• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

FUJII Junichi  藤井 順逸

ORCIDConnect your ORCID iD *help
… Alternative Names

FIJII Junichi  藤井 順逸

Less
Researcher Number 00222258
Other IDs
Affiliation (Current) 2020: 山形大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2016 – 2019: 山形大学, 大学院医学系研究科, 教授
2016: 山形大学, 大学院医学研究科, 教授
2015: 山形大学, 医学(系)研究科(研究院), 教授
2014: 山形大学, 大学院医学研究科, 教授
2012: 山形大学, 医学(系)研究科(研究院), 教授 … More
2010 – 2012: 山形大学, 大学院・医学系研究科, 教授
2007: 山形大学, 大学院・医学系研究科, 教授
2006: Yamagata University, Department of Biomolecular Function, Graduate School of Medical Science, Professor, 大学院医学系研究科, 教授
2004 – 2005: 山形大学, 大学院・医学系研究科, 教授
1999 – 2002: 山形大学, 医学部, 教授
1996 – 1998: Medical School, Osaka University, 医学部, 助教授
1992 – 1995: Department of Biochemistry, Osaka University Medical School, 医学部, 講師
1991: 大阪大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Pathological medical chemistry / General medical chemistry / Pathological medical chemistry / General medical chemistry / Structural biochemistry / Basic Section 49010:Pathological biochemistry-related
Except Principal Investigator
Biological Sciences / Pathological medical chemistry / Pathological medical chemistry / Applied animal science … More / General medical chemistry / Functional biochemistry / Experimental pathology / General medical chemistry Less
Keywords
Principal Investigator
一酸化窒素 / アポトーシス / グルタチオン / ペルオキシ亜硝酸イオン / glutathione / SOD1 / Antioxidative Enzyme / Cu,Zn-superoxide Dismutase / Amyotrophic Lateral Sclerosis / Reactive oxygen … More / Motor neuron / Baculovirus / 一酸化窒素合成酵素 / バキュロウイルス / 血管平滑筋 / グルタチオンペルオキシダーゼ / セレノシステイン / DNAトランスフェクト / 小胞体ストレス / レドックス調節 / 活性酸素シグナル / シャペロン / 糖尿病性合併症 / グリケーション / クリスタリン / グルコース / フルクトース / ポリオール代謝経路 / 白内症 / Diabetic complicatrions / Glycation / Crystallin / Glucose / Fructose / Polyol pathway / Cataract / 増殖因子 / シグナル伝達 / EGF受容体 / EGF-受容体 / Apoptosis / Growth factor / Signal transduction / EGF receptor / 遺伝子改変 / レドックス酵素 / 精子形成 / ペルオキシレドキシン / 酸化ストレス / gene knockout / redox enzyme / spermatogenesis / peroxiredoxin / oxidative stress / ケラチノサイト / 一重項酸素 / チトクローム-c / keratinocyte / singlet oxygen / apoptosis / cytochrome-c / システイン / 肝障害 / トランススルフィレーション経路 / スーパーオキシド / ペルオキシ亜硝酸 … More
Except Principal Investigator
活性酸素 / グルタチオン / 一酸化窒素 / ペルオキシレドキシン / TNF / 血管内皮細胞 / 酸化ストレス / グリケーション / Mn-SOD / Glycation / アポトーシス / Reactive oxygen species / SOD / プロテオミクス / MnーSOD / 上皮性卵巣癌 / ILー1 / カルボ-ルエステル / プロテインキナ-ゼーC / 腫瘍マーカー / Mn-スーパーオキサイドディスムターゼ / 抗酸化酵素 / 過酸化物 / 卵巣癌 / IL-1 / HB-EGF / オートクリン活性 / ジャクスタクリン活性 / EGF受容体 / CD9 / 紫外線 / p21 / 炎症発癌 / 好中球 / 合成ペプチド / 炎症細胞 / β2インテグリン / LFA1 / ロヴァスタチン / 分子シミュレーション / 減数分裂 / 卵母細胞 / 異数性 / 体外成熟,IVM / 紡錘体形成チェックポイント / 発生障害 / 老化 / IVM / 卵成熟 / 培養系 / LECラット / DNA低メチル化 / ウィルソン病モデル動物 / 肝薬物代謝酵素 / 肝炎 / 肝癌 / メチオニン代謝異常 / メチル基代謝 / Sーアデノシルメチオニン合成酵素 / 肝細胞分画 / 肝炎モデル / 肝癌自然発症 / ウイルソン病 / DNA hypomethylation / spontaneous hepatitis / hepatoma / LEC rat / drug metabolism / choline-deficient diet / Cytochrome P450 / Wilson's disease / フェントン反応 / ヒドロキシラジカル / バキュロウィルス / 筋萎縮性側索硬化症 / Cu,Zn-SOD / バキュロウイルス / DNA fragmentation / Diabetes / Hydroxy radical / Mutation / FALS / DNA damage / Hydroxyl radical / Cu, Zn-SOD / Amyotrophic lateral sclerosis / TGF-beta / 糖尿病 / 血管平滑筋 / 糖化反応 / 部位特異的変異 / アポリポプロテインE / ヘパリン結合性EGF様増殖因子 / γ-グルタミルトランスペプチダーゼ / r-グルタミルトランスペプチダーゼ / 糖鎖遺伝子 / γ-glutamyl transpeptidase / 糖タンパク質 / 糖転移酵素 / アポプロテインE / diabetes / vascular smooth muscle / glycation / site-directed mutagenesis / apolipoprotein E / heparin binding EGF-like growth factor / gamma-glutamyl transpeptidase / 活性酸素種 / 抗酸化剤 / 糖尿病性合併症 / 増殖因子 / 3-デオキシグルコソン / シグナル伝達 / 形質転換増殖因子 / ヘパリン結合性上皮増殖因子 / 2-オキソアルデヒド化合物 / スーパーオキシドディスムターゼ / グルタチオンペルオキシダーゼ / Antioxidants / Apoptosis / Diabetic complications / Growth factor / 3-Deoxyglucosone / Signal transduction / 抗酸化物質 / NO (peroxynitrite) / endothelial cells / apoptosis / glutathione / reactive oxygen species / セルロプラスミン / チオレドキシン / ベルオキシレドキシン / NO合成酵素 / glutathine / nitric oxide / redox balance / growth factor / glutathione peroxidase / 低酸素再酸素化 / フリーラジカル / 発癌 / DNAマイクロアレイ / 悪性化 / Hypoxia reperfusion / Free radical / Carcinogenesis / DNA microarray / Proteomics / Prx4 / 小胞体 / 蛋白質の酸化的折畳み / システイン / xCT / ferroptosis / マクロファージ / オフタルミン酸 / xCT / Ferroptosis / 癌 / シスチン輸送体 / セレン Less
  • Research Projects

    (26 results)
  • Research Products

    (196 results)
  • Co-Researchers

    (50 People)
  •  一酸化窒素(NO)合成酵素由来と外因性NOによるスーパーオキシドの毒性軽減の証明Principal InvestigatorOngoing

    • Principal Investigator
      藤井 順逸
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Yamagata University
  •  Elucidation of induction of ferroptosis and inhibition of tumor growth caused by suppressing cystine transporter xCT

    • Principal Investigator
      Kobayashi Sho
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Yamagata University
  •  Roles of transsulfuration-mediated cysteine uptake and hydrogen sulfide in liverPrincipal Investigator

    • Principal Investigator
      Fujii Junichi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Yamagata University
  •  Studies on the physiological role of Prx4 in oxidative protein folding

    • Principal Investigator
      Kurahashi Toshihiro
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
      General medical chemistry
    • Research Institution
      Kyoto Prefectural University of Medicine
      Yamagata University
  •  Investigation into the cause of oocyte aneuploidy using antioxidant capasity deficient mice and application to advanced IVM methods

    • Principal Investigator
      KIMURA Naoko
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied animal science
    • Research Institution
      Yamagata University
  •  Redox regulation of endoplasmic reticulum stress and signals by reactive oxygen speciesPrincipal Investigator

    • Principal Investigator
      FUJII Junichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Yamagata University
  •  炎症発癌を標的としたロヴァスタチンの結合構造情報に基づく化合物探索

    • Principal Investigator
      岡田 太
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yamagata University
  •  炎症発がんを標的としたペプチド治療法の開発

    • Principal Investigator
      OKADA Futoshi
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yamagata University
  •  Hypoxia-to-reoxygenation condition as one of the internal carcinogenic factors of common cancers

    • Principal Investigator
      OKADA Futoshi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Yamagata University
  •  Analyses of Roles of SOD1 in Protection against Photoaging and Carcinogenesis Using SOD1-deficient MicePrincipal Investigator

    • Principal Investigator
      FUJII Junichi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Yamagata University
  •  Investigation on a role of Prx4 in spermatogenesis by gene knockout approachPrincipal Investigator

    • Principal Investigator
      FUJII Junichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Yamagata University School of Medicine
  •  皮膚癌を誘発する紫外線からの新規抗酸化酵素ペルオキシレドキシンによる防御機構

    • Principal Investigator
      葛巻 丈二朗
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Yamagata University
  •  Redox regulation by glutathione and the roles of reactive oxygen and nitrogen species

    • Principal Investigator
      TANIGUCHI Naoyuki
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  Development of a method for early diagnosis of diabetic of complications by detecting glycation reaction intermediates.Principal Investigator

    • Principal Investigator
      FUJII Junichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  Remodeling of regulation of cell growth by glycogene and its application.Principal Investigator

    • Principal Investigator
      FUJII Junichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Osaka University
  •  一酸化窒素の細胞毒性とグルタチオンペルオキシダーゼ不活性化機構Principal Investigator

    • Principal Investigator
      藤井 順逸
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University
  •  Regulation of Cellular Activity by Reactive Oxygen

    • Principal Investigator
      TANIGUCHI Naoyuki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Osaka University
  •  Mechanisms of apoptosis of endothelial and vascular smooth muscle cells by reactive oxygen species -Relationship with the initiation of arteriosclerosis-

    • Principal Investigator
      SUZUKI Keiichiro
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  血管系における一酸化窒素(NO)産生とNO合成酵素の活性調節機構に関する研究Principal Investigator

    • Principal Investigator
      藤井 順逸
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  Significance of sugar moiery of recombinant glycoproteins

    • Principal Investigator
      TANIGUCHI Naoyuki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  ジャクスタクリン機構を介した細胞膜結合型細胞増殖因子と癌細胞増殖

    • Principal Investigator
      東山 繁樹
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Cu,Zn-スーパーオキサイドディスムターゼの変異と筋萎縮性側索硬化症Principal Investigator

    • Principal Investigator
      藤井 順逸
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  Site-specific fragmentation of superoxide dismutase and DNA damage

    • Principal Investigator
      TANIGUCHI Naoyuki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University
  •  腫瘍マーカーとしてのMn-スーパーオキサイドディスムターゼの癌化による発現機構Principal Investigator

    • Principal Investigator
      藤井 順逸, 谷口 直之
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  腫瘍マ-カ-としてのMnース-パ-オキサイドディスムタ-ゼの癌化による発現機構

