• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Akao Yukihiro  赤尾 幸博

ORCIDConnect your ORCID iD *help
… Alternative Names

AKAO Yukihiro  赤尾 幸博

赤尾 幸博  アカオ ユキヒロ

Less
Researcher Number 00222505
Other IDs
Affiliation (Current) 2022: 岐阜大学, 大学院連合創薬医療情報研究科, 特任教授
Affiliation (based on the past Project Information) *help 2018 – 2021: 岐阜大学, 大学院連合創薬医療情報研究科, 特任教授
2015 – 2017: 岐阜大学, 大学院連合創薬医療情報研究科, 教授
2014 – 2015: 岐阜大学, その他の研究科, 教授
2009 – 2015: Gifu University, 連合創薬医療情報研究科, 教授
2014: 岐阜大学, 連合創薬医薬医療情報研究科, 教授 … More
2013: 岐阜大学院, 連合創薬, 教授
2012 – 2013: 岐阜大学, 大学院連合創薬医療情報研究科, 教授
2010: 岐阜大学, 大学院・連合創薬医療情報研究科, 教授
2008: Gifu International Institute of Biotechnology, 腫瘍医学研究部, 部長
2005: GIFU INTERNATIONAL INSTITUTE OF BIOTECHNOL, CHIEF, 部長
2005: (財)岐阜県国際バイオ研究所, 遺伝子診断研究部, 部長
2004: 財団法人岐阜県国際バイオ研究所, 部長
2004: 財団法人岐阜県国際バイオ研究所, 遺伝子診断部, 部長
2003: (財)岐阜県国際バイオ研究所, 遺伝子診断部, 部長
2002 – 2003: (財)岐阜県国際バイオ研究所, 部長
2002: (財)岐阜国際バイオ研究所, 部長
2000 – 2001: (財)応用生化学研究所, 研究部長
1999: 財団法人 応用生化学研究所, 部長
1998: Institute of Appleed Bilchemistry, Chief Researcher, 研究部長
1997 – 1998: (財)応用生化学研究所, 主任研究員
1994 – 1995: 大阪医科大学, 医学部, 助教授
1994: 大阪大学, 医学部, 助教授
1992: 大阪医科大学, 第一解剖学教室, 助教授
1991: 愛知県がんセンター研究所, 化学療法部, 主任研究員 Less
Review Section/Research Field
Principal Investigator
Experimental pathology / Experimental pathology / Human genetics / Hematology / Pediatrics
Except Principal Investigator
Digestive surgery / Pathological medical chemistry / Biological pharmacy / Experimental pathology / Clinical veterinary science … More / Hematology / Obstetrics and gynecology / Biological Sciences / Pathological medical chemistry / General surgery / Applied molecular and cellular biology / Applied health science / Basic Section 55020:Digestive surgery-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related Less
Keywords
Principal Investigator
染色体転座 / 造血器腫瘍 / MLL遺伝子 / アポトーシス / 11q23 / 翻訳開始 / RNAヘリカーゼ / 大腸腫瘍 / Leukemia / MLL … More / 乳児白血病 / キメラ蛋白 / rck / p54 / DEADボックス蛋白 / RNA構造 / 遺伝子発現 / 発癌 / C型肝炎ウイルス / 肝癌 / c-myc mRNA / C型肝炎 / マイクロRNA / がん / microRNA-143、-145 / c-myc / 消化管腫瘍 / 癌 / 翻訳制御 / がん抑制遺伝子 / ヌクレアーゼ耐性 / 化学修飾 / 増殖抑制 / 腫瘍縮小効果 / がん抑制マイクロRNA / ERK5 / RNA創薬 / 薬剤搬送システム / 分泌膜小胞 / 核酸治療 / がん細胞 / 薬物搬送システム(DDS) / CD81 / RNA医薬搬送システム / Drug Delivery System / 染色体11q23 / RCK遺伝子 / 染色体第11番q23 / bcl-2蛋白 / Chromosome 11q23 / Chromosome translocation / Malignant lymhoma / RCK / アンチセンスDNA / t(11;19)転座 / PCR法 / 染色体11番q23 / アンチセンスオリゴヌクレオチド / ヒ素 / imfantile leukemia / chromosome translocation / MLLgene / antisense DNA / t(11;19) translocation / PCR / 薬剤耐性 / MILL遺伝子 / 細胞増殖抑制 / 亜ヒ酸 / INFANTILELEUKEMIA / CHROMOSOMAL TRANSLOCATION / MLLGENE / APOPTOSIS / DRUG RESISTENCE / CHIMERIC PROTEIN / mRNA分解 / 細胞増殖 / DEAD-box RNAヘリカーゼ / 細胞周期 / 発癌機構 / 転座関連遺伝子 / RNA分解 / DEAD-bex RNAヘリカーゼ / eIF4E / DEAD-box / translation initiation / degradation of mRNAs / cell proliferation / DAED-box RNA helicase / cell cycle / carcinogenesis / genes associated with chromosome translocation … More
Except Principal Investigator
microRNA / アポトーシス / ホスホリパーゼD / エクソソーム / シグナル伝達 / Akt / PHOSPHOLIPASE D / PHOSPHATIDYLINOSITOL 3-KINASE / AKT / exosome / 癌 / メラノーマ / マイクロRNA / miRNA / bcl-2 / ER / PgR / PI3キナーゼ / H_2O_2 / ERK / 分化 / SURVAIVAL / セラミド / APOPTOSIS / PTBP1 / Warburg効果 / 乳癌 / Exosome / 細胞外小胞 / 転座関連遺伝子 / 造血器腫瘍 / t(11;4)転座 / RCK遺伝子 / t(4;11)転座 / t(11;19)転座 / PRADI遺伝子 / 11q13(bclー1)遺伝子 / 白血病 / リンパ腫 / 染色体転座 / Translocation / がん遺伝子 / RhoGEF / Rho / チロシンリン酸化 / キナーゼ / リン酸化 / 三量体G蛋白質 / アクチン / プロモーター / DDX6 / P-body / イヌ口腔内メラノーマ / FLT3阻害剤 / 分子標的剤 / STAT3/5阻害剤 / pyruvinium pamoate / 中鎖脂肪酸誘導体 / トランスレーショナルリサーチ / 子宮内膜 / 月経 / bcl-2蛋白 / IL-7存在性B細胞株 / TUNEL法 / 免疫電顕 / ウエスタン・ブロット / ホルモンリセプター / Apoptosis / Endometrium / Menstruation / 抗アポトーシス作用 / スフィンゴシン1-リン酸 / 癌化 / P38MAPK / 遺伝子導入 / 細胞機能解析 / 情報変換酵素 / 情報伝達 / 分泌応答 / 増殖 / 老化 / SPHINGOSINE 1-PHOSPHATE / スフィンゴミエリン / スフィンゴミエリン代謝 / SPHINGOMYELIN / CERAMIDE / ホスホリバーゼD / 生存シグナル / ホスファチジルイノシトール3キナーゼ / スフィンゴシンキナーゼ / Pyk2 / 酸化ストレス / 脂質 / Aktキナーゼ / Pyk2キナーゼ / 生存シグナリング / Signal transduction / Oxidative stress / Lipids / Phospholipase D / Warburg 効果 / RNA helicase / MYC / microvesicle / VEGF-C / マウス乳癌細胞 / リンパ行性転移 / リンパ管新生 / オートクライン / microvesicles / 乳癌のリンパ行性転移 / 転移性の差異 / 低酸素 / exosomes / 乳癌細胞 / リンパ管形成 / matureVEGF-C / precursorVEGF-C / lymphangiogenesis / metastasis / microRNA-205 / CD9 / TGF-β / 胃癌 / 胃液 / Extracellular Vesicles / Microvesicles / 微小環境 / EVs / マイクロベジクル / 超遠心法 / 医療・福祉 / 4型胃癌 / バイオマーカー / 膵癌 / ワールブルク効果 / スプライサー / ワールブルグ効果 / ワーバーグ効果 / PTBP1遺伝子 / 骨細胞 / 骨芽細胞 / メカニカルストレス / 破骨細胞 / 膜微小胞 / 骨代謝 / 核酸医薬 / 大腸癌 / ドラッグデリバリー / microRNA-143 / microRNA-145 / ペプチドキャリア / ドラッグデリバリーシステム / miR-143 / miR-145 / 化学修飾 / 消化器癌 / 医工薬連携 / micoRNA / GPCR / PKA / CD81 / small GTPase / Gタンパク質 Less
  • Research Projects

