FUJII Junichi 藤井順逸

… Alternative Names

Researcher Number	00222258
Other IDs
Affiliation (Current)	2019: 山形大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2018: 山形大学, 大学院医学系研究科, 教授 2016: 山形大学, 大学院医学研究科, 教授 2015: 山形大学, 医学(系)研究科(研究院), 教授 2014: 山形大学, 大学院医学研究科, 教授 2012: 山形大学, 医学(系)研究科(研究院), 教授 … More
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Pathological medical chemistry / General medical chemistry / Basic Section 49010:Pathological biochemistry-related / General medical chemistry / Structural biochemistry Except Principal Investigator Pathological medical chemistry / Biological Sciences / Pathological medical chemistry / General medical chemistry … More
Keywords	Principal Investigator 一酸化窒素 / グルタチオン / アポトーシス / SOD1 / glutathione / 精子形成 / システイン / トランススルフィレーション経路 / Growth factor / Baculovirus … More Except Principal Investigator グルタチオン / 活性酸素 / ペルオキシレドキシン / 一酸化窒素 / グリケーション / Reactive oxygen species / Mn-SOD / Glycation / 血管内皮細胞 / アポトーシス / 酸化ストレス / プロテオミクス / SOD / TNF / 筋萎縮性側索硬化症 / システイン / 糖タンパク質 / gamma-glutamyl transpeptidase / FALS / IL-1 / xCT / γ-glutamyl transpeptidase / 肝炎 / フリーラジカル / オートクリン活性 / アポリポプロテインE / 減数分裂 / drug metabolism / 3-Deoxyglucosone / プロテインキナ-ゼーC / 3-デオキシグルコソン / 形質転換増殖因子 / 抗酸化剤 / apoptosis / 癌 / 合成ペプチド / ロヴァスタチン / 増殖因子 / ウィルソン病モデル動物 / glutathione / γ-グルタミルトランスペプチダーゼ / ジャクスタクリン活性 / Amyotrophic lateral sclerosis / 腫瘍マーカー / 卵成熟 / グルタチオンペルオキシダーゼ / Ｆｅｒｒｏｐｔｏｓｉｓ / Hydroxy radical / Growth factor / アポプロテインE / 過酸化物 / ベルオキシレドキシン / p21 / LEC rat / Free radical / endothelial cells / Antioxidants / 発癌 / r-グルタミルトランスペプチダーゼ / ヒドロキシラジカル / 抗酸化酵素 / 糖尿病性合併症 / β2インテグリン / MnーSOD / 糖転移酵素 / バキュロウィルス / 卵巣癌 / Prx4 / 炎症細胞 / 肝薬物代謝酵素 / 糖化反応 / DNA fragmentation / 好中球 / nitric oxide / glutathine / Mn-スーパーオキサイドディスムターゼ / 肝癌 / 発生障害 / 培養系 / apolipoprotein E / セレン / site-directed mutagenesis / IVM / 肝細胞分画 / ヘパリン結合性EGF様増殖因子 / reactive oxygen species / 上皮性卵巣癌 / Apoptosis / ferroptosis / LFA1 / シスチン輸送体 / 卵母細胞 / 低酸素再酸素化 / glutathione peroxidase / Mutation / DNA低メチル化 / heparin binding EGF-like growth factor / CD9 / チオレドキシン / vascular smooth muscle / hepatoma / DNAマイクロアレイ / 部位特異的変異 / 糖尿病 / マクロファージ / Diabetic complications / 小胞体 / Diabetes / redox balance / 異数性 / メチル基代謝 / Carcinogenesis / Signal transduction / 2-オキソアルデヒド化合物 / Cu, Zn-SOD / シグナル伝達 / choline-deficient diet / 紡錘体形成チェックポイント / ILー1 / DNA damage / Sーアデノシルメチオニン合成酵素 / カルボ-ルエステル / Proteomics / Wilson's disease / ｘＣＴ / 糖鎖遺伝子 / DNA microarray / ヘパリン結合性上皮増殖因子 / 蛋白質の酸化的折畳み / NO (peroxynitrite) / 肝炎モデル / Hydroxyl radical / Hypoxia reperfusion / フェントン反応 / glycation / Cytochrome P450 / 紫外線 / オフタルミン酸 / スーパーオキシドディスムターゼ / 悪性化 / NO合成酵素 / 血管平滑筋 / 抗酸化物質 / growth factor / 活性酸素種 / LECラット / HB-EGF / 肝癌自然発症 / spontaneous hepatitis / TGF-beta / 老化 / 分子シミュレーション / DNA hypomethylation / EGF受容体 / diabetes / ウイルソン病 / セルロプラスミン / メチオニン代謝異常 / バキュロウイルス / Cu,Zn-SOD / 体外成熟,IVM / 炎症発癌 Less

一酸化窒素(NO)合成酵素由来と外因性NOによるスーパーオキシドの毒性軽減の証明Principal InvestigatorOngoing
- Principal Investigator
  
  藤井順逸
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Yamagata University
Elucidation of induction of ferroptosis and inhibition of tumor growth caused by suppressing cystine transporter xCT
- Principal Investigator
  
  Kobayashi Sho
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity start-up
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yamagata University
Roles of transsulfuration-mediated cysteine uptake and hydrogen sulfide in liverPrincipal Investigator
- Principal Investigator
  
  Fujii Junichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yamagata University
Studies on the physiological role of Prx4 in oxidative protein folding
- Principal Investigator
  
  Kurahashi Toshihiro
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
  General medical chemistry
- Research Institution
  Kyoto Prefectural University of Medicine
  Yamagata University
Investigation into the cause of oocyte aneuploidy using antioxidant capasity deficient mice and application to advanced IVM methods
- Principal Investigator
  
  KIMURA Naoko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied animal science
- Research Institution
  Yamagata University
Redox regulation of endoplasmic reticulum stress and signals by reactive oxygen speciesPrincipal Investigator
- Principal Investigator
  
  FUJII Junichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Yamagata University
炎症発癌を標的としたロヴァスタチンの結合構造情報に基づく化合物探索
- Principal Investigator
  
  岡田太
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yamagata University
炎症発がんを標的としたペプチド治療法の開発
- Principal Investigator
  
  OKADA Futoshi
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yamagata University
Hypoxia-to-reoxygenation condition as one of the internal carcinogenic factors of common cancers
- Principal Investigator
  
  OKADA Futoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Yamagata University
Analyses of Roles of SOD1 in Protection against Photoaging and Carcinogenesis Using SOD1-deficient MicePrincipal Investigator
- Principal Investigator
  
  FUJII Junichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yamagata University
Investigation on a role of Prx4 in spermatogenesis by gene knockout approachPrincipal Investigator
- Principal Investigator
  
  FUJII Junichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Yamagata University School of Medicine
皮膚癌を誘発する紫外線からの新規抗酸化酵素ペルオキシレドキシンによる防御機構
- Principal Investigator
  
  葛巻丈二朗
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Yamagata University
Redox regulation by glutathione and the roles of reactive oxygen and nitrogen species
- Principal Investigator
  
  TANIGUCHI Naoyuki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
Development of a method for early diagnosis of diabetic of complications by detecting glycation reaction intermediates.Principal Investigator
- Principal Investigator
  
  FUJII Junichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
Remodeling of regulation of cell growth by glycogene and its application.Principal Investigator
- Principal Investigator
  
  FUJII Junichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka University
一酸化窒素の細胞毒性とグルタチオンペルオキシダーゼ不活性化機構Principal Investigator
- Principal Investigator
  
  藤井順逸
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
Regulation of Cellular Activity by Reactive Oxygen
- Principal Investigator
  
  TANIGUCHI Naoyuki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka University
Mechanisms of apoptosis of endothelial and vascular smooth muscle cells by reactive oxygen species -Relationship with the initiation of arteriosclerosis-
- Principal Investigator
  
  SUZUKI Keiichiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
血管系における一酸化窒素(NO)産生とNO合成酵素の活性調節機構に関する研究Principal Investigator
- Principal Investigator
  
  藤井順逸
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
Significance of sugar moiery of recombinant glycoproteins
- Principal Investigator
  
  TANIGUCHI Naoyuki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Osaka University
ジャクスタクリン機構を介した細胞膜結合型細胞増殖因子と癌細胞増殖
- Principal Investigator
  
  東山繁樹
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Cu,Zn-スーパーオキサイドディスムターゼの変異と筋萎縮性側索硬化症Principal Investigator
- Principal Investigator
  
  藤井順逸
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
Site-specific fragmentation of superoxide dismutase and DNA damage
- Principal Investigator
  
  TANIGUCHI Naoyuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
腫瘍マーカーとしてのMn-スーパーオキサイドディスムターゼの癌化による発現機構Principal Investigator
- Principal Investigator
  
