Takimoto Hiroaki 滝本博明

… Alternative Names

滝本博明タキモトヒロアキ

TAKIMOTO Hiroaki 滝本博明

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Researcher Number	00253534
Other IDs
Affiliation (Current)	2025: 北里大学, 理学部, 講師
Affiliation (based on the past Project Information) *help	2019 – 2022: 北里大学, 理学部, 講師 2002 – 2010: 北里大学, 理学部, 講師 1999 – 2000: 北里大学, 理学部, 講師 1997: 九州大学, 生体防御医学研究所, 助手
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) Except Principal Investigator Bacteriology (including Mycology) / Bacteriology (including Mycology) / Basic Section 58080:Gerontological nursing and community health nursing-related / Kidney internal medicine
Keywords	Principal Investigator TLR2 / IL-17 / γδ型T細胞 / 肉芽腫 / 結核菌糖脂質 / 感染免疫 Except Principal Investigator IFN-γ / IL-12 / 結核菌糖脂質 / サイトカイン … More / モルモット / mycobacterial glycolipid / 単クローン抗体 / CD1 / HMGB-1 / NF-κB / Toll-like receptor / 皮膚バリア / 細菌 / 殺菌 / 手指衛生 / 抗ウイルス活性 / 抗真菌活性 / 抗菌活性 / 看護師 / 手湿疹 / スキンバリア / 角層水分量 / 抗菌 / TEWL / 噴霧型 / オゾン水 / monoclonal antibodies / Cytokines / Guinea pig / CD1b / monoclonal antibody / cytokine / guinea pigs / HESPERIDIN / NARINGIN / FLAVONOIDS / GALACTOSAMINE CHALLENGED MICE / S. typhimurium INFECTION / ENDOTOXIN SHOCK / ガラクトサミン負荷マウス / ヘスペリジン / ナリンジン / フラボノイド / D-ガラクトサミン負荷マウス / S.typhimurium感染 / エンドトキシンショック / LIPID RAFT / MACROPHAGE / BACTERIAL GLYCOLIPID / TOLL-LIKE RFCEPTOR / NF-kB / 脂質ラフト / マクロファージ / 結核菌由来糖脂質 / TLR / INNATE IMMUNITY / CELL WALL COMPONENTS / LIPOPOLYSACCHARIDE / TOLL-LIKE RECEPTOR / 先天性免疫 / 細菌構成成分 / リポ多糖 / T cell receptor / Cytokine / Cellular immunity / Tubulointerstitial damage / Knockout mouse / T細胞レセプター / 増殖因子 / 細胞性免疫 / 尿細管間質障害 / ノックアウトマウス / 感染免疫 Less

Medical applications of portable ozone water device for both maintenance of skin barrier function and hand hyagene in hospital-based nurses
- Principal Investigator
  
  NAKANO Toshiaki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58080:Gerontological nursing and community health nursing-related
- Research Institution
  St. Luke's International University
Antigen presentation and cytokine resposes against mycobial glycolipids.
- Principal Investigator
  
  KUMAZAWA Yoshio
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Iwaki Meisei University
Mechanism of granuloma formation by mycobacterial glycolipi dsPrincipal Investigator
- Principal Investigator
  
  TAKIMOTO Hiroaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kitasato University
IMMUNE RESPONSE TO GLYCOLIPIDS SEPARETED FROM MYCOBACTERIUM TUBERCULOSIS
- Principal Investigator
  
  KUMAZAWA Yoshio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kitasato University
IMMUNE RESPONSE TO GLYCOLIPIDS SEPARETED FROM MYCOBACTERIUM TUBERCULOSIS IN GUINEA PIG
- Principal Investigator
  
  KUMAZAWA Yoshio
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  KITASATO UNIVERSITY
THE ROLE OF HMGB-1 AS CYTOKINE IN INFECTION
- Principal Investigator
  
  HASUNUMA Ryoichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kitasato University
MOLECULAR MECHANISMS OF CROSSTALK BETWEEN MYCOBACTERIAL GLYCOLIPIDS AND RECEPTORS ON MACROPHAGES
- Principal Investigator
  
  KUMAZAWA Yoshio
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  KITASATO UNIVERSITY
ROLE OF TOLL-LIKE RECEPTOR-2 IN INNATE IMMUNITY
- Principal Investigator
  
  KUMAZAWA Yoshio
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  KITASATO UNIVERSITY
Elucidation of the immunological mechanism in tubulointerstitial damage. - investigation with knockout mouse
- Principal Investigator
  
  FUKUDA Kyoichi, 安藤高志
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  KYUSHU UNIVERSITY

All 2010 2009 2008 2006 2000 Other

All Journal Article Presentation

[Journal Article] Potentiation of murine innate immunity by α-galacturonosyl-type glycosphingolipids isolated from Sphingomonas yanoikuyae and S. terrae.2009
- Author(s)
  Kubota, M., H. Takimoto, M. Kaneko, J. Inoue, Y. Kumazawa
- Journal Title
  
