SOMA Gen-Ichiro 杣源一郎

… Alternative Names

SOMA Genichiro 杣源一郎

杣源一郎

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Researcher Number	00158990
Other IDs
Affiliation (based on the past Project Information) *help	2009: 徳島文理大学, 人間生活学部・食物栄養学科, 教授(兼香川大学・医学部・総合免疫システム学講座・客員教授) 2008: 徳島文理大学, 家政学部 2007: 徳島文理大学, 家政学部, 教授 2002 – 2006: 徳島文理大学, 健康科学研究所, 教授 1989: Teikyo University, Biotechnolgy Research Center, Associate Professor, 生物工学研究センター, 助教授 1988: 帝京大学, 生物工学センター, 助教授 1986: 帝京大学, 生物工学センター, 助教授
Review Section/Research Field	Except Principal Investigator Biomedical engineering/Biological material science / Urology / General fisheries / Biomedical engineering/Biological material science / 医薬分子機能学 / Fisheries chemistry / Eating habits, studies on eating habits
Keywords	Except Principal Investigator PLGA / DDS / tuberculosis / phagocytosis / 結核菌 / 貪食 / 肺胞マクロファージ / TX-1877 / TX-2068 / LPS … More / Antitumor effect / Human urological cancer / Novel TNF / 増殖抑制 / ヌードマウス移植系 / 人尿路系悪性腫瘍 / 腫瘍壊死因子 / 抗腫瘍効果 / 人尿路性器癌 / 新規腫瘍壊死因子 / Recombinant TNF / mRNA expression / Transgenic / TNF alpha / Banded dogfish / Ayu fish / Zebrafish / Rainbow trout / CCケモカイン / 組換えニジマスTNF / 定量PCR法 / TNFレセプターデコイ / 組換えTNF / GFP / 組み換えTNF / mRNA発現 / トランスジェニック / TNFα / ドチザメ / アユ / ゼブラフィッシュ / ニジマス / tuberculosis therapy / alveolar macrophage / anti-tuberculosis agent / pulmonary delivery / リファンピシン / NR8383細胞株 / ポリ乳酸グリコール酸共重合体(PLGA) / 薬物送達システム(DDS) / ファゴソーム / PLGA微粒子製剤 / 微粒子製剤 / 結核治療 / 結核 / 抗結核薬 / 経肺投与 / microsphere / alveolar macrophages / 貧食 / 肺結核 / 粒子 / N-Acetylgalactosamine / Hypoxia Orientation / Macrophage / Hypoxic Cell Radiosensitizer / TX-2073 / GcMAF / 貪食活性 / N-アセチルガラクトサミン / 低酸素指向性 / マクロファージ / 低酸素細胞放射線増感剤 / 進化 / エンドルフィン(EP) / MSH / プロオピオメラノコルチン(POMC) / 細胞・組織 / 免疫学 / 栄養学 / CD14 / 腸管マクロファージ / 粘膜免疫機構 / 食と栄養 / 制癌剤 / トレハロース / ナノコンポジット微粒子 / 経肺吸収 / 肺がん / 経気道投与 / 経肺吸収製剤 / ナノ粒子 / がん / 薬学 / 薬物送達システム Less

Analysis of CD14 expression for the hyporesponsiveness against LPS in intestinal macrophage
- Principal Investigator
  
  NAKATA Kazue
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Hagoromo International University
Pulmonary delivery of nanocomposite particles for the treatment oflung carcinoma
- Principal Investigator
  
  MAKINO Kimiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo University of Science
Pulmonary delivery of microspheres loaded with antituberculosis agents to alveolar macrophages for development of antituberculosis therapy
- Principal Investigator
  
  TERADA Hiroshi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo University of Science
Studies on the structure and function of tumor necrosis factor (TNF) in fish
- Principal Investigator
  
  NAKANISHI Teruyuki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General fisheries
- Research Institution
  Nihon University
Design of hypoxic cell radiosensitizer utilized for hypoxia orientation of macrophage
- Principal Investigator
  
  HORI Hitoshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  The University of Tokushima
Use of microsphere technology for targeting to Mycobacterium tuberculosis-infected alveolar macrophages
- Principal Investigator
  
  MAKINO Kimiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo University of Science
Anti-tumor effect of novel tumor necrosis factor (TNF-S) to human urological cancer in vitro and in vivo
- Principal Investigator
  
  KATO Mikio
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Saitama Medical School
白ザケ脳下垂体ホルモン遺伝子の構造解析とこれを用いた育種への応用
- Principal Investigator
  
  安藤俊夫
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Meiji Pharmaceutical University

All 2010 2009 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

[Book] Recent advances in antibacterial and antifungal treatment an DDS2005
- Author(s)
  K.Makino, G.Soma, H.Terad
- Total Pages
  283
- Publisher
  N.T.S
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300170
[Book] 抗菌・抗カビの最新技術とDDSの実際2005
- Author(s)
  牧野公子, 杣源一郎, 寺田弘
- Total Pages
  283
- Publisher
  エヌ・ティー・エス
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Intercellular localization of CD14 protein in intestinal macrophages.2009
- Author(s)
  N. Yoshioka, Y. Taniguchi, A. Yoshida, K. Nakata, T. Nishizawa, H. Inagawa, C. Kohchi, G. Soma.
- Journal Title
  
  Anricancer Research 29
  
  Pages: 865-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700607
[Journal Article] Phagocytic activity of alveolar macrophages toward polystyrene latex microspheres and PLGA microspheres loaded with anti-tuberculosis agent2007
- Author(s)
  Taizo Hasegawa, Keiji Hirota, Keishiro Tomoda, Fuminori Ito, Hiroyuki Inagawa, Chie Kochi, Gen-Ichiro Soma, Kimiko Makino and Hiroshi Terada
- Journal Title
  
  Colloids and Surfaces B : Biointerfaces 60
  
  Pages: 221-228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Phagocytotic activity of alveolar macrophages toward polystyrene latex microspheres and PLGA microspheres loaded with anti-tuberculosis---.2007
- Author(s)
  T. Hasegawa, G. Soma, K. Makino, H. Terada,
- Journal Title
  
  Colloids and Surfaces B: Biointerfaces 60(2)
  
  Pages: 221-228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Optimum conditions for efficient phagocytosis of rifampicin-loaded PLGA microspheres by alveolar macrophages2007
- Author(s)
  Keiji Hirota, Taizo Hasegawa, Hideyuki Hinata, Fuminori Ito, Hiroyuki Inagawa, Chie Kochi, Gen-Ichiro Soma, Kimiko Makino and Hiroshi Terada
- Journal Title
  
  Journal of Controlled Release 119
  
  Pages: 69-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300177
[Journal Article] Cloning and characterization of a TNF-like protein of Plecoglossus altivelis (ayu fish)2006
- Author(s)
  Uenobe, M., C.Kohchi, N.Yoshioka, A.Yuasa, H.Inagawa, G-I.Soma, et al.
- Journal Title
  
  Fish & Shellfish Immunol. (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Cytotoxic activities of fish leucocytes.2006
- Author(s)
  Fischer U, Utke K, Somamoto T, Kollner B, Ototake M, Nakanishi T.
- Journal Title
  
  Fish Shellfish Immunol. 20(2)
  
  Pages: 209-226
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Inherent potential for production of tumor necrosis factor-α by human intestinal macrophages2006
- Author(s)
  Nakata, K., H.Inagawa, T.Nishizawa, T.Honda, C.Kohchi,.G-I.Soma, et al.
- Journal Title
  
  Int J Colorectal Dis.
  
  Pages: 1-9
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Inherent potential for production of tumor necrosis factor-a by human intestinal macrophages2006
- Author(s)
  Nakata, K., H.Inagawa, T.Nishizawa, T.Honda, C.Kohchi,.G-I.Soma, et al.
- Journal Title
  
  Int J Colorectal Dis. 21
  
  Pages: 339-347
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Cloning and characterization of a LPS-regulatory gene having an LPS binding domain in kuruma prawn Marsupenaeus japonicus.2006
- Author(s)
  Nagoshi, H., H.Inagawa, K.Morii, H.Harada, C.Kohchi, T.Nishizawa, Y.Taniguchi, M.Uenobe, T.Honda, M.Kondoh, Y.Takahashi, G-I.Soma
- Journal Title
  
  Molecular Immunology 43
  
  Pages: 2061-2069
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Specific messenger RNA expression for signal transduction molecules by lipopolysaccharide in intestinal macrophages.2006
- Author(s)
  Nakata K, Inagawa H, Nishizawa T, Kohchi C, Soma GI.
- Journal Title
  
  Clin Exp Immunol. 143(3)
  
  Pages: 484-493
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Inherent potential for production of tumor necrosis factor-□ by human intestinal macrophages.2006
- Author(s)
  Nakata, K., H.Inagawa, T.Nishizawa, T.Honda, C.Kohchi, Y.Tonomoto, H.Yoshimura, N.Nagase, S.Natori, H.Terada, G-I.Soma
- Journal Title
  
