Kojima Itaru 小島至

… Alternative Names

KOJIMA Itaru 小島至

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Researcher Number	60143492
Other IDs
Affiliation (Current)	2025: 群馬大学, 生体調節研究所, 名誉教授
Affiliation (based on the past Project Information) *help	2016 – 2018: 群馬大学, 生体調節研究所, 名誉教授 1994 – 2015: Department of Cell Biology, Institute for Molecular and Cellular Regulations, Gu, 生体調節研究所, 教授 2002: 群馬大学, 医学部, 教授 1999: 群馬大学, 生体調整研究所, 教授 1999: 群馬大学, 生体調節研研究所, 教授 … More 1990 – 1994: Professor, Institute of Endocrinology, Gunma University, 内分泌研究所, 教授 1991 – 1993: 群馬大学, 内分泌研究所・薬学部門, 教授 1992: Professor, Inst. of Endocrinology Gunma University, 内分泌研究所教授 1990: 群馬大学, 医学部, 教授 1989: 東京大学, 保健センター, 講師 1988: 東京厚生年金病院, 内科, 医長 1988: 東京大学, 医学部第四内科, 助手 1986 – 1987: 東京大学, 医学部(分), 助手 Less
Review Section/Research Field	Principal Investigator 内分泌・代謝学 / Metabolomics / Metabolomics / Endocrinology / Kidney internal medicine / Gastroenterology / Respiratory organ internal medicine / Biological Sciences Except Principal Investigator Digestive surgery / 内分泌・代謝学 … More / Digestive surgery / Medical pharmacy / Biological pharmacy / Endocrinology / General surgery / Kidney internal medicine / Biological pharmacy / Metabolomics / Ophthalmology / Anesthesiology/Resuscitation studies / Pathological medical chemistry / Circulatory organs internal medicine / 応用薬理学・医療系薬学 Less
Keywords	Principal Investigator カルシウム / 細胞増殖 / 増殖因子 / インスリン / 膵β細胞 / カルシウム透過性チャネル / 分化誘導 / イオンチャネル / アクチビン / insulin … More / 幹細胞 / フォリスタチン / アクチビンA / differentiation / activin A / β細胞 / 糖尿病 / 膵内分泌細胞 / 甘味受容体 / 再生医学 / 分化誘導因子 / インスリン様成長因子 / 脂肪細胞 / 血管平滑筋細胞 / activin / diabetes / stem cell / ベータセルリン / follistatin / growth factor / サイクリックAMP / TGF-β / 分化 / G蛋白 / オートクリン因子 / regeneration medicine / regeneration / pancreatic β cells / betacellulin / 肝細胞増殖因子 / 肝再生 / pancreatic endocrine cell / オートクリン機構 / autocrine / growth / TGF-beta / アポトーシス / Cキナーゼ / 肺線維症 / 再生医療 / 管腔形成 / 再生 / 尿細管 / 動脈硬化 / 細胞周期 / パッチクランプ / GTP結合蛋白 / Cell-cycle / Diacylglycerol / Calcium / Growth / Insulin-like Growth Factor / ジアシルグリセロール / ジアシルグリセロ-ル / fibrosis / 血管内皮 / 血管新生 / 肝硬変 / cell therapy / cell transplantation / regenerative medicine / 細胞療法 / 細胞移植 / epithelial cell / apoptosis / renal tubular cell / 腎尿細管 / 上皮細胞 / diabetes mellitus / pancreatic stem cell / 膵幹細胞 / HGF / transcription factor / 遺伝子発現 / 転写因子 / islet / 遺伝子 / ランゲルハンス島 / hepatocyte growth factor / beta-cell / 膵B細胞 / DNA synthesis / hepatic necrosis / hepatectomy / liver regeneration / 肝壊死 / DNA合成 / 肝細胞壊死 / 肝切除 / paracrine / calcium / 局所因子 / パラクリン機構 / パラクリン因子 / inhibin / 下垂体ホルモン / 肝細胞 / 活性因子 / インヒビン / 糖代謝 / グルコース感知受容体 / グルコース / インスリン分泌 / GLP1 / 小腸内分泌細胞 / GLP-1 / 分泌 / TRPV2 / コラーゲン / 筋繊維芽細胞 / マクロファージ / 肺繊維症 / 線維化 / 間葉系幹細胞 / 骨髄細胞 / 膵再生 / 形態形成 / 発生 / 糸球体 / チャネル / RB蛋白 / サイクリン / 血管平滑筋 / 機械受容チャネル / 器械受容チャネル / グリコーストランスポーター / グルコーストランスポーター / 増殖抑制 … More Except Principal Investigator 肝移植 / アクチビン / DIF / 肝再生 / フォリスタチン / 糖尿病 / 細胞性粘菌 / activin A / PDE1 / Dictyostelium / DIF-1 / TGF-β / liver regeneration / follistatin / カルシウム / がん / 分化誘導因子 / 抗腫瘍因子 / adenovirus vector / インスリン / G蛋白 / GTP結合蛋白 / 成長因子 / 有茎分節腸管 / 肝組織移植 / 肝不全 / 人工肝臓 / 癌 / K562 / Erk / calcium / cAMP / artificial liver / activin / SNARE / Rab4 / gene transfer / 遺伝子導入 / ペプチド合成 / hepatectomy / 90%肝切除 / glucose transporter / insulin / グルコーストランスポーター / neuropeptide / hormone / ペプチド / 神経ペプチド / ホルモン / カルシウムチャネル / 肝組織片移植 / 肝細胞移植 / 補助肝臓 / トリパノソーマ / 免疫 / 肝オルガノイド / 遺伝子治療 / 幹細胞 / 肝・胆・膵 / 生理活性ペプチド / 甘味受容体 / NADPH / パルミチル化 / インスリン分泌 / インクレチン / ブドウ糖 / 体内型補助肝･膵臓 / 膵移植 / 体内型補助肝・膵臓 / 膵島細胞移植 / 膵組織片移植 / Zinc / anti-tumor agent / 亜鉛 / macrophage / TRP channels / 増殖因子 / TRPVファミリー / トランスロケーション / TRPV / マクロファージ / TRPチャネル / renal fibrosis / renal regeneration / 筋繊維芽細胞 / 繊維芽細胞 / 腎繊維化 / 筋線維芽細胞 / 形質転換 / 線維芽細胞 / 腎線維化 / 腎臓の再生 / Cancer / Anti-tumor drug / regenerative medicine / liver organoid / epithelial stem like cell / adult stem cells / 肝上皮様細胞 / 再生医学 / 肝上皮性細胞 / 体性幹細胞 / apotosis / leukemia cells / anti-tumor factor / calcineurin / differentiation inducing factor / cellular slime mold / protein kinaseB / Statシグナル伝達 / Jac / Jarkat細胞 / 卵母細胞 / Xenopus laevis / 抗腫瘍作用 / 抗ウイルス作用 / カスパーゼ / Insulinoma細胞 / インシュリン / アポトーシス / 白血病細胞 / カルシニューリン / dominant negative receptor of TGF-β and activin A / hepatocyte transplantation / liver stem-like cell / 肝細胞培養 / 人工肝 / TGF-β and activin receptors / 肝幹細胞 / syntaxin4 / GTP-binding protein / ダイナミン / シンタキシン / dominant negative receptor of activin A / TGF-β受容体 / virus vector / activin変異受容体 / analog of follistatin / activin A, / 肝切除 / mastoparan / G-protein / グルコーストランスポート / マストパラン / グリコーストランスポーター / glucokinase / NOD-mice / TGF-beta / diabetes mellitus / B-cells of pancreatic islets / gene therapy / リンパ球 / T細胞 / 自己抗原 / 自己免疫疾患 / サイトカイン / I型糖尿病 / 膵ラ島B細胞 / galanin / pancreatatin / neuropeptide Y / agonist / antagonist / peptide / ガラニン / パンクレアスタチン / ニューロペプチドY / アゴニスト / アンタゴニスト / peptide structure / peptide isolation / differentiation-inducing factor / growth factor / biologically active peptide / 生理活性 / 構造決定 / 抽出精製 / IGF-I受容体 / 脱共役 / EGF / PDGF / IGF-II受容体 / DNA合成 / 細胞周期依存性 / GTP結合トランスデューサー / IGF受容体 / influx / Calcium / IGF / 副甲状腺ホルモン様蛋白 / イオンチャンネル / カルシウムイオン / HHM因子 / ホルモン不応症 / 遺伝子発現 / 情報伝達系 / 細胞内【Ca^(2+)】濃度 / 【Ca^(2+)】流入 / ホルモンの作用機序 / 肝幹様細胞共充填 / 肝組織片充填 / 体内型補助人工肝臓 / 肝組織幹様細胞共充填 / 肝幹様細胞 / 有茎腸管グラフト / 体内型補助肝臓 / 肝幹様細胞の分化誘導 / 肝幹様細胞移植 / 走化性運動 / ミトコンドリア / 有茎腸管内肝組織片移植 / 人工補助肝臓 / 有茎腸管内移植 / 有茎腸管内肝組織移植 / 糖尿病網膜症 / 血管新生 / 低分子化合物 / 糖代謝 / 抗腫瘍剤 / 肥満 / angiogenesis / Smad / VEGF / FGF2 / 大量培養 / 肝上皮性幹様細胞 / 発生・分化 / 膵β細胞 / 再生医療 / ステムセル・バイオロジー / 遺伝子発現転写調節 / 動脈硬化 / 平滑筋 / 内皮 / 血管 / 消化腺上皮 / 発生・分化・再生 / 膵臓 / 胆管 / 肝臓 / アミド化反応 / アミド化カルシトニン / グリシン付加カルシトニン / 細胞医薬 / 限定切断 / カルシトニン Less

Elucidation of three new molecular bases in the mechanisms of insulin secretion
- Principal Investigator
  
  Komatsu Mitsuhisa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Shinshu University
Development of auxiliary liver and pancreas using a small intestinal segment packed together with liver micro fragments and pancreatic islets.
- Principal Investigator
  
  Kogure Kimitaka
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University
Idenitification of the endogenous ligand for the sweet taste receptor expressed in pancreatic beta-cellsPrincipal Investigator
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
Development of an auxiliary liver using a small intestinal segment packed together with liver micro fragments and stem-like cells of the liver
- Principal Investigator
  
  Kogure Kimitaka
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University
Study on the bio-active molecule, DIF, found in the cellular slime mold Dictyostelium discoideum
- Principal Investigator
  
  Kubohara Yuzuru
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Juntendo University
  Gunma University
Regulation of the endocrine system by the sweet taste receptorPrincipal Investigator
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  Gunma University
Sweet Tase Receptor Expressed in Pancreatic β-cells: PotentialTherapeutic TargetPrincipal Investigator
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
Development of an auxiliary liver using a small intestinal segment packed together with liver microfragments and greater omentum
- Principal Investigator
  
  KOGURE Kimitaka
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University
Study on the bio-active molecule, DIF, found in the soil micro-organism Dictyostelium discoideum
- Principal Investigator
  
  KUBOHARA Yuzuru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Gunma University
膵β細胞に発現する甘味受容体:その機能と臨床的意義の解明Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
有茎腸管充填式肝直接肝細胞・肝組織移植法の開発―新たな補助肝の構築をめざして
- Principal Investigator
  
  KOGURE Kimitaka
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University
The role of Activin-Follistatin System in Diabetic Retinopathy
- Principal Investigator
  
  KISHI Shouji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Gunma University
Analysis of the mechanisms of the actions of DIF, a bio-active compound isolated from a soil micro-organism, and development of effective DIF derivatives
- Principal Investigator
  
  KUBOHARA Yuzuru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Gunma University
新しいインスリンの標的分子TRPV2:インスリン作動性チャネルの生理的意義の確立Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
Establishment of Therapeutic Approaches by Modification of the Activin-Follistatin System.Principal Investigator
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  Gunma University
フォリスタチンを用いた新しい肺線維症治療法の確立Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Gunma University
Analysis of the mechanisms of the actions of DIF-1 and its derivatives, anti-tumor agents isolated from Dictyostelium
- Principal Investigator
  
  KUBOHARA Yuzuru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Gunma University
難治性末梢血管障害に対する新しい治療法の開拓 -アクチビンを用いた血管新生療法-
- Principal Investigator
  
  後藤文夫
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Gunma University
爆発的に増殖する肝上皮性幹様細胞の大量培養法の確立とそれを応用した人工肝臓の作成
- Principal Investigator
  
  KOGURE Kimitaka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University
Regenerative Medicine for the Type 2 DiabetesPrincipal Investigator
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
Analysis of the actions and the action mechanism of DIF, an anti-tumor agent isolated from a soil microorganism
- Principal Investigator
  
  KUBOHARA Yuzuru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Gunma University
Activin-follistatin system as atarget for the treatment of renal failure
- Principal Investigator
  
  NOJIMA Yoshihisa
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Gunma University
Analysis of calcium channels roles in cancer cells proliferation
- Principal Investigator
  
  NAGASAWA Masahiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Gunma University
肝・胆・膵系ステムセル・バイオロジーと臓器再生医療への展開
- Principal Investigator
  
  杉山俊博
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Akita University
骨髄細胞から膵β細胞を作るPrincipal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
Reconstruction of the hepatic tissue exploiting the stem cells of the adult liver.
- Principal Investigator
  
  KOGURE Kimitaka
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University
Regeneration Therapy Diabetes Using the Pancreatic Stem Cell SystemPrincipal Investigator
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Institute for Molecular and Cellular Regulation, Gunma University
Promotion of Renal Tubular Regeneration by FollistatinPrincipal Investigator
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Institute for Molecular and Cellular Regulation, Gunma University
カルシウム透過性チャネルを標的とした血管平滑筋増殖制御法の確立Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Gunma University
増殖因子により活性化されるカルシラム透過性チャネルの研究Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
膵臓幹細胞の細胞生物学の確立Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
血管の発生分化と病態形成
- Principal Investigator
  
  永井良三
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
増殖因子により活性化されるカルシウム透過性チャネルの研究Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Gunma University
肝・胆・膵系幹細胞の発生・分化・再生の分子機構
- Principal Investigator
  
  杉山俊博
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Akita University
Mechanism of Differentiation of Pancreatic β CellsPrincipal Investigator
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
A DEVELOPMENT OF THE HEPATOCYTE TRANSPLANTATION THERAPY USING THE LIVER STEM-LIKE CELLS DIFFERENCIATED BY CELL BIOTHECNOLOGY
- Principal Investigator
  
  KOGURE Kimitaka
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University Faculty of Medicine
Identification of receptor of anti-tumor factor DIF and development of new DIF-analogs
- Principal Investigator
  
  HOSAKA Kohei
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Gunma University
細胞増殖を調節するカルシウム透過性チャネルの研究Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Gunma University
カルシウム透過性チャネルを標的とした血管平滑筋細胞増殖制御法の確立Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Gunma University
腎糸球体形成の分子機構の解明Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Gunma University
Development of a cell-free system for study of insulin action
- Principal Investigator
  
  SHIBATA Hiroshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
増殖因子によって活性化されるカルシウム透過性チャネルの研究Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
増殖因子によって活性化されるカルシウム透過性チャネルの研究Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
カルシウム透過性チャネルの制御による血管平滑筋細胞増殖のコントロールPrincipal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
A DEVELOPMENT OF THE NEW METHOD WHICH ACCELERATES LIVER REGENERATION BY USING ADENOVIRUS EXPRESSION VECTOR SYSTEM
- Principal Investigator
  
  KOGURE Kimitaka
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University
Regeneration of Pancreatic β-cellsPrincipal Investigator
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University
増殖因子によって活性化されるカルシウム透過性チャネルの制御機構Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
増殖因子によって活性化されるカルシウム透過性チャネルの研究Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
Differentiation of Pancreatic Endocrine CellsPrincipal Investigator
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University
A DEVELOPMENT OF THE NEW METHOD WHICH ACCELERATES LIVER REGENERATION BY USING PEPTIDE TECHNOLOGY
- Principal Investigator
  
  KOGURE Kimitaka
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University School of Medicine
細胞増殖調節・癌化のシグナル伝達とカルシウム透過性イオンチャネルPrincipal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
A DEVELOPMENT OF THE NEW METHOD WHICH ACCELERATES LIVER REGENERATION BY USING FOLLISTATIN,A SPECIFIC BINDING PROTEIN OF ACTIVIN A
- Principal Investigator
  
  KOGURE Kimitaka
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University
インスリンの糖取込み促進作用とGTP結合蛋白Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
Molecular Biology of B-Cells of Pancreatic Islets of Langerhans : Basic Study to develop Gene Therapy for Diabetes
- Principal Investigator
  
  ITAKURA Mituo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  内分泌・代謝学
- Research Institution
  The University of Tokushima
Development of New Anti-diabetic Peptide Drug
- Principal Investigator
  
  SHIBATA Hiroshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Institute for Molecular and Cellular Regulation, Gunma University
カルシトニン遺伝子を組み込んだ細胞医薬
- Principal Investigator
  
  TAKEUCHI Toshiyuki
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Gunma University
血管内皮平滑筋連関におけるアクチビンの役割に関する研究Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
インスリンの糖取込促進作用とGTP結合蛋白Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
Local Regulation of Endocrine Organ by Members of TGF familyPrincipal Investigator
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University
Development of Therapentic Method to Promote Liver Regeneration by Modulating the Activin-Follistatin SystemPrincipal Investigator
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Gunma University
Development of receptor antagonists to neuropeptide Y,galanin and pancreastatin
- Principal Investigator
  
  TATEMOTO Kazuhiko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University
内皮血管平滑筋連関におけるアクチビンの役割に関する研究Principal Investigator
- Principal Investigator
  
  小島至
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
Search for novel hormones and neuropeptides
- Principal Investigator
  
  TATEMOTO Kazuhiko
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University
Studies on the action of activin APrincipal Investigator
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University
Mechanism of Action of Insulin-like Growth FactorPrincipal Investigator
- Principal Investigator
  
  KOJIMA Itaru, 貴田岡正史
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University
  The University of Tokyo
情報伝達系不全による病態に関する研究
- Principal Investigator
  
  尾形悦郎
- Project Period (FY)
  1987 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  内分泌・代謝学
- Research Institution
  The University of Tokyo
インスリン様増殖因子の細胞内シグナル調節制御機構の解析
- Principal Investigator
  
  西本育夫
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
インスリン様増殖因子による細胞増殖調節機構の解明
- Principal Investigator
  
  西本育夫
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ホルモン作用機構におけるCaイオンの役割
- Principal Investigator
  
  尾形悦郎
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokyo

[Book] 膵β細胞に発現する甘味受容体とインスリン分泌2012
- Author(s)
  小島至、中川祐子
- Publisher
  内分泌代謝糖尿病
- Data Source
  KAKENHI-PROJECT-23659466
[Book] 膵β細胞に発現する甘味受容体2011
- Author(s)
  小島至、中川祐子
- Publisher
  実験医学
- Data Source
  KAKENHI-PROJECT-23659466
[Book] 群馬に多い病気~生活習慣病を知り、克服する2007
- Author(s)
  小島至、久保原禅(他7名)、ブックレット群馬大学1
- Total Pages
  72
- Publisher
  上毛新聞社刊
- Data Source
  KAKENHI-PROJECT-19590136
[Book] 群馬に多い病気〜生活習慣病を知り、克服する2007
- Author(s)
  小島至, 他
- Total Pages
  72
- Publisher
  上毛新聞出版局
- Data Source
  KAKENHI-PROJECT-19590136
[Journal Article] Return of the glucoreceptor: Glucose activates the glucose-sensing receptor T1R3 and facilitates metabolism in pancreatic β-cellls.2015
- Author(s)
  Kojima, I., Nakagawa, Y., Ohtsu, Y., Hamano, K., Medina, J., and Nagasawa, M
- Journal Title
  
  J Diab Invest
  
  Volume: 6 Issue: 3 Pages: 256-263
- DOI
  10.1111/jdi.12304
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670431
[Journal Article] Glucose promotes its own metabolism by acting on the cell-surface glucose-sensing receptor T1R32014
- Author(s)
  Nakagawa Y, Ohtsu Y, Nagasawa M, Shibata H, Kojima I
- Journal Title
  
  Endocr J
  
  Volume: 61 Issue: 2 Pages: 119-131
- DOI
  10.1507/endocrj.EJ13-0431
- NAID
  130004718269
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390245, KAKENHI-PROJECT-25670431
[Journal Article] Reconfirmation of the anatomy of the left triangular ligament and the appendix fibrosa hepatis in human livers, and its implication in abdominal surgery2014
- Author(s)
  Kimitaka Kogure, Itaru Kojima, Hiroyuki Kuwano, Toshiyuki Matsuzaki, Hiroshi Yorifuji, Kuniaki Takata, Masatoshi Makuuchi
- Journal Title
  
  Journal of Hepato-Biliary Pancreatic Science
  
  Volume: 21 Issue: 12 Pages: 856-863
- DOI
  10.1002/jhbp.144
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25670568
[Journal Article] Diverse signaling systems activated by the sweet taste-sensing recptor in human GLP-1-secreting cells2014
- Author(s)
  Otsu,Y., Nakagawa,Y., Nagasawa,M., Takeda,S., Arakawa,H. and Kojima,I
- Journal Title
  
  Mol. Cell. Endocrinol
  
  Volume: 394 Issue: 1-2 Pages: 70-79
- DOI
  10.1016/j.mce.2014.07.004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670431
[Journal Article] Expression of the glucose-sensing receptor T1R3 in pancreatic islet: changes in the expression levels in various nutritional and metabolic states2014
- Author(s)
  Medina, A., Nakagawa,Y., Ma, J.H., Li L,F., Hamano, K., Akimoto, T., Ninomiya,Y., Kojima,I
- Journal Title
  
  Endocr J
  
  Volume: 61 Issue: 8 Pages: 797-805
- DOI
  10.1507/endocrj.EJ14-0221
- NAID
  130004443983
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670431
[Journal Article] Sweet taste-sensing receptor expressed in pancreatic ・-cells : Sweet molecules act as biased agonists2014
- Author(s)
  Kojima I, Nakagawa Y, Ohtsu Y, Madina A, Nagasawa M
- Journal Title
  
  Endocr Metab
  
  Volume: 29 Issue: 1 Pages: 12-19
- DOI
  10.3803/enm.2014.29.1.12
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390245, KAKENHI-PROJECT-25670431
[Journal Article] Glucose promotes its own metabolism by acting on the cell-surface glucose-sensing receptor T1R3.2014
- Author(s)
  Nakagawa,Y., Ohtsu,Y., Nagasawa,M., Shibata,H. and Kojima,I
- Journal Title
  
  Endocr J
  
  Volume: 61 Pages: 119-131
- NAID
  130004718269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390245
[Journal Article] Involvement of the parasympathetic nervous system in the initiation of regeneration of pancreatic b-cells2013
- Author(s)
  Medina, A., Yamada,S., Hara,A., Hamamoto,K. and Kojima,I.
- Journal Title
  
  Endocr J
  
  Volume: 60 Pages: 687-696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390245
[Journal Article] Multimodal function of the sweet taste receptor expressed in pancreatic b-cells: generation of diverse patterns of intracellular signals by sweet agonists.2013
- Author(s)
  Nakagawa,Y., Nagasawa,M., Mogami,H., Lohse,M., Ninomiya,Y., and Kojima, I.
- Journal Title
  
  Endocr J
  
  Volume: 60 Pages: 1191-1206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670431
[Journal Article] Multimodal function of the sweet taste receptor expressed in pancreatic β-cells: generation of diverse patterns of intracellular signals by sweet agonists2013
- Author(s)
  Nakagawa Y, Nagasawa M, Mogami H, Lohse M, Ninomiya Y, Kojima I
- Journal Title
  
  Endocr J
  
  Volume: 60 Issue: 10 Pages: 1191-1206
- DOI
  10.1507/endocrj.EJ13-0282
- NAID
  130004770393
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249081, KAKENHI-PROJECT-23390245, KAKENHI-PROJECT-24604004
[Journal Article] Multimodal function of the sweet taste receptor expressed in pancreatic ・-cells : generation of diverse patterns of intracellular signals by sweet agonists2013
- Author(s)
  Nakagawa Y, Nagasawa M, Mogami H, Lohse M, Ninomiya Y, Kojima I
- Journal Title
  
  Endocr J
  
  Volume: 60 Pages: 1191-1206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390245
[Journal Article] Novel regulatory function of sweet taste-sensing receptor in adipogenic differentiation of 3T3-L1 cells2013
- Author(s)
  Masubuchi Y, Nakagawa Y, Ma J, Sasaki S, Kitamura T, Yamamoto Y, Kurose H, Kojima I, Shibata H
- Journal Title
  
  PLoS ONE
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390245
[Journal Article] 有茎分節腸管内肝組織片充填式補助肝臓の開発-第1報2013
- Author(s)
  小暮公孝、石崎政利、根本雅明、桑野博行、小島至、磯村寛樹、星野洪郎、幕内雅敏
- Journal Title
  
  北関東医学
  
  Volume: vol.63, No2 Pages: 133-140
- NAID
  130003368238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659636
[Journal Article] 有茎分節腸管内肝組織片充填式補助肝臓の開発―第１報2013
- Author(s)
  小暮公孝、石崎政利、根本雅明、桑野博行、小島　至、磯村寛樹、星野洪郎、幕内雅敏
- Journal Title
  
  THE KITAKANTO MEDICAL JOURNAL(北関東医学)
  
  Volume: 63(2) Pages: 133-140
- NAID
  130003368238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670568
[Journal Article] 有茎分節腸管内肝組織片充填式補助肝臓の開発(第２報)―大網共充填の効果―2013
- Author(s)
  小暮公孝、石崎政利、根本雅明、桑野博行、小島　至、磯村寛樹、星野洪郎、幕内雅敏
- Journal Title
  
  THE KITAKANTO MEDICAL JOURNAL(北関東医学)
  
  Volume: 63(3) Pages: 223-232
- NAID
  130003368247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670568
[Journal Article] A novel regulatory function of sweet taste-sensing receptor in adipogenic differentiation of 3T3-L1 Cells.2013
- Author(s)
  Masubuchi Y., Nakagawa Y., Ma J., Sasaki T., Kitamura T., Yamamoto Y., Kurose H., Kojima I and Shibata H.
- Journal Title
  
  PLOS ONE
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670431
[Journal Article] Multimodal function of the sweet taste receptor expressed in pancreatic b-cells: generation of multiple patterns of intracellular signals by sweet agonists2013
- Author(s)
  Nakagawa Y, Nagasawa M, Mogami H, Lohse M, Ninomiya Y, Kojima I
- Journal Title
  
  Endocr J
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659466
[Journal Article] A novel regulatory function of sweet taste-sensing receptor in adipogenic differentiation of 3T3-L1 Cells.2013
- Author(s)
  Masubuchi Y., Nakagawa Y., Ma J., Sasaki T., Kitamura T., Yamamoto Y., Kurose H., Kojima I and Shibata H.
- Journal Title
  
  PLOS ONE
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390245
[Journal Article] Involvement of the parasympathetic nervous system in the initiation of regeneration of pancreatic beta-cells2013
- Author(s)
  Medina, A., Yamada,S., Hara,A., Hamamoto,K. and Kojima,I.
- Journal Title
  
  Endocr J
  
  Volume: 60 Pages: 687-696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670431
[Journal Article] Novel regulatory function of sweet taste-sensing receptor in adipogenic differentiation of 3T3-L1 cells2012
- Author(s)
  Masubuchi Y, Nakagawa Y, Ma J, Sasaki S, Kitamura T, Yamamoto Y, Kurose H, Kojima I, Shibata H
- Journal Title
  
  PLoS ONE
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659466
[Journal Article] The role of the sweet taste receptor in enteroendocrine cells and pancreatic ・-cells2011
- Author(s)
  Kojima I, Nakagawa Y
- Journal Title
  
  Diab Metab J
  
  Volume: 35 Issue: 5 Pages: 451-457
- DOI
  10.4093/dmj.2011.35.5.451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390245
[Journal Article] The role of the sweet taste receptor in enteroendocrine cells and pancreatic-cells2011
- Author(s)
  Kojima I, Nakagawa Y
- Journal Title
  
  Diabetes Metab
  
  Volume: J35 Pages: 451-457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659466
[Journal Article] 膵β細胞に発現する甘味受容体2011
- Author(s)
  小島至、中川祐子
- Journal Title
  
  実験医学
  
  Volume: 29 Pages: 1215-1219
- Data Source
  KAKENHI-PROJECT-23659466
[Journal Article] The role of the sweet taste receptor in enteruendocrine cells and pancreatic β-cells2011
- Author(s)
  Kojima I, Nakagawa Y
- Journal Title
  
  Diabetes Metab J
  
  Volume: 34 Pages: 451-457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390245
[Journal Article] 膵β細胞に発現する甘味受容体2010
- Author(s)
  小島至、中川祐子
- Journal Title
  
  実験医学
  
  Volume: 29 Pages: 1215-1219
- Data Source
  KAKENHI-PROJECT-21659226
[Journal Article] Extracellular Matrix Modulates Insulin Production During Differentiation of AR42J Cells : Functional Role of Pax6 Transcription Factor.2010
- Author(s)
  Hamamoto,K., Yamada,S., Hara,A., Kodera,T., Seno,M., Kojima,I
- Journal Title
  
  Journal of Cellular Biochemistry
  
  Volume: 112 Pages: 318-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659226
[Journal Article] Regulation of Calcium-permeable TRPV2 Channel by Insulin in Pancreatic β-Cells.2009
- Author(s)
  E Hisanaga, M Nagasawa, K Ueki, RN Kulkarni, M Mori and I Kojima
- Journal Title
  
  Diabetes 58
  
  Pages: 174-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659233
[Journal Article] Sweet taste receptor expressed in pancreatic β cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion.2009
- Author(s)
  Nakagawa Y, Nagsawa M, Yamada S, Hara A, Mogami H, Nikolaev VO, Lohse MJ, Shigemura N, Ninomiya Y, Kojima I
- Journal Title
  
  PLoS ONE 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659226
[Journal Article] Identification of differentially express genes induced during the proliferative response of the liver induced by follistatin.2009
- Author(s)
  Medina J., Yamada S., Kojima I.
- Journal Title
  
  Endocrine J. 56
  
  Pages: 1067-1077
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592032
[Journal Article] Proteomic analysis identifies proteins that continue to grow hepatic stem-like cells without differentiation2008
- Author(s)
  Saheki, T., Ito, H., Sekiguchi, A., Sugiyama, T., Izumi, T. and Kojima, I.
- Journal Title
  
  Cytotechnology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] A betacellulin mutant promotes differentiation of pancreatic acinar AR42J cells into insulin-producing cells with low affinity of binding to ErbB12008
- Author(s)
  Nagaoka, T., Fukuda, T., Hashizume, T., Nishiyama, T., Tada, H., Yamada, H., Salomon, D. S., Yamada, S., Kojima, L, and Seno, M.
- Journal Title
  
  J. Mol. Biol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] 前駆細胞、組織幹細胞2008
- Author(s)
  山田聡子、小島至
- Journal Title
  
  膵遺伝子MOOK
  
  Pages: 67-71
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Reversal of streptozotocin-induced hyperglycemia by continuous supply of betacellulin in mice2008
- Author(s)
  Yamamoto, Y., Yamada, S., Kodera, T., Hara, A., Motoyoshi, K., Tanaka,Y. Nagaoka, T., Seno, M. and Kojima, I.
- Journal Title
  
  Growth Factor (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] MafA regulates expression of genes important to islet beta cell function2007
- Author(s)
  Matsuoka, T. A., Kaneto, H., Stein, R., Miyatsuka, T., Kawamori, D., Henderson,E., Kojima, I., Mastuhisa, M., Hon, M. and Yamasaki, Y.
- Journal Title
  
  Mol. Endocrinol 21
  
  Pages: 2764-2774
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Ptfl and RBP-J cooperate in activati ng Pdxl gene expression through binding to Area III2007
- Author(s)
  Miyatsuka, T., Matsuoka, T. A., Shiraiwa, T., Yamamoto, T., Kojima, I. and Kaneto, H.
- Journal Title
  
  Biochem. Biophys. Res. Commun 362
  
  Pages: 905-909
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Activin A as a critical mediator of capillary formation: interaction with the fibroblast growth factor action2007
- Author(s)
  Hayashi, Y., Maeshima, K., Goto, F. and Kojima, I.
- Journal Title
  
  Endocrine J 54
  
  Pages: 311-318
- NAID
  10019478877
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] 先端の治療戦略糖尿病の再生医療現状と未来2007
- Author(s)
  濱本耕平、小島至
- Journal Title
  
  最新医学 62
  
  Pages: 949-956
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Dictyostelium differentiation-inducing factor-1 induces glucose transporter 1 translocation and promotes glucose uptake in mammalian cells2007
- Author(s)
  Omata W, Shibata H, Nagasawa M,Kojima I, Kikuchi H, Oshima Y, Hosaka K,& Kubohara Y
- Journal Title
  
  FEBS Journal 274
  
  Pages: 3392-3404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590136
[Journal Article] A ra pancreatic islet is formed by unification of multiple endocrine cell clusters2007
- Author(s)
  Hara, H., Kabeya, Y., Kojima, I. and Yamashina, S.
- Journal Title
  
  Dev. Dynam 236
  
  Pages: 3451-3458
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Conophylline and betacellulin-□4: effective combination to promote differentiation of pancreatic β cells2007
- Author(s)
  Kitamura, R., Ogata, T., Tanaka, Y., Seno, M., Umezawa, K., Taki, I., and Kojima, I.
- Journal Title
  
  Endocrine J 54
  
  Pages: 255-264
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Regeneration Therapy for Diabetes2007
- Author(s)
  Hamamoto, K., Kojima I.
- Journal Title
  
  Saisin Igaku 62
  
  Pages: 949-956
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Somatic Stem Cell2007
- Author(s)
  Yamada, S., Kojima, I.
- Journal Title
  
  Idenshi MOOK (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Activation of Endogenous Stem Cell System2006
- Author(s)
  Yamada, S., Kojima, I.
- Journal Title
  
  Saisin Igaku 62
  
  Pages: 1515-1520
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Development of a novel β cell specific promotor system for the identification of insulin producing cells in in vitro cell cultures2006
- Author(s)
  Fukazawa, T., Matsuoka, J., Naomoto, Y., Nakai, T., Darbin, M., Kojima, I., Lakey, JRT., Tanaka, N.
- Journal Title
  
  Exp. Cell Res 312
  
  Pages: 3404-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Regeneration Medicine for Pancreatic β Cells2006
- Author(s)
  Yamada, S., Kojima, I.
- Journal Title
  
  Mebio 22
  
  Pages: 54-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] 糖尿病の再生医学2006
- Author(s)
  山田聡子、小島至
- Journal Title
  
  Mebio 22
  
  Pages: 54-60
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Activin or lollistatin : Which is more beneficial to support liver regeneration after massive hepatectomy?2006
- Author(s)
  Endo, D., Maku-uchi, M., Kojima, I.
- Journal Title
  
  Endocrine J 53
  
  Pages: 73-78
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Regeneration Medicine of Pancreatic β Cells2006
- Author(s)
  Yamada, S., Kojima, I.
- Journal Title
  
  Tounyoubyousinndan Q & A
  
  Pages: 386-388
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] 糖尿病再生医療の現状と未来2006
- Author(s)
  山本頼綱、小島至
- Journal Title
  
  糖尿病学の進歩 40
  
  Pages: 239-244
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Activin A-induced expression of PAX4 in AR42J-B13 cells involves the increase in transactivation of E47/E12.2006
- Author(s)
  Kanno, R., Ogihara, T., Igarashi, Y., Tanaka, Y., Smith, S.B., Kojima, I., German, M.S., Kawamori, R., Watada, H.
- Journal Title
  
  Biochim. Biochem. Acta 1759
  
  Pages: 44-50
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] 糖尿病の再生医療、現状と展望2006
- Author(s)
  山本頼綱、小島至
- Journal Title
  
  糖尿病学の進歩2006
  
  Pages: 239-244
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Regulation Therapy for Diabetes2006
- Author(s)
  Kodera, T., Kojima I.
- Journal Title
  
  Diabetes Frontier 17
  
  Pages: 308-313
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] 糖尿病の再生医療2006
- Author(s)
  小寺力、小島至
- Journal Title
  
  Diabetes Frontier 17
  
  Pages: 308-313
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Development of a novel β cell specific promoter system for the identification of insulin producing cells in in vitro cell cultures.2006
- Author(s)
  Fukazawa, T., Matsuoka, J., Naomoto, Y., Nakai, T., Darbin, M., Kojima, I., Lakey, JRT., Tanaka, N.
- Journal Title
  
  Exp.Cell.Res 312
  
  Pages: 3404-3412
- Data Source
  KAKENHI-PROJECT-17659243
[Journal Article] 内在性幹細胞の賦活化2006
- Author(s)
  山田聡子、小島至
- Journal Title
  
  最新医学 61
  
  Pages: 1515-1520
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Transcription factors Regulating development of pancreatic β cells2006
- Author(s)
  Hara, A., Kojima I.
- Journal Title
  
  Tounyoubyou Taisyaka 23
  
  Pages: 95-100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] GLP-1 activates protein kinase C through Ca2+-dependent activation of phospholipase C in insulin-secreting cells.2006
- Author(s)
  Suzuki, Y., Zhang, H., Saito, N., Kojima, I., Urano, T., Mogami, H.
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 28499-28507
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Strategy for Regeneration Medicine2006
- Author(s)
  Yamada, S., Kojima, I.
- Journal Title
  
  Igaku no Ayumi 217
  
  Pages: 381-385
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] 細胞移植による糖尿病治療2006
- Author(s)
  山田聡子、小島至
- Journal Title
  
  細胞 38
  
  Pages: 115-117
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] 膵β細胞の再生医療2006
- Author(s)
  山田聡子、小島至
- Journal Title
  
  糖尿病診療Q&A
  
  Pages: 386-388
- NAID
  10018656361
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Activin A-induced expression of PAX4 in AR42J-B13 cells involves the increase in transactivation of E47/E122006
- Author(s)
  Kanno, R., Ogihara, T., Igarashi, Y., Tanaka, Y., Smith, S. B., Kojima, I., German, M. S., Kawamori, R. and Watada, H.
- Journal Title
  
  Biochim. Biochem. Acta 1759
  
  Pages: 44-50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] In vitro transdifferentiation of mature hepatocytes into insulin-producing cells2006
- Author(s)
  Yamada, S., Yamamoto, Y., Nagasawa, M., Hara, A., Kodera, T. and Kojima, I.
- Journal Title
  
  Endocrine J 53
  
  Pages: 789-795
- NAID
  10020612590
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Regeneration Therapy for Diabetes2006
- Author(s)
  Yamamoto, Y., Kojima I.
- Journal Title
  
  Tounyoubyougaku no sinpo
  
  Pages: 239-244
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Cell Transplantation for Treatment of Diabetes2006
- Author(s)
  Yamada, S., Kojima, I.
- Journal Title
  
  Saibou 38
  
  Pages: 115-117
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] GLP-1 activates protein kinase C through Ca^<2+> - dependent activation of phospholipase C in insulin-secreting cells2006
- Author(s)
  Suzuki, Y., Zhang, H., Saito, N., Kojima, I., Urano, T. and Mogami, H.
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 28499-507
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] 幹細胞による膵再生と実用化への戦略2006
- Author(s)
  山田聡子、小島至
- Journal Title
  
  医学のあゆみ 217
  
  Pages: 381-385
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] In vitro transdifferentiation of mature hepatocytes into insulin-producing cells.2006
- Author(s)
  Yamada, S., Yamamoto, Y., Nagasawa, M., Hara, A., Kodera, T., Kojima, I.
- Journal Title
  
  Endocrine J 53
  
  Pages: 785-795
- NAID
  10020612590
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Development of a novel β cell specific promoter system for the identification of insulin producing cells in vitro cell cultures.2006
- Author(s)
  Fukazawa, T., Matsuoka, J., Naomoto, Y., Nakai, T., Darbin, M., Kojima, I., Lakey, JRT., Tanaka, N.
- Journal Title
  
  Exp. Cell Res. 312
  
  Pages: 3404-3412
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Regeneration Therapy for Diabetes2006
- Author(s)
  Yamamoto, Y., Kojima, I.
- Journal Title
  
  Tounyoubyougaku no sinpo
  
  Pages: 239-244
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Activin A-induced expression of PAX4 in AR42J-B13 cells involves the increase in transactivation of E47/E12.2006
- Author(s)
  Kanno, R., Ogihara, T., Igarashi, Y., Tanaka, Y., Smith, S.B., Kojima, I., German, M.S., Kawamori, R., Watada, H.
- Journal Title
  
  Biochim.Biochem.Acta 1759
  
  Pages: 44-50
- Data Source
  KAKENHI-PROJECT-17659243
[Journal Article] 膵β細胞の発生・分化と転写因子2006
- Author(s)
  原朱美。小島至
- Journal Title
  
  内分泌・糖尿病代謝科 23
  
  Pages: 95-100
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Attenuation of bleomycin-induced pulmonary fibrosis by follistatin.2005
- Author(s)
  Aoki F, Kurabayashi M, Hasegawa Y, Kojima I.
- Journal Title
  
  Am.J.Respir.Crit.Care.Med 172
  
  Pages: 713-720
- Data Source
  KAKENHI-PROJECT-17659243
[Journal Article] Activin A augments vascular endothelial growth factor activity in promoting branching tubulogenesis in hepatic sinusoidal endothelial cells.2004
- Author(s)
  Daisuke Endo, Kimitaka Kogure, Yoshihisa Hasegawa, Masatoshi Makuuchi, Itaru Kojima
- Journal Title
  
  Journal of Hepatology 40
  
  Pages: 399-404
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370375
[Journal Article] Activin A is a potent activator for renal interstitial fibroblasts.2004
- Author(s)
  Yamashita S, Maeshima A, Kojima I, Nojima Y.
- Journal Title
  
  J Am Soc Nephrol 15
  
  Pages: 91-101
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590842
[Journal Article] A device of the isolation of epithelial stem like cells from rat liver.2004
- Author(s)
  Kimitaka Kogure^1 Hiroyuki Kuwano, Hiroo Hoshino, Itaru Kojima
- Journal Title
  
  The 12^<th> United European Gastroenterology Week(UEGW), Prague, Czech Republic 9
  
  Pages: 25-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370375
[Journal Article] A device of the separation of the rat liver sinusoidal endothelial cells and the culture in the three-dimensional matrix.2003
- Author(s)
  Kimitaka Kogure, Masaaki Nemoto, Masatoshi Ishizaki, Fumio Arisawa, Kenichi Nomoto, Hideki Suzuki, Hiroyuki Kuwano, Itaru kojima, Daisuke Eendo, Masatoshi Makuuchi
- Journal Title
  
  11th Congress of the European Society for Organ Transplantation. Venice, Italy 9
  
  Pages: 21-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370375
[Journal Article] A simple method to induce differentiation of murine bone marrow mesenchymal cells to insulin-producing cells using conophylline and betacellulin-δ4
- Author(s)
  Hisanaga, E., Park, K. Y., Yamada, S., Hashimoto, H., Takeuchi, T, Mori, M., Seno, M., Umezawa, K., Takei, I. and kojima, I.
- Journal Title
  
  Endocrine J (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Journal Article] Conophylline and betacellulin-d4 : effective combination to promote differentiation of pancreatic β cells.
- Author(s)
  Kiamura, R., Ogata, T., Tanaka, Y., Seno, M., Umezawa, K., Taki, I., Kojima, I.
- Journal Title
  
  Endocrine J (in press)
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] 人肝９３例の門脈肝後区域枝の分岐形態の検討2016
- Author(s)
  小暮公孝、小島至、根本雅明、石崎政利、新木健一郎、桑野博之、幕内雅敏
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪市（大阪国際会議場）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15K15489
[Presentation] 左三角間膜(left triangular ligament: LTL)と肝繊維付属（appendix fibrosa hepatis: AFH）の解剖学的関係の再確認―腹部外科における要点―2015
- Author(s)
  小暮公孝、小島　至、石崎政利、根本雅明、桑野博之、松崎利行、依藤　宏、高田邦昭、磯村寛樹、幕内雅敏
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋市（名古屋国際会議場）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-15K15489
[Presentation] 左三角間膜(left triangular ligament: LTL)と肝繊維付属（appendix fibrosa hepatis: AFH）の解剖学的関係の再確認―腹部外科における要点―2015
- Author(s)
  小暮公孝、小島　至、石崎政利、根本雅明、桑野博之、松崎利行、依藤　宏、高田邦昭、磯村寛樹、幕内雅敏
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋市（名古屋国際会議場）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-25670568
[Presentation] グルコース感知受容体によるインスリン分泌の制御2014
- Author(s)
  小島至、中川祐子
- Organizer
  第８７回日本内分泌学会総会
- Place of Presentation
  福岡市福岡国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-23390245
[Presentation] グルコース感知受容体T1R3によるインスリン分泌の制御2014
- Author(s)
  小島至、中川祐子
- Organizer
  第８７回日本内分泌学会総会
- Place of Presentation
  福岡市福岡国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-25670431
[Presentation] グルコース感知受容体によるインスリン分泌の制御2014
- Author(s)
  小島至, 中川祐子
- Organizer
  第87回日本内分泌学会総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-23390245
[Presentation] 膵β細胞におけるグルコース感知受容体T1R3の発現変化2014
- Author(s)
  中川祐子、Anya Medina、濱野邦久、大津義晃、李龍飛、馬金輝、小島至
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪府大阪市大阪国際会議場
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25670431
[Presentation] グルコース感知受容体T1R3による糖代謝の促進機構2014
- Author(s)
  大津義晃、中川祐子、濱野邦久、李龍飛、荒川浩一、小島至
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪府大阪市大阪国際会議場
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25670431
[Presentation] 甘味刺激によるGs活性化は微小管脱重合とRho活性化を介して脂肪分化を抑制する2013
- Author(s)
  増渕洋祐、中川祐子、馬金輝、長澤雅裕、小島至、柴田宏
- Organizer
  第５６回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本市熊本市民会館
- Data Source
  KAKENHI-PROJECT-23390245
[Presentation] 甘味刺激による Gs 活性化は微小管脱重合と Rho 活性化を介して脂肪分化を抑制する2013
- Author(s)
  増淵洋祐、中川祐子、馬金輝、長澤雅裕、小島至、柴田宏
- Organizer
  第56回日本糖尿病学会総会
- Place of Presentation
  熊本市
- Year and Date
  2013-05-15
- Data Source
  KAKENHI-PROJECT-23659466
[Presentation] GLP-1産生細胞における甘味受容体のシグナル産生機構2013
- Author(s)
  大津義晃、中川祐子、荒川浩一、小島至
- Organizer
  第５６回日本糖尿病学会年時学術集会
- Place of Presentation
  熊本市熊本市民会館
- Data Source
  KAKENHI-PROJECT-23390245
[Presentation] GLP-1産生細胞における甘味受容体シグナル産生機構:アセスルファームKの細胞内Ca2+低下作用の解析2013
- Author(s)
  大津喜晃、中川祐子、荒川浩一、小島至
- Organizer
  第56回日本糖尿病学会総会
- Place of Presentation
  熊本市
- Year and Date
  2013-05-15
- Data Source
  KAKENHI-PROJECT-23659466
[Presentation] グルコース作用における甘味受容体の関与2013
- Author(s)
  中川祐子、長澤雅裕、最上秀夫、小島至
- Organizer
  第５６回に本糖尿病学会年次学術集会
- Place of Presentation
  熊本市熊本市民会館
- Data Source
  KAKENHI-PROJECT-25670431
[Presentation] GLP1産生細胞における甘味受容体のシグナル産生機構2013
- Author(s)
  大津義晃, 中川祐子, 荒川浩一, 小島至
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本
- Year and Date
  2013-05-16
- Data Source
  KAKENHI-PROJECT-23390245
[Presentation] 甘味刺激によるGs活性化は微小間重合とRho活性化を介して脂肪分化を抑制する2013
- Author(s)
  増渕洋祐、中川祐子、馬金輝、長澤雅裕、小島至、柴田宏
- Organizer
  第５６回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本市熊本市民会館
- Data Source
  KAKENHI-PROJECT-25670431
[Presentation] GLP1産生細胞における甘味受容体の「シグナル産生機構2013
- Author(s)
  大津義晃、中川祐子、荒川浩一、小島至
- Organizer
  第５６回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本市熊本市民会館
- Data Source
  KAKENHI-PROJECT-25670431
[Presentation] グルコース作用における甘味受容体の関与:代謝経路との連関2013
- Author(s)
  中川祐子、長澤雅裕、最上秀夫、小島至
- Organizer
  第56回日本糖尿病学会総会
- Place of Presentation
  熊本市
- Year and Date
  2013-05-15
- Data Source
  KAKENHI-PROJECT-23659466
[Presentation] 門脈血流を考慮した肝組織片充填有茎小腸グラフトの開発2013
- Author(s)
  小暮公孝、小島　至、久保憲生、新木健一郎、持田　泰、鈴木秀樹、桑野博行、磯村寛樹、星野洪郎、幕内雅敏
- Organizer
  第113回日本外科学会総会
- Place of Presentation
  福岡市　福岡国際会議場
- Data Source
  KAKENHI-PROJECT-25670568
[Presentation] グルコース作用における甘味受容体の関与2013
- Author(s)
  中川祐子、長澤雅裕、最上秀夫、小島至
- Organizer
  第５６回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本市熊本市民会館
- Data Source
  KAKENHI-PROJECT-23390245
[Presentation] Development of the small intestinal graft filled with the liver tissue in consideration of portal venous blood flow2013
- Author(s)
  小暮公孝、小島至、久保憲生、新木健一郎、持田泰、鈴木秀樹、桑野博行、磯村寛樹、星野洪郎、幕内雅敏、門脈血流を考慮した肝組織片充填有茎小腸グラフトの開発
- Organizer
  第113回日本外科学会総会
- Place of Presentation
  福岡国際会議場(福岡市)
- Data Source
  KAKENHI-PROJECT-23659636
[Presentation] グルコース作用における甘味受容体の関与2013
- Author(s)
  中川祐子, 長澤雅裕, 最上秀夫, 小島至
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本
- Year and Date
  2013-05-16
- Data Source
  KAKENHI-PROJECT-23390245
[Presentation] 甘味刺激によるGs活性化は微小管脱重合とRho活性化を介して脂肪分化を抑制する2013
- Author(s)
  増渕洋祐, 中川祐子, 馬金輝, 長澤雅裕, 小島至, 柴田宏
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本
- Year and Date
  2013-05-17
- Data Source
  KAKENHI-PROJECT-23390245
[Presentation] 膵β細胞におけるグルコース作用:代謝に依存しない cAMP シグナル産生経路の解明2012
- Author(s)
  中川祐子、長澤雅裕、最上秀夫、小島至
- Organizer
  第55回日本糖尿病学会総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2012-05-17
- Data Source
  KAKENHI-PROJECT-23659466
[Presentation] 大網を利用した肝組織片充填有茎小腸グラフトの驚異的増殖法の開発、Simultaneous insertion of the great omentum accelerates the growth of the intestinal graft packed with liver tissue2012
- Author(s)
  小暮公孝、小島至、久保憲生、新木健一郎、佐々木滋、鈴木秀樹、桑野博行、ホク・エスケー・アリフル、星野洪郎、幕内雅敏、
- Organizer
  第112回日本外科学会総会
- Place of Presentation
  幕張メッセ(千葉市)
- Data Source
  KAKENHI-PROJECT-23659636
[Presentation] GLP1-1分泌細胞HuTu-80における甘味受容体の機能解析2012
- Author(s)
  大津義晃、中川祐子、小島至
- Organizer
  第55回日本糖尿病学会総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2012-05-17
- Data Source
  KAKENHI-PROJECT-23659466
[Presentation] Appendix fibrosa hepatis(肝線維性付属物)の肉眼的、組織学的検討2012
- Author(s)
  小暮公孝、小島至、石崎政利、根本雅明、和田渉、鈴木秀樹、桑野博行、依藤宏、松崎利行、幕内雅敏
- Organizer
  第67回日本消化器外科学会
- Place of Presentation
  富山国際会議場(富山市)
- Data Source
  KAKENHI-PROJECT-23659636
[Presentation] 柴田宏甘味受容体による脂肪細胞分化抑制のシグナル機構2012
- Author(s)
  増淵洋祐、中川祐子、馬金輝、小島至
- Organizer
  第55回日本糖尿病学会総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2012-05-17
- Data Source
  KAKENHI-PROJECT-23659466
[Presentation] Multimodal function of the sweet taste receptor expressed in pancreatic b-cells2012
- Author(s)
  Kojima I
- Organizer
  The 10th International Symposium on Molecular and Neural Mechanism of taste and Olfactory Perception
- Place of Presentation
  九州大学(福岡市)
- Year and Date
  2012-11-03
- Data Source
  KAKENHI-PROJECT-23659466
[Presentation] 膵β細胞におけるグルコース作用:代謝に依存しないDAG産生経路の解明2011
- Author(s)
  中川祐子、長澤雅裕、最上秀夫、小島至
- Organizer
  第54回日本糖尿病学会総会
- Place of Presentation
  札幌
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23390245
[Presentation] The role of Activin A in Angiogenesis2011
- Author(s)
  前嶋京子、小島至、岸章治
- Organizer
  ARVO 2011 annual meeting
- Place of Presentation
  フォートローダーデール国際会議場、(フロリダ、アメリカ)
- Year and Date
  2011-05-04
- Data Source
  KAKENHI-PROJECT-20592032
[Presentation] Role of the sweet taste receptor in the action of glucose in pancreatic β-cells2010
- Author(s)
  Itaru Kojima
- Organizer
  The 8^<th> International Symposium on Molecular and Cellular Mechanism of Taste and Olfactory Perception
- Place of Presentation
  九州大学
- Year and Date
  2010-11-06
- Data Source
  KAKENHI-PROJECT-21659226
[Presentation] 膵β細胞に発現する甘味受容体の機能2009
- Author(s)
  中川祐子、長澤雅裕, 山田聡子、原朱美、最上秀夫、小島至
- Organizer
  第82回日本内分泌学会総会
- Place of Presentation
  群馬県民会館
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-21659226
[Presentation] 実験的脈絡膜新生血管とアクチビン2009
- Author(s)
  吉田いづみ、前嶋京子、小島至、岸章治
- Organizer
  第113回日本眼科学会
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2009-04-17
- Data Source
  KAKENHI-PROJECT-20592032
[Presentation] インスリン作動性カルシウム透過性チャネルTRPV2の機能と意義2008
- Author(s)
  久永悦子、長澤雅裕、岡田秀一、清水弘行、植木浩二郎、森昌朋、小島至
- Organizer
  第51回日本糖尿病学会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19659233
[Presentation] アクチビン及びフォリスタチンによる管腔形成作用2008
- Author(s)
  前嶋京子、小島至、岸章治
- Organizer
  第112回日本眼科学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2008-04-18
- Data Source
  KAKENHI-PROJECT-20592032
[Presentation] Treatment of Type 2 Diabetes By Transduction of BTC Gene2007
- Author(s)
  Yamamoto, Y., Yamada, S., Kodera, T., Hara, A., Tanaka, Y., Motoyoshi, K., Seno, M., Kojima, I.
- Organizer
  50th Japan Diabetes Society
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] 膵β細胞の再生と分化誘導因子2007
- Author(s)
  小島至
- Organizer
  第1回慶応大学ハイテクリサーチシンポジウム
- Place of Presentation
  横浜
- Year and Date
  2007-12-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Activin in Diabetes. Retinopathy2007
- Author(s)
  Maeshima, K., Takahashi, K., Kishi, A., Kojima, I.
- Organizer
  Japanese Association of Ophthalmology
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Autocrine Regulation of TRPV22007
- Author(s)
  Kojima, I., Hisanaga, E., Nagasawa, M.
- Organizer
  TRP Workshop
- Place of Presentation
  Okazaki
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Road to Realization of Regenerative2007
- Author(s)
  Kojima, I.
- Organizer
  Medicine for Diabetes
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Effect of Extracellular Matrix on Differentiation of AR42J Cells2007
- Author(s)
  Hamamoto, K., Yamada, S., Yamamoto, Y., Kodera, K., Hara, A., Seno, M., Kojima, I.
- Organizer
  50th Japan Diabetes Society
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Mechanism of Actin of Betalullin-δ42007
- Author(s)
  Yamada, S., Ishiyama, N., Seno, M., Kojima, I.
- Organizer
  50th Japan Diabetes Society
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] 糖尿病再生医療実現への道2007
- Author(s)
  小島至
- Organizer
  第16回Endocrine Bay Seminar
- Place of Presentation
  横浜
- Year and Date
  2007-10-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Betacellulin and Betacellulin δ4: Comparison of the Effects on Growth and Differentiation of Pancreatic β Cells2007
- Author(s)
  Kojima, I.
- Organizer
  5th Catholic Stem Cell Symposium
- Place of Presentation
  Seoul
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Effect of Conophylline and betacellulin-δ4 in Type Diabetic Model2007
- Author(s)
  Kodera, T., Yamamoto, Y., Hara, A., Yamada, S., Tanaka, Y., Watanabe, Y., Seno, M., Takei, I., Umezawa, K, Kojima, I.
- Organizer
  50th Japan Diabetes Society
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Establishment of Organ Culture System to Analyze the Formation of the Mantle-core Structure2007
- Author(s)
  Hara, A., Yamada, S., Yamamoto, Y., Kodera, T., Kojima, I.
- Organizer
  50th Japan Diabetes Society
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] 膵β細胞から分泌されるインスリンによるTRPV2のオートクリン調節2007
- Author(s)
  小島至他
- Organizer
  第3回TRP研究会
- Place of Presentation
  岡崎
- Year and Date
  2007-07-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] 哺乳類細胞に対するDIF-1の糖代謝促進作用2007
- Author(s)
  久保原禅、小俣和香、柴田宏、小島至、保坂公平、菊地晴久, 大島吉輝
- Organizer
  第10回細胞性粘菌研究会
- Place of Presentation
  弘前
- Year and Date
  2007-11-03
- Data Source
  KAKENHI-PROJECT-19590136
[Presentation] 哺乳類細胞に対するDIF-1およびその誘導体の糖代謝促進作用2007
- Author(s)
  久保原禅、小俣和香、柴田宏、小島至、保坂公平、菊地晴久, 大島吉輝
- Organizer
  第10回細胞性粘菌研究会
- Place of Presentation
  弘前
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-19590136
[Presentation] Involvement of Ubiquitin in Insulin-induced Degration of GRUT42007
- Author(s)
  Shibata, H., Omata, W., Kojima, I.
- Organizer
  50th Japan Diabetes Society
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Regeneration Therapy for Diabetes2007
- Author(s)
  Kojima, I.
- Organizer
  42th Progress in Diabetology
- Place of Presentation
  kanazawa
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] TRPV2: Calcium-permeable Calcium-permeable Channel2007
- Author(s)
  Hisanaga, E., Nagasawa, M., Mori, M., Kojima, I.
- Organizer
  50th Japan Diabetes Society
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Differentiation of Pancreatic β Cells2007
- Author(s)
  Kojima, I.
- Organizer
  Japanese Society for Animal Cell Technology
- Place of Presentation
  Takasaki
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Betacellulin and betacellulinδ4: comparison of the effects on growth anddiffere ntiation of pancreatic β cells.2007
- Author(s)
  Kojima, I.
- Organizer
  Catholic Stem Cell Symposium
- Place of Presentation
  ソウル
- Year and Date
  2007-06-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] 膵ランゲルハンス島β細胞の分化と膵臓の再生2007
- Author(s)
  小島至
- Organizer
  日本動物細胞土学会2007年度大会特別講演
- Place of Presentation
  高崎
- Year and Date
  2007-07-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Role of Differentiation Factors in β Cell Regeneration2007
- Author(s)
  Kojima, I.
- Organizer
  Keio University Hi-Tech Research Symposium
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] 糖尿病再生医療実現へのアプローチ2006
- Author(s)
  小島至
- Organizer
  北海道分子医学研究会
- Place of Presentation
  札幌
- Year and Date
  2006-07-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Regeneration of β cells by Transduction of Mature BTC Gene2006
- Author(s)
  Yamamoto, Y., Yamada, S., Hara, A., Nagaoka, T., Kitamura, R., Kodera, T., Yanaka, Y., Motoyoshi, K., Seno M., Kojima I.
- Organizer
  49th Japan Diabetes Society
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Differentiation of Mouse Mesenchymal Cells to Insulin-secreting Cells2006
- Author(s)
  Hisanaga, E., Yamada, S., Yamamoto, Y., Okada, S., Shimizu, H., Mori, M., Kojima, I.
- Organizer
  49th Japan Diabetes Society
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] 糖尿病再生医療の現状と展望2006
- Author(s)
  小島至
- Organizer
  第41回糖尿病学の進歩
- Place of Presentation
  札幌
- Year and Date
  2006-09-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Regeneration Medicine for Diabetes2006
- Author(s)
  Kojima, I.
- Organizer
  Molecular Diabetology Workshop
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Therapeutic Approach to Diaberes2006
- Author(s)
  Kojima, I.
- Organizer
  Hokkaido Molecular Medicine Seminar
- Place of Presentation
  Sapporo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] 糖尿病再生医療実現へのアプローチ2006
- Author(s)
  小島至
- Organizer
  第90回北九州内分泌研究会
- Place of Presentation
  北九州
- Year and Date
  2006-12-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Proteome Analysis of HSL Cells2006
- Author(s)
  Ito, H., Saeki, T., Sekiguchi, A., Nishina, A., Izumi, T., Sugiyama, T. Kojima, I.
- Organizer
  Japanese Molecular Biology Forum
- Place of Presentation
  Nagoya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Treatment of Type 2 Diabetes Using Conophylline and betacellulin -δ42006
- Author(s)
  Kodera, T., Yamamoto, Y., Hara, A., Yamada, S., Tanaka, Y., Watanabe, Y., Seno, M.,Umezawa, K., Takei, I., Kojima, I.
- Organizer
  49th Japan Diabetes Society
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] TRPV2 Expressed in MIN6 Cells2006
- Author(s)
  Hisanaga, E., Nagasawa, M., Okada, S., Shimizu, H., Mori, M., Kojima, I.
- Organizer
  49th Japan Diabetes Society
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] 糖尿病再生医療の現状と展望2006
- Author(s)
  小島至
- Organizer
  分子糖尿病研究会
- Place of Presentation
  東京
- Year and Date
  2006-10-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Realization of Regeneration Medicinie for Diabetes2006
- Author(s)
  Kojima, I.
- Organizer
  Kitakyusyu Endocrine Forum
- Place of Presentation
  Kitakyusyu
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] Analysis of Formation of the Mantle-Core Structure2006
- Author(s)
  Hara, A., Kadoya, Y., Yamashina, S., Kojima, I.
- Organizer
  49th Japan Diabetes Society
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390273
[Presentation] 有茎小腸グラフト内充填肝組織片の生着延長法の工夫
- Author(s)
  小暮公孝、小島　至、石崎政利、根本雅明、久保憲生、鈴木秀樹、桑野博行、磯村寛樹、星野洪郎、幕内雅敏
- Organizer
  第114回日本外科学会総会
- Place of Presentation
  京都府京都市国立京都国際会館
- Year and Date
  2014-04-03 – 2014-04-05
- Data Source
  KAKENHI-PROJECT-25670568
[Presentation] β細胞におけるグルコース作用：代謝に依存しない作用の検討
- Author(s)
  中川祐子、長澤雅裕、最上秀夫、小島至
- Organizer
  第５５回日本糖尿病学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659466

1. SHIBATA Hiroshi (20235584)

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Kojima Itaru 小島 至

KOJIMA Itaru 小島 至

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Idenitification of the endogenous ligand for the sweet taste receptor expressed in pancreatic beta-cellsPrincipal Investigator

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Regulation of the endocrine system by the sweet taste receptorPrincipal Investigator

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Sweet Tase Receptor Expressed in Pancreatic β-cells: PotentialTherapeutic TargetPrincipal Investigator

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膵β細胞に発現する甘味受容体:その機能と臨床的意義の解明Principal Investigator

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新しいインスリンの標的分子TRPV2:インスリン作動性チャネルの生理的意義の確立Principal Investigator

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Kojima Itaru 小島至

KOJIMA Itaru 小島至