Tano Keizo 田野恵三

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TANO Keizo 田野恵三

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Researcher Number	00183468
Other IDs
Affiliation (Current)	2025: 大阪公立大学, 大学院理学研究科 , 客員研究員
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪公立大学, 大学院理学研究科, 客員研究員 2020 – 2021: 大阪府立大学, 理学(系)研究科(研究院), 客員研究員 2017 – 2020: 京都大学, 複合原子力科学研究所, 准教授 2007 – 2017: Kyoto University, Research Reactor Institute, Associate Professor 1996 – 2006: 京都大学, 原子炉実験所, 助教授 1995: 京都大学, 原子炉実験所, 助手
Review Section/Research Field	Principal Investigator Basic Section 63020:Radiation influence-related / Risk sciences of radiation/Chemicals / Risk sciences of radiation and chemicals / 環境影響評価(含放射線生物学) Except Principal Investigator 環境影響評価(含放射線生物学) / Radiation science / Risk sciences of radiation/Chemicals / Basic Section 52040:Radiological sciences-related / Tumor biology / Cell biology / 広領域 / Tumor biology
Keywords	Principal Investigator 細胞内微細環境 / DNA損傷修復 / ビグアノイド薬剤 / 活性酸素種 / 微細環境 / 細胞 / 染色体断裂 / DNAタンパククロスリンク損傷 / 腫瘍細胞内微細環境 / 国際情報交換、米国 … More / 細胞内至適環境 / ラジカルスカベンジャー / 細胞内至適環境維持 / 生物影響 / 修復 / 塩基損傷修復 / メチルプリンDNAグリコシラーゼ … More Except Principal Investigator 休止期腫瘍細胞 / 中性子捕捉療法 / homologous recombination / DT40 / 低温度温熱処置 / 腫瘍内微小環境 / 線量率効果 / p53 status / DNA二重鎖切断 / ニワトリ細胞株 / 低酸素細胞毒 / UBC13 / H2AX / non-homologous end-joining / sublethal damage repair / DNA double-strand break / 突然変異 / HPLC / 急性低酸素領域 / 放射線治療生物学 / メトフォルミン / ティラパザミン / 腫瘍不均一性 / CBE値 / 酸素化休止期腫瘍細胞 / 急性低酸素細胞分画 / 酸素化休止期腫瘍細胞分画 / 局所腫瘍制御 / 低酸素腫瘍細胞 / 癌幹細胞 / 相同組換え修復 / 放射線損傷からの回復現象 / 低酸素誘導因子 / 放射線障害からの回復現象 / 腫瘍不均一性, / 化合物生物学的効果比 / ホウ素中性子捕捉療法 / 温熱治療 / 癌幹細胞性 / 遠隔転移抑制能 / ピモニダゾール / 低グルコース環境 / HIF-1α / ゲノム編集技術 / 転移能抑制 / がん微小環境 / 硼素中性子捕捉療法 / ゲノム改変操作 / 転移 / Non-homologous end joining repair / Accelerated carbon ion beam irradiation / Newly-developed ^<10>B-carrier / transferrin-pendant-type polyethyleneaqlycol liposome / Mild temperature hyperthermia / Hypoxic cell cytotoxin / Reduced dose-rate irradiation / Quieseent cell / トランスフェリン結合PEGリポソーム / 血管標的物質 / 連続的皮下投与 / 低酸素特異的細胞毒 / 照射線量率効果 / 原子炉中性子線照射 / 高LET放射線 / 非相同末端結合 / 潜在的致死的障害からの回復 / 非相同末端結合による回復 / 新規中性子捕捉化合物 / 加速炭素イオン線照射 / トランスフェリン結合PEGリボソーム / 低減線量率照射 / translesion synthesis / Laser induced damage / Ubiqutine / Polymerase Q / DSB repair / ポリメラーゼQ / 緑色蛍光蛋白 / Rad51 / DNA修復 / Postreplication repair / Cisplatin / rev3 / rad30 / Translesion DNA synthesis / TLS polymerases / 損傷乗り越えポリメラーゼ / 損傷乗り越え修復 / タモキシフェン / 染色体安定性 / Rev3 / 複製フォーク停止 / 損傷乗り換え修復 / 相同組換え / ニワトリDT40 / low dose rate effects / knockout mutant / 非相同端末結合修復 / 低線量率照射 / Knockout mutant / エルカインド回復 / 潜在致死傷害回復 / 分割照射回復 / 端末結合修復 / 相同組換修復 / DNA2重鎖切断 / ニワトリ白血病細胞株 / photosensitization / reactive oxygen species / base change / DNA damage / UV senstivity / oxidative damage / mutation / cyanobacteria / 光合成 / DNAの傷害 / 遺伝子 / 活性酵素 / pUC303 / Synechococcus / らん藻 / 酸化的傷害 / 光増感反応 / DNA傷害 / 塩基置換 / 紫外線感受性 / シアノバクテリア / 酸化的損傷 / 活性酸素 / rare earth element / Mass Production / ^<195>mPt-CDDP / ^<195>mPt / 254-S / PWA-2114R / カルボプラチン / シスプラチン / ^<195M>Pt / 希土類元素 / 大量合成 / ^<195m>Pt-CDDP / ^<195m>Pt / mAMSA / Near-UV / x-rays / 8-Hydoroxyguanine / glutathione peroxidase / superoxide dismutase / Catalase / 培養加齢 / スーパーオキサイド。ディスムターゼ / カタラーゼ / スーパーオキサイド・ディスムターゼ / グルタチオン・パーオキシターゼ / 8-ハイドロオキシグアニン / 腫瘍血管正常化 / ビグアナイド系抗糖尿病薬剤 / HIF-1 alpha / サリドマイド / 低酸素領域 / サイクロデキストリン / インテグリンαvβ3受容体 / 中性子捕捉療法(BNCT) / L-para-boronophenylalanin-10B / sodium borocaptate-10B(BSH) / 中性子捕捉反応 / 加速炭素イオン線 / 分割ウォルトマニン投与 / ウォルトマニン / ベバシツマブ / 遠隔転移制御 / 腫瘍血管正常化現象 / 慢性低酸素 / 急性低酸素 / 加速炭素線ビーム / 腫瘍内酸素化状態 / 低酸素細胞毒薬剤 / ヘキサメチレンテトラミン / 遠隔転移 / 慢性低酸素細胞 / 急性低酸素細胞 / 線エネルギー付与(LET) / 酸素効果 / 血管新生阻害剤 / 硼素中性子捕捉療法(BNCT) / 遠隔転移抑制効果 / 局所腫瘍制御効果 / 遠隔転移抑制 / RBE / LET / 過酸化水素 Less

Biguanide系薬剤Metforminの腫瘍内環境特性による細胞致死と抗腫瘍免疫誘導の解析Principal Investigator
- Principal Investigator
  
  田野恵三
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Osaka Metropolitan University
Interrelationship analysis of the characteristics of quiescent tumor cells with tumor heterogeneity and cancer stem cell nature, referring to application to cancer therapy
- Principal Investigator
  
  増永慎一郎
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
  Kyoto University
Analyses of selective cytotoxicity of the anti-diabetic biguanide drug, Metformin, in solid tumor specific microenvironmentPrincipal Investigator
- Principal Investigator
  
  TANO Keizo
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
  Kyoto University
Analysis of neoplastic cell-specific fatal effects with reactive oxygen species abnormality derived from compound from plant species, piperlonguminePrincipal Investigator
- Principal Investigator
  
  Tano Keizo
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyoto University
An attempt to achieve both controlling local tumors and repressing distant metastases through exploiting analytical findings concerning characteristics of intratumor microenvironment
- Principal Investigator
  
  Masunaga Shin-ichiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kyoto University
An attempt to improve the possibilities of controlling local tumors through taking it into account to increase the sensitivity of oxic quiescent tumor cells
- Principal Investigator
  
  Masunaga Shin-ichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Biological impact Mechanism maintenance and assessment of biological impact of intracellular reactive oxygen species produced by normal physiological reactionPrincipal Investigator
- Principal Investigator
  
  Tano Keizo
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Exploration and exploit of intratumor microenvironment for both controlling local tumors and reducing distant metastatic potential
- Principal Investigator
  
  MASUNAGA Shin-ichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kyoto University
Characterization and biological assessment of DNA-Protein crosslink repair in vertebrate cellsPrincipal Investigator
- Principal Investigator
  
  TANO Keizo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Analyzing and exploiting the characteristics of intratumor quiescent cells in search of the potential as a cancer stem cell
- Principal Investigator
  
  MASUNAGA Shin-Ichiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Analysis of the effect of reduced dose rate and fractionated irradiation, including the effectoniniraturnor quiescent cells
- Principal Investigator
  
  MASUNAGA Shinichiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Bio-imaging of DNA repair machinery
- Principal Investigator
  
  SONODA Eiichiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
LET増加に伴うRBEの上昇はDNA二重鎖切断のエラー修復で説明できるか
- Principal Investigator
  
  内海博司
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Analysis of error-prone polymerases in vertebrate cells
- Principal Investigator
  
  SONODA Eiichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
Role of DNA double-strand break repair on low dose rate effects
- Principal Investigator
  
  UTSUMI Hiroshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  KYOTO UNIVERSITY
低線量放射線と酸化的代謝による傷害とは同じか違うか
- Principal Investigator
  
  UTSUMI Hiroshi
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Kyoto University
DNA repair research using DNA double-strand break repair-gene knockout mutants
- Principal Investigator
  
  UTSUMI Hiroshi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  KYOTO UNIVERSITY
Mutational Specificity of Photosynthetic Organism, Cyanobacterium Synechococcus at Molecular Level
- Principal Investigator
  
  TAKIMOTO Koichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Yamaguchi University
Establishment and Characterization of Hypocatalasemic Mouse Cell
- Principal Investigator
  
  UTSUMI Hiroshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  KYOTO UNIVERSITY
Trial manufacture of the automatic and remote-controlled apparatus for the mass production of ^<195>mpt radiolabeled compounds
- Principal Investigator
  
  AKABOSHI Mitsuhiko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  広領域
- Research Institution
  KYOTO UNIVERSITY
環境要因により生じる多様なDNA塩基損傷を除去する酵素の研究Principal Investigator
- Principal Investigator
  
  田野恵三
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Kyoto University

[Journal Article] SPRTN and TDP1/TDP2 Independently Suppress 5-Aza-2′-deoxycytidine-Induced Genomic Instability in Human TK6 Cell Line2022
- Author(s)
  Nakano Toshiaki，Moriwaki Takahito，Tsuda Masataka，Miyakawa Misa，Hanaichi Yuto，Sasanuma Hiroyuki，Hirota Kouji，Kawanishi Masanobu，Ide Hiroshi，Tano Keizo，Bessho Tadayoshi
- Journal Title
  
  Chemical Research in Toxicology
  
  Volume: 35 Issue: 11 Pages: 2059-2067
- DOI
  10.1021/acs.chemrestox.2c00213
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11640, KAKENHI-PROJECT-21K12248, KAKENHI-PROJECT-19KK0210, KAKENHI-PROJECT-20H04337, KAKENHI-PROJECT-21K19235, KAKENHI-PROJECT-20K17055
[Journal Article] PRDX1 is essential for the viability and maintenance of reactive oxygen species in chicken DT402021
- Author(s)
  Moriwaki Takahito、Yoshimura Akari、Tamari Yuki、Sasanuma Hiroyuki、Takeda Shunichi、Seki Masayuki、Tano Keizo
- Journal Title
  