    • Principal Investigator
      TANIGUCHI Naoyuki
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Correlation between the spontaneous hepatitis and hepatoma and the disorder of methyl group metabolism in LEC rats

    • Principal Investigator
      SUGIYAMA Toshihiro
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Akita University
      Osaka University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2006 2005 2001 2000 1998 Other

All Journal Article Presentation Book

  • [Book] Superoxide Dismutase (SOD): Sources, Therapeutic Uses and Health Benefits2016

    • Author(s)
      Takujiro Homma, Junichi Fujii
    • Total Pages
      197
    • Publisher
      Nova Science Publishers, Inc
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Book] Ascorbic Acid: Properties, Synthesis and Applications2016

    • Author(s)
      Junichi Fujii, Takujiro Homma, Sho Kobayashi
    • Total Pages
      285
    • Publisher
      Nova Science Publishers, Inc
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Book] Handbook of System Biology of Free Radicals and Anti-oxidants2013

    • Author(s)
      Junichi Fujii
    • Total Pages
      17
    • Publisher
      Antithetical Roles of Reactive Oxygen Species in Mammalian Reproduction
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Book] Antithetical Roles of Reactive Oxygen Species in Mammalian Reproduction r In Handbook of System Biology of Free Radicals and Anti-oxidants2013

    • Author(s)
      Junichi Fujii, Satoshi Tsunoda, and Naoko Kimura
    • Publisher
      Springer-Verlag(I. Larher ed)(in press)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Book] Antithetical Roles of Reactive Oxygen Species in Mammalian Reproduction r In Handbook of System Biology of Free Radicals and Anti-oxidants. (I. Larher ed)2012

    • Author(s)
      Junichi Fujii, Satoshi Tsunoda, and Naoko Kimura.
    • Total Pages
      17
    • Publisher
      Springer-Verlag, Germany, in press (2012)
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Book] Handbook of System Biology of Free Radicals and Anti-oxidants2012

    • Author(s)
      Junichi Fujii, Satoshi Tsunoda, Naoko Kimura
    • Publisher
      Antithetical Roles of Reactive Oxygen Species in Mammalian Reproduction(印刷中)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Book] Male and Female Infertility:Genetic Causes, Hormonal Treatments and Health Effects2010

    • Author(s)
      Fujii, Junichi
    • Total Pages
      22
    • Publisher
      Nova Science Publishers
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Book] Medical Biochemistry 2^<nd> ed2005

    • Author(s)
      J Fujii
    • Total Pages
      12
    • Publisher
      M.H.Dominiczak and J.W.Baynes
    • Data Source
      KAKENHI-PROJECT-16590238
  • [Book] Medical Biochemistry 2^<nd> ed2005

    • Author(s)
      Junichi Fujii
    • Total Pages
      12
    • Publisher
      Mosby
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590238
  • [Journal Article] Ascorbic acid and CoQ10 ameliorate the reproductive ability of superoxide dismutase 1-deficient female mice2020

    • Author(s)
      Ishii Naoki、Homma Takujiro、Lee Jaeyong、Mitsuhashi Hikaru、Yamada Ken-ichi、Kimura Naoko、Yamamoto Yorihiro、Fujii Junichi
    • Journal Title

      Biol Reprod.

      Volume: 102 Pages: 102-115

    • DOI

      10.1093/biolre/ioz149

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-17H03977, KAKENHI-PROJECT-17K19316, KAKENHI-PROJECT-18K19405
  • [Journal Article] Emerging connections between oxidative stress, defective proteolysis, and metabolic diseases2020

    • Author(s)
      Homma Takujiro, Fujii Junichi
    • Journal Title

      Free Radical Research

      Volume: -

    • DOI

      10.1080/10715762.2020.1734588

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Journal Article] γ-Glutamylcysteine synthetase and γ-glutamyl transferase as differential enzymatic sources of γ-glutamylpeptides in mice.2020

    • Author(s)
      Kobayashi Sho, Ikeda Yoshitaka, Shigeno Yuhei, Konno Hiroyuki, Fujii Junichi
    • Journal Title

      Amino Acid

      Volume: - Pages: 555-566

    • DOI

      10.1007/s00726-020-02835-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-18K15039
  • [Journal Article] Edaravone, a free radical scavenger, protects against ferroptotic cell death in vitro2019

    • Author(s)
      Homma Takujiro、Kobayashi Sho、Sato Hideyo、Fujii Junichi
    • Journal Title

      Experimental Cell Research

      Volume: 384 Pages: 111592-111592

    • DOI

      10.1016/j.yexcr.2019.111592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-18K15039
  • [Journal Article] An SOD1 deficiency aggravates proteasome inhibitor bortezomib-induced testicular damage in mice2019

    • Author(s)
      Homma Takujiro、Fujii Junichi
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - General Subjects

      Volume: 1863 Pages: 1108-1115

    • DOI

      10.1016/j.bbagen.2019.04.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Journal Article] Quantitative analysis of γ-glutamylpeptides by liquid chromatography-mass spectrometry and application for γ-glutamyltransferase assays2019

    • Author(s)
      Kobayashi Sho、Tokairin Yoshinori、Miyakoshi Takeru、Saito Takuya、Nagaoka Keita、Ikeda Yoshitaka、Fujii Junichi、Konno Hiroyuki
    • Journal Title

      Analytical Biochemistry

      Volume: 578 Pages: 13-22

    • DOI

      10.1016/j.ab.2019.04.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-18K15039
  • [Journal Article] Elevated ER stress exacerbates dextran sulfate sodium-induced colitis in PRDX4-knockout mice.2019

    • Author(s)
      Takagi T, Homma T, Fujii J, Shirasawa N, Yoriki H, Hotta Y, Higashimura Y, Mizushima K, Hirai Y, Katada K, Uchiyama K, Naito Y, Itoh Y.
    • Journal Title

      Free Radic Biol Med.

      Volume: 134 Pages: 153-164

    • DOI

      10.1016/j.freeradbiomed.2018.12.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K05475, KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-16K09322, KAKENHI-PROJECT-18K06224
  • [Journal Article] A heterozygous deficiency in protein phosphatase Ppm1b results in an altered ovulation number in mice.2019

    • Author(s)
      Ishii Naoki ,Homma Takujiro, Watanabe Ren, Kimura Naoko, Ohnishi Motoko, Kobayashi Takayasu, Fujii Junichi
    • Journal Title

      Mol Med Report

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Journal Article] Ferroptosis caused by cysteine insufficiency and oxidative insult2019

    • Author(s)
      Fujii Junichi、Homma Takujiro、Kobayashi Sho
    • Journal Title

      Free Radical Research

      Volume: - Pages: 1-12

    • DOI

      10.1080/10715762.2019.1666983

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-18K15039
  • [Journal Article] Induction of ferroptosis by singlet oxygen generated from naphthalene endoperoxide2019

    • Author(s)
      Homma Takujiro、Kobayashi Sho、Fujii Junichi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 518 Pages: 519-525

    • DOI

      10.1016/j.bbrc.2019.08.073

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-18K15039
  • [Journal Article] Ascorbic acid insufficiency impairs spatial memory formation in juvenile AKR1A-knockout mice2019

    • Author(s)
      Kurihara Kazuki、Homma Takujiro、Kobayashi Sho、Shichiri Mototada、Fujiwara Hiroki、Fujii Satoshi、Yamada Ken-ichi、Nakane Masaki、Kawamae Kaneyuki、Fujii Junichi
    • Journal Title

      J. Clin. Biochem. Nutr.

      Volume: 65 Issue: 3 Pages: 209-216

    • DOI

      10.3164/jcbn.19-41

    • NAID

      130007706088

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-17H03977, KAKENHI-PROJECT-18K19405, KAKENHI-PROJECT-18K15039
  • [Journal Article] A heterozygous deficiency in protein phosphatase Ppm1b results in an altered ovulation number in mice2019

    • Author(s)
      Ishii Naoki、Homma Takujiro、Watanabe Ren、Kimura Naoko、Ohnishi Motoko、Kobayashi Takayasu、Fujii Junichi
    • Journal Title

      Molecular Medicine Reports

      Volume: 19 Pages: 5353-5360

    • DOI

      10.3892/mmr.2019.10194

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K01810, KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-19K09016, KAKENHI-PROJECT-17K19316
  • [Journal Article] An SOD1 deficiency aggravates proteasome inhibitor bortezomib-induced testicular damage.2019

    • Author(s)
      Homma Takujiro, Fujii Junichi
    • Journal Title

      Bichim Biophys Acta

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Journal Article] The association of peroxiredoxin 4 with the initiation and progression of hepatocellular carcinoma.2019

    • Author(s)
      Guo X, Noguchi H, Ishii N, Homma T, Hamada T, Hiraki T, Zhang J, Matsuo K, Yokoyama S, Ishibashi H, Fukushige T, Kanekura T, Fujii J, Uramoto H, Tanimoto A,Yamada S.
    • Journal Title

      Antioxid Redox Signal

      Volume: 30 Pages: 1271-1284

    • DOI

      10.1089/ars.2017.7426

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10803, KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-16H05513, KAKENHI-PROJECT-16K08750
  • [Journal Article] Heterozygous SOD1 deficiency in mice with an NZW background causes male infertility and an aberrant immune phenotype2019

    • Author(s)
      Homma Takujiro、Takeda Yuji、Sakahara Satoshi、Ishii Naoki、Kobayashi Sho、Abe Hiroyuki、Asao Hironobu、Fujii Junichi
    • Journal Title

      Free Radical Research

      Volume: 53 Pages: 1060-1072

    • DOI

      10.1080/10715762.2019.1677901

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-18K19898, KAKENHI-PROJECT-19H04481, KAKENHI-PROJECT-18K15039
  • [Journal Article] Mice deficient in aldo-keto reductase 1a (Akr1a) are resistant to thioacetamide-induced liver injury2018

    • Author(s)
      Homma T., Shirato T., Akihara R., Kobayashi S., Lee J., Yamada K., Miyata S., Takahashi M., Fujii J.
    • Journal Title

      Toxicology Letters

      Volume: 294 Pages: 37-43

    • DOI

      10.1016/j.toxlet.2018.05.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07339, KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-18K15039
  • [Journal Article] Potential involvement of ubiquitin-proteasome system dysfunction associated with oxidative stress in the pathogenesis of sickle cell disease2018

    • Author(s)
      Warang Prashant、Homma Takujiro、Pandya Riddhi、Sawant Anuja、Shinde Nikhil、Pandey Debjeet、Fujii Junichi、Madkaikar Manisha、Mukherjee Malay B.
    • Journal Title

      British Journal of Haematology

      Volume: 182 Pages: 559-566

    • DOI

      10.1111/bjh.15437

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Journal Article] Oxidative stress caused by an SOD1 deficiency triggers the accumulation of oxidatively-modified carbonic anhydrase II in erythrocytes.2018

    • Author(s)
      Takujiro Homma, Junichi Fujii
    • Journal Title

      Reactive Oxygen Species

      Volume: 6 Pages: 289-298

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Journal Article] Mutual interaction between oxidative stress and endoplasmic reticulum stress in the pathogenesis of diseases specifically focusing on non-alcoholic fatty liver disease2018