  Immunopharmacol Immunotoxicol 31
  
  Pages: 363-369
- Data Source
  KAKENHI-PROJECT-20590454
[Journal Article] Potentiation of murine innate immunity by alpha-galacturonosyl-type glycosphingolipids isolated from Sphingomonas yanoikuyae and S. terrae.2009
- Author(s)
  Kubota M, Takimoto H, Kaneko M, Inoue J, Kumazawa Y.
- Journal Title
  
  Immunopharmacol Immunotoxicol. 31(3)
  
  Pages: 363-369
- Data Source
  KAKENHI-PROJECT-20590453
[Journal Article] Suppressive effects of the flavonoids quercetin and luteolin on the accumulation of lipid rafts after signal transduction via receptors.2008
- Author(s)
  Kaneko M, Takimoto H, Sugiyama T, Seki Y, Kawaguchi K, Kumazawa Y.
- Journal Title
  
  Immunopharmacol Immunotoxicol. 30(4)
  
  Pages: 867-882
- Data Source
  KAKENHI-PROJECT-20590453
[Journal Article] Suppressive effects of flavonoids quercetin and luteolin on lipid raft accumulation following signal transduction via receptors.2008
- Author(s)
  Kaneko, M., H. Takimoto, Y. Seki, K. Kawaguchi, Y. Kumazawa
- Journal Title
  
  Immunopharmacol Immunotoxicol 30
  
  Pages: 867-882
- Data Source
  KAKENHI-PROJECT-20590454
[Journal Article] Amelioration of skewed Th1/Th2 balance in tumor-bearing and asthma-induced mice by oral administration of Agaricus blazei extracts.2008
- Author(s)
  Takimoto H, Kato H, Kaneko M, Kumazawa Y.
- Journal Title
  
  Immunopharmacol Immunotoxicol. 30(4)
  
  Pages: 747-760
- Data Source
  KAKENHI-PROJECT-20590453
[Journal Article] Amelioration of skewed Th1/Th2 balance in tumor-bearing and asthma-induced mice by oral administration of Agaricus blazei extracts.2008
- Author(s)
  Takimoto, H., H. Kato, M. Kaneko, Y. Kumazawa
- Journal Title
  
  Immunopharmacol Immunotoxicol 30
  
  Pages: 747-760
- Data Source
  KAKENHI-PROJECT-20590454
[Journal Article] Interferon-γ independent formation of pulmonary granuloma in mice by injections with trehalose dimycolate (cord factor),lipoarabinomannan and phosphatidylinositol mannosides isolated from Mycobacterium tuberculosis2006
- Author(s)
  Takimoto H.
- Journal Title
  
  Clin.Exp.Immunol 44
  
  Pages: 134-141
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590436
[Journal Article] Interferon-γ independent formation of pulmonary granuloma in mice by injections with trehalose dimycolate (cord factor), lipoarabinomannan and phosphatidylinositol mannosides isolated from Mycobacterium tuberculosis2000
- Author(s)
  Takimoto, H
- Journal Title
  
  Clin. Exp. Immunol 44(1)
  
  Pages: 134-141
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590436
[Journal Article] Suppressive effects of flavonoids quercetin and luteolin on lipid raft accumulation following signal transduction via receptors.
- Author(s)
  Kaneko M, Takimoto H, Seki Y, Kawaguchi K, Kumazawa Y
- Journal Title
  
  Immunopharm Immunotox (掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590436
[Presentation] 結核菌糖脂質trehalose 6,6'-dimicolate(TDM)による肉芽腫形成におけるγδ型T細胞の役割2010
- Author(s)
  齋藤昂良、滝本博明、矢野郁也、態沢義雄、服部雅一
- Organizer
  日本細菌学会
- Place of Presentation
  パシフィコ横浜会議センター(神奈川県)
- Data Source
  KAKENHI-PROJECT-20590453
[Presentation] 結核菌糖脂質trehalose 6, 6'-dimicolate (TDM)による肉芽腫形成におけるγδ型T細胞の役割2010
- Author(s)
  齋藤昂良、滝本博明、矢野郁也、熊沢義雄、服部雅一
- Organizer
  第83回日本細菌学会総会 [日本細菌学雑誌第65巻(1):183]
- Place of Presentation
  横浜
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20590453
[Presentation] ガニアシフコイダンの抗インフルエンザ作用の検討日本薬学会2010
- Author(s)
  滝本博明、今野誠、楳原典光、原耕三、山口徹
- Organizer
  第130年会[ファルマシア46巻(2)付録:197]
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20590454
[Presentation] 結核菌糖脂質trehalose 6, 6'-dimicolate(TDM)による肉芽腫形成におけるγδ型T細胞の役割2010
- Author(s)
  齋藤昂良、滝本博明、矢野郁也、熊沢義雄、服部雅一
- Organizer
  日本細菌学会
- Place of Presentation
  パシフィコ横浜会議センター(神奈川県)
- Data Source
  KAKENHI-PROJECT-20590454
[Presentation] 結核菌糖脂質trehalose 6,6'-dimicolate(TDM)による肉芽腫形成におけるγδ型T細胞の役割2010
- Author(s)
  齋藤昂良、滝本博明、矢野郁也、熊沢義雄、服部雅一
- Organizer
  第83回日本細菌学会総会[日本細菌学雑誌第65巻(1):183]
- Place of Presentation
  横浜
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20590454
[Presentation] 結核菌糖脂質trehalose 6,6'-dimycolate(TDM)による炎症誘導作用2009
- Author(s)
  齋藤昴良、滝本博明、矢野郁也、熊沢義雄
- Organizer
  第82回日本細菌学会総会[日本細菌学雑誌第64巻(1):191]
- Place of Presentation
  名古屋
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-20590454
[Presentation] 結核菌糖脂質trehalose 6, 6'-dimycolate (TDM)による炎症誘導作用2009
- Author(s)
  齋藤昴良、滝本博明、矢野郁也、熊沢義雄
- Organizer
  第82回日本細菌学会総会 [日本細菌学雑誌第64巻(1):191]
- Place of Presentation
  名古屋
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-20590453
[Presentation] 結核菌糖脂質trehalose 6, 6'-dimicolateによる肉芽腫形成におけるIL-17産生γδ型T細胞の役割2009
- Author(s)
  齋藤昂良、滝本博明、矢野郁也、熊沢義雄
- Organizer
  第92回日本細菌学会関東支部総会 [第92回日本細菌学会関東支部総会講演抄録集p.42]
- Place of Presentation
  東京
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-20590453
[Presentation] 結核菌糖脂質trehalose 6, 6'-dimicolateによる肉芽腫形成におけるIL-17産生γδ型T細胞の役割2009
- Author(s)
  齋藤昂良、滝本博明、矢野郁也、熊沢義雄
- Organizer
  第92回日本細菌学会関東支部総会[第92回日本細菌学会関東支部総会講演抄録集p.42]
- Place of Presentation
  東京
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-20590454
[Presentation] 結核菌糖脂質trehalose 6,6'-dimycolate(TDM)による炎症誘導作用2008
- Author(s)
  齋藤昴良、滝本博明、矢野郁也、熊沢義雄
- Organizer
  第38回日本免疫学会総会学術集会[日本免疫学会学術集会記録第38巻:158]
- Place of Presentation
  京都
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-20590454
[Presentation] 組換えモルモットサイトカインと単クローン抗体の作製2008
- Author(s)
  宮崎弘基、滝本博明、熊沢義雄
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  京都
- Year and Date
  2008-03-24
- Data Source
  KAKENHI-PROJECT-18590436
[Presentation] 結核菌糖脂質trehalose 6, 6'-dimycolate (TDM)による炎症誘導作用2008
- Author(s)
  齋藤昴良、滝本博明、矢野郁也、熊沢義雄
- Organizer
  第38回日本免疫学会総会学術集会 [日本免疫学会学術集会記録第38巻:158]
- Place of Presentation
  京都
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-20590453

1. KUMAZAWA Yoshio (30072375)

# of Collaborated Projects: 7 results

# of Collaborated Products: 17 results
2. FUKUDA Kyoichi (90294925)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HIRAKATA Hideki (70181146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KISHIHARA Kenji (80214774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HANAOKA Kazunori (40189577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HASUNUMA Ryoichi (30104566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAKANO Toshiaki (70306588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 安藤高志 (40281191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 藤村響男 (50209087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Takimoto Hiroaki 滝本 博明

滝本 博明 タキモト ヒロアキ

TAKIMOTO Hiroaki 滝本 博明

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Mechanism of granuloma formation by mycobacterial glycolipi dsPrincipal Investigator

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[Journal Article] Potentiation of murine innate immunity by α-galacturonosyl-type glycosphingolipids isolated from Sphingomonas yanoikuyae and S. terrae.2009

Author(s)

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Data Source

[Journal Article] Potentiation of murine innate immunity by alpha-galacturonosyl-type glycosphingolipids isolated from Sphingomonas yanoikuyae and S. terrae.2009

Author(s)

Journal Title

Data Source

[Journal Article] Suppressive effects of the flavonoids quercetin and luteolin on the accumulation of lipid rafts after signal transduction via receptors.2008

Author(s)

Journal Title

Data Source

[Journal Article] Suppressive effects of flavonoids quercetin and luteolin on lipid raft accumulation following signal transduction via receptors.2008

Author(s)

Journal Title

Data Source

[Journal Article] Amelioration of skewed Th1/Th2 balance in tumor-bearing and asthma-induced mice by oral administration of Agaricus blazei extracts.2008

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Data Source

[Journal Article] Amelioration of skewed Th1/Th2 balance in tumor-bearing and asthma-induced mice by oral administration of Agaricus blazei extracts.2008

Author(s)

Journal Title

Data Source

[Journal Article] Interferon-γ independent formation of pulmonary granuloma in mice by injections with trehalose dimycolate (cord factor),lipoarabinomannan and phosphatidylinositol mannosides isolated from Mycobacterium tuberculosis2006

Author(s)

Journal Title

Description

Takimoto Hiroaki 滝本博明

滝本博明タキモトヒロアキ

TAKIMOTO Hiroaki 滝本博明