HIROTA Hiroshi 廣田洋

… Alternative Names

廣田洋ヒロタヒロシ

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Researcher Number	00126153
Affiliation (based on the past Project Information) *help	2016: 国立研究開発法人理化学研究所, 理研-KRIBB連携研究ユニット, 客員研究員 2015: 国立研究開発法人理化学研究所, その他部局等, 研究員 2014: 理化学研究所, 理研-KRIBB連携研究ユニット, 客員研究員 2013 – 2014: 独立行政法人理化学研究所, 理研-KRIBB連携研究ユニット, 客員研究員 2011 – 2012: 独立行政法人理化学研究所, 支援促進チーム, 協力研究員 … More 2010 – 2012: 独立行政法人理化学研究所, 支援促進チーム, 特任職員 2009: 独立行政法人理化学研究所, 長田抗生物質研究室, 特任職員 2006: 独立行政法人理化学研究所, タンパク質構造・機能研究グループ, プロジェクト副ディレクター 2005 – 2006: 理化学研究所, 蛋白質構造・機能研究グループ, 副ディレクター(研究職) 2002 – 2003: 理化学研究所, タンパク質構造機能研究グループ, プロジェクト副ディレクター(研究職) 1991: 東京大学, 理学部, 助手 1989: 東京大学, 理学部, 助手 Less
Review Section/Research Field	Principal Investigator Science and Engineering / 天然物有機化学 Except Principal Investigator Applied microbiology / Animal physiology/Animal behavior / 動物生理・代謝 / Fisheries chemistry / Bio-related chemistry / Living organism molecular science
Keywords	Principal Investigator タンパク質 / 超微量 / スクリーニング / ペプチド / 分子間相互作用解析 / 自己組織化膜 / MALDI / 質量分析法 / 2次元NMR / 骨格転移反応 / 配触媒転移 / 立体選択性 / セスキテルペン … More Except Principal Investigator … More vanadium / 立体構造 / 金属結合タンパク質 / EST / NMR / ESR / バナジウム / ホヤ / Toxadocial A / Nazumamide A / シグナル伝達 / イネいもち病菌 / 国際研究者交流 / 系統樹 / 天然物化学 / 多様性 / 中国横断山脈 / SS bonds / redox / cell culture / three dimensional structure / metal binding proteins / ascidian / 円二色性スペクトル / SS結合 / 酸化還元 / 細胞培養 / structural biology / coordination chemistry / accumulation mechanism / ascidians / 解離定数 / 構造生物学 / 錯体化学 / 濃縮機構 / Marine Sponges / Serine Proteases / Trypsin / Thrombin / Protease Inhibitors / Marine Invertebrates / テトラペプチド / nazumomide A / セリンプロテア-ゼ / 硫酸コステル / toxadocial A / 海綿動物 / 海綿 / セリンプロテアーゼ / トリプシン / トロンビン / 酵素阻害 / 海洋無脊椎動物 / ゲノム / 菌類 / 応用微生物 / 抗生物質 / 二次代謝 / 糸状菌ゲノム / 中国 / 農薬 / 生合成 / 天然化合物 / ITS / セスキテルペン / 多様化 / Ligularia属 / 横断山脈 Less

Huge number of secondary metabolism genes in fungal genomes: roles and regulation by environmental signal transduction pathways
- Principal Investigator
  
  Motoyama Takayuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied microbiology
- Research Institution
  Institute of Physical and Chemical Research
Chemical and genetic study of plant evolution and speciation in the Hengduan Mountains of China
- Principal Investigator
  
  KURODA Chiaki
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Rikkyo University
Fungal silent secondary metabolite gene cluster activation by disturbance of environmental responses
- Principal Investigator
  
  MOTOYAMA Takayuki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied microbiology
- Research Institution
  The Institute of Physical and Chemical Research
Study on Speciation Mechanisms of Plants in the Hengduan Mountains of China -An Approach Examining Their Chemical and Genetic Diversities-
- Principal Investigator
  
  KURODA Chiaki
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Rikkyo University
質量分析法を用いた超微量分子間相互作用スクリーニング法の開発Principal Investigator
- Principal Investigator
  
  廣田洋
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  The Institute of Physical and Chemical Research
Molecular physiological study on Vanabins that are key factors for metal accumulation mechanisms
- Principal Investigator
  
  MICHIBATA Hitoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Animal physiology/Animal behavior
- Research Institution
  Hiroshima University
Molecular Physiology of the Highly-Selective Bioaccumulation of Metal Ions
- Principal Investigator
  
  MICHIBATA Hitoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  動物生理・代謝
- Research Institution
  HIROSHIMA UNIVERSITY
Search for serine protease inhibitors from marine invertebrates.
- Principal Investigator
  
  FUSETANI Nobuhiro
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  University of Tokyo
高歪みセスキテルペンの反応性および新奇骨格への変換反応の研究Principal Investigator
- Principal Investigator
  
  廣田洋
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  天然物有機化学
- Research Institution
  The University of Tokyo

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] 演習で学ぶ有機化合物のスペクトル解析2010
- Author(s)
  横山泰・廣田洋・石原晋次
- Total Pages
  186
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-21404009
[Journal Article] Structure-activity relationships of terpendole E and its natural derivatives.2017
- Author(s)
  Nagumo Y, Hayashi T, Hirota H, Aono H, Kawatani M, Osada H, Usui T
- Journal Title
  
  ChemistrySelect
  
  Volume: 2 Issue: 4 Pages: 1533-1536
- DOI
  10.1002/slct.201602015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02445, KAKENHI-PROJECT-26450109, KAKENHI-PROJECT-26430140, KAKENHI-PLANNED-17H06412
[Journal Article] New Eremophilane-type Sesquiterpnens from Ligularia cymbulifera2017
- Author(s)
  T. Kato, H. Hirota, C. Kuroda, X. Gong, A. Ohsaki
- Journal Title
  
  Natural Product Communications
  
  Volume: 12
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25303010
[Journal Article] Two new diterpenoids from Salvia przewarskii2016
- Author(s)
  H. Tsukada, H. Kawabe, A. Ohtaka, Y. Saito, Y. Okamoto, M. Tori, H. Kagechika, H. Hirota, X. Gong, C. Kuroda, A. Ohsaki
- Journal Title
  
  Natural Product Communications
  
  Volume: 11 Pages: 159-161
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25303010
[Journal Article] Synthesis and NMR spectroscopic elucidation of four diastereoisomers of oxygenated bisabolane side chain2015
- Author(s)
  M. Hirai, R. Miyazaki, K. Mitsui, K. Kiuchi, H. Onuki, H. Hirota, C. Kuroda
- Journal Title
  
  Helvetica Chimica Acta
  
  Volume: 98 Issue: 8 Pages: 1035-1060
- DOI
  10.1002/hlca.201400395
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25303010
[Journal Article] Detection of oxygen addition peaks for terpendole E and related indole-diterpene alkaloids in a positive-mode ESI-MS2014
- Author(s)
  Hongo, Y., Nakamura, T., Takahashi, S., Motoyama, T., Hayashi, T., Hirota, H., Osada, H., and Koshino, H.
- Journal Title
  
  Journal of Mass Spectrometry
  
  Volume: 49 Issue: 12 Pages: 537-542
- DOI
  10.1038/ja.2014.80
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23580125, KAKENHI-PROJECT-24380052, KAKENHI-PUBLICLY-25108721
[Journal Article] Terpendole E and its derivative inhibit STLC - and GSK-1-resistant Eg52014
- Author(s)
  Tarui Y, Chinen T, Nagumo Y, Motoyama T, Hayashi T, Hirota H, Muroi M, Ishii Y, Kondo H, Osada H, Usui T.
- Journal Title
  