    (26 results)
  • Research Products

    (96 results)
  • Co-Researchers

    (46 People)
  •  Mechanism of Exosome Production by Heterotrimeric G Protein Signaling

    • Principal Investigator
      Ueda Hiroshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Gifu University
  •  Realization of microRNA drug discovery, overcoming intractable cancer through medicine-engineering-pharmacy collaboration

    • Principal Investigator
      Uchiyama Kazuhisa
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Osaka Medical College
  •  Investigation of extracellular vesicles as novel biomarker in 4 type gastric cancer patients

    • Principal Investigator
      Lee Sang-Woong
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka Medical College
  •  The elucidation of biliary and pancreatic tumor's pathobiology through the functional analysis of novel Warburg effect-associated gene PTBP1

    • Principal Investigator
      Asakuma Mitsuhiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka Medical College
  •  Identification of the Warburg effect-associated microRNAs and those targeting genes and clinical application of those

    • Principal Investigator
      UCHIYAMA Kazuhisa
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka Medical College
  •  Development of exosome including osteogenesis-related microRNA

    • Principal Investigator
      Itoh Tomohiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied health science
    • Research Institution
      Mie University
      Kinki University
  •  The role of exosome derived melanoma cells in tumor immunity

    • Principal Investigator
      Noguchi Shunsuke
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied molecular and cellular biology
    • Research Institution
      Yamaguchi University
  •  Translational research toward drug discovery of leukemia

    • Principal Investigator
      NAOE Tomoki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      National Hospital Organization Nagoya Medical Center
  •  Mouse mammary carcinoma cell lines release microvesicles containing precurcer VEGF-C

    • Principal Investigator
      Ito Yuko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Osaka Medical College
  •  Therapeutic application of microRNA for canine oral malignant melanoma.

    • Principal Investigator
      MORI Takashi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Clinical veterinary science
    • Research Institution
      Gifu University
  •  Trial of RNA medicine using secretory membrane vesiclesPrincipal Investigator

    • Principal Investigator
      AKAO Yukihiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Human genetics
    • Research Institution
      Gifu University
  •  The physiological roles of the phosphorylation of heterotrimeric G protein signal-dependent RhoGEFs

    • Principal Investigator
      UEDA Hiroshi
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Gifu University
  •  Molecular mechanism of miR-143/145 down-regulation in cancer and disease

    • Principal Investigator
      IIO Akio
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Institute for Developmental Research, Aichi Human Service Center
      Gifu International Institute of Biotechnology
  •  Role of miR-143 and -145 in carcinogenesis of colon cancerPrincipal Investigator

    • Principal Investigator
      AKAO Yukihiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Gifu International Institute of Biotechnology
  •  REGULATORY MECHANISM BY PHOSPHOLIPASE D IN OXIDANT-STRESS INDUCED SURVIVAL SIGNALING

    • Principal Investigator
      NOZAWA Yoshinori
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      GIFU INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY
  •  Human DEAD-box/RNA helicase rck/p54 contributes to maintenance of cell growth by affecting cell cycle in cultured cellsPrincipal Investigator

    • Principal Investigator
      AKAO Yukihiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Gifu International Institute of Biotechnology
  •  RNAヘリカーゼと癌関連遺伝子の発現に関する機能解析と分子イメージングPrincipal Investigator

    • Principal Investigator
      赤尾 幸博
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Gifu International Institute of Biotechnology
  •  CROSS-TALK OF MEMBRANE LIPID SIGNALING IN CELL DEATH AND SURVIVAL

    • Principal Investigator
      NOZAWA Yoshinori
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      GIFU INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY
  •  MECHNISM OF APOPTOSIS INDUCED BY MEMBRANE LIPID SYGNALING

    • Principal Investigator
      NOZAWA Yoshinori
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      INSTITUTE OF APPLIED BIOCHEMISTRY
  •  THE RELATION OF VARIANT MLL GENE TO CELL DEATH AND UNRESPONSIVENESS TO CHEMOTHERAPY IN INFANTILE LEUKEKEMIA WITH 11q23 TRANSLOCATIONPrincipal Investigator

    • Principal Investigator
      AKAO Yukihiro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      INSTITUTE OF APPLIED BIOCHEMISTRY
  •  Functional analysis of the new signal transduction enzyme PLD by the molecular genetic technique

    • Principal Investigator
      NOZAWA Yoshinori
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (B)
    • Review Section
      Biological Sciences
    • Research Institution
      INSTITUTE OF APPLIED BIOCHEMISTRY
      Gifu University
  •  Molecular diagnosis and theray of infantile acute leukemia carrying 11q23 translocationsPrincipal Investigator

    • Principal Investigator
      AKAO Yukihiro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Institute of Applied Biochemistry
  •  The role of Chromosome translocation-related genes on tumorigenecity in hematological malignanciePrincipal Investigator

    • Principal Investigator
      AKAO Yukihiro
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Osaka Medical College
  •  Apoptosis in female genital organs-the relation between bcl-2 protein and hormone receptor

    • Principal Investigator
      OTSUKI Yoshinori
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka Medical College
  •  造血器腫瘍の新しい第11番染色体転座関連遺伝子の単離とその診断と予後判定への応用

    • Principal Investigator
      瀬戸 加大
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  造血器腫瘍の診断と予後判定に有用な新しい転座関連遺伝子

    • Principal Investigator
      上田 龍三
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2011 2010 2009 2008 2006 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Specific inhibition of oncogenic RAS using cell-permeable RAS-binding domains2021

    • Author(s)
      Nomura, T.K., Heishima, K., Sugito, N., Sugawara, R., Ueda, H., Akao, Y. and Honda, R.
    • Journal Title

      Cell Chemical Biology

      Volume: -

    • DOI

      10.1016/j.chembiol.2021.04.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07043, KAKENHI-PROJECT-19K16828
  • [Journal Article] Petasin potently inhibits mitochondrial complex I-based metabolism that supports tumor growth and metastasis.2021

    • Author(s)
      Heishima K, Sugito N, Soga T, Nishikawa M, Ito Y, Honda R, Kuranaga Y, Sakai H, Ito R, Nakagawa T, Ueda H, Akao Y
    • Journal Title

      J Clin Invest

      Volume: 131

    • DOI

      10.1172/jci139933

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07043
  • [Journal Article] Analysis of Extracellular Vesicles in Gastric Juice from Gastric Cancer Patients2019

    • Author(s)
      Kagota Shuji、Taniguchi Kohei、Lee Sang-Woong、Ito Yuko、Kuranaga Yuki、Hashiguchi Yasuyuki、Inomata Yosuke、Imai Yoshiro、Tanaka Ryo、Tashiro Keitaro、Kawai Masaru、Akao Yukihiro、Uchiyama Kazuhisa
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Pages: 953-953

    • DOI

      10.3390/ijms20040953

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10521, KAKENHI-PROJECT-16K10482, KAKENHI-PROJECT-17K10680
  • [Journal Article] α-Aminoisobutyric Acid-Containing Amphipathic Helical Peptide-Cyclic RGD Conjugation as a Potential Drug Delivery System for MicroRNA Replacement Therapy in Vitro2019

    • Author(s)
      Taniguchi Kohei、Wada Shun-ichi、Ito Yuko、Hayashi Junsuke、Inomata Yosuke、Lee Sang-Woong、Tanaka Tomohito、Komura Kazumasa、Akao Yukihiro、Urata Hidehito、Uchiyama Kazuhisa
    • Journal Title

      Molecular Pharmaceutics

      Volume: 16 Pages: 4542-4550

    • DOI

      10.1021/acs.molpharmaceut.9b00680

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08660, KAKENHI-PROJECT-19K05702
  • [Journal Article] The interaction between PLEKHG2 and ABL1 suppresses cell growth via the NF-κB signaling pathway in HEK293 cells.2019

    • Author(s)
      Nishikawa Masashi、Nakano Shun、Nakao Hiromu、Sato Katsuya、Sugiyama Tsuyoshi、Akao Yukihiro、Nagaoka Hitoshi、Yamakawa Hisashi、Nagase Takahiro、Ueda Hiroshi
    • Journal Title

      Cell Signal.

      Volume: 61 Pages: 93-107

    • DOI

      10.1016/j.cellsig.2019.04.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08241, KAKENHI-PROJECT-18K15045, KAKENHI-PROJECT-18J13111, KAKENHI-PROJECT-19K07043
  • [Journal Article] Organ-Specific MicroRNAs (MIR122, 137, and 206) Contribute to Tissue Characteristics and Carcinogenesis by Regulating Pyruvate Kinase M1/2 (PKM) Expression.2018

    • Author(s)
      Taniguchi K, Sugito N, Shinohara H, Kuranaga Y, Inomata Y, Komura K, Uchiyama K, Akao Y.
    • Journal Title

      Int J Mol Sci.

      Volume: 19(5) Pages: 1276-1276

    • DOI

      10.3390/ijms19051276

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H07344, KAKENHI-PROJECT-15K10120, KAKENHI-PROJECT-18K15273
  • [Journal Article] Oncogene RNA helicase DDX6 promotes the process of c-Myc expression in gastric cancer cells.2018

    • Author(s)
      Taniguchi K, Iwatsuki A, Sugito N, Shinohara H, Kuranaga Y, Oshikawa Y, Tajirika T, Futamura M, Yoshida K, Uchiyama K, Akao Y.
    • Journal Title

      Mol Carcinog.

      Volume: 57(5) Pages: 579-589

    • DOI

      10.1002/mc.22781

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H07344, KAKENHI-PROJECT-16J08131, KAKENHI-PROJECT-15K10120
  • [Journal Article] PKM1 is involved in resistance to anti-cancer drugs.2016

    • Author(s)
      Taniguchi K, Sakai M, Sugito N, Kuranaga Y, Kumazaki M, Shinohara H, Ueda H, Futamura M, Yoshida K, Uchiyama K, Akao Y.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 0000 Pages: 0000-0000

    • DOI

      10.1016/j.bbrc.2016.03.074

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K07927, KAKENHI-PROJECT-16J08131, KAKENHI-PROJECT-15K10120
  • [Journal Article] PTBP1-associated microRNA-1 and -133b suppress the Warburg effect in colorectal tumors.2016

    • Author(s)
      Taniguchi K, Sakai M, Sugito N, Kumazaki M, Shinohara H, Yamada N, Nakayama T, Ueda H, Nakagawa Y, Ito Y, Futamura M, Uno B, Otsuki Y, Yoshida K, Uchiyama K, Akao Y.
    • Journal Title

      Oncotarget.

      Volume: 0000 Pages: 0000-0000

    • DOI

      10.18632/oncotarget.8005

    • NAID

      40021358229

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07927, KAKENHI-PROJECT-16J08131, KAKENHI-PROJECT-15K10120, KAKENHI-PROJECT-16K10482
  • [Journal Article] Perturbation of energy metabolism by fatty-acid derivative AIC-47 and imatinib in BCR-ABL-harboring leukemic cells.2016

    • Author(s)
      Shinohara H, Kumazaki M, Minami Y, Ito Y, Sugito N, Kuranaga Y, Taniguchi K, Yamada N, Otsuki Y, Naoe T, Akao Y
    • Journal Title

      Cancer Lett.

      Volume: 371 Pages: 1-11

    • DOI

      10.1016/j.canlet.2015.11.020

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25293218, KAKENHI-PROJECT-16K10482
  • [Journal Article] Positive feedback of DDX6/c-Myc/PTB1 regulated by miR-124 contributes to maintenance of the Warburg effect in colon cancer cells.2015

    • Author(s)
      Taniguchi K, Sugito N, Kumazaki M, Shinohara H, Yamada N, Matsuhashi N, Futamura M, Ito Y, Otsuki Y, Yoshida K, Uchiyama K, Akao Y.
    • Journal Title

      Biochim Biophys Acta

      Volume: 9 Pages: 1971-1980

    • DOI

      10.1016/j.bbadis.2015.06.022

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10120, KAKENHI-PROJECT-25462003
  • [Journal Article] MicroRNA-124 inhibits cancer cell growth through PTB1/PKM1/PKM2 feedback cascade in colorectal cancer.2015

    • Author(s)
      Taniguchi K, Sugito N, Kumazaki M, Shinohara H, Yamada N, Nakagawa Y, Ito Y, Otsuki Y, Uno B, Uchiyama K, Akao Y.
    • Journal Title

      Cancer Lett

      Volume: 1 Pages: 17-27

    • DOI

      10.1016/j.canlet.2015.03.026

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10120, KAKENHI-PROJECT-25462003
  • [Journal Article] Organ-specific PTB1-associated microRNAs determine expression of pyruvate kinase isoforms.2015

    • Author(s)
      Taniguchi K, Ito Y, Sugito N, Kumazaki M, Shinohara H, Yamada N, Nakagawa Y, Sugiyama T, Futamura M, Otsuki Y, Yoshida K, Uchiyama K, Akao Y.
    • Journal Title

      Sci Rep

      Volume: 2 Pages: 8647-8647

    • DOI

      10.1038/srep08647

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10120, KAKENHI-PROJECT-25462003
  • [Journal Article] Anti-cancer fatty-acid derivative induces autophagic cell death through modulation of PKM isoform expression profile mediated by bcr-abl in chronic myeloid leukemia.2015

    • Author(s)
      Shinohara H, Taniguchi K, Kumazaki M, Yamada N, Ito Y, Otsuki Y, Uno B, Hayakawa F, Minami Y, Naoe T, Akao Y.
    • Journal Title

      Cancer Letter

      Volume: 360 Pages: 28-38

    • DOI

      10.1016/j.canlet.2015.01.039

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-25118711, KAKENHI-PROJECT-25293218, KAKENHI-PROJECT-25461412, KAKENHI-PROJECT-25462003
  • [Journal Article] Epigenetic regulation of microRNA-128a expression contributes to the apoptosis-resistance of human T-cell leukaemia Jurkat cells by modulating the expression of Fas-associated protein with death domain (FADD).2014

    • Author(s)
      Yamada N, Noguchi S, Kumazaki M, Shinohara H, Miki K, Naoe T, Akao Y.
    • Journal Title

      Biochim Biophys Acta

      Volume: 1843(3) Pages: 590-602

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293218
  • [Journal Article] Colorectal cancer cell-derived microvesicles containing microRNA-1246 promote angiogenesis by activating Smad 1/5/8 signaling elicited by PML down-regulation in endothelial cells.2014

    • Author(s)
      Yamada N, Tsujimura N, Kumazaki M, Shinohara H, Taniguchi K, Nakagawa Y, Naoe T, Akao Y.
    • Journal Title

      Biochim Biophys Acta.

      Volume: 1839 Pages: 1256-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659157
  • [Journal Article] Role of Intracellular and Extracellular MicroRNA-92a in Colorectal Cancer.2013

    • Author(s)
      Yamada N, Nakagawa Y, Tsujimura N, Kumazaki M, Noguchi S, Mori T, Hirata I, Maruo K, Akao Y.
    • Journal Title

      Transl Oncol.

      Volume: 6(4) Pages: 482-92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659157
  • [Journal Article] MicroRNAs as tumour suppressors in canine and human melanoma cells and as a prognostic factor in canine melanomas.2013

    • Author(s)
      Noguchi S, Mori T, Hoshino Y, Yamada N, Maruo K and Akao Y
    • Journal Title

      Veterinary Comparative Oncology

      Volume: 11 Pages: 113-123

    • DOI

      10.1002/vco.306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24580459
  • [Journal Article] Tumor-suppressive microRNA-145 targets catenin δ-1 to regulate Wnt/β-catenin signaling in human colon cancer cells.2013

    • Author(s)
      Yamada N., Noguchi S., Mor i T., Naoe T., Maruo K. and Akao Y.
    • Journal Title

      Cancer Lett

      Volume: 335 Pages: 332-342

    • DOI

      10.1016/j.canlet.2013.02.060

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J00639, KAKENHI-PROJECT-25293218
  • [Journal Article] DDX6 post-transcriptionally down- regulates miR-143/145 expression through host gene NCR143/145 in cancer cells2013

    • Author(s)
      Iio A, Takagi T, Miki K, Naoe T, Nakayama A, Akao Y.
    • Journal Title

      Biochimica et Biophysica Acta

      Volume: 1829 Pages: 1102-1110

    • DOI

      10.1016/j.bbagrm.2013.07.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590483
  • [Journal Article] Chemically Modified Synthetic microRNA-205 Inhibits the Growth of Melanoma Cells In Vitro and In Vivo2013

    • Author(s)
      Noguchi, S., Iwasaki, J., Kumazaki, M., Mori, T., Maruo, K., Saka,i H., Yamada, N., Shimada, K., Naoe, T., Kitade, Y., and Akao, Y.
    • Journal Title

      Molecular Therapy

      Volume: 21 Pages: 1204-1211

    • DOI

      10.1038/mt.2013.70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23580439, KAKENHI-PROJECT-24390025, KAKENHI-PROJECT-24580459
  • [Journal Article] 3-DECENOIC ACID DERIVATIVES INDUCE AUTOPHAGIC CELL DEATH THROUGH TH EDOWN-REGULATION OF E2F12013

    • Author(s)
      SHINOHARA H.1,2, NOGUCHI S.2, KUMAZAKI M.2,3, YAMADA N.2, ITO T.1, OYAMA M., ITO Y., OTSUKI Y.,NAITO S., IINUMA M. AND AKAO Y.
    • Journal Title

      Journal of Toxicology Research

      Volume: 3 Pages: 29-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462003
  • [Journal Article] Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells.2011

    • Author(s)
      Akao Y, Noguchi S, Iio A, Kojima K, Takagi T, Naoe T.
    • Journal Title

      Cancer Lett. 28,300(2)

      Pages: 197-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells2011

    • Author(s)
      Akao Y, Noguchi S, Iio A, Kojima K, Takagi T, Naoe T
    • Journal Title

      Cancer Lett.

      Volume: 300 Pages: 197-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] MicroRNA-208 modulates BMP-2-stimulated mouse Pre-osteoblast differentiation by directly targeting V-ets erythroblastosis virus E26 oncogene homolog 1.2010

    • Author(s)
      Itoh T, Takeda S, Akao Y.
    • Journal Title

      JBiol Chem. 285

      Pages: 27745-27752

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] Role of anti-oncomirs miR-143 and-145 in human colorectal tumors2010

    • Author(s)
      Akao Y, Nakagawa Y, et al.
    • Journal Title

      Cancer Gene Therapy 10

      Pages: 1-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] Role of anti-oncomirs miR-143 and-145 in human colorectal tumors2010

    • Author(s)
      Akao Y Nakagawa Y, Hirata I, Iio A, Ito T, Kojima K, Nakashima R, Kitade Y, Naoe T.
    • Journal Title

      Cancer Gene Ther 17

      Pages: 398-408

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] Identification of non-coding RNAs embracing microRNA-143/145 cluster.2010

    • Author(s)
      Iio A, Nakagawa Y, Hirata I, Naoe T, Akao Y.
    • Journal Title

      Mol Cancer

      Volume: 9 Pages: 136-141

    • NAID

      120006341933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] MicroRNAs and their therapeutic potential for human diseases : microR NAs, miR-143 and -145, function as anti-oncomirs and the application of chemically modified miR-143 as an anti-cancer drug2010

    • Author(s)
      Kitade Y, Akao Y
    • Journal Title

      J Pharmacol Sci.

      Volume: 114 Pages: 276-280

    • NAID

      10029890344

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] Identification of non-coding RNAs embracing microRNA-143/145 cluster.2010

    • Author(s)
      Iio A, Nakagawa Y, Hirata I, Naoe T, Akao Y.
    • Journal Title

      Mol Cancer. 9

      Pages: 136-146

    • NAID

      120006341933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] Microvesicle-mediated RNA Molecule Delivery System Using Monocytes/Macrophages.2010

    • Author(s)
      Akao Y, Iio A, Itch T, Noguchi S, Itch Y, Ohtsuki Y, Naoe T.
    • Journal Title

      Mol Ther. 19

      Pages: 395-359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] Decreased expression of microRNAs-143 and-145 in human gastric cancers.2009

    • Author(s)
      Takagi T, Iio A, Nakagawa Y, Naoe T, Tanigawa N, Akao Y.
    • Journal Title

      Oncology 77

      Pages: 12-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] MicroRNA-141 and-200a are involved in bone morphogenetic protein-2-induced mouse Pre-osteoblast differentiation by targeting distal-less homeobox 5.2009

    • Author(s)
      Ito T, Nozawa Y, Akao Y
    • Journal Title

      JBiol Chem 284

      Pages: 19272-19279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] Role of microRNA-143 in Fas-mediated apoptosis in human T-cell leukemia Jurkat cells.2009

    • Author(s)
      Akao Y, Nakagawa Y, Iio A, Naoe T.
    • Journal Title

      Leukemia Res 33

      Pages: 1530-1538

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] Decreased expression of microRNAs-143 and-145 in human gastric cancers2009

    • Author(s)
      Takagi T, Iio A, Nakagawa Y, Naoe T, Tanigawa N, Akao Y
    • Journal Title

      Oncology 77

      Pages: 12-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] Role of microRNA-143 in Fas-mediated apoptosis in human T-cell leukemia Jurkat cell2009

    • Author(s)
      Akao Y, Nakagawa Y, Iio A, Naoe T
    • Journal Title

      Leukemia Research 33

      Pages: 1530-1538

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] Decreased expression of microRNAs-143 and -145 in human gastric cancers2009

    • Author(s)
      Takagi. T., Iio. A., Nakagawa. Y., Naoe. T., Tanigawa. N., Akao. Y
    • Journal Title

      Oncology 77

      Pages: 12-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] B細胞腫瘍と microRNAs2008

    • Author(s)
      赤尾幸博、中川義仁、直江知樹
    • Journal Title

      科学評論社 血液・腫瘍科 第56巻

      Pages: 617-624

    • NAID

      40019063333

    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] Effects of miR-34a on Cell Growth and Chemoresistance in Prostate Cancer PC3 Cells.2008

    • Author(s)
      Fujita Y, Kojima K, Hamada N, Ohhashi R, Akao Y, Nozawa Y, Deguchi T, Itch M.
    • Journal Title

      Biochem Biophys Res Commun. 377

      Pages: 114-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Journal Article] Structural insight of human DEAD-box protein rck/p54 into its substrate recognition with conformational changes.2006

    • Author(s)
      Matsui T, Hogetsu K, Usukura J, Sato T, Kumasaka T, Akao Y, Tanaka N.
    • Journal Title

      Genes Cells (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590334
  • [Journal Article] Human DEAD-box/RNA helicase rck/p54 contributes to maintenance of cell growth by affecting cell cycle in cultured cells2006

    • Author(s)
      Akao Y, Ohguchi K, Nakagawa Y, et al.
    • Journal Title

      Int J Oncology (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590334
  • [Journal Article] A human DEAD-box RNA helicase, rck/p54 : Dynamic substrate recognitions and influence on translation2006

    • Author(s)
      Matsui T, Usukura J, Akao Y, Tanaka N, et al.
    • Journal Title

      Genes to Cells (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590334
  • [Journal Article] A human DEAD-box RNA helicase, rck/p54 : Dynamic substrate recognitions and influence on translation2006

    • Author(s)
      Matsui T, Usukura J, Akao Y, Tanaka N. et al.
    • Journal Title

      Genes to Cells In press

    • Data Source
      KAKENHI-PROJECT-16590334
  • [Journal Article] Human DEAD-box/RNA helicase rck/p54 contributes to maintenance of cell growth by affecting cell cycle in cultured cells.2006

    • Author(s)
      Akao Y, Matsumoto K, Ohguchi K, Nakagawa Y.
    • Journal Title

      Int J Oncol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590334
  • [Journal Article] Expression of the DEAD-box/RNA helicase rck/p54 in mouse tissues : Implications for heterogeneous protein expression2006

    • Author(s)
      Akao Y, Nakagawa Y.
    • Journal Title

      J Histochem Cytochem (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590334
  • [Journal Article] Expression of the DEAD-box/RNA Helicase rck/p54 in Mouse Tissues : Implications for Heterogeneous Protein Expression.2006

    • Author(s)
      Akao Y, Nakagawa Y.
    • Journal Title

      J Histochem Cytochem (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590334
  • [Journal Article] Human DEAD-box/RNA helicase rck/p54 contributes to maintenance of cell growth by affecting cell cycle in cultured cells2006

    • Author(s)
      Akao Y, Ohguchi K, Nakagawa Y et al.
    • Journal Title

      Int J Oncology In press

    • Data Source
      KAKENHI-PROJECT-16590334
  • [Journal Article] High expression of sphingosine kinase 1 and S1P receptors in chemotherapy-resistant prostate cancer PC3 cells and their camptothecin-induced up-regulation.2006

    • Author(s)
      Akao, Y., et al.
    • Journal Title

      Biochem.Biophys.Res.Commun. 342

      Pages: 1284-1290

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390098
  • [Journal Article] Expression of the DEAD-box/RNA helicase rck/p54 in mouse tissues : Implications for heterogeneous protein expression2006

    • Author(s)
      Akao Y, Nakagawa Y.
    • Journal Title

      J Histochem Cytochem In press

    • Data Source
      KAKENHI-PROJECT-16590334
  • [Journal Article] Involvement of rck/p54, a DEAD-box RNA helicase, in gametogenesis and early embryogenesis of mice2005

    • Author(s)
      Matsumoto K, Kwon O-Y, Kim H, Akao Y
    • Journal Title

      Dev Dyn In press

    • Data Source
      KAKENHI-PROJECT-16590334
  • [Journal Article] Expression of rck/p54, a DEAD-box RNA helicase, in gametogenesis and early embryogenesis of mice.2005

    • Author(s)
      Matsumoto K, Kwon OY, Kim H, Akao Y
    • Journal Title

      Dev Dyn 233

      Pages: 1149-1156

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590334
  • [Journal Article] Crystallization and X-ray analysis of the N-terminal core domain of a tumour-associated human DEAD-box RNAhelicase, rck/p54.2004

    • Author(s)
      Matsui T, Hogetsu K, Akao Y, Tanaka M
    • Journal Title

      Acta Crystallogr D Biol Crystallogr 60

      Pages: 156-159

    • Data Source
      KAKENHI-PROJECT-16590334
  • [Presentation] 難治性固形癌に対するmicroRNA創薬の可能性2020

    • Author(s)
      谷口高平、猪俣陽介、和田俊一、浦田秀仁、宮田完二郎、内山和久、赤尾幸博
    • Organizer
      第53回 制癌剤適応研究会
    • Data Source
      KAKENHI-PROJECT-18K08660
  • [Presentation] 乳癌高転移マウス細胞に対する合成microRNA-145-5pの抗がん効果の検証2020

    • Author(s)
      冨永智、谷口高平、柴田雅朗、小村和正、赤尾幸博、木村光誠、猪俣陽介、碇絢菜、前沢早紀、岩本充彦、内山和久
    • Organizer
      第58回 日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08660
  • [Presentation] microRNA創薬による難治性固形癌の克服に向けた独自ツールの開発と活用2020

    • Author(s)
      谷口高平、内山和久、赤尾幸博
    • Organizer
      第24回 日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08660
  • [Presentation] 高転性移乳癌に対する合成microRNA-145-5pの抗癌作用の検討2020

    • Author(s)
      谷口高平、柴田雅朗、伊藤裕子、猪俣陽介、小村和正、赤尾幸博、内山和久
    • Organizer
      第79回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K08660
  • [Presentation] 乳癌高転移マウスモデルにおけるmiR-145-5pの抗癌作用について2019

    • Author(s)
      冨永智、谷口高平、柴田雅朗、岩本充彦、赤尾幸博、内山和久
    • Organizer
      第57回 日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08660
  • [Presentation] メカニカルストレス負荷骨細胞から分泌されたexosomeは 破骨細胞の分化を誘導する2018

    • Author(s)
      伊藤智広,赤尾幸博
    • Organizer
      第138回日本薬学会
    • Data Source
      KAKENHI-PROJECT-15K12714
  • [Presentation] MicroRNAの臓器特異性と新規がん遺伝子PTBP1の機能解析2018

    • Author(s)
      谷口高平、赤尾幸博、内山和久
    • Organizer
      第51回 制癌剤適応研究会
    • Data Source
      KAKENHI-PROJECT-15K10120
  • [Presentation] 胃液由来細胞外小胞の抽出と機能解析2018

    • Author(s)
      駕田修史、谷口高平、猪俣陽介、倉永祐希、伊藤裕子、赤尾幸博、内山和久
    • Organizer
      第77回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K10521
  • [Presentation] microRNA発現を利用した骨芽細胞分化評価法の検討2017

    • Author(s)
      伊藤智広,赤尾幸博
    • Organizer
      日本農芸化学会
    • Place of Presentation
      京都女子大学(京都府・京都市)
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-15K12714
  • [Presentation] Oncogene RNA helicase DDX6 promotes the process of c-Myc expression in gastric cancer cells2017

    • Author(s)
      谷口高平、杉戸信彦、田尻下敏弘、二村学、吉田和弘、内山和久、赤尾幸博
    • Organizer
      第76回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15K10120
  • [Presentation] がん特異的代謝におけるmiR-34aの機能解析2017

    • Author(s)
      谷口高平、杉戸信彦、赤尾幸博、内山和久
    • Organizer
      第21回 日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K10120
  • [Presentation] 新規がん遺伝子PTBP1の機能及び発現調節機構の解析2016

    • Author(s)
      谷口高平、杉戸信彦、倉永祐希、熊崎実南、篠原悠、内山和久、赤尾幸博
    • Organizer
      日本がん分子標的治療学会
    • Place of Presentation
      別府国際コンベンションセンター、別府市、大分県
    • Year and Date
      2016-05-31
    • Data Source
      KAKENHI-PROJECT-15K10120
  • [Presentation] メカニカルストレス負荷骨芽細胞分化におけるmiRNAの役割2016

    • Author(s)
      伊藤智広,田丸浩,赤尾幸博
    • Organizer
      日本生化学学会 中部支部例会
    • Place of Presentation
      三重大学(三重県・津市)
    • Data Source
      KAKENHI-PROJECT-15K12714
  • [Presentation] Pyruvate kinase isoforms are dysregulated by organ-specific microRNA in cancer development.2016

    • Author(s)
      谷口高平, 杉戸信彦, 内山和久, 赤尾幸博
    • Organizer
      第75回, 日本癌学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K10120
  • [Presentation] がん特異的エネルギー代謝を標的としたRNA創薬2016

    • Author(s)
      谷口高平, 高井朋聡, 吉川勇希, 杉戸信彦, 内山和久, 東治人, 赤尾幸博
    • Organizer
      日本核酸医薬学会 第2回年会
    • Place of Presentation
      東京理科大学葛飾キャンパス図書館大ホール
    • Year and Date
      2016-11-15
    • Data Source
      KAKENHI-PROJECT-15K10120
  • [Presentation] 新規重要がん遺伝子PTBP1の機能及び発現調節機構の解析2016

    • Author(s)
      谷口高平,内山和久,赤尾幸博
    • Organizer
      第4回 がんと代謝研究会
    • Place of Presentation
      鹿児島県民交流センター
    • Year and Date
      2016-07-07
    • Data Source
      KAKENHI-PROJECT-15K10120
  • [Presentation] TKI非感受性株に対するAIC-47の抗がん作用2015

    • Author(s)
      篠原悠、南陽介、熊崎実南、谷口高平、直江知樹、赤尾幸博.
    • Organizer
      第74回日本癌学会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25293218
  • [Presentation] マウス乳癌細胞はVEGF-C前駆体を内包したmicrovesiclesを分泌する2015

    • Author(s)
      伊藤裕子、柴田雅朗、前村憲太朗、谷口高平、赤尾幸博、大槻勝紀
    • Organizer
      第74回日本癌学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-10
    • Data Source
      KAKENHI-PROJECT-25462003
  • [Presentation] Ph陽性白血病に対するAIC-47のbcr-abl転写抑制とイマチニブの併用効果2015

    • Author(s)
      篠原悠、熊崎実南、谷口高平、倉永祐希、岩附綾子、酒井美来、直江知樹、赤尾幸博.
    • Organizer
      第19回日本がん分子標的治療学会
    • Place of Presentation
      松山全日空ホテル(愛媛県松山市)
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-25293218
  • [Presentation] イマチニブ非感受性白血病に対する新規脂肪酸誘導体AIC-47の増殖抑制作用2015

    • Author(s)
      篠原悠、南陽介、直江知樹、赤尾幸博.
    • Organizer
      第53回日本癌治療学会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2015-10-29
    • Data Source
      KAKENHI-PROJECT-25293218
  • [Presentation] マウス乳癌細胞はprecursor VEGF-C を内包したexosomeを放出する2014

    • Author(s)
      伊藤裕子、ナビル・イード、柴田雅朗、赤尾幸博、大槻勝紀
    • Organizer
      第119回日本解剖学会総会
    • Place of Presentation
      自治医科大学キャンパス
    • Data Source
      KAKENHI-PROJECT-25462003
  • [Presentation] 大腸がんにおけるmicroRNA-92aのバイオマーカーとしての可能性とその機能2013

    • Author(s)
      辻村 野乃香、山田 名美、赤尾 幸博
    • Organizer
      第15回日本RNA学会
    • Place of Presentation
      ひめぎんホール(愛媛県松山市)
    • Data Source
      KAKENHI-PROJECT-24659157
  • [Presentation] DDX6 posttranscriptionally downregulates miR-143/145 expression through host gene, NCR143/145, in cancer cells2011

    • Author(s)
      Akio Iio and Yukihiro Akao
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-04
    • Data Source
      KAKENHI-PROJECT-23590483
  • [Presentation] DDX6 posttranscriptionally downregulates miR-143/145 expression through host gene, NCR143/145, in cancer cells.2011

    • Author(s)
      A.Iio and Y.Akao
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Data Source
      KAKENHI-PROJECT-23590483
  • [Presentation] マイクロ齢Aを用いた比較腫瘍学2010

    • Author(s)
      野口俊助、丸尾幸嗣、赤尾幸博
    • Organizer
      第69回日本癌学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] マイクロ齢A-34の脱制御と抗癌剤耐喧2010

    • Author(s)
      赤尾幸博、野口俊介、飯尾明夫
    • Organizer
      第12回目本RNA学会年会
    • Place of Presentation
      一橋記念講堂 東京
    • Year and Date
      2010-07-27
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] がん抑制マイクロRNA-143、-145の発癌ネットワーク2010

    • Author(s)
      赤尾幸博
    • Organizer
      ゲノムケミストリー
    • Place of Presentation
      近畿大学本部キャンパス
    • Year and Date
      2010-03-27
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] Dysregulation of miR-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells2010

    • Author(s)
      Akao Y, Noguchi S, Naoe T
    • Organizer
      第69回日本癌学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] microRNA-208によるBMP-2誘導マウス前駆骨芽細胞分化調節2010

    • Author(s)
      伊藤智広、竹出秀、赤尾幸博
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] 創薬分野からみた比較腫瘍学への期待:microRNAを用いた比較腫瘍学から創薬ヘマイクロRNA2010

    • Author(s)
      赤尾幸博
    • Organizer
      日本化学会第90春季年会イブニングセッション
    • Place of Presentation
      日本獣医生命科学大学(東京都武蔵野市)
    • Year and Date
      2010-03-28
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] Transcriptional and post-translational regulation of miR-143/145 expression through host gene, NCR143/145 in cancers2010

    • Author(s)
      飯尾明夫、赤尾幸博
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] Fasを介したT細胞のアポトーシスにおけるmiR-143の関与2010

    • Author(s)
      赤尾幸博、野口俊助、直江知樹
    • Organizer
      第1回日本Cel⊥Death学会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-07-31
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] 家族性大腸腺腫症におけるマイクロRNA-143、-145,34aの発現2010

    • Author(s)
      中川義仁、赤尾幸博、平田一郎
    • Organizer
      第69回日本癌学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] 細胞を用いた新規なRNA医薬搬送システムの構築-患者の白血球に目的のRNA分子を導入し体内に戻す-岐阜大学大学院連合創薬2010

    • Author(s)
      赤尾幸博
    • Organizer
      第9回バイオテクノロジー国際会議
    • Place of Presentation
      東京
    • Year and Date
      2010-07-02
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] microRNA-143/145クラスターを介在するノンコーディングRNAの同定2009

    • Author(s)
      飯尾明生、直江知樹、赤尾幸博
    • Organizer
      第71回目本癌学会総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] ヒト大腸癌細胞株DLD・1におけるmicroRNA・34aの5・FU耐性への関与2009

    • Author(s)
      高城武嗣、赤尾幸博
    • Organizer
      第69回目本癌学会総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] 細胞死誘導シグナルにおけるmicroRNA・143、・145の発現2009

    • Author(s)
      赤尾幸博、飯尾明夫、中川義仁、直江知樹
    • Organizer
      第70回目本癌学会総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] 細胞死誘導シグナルにおけるmicroRNA-143、-145の発現2009

    • Author(s)
      赤尾幸博、飯尾明夫、中川義仁、直江知樹
    • Organizer
      第68回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] 家族性大腸腺腫症におけるmicroRNA・143、-145、-7の発現2009

    • Author(s)
      中川義仁、赤尾幸博、平田一郎
    • Organizer
      第68回目本癌学会総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] 消化管腫瘍におけるマイクロRNA-143、-145の発癌への関与2008

    • Author(s)
      赤尾幸博, 中川義仁, 他4名
    • Organizer
      第67回 日本癌学会総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] Dysregulation of miR-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells

    • Author(s)
      赤尾幸博、野口俊助、直江知樹
    • Organizer
      第69回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] シンポジウム:伴侶動物がん臨床の新たな展開:医療への橋渡しを目指す『比較腫瘍学』の基盤形成

    • Author(s)
      赤尾幸博
    • Organizer
      第149回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-20590419
  • [Presentation] Chemically-modified synthetic microRNA-205 inhibits the growth of melanoma cells and a clinical trials in canine melanomas

    • Author(s)
      Yukihiro Akao
    • Organizer
      American Association Cancer Research in Shanghai
    • Place of Presentation
      上海、中国
    • Year and Date
      2014-10-08 – 2014-10-12
    • Data Source
      KAKENHI-PROJECT-24659157
  • [Presentation] イヌ自然発生メラノーマに対する化学修飾人工microRNA-205の治療効果: 局所投与による予備的検討

    • Author(s)
      森 崇, 野口俊助, 中島礼美, 北出幸夫, 赤尾幸博, 村上麻美, 丸尾幸嗣
    • Organizer
      第157回日本獣医学会学術集会
    • Place of Presentation
      北海道大学
    • Year and Date
      2014-09-09 – 2014-09-12
    • Data Source
      KAKENHI-PROJECT-24580459
  • 1.  NOZAWA Yoshinori (10021362)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  BANNO Yoshiko (50116852)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  UCHIYAMA Kazuhisa (80232867)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 22 results
  • 4.  OTSUKI Yoshinori (50140166)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 5.  TANAKA Masashi (60155166)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  IIO Akio (80344349)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 19 results
  • 7.  NAKAGAWA Yoshihito (60372108)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 8.  USUKURA Jiro (30143415)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 9.  Itoh Tomohiro (30435854)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 10.  UEDA Hiroshi (50253779)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 11.  NOGUCHI Shunsuke (10701295)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 12.  TUJIMOTO Yoshihide (70132735)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  KUSAKABE Moriaki (60153277)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  OHGUCHI Kenji (80359257)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  MATSUMOTO Kenji (60288701)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 16.  TANIGUCHI Kohei (70779686)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 21 results
  • 17.  上田 龍三 (20142169)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  高橋 利忠 (00124529)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  瀬戸 加大 (80154665)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  吉田 均 (30303548)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  MORI Takashi (40402218)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 22.  SAKAI Hiroki (40283288)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 23.  NAOE Tomoki (50217634)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 24.  KIYOI Hitoshi (90314004)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  HAYAKAWA Fumihiko (30402580)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 26.  SHIMADA Kazuyuki (50631503)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  TOMITA Akihiro (80378215)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  KOUMURA Sadaaki (80211233)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  Ito Yuko (40148432)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 30.  Shibata Masa-aki (10319543)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 31.  NABIL Eid (50570165)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  Lee Sang-Woong (40368080)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 33.  Asakuma Mitsuhiro (40559390)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  杉本 修 (00084822)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  中島 茂 (60188935)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  田中 信夫 (50032024)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 37.  田代 圭太郎 (20645527)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 38.  河合 英 (40465604)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  廣川 文鋭 (20322373)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  本田 諒
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  EID NabilA.S.
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  南 陽介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  北出 幸夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  浦田 秀仁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  杉山 剛志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  佐藤 克哉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to connect your ORCID iD to this researcher?
* This action can be performed only by the researcher themselves.

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi