigator
  
  榊田悟
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
ESTABLISHMENT OF MULTIORGAN PROCUREMENT SYSTEM FROM NO-HEART-BEATING DONOR USING PERCUTANEOUS CARDIOPULMONARY BYPASS
- Principal Investigator
  
  FUKUSHIMA Norihide
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
The suppression of the delayed-type xenograft rejection
- Principal Investigator
  
  MIYAGAWA Shuji
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Downregulation of the NK cell activity on xenograftPrincipal Investigator
- Principal Investigator
  
  SHIRAKURA Ryota
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
A study for the induction of transplantation tolerance using adenovirus expressing PD-1 ligands and application to myoblast transplantation into infarcted hearts.
- Principal Investigator
  
  SAKAKIDA Satoru
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  OSAKA UNIVERSITY
局所遺伝子導入による移植後動脈硬化症に対する特異的治療法開発Principal Investigator
- Principal Investigator
  
  白倉良太
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
ESTABLISHMENT OF IMMUNOSUPPRRESIVE METHOD FOR CLINICAL DISCORDANT XENOGENEIC CARDIAC TRANSPLANTATION
- Principal Investigator
  
  FUKUSHIMA Norihide
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
アロ抗原の存続とAICDの有無による移植免疫寛容の臨床診断法確立への予備的研究Principal Investigator
- Principal Investigator
  
  白倉良太
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
An experimental study to detect unknown or unexpected genes expressed in the developmental phase of transplant vasculopathy.
- Principal Investigator
  
  SAKAKIDA Satoru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
Green miceを用いた移植免疫寛容誘導に関わる新規遺伝子クローニングの試みPrincipal Investigator
- Principal Investigator
  
  白倉良太
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
Prevention of acute vascular rejection in xenograft
- Principal Investigator
  
  MIYAGAWA Shuji
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
The strategy for inhibiting NK cell activity by gene technologyPrincipal Investigator
- Principal Investigator
  
  SHIRAKURA Ryota
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
An experimental study developing new therapeutic strategy for cardiac allograft vasculopathy : selective chemokine/receptor systems as molecular targets
- Principal Investigator
  
  SAKAKIDA Satoru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
異種移植における新糖鎖抗原の探究Principal Investigator
- Principal Investigator
  
  白倉良太
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
ESTABLISHMENT OF IMMUNOSUPPRESIVE METHOD FOR CLINICAL DISCORDANT XENOGENEIC CARDIAC TRANSPLANTATION
- Principal Investigator
  
  OHTAKE Shigeaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
A study searching for new genes in chronic cardiac rejection using PCR-based differential display.
- Principal Investigator
  
  SAKAKIDA Satoru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
NK細胞の標的糖鎖構造の探究Principal Investigator
- Principal Investigator
  
  白倉良太
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
A study for the in vivo mechanism of transplantation tolerance using GFP transgenic micePrincipal Investigator
- Principal Investigator
  
  SHIRAKURA Ryota
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
A study of molecular diagnosis and treatment for chronic cardiac allograft rejection.Principal Investigator
- Principal Investigator
  
  SHIRAKURA Ryota
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
ESTABLISHMENT OF NEW IMMUNOSUPPRESSIVE STRATEGY USING GENE TRANSFECTION TECHNIQUE
- Principal Investigator
  
  FUKUSHIMA Norihide
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  OSAKA UNIVERSITY
ESTABLISHMENT OF MULTIORGAN PROCUREMENT SYSTEM FROM NO-HEART-BEATING DONOR USING PERCUTANEOUS CARDIOPULMONARY BYPASS
- Principal Investigator
  
  FUKUSHIMA Norihide
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  OSAKA UNIVERSITY
The study elucidating the molecular mechanisms underlying transplant vasculopathyPrincipal Investigator
- Principal Investigator
  
  SHIRAKURA Ryota
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
The remodeling of glycoantigen for clinical xenotransplantation.
- Principal Investigator
  
  MIYAGAWA Syuuji
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
ESTABLISHMENT OF IMMUNOSUPPRRESIVE METHOD FOR CLINICAL DISCORDANT XENOGENEIC CARDIAC TRANSPLANTATION
- Principal Investigator
  