    • Author(s)
      Fujii Junichi、Homma Takujiro、Kobayashi Sho、Seo Han Geuk
    • Journal Title

      World Journal of Biological Chemistry

      Volume: 9 Pages: 1-15

    • DOI

      10.4331/wjbc.v9.i1.1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-18K15039
  • [Journal Article] Double Knockout of Peroxiredoxin 4 (Prdx4) and Superoxide Dismutase 1 (Sod1) in Mice Results in Severe Liver Failure2018

    • Author(s)
      Homma T, Kurahashi T, Lee J, Nabeshima A, Yamada S, Fujii J.
    • Journal Title

      Oxidative Medicine and Cellular Longevity

      Volume: 2018

    • DOI

      10.1155/2018/2812904

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K01365, KAKENHI-PROJECT-18K06948
  • [Journal Article] Unveiling systemic organ disorders associated with impaired lipid catabolism in fasted SOD1-deficient mice2018

    • Author(s)
      Lee Jaeyong、Homma Takujiro、Kobayashi Sho、Ishii Naoki、Fujii Junichi
    • Journal Title

      Archives of Biochemistry and Biophysics

      Volume: 654 Pages: 163-171

    • DOI

      10.1016/j.abb.2018.07.020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-18K15039
  • [Journal Article] Expression of TRPM8 in human reactive lymphoid tissues and mature B?cell neoplasms2018

    • Author(s)
      Hirai A, Aung NY, Ohe R, Nishida A, Kato T, Meng H, Ishizawa K, Fujii J, Yamakawa M
    • Journal Title

      Oncology Letters

      Volume: 16 Pages: 5930-5938

    • DOI

      10.3892/ol.2018.9386

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08736, KAKENHI-PROJECT-18K06948
  • [Journal Article] Cystine/glutamate transporter, system x c - , is involved in nitric oxide production in mouse peritoneal macrophages2018

    • Author(s)
      Kobayashi S、Hamashima S、Homma T、Sato M、Kusumi R、Bannai S、Fujii J、Sato H
    • Journal Title

      Nitric Oxide

      Volume: 78 Pages: 32-40

    • DOI

      10.1016/j.niox.2018.05.005

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K01829, KAKENHI-PROJECT-17K07158, KAKENHI-PROJECT-17K08977, KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-18K15039
  • [Journal Article] Decreased reproductive performance in xCT-knockout male mice2017

    • Author(s)
      Hamashima, S., Homma, T., Kobayashi, S., Ishii, N., Kurahashi, T., Watanabe, R., Kimura, N., Sato, H., and Fujii, J.
    • Journal Title

      Free Radic Res

      Volume: 51 Pages: 851-860

    • DOI

      10.1080/10715762.2017.1388504

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K01829, KAKENHI-PROJECT-17K01365, KAKENHI-PROJECT-17K07158, KAKENHI-PROJECT-17K08977, KAKENHI-PROJECT-16H06648, KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592, KAKENHI-PROJECT-17J02206
  • [Journal Article] Protective role of testis-specific peroxiredoxin 4 against cellular oxidative stress.2017

    • Author(s)
      Eisuke Tasaka, Shotaro Matsumoto, Hisashi Tada, Toshihiro Kurahashi, Xuhong Zhang, Junichi Fujii, Toshihiko Utsumi, Yoshihito Iuchi
    • Journal Title

      J Clin Biochem Nutr

      Volume: in press

    • NAID

      130005632009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Journal Article] The viability of primary hepatocytes is maintained under a low cysteine-glutathione redox state with a marked elevation in ophthalmic acid production.2017

    • Author(s)
      Lee, J., Kang, E. S., Kobayashi, S., Homma, T., Sato, H., Seo, H. G., and Fujii, J.
    • Journal Title

      Exp Cell Res

      Volume: 361 Pages: 178-191

    • DOI

      10.1016/j.yexcr.2017.10.017

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K01829, KAKENHI-PROJECT-17K07158, KAKENHI-PROJECT-17K08977, KAKENHI-PROJECT-16H06648, KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
  • [Journal Article] xCT deficiency aggravates acetaminophen-induced hepatotoxicity under inhibition of the transsulfuration pathway.2017

    • Author(s)
      Eun Sil Kang, Jaeyong Lee, Takujiro Homma, Toshihiro Kurahashi, Sho Kobayashi, Atsunori Nabeshima, Sohsuke Yamada, Han GeuK Seo, Satoshi Miyata, Hideyo Sato, Junichi Fujii
    • Journal Title

      Free Radic. Res.

      Volume: 51 Pages: 80-90

    • DOI

      10.1080/10715762.2017.1282157

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06648, KAKENHI-PROJECT-16K16592, KAKENHI-PROJECT-16K01829, KAKENHI-PROJECT-17K07158, KAKENHI-PROJECT-17K08977, KAKENHI-PROJECT-15K08294
  • [Journal Article] Heightened aggressive behavior in mice deficient in aldo-keto reductase 1a (Akr1a)2017

    • Author(s)
      Takujiro Homma, Ryusuke Akihara, Satoshi Okano, Mototada Shichiri, Yasukazu Yoshida, Ken-ichi Yamada, Satoshi Miyata, Osamu Nakajima, Junichi Fujii
    • Journal Title

      Behav Brain Res

      Volume: 319 Pages: 219-224

    • DOI

      10.1016/j.bbr.2016.11.038

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K16592, KAKENHI-PROJECT-15K08294
  • [Journal Article] Protective role of testis-specific peroxiredoxin 4 against cellular oxidative stress2017

    • Author(s)
      Eisuke Tasaki, Shotaro Matsumoto, Hisashi Tada, Toshihiro Kurahashi, Xuhong Zhang, Junichi Fujii, Toshihiko Utsumi, Yoshihito Iuchi
    • Journal Title

      J. Clin. Biochem. Nutr.

      Volume: 60(3) Issue: 3 Pages: 156-161

    • DOI

      10.3164/jcbn.16-96

    • NAID

      130005632009

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26660113, KAKENHI-PROJECT-17K01365, KAKENHI-PROJECT-17K07758, KAKENHI-PROJECT-15K08294
  • [Journal Article] Increased ophthalmic acid production is supported by amino acid catabolism under fasting conditions in mice2017

    • Author(s)
      Sho Kobayashi, Jaeyong Lee, Toshifumi Takao, Junichi Fujii.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 491 Pages: 649-655

    • DOI

      10.1016/j.bbrc.2017.07.149

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06648, KAKENHI-PROJECT-15K08294
  • [Journal Article] Ascorbic acid prevents acetaminophen-induced hepatotoxicity in mice by ameliorating glutathione recovery and autophagy2017

    • Author(s)
      Kurahashi T, Lee J, Nabeshima A, Homma T, Kang ES, Saito Y, Yamada S, Nakayama T, Yamada K, Miyata S, Fujii J.
    • Journal Title

      Archives of Biochemistry and Biophysics

      Volume: 604 Pages: 1319-1333

    • DOI

      10.1016/j.abb.2016.06.004

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25870075, KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
  • [Journal Article] Mice in the early stage of liver steatosis caused by a high fat diet are resistant to thioacetamide-induced hepatotoxicity and oxidative stress2017

    • Author(s)
      Lee Jaeyong、Homma Takujiro、Fujii Junichi
    • Journal Title

      Toxicology Letters

      Volume: 277 Pages: 92-103

    • DOI

      10.1016/j.toxlet.2017.06.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
  • [Journal Article] A high-fat diet temporarily renders Sod1-deficient mice resistant to an oxidative insult2017

    • Author(s)
      Junitsu Ito, Naoki Ishii, Ryusuke Akihara, Jaeyong Lee, Toshihiro Kurahashi, Takujiro Homma, Ryo Kawasaki, Junichi Fujii
    • Journal Title

      J Nutr Biochem

      Volume: 40 Pages: 44-52

    • DOI

      10.1016/j.jnutbio.2016.10.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K16592, KAKENHI-PROJECT-15K08294
  • [Journal Article] Trichloroethylene exposure aggravates behavioral abnormalities in mice that are deficient in superoxide dismutase2016

    • Author(s)
      Otsuki N, Homma T, Fujiwara H, Kaneko K, Hozumi Y, Shichiri M, Takashima M, Ito J, Konno T, Kurahashi T, Yoshida Y, Goto K, Fujii S, Fujii J.
    • Journal Title

      Regulatory Toxicology and Pharmacology

      Volume: 79 Pages: 83-90

    • DOI

      10.1016/j.yrtph.2016.05.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25870075, KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
  • [Journal Article] Heat stress promotes the down-regulation of IRE1α in cells: An atypical modulation of the UPR pathway.2016

    • Author(s)
      Takujiro Homma, Junichi Fujii
    • Journal Title

      Experimental Cell Research

      Volume: 349 Pages: 128-138

    • DOI

      10.1016/j.yexcr.2016.10.006

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
  • [Journal Article] Characteristics of Skeletal Muscle Fibers of SOD1 Knockout Mice2016

    • Author(s)
      Hiroshi Nagahisa, Kazuma Okabe, Yoshihito Iuchi, Junichi Fujii, Hirofumi Miyata.
    • Journal Title

      Oxidative Medicine and Cellular Longevity

      Volume: 9345970 Pages: 9345970-9345970

    • DOI

      10.1155/2016/9345970

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-15K12681
  • [Journal Article] Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease2016

    • Author(s)
      Aya Nawata, Hirotsugu Noguchi, Yuichi Mazaki, Toshihiro Kurahashi, Atsunori Nabeshima, Ke-Yong Wang, Satoshi Kimura, Hidetaka Uramoto, Kimitoshi Kohno, Hatsumi Taniguchi, Yoshiya Tanaka, Junichi Fujii, Yasuyuki Sasaguri Toshiyuki Nakayama, and Sohsuke Yamada.
    • Journal Title

      PLoS One

      Volume: e0152549

    • DOI

      10.1371/journal.pone.0152549

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-25440051, KAKENHI-PROJECT-25870075, KAKENHI-PROJECT-16K08750
  • [Journal Article] The SOD1 transgene expressed in erythroid cells alleviates fatal phenotype in congenic NZB/NZW-F1 mice.2016

    • Author(s)
      Noriyuki Otsuki, Tasuku Konno, Toshihiro Kurahashi, Saori Suzuki, Jaeyong Lee, Futoshi Okada, Yoshihito Iuchi, Takujiro Homma, Junichi Fujii
    • Journal Title

      Free Radic Res

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Journal Article] Ablation of aldehyde reductase aggravates carbon tetrachloride-induced acute hepatic injury involving oxidative stress and endoplasmic reticulum stress.2016

    • Author(s)
      Ryusuke Akihara, Takujiro Homma, Jaeyong Lee, Ken-ichi Yamada, Satoshi Miyata, Junichi Fujii
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 478 Pages: 765-771

    • DOI

      10.1016/j.bbrc.2016.08.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
  • [Journal Article] The SOD1 transgene expressed in erythroid cells alleviates fatal phenotype in congenic NZB/NZW-F1 mice2016