  Genes and Environment
  
  Volume: 43 Issue: 1 Pages: 1-8
- DOI
  10.1186/s41021-021-00211-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04267, KAKENHI-PROJECT-18K11640, KAKENHI-PROJECT-19K07647, KAKENHI-PROJECT-20K17055, KAKENHI-PROJECT-16H06279
[Journal Article] An attempt to improve the therapeutic effect of boron neutron capture therapy using commonly employed 10B-carriers based on analytical studies on the correlation among quiescent tumor cell characteristics, tumor heterogeneity and cancer stemness2020
- Author(s)
  Shin-ichiro Masunaga, Yu Sanada, Keizo Tano, Yoshinori Sakurai, Hiroki Tanaka, Takushi Takata, Minoru Suzuki, Koji Ono
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 61 Issue: 6 Pages: 876-885
- DOI
  10.1093/jrr/rraa048
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11640, KAKENHI-PROJECT-19K08134, KAKENHI-PROJECT-19K08171
[Journal Article] Participation of TDP1 in the repair of formaldehyde-induced DNA-protein cross-links in chicken DT40 cells2020
- Author(s)
  Toshiaki Nakano, Mahmoud I. Shoulkamy, Masataka Tsuda, Hiroyuki Sasanuma, Kouji Hirota, Minoru Takata, Shin-ichiro Masunaga, Shunichi Takeda, Hiroshi Ide, Tadayoshi Bessho, Keizo Tano
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 6 Pages: 0234859-0234859
- DOI
  10.1371/journal.pone.0234859
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11640, KAKENHI-PROJECT-19K08171, KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-18H03374, KAKENHI-PROJECT-19H04267, KAKENHI-PROJECT-19K22561
[Journal Article] Effects of p53 status of tumor cells and combined treatment with mild hyperthermia, wortmannin or caffeine on recovery from radiation-induced damage2019
- Author(s)
  Masunaga S, Tano K, Sanada Y, Suzuki M, Takahashi A, Ohnishi K and Ono K
- Journal Title
  
  World J. Oncol.
  
  Volume: 10 Issue: 3 Pages: 132-141
- DOI
  10.14740/wjon1203
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11640, KAKENHI-PROJECT-19K08171
[Journal Article] Usefulness of combination with both continuous administration of hypoxic cytotoxin and mild temperature hyperthermia in boron neutron capture therapy in terms of local tumor response and lung metastatic potential2019
- Author(s)
  Masunaga S, Sakurai Y, Tanaka H, Takata T, Suzuki M, Sanada Y, Tano K, Maruhashi A and Ono K
- Journal Title
  
  Int. J. Radiat. Biol.
  
  Volume: 95 Issue: 12 Pages: 1708-1717
- DOI
  10.1080/09553002.2019.1666214
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11640, KAKENHI-PROJECT-19K08171
[Journal Article] Disruption of Hif-1α enhances cytotoxic effects of metformin in murine squamous cell carcinoma.2018
- Author(s)
  Sanada Y, Sasanuma H, Takeda S, Tano K, Masunaga S.
- Journal Title
  
  Int J Radiat Biol
  
  Volume: 94 Issue: 1 Pages: 88-96
- DOI
  10.1080/09553002.2018.1409443
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04295, KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-18K11640, KAKENHI-PROJECT-16H02953
[Journal Article] The Effect of p53 Status on Radio-Sensitivity of Quiescent Tumor Cell Population Irradiated With γ-Rays at Various Dose Rates.2018
- Author(s)
  Masunaga S, Kobayashi J, Tano K, Sanada Y, Suzuki M, Ono K.
- Journal Title
  
  J Clin Med Res.
  
  Volume: 10 Issue: 11 Pages: 815-821
- DOI
  10.14740/jocmr3610w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04978, KAKENHI-PROJECT-15K00537, KAKENHI-PROJECT-15H04295
[Journal Article] Effect of a change in reactor power on response of murine solid tumors in vivo, referring to impact on quiescent tumor cell population.2018
- Author(s)
  Masunaga S, Sakurai Y, Tanaka H, Takata T, Suzuki M, Sanada Y, Tano K, Maruhashi A, Ono K.
- Journal Title
  
  Int J Radiat Biol
  
  Volume: Dec 17 Issue: 5 Pages: 1-28
- DOI
  10.1080/09553002.2019.1558300
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04295, KAKENHI-PROJECT-18K11640, KAKENHI-PROJECT-19K08171
[Journal Article] Cytotoxicity of tirapazamine (3-amino-1, 2, 4- benzotriazine-1, 4-dioxide)-induced DNA damage in chicken DT40 cells.2017
- Author(s)
  Moriwaki T, Okamoto S, Sasanuma H, Nagasawa H, Takeda S, Masunaga S, Tano K
- Journal Title
  
  Chem Res Toxicol.
  
  Volume: 30 Issue: 2 Pages: 699-704
- DOI
  10.1021/acs.chemrestox.6b00417
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-15K00537
[Journal Article] Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts2017
- Author(s)
  Caglayan M, Prasad R, Krasich R, Longley MJ, Kadoda K, Tsuda M, Sasanuma H, Takeda S, Tano K, Copeland WC and Wilson SH
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 45 Issue: 17 Pages: 10079-10088
- DOI
  10.1093/nar/gkx654
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00537, KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-16H02953
[Journal Article] Effect of Tirapazamine, Metformin or Mild Hyperthermia on Recovery from Radiation-Induced Damage in Pimonidazole-Unlabeled Quiescent Tumor Cells2017
- Author(s)
  Masunaga S, Tano K, Sanada Y, Sakurai Y, Tanaka H, Suzuki M, Kondo N, Watanabe T, Takata T, Maruhashi A and Ono K
- Journal Title
  
  World J. Oncol.
  
  Volume: 8 Issue: 5 Pages: 137-146
- DOI
  10.14740/wjon1058w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00537, KAKENHI-PROJECT-15H04295
[Journal Article] Selective cytotoxicity of the anti-diabetic drug, metformin, in glucose-deprived chicken DT40 cells2017
- Author(s)
  Kadoda K, Moriwaki T, Tsuda M, Sasanuma H, Ishiai M, Takata M, Ide H, Masunaga S, Takeda S and Tano K
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 9 Pages: e0185141-e0185141
- DOI
  10.1371/journal.pone.0185141
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00537, KAKENHI-PROJECT-15H04295, KAKENHI-PUBLICLY-16H01642, KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-16H02953
[Journal Article] Effect of oxygen pressure during incubation with a 10B-carrier on 10B uptake capacity of cultured p53 wild-type and mutated tumor cells: dependency on p53 status of tumor cells and types of 10B-carriers2016
- Author(s)
  Masunaga S, Tatebe H, Nishimura Y, Tano K, Sanada Y, Moriwaki T, Sakurai Y, Tanaka H, Suzuki M, Kondo N, Maruhashi A and Ono K
- Journal Title
  
  International Journal of Radiation Biology
  
  Volume: 92 Issue: 4 Pages: 187-194
- DOI
  10.3109/09553002.2016.1137104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K00537, KAKENHI-PROJECT-26670556, KAKENHI-PROJECT-15H04295, KAKENHI-PROJECT-24510072
[Journal Article] 「臓器温存治療を目指して」治療生物学的および放射線治療医的視点から見た中性子捕捉療法の特性2016
- Author(s)
  増永慎一郎、鈴木　実、田野恵三、真田悠生、小野公二
- Journal Title
  
  日本口腔腫瘍学会誌
  
  Volume: 28 Pages: 134-147
- Data Source
  KAKENHI-PROJECT-26670556
[Journal Article] 腫瘍内環境とがん細胞増感の試み2015
- Author(s)
  真田悠生、森脇隆宏、田野恵三、増永慎一郎
- Journal Title
  
  放射線生物研究(Radiation Biology Research Communications)
  
  Volume: 50 Pages: 148-172
- NAID
  40020692187
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04295
[Journal Article] The effect of p53 status of tumor cells on radiosensitivity of irradiated tumors with carbon-ion beams compared with γ-rays or reactor neutron beams2015
- Author(s)
  Masunaga S, Uzawa A, Hirayama R, Matsumoto Y, Sakurai Y, Tanaka H, Tano K, Sanada Y, Suzuki M, Maruhashi A and Ono K
- Journal Title
  
  World J. Oncol.
  
  Volume: 6 Issue: 4 Pages: 398-409
- DOI
  10.14740/wjon941w
- NAID
  120006644056
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00537, KAKENHI-PROJECT-15K09986, KAKENHI-PROJECT-26670556, KAKENHI-PROJECT-15H04295, KAKENHI-PROJECT-24510072
[Journal Article] The effect of oxygen pressure during incubation with a 10B-carrier on 10B uptake capacity of cultured p53 wild-type and mutated tumor cells - Dependency on the p53 status of tumor cells and the type of 10B-carrier.2015
- Author(s)
  Masunaga S, Tatebe H, Nishimura Y, Tano K, Sanada Y, Moriwaki T, Sakurai Y, Tanaka H, Suzuki M, Kondo N, Maruhashi A and Ono K
- Journal Title
  
  Oncol Rep
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510072
[Journal Article] The effect of oxygen pressure during incubation with a 10B-carrier on 10B uptake capacity of cultured p53 wild-type and mutated tumor cells - Dependency on the p53 status of tumor cells and the type of 10B-carrier.2015
- Author(s)
  Masunaga S, Tatebe H, Nishimura Y, Tano K, Sanada Y, Moriwaki T, Sakurai Y, Tanaka H, Suzuki M, Kondo N, Maruhashi A and Ono K.
- Journal Title
  
  Oncology Reports
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670556
[Journal Article] Significance of administering bevacizumab combined with boron neutron capture therapy in terms of local tumor response and lung metastasis2014
- Author(s)
  Masunaga S, Sakurai Y, Tano K, et al. 計11名
- Journal Title
  
  Exp Ther Med
  
  Volume: 8 Issue: 1 Pages: 291-301
- DOI
  10.3892/etm.2014.1704
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300348, KAKENHI-PROJECT-24510072, KAKENHI-PROJECT-26670556
[Journal Article] Significance of Fractionated Administration of Thalidomide Combined With γ-Ray Irradiation in Terms of Local Tumor Response and Lung Metastasis.2014
- Author(s)
  Masunaga S, Sanada Y, Moriwaki T, Tano K, Sakurai Y, Tanaka H, SuzukiM, Kondo N, Narabayashi M, Watanabe T, Nakagawa Y, Maruhashi A and Ono K
- Journal Title
  
  World J Oncol
  
  Volume: 5 Pages: 155-165
- DOI
  10.14740/wjon855w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24510072
[Journal Article] Impact of DNA repair pathways on the cytotoxicity of piperlongumine in chicken DT40 cell-lines.2014
- Author(s)
  Okamoto S, Narita T, Sasanuma H, Takeda S, Masunaga S, Bessho T and Tano K
- Journal Title
  
  Genes Cancer
  
  Volume: 5 Pages: 285-292
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24510072
[Journal Article] The dependency of compound biological effectiveness factors on the type and the concentration of administered neutron capture agents in boron neutron capture therapy2014
- Author(s)
  Masunaga S, Sakurai Y, Tanaka H, Tano K, et al. 計11名
- Journal Title
  
  Springer Plus
  
  Volume: 3 Issue: 1 Pages: 128-128
- DOI
  10.1186/2193-1801-3-128
- NAID
  120005439170
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300348, KAKENHI-PROJECT-24510072, KAKENHI-PROJECT-26670556
[Journal Article] Significance of administering bevacizumab combined with boron neutron capture therapy in terms of local tumor response and lung metastasis.2014
- Author(s)
  Masunaga S, Sakurai Y, Tano K, Tanaka H, Suzuki M, Kondo N, Narabayashi M, Watanabe T, Nakagawa Y, Maruhashi A, Ono K
- Journal Title
  
  Experimental and Therapeutic Medicine
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300348
[Journal Article] Impact of DNA repair pathways on the cytotoxicity of piperlongumine in chicken DT40 cell-lines.2014
- Author(s)
  Okamoto S, Narita T, Sasanuma H, Takeda S, Masunaga S, Bessho T, Tano K.
- Journal Title
  
  Genes & Cancer
  
  Volume: 5 Pages: 285-292
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670556
[Journal Article] Significance of Fractionated Administration of Thalidomide Combined With γ-Ray Irradiation in Terms of Local Tumor Response and Lung Metastasis.2014
- Author(s)
  Masunaga S, Sanada Y, Moriwaki T, Tano K, Sakurai Y, Tnaka H, SuzukiM, Kondo N, Narabayashi M, Watanabe T, Nakagawa Y, Maruhashi A, Ono K.
- Journal Title
  
  World Journal of Oncology
  
  Volume: 5 Pages: 155-165
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670556
[Journal Article] Suppressive effect of ascorbic acid on the mutagenesis induced by the bystander effect through mitochondrial function.2013
- Author(s)
  Kashino G, Tamari Y, Kumagai J, Tano K and Watanabe M
- Journal Title
  
  Free Radic. Res.
  
  Volume: in press Issue: 6-7 Pages: 474-479
- DOI
  10.3109/10715762.2013.791025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510072
[Journal Article] Protective roles of ascorbic acid in oxidative stress induced by depletion of superoxide dismutase in vertebrate cells2013
- Author(s)
  Tamari, Y., Nawata, H., Inoue, E., Yoshimura, A., Yoshii, H., Kashino, G., Seki, M., Enomoto, T., Watanabe, M., and Tano, K
- Journal Title
  
  Free Rad. Res
  
  Volume: 47 Issue: 1 Pages: 1-7
- DOI
  10.3109/10715762.2012.734916
- NAID
  120005398557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370065, KAKENHI-PROJECT-24510072
[Journal Article] Usefulness of daily fractionated administration of wortmannin combined with gamma-ray irradiation in terms of local tumor response and lung metastasis.2013
- Author(s)
  Masunaga S, Sakurai Y, Tanaka H, Suzuki M, Kondo N, Narabayashi M, Tano K, Maruhashi A and Ono K
- Journal Title
  
  World J. Oncol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510072
[Journal Article] Usefulness of daily fractionated administration of wortmannin combined with gamma-ray irradiation in terms of local tumor response and lung metastasis.2013
- Author(s)
  増永慎一郎、櫻井良憲、田中浩基、鈴木実、近藤夏子、楢林正流、田野恵三、丸橋晃、小野公二
- Journal Title
  
  World Journal of Oncology
  
  Volume: 4 Pages: 26-36
- DOI
  10.4021/wjon640w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300348
[Journal Article] Effect of tirapazamine and mild temperature hyperthermia on the recovery from radiation-induced damage in pimonidazole-unlabeled quiescent tumor cell population2013
- Author(s)
  Masunaga S, Sakurai Y, Tanaka H, Suzuki M, Kondo N, Narabayashi M, Tano K, et al. 計9名
- Journal Title
  
  Journal of Cancer Therapy
  
  Volume: 4 Issue: 02 Pages: 521-528
- DOI
  10.4236/jct.2013.42065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300348, KAKENHI-PROJECT-24510072
[Journal Article] Interaction between DNA Polymerase β and BRCA1.2013
- Author(s)
  Masaoka A, Gassman NR, Horton JK, Kedar PS, Witt KL, Hobbs CA, Kissling GE, Tano K, Asagoshi K and Wilson SH
- Journal Title
  
  PLOS ONE
  
  Volume: 8 Issue: 6 Pages: e66801-e66801
- DOI
  10.1371/journal.pone.0066801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510072, KAKENHI-PROJECT-25871149
[Journal Article] FEN1 Functions in Long Patch Base Excision Repair Under Conditions of Oxidative Stress in Vertebrate Cells2010
- Author(s)
  Asagoshi K, Tano K, ChastainII PD, Adachi N, Sonoda E, Kikuchi K, Koyama H, Nagata K, Kaufman DG, Takeda S, Wilson SH, Watanabe M, Swenberg JA, Nakamura J
- Journal Title
  
  Mol.Cancer Res. 8
  
  Pages: 204-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] Usefulness of hexamethylenetetramine as an adjuvant to radiation and cisplatin in the treatment of solid tumors : its independency of p53 status2010
- Author(s)
  Masunaga S, Tano K, Nakamura J, Watanabe M, Kashino G, Takahashi A, Tanaka H, Suzuki M, Ohnishi K, Kinashi Y, Liu Y, Ohnishi T, Ono K
- Journal Title
  
  J.Radiat. Res. 51
  
  Pages: 27-35
- NAID
  10025914038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] Adverse effect of mild temperature hyperthermia combined with hexamethylenetetramine in the treatment of solid tumors : compared with its effect2010
- Author(s)
  Masunaga S, Tano K, Nakamura J, Watanabe M, Kashino G, Suzuki M, Kinashi Y, Ono K
- Journal Title
  
  Exp Therapeut Med 1
  
  Pages: 169-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591493
[Journal Article] Usefulness of combined use of hexamethylenetetramine in the treatment of solid tumors: its independency of p53 status.2010
- Author(s)
  Masunaga S, Tano K, Nakamura J, Watanabe M, Kashino G, Takahashi A, Tanaka H, Suzuki M, Kinashi Y, Ohnishi K, Ohnishi T, Ono K.
- Journal Title
  
  J Radiat Res 51
  
  Pages: 27-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591493
[Journal Article] An alternative mechanism for radioprotection by dimethyl sulfoxide ; possible facilitation of DNA double-strand break repair2010
- Author(s)
  Kashino G, Liu Y, Suzuki M, Masunaga S, Kinashi Y, Ono K, Tano K, Watanabe M
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 51 Pages: 733-740
- NAID
  10026964239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] Usefulness of combined use of hexamethylenetetramine in the treatment of solid tumors : its independency of p53 status.2010
- Author(s)
  Masunaga S, Tano K, Nakamura J, Watanabe M, Kashino G, Takahashi A, Tanaka H, Suzuki M, Kinashi Y, Ohnishi K, Ohnishi T, Ono K
- Journal Title
  
  J Radiat Res 51
  
  Pages: 27-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591493
[Journal Article] An alternative mechanism for radioprotection by dimethyl sulfoxide ; possible facilitation of DNA double-strand break repair2010
- Author(s)
  Kashino G, Liu Y, Suzuki M, Masunaga S, Kinashi Y, Ono K, Tano K, Watanabe M
- Journal Title
  
  J.Radiat. Res. 51
  
  Pages: 733-740
- NAID
  10026964239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] Adverse effect of mild temperature hyperthermia combined with hexamethylene- tetramine in the treatment of solid tumors : compared with its effect combined with tirapazamine.2010
- Author(s)
  Masunaga S, Tano K, Nakamura J, Watanabe M, Kashino G, Suzuki M, Kinashi Y, Ono K.
- Journal Title
  
  Exp Therapeut Med 1
  
  Pages: 169-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591493
[Journal Article] Adverse effect of mild hyperthermia combined with hexyamethylenetetramine compared to its effect combined with tirapazamine in the treatment of solid tumors2010
- Author(s)
  Masunaga S, Tano K, Nakamura J, Watanabe M, Kashino G, Suzuki M, Kinashi Y, Ono K
- Journal Title
  
  Exp.Ther.Med. 1
  
  Pages: 169-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] SOD1 Is Essential for the Viability of DT40 Cells and Nuclear SOD1 Functions as a Guardian of Genomic DNA2010
- Author(s)
  Inoue E, Tano K, Yoshii H, Nakamura J, Tada S, Watanabe M, Seki M, Enomoto T
- Journal Title
  
  Journal of Nucleic Acids
  
  Volume: 2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] Usefulness of hexamethylenetetramine as an adjuvant to radiation and cisplatin in the treatment of solid tumors : its independency of p53 status2010
- Author(s)
  Masunaga S, Tano K, Nakamura J, Watanabe M, Kashino G, Takahashi A, Tanaka H, Suzuki M, Ohnishi K, Kinashi Y, Liu Y, Ohnishi T, Ono K
- Journal Title
  
  J.Radiat.Res. 51
  
  Pages: 27-35
- NAID
  10025914038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] SOD1 Is Essential for the Viability of DT40 Cells and Nuclear SOD1 Functions as a Guardian of Genomic DNA2010
- Author(s)
  Inoue E, Tano K, Yoshii H, Nakamura J, Tada S, Watanabe M, Seki M, Enomoto T
- Journal Title
  
  J.Nucleic Acids 795946
  
  Pages: 1-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] Generation and characterization of cells that can be conditionally depleted of mitochondrial SOD22009
- Author(s)
  S. Takada, E. Inoue, K. Tano, H. Yoshii, T. Abe, A. Yoshimura, M. Akita, S. Tada, M. Watanabe, M. Seki, T. Enomoto
- Journal Title
  
  Biochemical and biophysical research communications 379
  
  Pages: 233-238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] Evalution of the potential of hexamethylenetetramine in combination with gamma-ray irradiation and cisplatin treatment in vivo, compared with tirapazamine.2009
- Author(s)
  Masunaga S, Tano K, Watanabe M, Kashino G, Suzuki M, Kinashi Y, Ono K, Nakamura J
- Journal Title
  
  British Journal of Radiology 82
  
  Pages: 392-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591493
[Journal Article] Evaluation of the potential of hexamethylenetetramine, compared with tirapazamine, as a combined agent with γ-irradiation and cisplatin treatment in vivo2009
- Author(s)
  S. Masunaga, K. Tano, M. Watanabe, G. Kashino, M. Suzuki, Y. Kinashi, K. Ono, J. Nakamura
- Journal Title
  
  British Journal of Radiology
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] Usefulness of hexamethylenetetramine in combination with chemotherapy using free and pegylated liposomal doxorubicin in vivo, referring to the effect on quiescent cells2009
- Author(s)
  S. Masunaga, K. Kono, J. Nakamura, K. Tano, H. Yoshida, M. Watanabe, G. kahino, M. Suzuki, Y. Kinashi, K. Ono
- Journal Title
  
  Oncology Reports
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] Usefulness of hexamethylenetetramine in combination with chemotherapy using free and pegylated liposomal doxorubicin in vivo, referring to the effect on quiescent cells2009
- Author(s)
  Masunaga S, Kono K, Nakamura J, Tano K, Yoshida H, Watanabe M, kahino G, Suzuki M, Kinashi Y, Ono K
- Journal Title
  
  Oncol. Rep. 21
  
  Pages: 1307-1312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] Usefulness of hexamethylenetetramine in combination with chemotherapy using free and pegylated liposomal doxorubicin in vivo, referring to the effect on quiescent cells.2009
- Author(s)
  Masunaga S, Kono K, Nakamura J, Tano K, Yoshida H, Watanabe M, Kashino G, Suzuki M, Kinashi Y, Liu Y, Ono K.
- Journal Title
  
  Oncol Rep 21
  
  Pages: 1307-1312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591493
[Journal Article] Evaluation of the potential of hexamethylene- tetramine in combination with γ-ray irradiation and cisplatin treatment in vivo, compared with tirapazamine.2009
- Author(s)
  Masunaga S, Tano K, Watanabe M, Kashino G, Suzuki M, Kinashi Y, Ono K, Nakamura J.
- Journal Title
  
  Br J Radiol 82
  
  Pages: 392-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591493
[Journal Article] Evaluation of the potential of hexamethylenetetramine in combination with gamma-ray irradiation and cisplatin treatment in vivo, compared with tirapazamine.2009
- Author(s)
  Masunaga S, Tano K, Watanabe M, Kashino G, Suzuki M, Kinashi Y, Ono K, Nakamura J
- Journal Title
  
  Br J Radiol 82
  
  Pages: 392-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591493
[Journal Article] Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS2009
- Author(s)
  Pachkowski BF, Tano K, Afonin V, Elder RH, Takeda S, Watanabe M, Swenberg JA, Nakamura J
- Journal Title
  
  Mut.Res. 671
  
  Pages: 93-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] γ線照射または化学療法時に併用されるヘキサメチレンテトラミンの有用性について2009
- Author(s)
  増永慎一郎、田野恵三、中村純、河野健司、渡邉正巳、鈴木実、菓子野元郎、木梨友子、劉勇、小野公二
- Journal Title
  
  放射線生物研究 44
  
  Pages: 472-482
- NAID
  40016956274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591493
[Journal Article] Evaluation of the potential of hexamethylenetetramine, compared with tirapazamine, as a combined agent with γ-irradiation and cisplatin treatment in vivo2009
- Author(s)
  Masunaga S, Tano K, Watanabe M, Kashino G, Suzuki M, Kinashi Y, Ono K, Nakamura J
- Journal Title
  
  Br.J.Radiol. 82
  
  Pages: 392-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] Generation and characterization of cells that can be conditionally depleted of mitochondrial SOD22009
- Author(s)
  Takada S, Inoue E, Tano K, Yoshii H, Abe T, Yoshimura A, Akita M, Tada S, Watanabe M, Seki M, Enomoto T
- Journal Title
  
  Biochem. Biophys. Res.Commun. 379
  
  Pages: 233-238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510051
[Journal Article] γ線照射または化学療法時に併用されるヘキサメチレンテトラミンの有用性について2009
- Author(s)
  増永慎一郎、田野恵三、中村純、河野健司、渡邉正巳、鈴木実、菓子野元郎、木梨友子、劉勇、小野公二
- Journal Title
  
  放射線生物研究(Radiation Biology Research Communications) 44
  
  Pages: 472-482
- NAID
  40016956274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591493
[Journal Article] Usefulness of hexamethylenetetramine in combination with chemotherapy using free and pegylated liposomal doxorubicin in vivo, referring to the effect on quiescent cells.2009
- Author(s)
  Masunaga S, Kono K, Nakamura J, Tano K, Yoshida H, Watanabe M, Kashino G, Suzuki M, Kinashi Y, Liu Y, Ono K
- Journal Title
  
  Oncol Rep 21
  
  Pages: 1307-1312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591493
[Journal Article] Interplay between DNA polymerases beta and lambda in repair of oxidation DNA damage in chicken DT40 cells.2007
- Author(s)
  Tano, K., Nakamura, J., Asagoshi, K., Arakawa, H., Sonoda, E., Braithwaite, E.K., Prasad, R., Buerstedde, J.M., Takeda, S., Watanabe, M., Wilson, S.H.
- Journal Title
  
  DNA Repair (Amst)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570160
[Journal Article] Interplay between DNA polymerases beta and lambda in repair of oxidation DNA damage in chicken DT40 cells2007
- Author(s)
  Tano, K., Nakamura, J., Asagoshi, K., Arakawa, H., Sonoda, E., Braithwaite, E.K., Prasad, R., Buerstedde, J.M., Takeda, S., Watanabe, M., Wilson, S.H.
- Journal Title
  
  DNA Repair (Amst) (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570160
[Journal Article] Vertebrate POLQ and POLbeta Cooperate In Base Excision Repair of Oxidative DNA Damage.2006
- Author(s)
  Yoshimura, M., Kohzaki, M., Nakamura, J., Asagoshi, K., Sonoda, E., Hou, E., Prasad, R., Wilson, S.H., Tano, K., Yasui, A., Lan, L., Seki, M., Wood, R.D., Arakawa, H., Buerstedde, J.M., Hochegger, et al.
- Journal Title
  
  Mol Cell 24
  
  Pages: 115-125
- Data Source
  KAKENHI-PROJECT-17570160
[Journal Article] Vertebrate POLQ and POLbeta Cooperate in Base Excision Repair of Oxidative DNA Damage2006
- Author(s)
  Yoshimura, M., Kohzaki, M., Nakamura, J., Asagoshi, K., Sonoda, E., Hou, E., Prasad, R., Wilson, S.H., Tano, K., Yasui, A., Lan, L, Seki, M., Wood, R.D., Arakawa, H., Buerstedde, J.M., Hochegger, H., Okada, T., Hiraoka, M., Takeda, S.
- Journal Title
  
  Mol Cell 24
  
  Pages: 115-125
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570160
[Journal Article] Vertebrate POLQ and POLbeta Cooperate in Base Excision Repair of Oxidative DNA Damage.2006
- Author(s)
  Yoshimura, M., Kohzaki, M., Nakamura, J., Asagoshi, K., Sonoda, E., Hou, E., Prasad, R., Wilson, S.H., Tano, K., Yasui, A., Lan, L., Seki, M., Wood, R.D., Arakawa, H., Buerstedde, J.M., Hochegger, et al.
- Journal Title
  
  Mol Cell 24
  
  Pages: 115-125
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570160
[Journal Article] Usefulness of hexamethylenetetramine in combination with chemotherapy using free and pegylated liposomal doxorubicin in vivo, referring to the effect on quiescent cells.
- Author(s)
  Masunaga S, Kono K, Nakamura J, Tano K, Yoshida H, Watanabe M, Kashino G, Suzuki M, Kinashi Y, Liu Y, Ono K.
- Journal Title
  
  Oncology Reports (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591493
[Presentation] azadCによって生じるDNMT1-DPC損傷の修復に関わるSPRTNとプロテオソーム依存的経路の解明2021
- Author(s)
  中野敏彰、津田雅貴、森脇隆仁、笹沼博之、川西優喜、鹿園直哉、井出博、田野恵三
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K11640
[Presentation] Effects Of P53 Status Of Tumor Cells, 10B Delivery Agent Type And Concentration At The Time Of Administration On The Biological Effectiveness For Boron Neutron Capture Therapy.2021
- Author(s)
  Masunaga S, Sanada Y, Tanaka H, Sakurai Y, Tano K, Suzuki M, Ono K
- Organizer
  107th Scientific Assembry and Annual Meeting, Radiological Society of North America
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08171
[Presentation] 休止期腫瘍細胞特性と腫瘍不均一性並びに癌幹細胞性との相互関連性解析成果に基づく従来型ホウ素送達化合物を用いる中性子捕捉療法の治療効果向上の試み2021
- Author(s)
  増永慎一郎、真田悠生、田野恵三、鈴木実、小野公二
- Organizer
  第49回放射線による制癌シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K08171
[Presentation] DNMT1-DNAクロスリンク損傷の修復に関わるSPRTNとプロテオソーム依存的経路の働き2021
- Author(s)
  中野敏彰、津田雅貴、森脇隆仁、笹沼博之、川西優喜、赤松憲、井出博、田野恵三
- Organizer
  日本環境変異原ゲノム学会第50回記念大会
- Data Source
  KAKENHI-PROJECT-18K11640
[Presentation] Usefulness of combination with both continuous administration of hypoxic cytotoxin, tirapazamine and mild temperature hyperthermia in boron neutron capture therapy in terms of local tumor response and lung metastatic potential.2021
- Author(s)
  Masunaga S, Sakurai Y, Tanaka H, Takata T, Suzuki M, Sanada Y, Tano K, Kondo N, Watanabe T, Takeno S, Maruhashi A, Ono K
- Organizer
  19th International Congress on Neutron Capture Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08171
[Presentation] SPRTNはazadCによって導入されたDPCの修復機構に関与している2020
- Author(s)
  中野敏彰, 笹沼博之, 津田雅貴, 廣田耕志, 赤松憲, 川西優喜, 武田俊一, 井出博, 田野恵三
- Organizer
  日本環境変異原学会第49回大会
- Data Source
  KAKENHI-PROJECT-18K11640
[Presentation] 休止期腫瘍細胞特性と癌幹細胞性との関連性解析と癌治療への応用2020
- Author(s)
  増永慎一郎、真田悠生、田野恵三
- Organizer
  第22回菅原・大西記念癌治療増感シンポジウム in 奈良、2020年2月8-9日、奈良
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08171
[Presentation] DNAタンパク質クロスリンク損傷修復におけるSPRTNの関与2020
- Author(s)
  中野敏彰, 笹沼博之, 津田雅貴, 廣田耕志, 赤松憲, 川西優喜, 武田俊一, 井出博, 田野恵三
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K11640
[Presentation] BNCT用化合物に特異的な生物学的効果比(CBE)の10B化合物の種類と投与時濃度への依存性2020
- Author(s)
  増永慎一郎、櫻井良憲、田中浩基、高田卓志、真田悠生、田野恵三、鈴木実、近藤夏子、渡邉翼、武野慧、丸橋晃、小野公二
- Organizer
  日本放射線腫瘍学会第33回学術大会（札幌）
- Data Source
  KAKENHI-PROJECT-19K08171
[Presentation] ホウ素中性子捕捉療法における低酸素細胞毒の連続的投与と低温度温熱療法の同時併用処置の有用性2020
- Author(s)
  増永慎一郎、櫻井良憲、田中浩基、高田卓志、鈴木実、真田悠生、田野恵三、丸橋晃、小野公二
- Organizer
  第79回日本医学放射線学会総会(パシフィコ横浜)
- Data Source
  KAKENHI-PROJECT-19K08171
[Presentation] Usefulness of Combination with Both Continuous Administration of Hypoxic Cytotoxin, Tirapazamine and Mild Temperature Hyperthermia in Boron Neutron Capture Therapy in Terms of Local Tumor Control and Lung Metastatic Potential.2020
- Author(s)
  Masunaga S, Sakurai Y, Tanaka H, Takata T, Sanada Y, Tano K, Suzuki M, Maruhashi A, Ono K.
- Organizer
  106th Scientific Assembry and Annual Meeting, Radiological Society of North America
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08171
[Presentation] The Impact of p53 Status on Radio-sensitivity of Quiescent Tumor Cell Population Irradiated with γ-Rays at Various Dose Rates.2019
- Author(s)
  Masunaga S, Kobayashi J, Tano K, Sanada, Y, Sakurai Y, Tanaka H, Takata T, Suzuki M, Maruhashi A, Ono K.
- Organizer
  the 16th International Congress of Radiation Research (ICRR), August. 25- 29, 2019, Manchester, UK.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08171
[Presentation] ホウ素中性子捕捉療法における連続的低酸素細胞毒投与と低温度温熱処置併用の意義 ―局所腫瘍制御と遠隔肺転移からの解析―2019
- Author(s)
  増永　慎一郎、櫻井　良憲、田中　浩基、高田　卓志、鈴木　実、真田　悠、田野　恵三、渡邉　翼、近藤　夏子、玉利　勇樹、武野　慧、丸橋　晃、小野　公二
- Organizer
  第16回日本中性子捕捉療法学会学術大会（宇治、京都大学キャンパス宇治おうばくプラザ）
- Data Source
  KAKENHI-PROJECT-19K08171
[Presentation] 休止期腫瘍細胞も考慮した局所腫瘍効果と肺転移能に対する腫瘍内酸素状況操作と照射線量率の影響2019
- Author(s)
  増永慎一郎、櫻井良憲、田中浩基、鈴木実、松本孔貴、田野恵三、真田悠生、高田卓志、丸橋晃、小野公二
- Organizer
  第78回日本医学放射線学会総会(パシフィコ横浜)
- Data Source
  KAKENHI-PROJECT-19K08171
[Presentation] How does TDP1 exert in DNA-protein cross- links repair mechanism?2019
- Author(s)
  Toshiaki Nakano, Mahmoud Shoulkamy, Masataka Tsuda, Hiroyuki Sasanuma, Shin-ichiro Masunaga, Shunichi Takeda, Hiroshi Ide, Tadayoshi Bessho, Keizo Tano
- Organizer
  ACEM/JEMS 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11640
[Presentation] Significance of manipulating tumor hypoxia and radiation dose rate in terms of local tumor control and distant lung metastasis.2019
- Author(s)
  Masunaga S, Matsumoto Y, Hirayama R, Tanaka H, Sakurai Y, Suzuki M, Sanada Y, Tano K, Maruhashi A, Ono K.
- Organizer
  the 105th Scientific Assembry and Annual Meeting, Radiological Society of North America, Dec 1-6, 2019, Chicago, IL,USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08171
[Presentation] 中性子捕捉療法における連続的低酸素細胞毒投与と低温度温熱処置併用の意義2019
- Author(s)
  増永慎一郎、櫻井良憲、田中浩基、高田卓志、鈴木実、真田悠生、田野恵三、渡邉翼、近藤夏子、武野慧、玉利勇樹、丸橋晃、小野公二
- Organizer
  日本放射線腫瘍学会第32回学術大会（名古屋）
- Data Source
  KAKENHI-PROJECT-19K08171
[Presentation] Effect of the Change in a Reactor Power on the Response of Murine Solid Tumors in Vivo, Referring to that in Intratumor Quiescent Cells and Its Clinical Significance in Boron Neutron Capture Therapy (BNCT).2018
- Author(s)
  Masunaga S, Sakurai Y, Tanaka H, Takata T, Tano K, Sanada Y, Suzuki M, Maruhashi A, Ono K.
- Organizer
  104th Scientific Assembry and Annual Meeting, Radiological Society of North America
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] 脊椎動物におけるDNA-タンパク質クロスリンク損傷修復へのTDP1, TDP2遺伝子産物の関与2018
- Author(s)
  藤池春奈、Mahmoud Shoulkamy、Amir Salem、津田雅貴、笹沼博之、増永慎一郎、武田俊一、井出博、田野恵三
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K11640
[Presentation] マウス固形腫瘍の挙動に対して原子炉の運転出力変化が及ぼす影響の解析とBoron Neutron Capture Therapy (BNCT)における臨床的意義についての考察2018
- Author(s)
  増永慎一郎、櫻井良憲、田中浩基、高田卓志、田野恵三、真田悠生、鈴木実、近藤夏子、玉利勇樹、丸橋晃、小野公二
- Organizer
  第15回日本中性子捕捉療法学会学術大会（札幌）
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] グルコピラノシルアスコルビン酸の照射後処理による放射線感受性の変化-正常細胞とがん細胞の比較-2018
- Author(s)
  小橋川新子，菓子野元郎，真田悠生，田野恵三，増永慎一郎
- Organizer
  日本放射線影響学会第61回大会(長崎)
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] Disruption of Hif-1alpha enhances the sensitivity to BNCT in murine squamous cell carcinoma.2018
- Author(s)
  Sanada Y, Takata T, Sakurai Y, Tanaka H, Tano K, Masunaga S.
- Organizer
  18th International Congress on Neutron Capture Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] 脊椎動物細胞におけるDNA-タンパク質クロスリンク損傷修復へのTDP1, TDP2遺伝子産物の関与2018
- Author(s)
  藤池春奈、Mahmoud Shoulkamy、Amir Salem、津田雅貴、笹沼博之、増永慎一郎、武田俊一、井出博、田野恵三
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K00537
[Presentation] 酸素化休止期腫瘍細胞の照射後回復に対するメトホルミンの効果-チラパザミン、温熱との比較-2018
- Author(s)
  増永慎一郎、田野恵三、真田悠生、櫻井良憲、田中浩基、鈴木　実、近藤夏子、渡邉　翼、高田卓志、小野公二
- Organizer
  第77回日本医学放射線学会総会(パシフィコ横浜)
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] マウス固形腫瘍の応答に対する原子炉出力変化の影響およびBNCTにおけるその臨床的意義2018
- Author(s)
  増永慎一郎、櫻井良憲、田中浩基、高田卓志、田野恵三、真田悠生、鈴木実、近藤夏子、玉利勇樹、丸橋晃、小野公二
- Organizer
  日本放射線腫瘍学会第31回学術大会（京都）
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] マウス固形腫瘍の挙動に対して原子炉の運転出力変化が及ぼす影響の解析とBoron Neutron Capture Therapy (BNCT)における臨床的意義2018
- Author(s)
  増永慎一郎、櫻井良憲、田中浩基、高田卓志、田野恵三、真田悠生、鈴木実、近藤夏子、玉利勇樹、丸橋晃、小野公二
- Organizer
  第56回日本放射線腫瘍学会生物部会学術大会（東京）
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] 低栄養条件の腫瘍細胞による放射線抵抗性獲得のメカニズム2017
- Author(s)
  真田悠生，田野恵三，増永慎一郎
- Organizer
  日本放射線影響学会第60回大会（千葉）
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] ホウ素中性子捕捉療法における CBE Factor 値の中性子捕捉化合物の種類と投与時における濃度への依存性についての考察2017
- Author(s)
  増永慎一郎、櫻井良憲、田中浩基、田野恵三、真田悠生、鈴木実、近藤夏子、渡邉翼、高田卓志、小野公二
- Organizer
  第14回日本中性子捕捉療法学会学術大会（郡山、福島県）
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] 酸素化休止期腫瘍細胞における放射線照射後回復に対するチラパザミン投与や低温度温熱処置の効果2017
- Author(s)
  増永慎一郎、櫻井良憲、田中浩基、鈴木　実、田野恵三、近藤夏子、真田悠生、渡邉　翼、丸橋　晃、小野公二
- Organizer
  第76回日本医学放射線学会総会
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] 治療生物学的および放射線腫瘍学的視点から見たホウ素中性子捕捉療法の特性2017
- Author(s)
  増永慎一郎、櫻井良憲、鈴木　実、田中浩基、田野恵三、近藤夏子、渡邉　翼、真田悠生、高田卓志、玉利勇樹、丸橋　晃、小野公二
- Organizer
  第19回癌治療増感研究シンポジウム、次世代がん治療を創ろう～高精度放射線・粒子線・創薬・免疫・温熱～
- Place of Presentation
  奈良
- Year and Date
  2017-02-03
- Invited
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] 放射線による細胞老化は遅発性活性酸素種が関与する2017
- Author(s)
  小橋川新子，菓子野元郎，真田悠生，田野恵三，増永慎一郎
- Organizer
  日本放射線影響学会第60回大会（千葉）
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] 酸素化休止期腫瘍細胞の照射後回復に対するメトホルミンの効果-チラパザミン,温熱との比較-2017
- Author(s)
  増永慎一郎、田野恵三、真田悠生、櫻井良憲、田中浩基、鈴木　実、近藤夏子、渡邉　翼、高田卓志、丸橋晃、小野公二
- Organizer
  日本放射線腫瘍学会第30回学術大会（大阪）
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] 放射線による不可逆的老化様細胞増殖停止への遅発性活性酸素種の関与2017
- Author(s)
  小橋川新子、菓子野元郎、真田悠生、田野恵三、増永慎一郎
- Organizer
  第55回日本放射線腫瘍学会生物部会学術大会（名古屋）
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] DNAタンパククロスリンク損傷修復におけるFANC及びTDP1遺伝子産物の関与2017
- Author(s)
  藤池春奈, Mahmoud Shoulkamy, Amir Salem, 笹沼博之, 高田穣, 武田俊一, 増永慎一郎, 井出博, 田野恵三
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K00537
[Presentation] DNAタンパククロスリンク損傷修復におけるFANC及びTDP1遺伝子産物の関与2017
- Author(s)
  藤池春奈, Mahmoud Shoulkamy, Amir Salem, 笹沼博之, 高田穣, 武田俊一, 増永慎一郎, 井出博, 田野恵三
- Organizer
  日本環境変異原学会第46回大会
- Data Source
  KAKENHI-PROJECT-15K00537
[Presentation] ピモニダゾール非標識休止期腫瘍細胞分画での照射後回復に対するメトフィルミンの効果-ティラパザミンや低温度温熱処置との比較-2017
- Author(s)
  増永慎一郎、田野恵三、真田悠生、鈴木実、小野公二
- Organizer
  日本ハイパーサーミア学会第34回学術大会(京都)
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] Radiosensitivity of Pimonidazole -Unlabeled Intratumor Quiescent Cells to Gamma-Rays, Accelerated Carbon Ion Beams and Boron Neutron Capture Reaction (BNCR).2017
- Author(s)
  Shin-ichiro Masunaga, Yoshinori Sakurai, Hiroki Tanaka, Roichi Hirayama, Yoshitaka Matsumoto, Akiko Uzawa, Keizo Tano, Yu Sanada, Minoru Suzuki, Natsuko Kondo, Takushi Takata, Tsubasa Watanabe, Yuki Tamari, Akira Maruhashi, Koji Ono.
- Organizer
  9th Young Researchers' BNCT Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] Radiosensitivity and Capacity to Recover from Radiation-Induced Damage in Pimonidazole-Unlabeled Oxygenated Intratumor Quiescent Cells Depend on p53 Status of Tumor Cells.2016
- Author(s)
  Masunaga S, Tano K, Sanada Y, Sakurai Y, Tanaka H, Suzuki M, Maruhashi A, Ono K
- Organizer
  the 58th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO)
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] 低グルコースにおいて致死作用をもつメトフォルミンとフェンフォルミンの作用機序の解析2016
- Author(s)
  角田圭，森脇隆仁，藤池春奈，津田雅貴，笹沼博之，高田穣，井出博，武田俊一，増永慎一郎，田野恵三
- Organizer
  日本環境変異原学会第45回大会
- Place of Presentation
  つくば国際会議場（茨城県、つくば市）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-15K00537
[Presentation] Anti-diabetic biguanide drugs, metformin and phenformin have genotoxicity upon glucose deprivation in chicken DT40 cells2016
- Author(s)
  Kadoda K, Moriwaki T, Fujiike H, Tsuda M, Sasanuma H, Takata M, Takeda S, Masunaga S, Tano K
- Organizer
  The 10th 3R Symposium
- Place of Presentation
  Hotel Ichihata, Matsue, Japan
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00537
[Presentation] The effect of fractionated administration of thalidomide at γ-ray irradiation on tumor response and lung metastasis.2016
- Author(s)
  S. Masunaga, K. Tano, Y. Sanada, Y. Sakurai, H. Tanaka, M. Suzuki, N. Kondo, M. Narabayashi, T. Watanabe, Y. Nakagawa, A. Maruhashi, and K. Ono.
- Organizer
  The International Conference on Translational Research in Radiation Oncology - Physics for Health in Europe 2016
- Place of Presentation
  International Center for Conference in Geneva, Geneva, Switzerland
- Year and Date
  2016-02-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] The effect of fractionated administration of thalidomide at γ-ray irradiation on tumor response and lung metastasis.2016
- Author(s)
  S. Masunaga, K. Tano, Y. Sanada, Y. Sakurai, H. Tanaka, M. Suzuki, N. Kondo, M. Narabayashi, T. Watanabe, Y. Nakagawa, A. Maruhashi, and K. Ono.
- Organizer
  International Conference on Translational Research in Radiation Oncology -- Physics for Health in Europe 2016
- Place of Presentation
  International Center for Conference in Geneva, Geneva, Switzerland
- Year and Date
  2016-02-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] 抗腫瘍効果から見た中性子捕捉療法の治療生物学的解釈2016
- Author(s)
  増永慎一郎、櫻井良憲、鈴木　実、田中浩基、丸橋　晃、田野恵三、真田悠生、近藤夏子、渡邉　翼、高田卓志、小野公二
- Organizer
  第45回放射線による制癌シンポジウム
- Place of Presentation
  難波、大阪
- Year and Date
  2016-07-15
- Invited
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] Effect of oxygen pressure during incubation with a 10B-carrier on 10B uptake capacity of cultured p53 wild－type and mutated tumor cells with reference to dependency on p53 status of tumor cells and types of 10B-carriers.2016
- Author(s)
  Masunaga S, Tatebe H, Nishimura Y, Tano K, Sanada Y, Sakurai Y, Tanaka H, Suzuki M, Kondo N, Watanabe T, Takata T, Fujimoto N, Maruhashi A, Ono K.
- Organizer
  the 17th International Congress on Neutron Capture Therapy
- Place of Presentation
  Columbia, Missouri, USA
- Year and Date
  2016-10-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] DT40ノックアウト細胞パネルを用いたグルコース枯渇下で細胞致死性作用を持つBiguanide薬剤の作用機序の解析2016
- Author(s)
  角田圭，森脇隆仁，藤池春奈，津田雅貴，笹沼博之，高田穣，武田俊一，増永慎一郎，田野恵三
- Organizer
  日本放射線影響学会第59回大会
- Place of Presentation
  ＪＭＳアステールプラザ（広島県、広島市）
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15K00537
[Presentation] Significance of fractionated administrations of thalidomide combined with gamma-ray irradiation from the viewpoint of local tumor response and lung metastasis.2016
- Author(s)
  Masunaga S, Sanada Y, Moriwaki T, Tano K, Sakurai Y, Tanaka H, Suzuki M,, Narabayashi M, Watanabe T, and Ono K.
- Organizer
  the 2016 Annual Meeting of the American Roentgen Ray Society
- Place of Presentation
  Washington DC, USA
- Year and Date
  2016-04-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] 10B化合物との共培養時における酸素分圧が及ぼす培養細胞の10B取込能への影響2016
- Author(s)
  増永慎一郎、建部仁志、西村恭昌、田野恵三、真田悠生、櫻井良憲、田中浩基、鈴木実、近藤夏子、丸橋晃、小野公二
- Organizer
  日本放射線腫瘍学会第29回学術大会
- Place of Presentation
  京都
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] 腫瘍細胞のメトフォルミン感受性についてHIF-1α欠損が及ぼす効果2016
- Author(s)
  真田悠生，田野恵三，増永慎一郎
- Organizer
  第18回癌治療増感研究シンポジウム、変貌する放射線治療法～物理・化学・生物学増感法のリミックスと免疫学のコラボレーション～
- Place of Presentation
  奈良県文化会館、（奈良県、奈良市）
- Year and Date
  2016-02-05
- Invited
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] DT40ノックアウト細胞を用いたBiguanide系薬剤Metforminによるグルコース枯渇下細胞致死作用の解析2016
- Author(s)
  角田圭，森脇隆仁，藤池春奈，津田雅貴，笹沼博之，高田穣，井出博，武田俊一，増永慎一郎，田野恵三
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K00537
[Presentation] The effect of oxygen pressure during incubation with a 10B-carrier on 10B uptake capacity of cultured p53 wild-type and mutated tumor cells.2015
- Author(s)
  Masunaga S, Tatebe H, Nishimura Y, Tano K, Sanada Y, Moriwaki T, Sakurai Y, TanakaH, Suzuki M, Maruhashi A,Ono K.
- Organizer
  The 15th International Congress of Radiation Research (ICRR)
- Place of Presentation
  Kyoto International Conference Center, （京都府、京都市）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] Characteristics of differential cytotoxicity profile of tirapazamine between normoxia and hypoxia.2015
- Author(s)
  Moriwaki T, Okamoto S, Sasanuma H, Nagasawa H, Takeda S, Masunaga S and Tano K
- Organizer
  15th International Congress of Radiation Research (ICRR)
- Place of Presentation
  Kyoto International Conference Center, Kyoto,Japan
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] DT40ノックアウト細胞パネルを用いたグルコース枯渇下で細胞致死作用を持つBiguanide２種の作用機序の解析2015
- Author(s)
  角田圭，森脇隆仁，津田雅貴，笹沼博之，武田俊一，増永慎一郎，田野恵三
- Organizer
  日本環境変異原学会第４４回大会
- Place of Presentation
  九州大学馬出キャンパス　コラボ・ステーションⅠ・Ⅱ（福岡県、福岡市）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15K00537
[Presentation] Characteristics of differential cytotoxicity profile of tirapazamine between normoxia and hypoxia.2015
- Author(s)
  Moriwaki T, Okamoto S, Sasanuma H, Nagasawa H, Takeda S, Masunaga S and Tano K
- Organizer
  15th International Congress of Radiation Research (ICRR)
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00537
[Presentation] 局所腫瘍効果と肺転移抑制能から見たγ線照射時における分割サリドマイド投与併用の意義2015
- Author(s)
  増永慎一郎、真田悠生、森脇隆宏、田野恵三、櫻井良憲、田中浩基、鈴木　実、楢林正流、渡邉　翼、小野公二
- Organizer
  第74回日本医学放射線学会総会
- Place of Presentation
  パシフィコ横浜、（神奈川県、横浜市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] Characteristics of Differential Cytotoxicity Profile of Tirapazamine between Normoxia and Hypoxia.2015
- Author(s)
  Moriwaki T, Okamoto S, Sasanuma H, Nagasawa H, Takeda S, Masunaga S, Tano K.
- Organizer
  The 15th International Congress of Radiation Research (ICRR)
- Place of Presentation
  Kyoto International Conference Center, （京都府、京都市）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] DT40細胞のDNA修復欠損細胞パネルを用いた酸素濃度に依存したチラパラザミンのDNA損傷誘発と細胞致死効果の解析2015
- Author(s)
  森脇隆仁，岡本紗季，笹沼博之，永澤秀子，武田俊一，増永慎一郎，田野恵三
- Organizer
  第68回日本酸化ストレス学会学術集会
- Place of Presentation
  かごしま県民交流センター（鹿児島県、鹿児島市）
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15K00537
[Presentation] DT40細胞のDNA修復欠損細胞パネルを用いた酸素濃度に依存したチラパラザミンのDNA損傷誘発と細胞致死効果の解析2015
- Author(s)
  森脇隆仁，岡本紗季，笹沼博之，永澤秀子，武田俊一，増永慎一郎，田野恵三
- Organizer
  第68回日本酸化ストレス学会学術集会
- Place of Presentation
  鹿児島県民交流センター、（鹿児島県、鹿児島市）
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] The effect of oxygen pressure during incubation with a 10B-carrier on 10B uptake capacity of cultured p53 wild-type and mutated tumor cells.2015
- Author(s)
  Masunaga S, Tatebe H, Nishimura Y, Tano K, Sanada Y, Moriwaki T, Sakurai Y, TanakaH, Suzuki M, Maruhashi A,Ono K.
- Organizer
  The 15th International Congress of Radiation Research (ICRR)
- Place of Presentation
  国立京都国際会館（京都府、京都市）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] DT40ノックアウト細胞パネルを用いたグルコース枯渇下で細胞致死作用を持つBiguanide２種の作用機序の解析2015
- Author(s)
  角田圭，森脇隆仁，津田雅貴，笹沼博之，武田俊一，増永慎一郎，田野恵三
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  九州大学馬出キャンパス　コラボ・ステーションⅠ・Ⅱ、（福岡県、福岡市）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] DT40ノックアウト細胞パネルを用いたグルコース枯渇下で細胞致死作用を持つBiguanide２種の作用機序の解析2015
- Author(s)
  角田圭，森脇隆仁，津田雅貴，笹沼博之，武田俊一，増永慎一郎，田野恵三
- Organizer
  日本環境変異原学会第４４回大会
- Place of Presentation
  九州大学馬出キャンパス　コラボ・ステーションⅠ・Ⅱ（福岡県、福岡市）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] Characteristics of the response of intratumor quiescent (Q) cells to irradiation, referring to recruitment from Q to proliferating state.2015
- Author(s)
  Masunaga S, Tano K, Sanada Y, Moriwaki T, Ono K.
- Organizer
  The 15th International Congress of Radiation Research (ICRR)
- Place of Presentation
  国立京都国際会館（京都府、京都市）
- Year and Date
  2015-05-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] Characteristics of Differential Cytotoxicity Profile of Tirapazamine between Normoxia and Hypoxia.2015
- Author(s)
  Moriwaki T, Okamoto S, Sasanuma H, Nagasawa H, Takeda S, Masunaga S, Tano K.
- Organizer
  The 15th International Congress of Radiation Research (ICRR)
- Place of Presentation
  国立京都国際会館（京都府、京都市）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] Characteristics of the response of intratumor quiescent (Q) cells to irradiation, referring to recruitment from Q to proliferating state.2015
- Author(s)
  Masunaga S, Tano K, Sanada Y, Moriwaki T, Ono K.
- Organizer
  The 15th International Congress of Radiation Research (ICRR)
- Place of Presentation
  Kyoto International Conference Center, （京都府、京都市）
- Year and Date
  2015-05-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] Effect of Hif-1α knockout on sensitivity to metformin in SCCVII murine carcinoma cells2015
- Author(s)
  Yu Sanada, Keizo Tano, Shin-ichiro Masunaga
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド、（兵庫県、神戸市）
- Year and Date
  2015-10-01
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] Usefulness of fractionated administrations of thalidomide combined with gamma-ray irradiation in terms of local tumor response and lung metastasis.2015
- Author(s)
  Masunaga S, Sanada Y, Tano K, Sakurai Y, Tanaka H, Suzuki M, Narabayashi M, Watanabe T, Takata T, Maruhashi A, Ono K.
- Organizer
  日本放射線腫瘍学会第28回学術大会
- Place of Presentation
  ベイシア文化ホール、（群馬県、前橋市）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15H04295
[Presentation] DT40細胞のDNA修復欠損細胞パネルを用いた酸素濃度に依存したチラパラザミンのDNA損傷誘発と細胞致死効果の解析2015
- Author(s)
  森脇隆仁，岡本紗季，笹沼博之，永澤秀子，武田俊一，増永慎一郎，田野恵三
- Organizer
  第68回日本酸化ストレス学会学術集会
- Place of Presentation
  かごしま県民交流センター（鹿児島県、鹿児島市）
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] 治療抵抗性休止期腫瘍細胞の特性から見た放射線増感2014
- Author(s)
  増永慎一郎、田野恵三、小野公二
- Organizer
  第20回癌治療増感研究会
- Place of Presentation
  高知県民文化ホール,. 高知
- Year and Date
  2014-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] 局所腫瘍制御と肺転移抑制能から見たγ線照射時における分割ウォルトマニン投与併用の有用性2014
- Author(s)
  増永慎一郎、田野恵三、櫻井良憲、田中浩基、鈴木実、近藤夏子、楢林正流、渡辺翼、丸橋晃、小野公二
- Organizer
  第73回日本医学放射線学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-23300348
[Presentation] 局所腫瘍効果と肺転移抑制能から見た分割ウォルトマニン投与併用γ線照射の有用性2013
- Author(s)
  増永慎一郎、田野恵三、櫻井良憲、田中浩基、鈴木実、近藤夏子、楢林正流、渡邉翼、丸橋晃、小野公二
- Organizer
  日本放射線腫瘍学会第26回学術大会
- Place of Presentation
  ホテル青森、リンクステーションホール青森
- Data Source
  KAKENHI-PROJECT-23300348
[Presentation] ピモニダゾール非標識酸素化休止期腫瘍細胞分画における放射線損傷からの回復をウォルトマニンは効率よく抑制する2013
- Author(s)
  増永慎一郎、田野恵三、櫻井良憲、田中浩基、鈴木実、近藤夏子、楢林正流、渡邉翼、木梨友子、丸橋晃、小野公二
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  ホテルクラウンパレス青森、青森
- Data Source
  KAKENHI-PROJECT-23300348
[Presentation] The dependency of compound biological effectiveness factors on the type and concentration of administered neutron capture agents in BNCT2013
- Author(s)
  Masunaga S, Tano K., et al
- Organizer
  At the 7th Young Researchers Boron Neutron Capture Therapy Meeting
- Place of Presentation
  Granada, Spain
- Data Source
  KAKENHI-PROJECT-23300348
[Presentation] The dependency of compound biological effectiveness factors on the type and concentration of administered neutron capture agents in BNCT.2013
- Author(s)
  Masunaga S, Tano K, Sakurai Y, Tanaka H, Suzuki M, Kondo N, Narabayashi M, Watanabe T, Maruhashi A, Ono K.
- Organizer
  The 7th Young Researchers Boron Neutron Capture Therapy Meeting
- Place of Presentation
  Granada, Spain
- Data Source
  KAKENHI-PROJECT-23300348
[Presentation] Significance of daily fractionated administration of wortmannin combined with gamma-ray irradiation in terms of local tumor response and lung metastatic potential.2013
- Author(s)
  Masunaga S, Tano K, Sakurai Y, Tanaka H, Suzuki M, Kondo N, Narabayashi M, Watanabe T, Maruhashi A, Ono K
- Organizer
  the 55th Annual Meeting of The American Society for Therapeutic Radiology and Oncology (ASTRO).
- Place of Presentation
  Atlanta, Georgia, USA.
- Data Source
  KAKENHI-PROJECT-23300348
[Presentation] 休止期腫瘍細胞の挙動に及ぼす分割照射の影響について2013
- Author(s)
  増永慎一郎、田野恵三、小野公二
- Organizer
  次世代がん治療推進専門家養成プラン、シンポジウム～癌治療抵抗性機構とその克服～(Part II)、放射線治療の潮流　‐Hypofractionationの基礎と臨床－　（東京）
- Place of Presentation
  東京医科歯科大学、東京
- Invited
- Data Source
  KAKENHI-PROJECT-23300348
[Presentation] Significance of daily fractionated administration of wortmannin combined with γ-ray irradiation in terms of local tumor response and lung metastatic potential2013
- Author(s)
  Masunaga S, Tano K., et al
- Organizer
  At the 55th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO)
- Place of Presentation
  Atlanta, Georgia, USA
- Data Source
  KAKENHI-PROJECT-23300348
[Presentation] 細胞内酸化レベルの恒常性維持に関わるPRDX1の機能解析2013
- Author(s)
  田野恵三，吉村明，玉利勇樹，菓子野元郎，関政幸，榎本武美，渡邉正己
- Organizer
  第66回日本酸化ストレス学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] 中性子捕捉療法（BNCT）における腫瘍内低酸素の意義2013
- Author(s)
  増永慎一郎、田野恵三、櫻井良憲、田中浩基、鈴木実、近藤夏子、楢林正流、渡邉翼、丸橋晃、小野公二
- Organizer
  第42回放射線による制癌シンポジウム、シンポジウムI：低酸素状態と放射線感受性　（仙台）
- Place of Presentation
  艮陵会館（東北大学医学部キャンパス前）、仙台
- Invited
- Data Source
  KAKENHI-PROJECT-23300348
[Presentation] ピモニダゾール非標識酸素化休止期腫瘍細胞分画における放射線損傷からの回復に対するティラパザミン処置，低温度温熱処置の影響2013
- Author(s)
  増永慎一郎、田野恵三、鈴木実、近藤夏子、楢林正流、渡邉翼、小野公二
- Organizer
  日本ハイパーサーミア学会第30回大会　シンポジウム「再発、転移に対する温熱生理」
- Place of Presentation
  横浜シンポジア（横浜）
- Invited
- Data Source
  KAKENHI-PROJECT-23300348
[Presentation] Either SOD1, SOD2 or PRDX1 is required for normal cell growth in vertebrate cells2011
- Author(s)
  Tano K, Inoue E, Yoshimura A, Seki M, Enomoto T, Watanabe M
- Organizer
  The 2011 GRC on Oxidative Stress and Disease
- Place of Presentation
  Ventura, CA, USA
- Year and Date
  2011-03-16
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] Either SOD1, SOD2 or PRDX1 is required for normal cell growth in vertebrate cells2011
- Author(s)
  田野恵三, 井上絵里, 吉村明,関政幸, 榎本武美, 渡邉正己
- Organizer
  The 2011 GRC on Oxidative Stress and Disease
- Place of Presentation
  Ventura, CA, USA.
- Year and Date
  2011-03-16
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] 細胞内局在性を異にする内在性スーパーオキシドによる細胞増殖阻害へのアスコルビン酸及び低酸素の効果2010
- Author(s)
  田野恵三、井上絵里、縄田寿克、菓子野元郎、関政幸、榎本武美、渡邉正己
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] X線誘発微小核形成はDNA二重鎖切断に起因しない2010
- Author(s)
  岡田卓也、菓子野元郎、田野恵三、渡邉正己
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] OD1枯渇細胞とPRDX1枯渇細胞の抗酸化剤に対する挙動の違い2010
- Author(s)
  樋口優人、井上絵里、田野恵三、吉村明、渡邉正己、榎本武美、関政幸
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] X線誘発微小核形成はDNA 二重鎖切断に起因しない2010
- Author(s)
  岡田卓也, 菓子野元郎, 田野恵三, 渡邉正己
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] SOD1枯渇細胞とPRDX1枯渇細胞の抗酸化剤に対する挙動の違い2010
- Author(s)
  樋口優人, 井上絵里, 田野恵三, 吉村明, 渡邉正己, 榎本武美, 関政幸
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] 染色体3倍体化におけるがん形質の獲得2010
- Author(s)
  縄田寿克、菓子野元郎、田野恵三,法村俊之、渡邉正己
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] 染色体3倍体化おけるがん形質の獲得2010
- Author(s)
  縄田寿克, 菓子野元郎, 田野恵三, 法村俊之, 渡邉正己
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] 発がん過程における染色体異数化の役割2009
- Author(s)
  縄田寿克、田野恵三、久郷裕之、押村光雄、渡邉正己
- Organizer
  日本放射線影響学会52回大会
- Place of Presentation
  広島
- Year and Date
  2009-11-11
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] Nuclear superoxide may trigger spontaneous sister chromatid exchanges2009
- Author(s)
  井上絵里, 田野恵三, 吉居華子, 高田隼也, 吉村明, 縄田寿克, 中村純, 多田周右, 渡邉正己, 関政幸, 榎本武美
- Organizer
  日本分子生物学会32回年回
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] ビタミンCはX線誘発DNA二重鎖生成を抑制しない2009
- Author(s)
  岡田卓也、菓子野元郎、田野恵三、渡邉正己
- Organizer
  日本放射線影響学会52回大会
- Place of Presentation
  広島
- Year and Date
  2009-11-11
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] Nuclear superoxide may trigger spontaneous sister chromatid exchanges2009
- Author(s)
  井上絵里、田野恵三、吉居華子、高田隼也、吉村明、縄田寿克、中村純、多田周右、渡邉正己、関政幸、榎本武美
- Organizer
  日本分子生物学会32回年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] メラノジェネシスにおける紫外線誘発酸化ストレスの影響2009
- Author(s)
  西浦英樹, 田野恵三, 渡邉正己
- Organizer
  日本放射線影響学会52回大会
- Place of Presentation
  広島
- Year and Date
  2009-11-11
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] 内在性スーパーオキシドによる細胞増殖阻害及び染色体不安定化に対するアスコルビン酸の抑制効果2009
- Author(s)
  田野恵三、井上絵里、吉居華子、縄田寿克、関政幸、榎本武美、渡邉正己
- Organizer
  日本放射線影響学会52回大会
- Place of Presentation
  広島
- Year and Date
  2009-11-11
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation]2008
- Author(s)
  増永慎一郎、田野恵三、中村純、渡邉正巳、菓子野元郎、鈴木実、劉勇、木梨友子、小野公二
- Organizer
  第10回関西ハイパーサーミア研究会、第19回高温度療法臨床研究会合同研究会
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2008-07-26
- Data Source
  KAKENHI-PROJECT-20591493
[Presentation] トリ細胞におけるミスマッチ修復遺伝子の紫外線損傷修復に対する機能2008
- Author(s)
  田野恵三, 森俊雄, 中村純, 荒川央, 武田俊一, 渡邉正巳
- Organizer
  放射線影響学会第51回大会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2008-11-20
- Data Source
  KAKENHI-PROJECT-20510051
[Presentation] 放射線照射やシスプラチン投与時の併用薬剤としてのヘキサメチレンテトラミンの有用性2008
- Author(s)
  増永慎一郎、田野恵三、渡邉正巳、菓子野元郎、鈴木実、小野公二、木梨友子、中村純
- Organizer
  日本放射線腫瘍学会第21回学術大会
- Place of Presentation
  札幌パークホテル
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-20591493
[Presentation] 放射線照射、シスプラチン投与時の併用薬剤としてのヘキサメチレンテトラミン(HMTA)の有用性と低温度温熱処置(MTH)併用の意義について2008
- Author(s)
  増永慎一郎, 田野恵三, 中村純, 渡邉正巳, 菓子野元郎, 鈴木実, 劉勇, 木梨友子, 小野公二
- Organizer
  第10回関西ハイパーサーミア研究会、第19回高温度療法臨床研究会合同研究会
- Place of Presentation
  大阪国際交流センター2階第C, D会議室
- Year and Date
  2008-07-26
- Data Source
  KAKENHI-PROJECT-20591493
[Presentation] 活性酸素種による細胞内恒常性維持に関わるPRDX1の機能解析
- Author(s)
  田野恵三，吉村明，玉利勇樹，菓子野元郎，関政幸，榎本武美，渡邉正己
- Organizer
  日本放射線影響学会第55回大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] Tirapazamine induces genome instability via formation of aberrant DNA ends in hypoxia-dependent
- Author(s)
  Moriwaki T, Okamoto S, Sasanuma H，Nagasawa H, Takeda S, Masunaga S and Tano K
- Organizer
  日本分子生物学会第37回年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] Significance of Administering Bevacizumab Combined with Boron Neutron Capture Therapy in terms of Local Tumor Control and Lung Metastatic Potential.
- Author(s)
  Masunaga S, Sakurai Y, Tano K, Tanaka H, Suzuki M, Kondo N, NarabayashiM, Watanabe T, Nakagawa Y, Maruhashi A, Ono K.
- Organizer
  the 56th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO)
- Place of Presentation
  Moscone center, San Francisco, USA
- Year and Date
  2014-09-14 – 2014-09-17
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] DT40 ノックアウトパネルを用いた低酸素毒チラパザミンが生じる損傷の解析
- Author(s)
  森脇隆仁，岡本紗季，笹沼博之，永澤秀子，武田俊一，増永慎一郎，田野恵三
- Organizer
  日本環境変異原学会第43回大会
- Place of Presentation
  一橋大学（東京都）
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] Induction of double strand breaks and chromosomal aberrations by piperlongumine.
- Author(s)
  Saki Okamoto, Tadayoshi Bessho, Hiroyuki Sasanuma, Shunichi Takeda, Shin-ichiro Masunaga, Keizo Tano
- Organizer
  17th Biennial Meeting of Society for Free Radical Research International (SFRRI2014)
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] The depletion of antioxidant enzymes resulted differential oxidative stress and induced cell death independent of DNA damage.
- Author(s)
  Moriwaki T, Okamoto S, Yoshimura A，Inoue E, Seki M, Masunaga S and Tano K
- Organizer
  Gordon Research Conference on Genomic Instability
- Place of Presentation
  Hong Kong, China
- Year and Date
  2014-07-06 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] Characteristics of the response of intratumor quiescent (Q) cells to irradiation, referring to recruitment from Q to proliferating state.
- Author(s)
  Masunaga S, Tano K, Sanada Y, Moriwaki T and Ono K
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  国立京都国際会館（京都市）
- Year and Date
  2015-05-25 – 2015-05-29
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] SOD1、PRDX1 の欠損は DNA 損傷を介さない細胞死を引き起こす
- Author(s)
  森脇隆仁，岡本紗季，関政幸，榎本武美，増永慎一郎，田野恵三
- Organizer
  第67回日本酸化ストレス学会学術集会
- Place of Presentation
  同志社大学（京都市）
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] Piperlongumineが誘発する二本鎖DNA切断と染色体断裂
- Author(s)
  岡本紗季、別所忠昌、笹沼博之、武田俊一、増永慎一郎、田野恵三
- Organizer
  日本環境変異原学会第42回大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] 治療生物学的解析から見た硼素中性子捕捉療法(BNCT)の特性
- Author(s)
  増永慎一郎、田野恵三、櫻井良憲、田中浩基、鈴木実、近藤夏子、楢林正流、仲川洋介、渡邉翼、真田悠生、森脇隆仁、丸橋晃、小野公二
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  かごしま県民センター、鹿児島
- Year and Date
  2014-10-01 – 2014-10-03
- Invited
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] Impact of DNA repair pathways on the cytotoxicity of piperlongumine in vertebrata cells.
- Author(s)
  Okamoto S, Narita T, Sasanuma H，Takeda S，Masunaga S，Bessho T and Tano K
- Organizer
  Gordon Research Conference on Genomic Instability
- Place of Presentation
  Hong Kong, China
- Year and Date
  2014-07-06 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] Characteristics of differential cytotoxicity profile of tirapazamine between normoxia and hypoxia.
- Author(s)
  Moriwaki T, Okamoto S, Sasanuma H, Nagasawa H, Takeda S, Masunaga S and Tano K
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  国立京都国際会館（京都市）
- Year and Date
  2015-05-25 – 2015-05-29
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] Significance of Combined Treatment with Bevacizumab in Boron Neutron Capture Therapy in Terms of Local Tumor Response and Lung Metastasis.
- Author(s)
  Masunaga S, Sakurai Y, Tano K, Tanaka H, Suzuki M, Kondo N, Narabayashi3 M, Watanabe T, Nakagawa Y, Maruhashi A and Ono K
- Organizer
  16th International Congress on Neutron Capture Therapy
- Place of Presentation
  Helsinki, Finland
- Year and Date
  2014-06-14 – 2014-06-19
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] The dependency of CBE factors on the concentration of administered neutron capture agents in BNCT.
- Author(s)
  Masunaga S, Sakurai Y, Tanaka H, Tano K, Suzuki M, Kondo N, Narabayashi M, Watanabe T, Nakagawa Y, Maruhashi A and Ono K.
- Organizer
  The 2nd KURRI International Workshop on BNCT - Basic Science and Technology for BNCT -
- Place of Presentation
  Kyodai Rakuyu Kaikan, Kyoto, Japan
- Year and Date
  2014-12-09 – 2014-12-10
- Invited
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] Effect of bevacizumab combined with boron neutron capture therapy on local tumor response and lung metastasis.
- Author(s)
  Masunaga S, Sakurai Y, Tanaka H, Tano K, Suzuki M, Kondo N, Narabayashi M, Watanabe T, Maruhashi A, Ono K.
- Organizer
  the 6th Asian Congress of Hyperthermic Oncology (ACHO) & the 31st Japanese Congress of Thermal Medivine (JCTM)
- Place of Presentation
  AOSSA, Fukui, Japan
- Year and Date
  2014-09-05 – 2014-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] 抗酸化酵素PRDX1の細胞内恒常性維持に関わる機能の解析
- Author(s)
  田野恵三，吉村明，玉利勇樹，菓子野元郎，関政幸，榎本武美，渡邉正己
- Organizer
  日本環境変異原学会第41回大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] piperlongumineによる二本鎖DNA切断の誘発と染色体断裂
- Author(s)
  岡本紗季、別所忠昌、笹沼博之、武田俊一、増永慎一郎、田野恵三
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24510072
[Presentation] Significance of Combined Treatment with Bevacizumab in Boron Neutron Capture Therapy in Terms of Local Tumor Response and Lung Metastasis.
- Author(s)
  Masunaga S, Sakurai Y, Tano,Ｋ Tanaka H, Suzuki M, Kondo N, Narabayashi M, Watanabe T, Nakagawa Y, Maruhashi A and Ono K.
- Organizer
  the 16th International Congress on Neutron Capture Therapy
- Place of Presentation
  Poerssitalo, Helsinki, Finland
- Year and Date
  2014-06-14 – 2014-06-19
- Data Source
  KAKENHI-PROJECT-26670556
[Presentation] PiperlongumineによるDNA二本鎖切断の誘発と相同組み換えの抑制
- Author(s)
  岡本紗季，別所忠昌，笹沼博之，武田俊一，増永慎一郎，田野恵三
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  かごしま県民交流センター（鹿児島市）
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-24510072

1. MASUNAGA Shinichiro (80238914)

# of Collaborated Projects: 11 results

# of Collaborated Products: 138 results
2. UTSUMI Hiroshi (20025646)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. YASUHIRA Shinji (90311729)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. NAGASAWA Hideko (90207994)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
5. 真田悠生 (50738656)

# of Collaborated Projects: 3 results

# of Collaborated Products: 37 results
6. KASHINO Genro (00437287)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
7. SONODA Eiichiro (50281093)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. AKABOSHI Mitsuhiko (00027418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKADA Jitsuya (10115868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KINASHI Yuko (80252534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ONO Koji (90122407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KAWAI Kenichi (30110761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAKIMOTO Koichi (00115875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TACHIBANA Akira (20188262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SAKURAI Yoshinori (20273534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 宮武伸一 (90209916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 川西優喜 (70332963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
18. 光藤健司 (70303641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TAKEDA Shun-ichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
20. 笹沼博之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 榎本武美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 永沢秀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 小林純也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tano Keizo 田野 恵三

TANO Keizo 田野 恵三

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Biguanide系薬剤Metforminの腫瘍内環境特性による細胞致死と抗腫瘍免疫誘導の解析Principal Investigator

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Analyses of selective cytotoxicity of the anti-diabetic biguanide drug, Metformin, in solid tumor specific microenvironmentPrincipal Investigator

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Analysis of neoplastic cell-specific fatal effects with reactive oxygen species abnormality derived from compound from plant species, piperlonguminePrincipal Investigator

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Biological impact Mechanism maintenance and assessment of biological impact of intracellular reactive oxygen species produced by normal physiological reactionPrincipal Investigator

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Characterization and biological assessment of DNA-Protein crosslink repair in vertebrate cellsPrincipal Investigator

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Tano Keizo 田野恵三

TANO Keizo 田野恵三