  FUKUSHIMA Norihide
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  OSAKA UNIVERSITY
Deveropment of Cryopreseaved Allograft with Gene Introduction
- Principal Investigator
  
  KADOBA Keisi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
Study of newly developed cardioplegia for long term myocardial preservation
- Principal Investigator
  
  SAWA Yoshiki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
A novel myocardial protection with in vivo gene transfection
- Principal Investigator
  
  MATSUDA Hikaru
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
ESTABLISHMENT OF IMMUNOSUPPRRESIVE METHOD FOR CLINICAL XENOTRANSPLANTATIONPrincipal Investigator
- Principal Investigator
  
  SHIRAKURA Ryota
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  OSAKA UNIVERSITY
The Research for Regulation of Vascular Stenosis by Antisense Delivery System
- Principal Investigator
  
  SAWA Yoshiki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
Analysis for the mechanism of graft coronary arteriosclerosis
- Principal Investigator
  
  TANIGUCHI Kazuhiro
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
New myocardial motection with cytokine network.
- Principal Investigator
  
  NAKANO Susumu
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
The development of xenograftPrincipal Investigator
- Principal Investigator
  
  SHIRAKURA Ryota
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
骨髄移植及び短期免疫抑制剤併用によるラット心移植の寛容誘導に関する研究
- Principal Investigator
  
  中田精三
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Experimental study for the clinical application of discordant cardiac xenograft.
- Principal Investigator
  
  NAKANO Susumu
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
Myocardial beta-adrenoceptor Function after brain death
- Principal Investigator
  
  TANIGUCHI Kazuhiro
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
異種移植のBridge Useの可能性についての基礎的研究
- Principal Investigator
  
  川島康生
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
The Clonal Analysis of Effector Mechanism in Graft RejectionPrincipal Investigator
- Principal Investigator
  
  SHIRAKURA Ryota
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Osaka
The mechanism of chronic cardiac rejection in connection with the endothelial cell injury
- Principal Investigator
  
  ITO Toshinori, 川口章
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
Development of a pulsatile perfusion apparatus for heart preservation with myocardial impedance monitor
- Principal Investigator
  
  KANEKO Mitsunori, 川島康生
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University
尿中プロスタノイド代謝物の定量による拒絶反応の早期診断に関する研究Principal Investigator
- Principal Investigator
  
  白倉良太
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Osaka University

All 2005 2004 2003 2002 Other

All Journal Article

[Journal Article] Adult islet grafts from transgenic pigs with N-acetylglucosaminyltransferase-III (GnT-III) indicate a prolonged survival in the cynomolgus monkey.2005
- Author(s)
  Hiroshi Komoda, Shuji Miyagawa, Takeshi Omori, Yoichi Takahagi, Hiroshi Murakami, Tamotsu Shigehisa, Toshinori Ito, Hikaru Matsuda, Ryota Shirakura
- Journal Title
  
  Xenotransplantation 12(3)
  
  Pages: 209-216
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390377
[Journal Article] Production of a1,3-Galactosyltransferase Gene Knockout Pigs Expressing Both Human Decay-Accelerating Factor and N-Acetylglucosaminyltransferase III.2005
- Author(s)
  Yoichi Takahagi, Tatsuya Fujimura, Shuji Miyagawa, Hiroshi Nagashima, Tamotsu Shigehisa, Ryota Shirakura, Hiroshi Murakami
- Journal Title
  
  Mol Reprod Dev. 71(3)
  
  Pages: 331-338
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390414
[Journal Article] Production of a1,3-Galactosyltransferase Gene Knockout Pigs Expressing Both Human Decay-Accelerating Factor and N-Acetylglucosaminyltransferase III.2005
- Author(s)
  Yoichi Takahagi, Tatsuya Fujimura, Shuji Miyagawa, Hiroshi Nagashima, Tamotsu Shigehisa, Ryota Shirakura, Hiroshi Murakami
- Journal Title
  
  Mol Reprod Dev. 71(3)
  