  Int J Colorectal Dis. 21
  
  Pages: 339-347
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Cloning and characterization of a LPS-regulatory gene having an LPS binding domain in kuruma prawn Marsupenaeus Japonicus.2006
- Author(s)
  Nagoshi, H., H.Inagawa, K.Morii, H.Harada, C.Kohchi, G-I.Soma, et al.
- Journal Title
  
  Molecular Immunology 43
  
  Pages: 2061-2069
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Molecular cloning and expression analysis of a macrophage-colony stimulating factor receptor-like gene from rainbow trout, Oncorhynchus mykiss2005
- Author(s)
  Honda T, Nishisawa T, Uenobe M, Kochi C, Kuroda A, Ototake M, Nakanishi T, Yokomizo Y, Takahashi Y, Inagawa H, Soma G-I.
- Journal Title
  
  Molecular Immunology 42
  
  Pages: 1-8
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Establishment of In Vitro Model using NR8383 Cells and Mycobacterium Bovis Calmette-Guerin that Mimes a Chronic Infection of Mycobaceterium Tuberculosis.2005
- Author(s)
  M.Hino, Kohchi, T.Nishizawa, H.Inagawa, H.Hori, K.Makino, H.Terada, G.Soma
- Journal Title
  
  In Vivo. 19
  
  Pages: 821-830
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Molecular cloning and expression analysis of a macrophage-colony stimulating factor receptor-like gene from rainbow trout, Oncorhynchus mykiss.2005
- Author(s)
  Honda T, Nishizawa T, Uenobe M, Kohchi C, Kuroda A, Ototake M, Nakanishi T, Yokomizo Y, Takahashi Y, Inagawa H, G Soma
- Journal Title
  
  Mol Immunol. 42(1)
  
  Pages: 1-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Innate-immune Therapy for Lung Carcinoma Based on Tissue-macrophage Activation with Lipopolysaccharide.2005
- Author(s)
  M.Hino, C.Kouchi, T.Nishizawa, H.Inagawa, H.Hori, K.Makino, H.Terada, G.Soma
- Journal Title
  
  Anticancer Res. 25
  
  Pages: 3747-3754
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Molecular cloning and expression analysis of a macrophage-colonystimulating factor receptor-like gene from rainbow trout, Oncorhynchus mykiss2005
- Author(s)
  Honda T, Nishisawa T, Uenobe M, Kochi C, Kuroda A, Ototake M, Nakanishi T, Yokomizo Y, Takahashi Y, Inagawa H, Soma G-I.
- Journal Title
  
  Molecular Immunology 42
  
  Pages: 1-8
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Molecular cloning and characterization of two types of CD8α from ginbuna crucian carp, Carassius auratus langsdorfii.2005
- Author(s)
  Somamoto, T., Y.Yoshiura, T.Nakanishi, M.Ototake
- Journal Title
  
  Dev. Comp. Immunol. 29
  
  Pages: 693-702
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Profile of cytokines produced in tumor tissue after administration of cyclophosphamide in a combination therapy with tumor necrosis factor2004
- Author(s)
  Takiguchi K, Nakamoto T, Inagawa H, Kochi C, Nishizawa, T, Nagasue N, Soma G-I.
- Journal Title
  
  Anticancer Research 24(3)
  
  Pages: 1823-1828
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Correlation of histological localization of tumor-associated macrophages with clinicopathological features in endometrial cancer2004
- Author(s)
  Ohno S, Ohno Y, Suzuki N, Kamei T, Koike K, Inagawa H, Kohchi C, Soma G-I, Inoue M.
- Journal Title
  
  Anticancer Reseach 24(5C)
  
  Pages: 3335-3342
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Efficient intracellular delivery of rifampicin to alveolar macrophages using rifampicin-loaded PLGA microspheres : Effects of molecular weight and composition of PLGA on release of rifampicin.2004
- Author(s)
  Makino K, Nakajima T, Shikamura M, Ito F, Ando S, Kochi C, Inagawa H, Soma G-I, Terada H.
- Journal Title
  
  Colloids and Surfaces B : Biointerfaces 36
  
  Pages: 35-42
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Utilization of macrophages in anticancer therapy : the macrophage network theory.2004
- Author(s)
  C.Kochi, H.Inagawa, A.Yoshida, H.Terada, M.Makino, G.Soma
- Journal Title
  
  Anticancer Res. 24
  
  Pages: 3311-3320
- Data Source
  KAKENHI-PROJECT-15300170
[Journal Article] Cloning and characterization of a LPS-regulatory gene having an LPS binding domain in kuruma prawn Marsupenaeus japonicus.
- Author(s)
  Nagoshi, H., H.Inagawa, K.Morii, H.Harada, C.Kohchi, G-I.Soma, et al.
- Journal Title
  
  Molecular Immunology (印刷中)
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Cloning and characterization of a TNF-like protein of Plecoglossus altivelis (ayu fish)
- Author(s)
  Uenobe, M., C.Kohchi, N.Yoshioka, A.Yuasa, H.Inagawa, G-I.Soma, et al.
- Journal Title
  
  Fish & Shellfish Immunol. (発表予定)
- Data Source
  KAKENHI-PROJECT-15380136
[Journal Article] Expression profiles of TCRβ and CD8α mRNA correlate with virus-specific cell-mediated cytotoxic activity in ginbuna crucian carp
- Author(s)
  Somamoto, T., Y.Yoshiura, A.Sato, T.Nakanishi, N.Okamoto, M.Ototake
- Journal Title
  
  Virology (印刷中)
- Data Source
  KAKENHI-PROJECT-15380136
[Patent] 治療薬2003
- Inventor(s)
  寺田弘, 牧野公子, 杣源一郎
- Industrial Property Rights Holder
  寺田弘, 牧野公子, 杣源一郎
- Filing Date
  2003-08-27
- Data Source
  KAKENHI-PROJECT-15300170
[Presentation] Analysis of CD14 expression for the hyporesponsiveness against LSP in intestinal macrophage2010
- Author(s)
  中田和江、山本耕一郎、吉岡典子、杣源一郎
- Organizer
  第83回日本細菌学会総会
- Place of Presentation
  神奈川
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20700607
[Presentation] 腸管マクロファージのLPS不応答に関するメカニズム解析2009
- Author(s)
  吉岡典子、谷口芳枝、吉田彩、中田和江、西澤孝志、稲川裕之、河内千恵、平島光臣、杣源一郎
- Organizer
  第13回バイオ治療法研究会学術集会
- Place of Presentation
  香川
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20700607
[Presentation] The 5th Joint Conference on Nutrition of Okayama Prefectural University, Woosong University and Sichuan University2009
- Author(s)
  K. Nakata, H. Inagawa, C. Kohchi, Y. Taniguchi, N. Yoshioka, G. Soma
- Organizer
  The 5th Joint Conference on Nutrition of Okayama Prefectural University, Woosong University and Sichuan University
- Place of Presentation
  Sichuan University
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-20700607

1. TERADA Hiroshi (00035544)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
2. MAKINO Kimiko (40147509)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
3. KOJIMA Shuji (90119579)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 深井文雄 (90124487)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NAKATA Kazue (60411740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. CHIE Kohchi (00274142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. HORI Hitoshi (90119008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAGASAWA Hideko (90207994)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. UTO Yoshihiro (20304553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OHSHIMA Hiroyuki (60176873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. IKEKITA Masahiko (70138981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SHINOHARA Yasuo (60226157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NAKANISHI Teruyuki (00322496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
14. YOSHIURA Yasutoshi (90372052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KATO Mikio (80096213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 友田敬士郎 (70516400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 廣田慶司 (50516359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. 伊藤史典 (10366429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. SONAVANE Ganeshchandra (90449231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 安藤俊夫 (20012693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 石井一行 (90158741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 井上裕基 (50333571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 吉浦康壽

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

SOMA Gen-Ichiro 杣 源一郎

SOMA Genichiro 杣 源一郎

杣源 一郎

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[Book] Recent advances in antibacterial and antifungal treatment an DDS2005

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[Book] 抗菌・抗カビの最新技術とDDSの実際2005

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[Journal Article] Intercellular localization of CD14 protein in intestinal macrophages.2009

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[Journal Article] Phagocytic activity of alveolar macrophages toward polystyrene latex microspheres and PLGA microspheres loaded with anti-tuberculosis agent2007

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[Journal Article] Phagocytotic activity of alveolar macrophages toward polystyrene latex microspheres and PLGA microspheres loaded with anti-tuberculosis---.2007

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[Journal Article] Optimum conditions for efficient phagocytosis of rifampicin-loaded PLGA microspheres by alveolar macrophages2007

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[Journal Article] Cloning and characterization of a TNF-like protein of Plecoglossus altivelis (ayu fish)2006

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[Journal Article] Cytotoxic activities of fish leucocytes.2006

SOMA Gen-Ichiro 杣源一郎

SOMA Genichiro 杣源一郎

杣源一郎