SUGIYAMA Toshihiro 杉山俊博

Researcher Number	00127242
Other IDs
Affiliation (based on the past Project Information) *help	2015: 秋田大学, 医学(系)研究科(研究院), 教授 2014: 秋田大学, その他部局等, 名誉教授 2014: 秋田大学, 医学部, 定年退職 2012 – 2013: 秋田大学, 医学(系)研究科(研究院), 教授 1992 – 2011: 1st Department of Biochemistry, Akita University School of Medicine, 医学部, 教授 … More 1992: 秋田大学, 医学部生化学, 教授 1987 – 1991: 大阪大学, 医学部, 助教授 1986: Associate Professor of Biochemistry, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Pathological medical chemistry / General medical chemistry / Biomedical engineering/Biological material science / Biomedical engineering/Biological material science / Digestive surgery Except Principal Investigator Surgical dentistry / General medical chemistry / Biological Sciences / Pediatrics / Applied health science / Pediatrics / 代謝生物化学
Keywords	Principal Investigator LECラット / oval cell / 肝癌 / 肝臓始原細胞 / 肝特異的転写因子 / 幹細胞 / 肝細胞 / 肝細胞転写因子 / 肝細胞分化 / 肝臓幹細胞 … More / 肝臓幹様細胞 / HNF-1 / EGF / 発生・分化 / ウイルソン病 / 肝炎 / 銅トランスポータ / DNA低メチル化 / 分化 / LEC ラット / レチノイン酸 / 肝・胆・膵 / 膵β細胞 / DNAメチル化 / Cytochrome P-450 / LEC rat / HNF-4 / 細胞移植 / 肝再生 / Shh / 劇症肝炎 / セルロプラスミン / 銅代謝酵素 / ゴルジ装置 / S-アデノシルメチオニン / c-myc / p53 / ウィルソン病 / PタイプATPase / 遺伝子治療 / 多分化能 / 肝臓 / 胆管 / 膵臓 / 発生・分化・再生 / 消化腺上皮 / ステムセル・バイオロジー / 再生医療 / 細胞工学 / 歯胚 / エナメル芽細胞 / 象牙芽細胞 / 歯再生 / 肝炎自然発症 / チトクロムPー450 / コリン欠乏食 / チトクロ-ムPー450 / Spontaneous hepatitis / DNA methylation / Choline-deficient diet / ウィルソン病モデル動物 / 肝薬物代謝酵素 / メチオニン代謝異常 / メチル基代謝 / Sーアデノシルメチオニン合成酵素 / グルタチオン / 肝細胞分画 / 肝炎モデル / 肝癌自然発症 / DNA hypomethylation / spontaneous hepatitis / hepatoma / drug metabolism / choline-deficient diet / Cytochrome P450 / Wilson's disease / 単鎖DNA / 抗ssDNA抗体 / アポトーシス / 発生 / DNAラダー / 癌化 / 単離DNA / apoptosis / ssDNA / single-stranded DNA / differentiation / development / antibody / carcinogenesis / HNFー1 / Oval cell / レチノイソ酸 / 肝転写因子 / HNF-3β / liver enriched transcription factors / oval cells / liver differentiation / liver stem cells / retinoic acid / コラーゲンゲル / コラーゲンスポンジ / 無アルブミンラット / 細胞分化 / 臓器再生 / 細胞移植治療 / 星細胞 / 不死化肝細胞 / 胆管上皮細胞 / 組織再生工学 / 人工肝臓構築 / Stem cell / Cell transplantation / Collagen gel / Collagen sponge / Analbuminemic rat / Cell differentiation / Organ regeneration / 再生医工学 / 培養表皮 / 間葉系幹細胞 / 骨・軟骨再生 / フィーダー細胞 / ケラチノサイト / 毛幹細胞 / 骨髄間葉系細胞 / 骨再生 / 毛再生 / 発毛促進 / Tissue Engineering / Liver regeneration / Stem Cells / Cultured skin / Mesenchyme / Bone regeneration / 増殖因子 / コラーゲン担体 / オンコスタチンM / HSL細胞 / 放線菌 / liver stem cell / growth factor / collagen / β-cell / oncostatin M / HSL cell / 脱ハロゲン化反応 / ハロセン / シトロクロム【b_5】 / シトロクロムP-450 / ラジカル / ジブロムエタン / debromination / cytochrome P-450 / cytochrome <b_5> / halothane / radical / dibromoethane / 薬物代謝酵素 / 自然発症肝癌 / シトクロムP-450 / 黄疸 / Drug Metabolizing Enzymes / Fluminant Hepatitis / Spontaneous Hepatoma / LEC Rat … More Except Principal Investigator LECラット / 肝癌 / 肝炎 / 銅代謝異常 / ウイルソン病 / 活性酸素 / 細胞移植 / グリケーション / Werner症候群 / セルロプラスミン / コラーゲン / 肝幹細胞 / 代謝性肝疾患 / 細胞分化 / 再生医学 / 歯学 / 歯の再生医療 / 間葉系幹細胞 / スーパーオキサイドディスムターゼ / 不活性化 / ウィルソン病 / Wilson's disease / glycation / active site liganding loop / Cu_1Znースーパーオキサイドディスムターゼ / Mnースーパーオキサイドディスムターゼ / 非酵素的糖化 / O^-_2 / 卵巣癌 / ELISA / 急性骨髄性白血病 / TNF / MnーSuperoxide Dismutase / Ovarian Cancer / Tumor marker / Tumor Necrosis Factor / Serum / 常染色体劣性遺伝 / 癌遺伝子 / D-penicillamine / メタロチオネイン / hts / ビタミンE / 肝炎hts遺伝子 / 活性酸素消去酵素 / HGF / プロモーション作用 / 肝がん / 発がんプロモーター / 高発がん遺伝子 / 酸化的DNA損傷 / がん抑制遺伝子 / 細胞周期チェックポイント調節因子 / ヒト肝がんモデル動物 / 肝臓幹様細胞 / 肝再生 / 骨髄 / パーコール密度勾配遠心 / 問葉系幹細胞 / 脂肪組織 / 歯の再生 / 移植・再生医療 / 口腔癌幹細胞 / Snail / 上皮間葉形質転換 / 浸潤 / 転移 / 免疫抑制 / 口腔癌 / 癌幹細胞 / マイクロバブル / ゼータ電位 / 気泡収縮 / 圧壊 / 動物実験 / 気力 / 気力回復 / シッフ塩基 / スーパーオキサイドデイスムターゼ / アデノウイルスベクター / 遺伝子治療 / ゴルジ装置 / 銅輸送P型ATPase / 銅輸送P型 ATPase / P-type ATPase / 組換えアデノウィルス / Adenoviral vector / Gene therapy / LEC rats / Golgi apparatus / Ceruloplasmin / Copper transporting P-type ATPase / ATP7B蛋白 / 細胞内銅輸送 / 酵母発現系 / △ccc2株 / Δccc2株 / ATP7B protein / Intracellular copper transport / Yeast expression system / the yeast Δccc2 strain / アルブミン / 無アルブミンラット / 肝上皮細胞 / 肝臓幹細胞 / α-フェトプロエイン / コラーゲンゲル / コラーゲンスポンジ / 肝星細胞 / Hepatic stem cell / Albumin / Collagen / Analbuminemic rat / Cell transplantation / Metabolic liver disease / Liver epithelial cell / Cell differentiation / ス-パ-オキサイドディスムタ-ゼ(SOD) / Enzyme-linked Immnosorbent Aassay法 / 網膜症 / Enzyme-linked Immunosorbent Assay / グリシト-ルリジン / superoxide dismutase / Cu,Zn-SOD / Enzyme-linked immunosorbent Assay / retinopathy Less

Elucidation of Microbubble Collapse Behavior and Its Application to Vitality
- Principal Investigator
  
  Hasegawa Hiroaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Utsunomiya University
  Akita University
Detection of oral cancer stem cell which indicates epithelial to mesenchymal transition and development of new cancer treatment that targeted oral cancer stem cell
- Principal Investigator
  
  NAKATA AKIRA
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Akita University
Development of tooth regenerative therapy applied molecular mechanisms of epithelial-mesenchymal interactions in tooth morphogenesis
- Principal Investigator
  
  NAGAI Hirokazu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokushima
Development of tooth regenerative therapy using the low crystalline carbonate apatite and mesenchymal stem cells derivedfrom adipose tissue
- Principal Investigator
  
  NAGAL Hirokazu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokushima
  Akita University
Development of the cell transplantation therapy for the tooth regeneration using the committed progenitor cell of the tooth established from the tooth germPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Toshihiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Akita University
骨髄からの肝幹細胞の分離と小児代謝性肝疾患に対する細胞移植治療
- Principal Investigator
  
  寺田邦彦
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Akita University
Search for facto s that induce transdifferentiation from liver stem cell to epitheial cells of digestive gland and development with tissue engineeringPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Toshihiro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Akita University
肝・胆・膵系ステムセル・バイオロジーと臓器再生医療への展開Principal Investigator
- Principal Investigator
  
  杉山俊博
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Akita University
Establishment of cell transplantation therapy for Wilson's disease using hepatic stem cells.
- Principal Investigator
  
  TERADA Kunihiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Akita University
肝臓幹様細胞の再生能を利用した肝癌に対する細胞移植治療法の開発
- Principal Investigator
  
  寺田邦彦
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University
肝特異的転写因子による肝臓幹様細胞(oval cell)の増殖・分化の制御機構Principal Investigator
- Principal Investigator
  
  杉山俊博
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Akita University
肝・胆・膵系幹細胞の発生・分化・再生の分子機構Principal Investigator
- Principal Investigator
  
  杉山俊博
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
Establishment of isolation procedure of human hepatic stem cell and tissue engineering technique to reconstitute hepatic tissue using the stem cell.Principal Investigator
- Principal Investigator
  
  SUGIYAMA Toshihiro
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Akita Univereity
Development of the artificial organs from human stem cells.Principal Investigator
- Principal Investigator
  
  SUGIYAMA Toshihiro
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for University and Society Collaboration
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Akita University
肝細胞分化能をもつoval cellにおける転写制御因子の発現と機能Principal Investigator
- Principal Investigator
  
  杉山俊博
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Akita University
Analysis of functional domains of Wilson's disease protein (ATP7B).
- Principal Investigator
  
  TERADA Kunihiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  AKITA UNIVERSITY
LECラットにおける肝臓始原細胞株の樹立と肝細胞への分化機構Principal Investigator
- Principal Investigator
  
  杉山俊博
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Akita University
The expression and regulation of the liver enriched transcription factors involving in liver differentiationPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Toshihiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Akita University
ラット肝発癌過程に出現するoval cellの肝細胞への分化能Principal Investigator
- Principal Investigator
  
  杉山俊博
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Akita University
肝癌自然発症過程に出現する肝臓始原細胞の多分化能Principal Investigator
- Principal Investigator
  
  杉山俊博
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Akita University
An antibody against single-stranded DNA useful for detecting apoptotic cells : production and applications for development, differentiation and carcinogenesisPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Toshihiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Akita University
Functional expression of Wilson's disease gene in the LEC rats by adenovirus-mediated gene delivery.
- Principal Investigator
  
  TERADA Kunihiko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Akita University
銅代謝異常を伴うLECラット肝発がんの分子機構の解明
- Principal Investigator
  
  森道夫
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
肝癌自然発症ラット(LECラット)におけるS-アデノシルメチオニンの腫瘍抑制効果Principal Investigator
- Principal Investigator
  
  杉山俊博
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Akita University
ウイルソン病モデルラット(LECラット)に見られる銅トランスポーターの機能異常Principal Investigator
- Principal Investigator
  
  杉山俊博
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Akita University
銅代謝異常を伴うLECラット肝発癌の分子機構の解明
- Principal Investigator
  
  吉田廸弘
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
LECラットにおける肝炎・肝癌発症に関与する銅代謝酵素の検索Principal Investigator
- Principal Investigator
  
  杉山俊博
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Akita University
銅代謝異常を伴うLECラット肝癌発生の分子機構の解明
- Principal Investigator
  
  武市紀年
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
肝炎・肝癌自然発症LECラットを用いた肝癌の発生と進展に関する分子病理学的研究
- Principal Investigator
  
  武市紀年
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
肝炎・肝癌自然発症LECラットを用いた肝癌の発生と進展に関する分子病理学的研究
- Principal Investigator
  
  武市紀年
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
Correlation between the spontaneous hepatitis and hepatoma and the disorder of methyl group metabolism in LEC ratsPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Toshihiro
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Akita University
  Osaka University
癌化におけるス-パ-オキサイドの役割
- Principal Investigator
  
  谷口直之
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
癌化におけるスーパーオキサイドの役割
- Principal Investigator
  
  TANIGUCHI Naoyuki
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
Abnormal Expression of Cytochrome P-450 in LEC Rats with Metabolic Predisposition to Spontaneous HepatitisPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Toshihiro
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
癌化におけるスーパーオキサイドの役割
- Principal Investigator
  
  谷口直之
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
Inactivation of Cu,Zn-superoxide dismutase due to glycation
- Principal Investigator
  
  TANIGUCHI Naoyuki
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  代謝生物化学
- Research Institution
  Osaka University Medical School
癌化におけるスーパーオキサイドディスムターゼの不活性化の意義
- Principal Investigator
  
  谷口直之
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
Hepatic drug metabolizing enzymes in the spontaneous hepatitis and hepatoma of an animal model LEC ratPrincipal Investigator
- Principal Investigator
  
  TOSHIHIRO SUGIYAMA
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University Medical School
Relationship between debromination reaction of halogen compounds and organ toxicityPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Toshihiro, 山野俊雄
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University

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All Journal Article Presentation Patent

[Journal Article] Relationship between Restoring Vitality and Electrical Potential of Microbubble2015
- Author(s)
  Shun Sakai, Hiroaki Hasegawa, Yutaka Masuda and Toshihiro Sugiyama
- Journal Title
  
  ASME-JSME-KSME Joint Fluids Engineering Conference 2015
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25350834
[Journal Article] Application of spontaneously immortalized odontoblast cells in tooth regeneration2009
- Author(s)
  Arany S, Kawagoe M. and Sugiyama T.
- Journal Title
  
  Biochem. Biophys. Res. Communn 381
  
  Pages: 84-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Expression and localization of regenerating gene I in a rat liver regeneration model2009
- Author(s)
  Wang JS, Koyota S, Zhou XP, Ueno Y, Ma L, Kawagoe M, Koizumi Y, Hiroshi Okamoto H, Sugiyama T.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 380
  
  Pages: 472-477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Nerve growth factor promotes differentiation of odontoblast-like cells2009
- Author(s)
  Arany S, Koyota S, Sugiyama T.
- Journal Title
  
  J Cell Biochem 106
  
  Pages: 539-545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Simaomicin α, a polycyclic xanthone, induces G1 arrest with suppression of pRb phosphorylation2009
- Author(s)
  Koizumi Y, Tomoda H, Kumagai A, Zhou XP, Koyota S, Sugiyama T
- Journal Title
  
  Cancer Sci 100
  
  Pages: 322-326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Niemann-Pick C1 protein transports copper to the secretory compartment from late endosomes where ATP7B resides2008
- Author(s)
  Harada M, Kumemura H, Koga H, Kawaguchi T,Terada K, Hanada S, Taniguchi E, Koizumi Y, Koyota S, Ninomiya H, Ueno K, Sugiyama T, Sata M.
- Journal Title
  
  Exp. Cell Res 315
  
  Pages: 119-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Review of apoptotic and non-apoptotic events in non-ciliated cells of the mammalian oviduct2008
- Author(s)
  Steffl M., Schweiger M., Sugiyama T., Amselgruber W.M.
- Journal Title
  
  Ann. Anat 190
  
  Pages: 46-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Proteomic analysis identifies proteins that continue to grow hepatic stem-like cells without differentiation2008
- Author(s)
  Saheki T., Ito H., Sekiguchi A., Nishina A., Sugiyama T., Izumi T., Kojima I.
- Journal Title
  
  Cytotech. 57
  
  Pages: 137-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Simaomicin α, a polycyclic xanthone, induces G1 arrest with suppression of pRb phosphorylation2008
- Author(s)
  Koizumi Y, Tomoda H, Kumagai A, Zhou XP, Koyota S, Sugiyama T
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 322-326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] I. REG I α is a reliable marker of chemoradiosensitivity in squamous cell esophageal cancer patients2008
- Author(s)
  Hayashi K, Motoyama S, Sugiyama T, Izumi JI, Anbai A, Nanjo H, Watanabe H, Maruyama K, Minamiya Y, Koyota S, Koizumi Y, Takasawa S, Murata K, Ogawa J
- Journal Title
  
  Ann. Surg. Oncol. 15
  
  Pages: 1224-1231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Differentiation of an ameloblast-lineage cell line (ALC) is induced by Sonic hedgehog signaling2007
- Author(s)
  Takahashi S., Kawashima N., Sakamoto K, Nakata A., Kameda T., Sugiyama T., Katsube K., Suda H.
- Journal Title
  
  Biochem.Biophys. Res. Comm 353
  
  Pages: 405-411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Gadolinium chloride suppresses styrene-induced cytochrome P450s expression in rat liver2007
- Author(s)
  Hirasawa F, Kawagoe M, Wang JS, Arany S, Zhou XP, Kumagai A, Koizumi Y, Koyota S, Sugiyama T.
- Journal Title
  
  Biomed. Res 28
  
  Pages: 323-330
- NAID
  130004470694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Synergistic effect on reactive oxygen scavenging activity of fermented okara and banana by XYZ system2007
- Author(s)
  Suruga K, Akiyama Y, Kadokura K, Sekino Y, Kawagoe M, Komatsu Y, Sugiyama T
- Journal Title
  
  Food Sci. Technol. Res 13
  
  Pages: 139-144
- NAID
  10019577801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Comparison of aspartic acid racemization between mammoth and human dentinal tissues2007
- Author(s)
  Arany S, Ohtani S, Yamamoto T, Sugiyama T.
- Journal Title
  
  Arch. Oral Biol 52
  
  Pages: 20-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] REG I expression predicts long-term survival among locally advanced thoracic suamous cell eophageal cancer patients treated with neoadjuvant chemoradiotherapy followed by esophagectomy2006
- Author(s)
  Motoyama S, Sugiyama T, Ueno Y, Okamoto H, Takasawa S, Nanjo H, Watanabe H, Maruyama K, Okuyama M, Ogawa J.
- Journal Title
  
  Ann. Surg. Oncol 13
  
  Pages: 1724-1731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Phenotype properties of a novel spontaneously immortalized odontoblast-lineage cell line2006
- Author(s)
  Arany S., Nakata A., Kameda T., Koyota S., Ueno Y., Sugiyama T.
- Journal Title
  
  Biochem. Biophys. Res. Commun 342
  
  Pages: 718-724
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Paenidase, A novel D-aspartyl endopeptidase from Paenibacillus sp. B38 : Purification and substrate specificity2006
- Author(s)
  Takahashi S., Ogasawara H., Hiwatashi K., Hori K., Hata K., Tachibana T., Itoh Y., Sugiyama T.
- Journal Title
  
  J. Biochem.(Tokyo) 139
  
  Pages: 197-202
- NAID
  10018847533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Effects of nucleotides on the interaction of renin with GlcNAc 2-epimrase (renin binding protein, RnBP)2006
- Author(s)
  Takahashi S, Hori K, Ogasawara H, Hiwatashi K, Sugiyama T.
- Journal Title
  
  J. Biochem.(Tokyo) 140
  
  Pages: 725-730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300159
[Journal Article] Roles of forkhead transcription factor Foxc2 (MFH-1) and endothelin receptor A in cardiovascular morphogenesis.2005
- Author(s)
  Kanzaki-Kato N., Tamakoshi T., Fu Y., Chandra A., Itakura T., Uezato T., Tanaka T., Clouthier D.E., Sugiyama T., Yanagisawa M., Miura N.
- Journal Title
  
  Cardiovasc.Res. 65
  
  Pages: 711-718
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Orally administrated rare earth element cerium induces metallothionein synthesis and increases glutathione in the mouse liver.2005
- Author(s)
  Kawagoe M., Hirasawa F., Wang S.-C., Liu Y., Ueno Y., Sugiyama T.
- Journal Title
  
  Life Sci. 77
  
  Pages: 922-937
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Application of genetically modified feeder cells for culture of keratinocytes.2005
- Author(s)
  Kameda T., Sugiyama T.
- Journal Title
  
  Methods Mol.Biol. 289
  
  Pages: 29-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Protection of hepatocytes from apoptosis by a novel substance from actinomycetes culture medium.2005
- Author(s)
  Liu Y., Takahashi S., Ogasawara H., Seo H.G., Kawagoe M., Hirasawa F., Guo N., Ueno Y., Kameda T., Sugiyama T.
- Journal Title
  
  Biomed.Res. 26
  
  Pages: 9-14
- NAID
  130004903688
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Oncostatin M inhibits proliferation of rat oval cells, OC15-5, inducing differentiation into hepatocytes.2005
- Author(s)
  Okaya A., Kitanaka J., Kitanaka N., Satake M., Kim Y., Terada K., Sugiyama T., Takemura M., Fujimoto J., Terada N., Miyajima A., Tsujimura T.
- Journal Title
  
  Am.J.Pathol. 166
  
  Pages: 709-719
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Transplantation of rat hepatic stem-like (HSL) cells with collagen matrices.2005
- Author(s)
  Ueno Y., Nagai H., Watanabe G., Ishikawa K., Yoshikawa K., Koizumi Y., Kameda T., Sugiyama T.
- Journal Title
  
  Hepatol.Res. 33
  
  Pages: 277-284
- NAID
  10016809917
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Styrene monomer primarily induces CYP2B1 mRNA in the rat liver.2005
- Author(s)
  Hirasawa F., Kawagoe M., Arany S., Koizumi Y., Ueno Y., Sugiyama T.
- Journal Title
  
  Xenobiotica 35
  
  Pages: 1089-1099
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Repeated immunization induces the increase in fucose content on antigen-specific IgG N-linked oligosaccharides.2005
- Author(s)
  Guo N., Liu Y., Masuda Y., Kawagoe M., Uen, Y., Kameda T., Sugiyama T.
- Journal Title
  
  Clin.Biochem. 38
  
  Pages: 149-153
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Differentiation of adult hepatic stem-like cells into pancreatic endocrine cells.2005
- Author(s)
  Yamada S., Terada K., Ueno Y., Sugiyama T., Seno M., Kojima I.
- Journal Title
  
  Cell Transplant. 14
  
  Pages: 647-653
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Amino acid residues conferring the nucleotide binding properties of N-acetyl-D-gurucosamine 2-epimerase (renin binding protein).2005
- Author(s)
  Takahashi S., Ogasawara H., Hiwatashi K., Hata K., Hori K., Koizumi Y., Sugiyama T.
- Journal Title
  
  Biomed.Res. 26
  
  Pages: 117-121
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] The Wilson disease protein ATP7B resides in the late endosomes with Rab7 and the Niemann-Pick C1 Protein.2005
- Author(s)
  Harada M., Kawaguchi T., Kumemura H., Terada K., Ninomiya H., Taniguchi E., Hanada S., Baba S., Maeyama M., Koga H., Ueno T., Furuta K., Suganuma T., Sugiyama T., Sata M.
- Journal Title
  
  Am.J.Pathol. 166
  
  Pages: 499-510
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Application of genetically modified feeder cells for culture of keratinocytes.2004
- Author(s)
  Kameda T., Sugiyama T.
- Journal Title
  
  Epidermal Cells-Methods and Protocols (Turksen, K., ed.) (Human Press, Totowa, New Jersey)
  
  Pages: 29-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Peroxisome proliferator-activated receptor gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2, and ciglitazone, induce growth inhibition and cell cycle arrest in hepatic oval cells.2004
- Author(s)
  Cheng J., Nakamura H., Imanishi H., Liu W., Morisaki T., Sugiyama T., Hada T.
- Journal Title
  
  Biochem.Biophy.Res.Commun. 322
  
  Pages: 458-464
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Purification and characterization of a novel prolyl aminopeptidase from Maitake (Grifolafrondosa).2004
- Author(s)
  Hiwatashi K., Hori K, Takahashi K., Kagaya A., Inoue S., Sugiyama T., Takahashi S.
- Journal Title
  
  Biosci.Biotechnol.Biochem. 68
  
  Pages: 1395-1397
- NAID
  10013287045
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Potential role of p53 mutation in chemical hepatocarcinogenesis of rats.2004
- Author(s)
  Deng W.G., Fu Y., Li Y.L., Sugiyama T.
- Journal Title
  
  World J.Gastroenterol. 10
  
  Pages: 46-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Enhanced proliferation of hepatic progenitor cells in rats after portal branch occlusion.2004
- Author(s)
  Ise N., Sato T., Yasui O., Watanabe G., Koyama K., Terada K., Sugiyama T., Yamamoto Y.
- Journal Title
  
  Liver Transpl. 10
  
  Pages: 748-754
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Application of collagen scaffolds for hepatic stem-like cell transplantation.2004
- Author(s)
  Ueno Y., Terada K., Nagai H., Watanabe G., Ishikawa K., Yoshikawa K., Hirayama Y., Endo E., Kameda T., Liu Y., Sugiyama T.
- Journal Title
  
  Akita J.Med. 31
  
  Pages: 113-119
- NAID
  110001046058
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] A hypothermic-temperature-sensitive gene silencing by the mammalian RNAi.2004
- Author(s)
  Kameda T., Ikegami K., Liu Y., Terada K., Sugiyama T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 315
  
  Pages: 599-602
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Prognostic value of the Cu-transporting ATPase in ovarian carcinoma patients receiving cisplatin-based chemotherapy.2004
- Author(s)
  Nakayama K., Kanzaki A., Terada K., Mutoh M., Ogawa K., Sugiyama T., Takenoshita S., Itoh K., Yaegashi N., Miyazaki K., Neamati N., Takebayashi Y.
- Journal Title
  
  Clin.Cancer Res. 10
  
  Pages: 2804-2811
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) in human hepatocellular carcinoma.2004
- Author(s)
  Sugeno H., Takebayashi Y., Higashimoto M., Ogura Y., Shibukawa G., Kanzaki A., Terada K., Sugiyama T., Watanabe K., Katoh R., Nitta Y., Fukushima T., Koyama Y., Inoue N., Sekikawa K., Ogawa K., Sato Y., Takenoshita S.
- Journal Title
  
  Anticancer Res. 24
  
  Pages: 1045-1048
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Restoration of copper metabolism and rescue of hepatic abnormalities in LEC rats, an animal model of Wilson's disease, by expression of human ATP7B gene.2004
- Author(s)
  Yan M.Y., Miyoshi I., Hirabayashi M., Su M., Mototani Y., Okamura T., Terada K., Ueda M., Enomoto K., Sugiyama T., Kasai N.
- Journal Title
  
  Biochim.Biophys.Acta 1690
  
  Pages: 208-219
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] A glycoside of Nicotina tabacum affects mouse dopaminergic behavior.2003
- Author(s)
  Masuda Y., Ohnuma S., Kawagoe M., Sugiyama T.
- Journal Title
  
  Exp.Clin.Pharmacol. 25
  
  Pages: 41-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Production of monoclonal antibodies recognizing human hair follicle keratinocytes.2003
- Author(s)
  Hatakeyama S., Ma Y.-Z., Miura N., Abe S., Kameda T., Sakamoto K., Sugiyama T.
- Journal Title
  
  Hybrid Hybridomics 22
  
  Pages: 127-130
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Wilson disease protein ATP7B is localized in the late endosomes in a polarized human hepatocyte cell line. Int.2003
- Author(s)
  Harada M., Kumemura H., Sakisaka S., Shishido S., Taniguchi E., Kawaguchi T., Hanada S., Koga H., Kumashiro R., Ueno T., Suganuma T., Furuta K., Namba M., Sugiyama T., Sata M.
- Journal Title
  
  Int.J.Mol.Med. 11
  
  Pages: 293-298
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.2003
- Author(s)
  Wang T., Tamakoshi T., Uezato T., Shu F., Kanzaki-Kato N., Fu Y., Koseki H., Yoshida N., Sugiyama T., Miura N.
- Journal Title
  
  Dev.Biol. 259
  
  Pages: 83-94
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Copper-transporting P-type adenosine triphosphatase (ATP7B) is expressed in human gastric carcinoma.2003
- Author(s)
  Ohbu M., Ogawa K., Konno S., Kanzaki A., Terada K., Sugiyama T., Takebayashi Y.
- Journal Title
  
  Cancer Lett. 189
  
  Pages: 33-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Analysis of the cellular heterogeneity in the basal layer of mouse ear epidermis : an approach from partial decomposition in vitro and retroviral cell marking in vivo.2003
- Author(s)
  Kameda T., Nakata A., Mizutani T., Terada K., Iba H., Sugiyama T.
- Journal Title
  
  Exp. Cell Res. 283
  
  Pages: 167-183
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Expression of copper-transporting P-type adenosine triphosphatase in human esophageal carcinoma.2003
- Author(s)
  Higashimoto M., Kanzaki A., Shimakawa T., Konno S., Naritaka Y., Nitta Y., Mori S., Shirata S., Yoshida A., Terada K., Sugiyama T., Ogawa K., Takebayashi Y.
- Journal Title
  
  Int.J.Mol.Med. 11
  
  Pages: 337-341
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Salivary gland progenitor cells induced by duct ligation differentiate into hepatic and pancreatic lineages.2003
- Author(s)
  Okumura K., Nakamura K., Hisatomi Y., Nagano K., Tanaka Y., Terada K., Sugiyama T., Umeyama K., Matsumoto K., Yamamoto T., Endo F.
- Journal Title
  
  Hepatology 38
  
  Pages: 104-113
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] The role of IgG carbohydrates in anaphylaxis : a possible way for antigen-specific anaphylaxis treatment by deglycosylated IgG.2003
- Author(s)
  Guo N., Liu Y., Masuda Y., Kawarada Y., Kawagoe M., Yoshikawa K., Kameda T., Sugiyama T.
- Journal Title
  
  Biomed.Res. 24
  
  Pages: 291-297
- NAID
  130004705173
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Establishment and characterization of a spontaneously immortalized mouse ameloblast-lineage cell line.2003
- Author(s)
  Nakata A., Kameda T., Nagai H., Ikegami K., Duan Y., Terada K., Sugiyama T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 308
  
  Pages: 834-839
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) as a chemoresistance marker in human oral squamous cell carcinoma treated with cisplatin.2003
- Author(s)
  Miyashita H., Nitta Y., Mori S., Kanzaki A., Nakayama K., Terada K., Sugiyama T., Kawamura H., Sato A., Morikawa H., Motegi K., Takebayashi Y.
- Journal Title
  
  Oral Oncol. 39
  
  Pages: 157-162
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Mutation and expression of the p53 gene during chemical hepatocarcinogenesis in F344 rats.2003
- Author(s)
  Fu Y., Deng W., Kawarada Y., Kawagoe M., Ma Y.-Z., Li X., Guo N., Kameda T., Terada K., Sugiyama T.
- Journal Title
  
  Biochim.Biophys.Acta 1628
  
  Pages: 40-49
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Pharmacological mechanism in slip-down behavior of mice.2003
- Author(s)
  Masuda Y., Suzuki M., Takemura T., Sugawara J., Guo N., Liu Y., Kawarada Y., Shimizu T., Sugiyama T.
- Journal Title
  
  Tohoku J.Exp.Med. 201
  
  Pages: 23-27
- NAID
  10011990937
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Journal Article] Epimorphin is involved in differentiation of rat hepatic stem-like cells through cell-cell contact.2003
- Author(s)
  Miura K., Nagai H., Ueno Y., Goto T., Mikami K., Nakane K., Yoneyama K., Watanabe D., Terada K., Sugiyama 'T., Imai K., Senoo H., Watanabe S.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 311
  
  Pages: 415-423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Patent] 海洋ミネラル成分からなる動脈硬化治療及び/または予防剤2008
- Inventor(s)
  杉山俊博, 川越政美
- Industrial Property Rights Holder
  国立大学法人秋田大学, 小椋武
- Industrial Property Number
  2008-214092
- Filing Date
  2008-08-04
- Data Source
  KAKENHI-PROJECT-18300159
[Patent] 象牙芽前駆細胞を用いた歯組織再生方法2006
- Inventor(s)
  杉山俊博、アラニー・シルビア
- Industrial Property Rights Holder
  秋田大学
- Patent Publication Number
  2007-209244
- Filing Date
  2006-02-09
- Data Source
  KAKENHI-PROJECT-18300159
[Patent] 象牙芽前駆細胞を用いた歯組織再生方法2006
- Inventor(s)
  杉山俊博, アラニー・シルビア
- Industrial Property Rights Holder
  秋田大学
- Filing Date
  2006-02-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Patent] 抗血液凝固作用を有する希少元素セリウム及びその誘導体2005
- Inventor(s)
  杉山俊博, 川越政美
- Industrial Property Rights Holder
  秋田大学
- Filing Date
  2005-04-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Patent] 抗血液凝固作用を有する希少元素セリウム及びその誘導体2005
- Inventor(s)
  杉山俊博, 川越政美
- Industrial Property Rights Holder
  秋田大学
- Filing Date
  2005-04-20
- Data Source
  KAKENHI-PROJECT-15300154
[Patent] 培養温度による哺乳類細胞でのRNAi効果の制御技術2004
- Inventor(s)
  杉山俊博, 亀田隆
- Industrial Property Rights Holder
  杉山俊博
- Filing Date
  2004-03-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Patent] アメロブラスト前駆細胞を用いた歯周組織再生技術2004
- Inventor(s)
  杉山俊博, 亀田隆, 中田憲
- Industrial Property Rights Holder
  杉山俊博, (株)エーティーラボ
- Filing Date
  2004-02-09
- Data Source
  KAKENHI-PROJECT-15300154
[Patent] アメロブラスト前駆細胞を用いた歯周組織再生技術2003
- Inventor(s)
  杉山俊博, 亀田隆, 中田憲
- Industrial Property Rights Holder
  株式会社エーティーラボ, 杉山俊博
- Filing Date
  2003-09-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300154
[Presentation] Behavior of Microbubbles with High Electrical Potential and Its Application to Vitality2016
- Author(s)
  Sakai, S., Hasegawa, H., Masuda, Y. and Sugiyama, T.
- Organizer
  The First Pacific Rim Thermal Engineering Conference
- Place of Presentation
  Waikoloa Beach Marriott Resort & Spa, Hawaii, USA
- Year and Date
  2016-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25350834
[Presentation] ゼータ電位の異なるマイクロバブル浴による気力回復2015
- Author(s)
  酒井駿、長谷川裕晃、増田豊、杉山俊博
- Organizer
  日本混相流学会混相流シンポジウム2015
- Place of Presentation
  高知工科大学
- Year and Date
  2015-08-04
- Data Source
  KAKENHI-PROJECT-25350834
[Presentation] マイクロバブルの電気的特性と気力回復効果2015
- Author(s)
  酒井駿、長谷川裕晃、増田豊、杉山俊博
- Organizer
  日本機械学会東北支部第50期総会・講演会
- Place of Presentation
  東北大学工学研究科
- Year and Date
  2015-03-13
- Data Source
  KAKENHI-PROJECT-25350834
[Presentation] ゼータ電位の異なる微細気泡の挙動とその生理的効果2015
- Author(s)
  酒井駿、長谷川裕晃、増田豊、杉山俊博
- Organizer
  日本機械学会流体工学部門講演会
- Place of Presentation
  東京理科大学
- Year and Date
  2015-11-07
- Data Source
  KAKENHI-PROJECT-25350834
[Presentation] マイクロバブル炭酸泉による気力増加2014
- Author(s)
  酒井駿、長谷川裕晃、増田豊、杉山俊博
- Organizer
  日本マイクロ・ナノバブル学会学術総会（第3回）
- Place of Presentation
  明治大学駿河台キャンパス
- Year and Date
  2014-12-07
- Data Source
  KAKENHI-PROJECT-25350834
[Presentation] マウスエナメル芽細胞前駆細胞と象牙芽細胞前駆細胞の共培養による石灰化促進2010
- Author(s)
  小代田宗一, 小代田理江, 堀川彩夏, 牧野晃大, 遊佐和之, 小泉幸央, 杉山俊博
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21592528
[Presentation] 象牙芽前駆細胞を用いた歯再生2009
- Author(s)
  杉山俊博, Szilvia Arany, 川越政美, 馬莉, 小代田宗一
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18300159
[Presentation] Study of butyrate signal transduction pathways in rat hepatic stem-like cells. Animal Cell Technology in Bioscience2008
- Author(s)
  Saheki T, Mukai Y, Saito K, Tajima E,Katakura K, Nishina A, Kishi M, Izumi T, Sugiyama T, Kojima I.
- Organizer
  Bioengineering and Bioindustries
- Place of Presentation
  November, Fukuoka
- Data Source
  KAKENHI-PROJECT-18300159
[Presentation] ラット肝再生モデルにおけるReg I の発現と局在2008
- Author(s)
  王静舒, 馬莉, 小代田宗一, 杉山俊博
- Organizer
  BMB2008第31回日本分子生物学会・第81回日本生化学会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18300159
[Presentation] ラット肝臓幹様(HSL)細胞を酪酸処理したときのProhibitinの応答2007
- Author(s)
  佐伯俊彦, 和泉孝志, 杉山俊博, 小島至
- Organizer
  BMB2007第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18300159
[Presentation] マイクロバブル浴による気力回復
- Author(s)
  酒井駿、長谷川裕晃、増田豊、杉山俊博
- Organizer
  日本混相流学会混相流シンポジウム2014
- Place of Presentation
  道民センター「かでる2・7」(札幌市)
- Year and Date
  2014-07-28 – 2014-07-30
- Data Source
  KAKENHI-PROJECT-25350834

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SUGIYAMA Toshihiro 杉山 俊博

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Development of the cell transplantation therapy for the tooth regeneration using the committed progenitor cell of the tooth established from the tooth germPrincipal Investigator

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Search for facto s that induce transdifferentiation from liver stem cell to epitheial cells of digestive gland and development with tissue engineeringPrincipal Investigator

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肝・胆・膵系ステムセル・バイオロジーと臓器再生医療への展開Principal Investigator

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肝特異的転写因子による肝臓幹様細胞(oval cell)の増殖・分化の制御機構Principal Investigator

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肝・胆・膵系幹細胞の発生・分化・再生の分子機構Principal Investigator

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Establishment of isolation procedure of human hepatic stem cell and tissue engineering technique to reconstitute hepatic tissue using the stem cell.Principal Investigator

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Development of the artificial organs from human stem cells.Principal Investigator

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SUGIYAMA Toshihiro 杉山俊博