  Pages: 331-338
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390377
[Journal Article] Adult islet grafts from transgenic pigs with N-acetylglucosaminyltransferase-III (GnT-III) indicate a prolonged survival in the cynomolgus monkey.2005
- Author(s)
  Hiroshi Komoda, Shuji Miyagawa, Takeshi Omori, Yoichi Takahagi, Hiroshi Murakami, Tamotsu Shigehisa, Toshinori Ito, Hikaru Matsuda, Ryota Shirakura
- Journal Title
  
  Xenotransplantation 12(3)
  
  Pages: 209-216
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390414
[Journal Article] Cloning the transgenic pigs expressing human decay accelerating factor and N-acetylglucosaminyltransferase III.2004
- Author(s)
  Tatsuya Fujimura, Mayuko Kurome, Hiroshi Murakami, Yoichi Takahagi, Katsuyoshi Matsunami, Shinichi Shimanuki, Kohei Suzuki, Shuji Miyagawa, Ryota Shirakura, Tamotsu Shigehisa, Hiroshi Nagashima
- Journal Title
  
  Cloning and Stem Cells 6(3)
  
  Pages: 294-301
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390414
[Journal Article] Delta-short consensus repeat 4-decay accelerate factor (DAF:CD55) inhibits complement-mediated cytolysis but not NK cell-mediated cytolysis2004
- Author(s)
  Shuji Miyagawa, Tomoko Kubo, Katsuyoshi Matsunami, Tamiko Kusama, Hiroshi Nozaki, Toshiyuki Moritan, Curie Ahn, Jae Young Kim, Daisuke Fukuta, Ryota Shirakura
- Journal Title
  
  J.Immunol. 173(6)
  
  Pages: 3945-3952
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390377
[Journal Article] Skin graft of double transgenic pigs of N-acetylglucosaminyltransferase III (GnT-III) and DAF (CD55) genes survived in cynomolgus monkey for 31 days.2004
- Author(s)
  Tatsuya Fujita, Shuji Miyagawa, Kyouri Ezoe, Tamotsu Saito, Noriyuki Sato, Yoichi Takahagi, Hiroshi Murakami, Katsuyoshi Matsunami, Ryota Shirakura, Naoyuki Taniguchi
- Journal Title
  
  Transplant Immunology 13(4)
  
  Pages: 259-264
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390414
[Journal Article] Skin graft of double transgenic pigs of N-acetylglucosaminyltransferase III (GnT-III) and DAF (CD55) genes survived in cynomolgus monkey for 31 days.2004
- Author(s)
  Tatsuya Fujita, Shuji Miyagawa, Kyouri Ezoe, Tamotsu Saito, Noriyuki Sato, Yoichi Takahagi, Hiroshi Murakami, Katsuyoshi Matsunami, Ryota Shirakura, Naoyuki Taniguchi
- Journal Title
  
  Transplant Immunology 13(4)
  
  Pages: 259-264
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390377
[Journal Article] Delta-short consensus repeat 4-decay accelerate factor (DAF:CD55) inhibits complement-mediated cytolysis but not NK cell-mediated cytolysis2004
- Author(s)
  Shuji Miyagawa, Tomoko Kubo, Katsuyoshi Matsunami, Tamiko Kusama, Hiroshi Nozaki, Toshiyuki Moritan, Curie Ahn, Jae Young Kim, Daisuke Fukuta, Ryota Shirakura
- Journal Title
  
  J.Immunol. 173(6)
  
  Pages: 3945-3952
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390414
[Journal Article] A study of adult pig islets profiles.2004
- Author(s)
  Hiroshi Komoda, Shuji Miyagawa, Tomoko Kubo, Etsuko Kitano, Hajime Kitamura, Kenji Omori, Toshinori Ito, Hikaru Matsuda, Ryota Shirakura
- Journal Title
  
  Xenotransplantation 11
  
  Pages: 237-246
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390377
[Journal Article] The heavy chain is not required for the serine protease function of the membrane bound form of factor I on a xeno-surface.2004
- Author(s)
  Daisuke Fukuta, Shuji Miyagawa, Tomoko Kubo, Tamiko Kusama, Akio Shirasu, Hiroyuki Hattori, Ryota Shirakura
- Journal Title
  
  Transplant Immunol 12
  
  Pages: 109-114
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390377
[Journal Article] Cloning the transgenic pigs expressing human decay accelerating factor and N-acetylglucosaminyltransferase III.2004
- Author(s)
  Tatsuya Fujimura, Mayuko Kurome, Hiroshi Murakami, Yoichi Takahagi, Katsuyoshi Matsunami, Shinichi Shimanuki, Kohei Suzuki, Shuji Miyagawa, Ryota Shirakura, Tamotsu Shigehisa, Hiroshi Nagashima
- Journal Title
  
  Cloning and Stem Cells 6(3)
  
  Pages: 294-301
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390377
[Journal Article] Effect of various forms DAF(CD55) and C1 esterase inhibitor (C1-INH)2003
- Author(s)
  D Fukuta, S Miyagawa, M Yamada, K Matsunami, T Kurihara, A Shirasu, H Hattori, R Shirakura
- Journal Title
  
  Transtrant Proc 35(1)
  
  Pages: 519-520
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390377
[Journal Article] Downregulation of NK cell-mediated swine endothelial cell lysis by (CD55)2003
- Author(s)
  T.Kusama, S.Miyagawa, R.Nakai, M.Yamada, H.Sata, D.Fukuta, K.Matsunami, R.Shirakura
- Journal Title
  
  Transplant Proc 35(1)
  
  Pages: 529-530
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390414
[Journal Article] Effect of Various forms of C1 esterase inhibitor (C1-INH) and DAF on complement mediated xenogeneic cell lysis.2003
- Author(s)
  Fukuta Daisuke, Miyagawa Shuji, Yamada Mako, Matsunami Katsuyoshi, Kurihara Takashi, Shirasu Akio, Hattori Hiroyuki, Shirakura Ryota
- Journal Title
  
  Xenotransplantation 10(2)
  
  Pages: 132-141
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390377
[Journal Article] Effect of hybrid complement regulatory proteins on xenogeneic cells2003
- Author(s)
  Daisuke Fukuta, Shuji Miyagawa, Tomoko Kubo, Katsuyoshi Matsunami, Akio Shirasu, Hiroyuki Hattori, Ryota Shirakura
- Journal Title
  
  Biochem Biophys Res Commun 306(2-jun)
  
  Pages: 476-482
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390377
[Journal Article] Functional analysis of HSV-gC1 on swine endothelial cell.2003
- Author(s)
  K.Matsunami, S.Miyagawa, D.Fukuta, R.Shirakura
- Journal Title
  
  Transtrant Proc 35(1)
  
  Pages: 538-539
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390377
[Journal Article] 異種心臓移植モデルブタ-ヒヒ(又はアカゲザル)2003
- Author(s)
  福嶌教偉, 白倉良太
- Journal Title
  
  大動物臓器移植実験マニュアル2003
  
  Pages: 44-49
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370412
[Journal Article] Model of cardiac tranplantation using baboons or rhesus monkeys2003
- Author(s)
  N Fukushima, R Shirakura
- Journal Title
  
  Mannual of Large Animal Transplant Experiments
  
  Pages: 2-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370412
[Journal Article] Sensitivity to human serum of gammaretroviruses produced from pig endothelial cells transduced with glycosyltransferase genes.2003
- Author(s)
  Takashi Kurihara, Takayuki Miyazawa, Shuji Miyagawa, Keizo Tomonaga, Kenji Hazama, Junko Yamada, Ryota Shirakura, Yoshiharu Matsuura
- Journal Title
  
  Xenotransplantation 10
  
  Pages: 562-568
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390377
[Journal Article] Co-effect of HLA-G1 and Glycosyltransferases in Reducing NK cell-Mediated Pig Endothelial Cell Lysis2003
- Author(s)
  Shuji Miyagawa, Rie Nakai, Katsuyoshi Matsunami, Tamiko Kusama, Ryota Shirakura
- Journal Title
  
  Transplant Immunol 11
  
  Pages: 147-153
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390414
[Journal Article] Model of cardiac xenograft from pig to monkey2003
- Author(s)
  N Fukushima, R Shirakura
- Journal Title
  
  Mannual of Large Animal Transplant Experiments
  
  Pages: 44-49
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370412
[Journal Article] Studies of multiorgan procurement system from non heart beating donor2002
- Author(s)
  Fukushima N, Shirakura R, et al.
- Journal Title
  