  ChemBioChem
  
  Volume: (In press) Issue: 7 Pages: 934-938
- DOI
  10.1002/cbic.201300808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J01199, KAKENHI-PROJECT-23580125, KAKENHI-PUBLICLY-24102536, KAKENHI-PROJECT-24710244
[Journal Article] Detection of oxygen addition peaks for terpendole E and related indole-diterpene alkaloids in a positive mode ESI-MS2014
- Author(s)
  Hongo Y., Nakamura T., Takahashi S., Motoyama T., Hayashi T., Hirota H., Osada H., Koshino H.
- Journal Title
  
  J. Mass Spectrom.
  
  Volume: 49 Issue: 6 Pages: 537-542
- DOI
  10.1002/jms.3360
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24580168, KAKENHI-PROJECT-24619011, KAKENHI-PROJECT-26450109
[Journal Article] Diversity in Furanoeremophilane Composition Produced by <i>Ligularia</i> Species (Asteraceae) in the Hengduan Mountains Area of China2014
- Author(s)
  黒田智明、花井　亮、通　元夫、岡本育子、齋藤義紀、永野　肇、大崎愛弓、廣田　洋、河原孝行、Xun Gong
- Journal Title
  
  Journal of Synthetic Organic Chemistry, Japan
  
  Volume: 72 Issue: 6 Pages: 717-725
- DOI
  10.5059/yukigoseikyokaishi.72.717
- NAID
  130004548619
- ISSN
  0037-9980, 1883-6526
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25303010
[Journal Article] The First Isolation of Furanoeremophilane from Ligularia nelumbifolia2014
- Author(s)
  H. Hirota, Y. Horiguchi, S. Kawaii, R. Hanai, X. Gong, C. Kuroda
- Journal Title
  
  Natural Product Communications
  
  Volume: 9 Pages: 325-327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25303010
[Journal Article] Terpendole E, a kinesin Eg5 inhibitor, is a key biosynthetic intermediate of indole-diterpenes in the producing fungus Chaunopycnis alba2012
- Author(s)
  T. Motoyama et al
- Journal Title
  
  Chem. Biol.
  
  Volume: 19 Issue: 12 Pages: 1611-1619
- DOI
  10.1016/j.chembiol.2012.10.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21404009, KAKENHI-PROJECT-23580125, KAKENHI-PROJECT-24248022
[Journal Article] Chemical and GeneticStudy of Ligularia duciformis and RelatedSpecies in Sichuan and Yunnan Provinces ofChina2012
- Author(s)
  H. Nagano, R. Hanai, H. Yamada, M.Matsushima, Y. Miura, T. Hoya, M. Ozawa,M. Fujiwara, H. Kodama, A. Torihata, H.Onuki, Y. Nezu, S. Kawai, M. Yamazaki, H.Hirota, Y. Saito, M. Tori, A. Ohsaki, X.Gong, C. Kuroda
- Journal Title
  
  Chem. Biodiversity
  
  Volume: 9 Pages: 789-805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21404009
[Journal Article] Four new bisabolane-type sesquiterpenes from Ligularia lankongensis2012
- Author(s)
  H. Hirota et al
- Journal Title
  
  Nat. Prod. Commun.
  
  Volume: 7 Pages: 451-454
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21404009
[Journal Article] Solution structure and fluctuation of the Mg2+-bound form of calmodulin C-terminal domain2011
- Author(s)
  W.Ohashi, H.Hirota, T.Yamazaki
- Journal Title
  
  Protein Science
  
  Volume: 20 Issue: 4 Pages: 690-701
- DOI
  10.1002/pro.598
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21404009
[Journal Article] Isolation of Salsolinol, a Tetrahydroisoquinoline Alkaloid, from the Marine Sponge Xestospongia cf.vansoesti as a Proteasome Inhibitor2010
- Author(s)
  Y.Nagasawa, R.Ueoka, R.Yamanokuchi, N.Horiuchi, T.Ikeda, H.Rotinsulu, R.E.P.Mangindaan, K.Ukai, H.Kobayashi, M.Namikoshi, H.Hirota, H.Yokosawa, S.Tshukamoto
- Journal Title
  
  Chem.Pharm.Bull.
  
  Volume: 59 Pages: 287-290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21404009
[Journal Article] Notoamide O, a Structurally Unprecedented Prenylated Indole Alkaloid, and Notoamides P-R from a Marine-Derived Fungus, Aspergillus sp.2010
- Author(s)
  S.Tsukamoto, H.Umaoka, K.Yoshikawa, T.Ikeda, H.Hirota
- Journal Title
  
  J.Nat.Prod.
  
  Volume: 73 Pages: 1438-1440
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21404009
[Journal Article] Zinc Suppresses T_h17 Development via Inhibition of STAT3 Activation2010
- Author(s)
  C.Kitabayashi, T.Fukada, M.Kanamoto, W.Ohashi, S.Hojyo, T.Atsumi, N.Ueda, I.Azuma, H.Hirota, M.Murakami, T.Hirano
- Journal Title
  
  Int.Immunol.
  
  Volume: 22 Pages: 375-386
- NAID
  10027579935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21404009
[Journal Article] Solution Structure of Polytheonamide B, a Highly Cytotoxic Nonribosomal Polypeptide from Marine Sponge2010
- Author(s)
  T.Hamada, S.Matsunaga, M.Fujiwara, K.Fujita, H.Hirota, R.Schmucki, P.Guntert, N.Fusetani
- Journal Title
  
  J.Am.Chem.Soc.
  
  Volume: 132 Pages: 12941-12945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21404009
[Journal Article] Isolation of Antipodal(-)-Versicolamide B and Notoamides L-N from a Marine-Derived Aspergillus sp.2009
- Author(s)
  S.Tsukamoto, T.Kawabata, H.Kato, T.J.Greshock, H.Hirota, T.Ohta, R.M.Williams
- Journal Title
  
  Org.Lett. 11
  
  Pages: 1297-1300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21404009
[Journal Article] Chemical and genetic differentiation of Ligularia hodgsonii in Japan and China2009
- Author(s)
  A.Torihata, X.Chao, C.Kuroda, R.Hanai, H.Hirota, X.Gong
- Journal Title
  
  Chem.& Biodiversity 6
  
  Pages: 2184-2191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21404009
[Journal Article] A Lichen Substance as an Antiproliferative Compound against HL-60 Human Leukemia Cells : 16-O-Acetyl-leucotylic Acid Isolated from Myelochroa aurulenta2009
- Author(s)
  T.Tokiwano, H.Satoh, T.Obara, H.Hirota, Y.Yoshizawa, Y.Yamamoto
- Journal Title
  
  Biosci.Biotechnol.Biochem 73
  
  Pages: 2525-2527
- NAID
  10027548202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21404009
[Journal Article] The Effect of Sodium Dodecyl Sulfate and Anion-Exchange Silica Gel on Matrix-Assisted Laser Desorption/Ionization Mass Spectrometric Analysis of Proteins2009
- Author(s)
  M.Asanuma, S.Fukuzawa, T.Matsuda, H.Hirota
- Journal Title
  
  Rapid Commun. Mass Spectrom 23
  
  Pages: 1647-1653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21404009
[Journal Article] Highly Coplanar Polythiophenes with -C≡CR Side Chains : Self-Assembly, Linear and Nonlinear Optical Properties, and Piezochromism2009
- Author(s)
  T.Yamamoto, T.Sato, T.Iijima, M.Abe, H.Fukumoto, T.Koizumi, M.Usui, Y.Nakamura, T.Yagi, H.Tajima, T.Okada, S.Sasaki, H.Kishida, A.Nakamura, T.Fukuda, A.Emoto, H.Ushijima, C.Kurosaki, H.Hirota
- Journal Title
  
  Bull.Chem.Soc.Jpn. 82
  
  Pages: 896-909
- NAID
  10025126539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21404009
[Journal Article] Isolation of Notoamide E, a Key Precursor in the Biosynthesis of Prenylated Indole Alkaloids in a Marine-Derived Fungus, Aspezgillus sp.2009
- Author(s)
  S.Tsukamoto, H.Kato, T.J.Greshock, H.Hirota, T.Ohta, R.M.Williams
- Journal Title
  
  J.Am.Chem.Soc. 131
  
  Pages: 3834-3835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21404009
[Presentation] 中国産Salvia属植物の成分研究2017
- Author(s)
  桑田佳奈，川邊浩史，Xun Gong　廣田　洋，大﨑愛弓
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] Securinega suffruticosaの成分2016
- Author(s)
  児玉佳之，久保美和，福山愛保，廣田洋，大崎愛弓
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] Ligularia cymburifera の成分探索2016
- Author(s)
  加藤隆大、廣田洋、黒田智明、大崎愛弓
- Organizer
  日本生薬学会第６３回年会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2016-09-24
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] Portulaca pilosaの成分2016
- Author(s)
  原惠美，廣田洋，大崎愛弓
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] Securinega suffruticosa の成分探索2016
- Author(s)
  児玉佳之、久保美和、松崎佳一、福山愛保、廣田洋、大崎愛弓
- Organizer
  日本生薬学会第６３回年会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2016-09-24
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] 中国産Salvia maximowicziana およびS. grandifoliaの成分研究2016
- Author(s)
  川邊浩史、廣田洋、Gong Xun、大崎愛弓
- Organizer
  第２１回天然薬物の開発と応用シンポジウム
- Place of Presentation
  千葉大学薬学部（千葉県千葉市）
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] New Erythrina Alkaloids from Erythrina velutina2016
- Author(s)
  K. Todoroki, H. Hirota, A. Ohsaki
- Organizer
  International Symposium on Natural Products for the Future 2016
- Place of Presentation
  徳島文理大学（徳島県徳島市）
- Year and Date
  2016-09-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] Chemical Constituents of Salvia Species Collected in Sichuan Province of China2016
- Author(s)
  K. Kuwada, H. Kawabe, Y. Saito, Y. Okamoto, M. Tori, X. Gong, H. Hirota, A. Ohsaki
- Organizer
  International Symposium on Natural Products for the Future 2016
- Place of Presentation
  徳島文理大学（徳島県徳島市）
- Year and Date
  2016-09-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] 中国産Salvia grandifoliaおよびSalvia sp.の成分研究2016
- Author(s)
  川邊浩史、小宮山哲平、齋藤義紀、岡本育子、通元夫、黒田智明、影近弘之、Xun Gong、廣田洋、大崎愛弓
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] 中国雲南省産Ligularia lankongensisの高度に酸化されたビサボラン化合物2015
- Author(s)
  齋藤義紀、岡本育子、花井　亮、平井美咲、松尾洋介、田中　隆、Xun Gong、廣田　洋、黒田智明
- Organizer
  第59回香料テルペンおよび精油化学に関する討論会
- Place of Presentation
  近畿大学（大阪府東大阪市）
- Year and Date
  2015-09-05
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] 天然物有機化学から天然物科学へ2014
- Author(s)
  廣田　洋
- Organizer
  第4回天然物パワーシンポジウム
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2014-07-19
- Invited
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] ESI-MS分析で観測されるTerpendoleイオンの酸化とその抑制2013
- Author(s)
  本郷やよい、中村健道、高橋俊哉、本山高幸、林敏明、廣田洋、長田裕之、越野広雪
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  東北大学（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-23580125
[Presentation] 糸状菌Magnaporthe oryzaeの二成分情報伝達系攪乱によるテヌアゾン酸の生産誘導2013
- Author(s)
  尹忠銖，本山高幸，林敏明，廣田洋，長田裕之
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  東北大学（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-23580125
[Presentation] 糸状菌の二成分情報伝達系攪乱により生産誘導されるポリケタイド化合物の生合成遺伝子クラスターの同定2013
- Author(s)
  本山高幸、林敏明、廣田洋、長田裕之
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  東北大学（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-23580125
[Presentation] 糸状菌Fusarium sp. RK97-94のルシラクタエン生合成遺伝子クラスター中のトランスポーターおよびメチル基転移酵素遺伝子の機能解析2013
- Author(s)
  加藤翔、本山高幸、林敏明、廣田洋、田中彰、安藤直子、鎌倉高志、長田裕之
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  東北大学（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-23580125
[Presentation] イネいもち病菌の二成分情報伝達系攪乱によるポリケタイド化合物生産誘導2012
- Author(s)
  本山高幸，林敏明，廣田洋，長田裕之
- Organizer
  第12回糸状菌分子生物学コンファレンス
- Place of Presentation
  愛知県産業労働センターウインクあいち（愛知県名古屋市）
- Data Source
  KAKENHI-PROJECT-23580125
[Presentation] イネいもち病菌の二成分情報伝達系攪乱によるPK-NRP融合化合物生産誘導2012
- Author(s)
  尹忠銖，本山高幸，林敏明，廣田洋，長田裕之
- Organizer
  第12回糸状菌分子生物学コンファレンス
- Place of Presentation
  愛知県産業労働センターウインクあいち（愛知県名古屋市）
- Data Source
  KAKENHI-PROJECT-23580125
[Presentation] ビサボラン誘導体の合成とその立体化学2012
- Author(s)
  宮崎瑠璃奈、北澤美悠、廣田洋、黒田智明
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶應義塾大学(横浜市)
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-21404009
[Presentation] 糸状菌の二成分情報伝達系攪乱による二次代謝産物生産誘導2012
- Author(s)
  本山高幸、林敏明、廣田洋、長田裕之
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都女子大学（京都府）
- Data Source
  KAKENHI-PROJECT-23580125
[Presentation] ビサボラン型セスキテルペンの8位の立体化学解明に向けた合成2011
- Author(s)
  宮崎瑠璃奈・三ツ井香菜・石川夏織・廣田洋・大貫裕之・黒田智明
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-21404009
[Presentation] ルシラクタエン生合成遺伝子クラスターの解析2011
- Author(s)
  田中彰、本山高幸、林敏明、廣田洋、安藤直子、長田裕之
- Organizer
  第11回糸状菌分子生物学コンファレンス
- Place of Presentation
  東京大学
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-21404009
[Presentation] キク科Ligularia duciformsおよび関連種の化学的遺伝的多様性2011
- Author(s)
  永野肇・花井亮・山田ひろか・松嶋美佳・三浦唯・藤原美保・大貫裕之・廣田洋・齋藤義紀・通元夫・大崎愛弓・〓洵・黒田智明
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪国際交流センター(大阪市)
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-21404009
[Presentation] キク科Ligulariaduciformisおよび関連種の化学的遺伝的多様性2011
- Author(s)
  永野肇・花井亮・山田ひろか・松嶋美佳・三浦唯・藤原美保・大貫裕之・廣田洋・齋藤義紀・通元夫・大崎愛弓・〓洵・黒田智明
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪国際交流センター)
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-21404009
[Presentation] ルシラクタエン生合成遺伝子クラスターの解析2011
- Author(s)
  田中彰、本山高幸、林敏明、廣田洋、安藤直子、長田裕之
- Organizer
  第11回糸状菌分子生物学コンファレンス
- Place of Presentation
  東京大学弥生講堂（東京都）
- Data Source
  KAKENHI-PROJECT-23580125
[Presentation] 中国産キク科植物Ligularla lankongensisの化学成分とその多様性2011
- Author(s)
  堀口友里恵・黒田智明・花井亮・Gong Xun・川井悟・廣田洋
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-21404009
[Presentation] ビサボラン型セスキテルペンの側鎖の立体化学解明に向けた合成研究2010
- Author(s)
  宮崎瑠璃奈・三ツ井香菜・木内浩太・黒田智明・大貫裕之・廣田洋
- Organizer
  第54回香料テルペンおよび精油化学に関する討論会
- Place of Presentation
  甲府
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-21404009
[Presentation] Stereochemistry of bisabolane sesquiterpenes in Ligularia lankongensis2010
- Author(s)
  R.Miyazaki ; K.Mitsui ; C.Kuroda ; H.Onuki ; H.Hirota
- Organizer
  The 2010 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, USA
- Year and Date
  2010-12-18
- Data Source
  KAKENHI-PROJECT-21404009
[Presentation] 中国横断山脈産 Ligularia duciformis およびL.oligonema の成分、塩基配列、生育環境2009
- Author(s)
  永野肇・松嶋美佳・山田ひろか・大崎愛弓・小沢正晃・通元夫・廣田洋・大貫裕之・鳥畑厚志・花井亮・黒田智明・襲洵
- Organizer
  第53回香料テルペンおよび精油化学に関する討論会
- Place of Presentation
  生駒
- Year and Date
  2009-11-08
- Data Source
  KAKENHI-PROJECT-21404009
[Presentation] Ligularia kanaitzensis および関連種におけるフラノエレモフィラン生産と生態2009