    • Author(s)
      Otsuki N, Konno T, Kurahashi T, Suzuki S, Lee J, Okada F, Iuchi Y, Homma T, Fujii J.
    • Journal Title

      Free Radical Research

      Volume: 50 Pages: 793-800

    • DOI

      10.1080/10715762.2016.1178388

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25870075, KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-16K16592
  • [Journal Article] Application of glutathione as anti-oxidative and anti-aging drug.2015

    • Author(s)
      Takujiro Homma, Junichi Fujii
    • Journal Title

      Curr Drug Metab

      Volume: 16 Pages: 560-571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Journal Article] An SOD1 deficiency enhances lipid droplet accumulation in the fasted mouse liver by aborting lipophagy2015

    • Author(s)
      Toshihiro Kurahashi, Shinji Hamashima, Takaya Shirato, Jaeyong Lee, Takujiro Homma, Eun Sil Kang, Junichi Fujii.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 467 Pages: 866-871

    • DOI

      10.1016/j.bbrc.2015.10.052

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-25870075
  • [Journal Article] Physiological and Pathological Views of Prdx4.2015

    • Author(s)
      Junichi Fujii, Yoshitaka Ikeda, Toshihiro Kurahashi, Takujiro Homma
    • Journal Title

      Free Radic. Biol. Med

      Volume: 83 Pages: 373-379

    • DOI

      10.1016/j.freeradbiomed.2015.01.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Journal Article] Oxidative stress triggers lipid droplet accumulation in primary cultured hepatocytes by activating fatty acid synthesis2015

    • Author(s)
      Jaeyong Lee, Takujiro Homma, Toshihiro Kurahashi, Eun Sil Kang, andJunichi Fujii.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 464 Pages: 229-235

    • DOI

      10.1016/j.bbrc.2015.06.121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-25870075
  • [Journal Article] Roles of Antioxidative Enzymes in Wound Healing2015

    • Author(s)
      Toshihiro Kurahashi, Junichi Fujii.
    • Journal Title

      J Dev Biol

      Volume: 3 Pages: 57-70

    • DOI

      10.3390/jdb3020057

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Journal Article] Oxidative stress as a potential causal factor for autoimmune hemolytic anemia and systemic lupus erythematosus2015

    • Author(s)
      Junichi Fujii, Toshihiro Kurahashi, Tasuku Konno, Takujiro Homma, Yoshihito Iuchi
    • Journal Title

      World J Nephrol

      Volume: 4 Pages: 213-222

    • DOI

      10.5527/wjn.v4.i2.213

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Journal Article] Cystathionine is a novel substrate ofcystine/glutamate transporter: implications forimmune function.2015

    • Author(s)
      Kobayashi, S., Sato, M., Kasakoshi, T., Tsutsui, T., Sugimoto, M., Osaki, M., Okada, F., Igarashi, K., Hiratake, J., Homma, T., Conrad, M., Fujii, J., Soga, T., Bannai, S., Sato, H.
    • Journal Title

      J Biol Chem.

      Volume: 290 Pages: 8778-8788

    • DOI

      10.1074/jbc.m114.625053

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22134007, KAKENHI-PROJECT-24500967, KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-26460472, KAKENHI-PROJECT-26462860
  • [Journal Article] SOD1 deficiency decreases proteasomal function, leading to the accumulation of ubiquitinated proteins in erythrocytes2015

    • Author(s)
      Takujiro Homma, Toshihiro Kurahashi, Jaeyong Lee, Eun Sil Kang and Junichi Fujii
    • Journal Title

      Arch Biochem Biophys

      Volume: 583 Pages: 65-72

    • DOI

      10.1016/j.abb.2015.07.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-25870075
  • [Journal Article] SOD1 deficiency induces the systemic hyperoxidation of peroxiredoxin in the mouse2015

    • Author(s)
      Takujiro Homma, Satoshi Okano, Jaeyong Lee, Junitsu Ito, Noriyuki Otsuki, Toshihiro Kurahashi, Eun Sil Kang, Osamu Nakajima, and Junichi Fujii
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 463 Pages: 1040-1046

    • DOI

      10.1016/j.bbrc.2015.06.055

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08294, KAKENHI-PROJECT-25870075
  • [Journal Article] Ascorbic acid reverses the prolonged anesthetic action of pentobarbital in Akr1a-knockoutmice2014

    • Author(s)
      Junitsu Ito a,Noriyuki Otsuki a, Xuhong Zhang a, Tasuku Konno a, Toshihiro Kurahashi a,Motoko Takahashi b, Mayumi YamaKen-ichi Yamada d, Satoshi Miyata e, Junichi Fujiito c,YutaMatsuoka d,
    • Journal Title

      Life Sciences

      Volume: 95 Pages: 1-8

    • DOI

      10.1016/j.lfs.2013.12.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25870075
  • [Journal Article] Kidney fi brosis is independent of the amount of ascorbic acid in mice with unilateral ureteral obstruction2014

    • Author(s)
      Nishida H, Kurahashi T, Saito Y, Otsuki N, Kwon M, Ohtake H H, Yamakawa M, Yamada K, Miyata S, Tomita Y, Fujiia J
    • Journal Title

      Free Radical Research

      Volume: 48 Pages: 1115-1124

    • DOI

      10.3109/10715762.2014.915031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460451, KAKENHI-PROJECT-25870075
  • [Journal Article] Reductive detoxification of acrolein as a potential role for aldehyde reductase (AKR1A) in mammals.2014

    • Author(s)
      Toshihiro Kurahashi a, Myoungsu Kwona, Takujiro Hommaa, Yuka Saito a, Jaeyong Lee a, Motoko Takahashi b, Ken-ichi Yamadac, Satoshi Miyata d, Junichi Fujii
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 452 Pages: 136-141

    • DOI

      10.1016/j.bbrc.2014.08.072

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25870075, KAKENHI-PROJECT-26440058
  • [Journal Article] Oxidative stress and redox regulation of gametogenesis, fertilization, and embryonic development2014

    • Author(s)
      Tsunoda S, K, Kimura N and Fujii J
    • Journal Title

      Reproductive Medicine and Biology

      Volume: 13 Pages: 71-79

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Journal Article] Differential responses of SOD1-deficient mouse embryonic fibroblasts to oxygen concentrations.2013

    • Author(s)
      Tsunoda S, Kibe N, Kurahashi T, and Fujii J.
    • Journal Title

      Arch. Biochem. Biophys.

      Volume: 537 Pages: 5-11

    • DOI

      10.1016/j.abb.2013.06.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25870075
  • [Journal Article] Impaired fertilizing ability of Sod1-deficient mouse sperm during in-vitro fertilization2012

    • Author(s)
      Tsunoda Satoshi, Kawano Natsuko, Miyado Kenji, Kim ura Naoko, Fujii Junichi.
    • Journal Title

      Biol Reprod

      Volume: 87 Pages: 121-121

    • DOI

      10.1095/biolreprod.112.102129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J56123, KAKENHI-PLANNED-21112006, KAKENHI-PROJECT-22590262, KAKENHI-PROJECT-23659788
  • [Journal Article] 細胞増殖に関わるリン酸化・脱リン酸化の制御における活性酸素種のシグナル伝達分子としての役割2012

    • Author(s)
      藤井順逸
    • Journal Title

      Vitamemebrane

      Volume: 12 Pages: 1-9

    • Data Source
      KAKENHI-PROJECT-22590262
  • [Journal Article] 細胞内外で多様な機能を発揮するレドックス分子・ぺルオキシレドキシン-42012

    • Author(s)
      藤井順逸
    • Journal Title

      日本応用酵素協会誌

      Volume: 47 Pages: 19-27

    • Data Source
      KAKENHI-PROJECT-22590262
  • [Journal Article] Impaired fertilizing ability of Sod1-deficient mouse sperm during in-vitro fertilization2012

    • Author(s)
      Tsunoda S, Kawano N, Miyado K, Kimura N, Fujii J.
    • Journal Title

      Biology of Reproduction

      Volume: 87 Pages: 106-106

    • DOI

      10.1007/978-3-642-30018-9_108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Journal Article] A malfunction in the triglyceride transfer from the intracellular lipid pool to the apoB in the enterocytes of SOD1-deficient mice2012

    • Author(s)
      Kurahashi Toshihiro, Konno Tasuku, Otsuki Noriyuki, Kwon Myoungsu, Tsunoda Satoshi, Ito Junitsu, Fujii Junichi
    • Journal Title

      FEBS Lett

      Volume: 586 Pages: 4289-4295

    • DOI

      10.1016/j.febslet.2012.09.047

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J56123, KAKENHI-PROJECT-22590262
  • [Journal Article] Measurement of Peroxiredoxin-4 in Rat Tissues and Implication of Its Serum Levels as a Potential Marker for Hepatic Disease2012

    • Author(s)
      Ritsu Ito, Motoko Takahashi, Hideyuki Ihara, Hiroki Tsukamoto, Junichi Fujii, Yoshitaka Ikeda
    • Journal Title

      Mol Med Report

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Journal Article] Endoplasmic reticulum thiol oxidase deficiency leads to ascorbic acid depletion and noncanonical scurvy in mice2012

    • Author(s)
      Ester Zito, Henning Gram Hansen, Giles S. H. Yeo, Junichi Fujii, and David Ron.
    • Journal Title

      Mol Cell

      Volume: 48 Pages: 39-51

    • DOI

      10.1016/j.molcel.2012.08.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Journal Article] 酸化ストレスと女性生殖機能-活性酸素のもつ細胞内シグナルとしての役割2012

    • Author(s)
      藤井順逸
    • Journal Title

      Hormone Frontier in Gynecology

      Volume: 19 Pages: 143-147

    • Data Source
      KAKENHI-PROJECT-22590262
  • [Journal Article] Peroxiredoxin-controlled G-CSF signalling at the endoplasmic reticulum-early end osome interface2011

    • Author(s)
      Karishma Palande, Onno Roovers, Judith Gits, Carola Verwijmeren, Yoshihito Iuchi, Junichi Fujii, Benjamin G Neel, Robert Karisch, Jan Tavernier, and Ivo P Touw
    • Journal Title

      J Cell Sci

      Volume: 124 Pages: 3695-3705

    • DOI

      10.1242/jcs.089656

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Journal Article] Introduction to serial reviews: physiological relevance of antioxid/redox genes; learning from genetically modified animals2011

    • Author(s)
      Junichi Fujii
    • Journal Title

      J. Clin. Biochem. Nutr.

      Volume: 49 Issue: 2 Pages: 69-69

    • DOI

      10.3164/jcbn.10-138srint

      10.3164/jcbn.10-138SRInt

    • NAID

      130004466648

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Journal Article] Development of a quantitative bioassay to assess preventive compounds against inflammation-based carcinogenesis2011

    • Author(s)
      Kunishige Onuma, Yuka Suenaga, Ryuta Sakaki, Satoshi Yoshitome, Yu Sato, Satomi Ogawara, Saori Suzuki, Mitsuhiro Kuramitsu, Hidekatsu Yokoyama, Akira Murakami, Junichi Hamada, Garth L Nicolson, Masanobu Kobayashi, Junichi Fujii, Futoshi Okada
    • Journal Title

