TACHIBANA Hiroyuki 立花博之

… Alternative Names

立花博之タチバナヒロユキ

TCHIBANA Hiroyuki 立花博之

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Researcher Number	00241216
Other IDs
Affiliation (Current)	2025: 川崎医療福祉大学, 医療技術学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 川崎医療福祉大学, 医療技術学部, 准教授 2007 – 2010: 川崎医療福祉大学, 医療技術学部, 講師 2004 – 2005: 川崎医療短期大学, 臨床工学科, 講師 1999 – 2003: Kawasaki College of Allied Health Professions, Dept. of Applied Medical Engineering, Instructor, 臨床工学科, 助手 2002: Kawasaki Medical College of Allied Health Professions, Medical Engineering, Assistant 1993 – 1998: Kawasaki College Of Allied Health Professions, Dept.of Applied Medical Engineeri, 医用電子技術科, 助手 1992: 川崎医療短期大学, 医用電子技術科, 助手補
Review Section/Research Field	Principal Investigator Biomedical engineering/Biological material science / Circulatory organs internal medicine / Biomedical engineering/Biological material science Except Principal Investigator Circulatory organs internal medicine / Biomedical engineering/Biological material science / Biomedical engineering/Biological material science / Basic Section 58010:Medical management and medical sociology-related / 計測・制御工学
Keywords	Principal Investigator ずり応力 / 局所血流構造 / 共焦点型レーザ走査顕微鏡 / Velocity mapping / glomerular microcirculation / CCD Microscope / 光マーカー / 血流動態 / 腎微小循環 / 高速度CCD生体顕微鏡 … More / 糸球体毛細管 / 速度マッピング / 糸球体内微小循環 / ペンシルレンズ / CCD生体顕微鏡 / 小型体外循環システム / カプセル型人工赤血球 / 局所血流分布 / 冠微小循環 / リアルタイムグラメトリシステム / 冠循環 / 貫通枝血管 / 心筋微小血管造影 / 細胞間隙 / 培養内皮細胞 / 電気インピーダンス計測 / 光マーカ / 高速度カメラ内臓CCD生体顕微鏡 / 微細粒子光マーカ / 高速度カメラ内蔵CCD生体顕微鏡 / メカニカルストレス / 心筋マイクロメカニクス / 局所心筋マイクロストレイン / 脂質移動 / ストレスファイバ … More Except Principal Investigator 微小循環 / 細動脈 / Flow visualization / CCD microscope / Cardiac lymphatics / myocardial ischemia / 心筋虚血 / Microcirculation / 冠微小循環 / 内皮細胞 / asymmetric dimethylarginine (ADMA) / L-arginine / superoxide / 血液透析 / microcirculation / 分子血流トレーサ / Venule / Arteriole / 細静脈 / 一酸化窒素(NO) / 流路異常検知 / 医療安全 / 人工知能 / 流路異常 / 異常検知 / 機械学習 / 回路内凝血 / 抜針事故 / 在宅血液透析 / 持続的腎代替療法 / 臨床工学 / oxidized LDL / tetrahydrobiopterin (BH_4) / oxidative stress / nitric oxide (NO) / hemodialysis / センサー / ADMA / 高血圧 / 血液汚染 / asymmetric dimethylarginine(ADMA) / テトラハイドロビオプテリン(BH_4) / スーパーオキサイド / 酸化LDL / tetrahdrobiopterin (BH_4) / 酸化ストレス / リンパ流速 / high speed CCD生体顕微鏡 / 心臓リンパ管 / Caediac lymphtic / 血液交叉潅流 / 血流不均一性 / 血液マイクロレオロジー / 心筋微小循環障害 / 人工赤血球 / デジタルラジオグラフィ / 分子トレーサ / 心筋潅流不均一性 / 血液レオロジー / ラット交叉潅流モデル / microcompuled tomography / synchrotron radiation / coronary vessels / マイクロCT / 放射光 / 冠血管 / vascular response / myogenic regulation / pulse pressure / mechanical stress / arteriole / subendocardium / 血管反応 / 筋原性調節 / 拍動圧 / メカニカルストレス / 心内膜側 / microregional ischemia / molecular flow tracer / local homogeneity / global heterogeneity / myocardial blood flow / デスメチルイミプラン / 微小循環障害 / 局所一様性 / 全体不均一性 / 心筋内血流 / microflow-imaging / heterogeneity / RI molecular tracer / intramyocardial flow distribution / microcirculatory regulation / R1分子血流トレーサ / 不均一性 / 血流マイクロイメージング / RI分子血流トレーサ / 心筋内血流分布 / 微小循環調節 / CCD-microscope / 微小冠循環 / ニトログリセリン / ニードル型CCD生体顕微鏡 / CCD-Microscope / 冠循環 / CCD生体顕微鏡 / FITC-dextran / Indocyanine green / Subendocardial vessels / Beating heart / Needle-probe video-microscope with a CCD camera / FITCデキストラン / インドシアニングリーン / 心内膜側血管 / 拍動心 / CCDマイクロスコープ / 電子顕微鏡 / レーザースキャン顕微鏡 / 血管鋳型 / 血流速度 / 冠動脈 / ナノメディスン / ナノバイオロジー / アクチンフィラメト / 動脈硬化 / ナノバイオロジー・ナノメディスン / 情報伝達 / 白血球 / ミオシン / アクチン / アクチン・ミオシン架橋 / SPring-8 / フィジオーム / レーザマニピュレーション / 細胞内情報伝達 / 細胞応答機構 / レーザーマニピュレーション / 力学刺激 / 血管内皮細胞 / ずり応力 Less

Development of a blood circuit trouble detection system during haemodialysis using AI technology and waveform analysis.
- Principal Investigator
  
  ONO JUNICHI
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Kawasaki University of Medical Welfare
Real time and in situ observation of actin structure in migrating leukocyte
- Principal Investigator
  
  KATAOKA Noriyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki University of Medical Welfare
Promotion of cardiovascular physiome focusing on coronary microcirculation and myocardial crossbridge dynamics
- Principal Investigator
  
  KAJIYA Fumihiko
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki University of Medical Welfare
  Kawasaki College of Allied Health Professions
小型バイオポンプを用いた拍動心筋におけるカプセル型人工赤血球の微小循環の解析Principal Investigator
- Principal Investigator
  
  立花博之
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki College of Allied Health Professions
細胞表面および細胞内部への応力負荷に対する内皮細胞内情報伝達メカニズムの解析
- Principal Investigator
  
  MOCHIZUKI Seiichi, KATAOKA Noriyuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki College of Allied Health Professions
リアルタイムグラメトリシステムの開発と8GeV放射光心筋微小血管造影への応用Principal Investigator
- Principal Investigator
  
  立花博之
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki College of Allied Health Professions
Analysis of cardiac lymphatic dynamics in beating canine hearts using a high-speed CCD microscope
- Principal Investigator
  
  HIRAMATSU Osamu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki Medical College of Allied Health Professions
Analysis of cardiac lymphatic dynamics in beating canine hearts using a high-speed CCD microscope
- Principal Investigator
  
  HIRAMATSU Osamu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki Medical College of Allied Health Professions
Evaluation of dynamic changes of nitric oxide and oxidative stress in hemodialysis patients
- Principal Investigator
  
  MOCHIZUKI Seiichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki College of Allied Health Professions
ECISによる培養血管内皮細胞の動態挙動の解析と評価Principal Investigator
- Principal Investigator
  
  立花博之
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki College of Allied Health Professions
Development of Pencil-type CCD Microscope for evaluating of renal glomerular microcirculation with normal and hypertensive RatPrincipal Investigator
- Principal Investigator
  
  TACHIBANA Hiroyuki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki College of Allied Health Professions
Functional Morphology of Coronary Arteriol.es in Relation to Coronary Microcirculatory Disturbance by Micro-imaging Techniques
- Principal Investigator
  
  GOTO Masami
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki College of Allied Health Professions
微細粒子を用いた局所心筋マイクロストレインの解析・評価Principal Investigator
- Principal Investigator
  
  立花博之
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki College of Allied Health Professions
Endothelium-dependent and -independent responses of coronary arteriole to pulsatile mechanical stress in vivo
- Principal Investigator
  
  GOTO Masami
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki College of Allied Health Professions
Three-dimensional imaging of myocardial blood flow with microcomputed
- Principal Investigator
  
  JIKUYA Kazuaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  計測・制御工学
- Research Institution
  Kawasaki College of Allied Health Professions
Development of 3-D Evaluation System of Microheterogeneity of Intramyocardial Flow Using Molecular Flow Tracers
- Principal Investigator
  
  GOTO Masami
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki College of Allied Health Professions
Analysis of vasodilated effect of nitroglycerin on microvessels
- Principal Investigator
  
  HIRAMATSU Osamu
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki College of Allied Health Professions
共焦点型レーザ走査顕微鏡による単球及びLDLの血管壁内動態の3次元的解析Principal Investigator
- Principal Investigator
  
  立花博之
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki College of Allied Health Professions
Developement of side-on typed needle-probe for CCD microscope
- Principal Investigator
  
  HIRAMATSU Osamu
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki College of Allied Health Professions
共焦点型レーザ走査顕微鏡による血管分岐部微細構造の三次元的解析Principal Investigator
- Principal Investigator
  
  立花博之
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki College of Allied Health Professions
血管内皮配列と微細形態観察のための冠血管鋳型・レーザースキャン顕微鏡解析法の開発
- Principal Investigator
  
  後藤真己 (後藤真巳)
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki College of Allied Health Professions
Study on the subendocardial ischemia using a high resolution needle-probe video-microscope with a CCD camera
- Principal Investigator
  
  GOTO Masami
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki College Of Allied Health Professions

All 2008 2007 2005

All Journal Article

[Journal Article] Development of high-resolution 4D in vivo-CT for visualization of cardiac and respiratory deformations of small animals2008
- Author(s)
  Sera T, Yokota H, Fujisaki K, Fukasaku K, Tachibana H, Uesugi K, Yagi N, Himeno R
- Journal Title
  
  Phys Med Biol. 53(16)
  
  Pages: 4285-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200033
[Journal Article] Microheterogeneity of regional myocardial blood flows in low-perfused rat hearts evaluated by double-tracer digital radiography2007
- Author(s)
  Matsumoto T, Asano T, Takemoto M, Tachibana H, Ogasawara Y, Kajiya F
- Journal Title
  
  Appl Radiat Isot. 65(8)
  
  Pages: 910-917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200033
[Journal Article] Microheterogeneity of regional myocardial blood flows in low-perfused rathearts evaluated by double-tracer digital radiography2007
- Author(s)
  Matsumoto T, Asano T, Takemoto M, Tachibana H, Ogasawara Y, Kajiya F
- Journal Title
  
  Appl Radiat Isot 65(8)
  
  Pages: 910-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200033
[Journal Article] Regional myocardial perfusion under exchange transfusion with liposomal hemoglobin : in vivo and in vitro studies using rat hearts.2005
- Author(s)
  Matsumoto T, Asano T, Mano K, Tachibana H, Todoh M, Tanaka M, Kajiya F
- Journal Title
  
  Am J Physiol Heart Circ Physiol 288(4)
- Data Source
  KAKENHI-PROJECT-16700372
[Journal Article] Direct measurement of nipradilol-derived nitric oxide in the vascular wall of canine femoral arteries.2005
- Author(s)
  Mochizuki S, Chiba Y, Hiramatsu O, Tachibana H, Nakamoto H, Toyota E, Ogasawara Y, Kajiya F.
- Journal Title
  
  Heart Vessels. 20・4
  
  Pages: 175-178
- Data Source
  KAKENHI-PROJECT-17200033

1. MATSUMOTO Takeshi (30249560)

# of Collaborated Projects: 15 results

# of Collaborated Products: 0 results
2. GOTO Masami (50148699)

# of Collaborated Projects: 13 results

# of Collaborated Products: 0 results
3. HIRAMATSU Osamu (50208849)

# of Collaborated Projects: 13 results

# of Collaborated Products: 1 results
4. MOCHIZUKI Seiichi (60259596)

# of Collaborated Projects: 12 results

# of Collaborated Products: 1 results
5. KAJIYA Fumihiko (70029114)

# of Collaborated Projects: 11 results

# of Collaborated Products: 3 results
6. OGASAWARA Yasuo (10152365)

# of Collaborated Projects: 7 results

# of Collaborated Products: 3 results
7. KATAOKA Noriyuki (20250681)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
8. TSUJIOKA Katsuhiko (30163801)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
9. HASHIMOTO Ken (80341080)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. YAGI Naoto (80133940)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. SUGIURA Seiryo (10272551)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. HIMENO Ryutaro (60342838)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
13. SUGA Hiroyuki (90014117)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. SHIMIZU Juichiro (80294403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MOHRI Satoshi (00294413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAKAMURA Kazufumi (10335630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NINOMIYA Yoshifumi (70126241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KOBAYASHI Naoya (10325102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. JIKUYA Kazuaki (90206350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. YADA Toyotaka (00210279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. FUJIMOTO Katsukuni (80106351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KASHIHARA Naoki (10233701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KIMOTO Masumi (40108866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. ONO JUNICHI (50435351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 豊田英嗣 (30248215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 逸見知弘 (00413849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TACHIBANA Hiroyuki 立花 博之

立花 博之 タチバナ ヒロユキ

TCHIBANA Hiroyuki 立花 博之

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小型バイオポンプを用いた拍動心筋におけるカプセル型人工赤血球の微小循環の解析Principal Investigator

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リアルタイムグラメトリシステムの開発と8GeV放射光心筋微小血管造影への応用Principal Investigator

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ECISによる培養血管内皮細胞の動態挙動の解析と評価Principal Investigator

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Development of Pencil-type CCD Microscope for evaluating of renal glomerular microcirculation with normal and hypertensive RatPrincipal Investigator

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微細粒子を用いた局所心筋マイクロストレインの解析・評価Principal Investigator

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TACHIBANA Hiroyuki 立花博之

立花博之タチバナヒロユキ

TCHIBANA Hiroyuki 立花博之