HITOSHI OHISHI 大石仁

… Alternative Names

OHISHI Hitoshi 大石仁

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Researcher Number	00252461
Affiliation (Current)	2023: 帝京科学大学, 医療科学部, 教授
Affiliation (based on the past Project Information) *help	2007 – 2013: Aichi Medical University, School of Medicine, Department of Anatomy, Associate Professor 2006: 愛知医科大学, 医学部, 助教授 1999 – 2000: 関西医科大学, 医学部, 講師 1996 – 1997: 京都大学, 医学部, 助手 1995 – 1996: 京都大学, 医学研究科, 助手 1994: 京都大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Nerve anatomy/Neuropathology Except Principal Investigator Nerve anatomy/Neuropathology / 疼痛学 / Rehabilitation science/Welfare engineering / Pain science
Keywords	Principal Investigator グルタミン酸受容体 / 抗体 / 免疫組織化学 / 中枢神経 / ラット / in situ hybridization / ゴルジ細胞 / 小脳 / グルタミン酸 / 脊髄 … More / 一次求心性線維 / 線条体 / Gタンパク質 / 受容体 / 大脳基底核 / Striatum / G-protein / Receptor … More Except Principal Investigator 慢性痛 / 痛み / 動物モデル / 筋障害 / 自律神経 / グリア / 免疫組織 / GABA / 免疫・炎症 / 分子生物学 / 不動化 / 自発運動 / 運動療法 / 神経科学 / 予防 / グリシン / グルタミン酸受容体 / ペプチド / 三叉神経系 / 小脳 / 線条体 / 嗅覚系 / セロトニン / P物質受容体 / 三叉神経核 / 痛覚 / 嗅覚 / オピオイド受容体 / エンケファリン / 免疫組織化学 / 逆行性標識法 / Glycine / Glutamate receptor / Peptide / Trigeminal system / Cerebellum / Striatum / Olfactory system / 遺伝子 / マウス / ノシセプチン / 学習・記憶機構 / イオンチャネル / cDNAサブトラクション法 / β-galactosidase / gene targeting / peptide receptor system / knockout mice / nociceptin / 筋傷害 / 分子生物 / 脊髄 / chronic pain / animal model / muscle damage / immunohistochemistry / molecular biology / autonomic nervous system / spinal cord / glia Less

Development of exercise prescription for the prevention of chronic pain onset associated with hindlimb immobilization
- Principal Investigator
  
  OHMICHI MIKA
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Aichi Medical University
Exploration for the factors implicated in pathogenesis and maintenance of chronic pain.
- Principal Investigator
  
  IWASE Satoshi, KUMAZAWA Takao (熊沢孝朗)
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  疼痛学
- Research Institution
  Aichi Medical University
Systemic and molecular analysis on the pathology of newly-developed myopathic chronic pain models
- Principal Investigator
  
  KUMAZAWA Takao
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Aichi Medical University
Nociceptin receptor-deficient mice : distribution of nociceptin precursor protein and receptor in brain and spinal cord
- Principal Investigator
  
  SUGIMOTO Tetsuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kansai Medical University
ORPHAN G-PROTEIN COUPLED RECEPTORS IN THE STRIATUMPrincipal Investigator
- Principal Investigator
  
  OHISHI Hitoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kansai Medical University
Gタンパク質結合型グルタミン酸受容体mGluR7の中枢神経系内分布の解析Principal Investigator
- Principal Investigator
  
  大石仁
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto University
Neuronal circuitry in relation with transmitters and their receptors
- Principal Investigator
  
  MIZUNO Noboru
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  KYOTO UNIVERSITY
抗メタボトロピックグルタミン酸受容体抗体による小脳介在ニューロンの免疫組織化学Principal Investigator
- Principal Investigator
  
  大石仁
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto University
Gタンパク質結合型グルタミン酸受容体mGluR4,mGluR7の中枢神経系内分布Principal Investigator
- Principal Investigator
  
  大石仁
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto University

All 2014 2013 2012 2009 2008

All Journal Article Presentation

[Journal Article] Activated spinal astrocytes are involved in the maintenance of chronic widespread mechanical hyperalgesia after cast immobilization2014
- Author(s)
  Mika Ohmichi
- Journal Title
  
  Mol Pain.
  
  Volume: 24 Pages: 1-13
- DOI
  10.1186/1744-8069-10-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23500628, KAKENHI-PROJECT-23590710, KAKENHI-PROJECT-24700565, KAKENHI-PROJECT-25750237, KAKENHI-PROJECT-25870884
[Journal Article] Two-week cast immobilization induced chronic widespread hyperalgesia in rats2012
- Author(s)
  Ohmichi Y, Sato J, Ohmichi M, Sakurai H, Yoshimoto T, Morimoto A, Hashimoto T, Eguchi K, Nishihara M, Arai YC, Ohishi H, Asamoto K, Ushida T, Nakano T, Kumazawa T
- Journal Title
  
  Eur J Pain
  
  Volume: 16 Pages: 338-348
- DOI
  10.1002/j.1532-2149.2011.00026.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500628
[Presentation] 脊髄アストロサイトの活性化はラット後肢のギプス固定後に出現する持続性の広範囲痛覚過敏に関与する2013
- Author(s)
  大道裕介, 大道美香, 大石仁
- Organizer
  第118回日本解剖学会総会・全国学術集会
- Place of Presentation
  香川
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-23500628
[Presentation] ギプス固定後慢性痛モデルラットの脊髄後角におけるc-Fosの両側性発現2012
- Author(s)
  大石仁, 大道美香, 大道裕介
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-23500628
[Presentation] ギプス固定後慢性痛モデルラットの脊髄後角におけるc-Fosの両側性発現2012
- Author(s)
  大石仁
- Organizer
  第177回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-23500628
[Presentation] ギプス固定後慢性痛モデルにおける機械的痛覚増強行動はMinocyclineにより減弱する2012
- Author(s)
  大道美香, 大道裕介, 大石仁
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-23500628
[Presentation] Inhibitory effects of minocycline, an inhibitor of spinal microglial activation, on widespread mechanical hyperalgesia in a rat model of cast immobilization2012
- Author(s)
  Mika Ohmichi, Yusuke Ohmichi, Hitoshi Ohishi
- Organizer
  14th World Congress on Pain
- Place of Presentation
  Milan( Italy)
- Year and Date
  2012-08-31
- Data Source
  KAKENHI-PROJECT-23500628
[Presentation] 下肢ギプス固定がもたらす慢性的痛み行動に伴う脊髄ミクログリア・アストロサイトの変化2009
- Author(s)
  大道裕介, 大道美香, 大石仁, 櫻井博紀, 吉本隆彦, 森本温子, 橋本辰幸, 江口国博, 山口佳子, 中野隆, 熊澤孝朗
- Organizer
  第114回日本解剖学会総会・全国学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20602009
[Presentation] Temporal and spatial changes of spinal glial cells in chronic pain model induced by the cast-immobilization.2008
- Author(s)
  大道美香, 大道裕介, 大石仁, 櫻井博紀, 吉本隆彦, 森本温子, 橋本辰幸, 牛田享宏, 山口佳子, 熊澤孝朗
- Organizer
  12th World Congress on Pain
- Place of Presentation
  Glasgow
- Data Source
  KAKENHI-PROJECT-20602009
[Presentation] Changes in pain behavior associated with the spinal glial activations in the chronic pain model by the plaster-immobilization.2008
- Author(s)
  大道裕介, 大道美香, 大石仁, 櫻井博紀, 吉本隆彦, 森本温子, 橋本辰幸, 牛田享宏, 山口佳子, 熊澤孝朗
- Organizer
  The 3rd Asian Pain Symposium
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-20602009
[Presentation] 下肢ギプス固定後に発症する慢性的痛み行動における脊髄グリア細胞の関与2008
- Author(s)
  大道裕介, 大道美香, 大石仁, 櫻井博紀, 吉本隆彦, 森本温子, 橋本辰幸, 江口国博, 牛田享宏, 山口佳子, 熊澤孝朗
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20602009

1. IWASE Satoshi (90184879)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. KUMAZAWA Takao (20022775)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. OHMICHI MIKA (30581079)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. OHMICHI Yusuke (50506673)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. SAKURAI Hiroki (60454419)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. EGUCHI Kunihiro (30113062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. USHIDA Takahiro (60304680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. KOZAKI Yasuko (20126882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MIZUNO Noboru (10025596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NOMURA Sakashi (60034188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TOKUNO Hironobu (40212071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TAKADA Masahiko (00236233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KANEKO Takeshi (90177519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SUGIMOTO Tetsuo (90144352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KASE Masahiko (10309221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. HOUTANI Takeshi (60241163)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SAKUMA Satoru (70309227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HONDA Takashi (20165608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 大迫洋治 (40335922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 橋本辰幸 (80367763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. YOSHIMOTO Takahiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
22. YAMAGUCHI Yoshiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
23. MORIMOTO Atsuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
24. 佐藤純

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HITOSHI OHISHI 大石 仁

OHISHI Hitoshi 大石 仁

Research Projects

Research Products

Co-Researchers

Development of exercise prescription for the prevention of chronic pain onset associated with hindlimb immobilization

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploration for the factors implicated in pathogenesis and maintenance of chronic pain.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Systemic and molecular analysis on the pathology of newly-developed myopathic chronic pain models

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Nociceptin receptor-deficient mice : distribution of nociceptin precursor protein and receptor in brain and spinal cord

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ORPHAN G-PROTEIN COUPLED RECEPTORS IN THE STRIATUMPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gタンパク質結合型グルタミン酸受容体mGluR7の中枢神経系内分布の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Neuronal circuitry in relation with transmitters and their receptors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

抗メタボトロピック グルタミン酸受容体抗体による小脳介在ニューロンの免疫組織化学Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gタンパク質結合型グルタミン酸受容体mGluR4,mGluR7の中枢神経系内分布Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Activated spinal astrocytes are involved in the maintenance of chronic widespread mechanical hyperalgesia after cast immobilization2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Two-week cast immobilization induced chronic widespread hyperalgesia in rats2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] 脊髄アストロサイトの活性化はラット後肢のギプス固定後に出現する持続性の広範囲痛覚過敏に関与する2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ギプス固定後慢性痛モデルラットの脊髄後角におけるc-Fosの両側性発現2012

Author(s)

Organizer

Place of Presentation

Year and Date

HITOSHI OHISHI 大石仁

OHISHI Hitoshi 大石仁

抗メタボトロピックグルタミン酸受容体抗体による小脳介在ニューロンの免疫組織化学Principal Investigator