HAYASHI Yoshio 林良夫

… Alternative Names

林良夫ハヤシヨシオ

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Researcher Number	00127854
Other IDs
Affiliation (based on the past Project Information) *help	2011: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 客員教授 2010: 徳島大学, 大学院・ヘルスパイオサイエンス研究部, 教授 2007 – 2010: The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 教授 2006: 徳島大学, 大学院ヘルスバイオサイエンス研究部, 教授 2004 – 2005: The University of Tokushima, Graduate School・Health Bioscience Center, Oral Pathology, Professor, 大学院・ヘルスバイオサイエンス研究部, 教授 … More 2000 – 2003: 徳島大学, 歯学部, 教授 1991 – 1998: 徳島大学, 歯学部, 教授 1989: 徳島大学, 歯学部, 教授 1988: 東京都老人研, 基礎病理部, 研究員 1986: 徳島大学, 歯学部附属病院, 講師 Less
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Pathobiological dentistry/Dental radiology / 病態科学系歯学(含放射線系歯学) / Experimental pathology / Experimental pathology Except Principal Investigator 外科・放射線系歯学 / Orthodontic/Pediatric dentistry / Experimental pathology / 補綴理工系歯学 / Surgical dentistry
Keywords	Principal Investigator シェーグレン症候群 / Sjogren's syndrome / 疾患モデル / NFS / 自己抗原 / Autoantigen / Animal model / Cytokine / α-フォドリン / アポトーシス … More / 自己免疫疾患 / α-fodrin / RT-PCR / シェ-グレン症候群 / 自己免疫 / Therapeutic effect / sldマウス / MRL / Apoptosis / T細胞エピトープ / 自己反応性T細胞 / alpha-fodrin / Synthetic peptide / lprマウス / T細胞レセプター / サイトカイン / salivary gland / autoreactive T cells / autoimmune sialadenitis / 調節性T細胞 / エストロゲン / RbAp48 / カスパーゼ / マウス / 唾液腺 / peptide-based immunotherapy / fusion protein / α-fodrin cDNA / ELISA assay / specific diagnostic system / autoantigen / autoimmune disease / 高感度ELISA / 抗原エピトープ / 特異的治療法 / リコンビナント蛋白 / α-fodrin遺伝子 / ELISA法 / 特異的診断法 / Estrogen-deficiency / AICD / Fas Ligand / Caspase / 膜骨格タンパク / 実験的治療 / deletin mutagenesis法 / 末梢トレランス / アナログペプチド / エストロジェン欠乏 / B cell epitope / T cell epitope / Autoreactive T cells / sld mouse / Sjogren syndrome / Cleavage / Fusion protein / Bcl-2フアミリー / Fas抗原 / B細胞エピトープ / sidマウス / 合成ペプチド治療 / 自己抗原ペプチド / Sjogren′s syndrome / Autommunity / sld mice / lpr mice / T cell receptor / SCIDマウス / 1prマウス / ミュ-タントマウス / 自己免疫性唾液腺炎 / cytokine / Sjogren's syndrome. / 免疫組織化学 / T細胞 / 老化 / 細胞免疫療法 / 細胞移入 / カテプシンL / RNA干渉 / アロマターゼ / CCR7 / 治療法開発 / チトクロムc / p53 / 性差 / 抹消トレランス / IFN-γ / クラスII分子 / Fas / RANKL / トレランス / システインプロテアーゼ / 治療法 / 分子制御 / Fasリガンド / 実験的治療法 / モデル動物 / α-フオドリン / ミュ-タント / 糖鎖構造 / レクチン … More Except Principal Investigator MRL / RANKL / caspase / 樹状細胞 / シェーグレン症候群 / Therapy of Oral cancer / Phenotype of cancer cells / Subsets of peripheral blood lymphocyte / LAK cells / NK cells / Killer lymphocyte / Immune response / Oral cancer / Killer リンパ球 / 単クローン抗体 / リンパ球亜群 / 唾液腺癌細胞 / ADCC / 末梢リンパ球亜群 / Killerリンパ球 / 口腔癌治療 / 癌細胞表現形質 / 抹消リンパ球亜群 / LAK細胞 / NK細胞 / killerリンパ球 / 免疫応答 / 口腔癌 / Osteoclast / Dendritic cell / lpr mice / Bone destruction / Estrogen / Rheumatoid arthritis / II型コラーゲン / MRI / 破骨細胞 / lprマウス / 骨破壊 / エストロジェン / 関節リウマチ / apoptosis / salivary gland / autommune diseases / a-fodrin / Sjogren's syndrome / 自己抗原 / ELISA / α-fodrin / Caspase / アポトーシス / 唾液腺 / 自己免疫疾患 / α-フォドリン / 歯科用金属 / 金属アレルギー / 国際シェーグレン症候群シンポジウム / 日本シェーグレン症候群研究会 / 個人調査表 / 現状調査表 / 改訂診断基準 / 査定調査 / 診断基準 Less

抗原特異的調節性T細胞による細胞免疫療法の開発Principal Investigator
- Principal Investigator
  
  林良夫
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  The University of Tokushima
Immunotherapeutic analysis using newly established murine models for Sjogren' s syndromePrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  The University of Tokushima
自己抗原に依存した未知の調節性T細胞に関する探索的研究Principal Investigator
- Principal Investigator
  
  林良夫
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  The University of Tokushima
Molecular analysis of pathogenesis on Sjogren's syndrome and its application of new diagnosis and therapyPrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshio
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  The University of Tokushima
Fasリガンド分子制御によるシェーグレン症候群治療法の研究開発Principal Investigator
- Principal Investigator
  
  林良夫
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokushima
Mechanism of bone destruction due to Rheumatoid Arthritis in the fields of Osteoimmunology
- Principal Investigator
  
  MORIYAMA Keiji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  The University of Tokushima
歯科用金属の溶出と局所免疫クロストークの相関性に関する研究
- Principal Investigator
  
  市川哲雄
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  補綴理工系歯学
- Research Institution
  The University of Tokushima
カスパーゼ活性阻害によるシェーグレン症候群制御法の開発Principal Investigator
- Principal Investigator
  
  林良夫
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  The University of Tokushima
シェーグレン症候群診断基準査定調査の企画
- Principal Investigator
  
  藤林孝司
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Dokkyo Medical University
SCREENING OF SALIVARY GLAND PROTEASE WHICH SPECIFICALLY CLEAVAGES SJOGREEN'S SYNDROME RELATED AUTOANTIGEN a-PODRIN FRAGMENT
- Principal Investigator
  
  ARAKAKI Rieko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokushima
Analysis of the mechanism of membranous proteolysis and the immunoregulation for Sjogren's syndromePrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshio
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  The University of Tokushima
Development of disease-specific diagnosis and immunotherapy for Sjogren's syndromePrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshio
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokushima
A study of molecular pathology in experimental Sjogren's syndrome in micePrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshio
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  The University of Tokushima
Experimental study of the therapeutic effect of synthetic peptide for Sjogren's syndromePrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshio
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  The University of Tokushima
Experimental study of pathogenesis and therapeutic effect for Sjogren's syndromePrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshio
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  The University of Tokushima
Establishment of animal model for Sjogren's syndrome in mutant micePrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshio
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  THE UNIVERSITY OF TOKUSHIMA
唾液腺ミュ-タントマウスに見られる形質発現調節異常の解析Principal Investigator
- Principal Investigator
  
  林良夫
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  The University of Tokushima
老化に伴う臓器局在性自己免疫疾患の発症機序に関する実験的研究Principal Investigator
- Principal Investigator
  
  林良夫
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
Immune Responses Associated with Killer-Lymphocyte Population in Oral Cancer and their Therapeutic Significance
- Principal Investigator
  
  SATO Mitsunobu
- Project Period (FY)
  1986 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  外科・放射線系歯学
- Research Institution
  The University of Tokushima

All 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book Patent

[Book] Handbook on Immunosenescence Basic understanding and clinical applications2009
- Author(s)
  Hayashi Y.
- Total Pages
  1652
- Publisher
  Springer Netherlands
- Data Source
  KAKENHI-PROJECT-21249090
[Book] Autoimmunity-Aging Mouse Model for Autoimmune Disease2009
- Author(s)
  Hayashi Y., et al
- Publisher
  Handbook on Immunosenescence Springe
- Data Source
  KAKENHI-PROJECT-17109016
[Book] Handbook on Immunosenescence Basic understanding and clinical applications2009
- Author(s)
  Hayashi Y.
- Total Pages
  1652
- Publisher
  Springer Netherlands
- Data Source
  KAKENHI-PROJECT-21659434
[Book] 口唇生検の診断「シェーグレン症候群の診断と治療」2009
- Author(s)
  林良夫等
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-17109016
[Book] 口腔内科2008
- Author(s)
  林良夫
- Publisher
  株式会社飛鳥出版室
- Data Source
  KAKENHI-PROJECT-17109016
[Book] Annual Review糖尿病・代謝・内分泌2006(エストロゲンと自己免疫疾患)2006
- Author(s)
  林良夫
- Total Pages
  6
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-17109016
[Journal Article] CCR7 with S1P1signaling through AP-1 for migration of Foxp3+ regulatory T-cells control autoimmune exocrinopathy2012
- Author(s)
  Ishimaru N, Yamada A, Nitta T, Arakaki R, Lipp M, Takahama Y, Hayashi Y
- Journal Title
  
  Am. J. Pathol
  
  Volume: 180 Pages: 199-208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] Autoimmune disease : Sjogren's syndrome2011
- Author(s)
  Hayashi Y, 他
- Journal Title
  
  Nihon Naika Gakkai Zasshi
  
  Volume: 10 Pages: 1262-1268
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] RANKLとFasによる免疫応答の制御2011
- Author(s)
  石丸直澄、井澤俊、林良夫
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 55 Pages: 142-147
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development2011
- Author(s)
  Lei Y, Mat Ripen A, Ishimaru N, Ohigashi I, Nagasawa T, Jeker L, Bosl M, Hollander GA, Hayashi Y, de Waal Malefyt R, Nitta T, Takahama Y
- Journal Title
  
  J. Exp. Med
  
  Volume: 208 Pages: 383-394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] A novel DC therapy with manipulation of MKK6 gene on Nickel allergy in mice2011
- Author(s)
  Watanabe M, Ishimaru N, Ashrin MN, Arakaki R, Yamada A, Ichikawa T, Hayashi Y
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] Atelocollagen-mediated systemic administration of myostatin-targeting siRNA improves muscular atrophy in caveolin-3-deficient mice2011
- Author(s)
  Kawakami E, Kinouchi N, Adachi T, Ohsawa Y, Ishimaru N, Ohuchi H, Sunada Y, Hayashi Y, Noji S
- Journal Title
  
  Dev Growth Differ
  
  Volume: 53(1) Pages: 48-54
- NAID
  10027899274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] Sjogren症候群2011
- Author(s)
  林良夫、新垣理恵子、石丸直澄
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 100 Pages: 1262-1268
- NAID
  10029097111
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] In situ patrolling of regulatory T cells is essential for protecting autoimmune exocrinopaty2010
- Author(s)
  Ishimaru N, Nitta T, Arakaki R, Yamada A, Lipp M, Takahama Y, Hayashi Y
- Journal Title
  
  PLoS One
  
  Volume: 5(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] 新生児におけるダイオキシンへの暴露と自己免疫病の発生2010
- Author(s)
  石丸直澄、小橋真之、山田安希子、新垣理恵子、林良夫
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 53(1) Pages: 92-96
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] Inflammatory disease and cancer with a decrease in Kupffer cell numbers in Nucling-knockout mice2010
- Author(s)
  Sakai T, Liu L, Teng X, Ishimaru N, Tran NH, Kim SM, Sano N, Hayashi Y, Kaji R, Fukui K.
- Journal Title
  
  Int. J. Cancer
  
  Volume: 126 Pages: 1079-1094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] Immunotherapeutic target in estrogen deficiency-dependent Sjogren' s syndrome-related manifestations2010
- Author(s)
  Arakaki R, Ishimaru N, Hayashi Y
- Journal Title
  
  Immunotherapy
  
  Volume: 2(3) Pages: 339-346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] Cathepsin L inhibition prevents murine autoimmune diabetes via suppression of CD8+ T cell activity2010
- Author(s)
  Yamada A, Ishimaru N, Arakaki R, Katunuma N, Hayashi Y
- Journal Title
  
  PLoS One
  
  Volume: 5(9)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] Role of plasmacytoid dendritic cells(pDCs) for aberrant class II expression in the exocrine glands from estrogen-deficient mice of healthy background2009
- Author(s)
  Arakaki R, Nagaoka A, Ishimaru N, Yamada A, Yoshida S, Hayashi Y
- Journal Title
  
  Am. J. Pathol
  
  Volume: 174 Pages: 1715-1724
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] Role of plasmacytoid dendritic cells for aberrant class II expression in exocrine glands from estrogen-deficient mice of healty background2009
- Author(s)
  Arakaki R, Nagaoka A, Ishimaru N, Yamada A, Yoshida S, Hayashi Y
- Journal Title
  
  Am. j. Pathol 174
  
  Pages: 1715-1715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109016
[Journal Article] ダイオキシンによる免疫異常2009
- Author(s)
  石丸直澄、林良夫
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 51(1) Pages: 60-65
- NAID
  40016464327
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] The role of fractalkine as accelerating factor on the autoimmune exocrinopathy in mice2009
- Author(s)
  Tsubota K, Nishiyama T, Mishima K, Inoue H, Doi T, Hattori Y, Kodama T, Higuchi A, Hayashi Y, Saito I
- Journal Title
  
  Invest. Ophthalmol. Vis. Sci
  
  Volume: 50 Pages: 4753-4760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] YKL-40 secreted from adipose tissue inhibits degradation of type I collagen2009
- Author(s)
  Iwata T, Kuwajima M, Sukeno A, Ishimaru N, Hayashi Y, Wabitsch M, Mizusawa N, Itakura M, Yoshimoto K.
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 388 Pages: 511-516
- NAID
  120005708871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] Neonatal explosure to low dose 2, 3, 7, 8-tetrachlorodibenzo-p-diozin causes autoimmunity due to the disruption of T cell tolerance2009
- Author(s)
  Ishimaru N, Takagi A, Kohashi M, Yamada A, Arakaki R, Kanno J, Hayashi Y.
- Journal Title
  
  J. Immunol
  
  Volume: 182 Pages: 6576-6586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] Sjogren症候群の発症とエストロゲン2009
- Author(s)
  石丸直澄、林良夫
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 51(4) Pages: 431-437
- NAID
  40016880980
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] 炎症性腸疾患におけるレギュラトリーT細胞2009
- Author(s)
  石丸直澄、林良夫
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 51(3) Pages: 301-306
- NAID
  40016608905
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] Neonatal exposure to low-dose 2, 3, 7, 8-tetrachlorcdibenzo-p-dioxin causes autoimmunity due to the disruption of T cell tolerance2009
- Author(s)
  Ishimaru N, Takaji A, Kohashi M,Yamada A, Arakaki R, Kanno J, Hayashi Y
- Journal Title
  
  J. Immunol 182
  
  Pages: 6576-6586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109016
[Journal Article] RANKLとFasシグナルクロストークによる樹状細胞の機能調節機構2009
- Author(s)
  井澤俊、石丸直澄、田中英二、林良夫
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 52(5) Pages: 471-477
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] Expression of the retinoblastoma protein RbAp48 in exocrine glands leads to Sjogren' s syndrome-like autoimmune exocrinopathy2009
- Author(s)
  Ishimaru N, Arakaki R, Yoshida S, Yamada A, Noji S, Hayashi Y
- Journal Title
  
  J. Exp. Med 205
  
  Pages: 2915-2927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109016
[Journal Article] Real-time in vivo imaging of p16Ink4a reveals cross talk with p532009
- Author(s)
  Yamakoshi K, Takahashi A, Hirota F, Nakayama R, Ishimaru N, Kubo Y, Mann DJ, Ohmura M, Hirao A, Saya H, Arase S, Hayashi Y, Nakao K, Matsumoto M, Ohtani N, Hara E.
- Journal Title
  
  J. Cell Biol
  
  Volume: 186 Pages: 393-407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] シェーグレン症候群2009
- Author(s)
  林良夫、石丸直澄、新垣理恵子
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 39 Pages: 80-82
- Data Source
  KAKENHI-PROJECT-21249090
[Journal Article] Effective treatment of a mouse model of Sjogren' s syndrome with oral administration of rebamipide2008
- Author(s)
  Kohashi M, Ishimaru N, Arakaki R ; Hayashi Y
- Journal Title
  
  Arthritis Rheum 58
  
  Pages: 389-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109016
[Journal Article] Development of inflammatory bowel disease in Long-Evans Cinnamon rats based on CD4^+CD25^+Foxp3^+ regulatory T cell dysfunction2008
- Author(s)
  Ishimaru N, Yamada A, Kohashi M, Arakaki R Takahashi T, Izumi K, Hayashi Y
- Journal Title
  
  J. Immunol 180
  
  Pages: 6997-7008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109016
[Journal Article] Crosstalk between RANKL and Fas signaling in dendritic cells controls immune tolerance2007
- Author(s)
  Izawa T, Ishimaru N, Moriyama K, Kohashi M, Arakaki R, Hayashi Y
- Journal Title
  
  Blood 1110
  
  Pages: 242-250
- NAID
  40016915514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109016
[Journal Article] Regulation of nave T cell function by the NF-kB2 pathway2006
- Author(s)
  Ishimaru N, Kishimoto H, Hayashi Y, Sprent J
- Journal Title
  
  Nature Immunol 7
  
  Pages: 763-771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109016
[Journal Article] Novel role of RbAp48 for tissue-specific. estrogen deficiency-dependent apoptosis in the exocrine glands2006
- Author(s)
  Ishimaru N, Arakaki R, Omotehara F, Yamada K, Mishima K, Saito I, Hayashi Y
- Journal Title
  
  Mol. Cell. Biol 26
  
  Pages: 2924-2935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109016
[Journal Article] CCR7-dependent cortex-to medulla migration of positively selected thymocytes is essential for establishing central tolerance2006
- Author(s)
  Kurobe H, Cunlan Liu C, UenoT, Saito F, Ohigashi I, Seach N, Arakaki R, Hayashi Y, Kitagawa T, Lipp M, Richard L. Boyd R, Takahama Y
- Journal Title
  
  Immunity 24
  
  Pages: 1-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109016
[Journal Article] Mutations in the fibroblast growth factor 10 gene are associated with aplasia of lacrimal' and salivary glands (ALSG)2005
- Author(s)
  Entesarian M, Matsson H, Klar J, Bergendal B, Olson L, Arakaki R, Hayashi Y, Ohuchi H, Falhat B, Bolstad AI, Jonsson R, Wahren-Herlenius M, Dahl N
- Journal Title
  
  Nature Genetics 37
  
  Pages: 125-127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109016
[Journal Article] Estrogen Deficiency Accelerates Murine Autoimmune Arthritis Associated with RANKL-Mediated Osteoclastogenesis.2004
- Author(s)
  Yoneda T, Izawa T, Moriyama K, Hayashi Y, et al.
- Journal Title
  
  Endocrinology 145(5)
  
  Pages: 2384-2391
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390637
[Patent] Composition containingα-fodrin, orα-fodrinfragment protein2004
- Inventor(s)
  HayashiY, HiromuSugino
- Industrial Property Rights Holder
  Yoshio Hayashi
- Filing Date
  2004-03-09
- Data Source
  KAKENHI-PROJECT-17109016
[Patent] 疾患の予防・治療剤及びそのスクリーニング方法」2003
- Inventor(s)
  林良夫
- Industrial Property Rights Holder
  興和株式会社
- Industrial Property Number
  2003-123959
- Filing Date
  2003-04-28
- Data Source
  KAKENHI-PROJECT-17109016
[Presentation] Salivary Gland and Autoimmunity2009
- Author(s)
  Hayashi Y.
- Organizer
  第11回The International Symposium on Exocrine Secretion(ISES)
- Place of Presentation
  Tokushima University
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-21249090
[Presentation] Salivary Gland and Autoimmunity2009
- Author(s)
  Hayashi Y.
- Organizer
  第11回 The International Symposium on Exocrine Secretion (ISES)
- Place of Presentation
  Tokushima University
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-21659434
[Presentation] Development of Autoimmune Exocrinopathy Resembling Sjogren's Syndrome in Rbap48 Transgenic Mice2007
- Author(s)
  Yoshio Hayashi
- Organizer
  AMERICAN COLLEGE OF RHEUMATOLOGY
- Place of Presentation
  New Boston Convention and Exhibition Center
- Year and Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-17109016
[Presentation] Development of autoimmune exocrinopathy resembling Sjogren's syndrome in RbAp48 transgenic mice2007
- Author(s)
  Hayashi Y
- Organizer
  The 71^<st> Annual Meeting of the American College of Rheumatology
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-17109016
[Presentation] Cathepsin L-inhibitor prevents proinsulin peptide processing and autoimmune diabetes in nonobase diabetic(NOD) mice2006
- Author(s)
  Hayashi Y. et.al.
- Organizer
  International Sympojium on Medical and Biological Perspective in Protease and Their Inhibitors
- Place of Presentation
  Awaji, Japan
- Data Source
  KAKENHI-PROJECT-17109016
[Presentation] Involvement of interstitial pneumonia in Sjogren's syndrome mouse model with aging2005
- Author(s)
  Hayashi Y. et.al.
- Organizer
  T Cell Immunity & Aging
- Place of Presentation
  Freudenstadt-Lauterbad
- Data Source
  KAKENHI-PROJECT-17109016
[Presentation] シェーグレン症候群発症の分子基盤2005
- Author(s)
  林良夫
- Organizer
  第94回日本病理学会総会
- Place of Presentation
  横浜
- Year and Date
  2005-04-14
- Data Source
  KAKENHI-PROJECT-17109016
[Presentation] Possible mechanism of autoimmune exocrinopathy resembling Sjogren's syndrome through RbAp48 overexpression2005
- Author(s)
  Hayashi Y. et.al.
- Organizer
  Gordon Research Conference on Salivary Glads & Exocrine Secretion
- Place of Presentation
  Ventura
- Data Source
  KAKENHI-PROJECT-17109016

1. ARAKAKI Rieko (00193061)

# of Collaborated Projects: 4 results

# of Collaborated Products: 38 results
2. ISHIMARU Naozumi (60314879)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
3. ARAKAKI Rieko (40231120)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. HAMANO Hironori (10238074)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. YANAGAI Kumiko (90294701)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. HANEJI Norio (30274228)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. YAMADA Akiko (70452646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. DEGUCHI Hiroyo (80227545)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MORIYAMA Keiji (20262206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. OBA Yasuo (40294706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HORIUCHI Shinya (70263861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KITASE Yukiho (70363166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAKAHASHI Takumi (30363154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SATO Mitsunobu (00028763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKEGAWA Yoshihiro (40035754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YANAGAWA Tetsuo (40136263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. YOSHIDA Hideo (30116131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 藤林孝司 (80013978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 宮坂信之 (30157622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 菅井進 (20064537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 坪田一男 (40163878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 市川哲雄 (90193432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 川本苗子 (40335823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 岡謙次 (40253215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 蟹谷英生 (10294711)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 中村隆範 (70183887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 斎藤一郎 (60147634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 大庭知子 (10274242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 三木善樹 (50294707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HAYASHI Yoshio 林 良夫

林 良夫 ハヤシ ヨシオ

Research Projects

Research Products

Co-Researchers

抗原特異的調節性T細胞による細胞免疫療法の開発Principal Investigator

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Immunotherapeutic analysis using newly established murine models for Sjogren' s syndromePrincipal Investigator

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自己抗原に依存した未知の調節性T細胞に関する探索的研究Principal Investigator

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Molecular analysis of pathogenesis on Sjogren's syndrome and its application of new diagnosis and therapyPrincipal Investigator

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Fasリガンド分子制御によるシェーグレン症候群治療法の研究開発Principal Investigator

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Mechanism of bone destruction due to Rheumatoid Arthritis in the fields of Osteoimmunology

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歯科用金属の溶出と局所免疫クロストークの相関性に関する研究

Principal Investigator

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カスパーゼ活性阻害によるシェーグレン症候群制御法の開発Principal Investigator

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シェーグレン症候群診断基準査定調査の企画

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SCREENING OF SALIVARY GLAND PROTEASE WHICH SPECIFICALLY CLEAVAGES SJOGREEN'S SYNDROME RELATED AUTOANTIGEN a-PODRIN FRAGMENT

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Analysis of the mechanism of membranous proteolysis and the immunoregulation for Sjogren's syndromePrincipal Investigator

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Development of disease-specific diagnosis and immunotherapy for Sjogren's syndromePrincipal Investigator

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A study of molecular pathology in experimental Sjogren's syndrome in micePrincipal Investigator

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HAYASHI Yoshio 林良夫

林良夫ハヤシヨシオ