      Nitric Oxide

      Volume: 25 Pages: 183-194

    • DOI

      10.1016/j.niox.2011.02.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590262, KAKENHI-PROJECT-23590461
  • [Journal Article] Redox regulation of spermatogenic process and fertilisation2011

    • Author(s)
      Junichi Fujii, Satoshi Tsunoda
    • Journal Title

      Asian J Androl

      Volume: VOL.13 Pages: 420-423

    • DOI

      10.1038/aja.2011.10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J56123, KAKENHI-PROJECT-22590262
  • [Journal Article] Different consequences of the reactions with hydrogen peroxide and t-butyl hydro peroxide in the hyperoxidative inactivation of rat peroxiredoxin-42011

    • Author(s)
      Yoshitaka Ikeda, Miyako Nakano, Hideyuki Ihara, Ritsu Ito, Naoyuki Taniguchi, Junichi Fujii
    • Journal Title

      J Biochem

      Volume: 149 Pages: 443-453

    • DOI

      10.1093/jb/mvq156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Journal Article] Identification and characterization of an alternatively transcribed form of peroxir edoxin IV that is specifically expressed in spermatids of the postpubertal mouse testis2011

    • Author(s)
      Sun Hee Yim, Yoo-Jin Kim, Sue Young Oh, Junichi Fujii, Yan Zhang, Vadim N. Gladyshev, and Sue Goo Rhee
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 39002-39012

    • DOI

      10.1074/jbc.m111.257220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Journal Article] Unveiling the roles of the glutathione redox system <i>in vivo</i> by analyzing genetically modified mice2011

    • Author(s)
      Junichi Fujii, Jun-itsu Ito, Xuhong Zhang, Toshihiro Kurahashi
    • Journal Title

      J. Clin. Biochem. Nutr.

      Volume: 49 Issue: 2 Pages: 70-78

    • DOI

      10.3164/jcbn.10-138sr

      10.3164/jcbn.10-138SR

    • NAID

      130004466649

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Journal Article]2011

    • Author(s)
      Fujii, Junichi
    • Journal Title

      J CIin Biochem Nutr

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Journal Article] Implication of oxidative stress as a cause of autoimmune hemolytic anemia in the NZB mice2010

    • Author(s)
      Yoshihito Iuchi, Noriko Kibe, Satoshi Tsunoda, Saori Suzuki, Takeshi Mikami, Futoshi Okada, Koji Uchida, and Junichi Fujii
    • Journal Title

      Free. Radic. Biol. Med.

      Volume: 48 Pages: 935-944

    • DOI

      10.1016/j.freeradbiomed.2010.01.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Journal Article] Intrinsic oxidativestress causes either two-cell arrest or cell death depending on developmental stage of the embryo from SOD1-deficient mice2010

    • Author(s)
      Naoko Kimura, Satoshi Tsunoda, Yoshihito Iuchi, Hiroyuki Abe, Kiyoshi Totsukawa, and Junichi Fujii
    • Journal Title

      Mol. Hum. Reprod

      Volume: 16 Pages: 441-451

    • DOI

      10.1093/molehr/gaq007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Journal Article] Identification of a lipid peroxidation product as the source of oxidation-specific epitopes recognized by anti-DNA autoantibodies2010

    • Author(s)
      Otaki, N., Chikazawa, M., Nagae, R., Shimozu, Y., Shibata, T., Ito, S., Takasaki, Y., Fujii, J., and Uchida, K.
    • Journal Title

      J Biol Chem

      Volume: 285 Pages: 33834-33842

    • DOI

      10.1074/jbc.m110.165175

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117007, KAKENHI-PROJECT-21248016, KAKENHI-PROJECT-22590262
  • [Journal Article] B to plasma cell terminal differentiation entails oxidative stress and profound reshaping of the antioxidant responses2010

    • Author(s)
      Milena Bertolotti, Sun Hee Yim, Jose M. Garcia-Manteiga, Silvia Masciarelli, Yoo-Jin Kim, Min-Hee Kang, Yoshihito Iuchi, Junichi Fujii, Roberta Vene, Anna Rubartelli, Sue Goo Rhee, Roberto Sitia
    • Journal Title

      Antioxid Redox Signal

      Pages: 1133-1144

    • DOI

      10.1089/ars.2009.3079

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Journal Article] Molecular mechanisms of inflammation-induced carcinogenesis.2006

    • Author(s)
      Okada F, Fujii J
    • Journal Title

      J Clin Biochem Nutr 39

      Pages: 103-113

    • NAID

      130004879097

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590334
  • [Journal Article] Molecular mechanisms of inflammation-induced carcinogenesis.2006

    • Author(s)
      Okada F, Fujii J
    • Journal Title

      J Clin Biochem Nutr 39

      Pages: 103-113

    • NAID

      130004879097

    • Data Source
      KAKENHI-PROJECT-18015006
  • [Journal Article] Prevention of tumor progression as the ultimate goal of cancel therapy.2005

    • Author(s)
      Okada F, Fujii J
    • Journal Title

      Cancer Therapy 3

      Pages: 219-226

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590334
  • [Journal Article] Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive system2005

    • Author(s)
      Fujii, J et al.
    • Journal Title

      Reprod Biol Endocrinol 3

      Pages: 43-52

    • Data Source
      KAKENHI-PROJECT-17590334
  • [Journal Article] Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive system.2005

    • Author(s)
      Fujii J et al.
    • Journal Title

      Reprod Biol Endocrinol 3

      Pages: 43-52

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590334
  • [Journal Article] Prevention of tumor progression as the ultimate goal of cancer therapy.2005

    • Author(s)
      Okada F, Fujii J
    • Journal Title

      Cancer Therapy 3

      Pages: 219-226

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590334
  • [Journal Article] Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive system2005

    • Author(s)
      Fujii, J et al.
    • Journal Title

      Reprod Biol Endocrinol 3

      Pages: 43-52

    • Data Source
      KAKENHI-PROJECT-17016007
  • [Journal Article] Mosby2005

    • Author(s)
      Junichi Fujii
    • Journal Title

      Medical Biochemistry 2^<nd> ed

      Pages: 12-12

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590238
  • [Journal Article] Augmented expression of peroxiredoxinVI in rat lung and kidney after birth implies an antioxidative role.2001

    • Author(s)
      Fujii, T. et al.
    • Journal Title

      Eur. J. Biochem. 268

      Pages: 218-224

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-10044286
  • [Journal Article] Augmented expression of peroxiredoxin VI in rat lung and kidney after birth implies an antioxidative role.2001

    • Author(s)
      Fujii, T. et al.
    • Journal Title

      Eur.J.Biochem. 268

      Pages: 218-224

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-10044286
  • [Journal Article] Redox capacity of cells affects inactivation of glutathione reductase by nitrosative stress.2000

    • Author(s)
      Fujii, T. et al.
    • Journal Title

      Archives of Biochemistry and Biophysics 378

      Pages: 123-130

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-10044286
  • [Journal Article] A defect in the mitochondrial import of mutant Min-superoxide dismutase produced in Sf21 cells.1998

    • Author(s)
      Fujii, J. et al.
    • Journal Title

      J.Biochem. 124

      Pages: 340-346

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-10044286
  • [Journal Article] A defect in the mitochondrial import of mutant Mn-superoxide dismutase produced in Sf21 cells.1998

    • Author(s)
      Fujii, J. et al.
    • Journal Title

      J.Biochem. 124

      Pages: 340-346

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-10044286
  • [Presentation] Prevention of diethylnitrosamine-induced hepatic injury and carcinogenesis in mice by vitamin C2020

    • Author(s)
      Ishii Naoki, Homma Takujiro, Fujii Junichi
    • Organizer
      th International Translational Cancer Research Conference:Role of Inflammation and Immune System for Cancer Prevention and Treatment
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] Oxidative stress as the causal factor for anemic diseases.2020

    • Author(s)
      Fujii J., Homma T., Kobayashi S., Warang P., Madkaikar M., Mukherjee M.B.
    • Organizer
      The Society for Free Radical Research (SFRR)-INDIA-2020
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] フリーラジカル消去剤エダラボンによるフェロトーシス抑制作用.2019

    • Author(s)
      本間拓二郎、小林翔、佐藤英世、藤井順逸.
    • Organizer
      第72回日本酸化ストレス学会
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] フェロトーシス抑制にみるシステイン-グルタチオン系の重要性.2019

    • Author(s)
      藤井順逸
    • Organizer
      Free Radical School 2019 in Uonuma
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] Oxidative stress aggravates proteasome inhibitor bortezomib-induced proteotoxicity in mice.2019

    • Author(s)
      Homma Takujiro, Ishii Naoki, Kobayashi Sho, Fujii Junichi .
    • Organizer
      9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] Aldehyde reductase (Ak1a)ノックアウトマウスの発育障害ならびに発癌剤感受性に関する検討.2019

    • Author(s)
      石井直樹、本間拓二郎、小林翔、藤井順逸
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] Carnosine dipeptidase 2 (CNDP2) as a potential survival factor for xCT-deficient cells against ferroptosis.2019

    • Author(s)
      Kobayashi Sho, Homma Takujiro, Okumura Nobuaki, Takao Toshifumi, Sato Hideyo, Fujii Junichi
    • Organizer
      9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] Quantitative analysis of γ-glutamylpeptides by LC-MS and application for studying liver injury and γ-glutamyltransferase assay2019

    • Author(s)
      Fujii Junichi, Kobayashi Sho, Tokairin Yoshinori, Miyakoshi Takeru, Saito Takuya, Nagaoka Keita, Ikeda Yoshitaka, Konno Hiroyuki
    • Organizer
      9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] アルデヒド還元酵素(Akr1a)欠損マウスにおける持久力および運動時エネルギー代謝調節機構の解析2019

    • Author(s)
      高橋未来、本間拓二郎、小林翔、石井直樹、文潔、中島修、藤井順逸
    • Organizer
      日本生化学会東北支部第85回例会
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] エダラボンをはじめとする各種フリーラジカル消去剤によるフェロトーシス抑制作用.2019

    • Author(s)
      本間拓二郎、小林 翔、佐藤英世、藤井順逸
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] Amelioration of the reproductive ability of SOD1-deficient female mice by supplemented ascorbic acid and CoQ10.2019

    • Author(s)
      Ishii Naoki, Homma Takujiro, Lee Jaeyong, Mitsuhashi Hikaru,Yamada Ken-ichi, Kimura Naoko, Yamamoto Yorihiro, Fujii Junichi
    • Organizer
      9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] LC-MSによるgグルタミルペプチド類の定量解析と生体内でのgグルタミルペプチド類の産生経路に関する研究2019

    • Author(s)
      小林翔、文 潔、本間拓二郎、池田義孝、今野博行、藤井順逸
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] Cysteine-Glutathione Redox System Protective Against Ferroptosis.2019

    • Author(s)
      Fujii Junichi
    • Organizer
      9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] Oxidative stress triggers systemic organ disorders associated with impaired lipid catabolism in mice during fasting.2018

    • Author(s)
      Homma Takujiro, Lee Jaeyong, Kurahashi Toshihiro, Kobayashi Sho, Ishii Naoki, Fujii Junichi
    • Organizer
      第41回日本分子生物学会大会
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] アスコルビン酸合成不全(Akr1a欠損)マウスは高い持久力を示す.2018

    • Author(s)
      高橋未来、本間拓二郎、石井直樹、中島修、藤井順逸
    • Organizer
      第41回日本分子生物学会大会
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] Takujiro Homma (poster), Naoki Ishii, Sho Kobayashi, Han Geuk Seo, Junichi Fujii. Oxidative stress causes male infertility by triggering autoimmune response in mice with the NZW background.2018

    • Author(s)
      Homma Takujiro, Ishii Naoki, Kobayashi Sho, Seo Han Geuk, Fujii Junichi
    • Organizer
      INTERNATIONAL CELL DEATH SOCIETY Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] Hepatocytes are resistant to cysteine deficiency-induced ferroptosis due to recruitment of cysteine by the transsulfuration pathway.2018

    • Author(s)
      Fujii Junichi, Lee Jaeyong, Kobayashi Sho, Homma Takujiro, Kang Eun Sil, Sato Hideyo, Seo Han Geuk
    • Organizer
      INTERNATIONAL CELL DEATH SOCIETY Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] Macrophages from xCT-deficient mice survive under high oxidative stress caused by cysteine and glutathione insufficiency.2018

    • Author(s)
      Kobayashi Sho, Hamashima Shinji, Homma Takujiro, Seo Han Geuk, Sato Hideyo, Fujii Junichi
    • Organizer
      INTERNATIONAL CELL DEATH SOCIETY Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] アスコルビン酸合成不全(Akr1a欠損)マウスは高い持久力を示す.2018

    • Author(s)
      本間拓二郎、高橋未来、石井直樹、中島修、藤井順逸
    • Organizer
      第71回日本酸化ストレス学会
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] Cys取込みによるグルタチオン合成の制御とgmma-グルタミル化ペプチドの生成機構.2018

    • Author(s)
      藤井順逸、小林翔、本間拓二郎、池田義孝
    • Organizer
      第71回日本酸化ストレス学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] SOD1 haploinsufficiency exerts deleterious effects on the testis via activation of the autoimmune response in NZW mice.2018

    • Author(s)
      Homma Takujiro, Ishii Naoki, Fujii Junichi
    • Organizer
      19th Biannual Meeting of the Society for Free Radical Research International (SFRRI 2016)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] xCT遺伝子欠損マクロファージの生存を可能にする分子機構の解明.2018

    • Author(s)
      小林翔、本間拓二郎、奥村宜明、佐藤英世、高尾敏文、藤井順逸
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18K06948
  • [Presentation] CoQ10およびアスコルビン酸はSOD1欠損雌マウスの生殖機能を改善する2017

    • Author(s)
      石井直樹、本間拓二郎、李在勇、小林翔、三橋輝、木村直子、山本順寛、藤井順逸
    • Organizer
      第70回日本酸化ストレス学会
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] Macrophages from xCT-deficient mice survive under low cysteine/glutathione redox conditions with high oxidative stress.2017

    • Author(s)
      Sho Kobayashi , Shinji Hamashima, Takujiro Homma, Junichi Fujii, Hideyo Sato
    • Organizer
      OCC World Congress 2017 and Annual SFRR-E Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06648
  • [Presentation] マクロファージの酸化ストレス防御とNO産生におけるシスチン・グルタミン酸トランスポーターの役割2017

    • Author(s)
      小林翔、浜島真司、本間拓二郎、藤井順逸、佐藤英世
    • Organizer
      第17回日本NO学会
    • Data Source
      KAKENHI-PROJECT-16H06648
  • [Presentation] マクロファージの酸化ストレス防御とNO産生におけるシスチン・グルタミン酸トランスポーターの役割2017

    • Author(s)
      小林翔、浜島真司、本間拓二郎、藤井順逸、佐藤英世
    • Organizer
      第17回日本NO学会
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] CoQ10 and ascorbic acid ameliorate reproductive ability of SOD1-deficient female mice2017

    • Author(s)
      Fujii Junichi, Ishii Naoki, Homma Takujiro, Lee Jaeyong, Kobayashi Sho, Mitsuhashi Hikaru, Kimura Naoko, Yamamoto Yorihiro
    • Organizer
      The 8th Joint Meeting of Society for Free Radical Research Australasia and Japan with International Symposium on Coenzyme Q10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] シスチントランスポーター・xCT欠損マウスは雄性生殖能が低下する2017

    • Author(s)
      本間拓二郎、浜島真司、小林翔、倉橋敏裕、渡辺連、木村直子、佐藤英世、藤井順逸
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] 絶食によるアミノ酸代謝の亢進はオフタルミン酸合成を促進する2017

    • Author(s)
      小林翔、李在勇、高尾敏文、藤井順逸
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)
    • Data Source
      KAKENHI-PROJECT-16H06648
  • [Presentation] シスチントランスポーター・xCTの男性生殖能における役割の検討2017

    • Author(s)
      本間拓二郎、浜島真司、小林翔、倉橋敏裕、渡辺連、木村直子、佐藤英世、藤井順逸
    • Organizer
      第70回日本酸化ストレス学会
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] Production of ophthalmic acid by the glutathione-synthesizing pathway in mouse hepatocytes under cysteine insufficiency2017

    • Author(s)
      Lee Jaeyong, Kobayashi Sho, Homma Takujiro, Kang Eun Sil, Sato Hideyo, Seo Han Geuk, Takao Toshifumi, Fujii Junichi
    • Organizer
      The 8th Joint Meeting of Society for Free Radical Research Australasia and Japan with International Symposium on Coenzyme Q10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] xCT欠損によりグルタチオン・レドックスバランスに障害のあるマクロファージの細胞培養系における性質2017

    • Author(s)
      小林翔、浜島真司、本間拓二郎、佐藤英世、藤井順逸
    • Organizer
      日本生化学会東北支部第83回例会
    • Data Source
      KAKENHI-PROJECT-16H06648
  • [Presentation] 絶食によるアミノ酸代謝の亢進はオフタルミン酸合成を促進する2017

    • Author(s)
      小林翔、李在勇、高尾敏文、藤井順逸
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] Macrophages from xCT-deficient mice survive under low cysteine/glutathione redox conditions with high oxidative stress2017

    • Author(s)
      Kobayashi Sho , Hamashima Shinji , Takujiro Homma,Fujii Junichi, Sato Hideyo
    • Organizer
      OCC World Congress 2017 and Annual SFRR-E Conference; METABOLIC STRESS AND REDOX REGULATION
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] Heterozygous SOD1 deficiency causes male infertility by triggering autoimmune response in mice with the NZW background2017

    • Author(s)
      Homma Takujiro, Ishii Naoki, Kobayashi Sho, Junichi Fujii
    • Organizer
      The 8th Joint Meeting of Society for Free Radical Research Australasia and Japan with International Symposium on Coenzyme Q10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] SOD1-knockout mice are resistant to lethal effects of thioacetamide-induced hepatotoxicity2016

    • Author(s)
      Takujiro Homma, Takaya Shirato, Jaeyong Lee, Toshihiro Kurahashi, Junichi Fujii
    • Organizer
      The 23rd Annual Meeting, a joint meeting with the Society for Free Radical Research International (SfRBM/SFRRI 2016)
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2016-11-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] アルデヒド還元酵素(AKR1a)欠損は四塩化炭素誘発脂肪肝を悪化させる2016

    • Author(s)
      明原隆介、本間拓二郎、李在勇、宮田哲、藤井順逸
    • Organizer
      第69回日本酸化ストレス学会
    • Place of Presentation
      仙台国際センター会議棟、仙台
    • Year and Date
      2016-08-30
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] SOD1欠損マウスの絶食による腎障害機構2016

    • Author(s)
      Lee Jaeyong、本間拓二郎、倉橋敏裕、姜恩實、藤井順逸
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター/東北大学川内キャンパス、仙台
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] SOD1欠損による酸化ストレスはシトクロムP450活性を抑制することで薬剤誘発性肝障害を軽減する2016

    • Author(s)
      本間拓二郎、白土貴也、李在勇、倉橋敏裕、藤井順逸
    • Organizer
      第69回日本酸化ストレス学会
    • Place of Presentation
      仙台国際センター会議棟、仙台
    • Year and Date
      2016-08-30
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] 肝臓へのシステイン供給におけるxCTとTranssulfuration経路の役割2016

    • Author(s)
      小林翔、姜恩實、李在勇、本間拓二郎、倉橋敏裕、徐漢克、佐藤英世、藤井順逸
    • Organizer
      第69回日本酸化ストレス学会
    • Place of Presentation
      仙台国際センター会議棟、仙台
    • Year and Date
      2016-08-30
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] 肝臓へのシステイン供給におけるxCTとTranssulfuration経路の役割2016

    • Author(s)
      小林翔、姜恩實、李在勇、本間拓二郎、倉橋敏裕、徐漢克、佐藤英世、藤井順逸
    • Organizer
      第69回日本酸化ストレス学会学術集会
    • Place of Presentation
      仙台国際センター会議棟、仙台市、宮城県
    • Year and Date
      2016-08-30
    • Data Source
      KAKENHI-PROJECT-16H06648
  • [Presentation] 一過性の脂肪蓄積はSOD1欠損マウスの肝臓を酸化ストレスから保護する2016

    • Author(s)
      石井直樹、伊藤純一、明原隆介、李在勇、倉橋敏裕、本間拓二郎、藤井順逸
    • Organizer
      第69回日本酸化ストレス学会
    • Place of Presentation
      仙台国際センター会議棟、仙台
    • Year and Date
      2016-08-30
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] Differential contribution of xCT and the transsulfuration pathway as cysteine-supply systems in hepatocytes2016

    • Author(s)
      Eun Sil Kang, Jaeyong Lee, Takujiro Homma, Sho Kobayashi, Toshihiro Kurahashi, Han Geuk Seo, Hideyo Sato, Junichi Fujii
    • Organizer
      The 9th International Conference on the Biology, Chemistry and Thrapeutic Applications of Nitric Oxide
    • Place of Presentation
      Sendai International Center, Sendai
    • Year and Date
      2016-05-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] 熱ストレス障害に対する小胞体ストレス応答の解析:酸化ストレスはIRE1発現を減少させる2016

    • Author(s)
      本間拓二郎、藤井順逸
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター/東北大学川内キャンパス、仙台
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] 薬剤性肝障害はSOD1欠損によりを軽減される2016

    • Author(s)
      白土貴也、本間拓二郎、李在勇、倉橋敏裕、藤井順逸
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター/東北大学川内キャンパス、仙台
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] 精子形成過程におけるシスチントランスポーター・xCTの生理的役割2016

    • Author(s)
      浜島真司、本間拓二郎、小林翔、倉橋敏裕、佐藤英世、藤井順逸
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター/東北大学川内キャンパス、仙台
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] アスコルビン酸によるアセトアミノフェン誘導性酸化ストレスからの肝臓保護作用2015

    • Author(s)
      倉橋敏裕、鍋島篤典、李在勇、本間拓二郎、山田壮亮、中山敏幸、宮田哲、藤井順逸
    • Organizer
      第68回日本酸化ストレス学会
    • Place of Presentation
      かごしま県民交流センター、鹿児島市、鹿児島県
    • Year and Date
      2015-06-11
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] Intrinsic oxidative stress induces accumulation of ubiquitinated and carbonylated proteins in mouse erythrocytes.2015

    • Author(s)
      Takujiro Homma, Junichi Fujii.
    • Organizer
      7th Joint Meeting of the Societies for Free Radical Research Australasia and Japan
    • Place of Presentation
      Christchurch, New Zealand
    • Year and Date
      2015-12-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] 酸化ストレスによる赤血球でのユビキチン・プロテアソーム系の破綻2015

    • Author(s)
      本間拓二郎、倉橋敏裕、藤井順逸
    • Organizer
      第68回日本酸化ストレス学会
    • Place of Presentation
      かごしま県民交流センター、鹿児島市、鹿児島県
    • Year and Date
      2015-06-11
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] 肝臓のシステイン・ホメオスタシスにおけるxCTとトランススルフレーション経路の役割2015

    • Author(s)
      姜恩實、李在勇、倉橋敏裕、本間拓二郎、小林翔、佐藤英世、藤井順逸
    • Organizer
      第15回日本NO学会
    • Place of Presentation
      千里ライフサイエンスセンター、吹田市、大阪府
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] ストレス応答で起こる脂肪蓄積は肝臓を障害から保護する2015

    • Author(s)
      李在勇、本間拓二郎、倉橋敏裕、姜恩實、藤井順逸
    • Organizer
      第88回日本生化学会・第38回日本分子生物学会合同大会
    • Place of Presentation
      神戸ポートアイランド、神戸市、兵庫県
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] アルデヒド還元酵素AKR1aは四塩化炭素による肝障害からの保護に重要である2015

    • Author(s)
      明原隆介、本間拓二郎、宮田哲、藤井順逸
    • Organizer
      第88回日本生化学会・第38回日本分子生物学会合同大会
    • Place of Presentation
      神戸ポートアイランド、神戸市、兵庫県
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] 薬剤性急性肝障害に対するアスコルビン酸の肝臓保護作用2015

    • Author(s)
      倉橋敏裕、鍋島篤典、齋藤由佳、李在勇、本間拓二郎、山田壮亮、中山敏幸、宮田哲、藤井 順逸
    • Organizer
      第81回 日本生化学会東北支部会
    • Place of Presentation
      東北大学、仙台市
    • Year and Date
      2015-05-19
    • Data Source
      KAKENHI-PROJECT-25870075
  • [Presentation] アスコルビン酸によるアセトアミノフェン誘導性酸化ストレスからの肝臓保護作用2015

    • Author(s)
      倉橋敏裕、鍋島篤典、李在勇、本間拓二郎、山田壮亮、中山敏幸、宮田哲、藤井 順逸
    • Organizer
      第68回 日本酸化ストレス学会学術集会
    • Place of Presentation
      かごしま県民交流センター、鹿児島市
    • Year and Date
      2015-06-11
    • Data Source
      KAKENHI-PROJECT-25870075
  • [Presentation] 酸化ストレスによるオートファジー障害に起因する脂質代謝障害2015

    • Author(s)
      倉橋敏裕、李在勇、白土貴也、浜島真司、本間拓二郎、白澤信行、藤井順逸
    • Organizer
      第88回日本生化学会・第38回日本分子生物学会合同大会
    • Place of Presentation
      神戸ポートアイランド、神戸市、兵庫県
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] 酸化ストレスによるオートファジー障害に起因する脂質代謝異常2015

    • Author(s)
      倉橋敏裕、李在勇、白土貴也、浜島真司、本間拓二郎、白澤信行、藤井 順逸
    • Organizer
      第38回 日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド、神戸市
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25870075
  • [Presentation] On the cysteine supply for glutathione synthesis in the liver under oxidative insult.2015

    • Author(s)
      Junichi Fujii, Toshihiro Kurahashi, Takujiro Homma, Jaeyong Lee, Eun Sil Kang, Shinji Hamashima, Atsunori Nabeshima, Sohsuke Yamada, Toshiyuki Nakayama, and Hideyo Sato.
    • Organizer
      7th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
    • Place of Presentation
      Chiang Mai, Thailand
    • Year and Date
      2015-11-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08294
  • [Presentation] The potential roles of PRDX4 as a thiol oxidase in endoplasmic reticulum.2014

    • Author(s)
      Toshihiro Kurahashi, Atsunori Nabeshima, Nobuyuki Shirasawa, Sohsuke Yamada, Junitsu Ito, Toshifumi Takao, and Junichi Fujii.
    • Organizer
      17th Biennial Meeting of Society for Free Radical Research International
    • Place of Presentation
      Kyoto International Conference Center, Kyoto, JAPAN
    • Data Source
      KAKENHI-PROJECT-25870075
  • [Presentation] 臓器の線維化における細胞外基質タンパク質の酸化的折畳み機構に関する研究2014

    • Author(s)
      倉橋敏裕、西田隼人、齋藤由香、李在勇、鍋島篤典、山田壮亮、 冨田善彦、宮田哲、高尾敏文、藤井順逸
    • Organizer
      生化学会東北支部会
    • Place of Presentation
      アキタパークホテル(秋田)
    • Year and Date
      2014-05-10
    • Data Source
      KAKENHI-PROJECT-25870075
  • [Presentation] 培養系卵の初期発生におけるビタミンCの役割~アルデヒド還元酵素遺伝子欠損卵を用いた検証~2013

    • Author(s)
      星野 由貴, 梅田 彩, 高橋 素子, 宮田 哲, 吉田 康一, 藤井 順逸, 木村 直子
    • Organizer
      第31回日本受精着床学会総会・学術講演会
    • Place of Presentation
      別府国際コンベンションセンター(別府市)
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Presentation] マウス初期胚発生におけるビタミンCの役割-活性持続型ビタミンCの効果-2013

    • Author(s)
      星野 由貴, 鈴木 あやめ, 吉田 康一, 藤井 順逸, 木村 直子
    • Organizer
      日本畜産学会第117回大会
    • Place of Presentation
      新潟大学(新潟市)
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Presentation] 老齢シスチン・グルタミン酸トランスポーター遺伝子欠損マウスにおける卵巣機能の解析2013

    • Author(s)
      渡辺 連, 角田 智志, 藤井 順逸, 佐藤 英世, 木村 直子
    • Organizer
      日本畜産学会第117回大会
    • Place of Presentation
      新潟大学(新潟市)
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Presentation] 老齢SOD1欠損マウスにおける排卵数減少の原因解明2013

    • Author(s)
      窪田 有里子, 藤井 順逸, 木村 直子
    • Organizer
      日本畜産学会第117回大会
    • Place of Presentation
      新潟大学(新潟市)
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Presentation] 体外成熟させたSOD1遺伝子欠損マウス卵でみられる異数性増加の解析2013

    • Author(s)
      名古 満, 藤井 順逸, 木村 直子
    • Organizer
      第54回日本卵子学会大会
    • Place of Presentation
      学術総合センター(東京都千代田区)
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Presentation] 酸化ストレスによる染色体異数性誘発卵における紡錘体形成チェックポイントタンパク質2013

    • Author(s)
      名古 満, 藤井 順逸, 木村 直子
    • Organizer
      第106回日本繁殖生物学会大会
    • Place of Presentation
      東京農工大学農学部府中キャンパス(府中市)
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Presentation] SOD1欠損による酸化的ストレスはPrdx4欠損マウスに肝障害を惹起する2013

    • Author(s)
      倉橋敏裕、李在勇、鍋島篤典、山田壮亮、白澤信行、伊藤純一、藤井 順逸
    • Organizer
      第36回日本分子生物学会
    • Place of Presentation
      神戸ポートアイランド、神戸
    • Data Source
      KAKENHI-PROJECT-25870075
  • [Presentation] Pleiotropic roles of Peroxiredoxin 4 in Antioxidation, Signal Regulation and Oxidative Protein Folding.2013

    • Author(s)
      Toshihiro Kurahashi, Atsunori Nabeshima, Nobuyuki Shirasawa, Sohsuke Yamada, Junitsu Ito, Toshifumi Takao, and Junichi Fujii.
    • Organizer
      6th Joint Meeting of the SFRR Australasia and Japan
    • Place of Presentation
      Mercure Sydney Hotel, Sydney, Autralia
    • Invited
    • Data Source
      KAKENHI-PROJECT-25870075
  • [Presentation] Roles of Peroxiredoxin 4 in ROS Signaling, Oxidative Protein Folding in ER, and Spermatogenesis2012

    • Author(s)
      Junichi Fujii (invited speaker)
    • Organizer
      UK-Japan Research Symposium; Molecular Mechanisms of Stress Response in Disease
    • Place of Presentation
      Tsukuba University, Ibaraki
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] SOD1欠損マウスにおける加齢による排卵卵子数および卵胞数の変化2012

    • Author(s)
      窪田 有里子, 猪野 友香里, 藤井 順逸, 木村 直子
    • Organizer
      第105回日本繁殖生物学会大会
    • Place of Presentation
      筑波大学大学会館 (つくば市)
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Presentation] Roles of Peroxiredoxin 4 in ROS Signaling, Oxidative Protein Folding in ER, and Spermatogenesis2012

    • Author(s)
      Junichi Fujii
    • Organizer
      UK-Japan Research Symposium; Molecular Mechanisms of Stress Response in Disease
    • Place of Presentation
      筑波大学(茨城県)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] Oxidative stress as a cause for autoimmune hemolytic anemia; supporting evidences from genetically modified mice2012

    • Author(s)
      Junichi Fujii
    • Organizer
      16th Biennial Meeting of the Society for Free Radical Research International
    • Place of Presentation
      ロンドン大学キングスカレッジ(ロンドン・英国)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] マウス卵初期発生過程におけるアスコルビン酸(VC)含量とVC合成系・取込み系遺伝子の発現2012

    • Author(s)
      星野 由貴, 樋口 謙太, 梅田 彩, 高橋 素子, 宮田 哲, 吉田 康一, 藤井 順逸, 木村 直子
    • Organizer
      第105回日本繁殖生物学会大会
    • Place of Presentation
      筑波大学大学会館 (つくば市)
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Presentation] マウス卵成熟過程でのSOD1欠損による受精障害の解析2012

    • Author(s)
      名古 満, 佐藤 康子, 角田 智志, 藤井 順逸, 木村 直子
    • Organizer
      第30回日本受精着床学会総会・学術講演会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Presentation] 炎症発癌を標的とした予防化合物の定量的検出系の開発2011

    • Author(s)
      末永裕佳、坂木隆太、小沼邦重、村上明、田中宏樹、浜田淳一、小林正伸、藤井順逸、岡田太
    • Organizer
      第70回日本癌学会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] 酸化還元酵素アルデヒドレダクターゼノックアウトマウスで発症するアスコルビン酸欠乏症とその影響2011

    • Author(s)
      高橋素子、宮田哲、藤井順逸、井内陽子、上山茂充、曽我朋義、藤縄玲子、荒木素子、谷口直之、黒木由夫
    • Organizer
      第64回日本酸化ストレス学会
    • Place of Presentation
      ルスツリゾートホテル・コンベンション(ルスツ,北海道)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] Roles of peroxiredoxin 4 in protein sulfhyryl oxidation2011

    • Author(s)
      Toshihiro Kurahashi, Chihiro Awada. Tasuku Konno, Noriyuki Otsuki, Satoshi Tsunoda, Xuhong Zhang, Junitsu Ito, Yoshihito Iuchi, Toshifumi Takao, Junichi Fujii
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] Peroxiredoxin 4 is a multifunctional redox protein working in endoplasmic reticulum and cytoplasm2011

    • Author(s)
      Junichi Fujii (poster), Yoshihito Iuchi, Xuhong Zhang, Satoshi Tsunoda, and Yoshitaka Ikeda
    • Organizer
      International Symposium on Free Radical Research: Contribution to Medicine (FRCM2011)
    • Place of Presentation
      Iburikawa, Kyoto
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] 赤血球を酸化ストレスによるレドックスバランスの破綻から護る抗酸化機構2011

    • Author(s)
      藤井順逸(シンポジスト)
    • Organizer
      第64回日本酸化ストレス学会
    • Place of Presentation
      ルスツ、北海道
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] Roles of peroxiredoxin 4 in protein sulfhyryl oxidation2011

    • Author(s)
      Toshihiro Kurahashi, Chihiro Awada, Tasuku Konno, Noriyuki Otsuki, Satoshi Tsunoda, Xuhong Zhang, Junitsu Ito, Yoshihito Iuchi, Toshifumi Takao, Junichi Fujii
    • Organizer
      5th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia), 8th Conference of Asian Society for Mitochondrial Research and Medicine (ASMRM)
    • Place of Presentation
      Kagoshima Citizens' Culture Hall (Kagoshima)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] SOD1欠損が雄性生殖能に与える影響2011

    • Author(s)
      角田智志、藤井順逸
    • Organizer
      第64回日本酸化ストレス学会
    • Place of Presentation
      ルスツリゾートホテル・コンベンション(ルスツ,北海道)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] Implication of oxidative stress as a cause of autoimmune hemolytic anemia2011

    • Author(s)
      Yoshihito Iuchi, Futoshi Okada, Junichi Fujii
    • Organizer
      Montreal, Modern Medical Forum 2011
    • Place of Presentation
      EPS Global Medical Development Inc.(Montreal, Canada)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] 過酸化PeoxiredoxinIIの検出による赤血球レドックスバランスと機能の解明2011

    • Author(s)
      伊藤純一、倉橋敏裕、金野祐、大槻倫之、角田智志、張旭紅、藤井順逸
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      国立京都国際会館(京都)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] Aldehyde reductase deficiency prolongs pentobarbital induced hypsosis in mice2011

    • Author(s)
      Junitsu Ito, Motoko Takahashi, Noriyuki Otsuki, Tasuku Konno, Hayato Nishida, Satoshi Tsunoda, Toshihiro Kurahashi, Xuhong Zhang, Satoshi Miyata, Junichi Fujii
    • Organizer
      4th Symposium on Nutrition, Oxygen Biology and Medicine
    • Place of Presentation
      Hotel de Seine (Paris, France)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] 内因性酸ストレス蓄積によマウス2細胞期発生停止へのCDKインヒビターの関与の可能性2011

    • Author(s)
      角田智志、木村直子、藤井順逸
    • Organizer
      第52回日本哺乳動物卵子学会
    • Place of Presentation
      国際医療福祉大学(大田原)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] NZマウスの自己免疫疾患発症に対する赤血球酸化名kストレスの関与2011

    • Author(s)
      金野祐、大槻倫之、鈴木紗織、岐部紀子、角田智志、井内良仁、藤井順逸
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      国立京都国際会館(京都)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] 赤血球を酸化ストレスによるレドックスバランスの破綻から護る抗酸化機構2011

    • Author(s)
      藤井順逸
    • Organizer
      第64回日本酸化ストレス学会
    • Place of Presentation
      ルスツリゾートホテル・コンベンション(ルスツ,北海道)(招待講演)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] Influences of the SOD1 deficiency on the gamete quality in in-vitro fertilization2011

    • Author(s)
      Satoshi Tsunoda, Naoko Kimura, Hiroyuki Abe, Akihiro Watanabe, Junichi Fujii
    • Organizer
      5th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia), 8th Conference of Asian Society for Mitochondrial Research and Medicine (ASMRM)
    • Place of Presentation
      Kagoshima Citizens' Culture Hall (Kagoshima)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] SOD1欠損マウス胎仔線維芽細胞を用いた酸化ストレス誘導性細胞周期停止機構の解析2011

    • Author(s)
      角田智志、岐部紀子、藤井順逸
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      国立京都国際会館(京都)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] 肝細胞癌におけるmiR-224の機能解析2011

    • Author(s)
      張旭紅、邵力、渡辺久剛、縢亮、齋藤貴史、石井里佳、横澤潤二、木村理、藤井順逸、深尾彰
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] 活性酸素のもつ二面性:生体傷害と細胞増殖・老化の制御2011

    • Author(s)
      藤井順逸
    • Organizer
      第12回Vitamemebrane研究会
    • Place of Presentation
      経団連会館(東京)(招待講演)
    • Year and Date
      2011-07-23
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] Peroxiredoxin 4 is a multifunctional redox protein working in endoplasmic reticulum and cytoplasm2011

    • Author(s)
      Fujii, Junichi
    • Organizer
      International Symposium on Free Radical Research
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] Prx4の抗酸化活性による活性酸素シグナルの制御2010

    • Author(s)
      藤井順逸(ワークショップ)
    • Organizer
      第33回日本分子生物学会第83回日本生化学合同年会
    • Place of Presentation
      神戸国際会議場、兵庫
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] SOD1欠損マウス胎児線維芽Prx4の抗酸化活性による活性酸素シグナルの制御2010

    • Author(s)
      藤井順逸
    • Organizer
      第33回日本分子生物学会第83回日本生化学合同年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] ベルオキシレドキシンによる抗酸化と活性酸素シグナルの制御2010

    • Author(s)
      藤井順逸
    • Organizer
      第27回臨床フリーラジカル会議
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22590262
  • [Presentation] 臓器線維化における細胞外基質蛋白質の酸化的折畳みに働く小胞体チオールオキシダーゼとアスコルビン酸に関する研究

    • Author(s)
      倉橋敏裕、西田隼人、齋藤由香、李在勇、鍋島篤典、山田壮亮、 冨田善彦、宮田哲、高尾敏文、藤井順逸
    • Organizer
      日本酸化ストレス学会
    • Place of Presentation
      同志社大学(京都)
    • Year and Date
      2014-09-04 – 2014-09-05
    • Data Source
      KAKENHI-PROJECT-25870075
  • [Presentation] The role of vitamin C in in vitro mouse early embryonic developmsent -the effects of supplementationof ascorbic acid 2-phosphate-

    • Author(s)
      Yuki Hoshino, Ren Watanabe, Koichi Yoshida,Junichi Fujii, Naoko Kimura
    • Organizer
      World Congress of Reproductive Biology 2014
    • Place of Presentation
      Edinburgh (Scotland)
    • Year and Date
      2014-09-02 – 2014-09-04
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Presentation] アセトアミノフェン急性肝障害におけるアスコルビン酸とチオール化合物の肝臓保護作用

    • Author(s)
      倉橋敏裕、鍋島篤典、齋藤由香、李在勇、本間拓二郎、山田壮亮、 中山敏幸、佐藤英世、宮田哲、藤井順逸
    • Organizer
      第37回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-25870075
  • [Presentation] Evaluation of oocyte quality and ovarian function in aged female cystine-glutamate transporter gene-deficient mice

    • Author(s)
      Ren Watanabe, Junichi Fujii, Hideyo Sato, Naoko Kimura
    • Organizer
      World Congress of Reproductive Biology 2014
    • Place of Presentation
      Edinburgh (Scotland)
    • Year and Date
      2014-09-02 – 2014-09-04
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Presentation] Intrinsic oxidative stress increases meiotic chromosome misalignment and aneuploidy in in vitro matured oocytes from SOD1-deficient mice

    • Author(s)
      Naoko Kimura, Mitsuru Nago, Kazuharu Odajima, and Junichi Fujii
    • Organizer
      World Congress of Reproductive Biology 2014
    • Place of Presentation
      Edinburgh (Scotland)
    • Year and Date
      2014-09-02 – 2014-09-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-24580405
  • [Presentation] MI期動原体へのBubR1の局在性低下が卵染色体の異数性を増加させる~成熟培養系SOD1遺伝子欠損マウス卵を用いた研究~

    • Author(s)
      名古 満, 藤井 順逸, 木村 直子
    • Organizer
      第32回日本受精着床学会総会・学術講演会
    • Place of Presentation
      ハイアットリージェンシー東京(東京都新宿区)
    • Year and Date
      2014-07-31 – 2014-08-01
    • Data Source
      KAKENHI-PROJECT-24580405
  • 1.  TANIGUCHI Naoyuki (90002188)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  SUZUKI Keiichiro (70221322)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  HIGASHIYAMA Shigeki (60202272)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  OKADA Futoshi (00250423)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 5.  CHUNG Mun Ok (60252657)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  Kurahashi Toshihiro (00596570)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 47 results
  • 7.  HOMMA Takujiro (70743566)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 52 results
  • 8.  KOBAYASHI Sho (10779490)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 34 results
  • 9.  YOSHIHITO Iuchi (60272069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 10.  KIMURA Naoko (70361277)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 18 results
  • 11.  SUGIYAMA Toshihiro (00127242)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  IHARA Yoshito (70263241)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KONDO Takahito (00158908)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TAKAHASHI Motoko (00303941)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 15.  SATO Hideyo (60235380)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 21 results
  • 16.  TAKAO Toshifumi (10197048)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 17.  葛巻 丈二朗 (70211208)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  泰地 真弘人 (10242025)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  CHOUVAEV Vladimir V
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  YAMAMOTO Hirotaka
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  DENNIS James W
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  DEUTSCH Harold F
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  ANDERSON Mary E
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  SIEST Gerard
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  SCHACHTER Harry
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  ITOH Satoru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  LEE Jaeyong
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 30 results
  • 28.  UCHIYAMA Kazuhiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  SATOH Kiyotoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  SUGIMOTO Masahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  TANIMOTO Akihide
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 32.  ONISHI Motoko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  ABE Hiroyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  SHIBATA Takahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  宮戸 健二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  東村 泰希
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  内藤 裕二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  高木 智久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  堅田 和弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  曽我 朋義
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  宮田 浩文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  真崎 雄一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  山田 壮亮
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 44.  山田 健一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 45.  内海 俊彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  山川 光徳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 47.  小林 孝安
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 48.  浦本 秀隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  石橋 浩晃
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 50.  内田 浩二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to connect your ORCID iD to this researcher?
* This action can be performed only by the researcher themselves.

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi