SHIBATA Hiroshi 柴田宏

Researcher Number	20235584
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2018 – 2019: 群馬大学, 生体調節研究所, 准教授 2007 – 2016: Gunma University, Institute for Molecular and Cellular Regulation, Associate Professor 2004 – 2006: 群馬大学, 生体調節研究所, 助教授 1995 – 2002: Associate Professor, ibid., 生体調節研究所, 助教授 1994: Gunma University, Institute for Molecular and Cellular Regulation, Department of Cell Biology, lecturer, 生体調節研究所, 講師 … More
Review Section/Research Field	Principal Investigator Metabolomics / 内分泌・代謝学 / Metabolomics / Biological Sciences / Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator 内分泌・代謝学 / Gastroenterology / Digestive surgery / Digestive surgery
Keywords	Principal Investigator インスリン / Rab4 / グルコーストランスポーター / GLUT4 / insulin / glucose transporter / 脂肪細胞 / GTP結合蛋白 / SNARE / Ubc9 … More Except Principal Investigator アクチビンA / インスリン / 増殖因子 / 分化誘導 / activin A / オートクリン因子 / フォリスタチン / カルシウム / 細胞増殖 / アクチビン / differentiation / 膵内分泌細胞 / insulin / 血管平滑筋細胞 / GTP結合蛋白 / 脂肪細胞 / TGF-β / TGF-beta / growth / autocrine / growth factor / オートクリン機構 / 分化誘導因子 / pancreatic endocrine cell / 肝再生 / liver regeneration / follistatin / hepatectomy / ベータセルリン / 肝細胞増殖因子 / 膵β細胞 / 肝移植 / 糖尿病 / 増殖抑制 / グルコーストランスポーター / グリコーストランスポーター / イオンチャネル / インヒビン / 活性因子 / 肝細胞 / 下垂体ホルモン / inhibin / パラクリン因子 / パラクリン機構 / 局所因子 / calcium / paracrine / 肝切除 / 肝細胞壊死 / DNA合成 / 肝壊死 / hepatic necrosis / DNA synthesis / 膵B細胞 / beta-cell / betacellulin / hepatocyte growth factor / ペプチド合成 / 90%肝切除 / activin A, / analog of follistatin / 再生 / 幹細胞 / ランゲルハンス島 / β細胞 / 遺伝子 / pancreatic β cells / regeneration / stem cell / diabetes / islet / 有茎分節腸管 / 肝組織片移植 / 膵組織片移植 / 膵島細胞移植 / 体内型補助肝・膵臓 / 膵移植 / 体内型補助肝･膵臓 Less

GLUT4の空間・時間的運命を制御するインスリン・シグナルの解明Principal InvestigatorOngoing
- Principal Investigator
  
  柴田宏
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Gunma University
Development of auxiliary liver and pancreas using a small intestinal segment packed together with liver micro fragments and pancreatic islets.
- Principal Investigator
  
  Kogure Kimitaka
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University
Role of non-canonical T1R3 homomeric sweet receptor in adipogenesis and glucose transportPrincipal Investigator
- Principal Investigator
  
  Shibata Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
Mechanism of insulin-induced GLUT4 down-regulation through retromer inhibitionPrincipal Investigator
- Principal Investigator
  
  SHIBATA Hiroshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
Mechanism of Insulin Sensitivity Regulation by the SUMO conjugating enzyme, Ubc9Principal Investigator
- Principal Investigator
  
  SHIBATA Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
A study of the SUMO-conjugating enzyme Ubc9 as a novel regulatory factor of insulin sensitivityPrincipal Investigator
- Principal Investigator
  
  SHIBATA Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
A novel mechanism of insulin sensitivity regulation by post-translational mechanismsPrincipal Investigator
- Principal Investigator
  
  SHIBATA Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
翻訳後修飾を介したGLUT4蛋白の細胞内トラフィック調節機構の解明Principal Investigator
- Principal Investigator
  
  柴田宏
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
Cell Biological Dissection of GLUT4 Trafficking PathwaysPrincipal Investigator
- Principal Investigator
  
  SHIBATA Hiroshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University, Institute For Molecular and Cellular Regulation
The mechanisms of insulin-regulated exocytosis of the GLUT4-containing vesiclesPrincipal Investigator
- Principal Investigator
  
  SHIBATA Hiroshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University, Institute For Molecular and Cellular Regulation
Development of a cell-free system for study of insulin actionPrincipal Investigator
- Principal Investigator
  
  SHIBATA Hiroshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
Regeneration of Pancreatic β-cells
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University
Study on the mechanism of insulin stimulation of glucose transportPrincipal Investigator
- Principal Investigator
  
  SHIBATA Hiroshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University, Institute For Molecular and Cellular Regulation
Differentiation of Pancreatic Endocrine Cells
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University
A DEVELOPMENT OF THE NEW METHOD WHICH ACCELERATES LIVER REGENERATION BY USING PEPTIDE TECHNOLOGY
- Principal Investigator
  
  KOGURE Kimitaka
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Gunma University School of Medicine
細胞増殖調節・癌化のシグナル伝達とカルシウム透過性イオンチャネル
- Principal Investigator
  
  小島至
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
Recycling of glucose transporter and insulin actionPrincipal Investigator
- Principal Investigator
  
  SHIBATA Hiroshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University
インスリンの糖取込み促進作用とGTP結合蛋白
- Principal Investigator
  
  小島至
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
Development of New Anti-diabetic Peptide DrugPrincipal Investigator
- Principal Investigator
  
  SHIBATA Hiroshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Institute for Molecular and Cellular Regulation, Gunma University
血管内皮平滑筋連関におけるアクチビンの役割に関する研究
- Principal Investigator
  
  小島至
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
インスリンの糖取込促進作用とGTP結合蛋白
- Principal Investigator
  
  小島至
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
Local Regulation of Endocrine Organ by Members of TGF family
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University
Development of Therapentic Method to Promote Liver Regeneration by Modulating the Activin-Follistatin System
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Gunma University
Study on the mechanism of insulin action on glucose transportPrincipal Investigator
- Principal Investigator
  
  SHIBATA Hiroshi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University Institute For Molecular and Cellular Regulation
内皮血管平滑筋連関におけるアクチビンの役割に関する研究
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gunma University
Studies on the action of activin A
- Principal Investigator
  
  KOJIMA Itaru
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University

[Book] Principles and Practice内分泌・代謝「脂肪細胞が分泌するホルモン(アディポカイン)の作用」(編集:寺内康夫, 鯉淵典之, 後藤英司)2011
- Author(s)
  柴田宏, 小島至
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-20591046
[Book] Principles and Pra ctice内分泌・代謝(編集:寺内康夫,鯉淵典之,後藤英司)(脂肪細胞が分泌するホルモン(アディポカイン)の作用)2010
- Author(s)
  柴田宏,他
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-20591046
[Journal Article] Epigenetic regulation of beige adipocyte fate by histone methylation2019
- Author(s)
  Tanimura K, Suzuki T, Vargas D, Shibata H, Inagaki T
- Journal Title
  
  Endocrine Journal
  
  Volume: 66 Issue: 2 Pages: 115-125
- DOI
  10.1507/endocrj.ej18-0442
  10.1507/endocrj.EJ18-0442
- NAID
  130007605367
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08463
[Journal Article] T1R3 Homomeric Sweet Taste Receptor Regulates Adipogenesis Through Gαs-Mediated Microtubules Disassembly and Rho Activation in 3T3-L1 Cells2017
- Author(s)
  Y. Masubuchi, Y. Nakagawa, J. Medina, M. Nagasawa, I. Kojima, M. M. Rasenick, T. Inagaki, H. Shibata
- Journal Title
  
  Plos one.
  
  Volume: -
- DOI
  10.1371/journal.pone.0176841
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461325, KAKENHI-PROJECT-15K10019, KAKENHI-PROJECT-25291002, KAKENHI-PROJECT-17H03631
[Journal Article] Prolonged insulin stimulation down-regulates GLUT4 through oxidative stress-mediated retromer inhibition by a protein kinase CK2-dependent mechanism in 3T3-L1 adipocytes2014
- Author(s)
  Ma J, Nakagawa Y, Kojima I, Shibata H
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Pages: 133-142
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461325
[Journal Article] Glucose promotes its own metabolism by acting on the cell-surface glucose-sensing receptor T1R32014
- Author(s)
  Nakagawa Y, Ohtsu Y, Nagasawa M, Shibata H, Kojima I
- Journal Title
  
  Endocr J
  
  Volume: 61 Pages: 119-131
- NAID
  130004718269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461325
[Journal Article] Prolonged insulin stimulation down-regulates GLUT4 through oxidative stress-mediated retromer inhibition by a protein kinase CK2-dependent mechanism in 3T3-L1 adipocytes2014
- Author(s)
  Ma J, Nakagawa Y, Kojima I, Shibata H
- Journal Title
  
  J Biol Chem
  
  Volume: Vol.289 Pages: 133-142
- DOI
  10.1074/jbc.m113.533240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591295
[Journal Article] Glucose promotes its own metabolism by acting on the cell-surface glucose-sensing receptor T1R32014
- Author(s)
  Nakagawa Y, Ohtsu Y, Nagasawa M, Shibata H, Kojima I
- Journal Title
  
  Endocr J
  
  Volume: Vol.61 Pages: 119-131
- NAID
  130004718269
- URL
  https://www.jstage.jst.go.jp/article/endocrj/61/2/61_EJ13-0431/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591295
[Journal Article] Miglitol prevents diet-induced obesity by stimulating brown adipose tissue and energy expenditure independent of preventing the digestion of carbohydrates2013
- Author(s)
  Sasaki T, Shimpuku M, Kitazumi T, Hiraga H, Nakagawa Y, Shibata H, Okamatsu-Ogura Y, Kikuchi O, Kim HJ, Fujita Y, Maruyama J, Susanti VY, Yokota-Hashimoto H, Kobayashi M, Saito M, Kitamura T
- Journal Title
  
  Endocr J
  
  Volume: Vol.60 Pages: 1117-1129
- NAID
  130004770394
- URL
  https://www.jstage.jst.go.jp/article/endocrj/60/10/60_EJ13-0333/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591295
[Journal Article] ovel regulatory function of sweet taste-sensing receptor in adipogenic differentiation of 3T3-L1 cells.2013
- Author(s)
  Masubuchi Y, Nakagawa Y, Ma J, Sasaki T, Kitamura T, Yamamoto Y, Kurose H, Kojima I, Shibata H
- Journal Title
  
  PLoS ONE
  
  Volume: Vol.8
- DOI
  10.1371/journal.pone.0054500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591295, KAKENHI-PROJECT-23659466
[Journal Article] Microtubule Disruption with BAPTA and Dimethyl BAPTA by a Calcium Chelation-Independent Mechanism in 3T3-L1 Adipocytes2009
- Author(s)
  Furuta A., Tanaka M., Omata W., Nagasawa M., Kojima I., Shibata H.
- Journal Title
  
  Endocrine J. Vol.56, No.2
  
  Pages: 235-243
- NAID
  10026913018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591046
[Journal Article] Dictyostelium differentiation-inducing factor-1 (DIF-1) induces GLUT1 translocation and promotes glucose uptake in mammalian cells2007
- Author(s)
  Omata, W., Shibata, H., Nagasawa, M., Kojima, I., Kikuchi, H., Oshima, Y., Hosaka, K., Kubohara, Y.
- Journal Title
  
  FEBS J. 274
  
  Pages: 3392-3404
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590974
[Journal Article] The SUMO conjugating enzyme Ubc9 is a regulator of GLUT4 turnover and targeting to the insulin-responsive storage compartment in 3T3-L1 adipocytes2007
- Author(s)
  Liu, L. B., Omata, W., Kojima, I., Shibata, H.
- Journal Title
  
  Diabetes 56
  
  Pages: 1977-1985
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590974
[Journal Article] Rab4 GTP/GDP modulates amiloride-sensitive sodium channel (ENaC) function in colonic epithelia2006
- Author(s)
  Saxena, S. K., Singh, M., Shibata, H., Kaur, S., George, C.
- Journal Title
  
  Biochem. Biophys. Res. Commun 340
  
  Pages: 726-33
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590974
[Journal Article] 小胞輸送とインスリン感受性発現調節2005
- Author(s)
  柴田宏
- Journal Title
  
  臨床病理 53・10
  
  Pages: 942-942
- NAID
  10016926022
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590867
[Journal Article] Regulation of Insulin Sensitivity by Subcellular GLUT4 Targeting2005
- Author(s)
  Shibata, H.
- Journal Title
  
  Rinsho Byori 53-10
  
  Pages: 942-942
- NAID
  10016926022
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590867
[Journal Article] 小胞輸送とインスリン感受性発現調節2005
- Author(s)
  柴田宏
- Journal Title
  
  臨床病理 53・10
  
  Pages: 942-942
- NAID
  10016926022
- Data Source
  KAKENHI-PROJECT-16590867
[Presentation] 脂肪細胞分化制御因子としての鉄イオンの役割とその細胞内動態2020
- Author(s)
  柴田宏，鈴木智大，谷岡安紀子，谷村恭子，Diana Vargas，Silvia Bolzani，林真友子，板橋英之，稲垣毅
- Organizer
  第34回日本糖尿病・肥満動物学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K08463
[Presentation] Role of iron in adipogenic differentiation of 3T3-L1 cells2018
- Author(s)
  Shibata H, Suzuki T, Tanimura K, Vargas D, Hirayama T, Nagasaki H, Inagaki T
- Organizer
  The 4th IMCR Symposium on Endocrine and Metabolism- At the Cutting Edge of Metabolic Regulation Research
- Data Source
  KAKENHI-PROJECT-18K08463
[Presentation] マクロファージに発現するT1R3ホモマー甘味受容体の機能2017
- Author(s)
  李龍飛，ヨハン・メディナ，長澤雅裕，稲垣毅，柴田宏
- Organizer
  第60回日本糖尿病学会年次学術集会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2017-05-18
- Data Source
  KAKENHI-PROJECT-26461325
[Presentation] Gs共役T1R3ホモマー甘味受容体による脱アセチル化酵素SIRT2活性化と脂肪分化抑制2015
- Author(s)
  増渕洋祐，小島至，柴田宏
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ（山口県・下関市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26461325
[Presentation] Two Divergent Signals from the Gs-Coupled T1R3 Homomeric Sweet Taste Receptor Converge at FoxO1 to Inhibit Adipogenesis in 3T3-L1 Cells2015
- Author(s)
  Yosuke Masubuchi, Itaru Kojima, Hiroshi Shibata
- Organizer
  American Diabetes Association 75th Scientific Sessions
- Place of Presentation
  ボストンコンベンション・エグジビションセンター（アメリカ合衆国・マサチューセッツ州・ボストン市）
- Year and Date
  2015-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461325
[Presentation] Sweet taste receptor regulates adipogenesis through Gs-mediated microtubule disassembly and Rho activation in 3T3-L1 cells2013
- Author(s)
  Masubuchi Y, Nakagawa Y, Ma J, Nagasawa M, Kojima I, Shibata H
- Organizer
  73rd Scientific Session of American Diabetes Association
- Place of Presentation
  マコーミックプレイス・コンベンションセンター(米国シカゴ市)
- Data Source
  KAKENHI-PROJECT-23591295
[Presentation] Sweet Taste Receptor Regulates Adipogenesis Through Gs-Mediated Microtubule Disassembly and Rho Activation in 3T3-L1 Cells2013
- Author(s)
  Masubuchi Y, Nakagawa Y, Ma J, Nagasawa M, Kojima I, Shibata H
- Organizer
  73rd Scientific Sessions of American Diabetes Association
- Place of Presentation
  マコーミックプレイス・コンベンションセンター（米国シカゴ市）
- Data Source
  KAKENHI-PROJECT-23591295
[Presentation] 甘味刺激によるGs活性化は微小管脱重合とRho活性化を介して脂肪分化を抑制する2013
- Author(s)
  増渕洋祐,中川祐子,馬金輝,長澤雅裕,小島至,柴田宏
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-23591295
[Presentation] 新規インスリン・シグナル分子PC-PLCによるNox4活性化機構2012
- Author(s)
  馬金輝，小島至，柴田宏
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-23591295
[Presentation] A Novel Regulatory Function of Sweet Taste-Sensing Receptor in Adipogenic Differentiation of 3T3-L1 Cells2012
- Author(s)
  Masubuchi, Y., Nakagawa, Y., Ma, J., Kojima, I., Shibata, H.
- Organizer
  American Diabetes Association 72nd Scientific Sessions
- Place of Presentation
  ペンシルベニア・コンベンションセンター（米国フィラデルフィア市）
- Data Source
  KAKENHI-PROJECT-23591295
[Presentation] 新規インスリン・シグナル分子PC-PLCによるNox4活性化機構2012
- Author(s)
  馬金輝,小島至,柴田宏
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Data Source
  KAKENHI-PROJECT-23591295
[Presentation] 甘味受容体による脂肪細胞分化抑制のシグナル機構2012
- Author(s)
  増渕洋祐,中川祐子,馬金輝,小島至,柴田宏
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Data Source
  KAKENHI-PROJECT-23591295
[Presentation] A novel regulatory function of sweet taste-sensing receptor in adipogenic differentiation of 3T3-L1 cells2012
- Author(s)
  Masubuchi Y, Nakagawa Y, Ma J, Kojima I, Shibata H
- Organizer
  72nd Scientific Session of American Diabetes Association
- Place of Presentation
  ペンシルベニア・コンベンションセンター(米国フィラデルフィア市)
- Data Source
  KAKENHI-PROJECT-23591295
[Presentation] 脂肪細胞における活性酸素産生と GLUT4 分解を惹起するインスリン・シグナル機構2011
- Author(s)
  柴田宏，馬金輝，小島至
- Organizer
  生理学研究所研究会「超階層シグナル伝達研究の新展開」
- Place of Presentation
  岡崎市
- Data Source
  KAKENHI-PROJECT-23591295
[Presentation] ホスファチジルコリン特異的PLCは脂肪細胞における活性酸素産生とGLUT4分解のインスリン・シグナル分子として機能する2011
- Author(s)
  馬金輝、小島至、柴田宏
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23591295
[Presentation] 脂肪細胞における甘味受容体の発現と機能2011
- Author(s)
  増渕洋祐,中川祐子,馬金輝,小島至,柴田宏
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23591295
[Presentation] ホスファチジルコリン特異的PLCは脂肪細胞における活性酸素産生とGLUT4分解のインスリン・シグナルとして機能する2011
- Author(s)
  馬金輝,小島至,柴田宏
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23591295
[Presentation] インスリンによる活性酸素産生亢進を介したレトロマー機能の阻害とGLUT4分解促進2010
- Author(s)
  馬金輝,長澤雅裕,中川祐子,小島至,柴田宏
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山全日空ホテル(岡山市)
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-20591046
[Presentation] インスリンによるレトロマー機能制御におけるCK2の役割2010
- Author(s)
  柴田宏,馬金輝,中川裕子,小島至
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山市デジタルミュージアム(岡山市)
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-20591046
[Presentation] インスリンによるGLUT4分解促進作用におけるレトロマー複合体の役割と調節2009
- Author(s)
  柴田宏,馬金輝,中川裕子,小島至
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  リーガロイヤルホテル大阪(大阪府)
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20591046
[Presentation] The Role for the Retromer Complex in GLUT4 Trafficking and Degradation in Adipocytes.2009
- Author(s)
  Shibata, H., et al
- Organizer
  第69回米国糖尿病学会学術集会
- Place of Presentation
  モリアル・コンベンションセンター(ニューオリンズ市)
- Year and Date
  2009-06-06
- Data Source
  KAKENHI-PROJECT-20591046
[Presentation] The Role for the Retromer Complex in GLUT4 Trafficking and Degradation in Adipocytes2009
- Author(s)
  Shibata H., Ma J., Nakagawa Y., Kodera T., Yoshida R., Kojima I.
- Organizer
  第69回米国糖尿病学会学術集会
- Place of Presentation
  メモリアル・コンベンションセンター(ニューオリンズ市,アメリカ合衆国)
- Year and Date
  2009-06-06
- Data Source
  KAKENHI-PROJECT-20591046
[Presentation] インスリンによるレトロマー複合体の機能制御とGLUT4分解促進機構-酸化ストレスと細胞内トラフィックの接点-2009
- Author(s)
  柴田宏
- Organizer
  生体調節研究所シンポジウム「代謝疾患研究の最前線」
- Place of Presentation
  群馬大学生体調節研究所(前橋市)
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-20591046
[Presentation] インスリンによるCLUT4分解促進作用におけるレトロマー複合体の役割と調節2009
- Author(s)
  柴田宏, 他3名
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  リーガロイヤルホテル大阪(大阪府)
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20591046
[Presentation] インスリンによるGLUT4ダウンレギュレーションにおけるプロテインキナーゼCK2の関与2008
- Author(s)
  柴田宏,小俣和香,長澤雅裕,中川祐子,小島至
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京国際フォーラム,東京都
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-20591046
[Presentation] インスリンによるGLUT4ダウンレギュレーションにおけるプロテインキナーゼCK2の関与2008
- Author(s)
  柴田宏,他4名
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-20591046
[Presentation] The role of ubiquitination in the insulin-induced GLUT4 degradation2007
- Author(s)
  Shibata, H., et. al.
- Organizer
  The 50th Annual Meeting of the Japan Diabetes Society
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590974
[Presentation] インスリンによるGLUT4分解促進作用におけるユビキチン化の関与2007
- Author(s)
  柴田宏, 他3名
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台市
- Year and Date
  2007-05-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590974
[Presentation] Gs共役型T1R3ホモマー甘味受容体による微小管脱重合とRho活性化を介したインスリン依存性グルコース輸送の抑制
- Author(s)
  増渕洋祐，中川祐子，馬金輝，長澤雅裕，小島至，柴田宏
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26461325

1. KOJIMA Itaru (60143492)

# of Collaborated Projects: 14 results

# of Collaborated Products: 0 results
2. KOGURE Kimitaka (80143220)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. MASHIMA Hirosato (10261869)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 田中滋康 (90146233)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KANZAKI Makoto (10272262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Kogure Kimitaka (20125850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 張有青 (10302499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAGASAWA Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. INAGAKI Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIBATA Hiroshi 柴田 宏

Research Projects

Research Products

Co-Researchers

GLUT4の空間・時間的運命を制御するインスリン・シグナルの解明Principal InvestigatorOngoing

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Principal Investigator

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Role of non-canonical T1R3 homomeric sweet receptor in adipogenesis and glucose transportPrincipal Investigator

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Mechanism of insulin-induced GLUT4 down-regulation through retromer inhibitionPrincipal Investigator

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Mechanism of Insulin Sensitivity Regulation by the SUMO conjugating enzyme, Ubc9Principal Investigator

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A study of the SUMO-conjugating enzyme Ubc9 as a novel regulatory factor of insulin sensitivityPrincipal Investigator

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A novel mechanism of insulin sensitivity regulation by post-translational mechanismsPrincipal Investigator

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翻訳後修飾を介したGLUT4蛋白の細胞内トラフィック調節機構の解明Principal Investigator

Principal Investigator

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Cell Biological Dissection of GLUT4 Trafficking PathwaysPrincipal Investigator

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The mechanisms of insulin-regulated exocytosis of the GLUT4-containing vesiclesPrincipal Investigator

Principal Investigator

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Development of a cell-free system for study of insulin actionPrincipal Investigator

Principal Investigator

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Study on the mechanism of insulin stimulation of glucose transportPrincipal Investigator

Principal Investigator

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SHIBATA Hiroshi 柴田宏