  藤井順逸, 谷口直之
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
腫瘍マ-カ-としてのMnース-パ-オキサイドディスムタ-ゼの癌化による発現機構
- Principal Investigator
  
  TANIGUCHI Naoyuki
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Correlation between the spontaneous hepatitis and hepatoma and the disorder of methyl group metabolism in LEC rats
- Principal Investigator
  
  SUGIYAMA Toshihiro
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Akita University
  Osaka University

All 2017 2016 2015 2014 2013 2012 2011 2010 2006 2005 2001 2000 1998 Other

All Journal Article Presentation Book

[Book] Ascorbic Acid: Properties, Synthesis and Applications2016
- Author(s)
  Junichi Fujii, Takujiro Homma, Sho Kobayashi
- Total Pages
  285
- Publisher
  Nova Science Publishers, Inc
- Data Source
  KAKENHI-PROJECT-15K08294
[Book] Superoxide Dismutase (SOD): Sources, Therapeutic Uses and Health Benefits2016
- Author(s)
  Takujiro Homma, Junichi Fujii
- Total Pages
  197
- Publisher
  Nova Science Publishers, Inc
- Data Source
  KAKENHI-PROJECT-15K08294
[Book] Antithetical Roles of Reactive Oxygen Species in Mammalian Reproduction r In Handbook of System Biology of Free Radicals and Anti-oxidants2013
- Author(s)
  Junichi Fujii, Satoshi Tsunoda, and Naoko Kimura
- Publisher
  Springer-Verlag(I. Larher ed)(in press)
- Data Source
  KAKENHI-PROJECT-22590262
[Book] Handbook of System Biology of Free Radicals and Anti-oxidants2013
- Author(s)
  Junichi Fujii
- Total Pages
  17
- Publisher
  Antithetical Roles of Reactive Oxygen Species in Mammalian Reproduction
- Data Source
  KAKENHI-PROJECT-22590262
[Book] Handbook of System Biology of Free Radicals and Anti-oxidants2012
- Author(s)
  Junichi Fujii, Satoshi Tsunoda, Naoko Kimura
- Publisher
  Antithetical Roles of Reactive Oxygen Species in Mammalian Reproduction(印刷中)
- Data Source
  KAKENHI-PROJECT-22590262
[Book] Antithetical Roles of Reactive Oxygen Species in Mammalian Reproduction r In Handbook of System Biology of Free Radicals and Anti-oxidants. (I. Larher ed)2012
- Author(s)
  Junichi Fujii, Satoshi Tsunoda, and Naoko Kimura.
- Total Pages
  17
- Publisher
  Springer-Verlag, Germany, in press (2012)
- Data Source
  KAKENHI-PROJECT-24580405
[Book] Male and Female Infertility:Genetic Causes, Hormonal Treatments and Health Effects2010
- Author(s)
  Fujii, Junichi
- Total Pages
  22
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-22590262
[Book] Medical Biochemistry 2^<nd> ed2005
- Author(s)
 Junichi Fujii
- Total Pages
 12
- Publisher
 Mosby
- Description
 「研究成果報告書概要(和文)」より
- Data Source
 KAKENHI-PROJECT-16590238
[Book] Medical Biochemistry 2^<nd> ed2005
- Author(s)
 J Fujii
- Total Pages
 12
- Publisher
 M.H.Dominiczak and J.W.Baynes
- Data Source
 KAKENHI-PROJECT-16590238
[Journal Article] Decreased reproductive performance in xCT-knockout male mice2017
- Author(s)
  Hamashima, S., Homma, T., Kobayashi, S., Ishii, N., Kurahashi, T., Watanabe, R., Kimura, N., Sato, H., and Fujii, J.
- Journal Title
  
  Free Radic Res
  
  Volume: 51 Pages: 851-860
- DOI
  10.1080/10715762.2017.1388504
- Open Access / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01829, KAKENHI-PROJECT-17K01365, KAKENHI-PROJECT-17K07158, KAKENHI-PROJECT-17K08977, KAKENHI-PROJECT-16H06648, KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
[Journal Article] Mice in the early stage of liver steatosis caused by a high fat diet are resistant to thioacetamide-induced hepatotoxicity and oxidative stress2017
- Author(s)
  Lee Jaeyong、Homma Takujiro、Fujii Junichi
- Journal Title
  
  Toxicology Letters
  
  Volume: 277 Pages: 92-103
- DOI
  10.1016/j.toxlet.2017.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
[Journal Article] Increased ophthalmic acid production is supported by amino acid catabolism under fasting conditions in mice2017
- Author(s)
  Sho Kobayashi, Jaeyong Lee, Toshifumi Takao, Junichi Fujii.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 491 Pages: 649-655
- DOI
  10.1016/j.bbrc.2017.07.149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06648, KAKENHI-PROJECT-15K08294
[Journal Article] The viability of primary hepatocytes is maintained under a low cysteine-glutathione redox state with a marked elevation in ophthalmic acid production.2017
- Author(s)
  Lee, J., Kang, E. S., Kobayashi, S., Homma, T., Sato, H., Seo, H. G., and Fujii, J.
- Journal Title
  
  Exp Cell Res
  
  Volume: 361 Pages: 178-191
- DOI
  10.1016/j.yexcr.2017.10.017
- Open Access / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01829, KAKENHI-PROJECT-17K07158, KAKENHI-PROJECT-17K08977, KAKENHI-PROJECT-16H06648, KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
[Journal Article] Protective role of testis-specific peroxiredoxin 4 against cellular oxidative stress2017
- Author(s)
  Eisuke Tasaki, Shotaro Matsumoto, Hisashi Tada, Toshihiro Kurahashi, Xuhong Zhang, Junichi Fujii, Toshihiko Utsumi, Yoshihito Iuchi
- Journal Title
  
  J. Clin. Biochem. Nutr.
  
  Volume: 60(3) Issue: 3 Pages: 156-161
- DOI
  10.3164/jcbn.16-96
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26660113, KAKENHI-PROJECT-17K01365, KAKENHI-PROJECT-17K07758, KAKENHI-PROJECT-15K08294
[Journal Article] A high-fat diet temporarily renders Sod1-deficient mice resistant to an oxidative insult2017
- Author(s)
  Junitsu Ito, Naoki Ishii, Ryusuke Akihara, Jaeyong Lee, Toshihiro Kurahashi, Takujiro Homma, Ryo Kawasaki, Junichi Fujii
- Journal Title
  
  J Nutr Biochem
  
  Volume: 40 Pages: 44-52
- DOI
  10.1016/j.jnutbio.2016.10.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16592, KAKENHI-PROJECT-15K08294
[Journal Article] xCT deficiency aggravates acetaminophen-induced hepatotoxicity under inhibition of the transsulfuration pathway.2017
- Author(s)
  Eun Sil Kang, Jaeyong Lee, Takujiro Homma, Toshihiro Kurahashi, Sho Kobayashi, Atsunori Nabeshima, Sohsuke Yamada, Han GeuK Seo, Satoshi Miyata, Hideyo Sato, Junichi Fujii
- Journal Title
  
  Free Radic. Res.
  
  Volume: 51 Pages: 80-90
- DOI
  10.1080/10715762.2017.1282157
- Open Access / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06648, KAKENHI-PROJECT-16K16592, KAKENHI-PROJECT-16K01829, KAKENHI-PROJECT-17K07158, KAKENHI-PROJECT-17K08977, KAKENHI-PROJECT-15K08294
[Journal Article] Ascorbic acid prevents acetaminophen-induced hepatotoxicity in mice by ameliorating glutathione recovery and autophagy2017
- Author(s)
  Kurahashi T, Lee J, Nabeshima A, Homma T, Kang ES, Saito Y, Yamada S, Nakayama T, Yamada K, Miyata S, Fujii J.
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 604 Pages: 1319-1333
- DOI
  10.1016/j.abb.2016.06.004
- Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870075, KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
[Journal Article] Heightened aggressive behavior in mice deficient in aldo-keto reductase 1a (Akr1a)2017
- Author(s)
  Takujiro Homma, Ryusuke Akihara, Satoshi Okano, Mototada Shichiri, Yasukazu Yoshida, Ken-ichi Yamada, Satoshi Miyata, Osamu Nakajima, Junichi Fujii
- Journal Title
  
  Behav Brain Res
  
  Volume: 319 Pages: 219-224
- DOI
  10.1016/j.bbr.2016.11.038
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16592, KAKENHI-PROJECT-15K08294
[Journal Article] Protective role of testis-specific peroxiredoxin 4 against cellular oxidative stress.2017
- Author(s)
  Eisuke Tasaka, Shotaro Matsumoto, Hisashi Tada, Toshihiro Kurahashi, Xuhong Zhang, Junichi Fujii, Toshihiko Utsumi, Yoshihito Iuchi
- Journal Title
  
  J Clin Biochem Nutr
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294
[Journal Article] The SOD1 transgene expressed in erythroid cells alleviates fatal phenotype in congenic NZB/NZW-F1 mice.2016
- Author(s)
  Noriyuki Otsuki, Tasuku Konno, Toshihiro Kurahashi, Saori Suzuki, Jaeyong Lee, Futoshi Okada, Yoshihito Iuchi, Takujiro Homma, Junichi Fujii
- Journal Title
  
  Free Radic Res
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294
[Journal Article] Ablation of aldehyde reductase aggravates carbon tetrachloride-induced acute hepatic injury involving oxidative stress and endoplasmic reticulum stress.2016
- Author(s)
  Ryusuke Akihara, Takujiro Homma, Jaeyong Lee, Ken-ichi Yamada, Satoshi Miyata, Junichi Fujii
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 478 Pages: 765-771
- DOI
  10.1016/j.bbrc.2016.08.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
[Journal Article] Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease2016
- Author(s)
  Aya Nawata, Hirotsugu Noguchi, Yuichi Mazaki, Toshihiro Kurahashi, Atsunori Nabeshima, Ke-Yong Wang, Satoshi Kimura, Hidetaka Uramoto, Kimitoshi Kohno, Hatsumi Taniguchi, Yoshiya Tanaka, Junichi Fujii, Yasuyuki Sasaguri Toshiyuki Nakayama, and Sohsuke Yamada.
- Journal Title
  
  PLoS One
  
  Volume: e0152549
- DOI
  10.1371/journal.pone.0152549
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-25440051, KAKENHI-PROJECT-25870075, KAKENHI-PROJECT-16K08750
[Journal Article] Heat stress promotes the down-regulation of IRE1α in cells: An atypical modulation of the UPR pathway.2016
- Author(s)
  Takujiro Homma, Junichi Fujii
- Journal Title
  
  Experimental Cell Research
  
  Volume: 349 Pages: 128-138
- DOI
  10.1016/j.yexcr.2016.10.006
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
[Journal Article] The SOD1 transgene expressed in erythroid cells alleviates fatal phenotype in congenic NZB/NZW-F1 mice2016
- Author(s)
  Otsuki N, Konno T, Kurahashi T, Suzuki S, Lee J, Okada F, Iuchi Y, Homma T, Fujii J.
- Journal Title
  
  Free Radical Research
  
  Volume: 50 Pages: 793-800
- DOI
  10.1080/10715762.2016.1178388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870075, KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
[Journal Article] Trichloroethylene exposure aggravates behavioral abnormalities in mice that are deficient in superoxide dismutase2016
- Author(s)
  Otsuki N, Homma T, Fujiwara H, Kaneko K, Hozumi Y, Shichiri M, Takashima M, Ito J, Konno T, Kurahashi T, Yoshida Y, Goto K, Fujii S, Fujii J.
- Journal Title
  
  Regulatory Toxicology and Pharmacology
  
  Volume: 79 Pages: 83-90
- DOI
  10.1016/j.yrtph.2016.05.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870075, KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
[Journal Article] Characteristics of Skeletal Muscle Fibers of SOD1 Knockout Mice2016
- Author(s)
  Hiroshi Nagahisa, Kazuma Okabe, Yoshihito Iuchi, Junichi Fujii, Hirofumi Miyata.
- Journal Title
  
  Oxidative Medicine and Cellular Longevity
  
  Volume: 9345970 Pages: 9345970-9345970
- DOI
  10.1155/2016/9345970
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-15K12681
[Journal Article] Oxidative stress as a potential causal factor for autoimmune hemolytic anemia and systemic lupus erythematosus2015
- Author(s)
  Junichi Fujii, Toshihiro Kurahashi, Tasuku Konno, Takujiro Homma, Yoshihito Iuchi
- Journal Title
  
  World J Nephrol
  
  Volume: 4 Pages: 213-222
- DOI
  10.5527/wjn.v4.i2.213
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294
[Journal Article] Roles of Antioxidative Enzymes in Wound Healing2015
- Author(s)
  Toshihiro Kurahashi, Junichi Fujii.
- Journal Title
  
  J Dev Biol
  
  Volume: 3 Pages: 57-70
- DOI
  10.3390/jdb3020057
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294
[Journal Article] Physiological and Pathological Views of Prdx4.2015
- Author(s)
  Junichi Fujii, Yoshitaka Ikeda, Toshihiro Kurahashi, Takujiro Homma
- Journal Title
  
  Free Radic. Biol. Med
  
  Volume: 83 Pages: 373-379
- DOI
  10.1016/j.freeradbiomed.2015.01.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294
[Journal Article] Application of glutathione as anti-oxidative and anti-aging drug.2015
- Author(s)
  Takujiro Homma, Junichi Fujii
- Journal Title
  
  Curr Drug Metab
  
  Volume: 16 Pages: 560-571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294
[Journal Article] Oxidative stress triggers lipid droplet accumulation in primary cultured hepatocytes by activating fatty acid synthesis2015
- Author(s)
  Jaeyong Lee, Takujiro Homma, Toshihiro Kurahashi, Eun Sil Kang, andJunichi Fujii.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 464 Pages: 229-235
- DOI
  10.1016/j.bbrc.2015.06.121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-25870075
[Journal Article] SOD1 deficiency decreases proteasomal function, leading to the accumulation of ubiquitinated proteins in erythrocytes2015
- Author(s)
  Takujiro Homma, Toshihiro Kurahashi, Jaeyong Lee, Eun Sil Kang and Junichi Fujii
- Journal Title
  
  Arch Biochem Biophys
  
  Volume: 583 Pages: 65-72
- DOI
  10.1016/j.abb.2015.07.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-25870075
[Journal Article] Cystathionine is a novel substrate ofcystine/glutamate transporter: implications forimmune function.2015
- Author(s)
  Kobayashi, S., Sato, M., Kasakoshi, T., Tsutsui, T., Sugimoto, M., Osaki, M., Okada, F., Igarashi, K., Hiratake, J., Homma, T., Conrad, M., Fujii, J., Soga, T., Bannai, S., Sato, H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 290 Pages: 8778-8788
- DOI
  10.1074/jbc.m114.625053
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22134007, KAKENHI-PROJECT-24500967, KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-26460472, KAKENHI-PROJECT-26462860
[Journal Article] SOD1 deficiency induces the systemic hyperoxidation of peroxiredoxin in the mouse2015
- Author(s)
  Takujiro Homma, Satoshi Okano, Jaeyong Lee, Junitsu Ito, Noriyuki Otsuki, Toshihiro Kurahashi, Eun Sil Kang, Osamu Nakajima, and Junichi Fujii
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 463 Pages: 1040-1046
- DOI
  10.1016/j.bbrc.2015.06.055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-25870075
[Journal Article] An SOD1 deficiency enhances lipid droplet accumulation in the fasted mouse liver by aborting lipophagy2015
- Author(s)
  Toshihiro Kurahashi, Shinji Hamashima, Takaya Shirato, Jaeyong Lee, Takujiro Homma, Eun Sil Kang, Junichi Fujii.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 467 Pages: 866-871
- DOI
  10.1016/j.bbrc.2015.10.052
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-25870075
[Journal Article] Ascorbic acid reverses the prolonged anesthetic action of pentobarbital in Akr1a-knockoutmice2014
- Author(s)
  Junitsu Ito a,Noriyuki Otsuki a, Xuhong Zhang a, Tasuku Konno a, Toshihiro Kurahashi a,Motoko Takahashi b, Mayumi YamaKen-ichi Yamada d, Satoshi Miyata e, Junichi Fujiito c,YutaMatsuoka d,
- Journal Title
  
  Life Sciences
  
  Volume: 95 Pages: 1-8
- DOI
  10.1016/j.lfs.2013.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870075
[Journal Article] Kidney fi brosis is independent of the amount of ascorbic acid in mice with unilateral ureteral obstruction2014
- Author(s)
  Nishida H, Kurahashi T, Saito Y, Otsuki N, Kwon M, Ohtake H H, Yamakawa M, Yamada K, Miyata S, Tomita Y, Fujiia J
- Journal Title
  
  Free Radical Research
  
  Volume: 48 Pages: 1115-1124
- DOI
  10.3109/10715762.2014.915031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460451, KAKENHI-PROJECT-25870075
[Journal Article] Oxidative stress and redox regulation of gametogenesis, fertilization, and embryonic development2014
- Author(s)
  Tsunoda S, K, Kimura N and Fujii J
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 13 Pages: 71-79
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580405
[Journal Article] Reductive detoxification of acrolein as a potential role for aldehyde reductase (AKR1A) in mammals.2014
- Author(s)
  Toshihiro Kurahashi a, Myoungsu Kwona, Takujiro Hommaa, Yuka Saito a, Jaeyong Lee a, Motoko Takahashi b, Ken-ichi Yamadac, Satoshi Miyata d, Junichi Fujii
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 452 Pages: 136-141
- DOI
  10.1016/j.bbrc.2014.08.072
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25870075, KAKENHI-PROJECT-26440058
[Journal Article] Differential responses of SOD1-deficient mouse embryonic fibroblasts to oxygen concentrations.2013
- Author(s)
  Tsunoda S, Kibe N, Kurahashi T, and Fujii J.
- Journal Title
  
  Arch. Biochem. Biophys.
  
  Volume: 537 Pages: 5-11
- DOI
  10.1016/j.abb.2013.06.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870075
[Journal Article] 細胞内外で多様な機能を発揮するレドックス分子・ぺルオキシレドキシン-42012
- Author(s)
  藤井順逸
- Journal Title
  
  日本応用酵素協会誌
  
  Volume: 47 Pages: 19-27
- Data Source
  KAKENHI-PROJECT-22590262
[Journal Article] Endoplasmic reticulum thiol oxidase deficiency leads to ascorbic acid depletion and noncanonical scurvy in mice2012
- Author(s)
  Ester Zito, Henning Gram Hansen, Giles S. H. Yeo, Junichi Fujii, and David Ron.
- Journal Title
  
  Mol Cell
  
  Volume: 48 Pages: 39-51
- DOI
  10.1016/j.molcel.2012.08.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590262
[Journal Article] A malfunction in the triglyceride transfer from the intracellular lipid pool to the apoB in the enterocytes of SOD1-deficient mice2012
- Author(s)
  Kurahashi Toshihiro, Konno Tasuku, Otsuki Noriyuki, Kwon Myoungsu, Tsunoda Satoshi, Ito Junitsu, Fujii Junichi
- Journal Title
  
  FEBS Lett
  
  Volume: 586 Pages: 4289-4295
- DOI
  10.1016/j.febslet.2012.09.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J56123, KAKENHI-PROJECT-22590262
[Journal Article] Impaired fertilizing ability of Sod1-deficient mouse sperm during in-vitro fertilization2012
- Author(s)
  Tsunoda S, Kawano N, Miyado K, Kimura N, Fujii J.
- Journal Title
  
  Biology of Reproduction
  
  Volume: 87 Pages: 106-106
- DOI
  10.1007/978-3-642-30018-9_108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580405
[Journal Article] 細胞増殖に関わるリン酸化・脱リン酸化の制御における活性酸素種のシグナル伝達分子としての役割2012
- Author(s)
  藤井順逸
- Journal Title
  
  Vitamemebrane
  
  Volume: 12 Pages: 1-9
- Data Source
  KAKENHI-PROJECT-22590262
[Journal Article] Measurement of Peroxiredoxin-4 in Rat Tissues and Implication of Its Serum Levels as a Potential Marker for Hepatic Disease2012
- Author(s)
  Ritsu Ito, Motoko Takahashi, Hideyuki Ihara, Hiroki Tsukamoto, Junichi Fujii, Yoshitaka Ikeda
- Journal Title
  
  Mol Med Report
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590262
[Journal Article] 酸化ストレスと女性生殖機能-活性酸素のもつ細胞内シグナルとしての役割2012
- Author(s)
  藤井順逸
- Journal Title
  
  Hormone Frontier in Gynecology
  
  Volume: 19 Pages: 143-147
- Data Source
  KAKENHI-PROJECT-22590262
[Journal Article] Impaired fertilizing ability of Sod1-deficient mouse sperm during in-vitro fertilization2012
- Author(s)
  Tsunoda Satoshi, Kawano Natsuko, Miyado Kenji, Kim ura Naoko, Fujii Junichi.
- Journal Title
  
  Biol Reprod
  
  Volume: 87 Pages: 121-121
- DOI
  10.1095/biolreprod.112.102129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J56123, KAKENHI-PLANNED-21112006, KAKENHI-PROJECT-22590262, KAKENHI-PROJECT-23659788
[Journal Article] Physiological Relevance of Antioxid/Redox Genes; Learning from Genetically Modified Animals Guest Editor: Junichi Fujii Introduction to serial reviews: physiological relevance of antioxid/redox genes; learning from genetically modified animals2011
- Author(s)
  Junichi Fujii
- Journal Title
  
  J. Clin. Biochem. Nutr.
  
  Volume: 49 Issue: 2 Pages: 69-69
- DOI
  10.3164/jcbn.10-138SRInt
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590262
[Journal Article] Physiological Relevance of Antioxid/Redox Genes; Learning from Genetically Modified Animals Guest Editor: Junichi Fujii Unveiling the roles of the glutathione redox system in vivo by analyzing genetically modified mice2011
- Author(s)
 Junichi Fujii, Jun-itsu Ito, Xuhong Zhang, Toshihiro Kurahashi
- Journal Title
 
 J. Clin. Biochem. Nutr.
 
 Volume: 49 Issue: 2 Pages: 70-78
- DOI
 10.3164/jcbn.10-138SR
- ISSN
 0912-0009, 1880-5086
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-22590262
[Journal Article] Different consequences of the reactions with hydrogen peroxide and t-butyl hydro peroxide in the hyperoxidative inactivation of rat peroxiredoxin-42011
- Author(s)
  Yoshitaka Ikeda, Miyako Nakano, Hideyuki Ihara, Ritsu Ito, Naoyuki Taniguchi, Junichi Fujii
- Journal Title
  
  J Biochem
  
  Volume: 149 Pages: 443-453
- DOI
  10.1093/jb/mvq156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590262
[Journal Article] Redox regulation of spermatogenic process and fertilisation2011
- Author(s)
  Junichi Fujii, Satoshi Tsunoda
- Journal Title
  
  Asian J Androl
  
  Volume: VOL.13 Pages: 420-423
- DOI
  10.1038/aja.2011.10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J56123, KAKENHI-PROJECT-22590262
[Journal Article] Peroxiredoxin-controlled G-CSF signalling at the endoplasmic reticulum-early end osome interface2011
- Author(s)
  Karishma Palande, Onno Roovers, Judith Gits, Carola Verwijmeren, Yoshihito Iuchi, Junichi Fujii, Benjamin G Neel, Robert Karisch, Jan Tavernier, and Ivo P Touw
- Journal Title
  
  J Cell Sci
  
  Volume: 124 Pages: 3695-3705
- DOI
  10.1242/jcs.089656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590262
[Journal Article] Identification and characterization of an alternatively transcribed form of peroxir edoxin IV that is specifically expressed in spermatids of the postpubertal mouse testis2011
- Author(s)
  Sun Hee Yim, Yoo-Jin Kim, Sue Young Oh, Junichi Fujii, Yan Zhang, Vadim N. Gladyshev, and Sue Goo Rhee
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 39002-39012
- DOI
  10.1074/jbc.m111.257220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590262
[Journal Article]2011
- Author(s)
  Fujii, Junichi
- Journal Title
  
  J CIin Biochem Nutr
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590262
[Journal Article] Development of a quantitative bioassay to assess preventive compounds against inflammation-based carcinogenesis2011
- Author(s)
  Kunishige Onuma, Yuka Suenaga, Ryuta Sakaki, Satoshi Yoshitome, Yu Sato, Satomi Ogawara, Saori Suzuki, Mitsuhiro Kuramitsu, Hidekatsu Yokoyama, Akira Murakami, Junichi Hamada, Garth L Nicolson, Masanobu Kobayashi, Junichi Fujii, Futoshi Okada
- Journal Title
  
  Nitric Oxide
  
  Volume: 25 Pages: 183-194
- DOI
  10.1016/j.niox.2011.02.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590262, KAKENHI-PROJECT-23590461
[Journal Article] Identification of a lipid peroxidation product as the source of oxidation-specific epitopes recognized by anti-DNA autoantibodies2010
- Author(s)
  Otaki, N., Chikazawa, M., Nagae, R., Shimozu, Y., Shibata, T., Ito, S., Takasaki, Y., Fujii, J., and Uchida, K.
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 33834-33842
- DOI
  10.1074/jbc.m110.165175
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117007, KAKENHI-PROJECT-21248016, KAKENHI-PROJECT-22590262
[Journal Article] Intrinsic oxidativestress causes either two-cell arrest or cell death depending on developmental stage of the embryo from SOD1-deficient mice2010
- Author(s)
  Naoko Kimura, Satoshi Tsunoda, Yoshihito Iuchi, Hiroyuki Abe, Kiyoshi Totsukawa, and Junichi Fujii
- Journal Title
  
  Mol. Hum. Reprod
  
  Volume: 16 Pages: 441-451
- DOI
  10.1093/molehr/gaq007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590262
[Journal Article] B to plasma cell terminal differentiation entails oxidative stress and profound reshaping of the antioxidant responses2010
- Author(s)
  Milena Bertolotti, Sun Hee Yim, Jose M. Garcia-Manteiga, Silvia Masciarelli, Yoo-Jin Kim, Min-Hee Kang, Yoshihito Iuchi, Junichi Fujii, Roberta Vene, Anna Rubartelli, Sue Goo Rhee, Roberto Sitia
- Journal Title
  
  Antioxid Redox Signal
  
  Pages: 1133-1144
- DOI
  10.1089/ars.2009.3079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590262
[Journal Article] Implication of oxidative stress as a cause of autoimmune hemolytic anemia in the NZB mice2010
- Author(s)
  Yoshihito Iuchi, Noriko Kibe, Satoshi Tsunoda, Saori Suzuki, Takeshi Mikami, Futoshi Okada, Koji Uchida, and Junichi Fujii
- Journal Title
  
  Free. Radic. Biol. Med.
  
  Volume: 48 Pages: 935-944
- DOI
  10.1016/j.freeradbiomed.2010.01.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590262
[Journal Article] Molecular mechanisms of inflammation-induced carcinogenesis.2006
- Author(s)
  Okada F, Fujii J
- Journal Title
  
  J Clin Biochem Nutr 39
  
  Pages: 103-113
- Data Source
  KAKENHI-PROJECT-18015006
[Journal Article] Molecular mechanisms of inflammation-induced carcinogenesis.2006
- Author(s)
  Okada F, Fujii J
- Journal Title
  
  J Clin Biochem Nutr 39
  
  Pages: 103-113
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590334
[Journal Article] Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive system2005
- Author(s)
  Fujii, J et al.
- Journal Title
  
  Reprod Biol Endocrinol 3
  
  Pages: 43-52
- Data Source
  KAKENHI-PROJECT-17016007
[Journal Article] Mosby2005
- Author(s)
 Junichi Fujii
- Journal Title
 
 Medical Biochemistry 2^<nd> ed
 
 Pages: 12-12
- Description
 「研究成果報告書概要(欧文)」より
- Data Source
 KAKENHI-PROJECT-16590238
[Journal Article] Prevention of tumor progression as the ultimate goal of cancel therapy.2005
- Author(s)
  Okada F, Fujii J
- Journal Title
  
  Cancer Therapy 3
  
  Pages: 219-226
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590334
[Journal Article] Prevention of tumor progression as the ultimate goal of cancer therapy.2005
- Author(s)
  Okada F, Fujii J
- Journal Title
  
  Cancer Therapy 3
  
  Pages: 219-226
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590334
[Journal Article] Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive system2005
- Author(s)
  Fujii, J et al.
- Journal Title
  
  Reprod Biol Endocrinol 3
  
  Pages: 43-52
- Data Source
  KAKENHI-PROJECT-17590334
[Journal Article] Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive system.2005
- Author(s)
  Fujii J et al.
- Journal Title
  
  Reprod Biol Endocrinol 3
  
  Pages: 43-52
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590334
[Journal Article] Augmented expression of peroxiredoxinVI in rat lung and kidney after birth implies an antioxidative role.2001
- Author(s)
  Fujii, T. et al.
- Journal Title
  
  Eur. J. Biochem. 268
  
  Pages: 218-224
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-10044286
[Journal Article] Augmented expression of peroxiredoxin VI in rat lung and kidney after birth implies an antioxidative role.2001
- Author(s)
  Fujii, T. et al.
- Journal Title
  
  Eur.J.Biochem. 268
  
  Pages: 218-224
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-10044286
[Journal Article] Redox capacity of cells affects inactivation of glutathione reductase by nitrosative stress.2000
- Author(s)
  Fujii, T. et al.
- Journal Title
  
  Archives of Biochemistry and Biophysics 378
  
  Pages: 123-130
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-10044286
[Journal Article] A defect in the mitochondrial import of mutant Min-superoxide dismutase produced in Sf21 cells.1998
- Author(s)
  Fujii, J. et al.
- Journal Title
  
  J.Biochem. 124
  
  Pages: 340-346
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-10044286
[Journal Article] A defect in the mitochondrial import of mutant Mn-superoxide dismutase produced in Sf21 cells.1998
- Author(s)
  Fujii, J. et al.
- Journal Title
  
  J.Biochem. 124
  
  Pages: 340-346
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-10044286
[Presentation] マクロファージの酸化ストレス防御とNO産生におけるシスチン・グルタミン酸トランスポーターの役割2017
- Author(s)
  小林翔、浜島真司、本間拓二郎、藤井順逸、佐藤英世
- Organizer
  第17回日本NO学会
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] シスチントランスポーター・xCT欠損マウスは雄性生殖能が低下する2017
- Author(s)
  本間拓二郎、浜島真司、小林翔、倉橋敏裕、渡辺連、木村直子、佐藤英世、藤井順逸
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] Macrophages from xCT-deficient mice survive under low cysteine/glutathione redox conditions with high oxidative stress.2017
- Author(s)
  Sho Kobayashi , Shinji Hamashima, Takujiro Homma, Junichi Fujii, Hideyo Sato
- Organizer
  OCC World Congress 2017 and Annual SFRR-E Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06648
[Presentation] Macrophages from xCT-deficient mice survive under low cysteine/glutathione redox conditions with high oxidative stress2017
- Author(s)
  Kobayashi Sho , Hamashima Shinji , Takujiro Homma,Fujii Junichi, Sato Hideyo
- Organizer
  OCC World Congress 2017 and Annual SFRR-E Conference; METABOLIC STRESS AND REDOX REGULATION
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] 絶食によるアミノ酸代謝の亢進はオフタルミン酸合成を促進する2017
- Author(s)
  小林翔、李在勇、高尾敏文、藤井順逸
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-16H06648
[Presentation] Production of ophthalmic acid by the glutathione-synthesizing pathway in mouse hepatocytes under cysteine insufficiency2017
- Author(s)
  Lee Jaeyong, Kobayashi Sho, Homma Takujiro, Kang Eun Sil, Sato Hideyo, Seo Han Geuk, Takao Toshifumi, Fujii Junichi
- Organizer
  The 8th Joint Meeting of Society for Free Radical Research Australasia and Japan with International Symposium on Coenzyme Q10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] マクロファージの酸化ストレス防御とNO産生におけるシスチン・グルタミン酸トランスポーターの役割2017
- Author(s)
  小林翔、浜島真司、本間拓二郎、藤井順逸、佐藤英世
- Organizer
  第17回日本NO学会
- Data Source
  KAKENHI-PROJECT-16H06648
[Presentation] xCT欠損によりグルタチオン・レドックスバランスに障害のあるマクロファージの細胞培養系における性質2017
- Author(s)
  小林翔、浜島真司、本間拓二郎、佐藤英世、藤井順逸
- Organizer
  日本生化学会東北支部第83回例会
- Data Source
  KAKENHI-PROJECT-16H06648
[Presentation] 絶食によるアミノ酸代謝の亢進はオフタルミン酸合成を促進する2017
- Author(s)
  小林翔、李在勇、高尾敏文、藤井順逸
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] CoQ10 and ascorbic acid ameliorate reproductive ability of SOD1-deficient female mice2017
- Author(s)
  Fujii Junichi, Ishii Naoki, Homma Takujiro, Lee Jaeyong, Kobayashi Sho, Mitsuhashi Hikaru, Kimura Naoko, Yamamoto Yorihiro
- Organizer
  The 8th Joint Meeting of Society for Free Radical Research Australasia and Japan with International Symposium on Coenzyme Q10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] CoQ10およびアスコルビン酸はSOD1欠損雌マウスの生殖機能を改善する2017
- Author(s)
  石井直樹、本間拓二郎、李在勇、小林翔、三橋輝、木村直子、山本順寛、藤井順逸
- Organizer
  第70回日本酸化ストレス学会
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] Heterozygous SOD1 deficiency causes male infertility by triggering autoimmune response in mice with the NZW background2017
- Author(s)
  Homma Takujiro, Ishii Naoki, Kobayashi Sho, Junichi Fujii
- Organizer
  The 8th Joint Meeting of Society for Free Radical Research Australasia and Japan with International Symposium on Coenzyme Q10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] シスチントランスポーター・xCTの男性生殖能における役割の検討2017
- Author(s)
  本間拓二郎、浜島真司、小林翔、倉橋敏裕、渡辺連、木村直子、佐藤英世、藤井順逸
- Organizer
  第70回日本酸化ストレス学会
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] SOD1欠損による酸化ストレスはシトクロムP450活性を抑制することで薬剤誘発性肝障害を軽減する2016
- Author(s)
  本間拓二郎、白土貴也、李在勇、倉橋敏裕、藤井順逸
- Organizer
  第69回日本酸化ストレス学会
- Place of Presentation
  仙台国際センター会議棟、仙台
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] 精子形成過程におけるシスチントランスポーター・xCTの生理的役割2016
- Author(s)
  浜島真司、本間拓二郎、小林翔、倉橋敏裕、佐藤英世、藤井順逸
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター/東北大学川内キャンパス、仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] SOD1欠損マウスの絶食による腎障害機構2016
- Author(s)
  Lee Jaeyong、本間拓二郎、倉橋敏裕、姜恩實、藤井順逸
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター/東北大学川内キャンパス、仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] 一過性の脂肪蓄積はSOD1欠損マウスの肝臓を酸化ストレスから保護する2016
- Author(s)
  石井直樹、伊藤純一、明原隆介、李在勇、倉橋敏裕、本間拓二郎、藤井順逸
- Organizer
  第69回日本酸化ストレス学会
- Place of Presentation
  仙台国際センター会議棟、仙台
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] 肝臓へのシステイン供給におけるxCTとTranssulfuration経路の役割2016
- Author(s)
  小林翔、姜恩實、李在勇、本間拓二郎、倉橋敏裕、徐漢克、佐藤英世、藤井順逸
- Organizer
  第69回日本酸化ストレス学会
- Place of Presentation
  仙台国際センター会議棟、仙台
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] 肝臓へのシステイン供給におけるxCTとTranssulfuration経路の役割2016
- Author(s)
  小林翔、姜恩實、李在勇、本間拓二郎、倉橋敏裕、徐漢克、佐藤英世、藤井順逸
- Organizer
  第69回日本酸化ストレス学会学術集会
- Place of Presentation
  仙台国際センター会議棟、仙台市、宮城県
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-16H06648
[Presentation] 薬剤性肝障害はSOD1欠損によりを軽減される2016
- Author(s)
  白土貴也、本間拓二郎、李在勇、倉橋敏裕、藤井順逸
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター/東北大学川内キャンパス、仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] Differential contribution of xCT and the transsulfuration pathway as cysteine-supply systems in hepatocytes2016
- Author(s)
  Eun Sil Kang, Jaeyong Lee, Takujiro Homma, Sho Kobayashi, Toshihiro Kurahashi, Han Geuk Seo, Hideyo Sato, Junichi Fujii
- Organizer
  The 9th International Conference on the Biology, Chemistry and Thrapeutic Applications of Nitric Oxide
- Place of Presentation
  Sendai International Center, Sendai
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] 熱ストレス障害に対する小胞体ストレス応答の解析：酸化ストレスはIRE1発現を減少させる2016
- Author(s)
  本間拓二郎、藤井順逸
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター/東北大学川内キャンパス、仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] アルデヒド還元酵素(AKR1a)欠損は四塩化炭素誘発脂肪肝を悪化させる2016
- Author(s)
  明原隆介、本間拓二郎、李在勇、宮田哲、藤井順逸
- Organizer
  第69回日本酸化ストレス学会
- Place of Presentation
  仙台国際センター会議棟、仙台
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] SOD1-knockout mice are resistant to lethal effects of thioacetamide-induced hepatotoxicity2016
- Author(s)
  Takujiro Homma, Takaya Shirato, Jaeyong Lee, Toshihiro Kurahashi, Junichi Fujii
- Organizer
  The 23rd Annual Meeting, a joint meeting with the Society for Free Radical Research International (SfRBM/SFRRI 2016)
- Place of Presentation
  San Francisco, USA
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] 酸化ストレスによるオートファジー障害に起因する脂質代謝異常2015
- Author(s)
  倉橋敏裕、李在勇、白土貴也、浜島真司、本間拓二郎、白澤信行、藤井順逸
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド、神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25870075
[Presentation] 肝臓のシステイン・ホメオスタシスにおけるxCTとトランススルフレーション経路の役割2015
- Author(s)
  姜恩實、李在勇、倉橋敏裕、本間拓二郎、小林翔、佐藤英世、藤井順逸
- Organizer
  第15回日本NO学会
- Place of Presentation
  千里ライフサイエンスセンター、吹田市、大阪府
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] アルデヒド還元酵素AKR1aは四塩化炭素による肝障害からの保護に重要である2015
- Author(s)
  明原隆介、本間拓二郎、宮田哲、藤井順逸
- Organizer
  第88回日本生化学会・第38回日本分子生物学会合同大会
- Place of Presentation
  神戸ポートアイランド、神戸市、兵庫県
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] ストレス応答で起こる脂肪蓄積は肝臓を障害から保護する2015
- Author(s)
  李在勇、本間拓二郎、倉橋敏裕、姜恩實、藤井順逸
- Organizer
  第88回日本生化学会・第38回日本分子生物学会合同大会
- Place of Presentation
  神戸ポートアイランド、神戸市、兵庫県
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] アスコルビン酸によるアセトアミノフェン誘導性酸化ストレスからの肝臓保護作用2015
- Author(s)
  倉橋敏裕、鍋島篤典、李在勇、本間拓二郎、山田壮亮、中山敏幸、宮田哲、藤井順逸
- Organizer
  第68回日本酸化ストレス学会学術集会
- Place of Presentation
  かごしま県民交流センター、鹿児島市
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-25870075
[Presentation] Intrinsic oxidative stress induces accumulation of ubiquitinated and carbonylated proteins in mouse erythrocytes.2015
- Author(s)
  Takujiro Homma, Junichi Fujii.
- Organizer
  7th Joint Meeting of the Societies for Free Radical Research Australasia and Japan
- Place of Presentation
  Christchurch, New Zealand
- Year and Date
  2015-12-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] 薬剤性急性肝障害に対するアスコルビン酸の肝臓保護作用2015
- Author(s)
  倉橋敏裕、鍋島篤典、齋藤由佳、李在勇、本間拓二郎、山田壮亮、中山敏幸、宮田哲、藤井順逸
- Organizer
  第81回日本生化学会東北支部会
- Place of Presentation
  東北大学、仙台市
- Year and Date
  2015-05-19
- Data Source
  KAKENHI-PROJECT-25870075
[Presentation] On the cysteine supply for glutathione synthesis in the liver under oxidative insult.2015
- Author(s)
  Junichi Fujii, Toshihiro Kurahashi, Takujiro Homma, Jaeyong Lee, Eun Sil Kang, Shinji Hamashima, Atsunori Nabeshima, Sohsuke Yamada, Toshiyuki Nakayama, and Hideyo Sato.
- Organizer
  7th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
- Place of Presentation
  Chiang Mai, Thailand
- Year and Date
  2015-11-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] アスコルビン酸によるアセトアミノフェン誘導性酸化ストレスからの肝臓保護作用2015
- Author(s)
  倉橋敏裕、鍋島篤典、李在勇、本間拓二郎、山田壮亮、中山敏幸、宮田哲、藤井順逸
- Organizer
  第68回日本酸化ストレス学会
- Place of Presentation
  かごしま県民交流センター、鹿児島市、鹿児島県
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] 酸化ストレスによる赤血球でのユビキチン・プロテアソーム系の破綻2015
- Author(s)
  本間拓二郎、倉橋敏裕、藤井順逸
- Organizer
  第68回日本酸化ストレス学会
- Place of Presentation
  かごしま県民交流センター、鹿児島市、鹿児島県
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] 酸化ストレスによるオートファジー障害に起因する脂質代謝障害2015
- Author(s)
  倉橋敏裕、李在勇、白土貴也、浜島真司、本間拓二郎、白澤信行、藤井順逸
- Organizer
  第88回日本生化学会・第38回日本分子生物学会合同大会
- Place of Presentation
  神戸ポートアイランド、神戸市、兵庫県
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08294
[Presentation] 臓器の線維化における細胞外基質タンパク質の酸化的折畳み機構に関する研究2014
- Author(s)
  倉橋敏裕、西田隼人、齋藤由香、李在勇、鍋島篤典、山田壮亮、冨田善彦、宮田哲、高尾敏文、藤井順逸
- Organizer
  生化学会東北支部会
- Place of Presentation
  アキタパークホテル（秋田）
- Year and Date
  2014-05-10
- Data Source
  KAKENHI-PROJECT-25870075
[Presentation] The potential roles of PRDX4 as a thiol oxidase in endoplasmic reticulum.2014
- Author(s)
  Toshihiro Kurahashi, Atsunori Nabeshima, Nobuyuki Shirasawa, Sohsuke Yamada, Junitsu Ito, Toshifumi Takao, and Junichi Fujii.
- Organizer
  17th Biennial Meeting of Society for Free Radical Research International
- Place of Presentation
  Kyoto International Conference Center, Kyoto, JAPAN
- Data Source
  KAKENHI-PROJECT-25870075
[Presentation] 体外成熟させたSOD1遺伝子欠損マウス卵でみられる異数性増加の解析2013
- Author(s)
  名古満, 藤井順逸, 木村直子
- Organizer
  第54回日本卵子学会大会
- Place of Presentation
  学術総合センター（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-24580405
[Presentation] SOD1欠損による酸化的ストレスはPrdx4欠損マウスに肝障害を惹起する2013
- Author(s)
  倉橋敏裕、李在勇、鍋島篤典、山田壮亮、白澤信行、伊藤純一、藤井順逸
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド、神戸
- Data Source
  KAKENHI-PROJECT-25870075
[Presentation] マウス初期胚発生におけるビタミンCの役割-活性持続型ビタミンCの効果-2013
- Author(s)
  星野由貴, 鈴木あやめ, 吉田康一, 藤井順逸, 木村直子
- Organizer
  日本畜産学会第117回大会
- Place of Presentation
  新潟大学(新潟市)
- Data Source
  KAKENHI-PROJECT-24580405
[Presentation] 酸化ストレスによる染色体異数性誘発卵における紡錘体形成チェックポイントタンパク質2013
- Author(s)
  名古満, 藤井順逸, 木村直子
- Organizer
  第106回日本繁殖生物学会大会
- Place of Presentation
  東京農工大学農学部府中キャンパス(府中市)
- Data Source
  KAKENHI-PROJECT-24580405
[Presentation] 培養系卵の初期発生におけるビタミンCの役割～アルデヒド還元酵素遺伝子欠損卵を用いた検証～2013
- Author(s)
  星野由貴, 梅田彩, 高橋素子, 宮田哲, 吉田康一, 藤井順逸, 木村直子
- Organizer
  第31回日本受精着床学会総会・学術講演会
- Place of Presentation
  別府国際コンベンションセンター(別府市)
- Data Source
  KAKENHI-PROJECT-24580405
[Presentation] Pleiotropic roles of Peroxiredoxin 4 in Antioxidation, Signal Regulation and Oxidative Protein Folding.2013
- Author(s)
  Toshihiro Kurahashi, Atsunori Nabeshima, Nobuyuki Shirasawa, Sohsuke Yamada, Junitsu Ito, Toshifumi Takao, and Junichi Fujii.
- Organizer
  6th Joint Meeting of the SFRR Australasia and Japan
- Place of Presentation
  Mercure Sydney Hotel, Sydney, Autralia
- Invited
- Data Source
  KAKENHI-PROJECT-25870075
[Presentation] 老齢SOD1欠損マウスにおける排卵数減少の原因解明2013
- Author(s)
  窪田有里子, 藤井順逸, 木村直子
- Organizer
  日本畜産学会第117回大会
- Place of Presentation
  新潟大学(新潟市)
- Data Source
  KAKENHI-PROJECT-24580405
[Presentation] 老齢シスチン・グルタミン酸トランスポーター遺伝子欠損マウスにおける卵巣機能の解析2013
- Author(s)
  渡辺連, 角田智志, 藤井順逸, 佐藤英世, 木村直子
- Organizer
  日本畜産学会第117回大会
- Place of Presentation
  新潟大学(新潟市)
- Data Source
  KAKENHI-PROJECT-24580405
[Presentation] Oxidative stress as a cause for autoimmune hemolytic anemia; supporting evidences from genetically modified mice2012
- Author(s)
  Junichi Fujii
- Organizer
  16th Biennial Meeting of the Society for Free Radical Research International
- Place of Presentation
  ロンドン大学キングスカレッジ（ロンドン・英国）
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] Roles of Peroxiredoxin 4 in ROS Signaling, Oxidative Protein Folding in ER, and Spermatogenesis2012
- Author(s)
  Junichi Fujii (invited speaker)
- Organizer
  UK-Japan Research Symposium; Molecular Mechanisms of Stress Response in Disease
- Place of Presentation
  Tsukuba University, Ibaraki
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] SOD1欠損マウスにおける加齢による排卵卵子数および卵胞数の変化2012
- Author(s)
  窪田有里子, 猪野友香里, 藤井順逸, 木村直子
- Organizer
  第105回日本繁殖生物学会大会
- Place of Presentation
  筑波大学大学会館 (つくば市)
- Data Source
  KAKENHI-PROJECT-24580405
[Presentation] マウス卵初期発生過程におけるアスコルビン酸(VC)含量とVC合成系・取込み系遺伝子の発現2012
- Author(s)
  星野　由貴, 樋口　謙太, 梅田　彩, 高橋　素子, 宮田　哲, 吉田　康一, 藤井　順逸, 木村　直子
- Organizer
  第105回日本繁殖生物学会大会
- Place of Presentation
  筑波大学大学会館 (つくば市)
- Data Source
  KAKENHI-PROJECT-24580405
[Presentation] マウス卵成熟過程でのSOD1欠損による受精障害の解析2012
- Author(s)
  名古満, 佐藤康子, 角田智志, 藤井順逸, 木村直子
- Organizer
  第30回日本受精着床学会総会・学術講演会
- Place of Presentation
  大阪国際会議場(大阪市)
- Data Source
  KAKENHI-PROJECT-24580405
[Presentation] Roles of Peroxiredoxin 4 in ROS Signaling, Oxidative Protein Folding in ER, and Spermatogenesis2012
- Author(s)
  Junichi Fujii
- Organizer
  UK-Japan Research Symposium; Molecular Mechanisms of Stress Response in Disease
- Place of Presentation
  筑波大学（茨城県）
- Invited
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] 赤血球を酸化ストレスによるレドックスバランスの破綻から護る抗酸化機構2011
- Author(s)
  藤井順逸(シンポジスト)
- Organizer
  第64回日本酸化ストレス学会
- Place of Presentation
  ルスツ、北海道
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] SOD1欠損が雄性生殖能に与える影響2011
- Author(s)
  角田智志、藤井順逸
- Organizer
  第64回日本酸化ストレス学会
- Place of Presentation
  ルスツリゾートホテル・コンベンション(ルスツ,北海道)
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] Peroxiredoxin 4 is a multifunctional redox protein working in endoplasmic reticulum and cytoplasm2011
- Author(s)
  Junichi Fujii (poster), Yoshihito Iuchi, Xuhong Zhang, Satoshi Tsunoda, and Yoshitaka Ikeda
- Organizer
  International Symposium on Free Radical Research: Contribution to Medicine (FRCM2011)
- Place of Presentation
  Iburikawa, Kyoto
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] 活性酸素のもつ二面性:生体傷害と細胞増殖・老化の制御2011
- Author(s)
  藤井順逸
- Organizer
  第12回Vitamemebrane研究会
- Place of Presentation
  経団連会館(東京)(招待講演)
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] Influences of the SOD1 deficiency on the gamete quality in in-vitro fertilization2011
- Author(s)
  Satoshi Tsunoda, Naoko Kimura, Hiroyuki Abe, Akihiro Watanabe, Junichi Fujii
- Organizer
  5th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia), 8th Conference of Asian Society for Mitochondrial Research and Medicine (ASMRM)
- Place of Presentation
  Kagoshima Citizens' Culture Hall (Kagoshima)
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] 赤血球を酸化ストレスによるレドックスバランスの破綻から護る抗酸化機構2011
- Author(s)
  藤井順逸
- Organizer
  第64回日本酸化ストレス学会
- Place of Presentation
  ルスツリゾートホテル・コンベンション(ルスツ,北海道)(招待講演)
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] 過酸化PeoxiredoxinIIの検出による赤血球レドックスバランスと機能の解明2011
- Author(s)
  伊藤純一、倉橋敏裕、金野祐、大槻倫之、角田智志、張旭紅、藤井順逸
- Organizer
  第84回日本生化学会
- Place of Presentation
  国立京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] Roles of peroxiredoxin 4 in protein sulfhyryl oxidation2011
- Author(s)
  Toshihiro Kurahashi, Chihiro Awada. Tasuku Konno, Noriyuki Otsuki, Satoshi Tsunoda, Xuhong Zhang, Junitsu Ito, Yoshihito Iuchi, Toshifumi Takao, Junichi Fujii
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] 炎症発癌を標的とした予防化合物の定量的検出系の開発2011
- Author(s)
  末永裕佳、坂木隆太、小沼邦重、村上明、田中宏樹、浜田淳一、小林正伸、藤井順逸、岡田太
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] 肝細胞癌におけるmiR-224の機能解析2011
- Author(s)
  張旭紅、邵力、渡辺久剛、縢亮、齋藤貴史、石井里佳、横澤潤二、木村理、藤井順逸、深尾彰
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] NZマウスの自己免疫疾患発症に対する赤血球酸化名kストレスの関与2011
- Author(s)
  金野祐、大槻倫之、鈴木紗織、岐部紀子、角田智志、井内良仁、藤井順逸
- Organizer
  第84回日本生化学会
- Place of Presentation
  国立京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] Aldehyde reductase deficiency prolongs pentobarbital induced hypsosis in mice2011
- Author(s)
  Junitsu Ito, Motoko Takahashi, Noriyuki Otsuki, Tasuku Konno, Hayato Nishida, Satoshi Tsunoda, Toshihiro Kurahashi, Xuhong Zhang, Satoshi Miyata, Junichi Fujii
- Organizer
  4th Symposium on Nutrition, Oxygen Biology and Medicine
- Place of Presentation
  Hotel de Seine (Paris, France)
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] Roles of peroxiredoxin 4 in protein sulfhyryl oxidation2011
- Author(s)
  Toshihiro Kurahashi, Chihiro Awada, Tasuku Konno, Noriyuki Otsuki, Satoshi Tsunoda, Xuhong Zhang, Junitsu Ito, Yoshihito Iuchi, Toshifumi Takao, Junichi Fujii
- Organizer
  5th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia), 8th Conference of Asian Society for Mitochondrial Research and Medicine (ASMRM)
- Place of Presentation
  Kagoshima Citizens' Culture Hall (Kagoshima)
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] 酸化還元酵素アルデヒドレダクターゼノックアウトマウスで発症するアスコルビン酸欠乏症とその影響2011
- Author(s)
  高橋素子、宮田哲、藤井順逸、井内陽子、上山茂充、曽我朋義、藤縄玲子、荒木素子、谷口直之、黒木由夫
- Organizer
  第64回日本酸化ストレス学会
- Place of Presentation
  ルスツリゾートホテル・コンベンション(ルスツ,北海道)
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] 内因性酸ストレス蓄積によマウス2細胞期発生停止へのCDKインヒビターの関与の可能性2011
- Author(s)
  角田智志、木村直子、藤井順逸
- Organizer
  第52回日本哺乳動物卵子学会
- Place of Presentation
  国際医療福祉大学(大田原)
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] SOD1欠損マウス胎仔線維芽細胞を用いた酸化ストレス誘導性細胞周期停止機構の解析2011
- Author(s)
  角田智志、岐部紀子、藤井順逸
- Organizer
  第84回日本生化学会
- Place of Presentation
  国立京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] Peroxiredoxin 4 is a multifunctional redox protein working in endoplasmic reticulum and cytoplasm2011
- Author(s)
  Fujii, Junichi
- Organizer
  International Symposium on Free Radical Research
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] Implication of oxidative stress as a cause of autoimmune hemolytic anemia2011
- Author(s)
  Yoshihito Iuchi, Futoshi Okada, Junichi Fujii
- Organizer
  Montreal, Modern Medical Forum 2011
- Place of Presentation
  EPS Global Medical Development Inc.(Montreal, Canada)
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] ベルオキシレドキシンによる抗酸化と活性酸素シグナルの制御2010
- Author(s)
  藤井順逸
- Organizer
  第27回臨床フリーラジカル会議
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] Prx4の抗酸化活性による活性酸素シグナルの制御2010
- Author(s)
  藤井順逸(ワークショップ)
- Organizer
  第33回日本分子生物学会第83回日本生化学合同年会
- Place of Presentation
  神戸国際会議場、兵庫
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] SOD1欠損マウス胎児線維芽Prx4の抗酸化活性による活性酸素シグナルの制御2010
- Author(s)
  藤井順逸
- Organizer
  第33回日本分子生物学会第83回日本生化学合同年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590262
[Presentation] MI期動原体へのBubR1の局在性低下が卵染色体の異数性を増加させる～成熟培養系SOD1遺伝子欠損マウス卵を用いた研究～
- Author(s)
  名古満, 藤井順逸, 木村直子
- Organizer
  第32回日本受精着床学会総会・学術講演会
- Place of Presentation
  ハイアットリージェンシー東京（東京都新宿区）
- Year and Date
  2014-07-31 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-24580405
[Presentation] The role of vitamin C in in vitro mouse early embryonic developmsent －the effects of supplementationof ascorbic acid 2-phosphate-
- Author(s)
  Yuki Hoshino, Ren Watanabe, Koichi Yoshida,Junichi Fujii, Naoko Kimura
- Organizer
  World Congress of Reproductive Biology 2014
- Place of Presentation
  Edinburgh (Scotland)
- Year and Date
  2014-09-02 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-24580405
[Presentation] 臓器線維化における細胞外基質蛋白質の酸化的折畳みに働く小胞体チオールオキシダーゼとアスコルビン酸に関する研究
- Author(s)
  倉橋敏裕、西田隼人、齋藤由香、李在勇、鍋島篤典、山田壮亮、冨田善彦、宮田哲、高尾敏文、藤井順逸
- Organizer
  日本酸化ストレス学会
- Place of Presentation
  同志社大学（京都）
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25870075
[Presentation] Evaluation of oocyte quality and ovarian function in aged female cystine-glutamate transporter gene-deficient mice
- Author(s)
  Ren Watanabe, Junichi Fujii, Hideyo Sato, Naoko Kimura
- Organizer
  World Congress of Reproductive Biology 2014
- Place of Presentation
  Edinburgh (Scotland)
- Year and Date
  2014-09-02 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-24580405
[Presentation] アセトアミノフェン急性肝障害におけるアスコルビン酸とチオール化合物の肝臓保護作用
- Author(s)
  倉橋敏裕、鍋島篤典、齋藤由香、李在勇、本間拓二郎、山田壮亮、中山敏幸、佐藤英世、宮田哲、藤井順逸
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25870075
[Presentation] Intrinsic oxidative stress increases meiotic chromosome misalignment and aneuploidy in in vitro matured oocytes from SOD1-deficient mice
- Author(s)
  Naoko Kimura, Mitsuru Nago, Kazuharu Odajima, and Junichi Fujii
- Organizer
  World Congress of Reproductive Biology 2014
- Place of Presentation
  Edinburgh (Scotland)
- Year and Date
  2014-09-02 – 2014-09-04
- Invited
- Data Source
  KAKENHI-PROJECT-24580405

1. TANIGUCHI Naoyuki (90002188)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. SUZUKI Keiichiro (70221322)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. HIGASHIYAMA Shigeki (60202272)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. OKADA Futoshi (00250423)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
5. CHUNG Mun Ok (60252657)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. Kurahashi Toshihiro (00596570)

# of Collaborated Projects: 2 results

# of Collaborated Products: 46 results
7. HOMMA Takujiro (70743566)

# of Collaborated Projects: 2 results

# of Collaborated Products: 52 results
8. KOBAYASHI Sho (10779490)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
9. YOSHIHITO Iuchi (60272069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
10. KIMURA Naoko (70361277)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
11. SUGIYAMA Toshihiro (00127242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. IHARA Yoshito (70263241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KONDO Takahito (00158908)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TAKAHASHI Motoko (00303941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. SATO Hideyo (60235380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
16. TAKAO Toshifumi (10197048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. 葛巻丈二朗 (70211208)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 泰地真弘人 (10242025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. CHOUVAEV Vladimir V

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YAMAMOTO Hirotaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. DENNIS James W

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. DEUTSCH Harold F

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. ANDERSON Mary E

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. SIEST Gerard

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SCHACHTER Harry

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. ITOH Satoru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. LEE Jaeyong

# of Collaborated Projects: 1 results

# of Collaborated Products: 30 results
28. SHIBATA Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. SATOH Kiyotoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. SUGIMOTO Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 真崎雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 山田壮亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 内田浩二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 内海俊彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 山川光徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 曽我朋義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 宮田浩文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 宮戸健二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUJII Junichi 藤井 順逸

FIJII Junichi 藤井 順逸

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一酸化窒素(NO)合成酵素由来と外因性NOによるスーパーオキシドの毒性軽減の証明Principal InvestigatorOngoing

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Roles of transsulfuration-mediated cysteine uptake and hydrogen sulfide in liverPrincipal Investigator

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Redox regulation of endoplasmic reticulum stress and signals by reactive oxygen speciesPrincipal Investigator

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Analyses of Roles of SOD1 in Protection against Photoaging and Carcinogenesis Using SOD1-deficient MicePrincipal Investigator

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Investigation on a role of Prx4 in spermatogenesis by gene knockout approachPrincipal Investigator

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Development of a method for early diagnosis of diabetic of complications by detecting glycation reaction intermediates.Principal Investigator

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FUJII Junichi 藤井順逸

FIJII Junichi 藤井順逸