- Author(s)
  黒田智明, 鳥畑厚志, 花井亮, 晃殉, 齋藤義紀, 岡本育子, 立川佳奈, 松尾幸恵, 渡邊亜貴, 谷尾由衣, 馬場麻規子, 通元夫, 松嶋美佳, 永野肇, 廣田洋, 襲洵
- Organizer
  第51回天然有機化合物討論会
- Place of Presentation
  名古屋
- Year and Date
  2009-10-08
- Data Source
  KAKENHI-PROJECT-21404009
[Presentation] 日本産と中国産 Ligularia hodgsonii の成分および塩基配列における共通点と相違点2009
- Author(s)
  黒田智明・鳥畑厚志・晃殉・花井亮・廣田洋・襲洵
- Organizer
  第53回香料テルペンおよび精油化学に関する討論会
- Place of Presentation
  生駒
- Year and Date
  2009-11-08
- Data Source
  KAKENHI-PROJECT-21404009
[Presentation] DIFFERENCE IN CHEMICAL COMPOSITION OF SOME LIGULARIA SPECIES BETWEEN YUNNAN AND SICHUAN2009
- Author(s)
  C.Kuroda, R.Hanai, H.Nagano, M.Tori, A.Ohsaki, H.Hirota, X.Gong
- Organizer
  IUPAC 5th International Symposium on Novel Materials and Synthesis(NMS-V)
- Place of Presentation
  上海
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21404009
[Presentation] Furanoeremophilanes in Ligularia hodgsonii in Japan and China2009
- Author(s)
  X.Chao, A.Torihata, C.Kuroda, R.Hanai, H.Hirota, X.Gong
- Organizer
  IUPAC 5th International Symposium on Novel Materials and Synthesis(NMS-V)
- Place of Presentation
  上海
- Year and Date
  2009-10-20
- Data Source
  KAKENHI-PROJECT-21404009
[Presentation] 糸状菌Fusarium sp. RK97-94のルシラクタエン生合成遺伝子クラスターの解析
- Author(s)
  加藤翔、本山高幸、林敏明、廣田洋、鎌倉高志、長田裕之
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23580125
[Presentation] ４種のビサボラン側鎖異性体の合成とそのNMR
- Author(s)
  平井美咲、廣田　洋、黒田智明
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学（愛知）
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] 8, 10位の酸化されたビサボランモデル化合物の合成とNMRスペクトル
- Author(s)
  平井美咲、廣田　洋、黒田智明
- Organizer
  第58回香料テルペンおよび精油化学に関する討論会
- Place of Presentation
  和歌山大学（和歌山市）
- Year and Date
  2014-09-20 – 2014-09-21
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] 糸状菌の情報伝達系攪乱による二次代謝活性化及び生産誘導される化合物の解析
- Author(s)
  本山高幸、尹忠銖、二村友史、廣田洋、長田裕之
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23580125
[Presentation] Ligularia lankongensisから単離されたビサボラン型セスキテルペンの合成研究
- Author(s)
  高木広和、廣田　洋、黒田智明
- Organizer
  日本化学会第94春季年会
- Place of Presentation
  名古屋大学（愛知）
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] 糸状菌 Fusarium sp. RK97-94 のルシラクタエン生合成遺伝子クラスター中のメチル基転移酵素遺伝子 luc1 とトランスポーター遺伝子 luc4 の機能解析
- Author(s)
  加藤翔、本山高幸、廣田洋、鎌倉高志、長田裕之
- Organizer
  第13回糸状菌分子生物学コンファレンス
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-23580125
[Presentation] 酸素官能基化されたビサボラン型化合物の合成と8, 10位の立体化学
- Author(s)
  高木広和・平井美咲・宮崎瑠璃奈・廣田　洋・黒田智明
- Organizer
  香料テルペンおよび精油化学に関する討論会
- Place of Presentation
  埼玉大学（さいたま）
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] 酸素官能基化されたビサボラン化合物の合成とNMRスペクトルによる立体構造の区別
- Author(s)
  平井美咲、高木広和、廣田　洋、黒田智明
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学（千葉県船橋市）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25303010
[Presentation] Functional analysis of the luc1 and luc4 genes in the lucilactaene biosynthesis gene cluster of the producing fungus Fusarium sp. RK97-94
- Author(s)
  Sho Kato, Takayuki Motoyama, Hiroshi Hirota, Takashi Kamakura, Hiroyuki Osada
- Organizer
  KRIBB-RIKEN Chemical Biology Joint Symposium
- Place of Presentation
  Ochang, Korea
- Data Source
  KAKENHI-PROJECT-23580125

1. MICHIBATA Hitoshi (00111740)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. KURODA Chiaki (40158887)

# of Collaborated Projects: 2 results

# of Collaborated Products: 26 results
3. HANAI Ryo (30287916)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. TORI Motoo (90163956)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
5. SAITO Yoshinori (30441588)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. OHSAKI Ayumi (50161360)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
7. MOTOYAMA Takayuki (70291094)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
8. UEKI Tatsuya (10274705)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NAGANO Hajime (10114919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. KAWAHARA Takayuki (70353654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. FUSETANI Nobuhiro (70012010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MATSUNAGA Shigeki (60183951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KANAMORI Kan (00019001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HAMADA Toshiyuki (40321799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 兼目裕充 (10399438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 岡本育子 (30598610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. 八百板康範 (40296017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 中島勝幸 (80299338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 臼杵克之助 (30244651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. GONG Xun

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
21. HAO Xiaojiang

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 長田裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 高橋俊哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIROTA Hiroshi 廣田 洋

廣田 洋 ヒロタ ヒロシ

Research Projects

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Co-Researchers

Huge number of secondary metabolism genes in fungal genomes: roles and regulation by environmental signal transduction pathways

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Chemical and genetic study of plant evolution and speciation in the Hengduan Mountains of China

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Fungal silent secondary metabolite gene cluster activation by disturbance of environmental responses

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Study on Speciation Mechanisms of Plants in the Hengduan Mountains of China -An Approach Examining Their Chemical and Genetic Diversities-

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質量分析法を用いた超微量分子間相互作用スクリーニング法の開発Principal Investigator

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Molecular physiological study on Vanabins that are key factors for metal accumulation mechanisms

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Molecular Physiology of the Highly-Selective Bioaccumulation of Metal Ions

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Search for serine protease inhibitors from marine invertebrates.

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高歪みセスキテルペンの反応性および新奇骨格への変換反応の研究Principal Investigator

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[Book] 演習で学ぶ有機化合物のスペクトル解析2010

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[Journal Article] Structure-activity relationships of terpendole E and its natural derivatives.2017

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[Journal Article] New Eremophilane-type Sesquiterpnens from Ligularia cymbulifera2017

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[Journal Article] Two new diterpenoids from Salvia przewarskii2016

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[Journal Article] Synthesis and NMR spectroscopic elucidation of four diastereoisomers of oxygenated bisabolane side chain2015

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HIROTA Hiroshi 廣田洋

廣田洋ヒロタヒロシ