MATSUNAGA Shigeki 松永茂樹

Researcher Number	60183951
Affiliation (based on the past Project Information) *help	2015 – 2021: 東京大学, 大学院農学生命科学研究科(農学部), 教授 2012 – 2016: 東京大学, 農学生命科学研究科, 教授 2007 – 2012: The University of Tokyo, 大学院・農学生命科学研究科, 教授 2006: The University of Tokyo, Graduate School of Agricultural and Life Sciences, Professor, 大学院農学生命科学研究科, 教授 2004 – 2005: 東京大学, 大学院・農学生命科学研究科, 教授 … More 1996 – 2003: 東京大学, 大学院・農学生命科学研究科, 助教授 1995: 東京大学, 農学部, 助教授 1992 – 1994: University of Tokyo, Faculty of Agriculture, Assistant, 農学部, 助手 Less
Review Section/Research Field	Principal Investigator Fisheries chemistry / Fisheries chemistry / Aquatic life science / Science and Engineering / Science and Engineering / Aquatic life science / Fisheries chemistry / Bioorganic chemistry / Biological Sciences Except Principal Investigator Fisheries chemistry … More / Basic veterinary science/Basic zootechnical science / Aquatic life science / Science and Engineering / Basic Section 40040:Aquatic life science-related / Fisheries chemistry / General pharmacology / Biological Sciences Less
Keywords	Principal Investigator 海綿 / 構造決定 / カイメン / 細胞毒性 / 海洋生物 / 単離 / 海産無脊椎動物 / ペプチド / Vibrio anguillarum / structure elucidation … More / polytheonamide / sponge / 細胞周期 / 抗腫瘍性 / 天然物化学 / イオンチャネル / ウスボヤ科 / 酵素阻害 / 生育阻害 / 酵母 / 抗腫瘍 / マクロライド / 海綿動物 / Mycale / ロテノン / パーキンソン病 / 精製 / パーキンソン病モデル / 細胞保護作用 / がん細胞 / 培養細胞 / メタボローム / 共栄微生物 / Theonella swinhoei / 培養 / 生産者 / 共生微意生物 / 物質生産 / ケミカルコミュニケーション / 共生微生物 / 微生物 / 共生 / 抗がん剤 / 探索研究 / Fucci2細胞 / spectral analysis / serinolipid / antimicrobial / fish pathogenic bacteria / Didemnidae / tunicate / Aeromonas hydrophila / 二次元NMR / ホヤ / セルノリピッド / 機器分析 / セリノリピド / 抗菌性 / 魚病細菌 / Vibno anguillarum / 群体ボヤ / ion channel / channel / amino acid / peptide / marine sponge / イオンチャンネル / 電気生理 / アミノ酸 / 構造解析 / elucidation / structure / isolation / invertebrates / marine / antifungal / 無脊椎動物 / 海洋 / 抗カビ性 / juhibitor / galactosidase / glycosidase / coelenterate / グルコシダーゼ / 阻害剤 / ガウクトシダーゼ / 阻害物質 / ガラクトシダーゼ / グリコシダーゼ / 腔腸動物 / 生理活性物質 / フトツノザメ / 海洋天然物 / 予防 / 生活習慣病 / 脂肪滴 / マクロファージ / 前駆脂肪細胞 / 分化誘導 / 脂肪細胞 / 探索 / 海洋微生物 / 抗がん性 / 3Y1細胞 / 生物活性 / 組換え微生物 / 生合成 / テルペン / マラリア / 枯草菌 / 遺伝子操作 / 抗菌活性 / テルペン生合成 / 活性物質 / 抗腫瘍活性 / 生育回復 / 変異 / 遺伝子導入 / 遺伝子導入酵母 / モデル / 化学合成 / マトリックスメタロプロテアーゼ / ガン転移 / セリノリピッド / シアリダーゼ / アルカロイド / Xestospongia / ヒストンデアセチセチラーゼ / Boc化 / メーヤワイン試薬 / 加水分解 / 脱重合 / アクチン / 抗体 / mycalolide / チャンネル / ポリペプチド / Theonella … More Except Principal Investigator 海綿 / カルモジュリン / 細胞毒性 / calmodulin / actin / 平滑筋 / アクチン / ペプチド / 酵素阻害 / Botryococcus braunii / 炭化水素 / 海洋天然化合物 / 海洋無脊椎動物 / 脂肪酸 / バイオ燃料 / pectenotoxin 2 / biology / ペクテノトキシン / カルシウムチャネル / marine sponge / タンパク質脱リン酸化酵素 / カリクリン / 生物活性物質 / Cytotoxic / Toxadocial A / Nazumamide A / セリンプロテアーゼ / 天然物化学 / ケミカルバイオロジー / トリテルペン / 生合成 / 微細藻類 / Farnesol / Stellettamide / イソプレノイド / ポリペプチド / aldehyde / hydrocarbon / biopolymer / colony / 群体 / バイオポリマー / 生物活性リガンド / 分子社会学 / 化学コミュニケーション / メタゲノム解析 / 共生微生物 / 海洋天然物 / アルケン / バイオエネルギー / n-アルカン / n-アルケン / photodecarboxylase / 生合成酵素 / 直鎖アルケン / 直鎖アルカン / Metaloprotease inhibitor / Geranyltransferase / Voltage dependent Ca2+ channels / Calmodulin / Metabolite of cholesterol / Marine natural products / 細胞増殖 / 動脈硬化 / コレステロール代謝 / イソプレノイド化合物 / メタロプロテアーゼ阻害剤 / ゲラニルトランスフェラーゼ / 電位依存性Caチャネル / コレステロール生合成系 / ファルネソール / ステレッタマイド / Structure elucidation / Bioactive / Biomedical / Sponge / Deep-Sea / タカシガニ漁 / 酵素阻害活性 / 抗菌・抗カビ性 / 構造解析 / マクロライド / セスタテルペン / theopederin / 漁業混獲物 / 深海海綿 / 構造決定 / 生物活性 / 医薬素材 / 深海 / bisteonellide A / swinholide A / mycalolide B, and / depolimerization / ウイルス感染 / 腎上皮細胞 / peptides / serine protease / protein phosphatase / calyculin / triterpene / sponges / invertebrates / 抗菌性 / ソフトコーラル / 3-アルキルピリジン / カルモジュリン阻害物質 / IP_3レセプター阻害剤 / イソマラブリカントリテルペン / farnesol / stellettamides / denolimerization / ミカロライド / 内皮 / 毒素 / 生理活性物質 / 海洋生物 / NO / 肥満細胞 / conotoxin / xestospongins / 心筋 / 生理活性 / 海産毒 / macrolide / enzyme inhibitor / echinoderm embryo / alkaloid / bioactive compound / カソクリン / 海洋天然物質 / マイカロライド / 孵化酵素 / アクチン脱重合 / 水圈無脊椎動物 / 動物細胞 / 酵素阻止 / リン酸化 / ヒトデ胚 / ホヤ / 水圏無脊椎動物 / マクロリド / アルカロイド / 棘皮動物胚 / 酵素阻害物質 / Pore-forming / beta-helix / Conformation / Absolute configuration / Unusual amino acids / Marine sponge / Polypeptides / FAB-MS / 2次元NMR / アミノ酸分析 / Theonella swinhoei / 立体 / 二次元NMR / チャンネル形成 / β-ヘリックス / コンフォメーション / 絶対立体配置 / 異常アミノ酸 / Marine Sponges / Serine Proteases / Trypsin / Thrombin / Protease Inhibitors / Marine Invertebrates / テトラペプチド / nazumomide A / セリンプロテア-ゼ / 硫酸コステル / toxadocial A / 海綿動物 / トリプシン / トロンビン / 分子設計 / 天然物ケミカルバイオロジー / 国際研究者交流（韓国） / 国際研究者交流（中国） / 国際研究者交流（米国） / 異分野融合 / 国際交流（スウェーデン） / 国際交流（韓国） / 国際交流（米国） / 国際交流（ドイツ） / 天然物リガンド / 標的同定 / 天然物 / (E)-4-hydroxy-3-methylbut-2-eneyl 1-diphosphate reductase / プレスクアレンニリン酸 / メチルエリスリトールリン酸 / Botryococcene / プレスクアレン二リン酸 / スクアレン / 代替石油生産 / Caチャネル / Vitamin E / プレニル化 / 阻害剤 / MT1-MMP / 血管新生 / Theonella Less

Studies on the mechanism for colony formation by the hydrocarbon producing green microalga Botryococcus braunii
- Principal Investigator
  
  Okada Shigeru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 40040:Aquatic life science-related
- Research Institution
  The University of Tokyo
Search for lead compounds for the Parkinson's disease from untapped sponge resourcesPrincipal Investigator
- Principal Investigator
  
  松永茂樹
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Aquatic life science
- Research Institution
  The University of Tokyo
Analysis of chemical communication between sponge and its symbionts and attempts to cultivate productive symbiontsPrincipal Investigator
- Principal Investigator
  
  Matsunaga Shigeki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Frontiers in Chemical Communications
- Principal Investigator
  
  Kakeya Hideaki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Identification of biosynthetic gene clusters of bioactive natural products and their producing bacteria based on sponges life cycle
- Principal Investigator
  
  Takada Kentaro
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Aquatic life science
- Research Institution
  Kitasato University
  The University of Tokyo
Efficient search for cell cycle inhibitors from marine organisms by usinf Fucci cellsPrincipal Investigator
- Principal Investigator
  
  Matsunaga Shigeki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Aquatic life science
- Research Institution
  The University of Tokyo
Studies on biosynthesis of linear hydrocarbons by microalgae from the viewpoint of biofuel productions
- Principal Investigator
  
  Okada Shigeru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Aquatic life science
- Research Institution
  The University of Tokyo
Search for marine natural products that inhibit the pathway from metabolic syndrome to cadiovascular diseasesPrincipal Investigator
- Principal Investigator
  
  Matsunaga Shigeki
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Aquatic life science
- Research Institution
  The University of Tokyo
培養細胞試験系を用いた抗腫瘍性海洋天然物の探索Principal Investigator
- Principal Investigator
  
  松永茂樹
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Fisheries chemistry
- Research Institution
  The University of Tokyo
Chemical biology using natural products
- Principal Investigator
  
  UEDA Minoru
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
Antitumor ligands from marine organismsPrincipal Investigator
- Principal Investigator
  
  Matsunaga Shigeki
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Search for anti-malaria agents from marine organismsPrincipal Investigator
- Principal Investigator
  
  MATSUNAGA Shigeki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Fisheries chemistry
- Research Institution
  The University of Tokyo
Studies on the mechanisms for biosynthesis of useful hydrocarbons by a green microalga based on data from EST analyses.
- Principal Investigator
  
  OKADA Shigeru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  The University of Tokyo
Search for antitumor marine natural products through growth recovery assay in engineered yeastsPrincipal Investigator
- Principal Investigator
  
  MATSUNAGA Shigeki
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Fisheries chemistry
- Research Institution
  The University of Tokyo
海綿由来の細胞毒性ペプチドをモデルとしたイオンチャネル分子の創製Principal Investigator
- Principal Investigator
  
  松永茂樹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Fisheries chemistry
- Research Institution
  The University of Tokyo
海洋無脊椎動物からのガン関連酵素を標的とする機能分子の探索Principal Investigator
- Principal Investigator
  
  松永茂樹
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Search for compounds active, against fish diseases from marine invertebratesPrincipal Investigator
- Principal Investigator
  
  MATSUNAGA Shigeki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  The University of Tokyo
海洋天然物からの蛋白質プレニル化の阻害剤と内因性修飾物質の探索
- Principal Investigator
  
  KARAKI Hideaki
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokyo
Efficient Utilization of Fisheries Biproducts. Exploration of miomedial Resoures from Deep-Sea Spong
- Principal Investigator
  
  FUSETANI Nobuhiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  The University of Tokyo
Clarification of new cell signaling mediated by intermediairy metabolite of claolesterol
- Principal Investigator
  
  OZAKI Hiroshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  The University of Tokyo
海綿動物由来のヒストンデアセチラーゼ阻害物質の単離と構造研究Principal Investigator
- Principal Investigator
  
  松永茂樹
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
異常アミノ酸を含むペプチドの微量構造解析Principal Investigator
- Principal Investigator
  
  松永茂樹
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
海洋無脊椎動物からの血管新生阻害剤の探索
- Principal Investigator
  
  NAKAO Yoichi
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Development and application of nanotubes based on polytheonamidesPrincipal Investigator
- Principal Investigator
  
  MATSUNAGA Shigeki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  The University of Tokyo
Development of Biochemical Reagents to Study Signal Transduction from Awuatic Organisms
- Principal Investigator
  
  FUSETANI Nobuhiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Fisheries chemistry
- Research Institution
  THE UNIVERSITY OF TOKYO
Actin depolymerize agents isolated from marine organism
- Principal Investigator
  
  KARAKI Hideaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  THE UNIVERSITY OF TOKYO
Studies on novel marine bioactive substances as pharmacological resources
- Principal Investigator
  
  OZAKI Hiroshi
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  The University of Tokyo
Discovery of Highly Selective Antifungal Agents from Marine InvertebratesPrincipal Investigator
- Principal Investigator
  
  MATSUNAGA Shigeki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  The University of Tokyo
海綿Mycale sp.におけるmycalolide類の真の生産生物の特定および培養Principal Investigator
- Principal Investigator
  
  松永茂樹
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Fisheries chemistry
- Research Institution
  The University of Tokyo
SEARCH FOR METABOLITES INFLUENCING CELLAR FUNCTION FROM AQUATIC INVERTEBRATES AND ANLYSIS OF THEIR MODES OF ACTION.
- Principal Investigator
  
  FUSETANI Nobuhiro
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Fisheries chemistry
- Research Institution
  THE UNIVERSITY OF TOKYO
Search for the inhibitors of the glycosidases from marine invertebratesPrincipal Investigator
- Principal Investigator
  
  MATSUNAGA Shigeki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  The University of Tokyo
海綿由来の超異常ペプチドpolytheonamide類の活性発現機序Principal Investigator
- Principal Investigator
  
  松永茂樹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
海綿由来の超異常ポリペプチドpolytheonamide類の活性発現機序
- Principal Investigator
  
  FUSETANI Nobuhiro
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
The structure and activities of theostatins A-C,highly cytotoxic polypeptides from the marine sponge Theonella swinhoei.
- Principal Investigator
  
  FUSETANI Nobuhiro
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  The University of Tokyo
Search for serine protease inhibitors from marine invertebrates.
- Principal Investigator
  
  FUSETANI Nobuhiro
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  University of Tokyo

[Journal Article] Myrindole A, an Antimicrobial Bis-indole from a Marine Sponge Myrmekioderma sp.2021
- Author(s)
  Moosmann Philipp、Taniguchi Tohru、Furihata Kazuo、Utsumi Hiroaki、Ise Yuji、Morii Yasuhiro、Yamawaki Nobuhiro、Takatani Tomohiro、Arakawa Osamu、Okada Shigeru、Matsunaga Shigeki
- Journal Title
  
  Organic Letters
  
  Volume: 9 Issue: 9 Pages: 3477-3480
- DOI
  10.1021/acs.orglett.1c00922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18F18776, KAKENHI-PROJECT-18H02093, KAKENHI-PLANNED-17H06403
[Journal Article] Structure Elucidation of Calyxoside B, a Bipolar Sphingolipid from a Marine Sponge Cladocroce sp. through the Use of Beckmann Rearrangement2021
- Author(s)
  Sugawara Kenji、Watarai Hiroshi、Ise Yuji、Yokose Hisayoshi、Morii Yasuhiro、Yamawaki Nobuhiro、Okada Shigeru、Matsunaga Shigeki
- Journal Title
  
  Marine Drugs
  
  Volume: 19 Issue: 6 Pages: 287-287
- DOI
  10.3390/md19060287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21522, KAKENHI-PLANNED-17H06403
[Journal Article] Deep-Sea Marine Sponge: Application of Asymmetric Dihydroxylation in Structure Elucidation2021
- Author(s)
  1)Kanki, D., Imai, K., Ise, Y., Okada, S., Matsunaga, S.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 84 Issue: 5 Pages: 1676-1680
- DOI
  10.1021/acs.jnatprod.1c00320
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06403
[Journal Article] Homophymamide A, Heterodetic Cyclic Tetrapeptide from a Homophymia sp. Marine Sponge: A Cautionary Note on Configurational Assignment of Peptides That Contain a Ureido Linkage2021
- Author(s)
  Kanki D, Nakamukai S, Ogura Y, Takikawa H, Ise Y, Morii Y, Yamawaki N, Takatani T, Arakawa O, Okada S, Matsunaga S
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 84 Issue: 6 Pages: 1848-1853
- DOI
  10.1021/acs.jnatprod.1c00336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20J13853, KAKENHI-PLANNED-17H06403
[Journal Article] Metachromins X and Y from a marine sponge Spongia sp. and their effects on cell cycle progression.2020
- Author(s)
  Hitora Y, Takada K, Ise Y, Woo S.P, Inoue S, Mori N, Takikawa H, Nakamukai S, Okada S, Matsunaga S
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 28 Issue: 2 Pages: 115233-115233
- DOI
  10.1016/j.bmc.2019.115233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04980, KAKENHI-PLANNED-17H06403
[Journal Article] Heptavalinamide A, an Extensively N-Methylated Linear Nonapeptide from a Cyanobacterium Symploca sp. and Development of a Highly Sensitive Analysis of N,N-Dimethylvaline by LCMS2020
- Author(s)
  Suo R, Watanabe, R, Takada, K, Suzuki T, Oikawa H, Itoi S, Sugita H, Matsunaga S
- Journal Title
  
  Org. Lett.
  
  Volume: 22 Issue: 4 Pages: 1254-1258
- DOI
  10.1021/acs.orglett.9b04420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04980, KAKENHI-PLANNED-17H06403
[Journal Article] Microsclerodermins N and O, cytotoxic cyclic peptides containing a p-ethoxyphenyl moiety from a deep-sea marine sponge Pachastrella sp.2020
- Author(s)
  Tian T, Takada K, Ise. Y, Ohtsuka S, Okada S, Matsunaga S
- Journal Title
  
  Tetrahedron
  
  Volume: 76 Issue: 10 Pages: 130997-130997
- DOI
  10.1016/j.tet.2020.130997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04980, KAKENHI-PLANNED-17H06403
[Journal Article] Isolation and identification of N6-isopentenyladenosine as the cytotoxic constituent of a marine sponge Oceanapia sp.2019
- Author(s)
  Nakamukai Shohei、Ise Yuji、Ohtsuka Susumu、Okada Shigeru、Matsunaga Shigeki
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 83 Issue: 11 Pages: 1985-1988
- DOI
  10.1080/09168451.2019.1630258
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06403
[Journal Article] Poecillastrin H, a Chondropsin-type Macrolide with a Conjugated Pentaene Moiety, from a Characella sp. Marine Sponge2018
- Author(s)
  Rei Suo, Kentaro Takada, Raku Irie, Ryuichi Watanabe, Toshiyuki Suzuki, Yuji Ise, Susumu Ohtsuka, Shigeru Okada, and Shigeki Matsunaga
- Journal Title
  
  Journal of Natural Products
  
  Volume: 81(5) Issue: 5 Pages: 1295-1299
- DOI
  10.1021/acs.jnatprod.8b00180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16J07837, KAKENHI-PROJECT-17J08775, KAKENHI-PROJECT-16H04980, KAKENHI-PLANNED-17H06403
[Journal Article] Lactomycins A-C, Dephosphorylated Phoslactomycin Derivatives that Inhibit Cathepsin B, from the Marine-derived Streptomyces sp. ACT2322018
- Author(s)
  Yi Sun, Rogie Royce Carandang, Yuta Harada, Shigeru Okada, Kazutoshi Yoshitake, Shuichi Asakawa, Yuichi Nogi, Shigeki Matsunaga, Kentaro Takada
- Journal Title
  
  Mar. Drugs
  
  Volume: 16 Issue: 2 Pages: 70-70
- DOI
  10.3390/md16020070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06403, KAKENHI-PROJECT-16H04980
[Journal Article] Stellatolide H, a cytotoxic peptide lactone from a deep-sea sponge Discodermia sp.2018
- Author(s)
  Nakamukai Shohei、Takada Kentaro、Furihata Kazuo、Ise Yuji、Okada Shigeru、Morii Yasuhiro、Yamawaki Nobuhiro、Takatani Tomohiro、Arakawa Osamu、Gustafson Kirk R.、Matsunaga Shigeki
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 59 Issue: 26 Pages: 2532-2536
- DOI
  10.1016/j.tetlet.2018.05.033
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19238, KAKENHI-PROJECT-15H04552, KAKENHI-PROJECT-16H04980, KAKENHI-PLANNED-17H06403
[Journal Article] 2.Fukuhara, K., Takada, K.*, Watanabe, R., Suzuki, T., Okada, S., Matsunaga, S.* Colony-wise Analysis of a Theonella swinhoei Marine Sponge with a Yellow Interior Permitted the Isolation of Theonellamide I.2018
- Author(s)
  2.Fukuhara, K., Takada, K.*, Watanabe, R., Suzuki, T., Okada, S., Matsunaga, S.*
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 81 Issue: 11 Pages: 2595-2599
- DOI
  10.1021/acs.jnatprod.8b00591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04980, KAKENHI-PLANNED-17H06403
[Journal Article] Miuramides A and B, Trisoxazole Macrolides from a Mycale sp. Marine Sponge, That Induce a Protrusion Phenotype in Cultured Mammalian Cells2018
- Author(s)
  Rei Suo, Kentaro Takada, Hisanori Kohtsuka, Yuji Ise, Shigeru Okada, and Shigeki Matsunaga
- Journal Title
  
  Journal of Natural Products
  
  Volume: 81(4) Issue: 4 Pages: 1108-1112
- DOI
  10.1021/acs.jnatprod.8b00101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16J07837, KAKENHI-PROJECT-16H04980, KAKENHI-PLANNED-17H06403
[Journal Article] Poecillastrin E, F, and G, cytotoxic chondropsin-type macrolides from a marine sponge Poecillastra sp.2018
- Author(s)
  Raku Irie, Yuki Hitora, Yuji Ise, Shigeru Okada, Kentaro Takada, Shigeki Matsunaga
- Journal Title
  
  Tetrahedron
  
  Volume: 74 Issue: 13 Pages: 1430-1434
- DOI
  10.1016/j.tet.2018.01.037
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06403, KAKENHI-PROJECT-16H04980, KAKENHI-PROJECT-17J08775, KAKENHI-PROJECT-15K18594
[Journal Article] Resolution of the Confusion in the Assignments of Configuration for the Ciliatamides, Acylated Dipeptides2017
- Author(s)
  Kentaro Takada, Raku Irie, Rei Suo, Shigeki Matsunaga
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 80 Issue: 10 Pages: 2845-2849
- DOI
  10.1021/acs.jnatprod.7b00684
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06403, KAKENHI-PROJECT-16H04980
[Journal Article] Structure Revision of Poecillastrin C and the Absolute Configuration of the β-Hydroxyaspartic Acid Residue2017
- Author(s)
  Raku Irie, Kentaro Takada, Yuji Ise, Susumu Ohtsuka, Shigeru Okada, Kirk R. Gustafson, Shigeki Matsunaga
- Journal Title
  
  Org. Lett.
  
  Volume: 19 Issue: 19 Pages: 5395-5397
- DOI
  10.1021/acs.orglett.7b02835
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06403, KAKENHI-PROJECT-16H04980, KAKENHI-PROJECT-17J08775, KAKENHI-PROJECT-15K18594
[Journal Article] Yakushinamides, polyoxygenated fatty acid amides that inhibit HDACs and SIRTs, from the marine sponge Theonella swinhoei.2016
- Author(s)
  Takada K, Imae Y, Ise Y, Ohtsuka S, Ito A, Okada S, Yoshida M, Matsunaga S.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 79 Issue: 9 Pages: 2384-2390
- DOI
  10.1021/acs.jnatprod.6b00588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-16H04980, KAKENHI-PROJECT-15K18594
[Journal Article] Curacin E from the Brittle Star Ophiocoma scolopendrina2016
- Author(s)
  Ueoka, R.; Hitora, U.; Ito, A.; Yoshida, M.; Okada, S.; Takada, K.; Matsunaga, S.
- Journal Title
  
  Journal of Natural Products
  
  Volume: 79 Issue: 10 Pages: 2754-2757
- DOI
  10.1021/acs.jnatprod.6b00701
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25252037, KAKENHI-PROJECT-16H04980, KAKENHI-PROJECT-15K14799
[Journal Article] Dragmacidins G and H, Bisindole Alkaloids Tethered by a Guanidino Ethylthiopyrazine Moiety, from a Lipastrotethya sp. Marine Sponge2016
- Author(s)
  Hitora, H.; Takada, K.; Ise, Y.; Okada, S.; Matsunaga, S.
- Journal Title
  
  Journal of Natural Products
  
  Volume: 79 Issue: 11 Pages: 2973-2976
- DOI
  10.1021/acs.jnatprod.6b00710
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25252037, KAKENHI-PROJECT-16H04980, KAKENHI-PROJECT-15J09122, KAKENHI-PROJECT-15K14799, KAKENHI-PROJECT-15K18594
[Journal Article] Biosynthetic gene cluster for surugamide A encompasses an unrelated decapeptide, surugamide F2016
- Author(s)
  Ninomiya, A., Katsuyama, Y., Kuranaga, T., Miyazaki, M., Nogi, Y., Okada, S., Wakimoto, T., Ohnishi, Y., Matsunaga, S., Takada, K.
- Journal Title
  
  ChemBioChem
  
  Volume: 17 Issue: 18 Pages: 1709-1712
- DOI
  10.1002/cbic.201600350
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-16H06448, KAKENHI-PROJECT-15H03112, KAKENHI-PROJECT-16H04980, KAKENHI-PROJECT-15K12740
[Journal Article] Nazumazoles A-C, Cyclic Pentapeptides Dimerized through a Disulfide Bond from the Marine Sponge Theonella swinhoei.2015
- Author(s)
  Fukuhara, K.; Takada, K.; Okada, S.; Matsunaga, S.
- Journal Title
  
  Org. Lett.
  
  Volume: 17 Issue: 11 Pages: 2646-2648
- DOI
  10.1021/acs.orglett.5b01020
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23102007, KAKENHI-PROJECT-25712024
[Journal Article] Two Cell Differentiation Inducing Pyridoacridines from a Marine Sponge Biemna sp. and Their Chemical Conversions2015
- Author(s)
  Moran, D.A.P., Takada, K., Ise, Y., Bontemps, N., Rohan, D., Furihata, K., Okada, S. and Matsunaga, S.
- Journal Title
  
  Tetrahedron
  
  Volume: 71 Issue: 30 Pages: 5013-5018
- DOI
  10.1016/j.tet.2015.05.070
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18594, KAKENHI-PLANNED-23102007, KAKENHI-PROJECT-25712024
[Journal Article] Cytotoxic Glycosylated Fatty Acid Amides from a Stelletta sp. Marine Sponge2015
- Author(s)
  V. Peddie, K. Takada, S. Okuda, Y. Ise, Y. Morii, N. Yamawaki, T. Takatani, O. Arakawa,⊥ S. Okada, and S. Matsunaga
- Journal Title
  
  Journal of Natural Products
  
  Volume: 78 Issue: 11 Pages: 2808-2813
- DOI
  10.1021/acs.jnatprod.5b00795
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450287, KAKENHI-PROJECT-15K18594, KAKENHI-PLANNED-23102007, KAKENHI-PROJECT-25712024
[Journal Article] Cytotoxic linear acetylenes from a marine sponge Pleroma sp.2015
- Author(s)
  Takahashi, E., Takada, K., Hashimoto, M., Itoh, Y., Ise, Y., Otsuka, S., Okada, S. and Matsunaga, S.
- Journal Title
  
  Tetrahedron
  
  Volume: 71 Issue: 51 Pages: 9564-9570
- DOI
  10.1016/j.tet.2015.10.062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18594, KAKENHI-PLANNED-23102007, KAKENHI-PROJECT-25712024
[Journal Article] Structural reappraisal of corticatic acids, biologically active linear polyacetylenes, from a marine sponge of the genus Petrosia2014
- Author(s)
  K. Takada, S. Okada, S. Matsunaga
- Journal Title
  
  Fish. Sci.
  
  Volume: 80 Issue: 5 Pages: 1057-1064
- DOI
  10.1007/s12562-014-0776-0
- NAID
  40020207530
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23102007, KAKENHI-PROJECT-25660163, KAKENHI-PROJECT-25712024
[Journal Article] Lower Homologues of Ahpatinin, Aspartic Protease Inhibitors, from a Marine Streptomyces sp.2014
- Author(s)
  Y. Sun, K. Takada, Y. Nogi, S. Okada, S. Matsunaga
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 77 Issue: 7 Pages: 1749-1752
- DOI
  10.1021/np500337m
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23102007, KAKENHI-PROJECT-25660163, KAKENHI-PROJECT-25712024
[Journal Article] Stimulators of adiponenesis from the marine sponge Xestospongia testudinaria2013
- Author(s)
  Akiyama, T.; Takada, K.; Oikawa, T.; Matsuura, N.; Ise, Y.; Okada, S.; Matsunaga, S.
- Journal Title
  
  Tetrahedron
  
  Volume: 69 Issue: 32 Pages: 6560-6564
- DOI
  10.1016/j.tet.2013.06.007
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23102007, KAKENHI-PROJECT-25252037, KAKENHI-PROJECT-25660163, KAKENHI-PROJECT-25712024
[Journal Article] Surugamides, Cyclic Octapeptides with Four D-Amino Acid Residues, from a Marine Streptomyces sp.: LCMS-Aided Inspection of Partial Hydrolysates for the Distinction of D- and L-Amino Acid Residues in the Sequence2013
- Author(s)
  Takada, K.; Ninomiya A.; Naruse, M.; Sun, Y.; Miyazaki, M.; Nogi, Y.; Okada, S. Matsunaga, S.
- Journal Title
  
  J. Org. Chem.
  
  Volume: 78 Issue: 13 Pages: 6746-6750
- DOI
  10.1021/jo400708u
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23102007, KAKENHI-PROJECT-25660163, KAKENHI-PROJECT-25712024
[Journal Article] On the Assignment of the Absolute Configuration at the Isolated Methyl Branch in Miyakosyne A, Cytotoxic Linear Acetylene, from the Deep-Sea Marine Sponge Petrosia sp.2013
- Author(s)
  Hitora, Y.; Takada, K.; Matsunaga, S.
- Journal Title
  
  Tetrahedron
  
  Volume: 69 Issue: 52 Pages: 11070-11073
- DOI
  10.1016/j.tet.2013.11.013
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23102007, KAKENHI-PROJECT-25660163, KAKENHI-PROJECT-25712024
[Journal Article] The single cellular green microalga Botryococcus braunii, race B possesses three distinct 1-deoxy-D-xylulose 5-phosphate synthases2012
- Author(s)
  D. Matsushima、H. Jenke-Kodama、Y. Sato、Y. Fukunaga、K. Sumimoto、T. Kuzuyama、S. Matsunaga、S. Okada
- Journal Title
  
  Plant Sci.
  
  Volume: 185-186 Pages: 309-320
- DOI
  10.1016/j.plantsci.2012.01.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380130
[Journal Article] Novel Bromotyrosine Derivatives That Inhibit Growth of the Fish Pathogenic Bacterium Aeromonas hydrophila, from a Marine Sponge Hexadella sp.2005
- Author(s)
  Matsunaga et al.
- Journal Title
  
  J.Org.Chem. 70-5
  
  Pages: 1893-1896
- Data Source
  KAKENHI-PROJECT-16380142
[Journal Article] Novel bromotyrosine derivatives that inhibit growth of the fish pathogenic bacterium Aeromonas hydrophila, from a marine sponge Hexadella sp.2005
- Author(s)
  Matsunaga, S.
- Journal Title
  
  Journal of Organic Chemistry 70
  
  Pages: 1893-1896
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380142
[Journal Article] Novel bromotyrosine derivatives that inhibit growth of the fish pathogenic bacterium Aeromonas hydrophila, from a marine sponge Hexadella sp.2005
- Author(s)
  S.Matsunaga
- Journal Title
  
  Journal of Organic Chemistry 70卷
  
  Pages: 1893-1896
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380142
[Journal Article] Tetradehydrohalicyclamine A and 22-Hydroxyhalicyclamine A, New Cytotoxic Bis-piperidine Alkaloids from a Marine Sponge Amphimedon2004
- Author(s)
  Matsunaga et al.
- Journal Title
  
  J.Nat.Prod. 67-10
  
  Pages: 1758-1760
- Data Source
  KAKENHI-PROJECT-16073207
[Presentation] 微細緑藻Botryococcus braunii S品種はlycopaoctaeneを生産するＬ品種である2022
- Author(s)
  上杉一馬、Holger Jenke-Kodama、松永茂樹、岡田　茂、河村耕史
- Organizer
  令和4年度日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-19H03043
[Presentation] ゴン曽根産未同定種カイメン由来新規スフィンゴ糖脂質の単離と構造決定2021
- Author(s)
  菅原憲二・岡田茂・松永茂樹
- Organizer
  日本水産学会春季大会
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] サンゴ曽根産Neopeltidae科カイメン由来新規ペプチドの単離および構造決定2021
- Author(s)
  神吉大地・中迎菖平・岡田茂・松永茂樹
- Organizer
  日本水産学会春季大会
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] 大島新曽根産Luffariella属カイメン由来新規テルペン類の単離および構造決定2021
- Author(s)
  神吉大地・今井健・岡田茂・松永茂樹
- Organizer
  日本水産学会春季大会
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] 生物活性海洋天然物の単離・構造決定2021
- Author(s)
  松永茂樹
- Organizer
  第23回天然薬物の開発と応用シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] 微細緑藻Botryococcus braunii S品種はS品種特異的な炭化水素を作らない2021
- Author(s)
  上杉一馬、松永茂樹、岡田　茂、河村耕史
- Organizer
  令和３年度日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-19H03043
[Presentation] 大島新曽根産カイメンからのノルトプセンチンＢダイマーの単離および構造決定2020
- Author(s)
  中迎菖平、岡田茂、松永茂樹
- Organizer
  令和2年度日本水産学会春季大会
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] 微細緑藻Botryococcus braunii S品種の炭化水素分析2020
- Author(s)
  上杉一馬，松永茂樹，岡田　茂，河村耕史
- Organizer
  令和2年度日本水産学会春季大会
- Data Source
  KAKENHI-PROJECT-19H03043
[Presentation] 未同定種カイメンから単離した新規環状ペプチドの単離と構造2020
- Author(s)
  神吉大地、中迎菖平、岡田茂、松永茂樹
- Organizer
  令和2年度日本水産学会春季大会
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] Microsclerodermins N-P from deep-sea marine sponges2020
- Author(s)
  Tian, T., Takada, K., Okada, S., Matsunaga, S.
- Organizer
  令和2年度日本水産学会春季大会
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] 石垣島川平湾産のシアノバクテリアから見出した新規ペプチドの単離と構造決定2019
- Author(s)
  周防玲、高田健太郎、岡田茂、松永茂樹
- Organizer
  平成31年度日本水産学会春季大会
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] 大島新曽根産カイメンからのイソペンテニルアデノシンの単離2019
- Author(s)
  中迎菖平・岡田茂、松永茂樹
- Organizer
  平成31年度日本水産学会春季大会
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] Two cytotoxic cyclic peptides from an unidentified marine sponge2019
- Author(s)
  田添、高田健太郎、岡田茂、松永茂樹
- Organizer
  平成31年度日本水産学会春季大会
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] カイメンの二次代謝産物生産を可能にする化学コミュニケーション2019
- Author(s)
  松永茂樹、高田健太郎、藤田雅紀
- Organizer
  日本化学会第99春季年会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] Biologically active sponge metabolites isolated through cell-based assays2019
- Author(s)
  Matsunaga, S.
- Organizer
  12th International Marine Biotechnology Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] カイメン由来の細胞毒性マクロライドpoecillastrin類の構造訂正2018
- Author(s)
  入江樂、高田健太郎、岡田茂、松永茂樹、伊勢優史、大塚攻、Kirk R. Gustafson
- Organizer
  平成30年度日本水産学会春季大会
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] Biologically active marine metabolites isolated through cell-based assays2018
- Author(s)
  Shigeki Matsunaga
- Organizer
  Fifty Years of Marine Natural Products, Ecology and Drug Development
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] Discovery and structure revision of biologically active marine natural products2018
- Author(s)
  Shigeki Matsunaga
- Organizer
  2018 International symposium on marine natural products
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] 細胞の形態変化を指標とした大要天然物の探索2018
- Author(s)
  周防玲、高田健太郎、幸塚久典、伊勢優史、入江樂、渡邊龍一、鈴木敏之、大塚攻、岡田茂、松永茂樹
- Organizer
  第60回天然有機化合物討論会
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] Poecillastra属カイメン由来新規poecillastrin 類縁体の単離と構造決定2018
- Author(s)
  周防玲、高田健太郎、入江　樂、渡邊龍一、鈴木敏之、大塚攻、岡田茂、松永茂樹
- Organizer
  平成30年度日本水産学会春季大会
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] Cell-based assay によって Mycale属カイメンから見出したmiuramide 類の単離と構造決定2018
- Author(s)
  周防玲、高田健太郎、岡田茂、幸塚久典、松永茂樹
- Organizer
  平成30年度日本水産学会春季大会
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] 細胞毒性ビスインドールアルカロイドdragmacidin GおよびHの単離と構造決定2017
- Author(s)
  人羅勇気、高田健太郎、岡田茂、松永茂樹、伊勢優史
- Organizer
  平成２９年度日本水産学会春季大会
- Place of Presentation
  東京海洋大学（東京都）
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-15K14799
[Presentation] カイメン由来の抗腫瘍性物質poecillastrin 類の構造研究2017
- Author(s)
  入江樂，人羅勇気，高田健太郎，岡田茂，松永茂樹
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] Structure investigation of poecillastrins2017
- Author(s)
  Raku Irie, Kentaro Takada, Shigeru Okada, Shigeki Matsunaga
- Organizer
  International symposium "Fisheries science for future generation"
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] Discovery and chemistry of biologically active marine natural products2017
- Author(s)
  Shigeki Matsunaga, Kentaro Takada, Yuki Hitora, Reiko Ueoka, Shigeru Okada, Yuji Ise
- Organizer
  International symposium "Fisheries science for future generation"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] Theonellamide H, a “Colony Dependent” Cytotoxic Peptide from the Marine Sponge Theonella swinhoei2017
- Author(s)
  Kazuya Fukuhara, Kentaro Takada, Shigeru Okada, Shigeki Matsunaga
- Organizer
  International symposium "Fisheries science for future generation"
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] 生物活性海洋天然物の探索：単離、構造決定、構造訂正2017
- Author(s)
  松永茂樹
- Organizer
  第10回北里化学シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] カイメンTheonella swinhoei 由来の分布に個体差のあるtheonellamide 類縁体の単離と構造決定2017
- Author(s)
  福原和哉，高田健太郎，岡田茂，松永茂樹
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] 石垣島川平産ウデフリクモヒトデ由来の細胞毒性物質2017
- Author(s)
  上岡麗子、人羅勇気、岡田茂、高田健太郎、松永茂樹、伊藤昭博、吉田稔
- Organizer
  平成２９年度日本水産学会春季大会
- Place of Presentation
  東京海洋大学（東京都）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K14799
[Presentation] Mycale 属カイメンからの新規mycalolide 類縁体の単離と構造決定2017
- Author(s)
  周防玲，高田健太郎，岡田茂，幸塚久典，松永茂樹
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] Isolation and actin assisted structure conversion of a trisoxazole macrolide2017
- Author(s)
  Rei Suo, Kentaro Takada, Shigeru Okada, Shigeki Matsunaga
- Organizer
  International symposium "Fisheries science for future generation"
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06403
[Presentation] Structure elucidation of sponge metabolites with anti-tumor associated activities2014
- Author(s)
  Kentaro Takada, Yasufumi Imae, Emi Takanashi, and Shigeki Matsunaga
- Organizer
  4th Juior International Conference on Cutting-Edge Organic Chemistry in Asia
- Place of Presentation
  Bangkok. Thailan
- Year and Date
  2014-11-29
- Invited
- Data Source
  KAKENHI-PLANNED-23102007
[Presentation] Streptomyces属放線菌が生産するsurugamide類の生合成と機能に関する研究2014
- Author(s)
  二宮章洋、松永茂樹、その他
- Organizer
  平成２６年度日本水産学会春季大会
- Place of Presentation
  北海道大学水産学部
- Data Source
  KAKENHI-PLANNED-23102007
[Presentation] カイメン由来細胞毒性アセチレン化合物miyakosyne Aの遠隔位不斉中心の絶対配置の決定2014
- Author(s)
  人羅勇気、松永茂樹、その他
- Organizer
  平成２６年度日本水産学会春季大会
- Place of Presentation
  北海道大学水産学部
- Data Source
  KAKENHI-PLANNED-23102007
[Presentation] カイメンTheonella swinhoei由来の新規ペプチドの単離と構造決定2014
- Author(s)
  福原和哉、松永茂樹、その他
- Organizer
  平成２６年度日本水産学会春季大会
- Place of Presentation
  北海道大学水産学部
- Data Source
  KAKENHI-PLANNED-23102007
[Presentation] 屋久新曽根産カイメンTheonella sp.由来の新規HDAC1阻害物質の単離と構造決定2014
- Author(s)
  高田健太郎、松永茂樹、その他
- Organizer
  平成２６年度日本水産学会春季大会
- Place of Presentation
  北海道大学水産学部
- Data Source
  KAKENHI-PLANNED-23102007
[Presentation] Cell differentiation inducers isolated from a marine sponge2014
- Author(s)
  Daniel Pedrazzoli、松永茂樹、その他
- Organizer
  平成２６年度日本水産学会春季大会
- Place of Presentation
  北海道大学水産学部
- Data Source
  KAKENHI-PLANNED-23102007
[Presentation] 海洋生物由来の生物活性物質：探索・単離・構造決定2014
- Author(s)
  松永茂樹
- Organizer
  第49回天然物化学談話会
- Place of Presentation
  倉敷市
- Year and Date
  2014-07-04
- Invited
- Data Source
  KAKENHI-PLANNED-23102007
[Presentation] 屋久新曽根産カイメンTheonella sp.由来の新規HDAC1阻害物質の単離と構造決定2013
- Author(s)
  今榮康文、松永茂樹、その他
- Organizer
  第55回天然有機化合物討論会
- Place of Presentation
  同志社大学寒梅館
- Data Source
  KAKENHI-PLANNED-23102007
[Presentation] Marine natural products with anti-cancer related activities2013
- Author(s)
  Shigeki Matsunaga, Kentaro Takada, Yuki Hitora, Akihiro Ninomiya, Yasufumi Imae, Yi Sun, Masato Naruse, Emi Takanashi
- Organizer
  XIV International Symposium on Marine Natural Products
- Place of Presentation
  La Toja, Spain
- Invited
- Data Source
  KAKENHI-PLANNED-23102007
[Presentation] Marine Natural Products with Anti-cancer Related Activities2013
- Author(s)
  Shigeki Matsunaga,* Kentaro Takada, Yuki Hitora, Akihiro Ninomiya, Yasufumi Imae, Yi Sun, Masato Naruse, Emi Takanashi, Masashi Suzuki
- Organizer
  13th Intgernational Conference on the Chemistry of Antibiotics and Other Bioactive Compounds
- Place of Presentation
  山梨県南都留郡
- Invited
- Data Source
  KAKENHI-PLANNED-23102007
[Presentation] Biologically active metabolites from sponges and microbes2012
- Author(s)
  Shigeki Matsunaga
- Organizer
  The 9th Asia-Pacific Marine Biotechnology Conference
- Place of Presentation
  高知市文化プラザ
- Invited
- Data Source
  KAKENHI-PLANNED-23102007
[Presentation] Bioactive ligands from marine organisms2012
- Author(s)
  Shigeki Matsunaga
- Organizer
  The 7th International conference on cutting-edge organic Chemistry in Asia
- Place of Presentation
  Nanyang Technological University
- Invited
- Data Source
  KAKENHI-PLANNED-23102007
[Presentation] Bioactive ligands from marine organisms2012
- Author(s)
  Shigeki Matsunaga
- Organizer
  2012 International Symposium on Natural Product and Drug Discovery and Pharmaceutical Education
- Place of Presentation
  Sunchon National University, Korea
- Invited
- Data Source
  KAKENHI-PLANNED-23102007
[Presentation] Bioactive ligands from marine organisms2012
- Author(s)
  Shigeki Matsunaga
- Organizer
  The 1st International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity
- Place of Presentation
  京都センチュリーホテル
- Invited
- Data Source
  KAKENHI-PLANNED-23102007
[Presentation] Cloning and characterization of 1-deoxy-D-xylulose 5-phosphate reductoisomerase from the B race of a green microalga Botryococcus braunii2011
- Author(s)
  K. Fujisawa、H. Jenke-Kodama、T. Kurokawa、Y. Fukunaga、S. Matsunaga、S. Okada
- Organizer
  TERPNET2011
- Place of Presentation
  Kalmar、Sweden
- Year and Date
  2011-05-24
- Data Source
  KAKENHI-PROJECT-21380130
[Presentation] 微細緑藻Botryococcus brauniiのトリテルペン生合成関連遺伝子の発現解析2011
- Author(s)
  福永有佑、岡田茂、松永茂樹、T. Niehaus、J. Chappell
- Organizer
  平成23年度日本水産学会春季大会
- Place of Presentation
  東京
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21380130
[Presentation] 微細藻Botryococous braunij-B品種の4-hydroxy-3-methylbut-2-enyl diphosphate reductase遺伝子の機能・発現解析2010
- Author(s)
  住本惟光・岡田茂・松永茂樹
- Organizer
  平成22年度日本水産学会春季大会
- Place of Presentation
  日本大学生物資源科学部
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21380130
[Presentation] Characterization of 4-hydroxy-3-methylbut-2-enyl diphosphate reductase from the green microalga Botryococcus braunii, race B2009
- Author(s)
  K. Sumimoto、S. Okada、S. Matsunaga
- Organizer
  TERPNET2009
- Place of Presentation
  Tokyo、Japan
- Year and Date
  2009-05-26
- Data Source
  KAKENHI-PROJECT-21380130
[Presentation] Biologically active secondary metabolites from Japanese marine invertebrates2008
- Author(s)
  S. Matsunaga
- Organizer
  CMDD Symposium
- Place of Presentation
  ソウル
- Year and Date
  2008-11-02
- Data Source
  KAKENHI-PROJECT-16073207

1. FUSETANI Nobuhiro (70012010)

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
2. NAKAO Yoichi (60282696)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. OZAKI Hiroshi (30134505)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. KARAKI Hideaki (60011912)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. OKADA Shigeru (00224014)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
6. Takada Kentaro (90455353)

# of Collaborated Projects: 3 results

# of Collaborated Products: 33 results
7. HORI Masatoshi (70211547)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. MURAMATSU Ikunobu (10111965)

# of Collaborated Projects: 2 results

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9. KUZUYAMA Tomohisa (30280952)

# of Collaborated Projects: 2 results

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10. UEDA Minoru (60265931)

# of Collaborated Projects: 2 results

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11. WATABE Shugo (40111489)

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12. 入江一浩 (00168535)

# of Collaborated Projects: 2 results

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13. VICTORIA Peddie

# of Collaborated Projects: 2 results

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14. YOSHIDA Minoru (80191617)

# of Collaborated Projects: 1 results

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15. OTOGURO Kazuhiko (80118794)

# of Collaborated Projects: 1 results

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16. Yoshida Minoru (00182791)

# of Collaborated Projects: 1 results

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17. Nogi Yuichi (70399559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. IKEDA Megumi (90535402)

# of Collaborated Projects: 1 results

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19. IKEGAMI Susumu (80011980)

# of Collaborated Projects: 1 results

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20. NAKAYAMA Hiroyuki (40155891)

# of Collaborated Projects: 1 results

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21. OIKI Shigetoshi (10185176)

# of Collaborated Projects: 1 results

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22. SATO Koichi (90205914)

# of Collaborated Projects: 1 results

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23. OGAWA Kazuo (20092174)

# of Collaborated Projects: 1 results

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24. Kakeya Hideaki (00270596)

# of Collaborated Projects: 1 results

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25. 渡邉秀典 (00202416)

# of Collaborated Projects: 1 results

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26. 品田哲郎 (30271513)

# of Collaborated Projects: 1 results

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27. 小林資正 (40116033)

# of Collaborated Projects: 1 results

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28. 叶直樹 (40317293)

# of Collaborated Projects: 1 results

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29. 岡本隆一 (50451935)

# of Collaborated Projects: 1 results

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30. 井本正哉 (60213253)

# of Collaborated Projects: 1 results

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31. 半田宏 (80107432)

# of Collaborated Projects: 1 results

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32. 渡辺肇 (80212322)

# of Collaborated Projects: 1 results

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33. 佐々木誠 (80235267)

# of Collaborated Projects: 1 results

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34. 木越英夫 (90169839)

# of Collaborated Projects: 1 results

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35. 西川俊夫 (90208158)

# of Collaborated Projects: 1 results

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36. 石橋正己 (90212927)

# of Collaborated Projects: 1 results

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37. 及川勉 (40120141)

# of Collaborated Projects: 1 results

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38. 廣田洋 (00126153)

# of Collaborated Projects: 1 results

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39. 西尾和人 (10208134)

# of Collaborated Projects: 1 results

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40. 村田道雄 (40183652)

# of Collaborated Projects: 1 results

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41. 上杉志成 (10402926)

# of Collaborated Projects: 1 results

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42. 菊地和也 (70292951)

# of Collaborated Projects: 1 results

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43. 榊原康文 (10287427)

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44. BOONE CHARLES (70601342)

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45. 長田裕之 (80160836)

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47. ISHIDA Yukisato

# of Collaborated Projects: 1 results

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48. KAMIMORI Hitoshi

# of Collaborated Projects: 1 results

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49. PEDDIE Victoria

# of Collaborated Projects: 1 results

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50. MOOSMANN PHILIPP

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
51. TAKATANI Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
52. WATARAI Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. WAKIMOTO Toshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 伊勢優史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
55. 荒川修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MATSUNAGA Shigeki 松永 茂樹

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Search for lead compounds for the Parkinson's disease from untapped sponge resourcesPrincipal Investigator

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Analysis of chemical communication between sponge and its symbionts and attempts to cultivate productive symbiontsPrincipal Investigator

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Efficient search for cell cycle inhibitors from marine organisms by usinf Fucci cellsPrincipal Investigator

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Search for marine natural products that inhibit the pathway from metabolic syndrome to cadiovascular diseasesPrincipal Investigator

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培養細胞試験系を用いた抗腫瘍性海洋天然物の探索Principal Investigator

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Antitumor ligands from marine organismsPrincipal Investigator

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Search for anti-malaria agents from marine organismsPrincipal Investigator

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Search for antitumor marine natural products through growth recovery assay in engineered yeastsPrincipal Investigator

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MATSUNAGA Shigeki 松永茂樹