  Transplantation Proceedings 34
  
  Pages: 2612-2614
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370412
[Journal Article] Studies of multiorgan procurement system form non heart beating donor2002
- Author(s)
  Fukushima N, Shirakura R, et al.
- Journal Title
  
  Transplant Proc 34
  
  Pages: 2612-2614
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370412
[Journal Article] A novel strategy for preventing PERV transmission to human cells by remodeling the viral envelope glycoprotein
- Author(s)
  Shuji Miyagawa, Shino Nakatsu, Kenji Hazama, Takatoshi Nakagawa, Akihiro Kondo, Katsuyoshi Matsunami, Junko Yamada, Takayuki Miyazawa, Ryota Shirakura
- Journal Title
  
  Xenotransplantation (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390377
[Journal Article] Molecular cloning of pigGnT-I and I.2 : An application to xenotransplantation Biochem
- Author(s)
  Katsuyoshi Matsunami, Shuji Miyagawa, Kenji Nakagawa, Otsuka Hideaki, Ryota Shirakura
- Journal Title
  
  Biochem Biophys Res Commun (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390414
[Journal Article] Molecular cloning of pigGnT-I and I.2 : An application to xenotransplantation
- Author(s)
  Katsuyoshi Matsunami, Shuji Miyagawa, Kenji Nakagawa, Otsuka Hideaki, Ryota Shirakura
- Journal Title
  
  Biochem Biophys Res Commun (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390377

1. FKUSHIMA Norihide (30263247)

# of Collaborated Projects: 21 results

# of Collaborated Products: 5 results
2. SAWA Yoshiki (00243220)

# of Collaborated Projects: 18 results

# of Collaborated Products: 0 results
3. NAKATA Seizoh (50116068)

# of Collaborated Projects: 14 results

# of Collaborated Products: 0 results
4. SAKAKIDA Satoru (90311753)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
5. MIYAGAWA Shuji (90273648)

# of Collaborated Projects: 11 results

# of Collaborated Products: 22 results
6. OKABE Masaru (30089875)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
7. KADOBA Keishi (00185886)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. TANIGUCHI Kazuhiro (90171842)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
9. NAKANO Susumu (70028653)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
10. MATSUDA Hikaru (00028614)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
11. ITO Toshinori (20231152)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
12. KANEKO Mitsunori (70169580)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
13. MATSUMIYA Goro (20314312)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
14. 川口章 (30195052)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
15. MURAKAMI Hiroshi

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
16. MIYAMOTO Yuji (80229898)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
17. TAKAHASHI Toshiki (50263257)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
18. ICHIKAWA Hajime (60303939)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
19. SHIMAZAKI Yasuhisa (60116043)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. MINAMI Masato (10240847)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. 川島康生 (10028425)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
22. FUKUTA Daisuke

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
23. TAKAMI Hiroshi (70236355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. KANEDA Yasufumi (10177537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. MASUDA Junichi (70173747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. IMAGAWA Hiroshi (90273622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. MASAI Takafumi (30273650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. NISHIMURA Motonobu (90291442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. OHTAKE Shigeaki (50243209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. TAKANO Hiroshi (70346196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. KITAGAWA Toru (40314322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 木下順弘 (30195341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 松若良介 (00243238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 井原義人 (70263241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. NAKAGAMI Tatsuyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. SHIGEHISA Tamotsu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. HAYSHI Kazuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. KONDO Akihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 光野正孝

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIRAKURA Ryota 白倉 良太

白倉 良太 シラクラ リヨウタ

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Downregulation of the NK cell activity on xenograftPrincipal Investigator

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局所遺伝子導入による移植後動脈硬化症に対する特異的治療法開発Principal Investigator

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アロ抗原の存続とAICDの有無による移植免疫寛容の臨床診断法確立への予備的研究Principal Investigator

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Green miceを用いた移植免疫寛容誘導に関わる新規遺伝子クローニングの試みPrincipal Investigator

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The strategy for inhibiting NK cell activity by gene technologyPrincipal Investigator

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異種移植における新糖鎖抗原の探究Principal Investigator

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SHIRAKURA Ryota 白倉良太

白倉良太シラクラリヨウタ