Watanabe Makino 渡邉マキノ

… Alternative Names

WATANABE Makino 渡邉マキノ

渡邉マキノワタナベマキノ

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Researcher Number	00255655
Other IDs
Affiliation (Current)	2025: 順天堂大学, 薬学部, 准教授 2025: 順天堂大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2012 – 2024: 順天堂大学, 医学部, 准教授 2004 – 2005: 順天堂大学, 医学部, 助手 1995 – 1997: 順天堂大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related / Eating habits / Integrated Nutrition Science / Neurophysiology and muscle physiology / General physiology Except Principal Investigator Basic Section 38050:Food sciences-related / Basic Section 09070:Educational technology-related / Eating habits / General physiology / Integrated Nutrition Science
Keywords	Principal Investigator 心機能 / 脚気衝心 / 脚気 / 突然死 / マグネシウム欠乏 / マグネシウム補充 / ミトコンドリア / 低マグネシウム血症 / 心筋保護 / 虚血再灌流障害 … More / ビタミンＢ１欠乏 / 心不全 / ビタミンB1欠乏 / 低栄養 / ミトコンドリア透過性遷移孔 / Mg補充 / 心エコー / 血管平滑筋収縮機能 / Ca2+感受性 / 貧血 / TRPM7チャネル / ミトコンドリア透過性遷移孔(mPTP) / 心血管機能不全 / Langendorff灌流 / 性差 / 低Mg血症 / 慢性的Mg欠乏 / 蛍光顕微測光法 / パッチクランプ法 / 細胞内カルシウム濃度 / 塩素電流 / 血管内皮細胞 … More Except Principal Investigator 血管トーヌス / 高血圧 / マグネシウム欠乏 / 一酸化窒素 / 脚気 / ビタミンB1欠乏 / 医学教育 / ゲーミフィケーション / 医療系学生 / 保健教育 / 高血圧症 / マグネシウム欠乏症 / 心不全 / 血管平滑筋 / 血管収縮 / prostanoid / prostacyclin / nitric oxide / hydrogen peroxide / superoxide / reperfusion injury / ニトログリセリン / HDL / ロイコトリエン / アルギニン / 低酸素灌流-再酸素化 / アシドーシス / プロスタノイド / プロスタサイクリン / 過酸化水素 / スーパーオキシド / 再灌流障害 / 虚血-再灌流障害 / 一酸化窒素合成酵素 / フコイダン / 血管弛緩反応 / 血管内皮細胞 / 培養心筋 / カリブドトキシン / アパミン / カリウムチャネル / 骨格筋 / 心筋 / 株化筋細胞 Less

Development of an Engaging Health Education Support System through Gamification"
- Principal Investigator
  
  関根美和
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 09070:Educational technology-related
- Research Institution
  Juntendo University
ビタミンB1欠乏時における血管の反応性の変化はマグネシウム欠乏とどう関連するか
- Principal Investigator
  
  家崎貴文
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Juntendo University
Is the cardiac sudden death by chronic magnesium deficiency associated with beriberi heart failure? Varidation from undernutrition.Principal Investigator
- Principal Investigator
  
  渡邉マキノ
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Juntendo University
Elucidation of physiological mechanism(s) of magnesium deficiency-induced hypertension
- Principal Investigator
  
  IESAKI TAKAFUMI
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Juntendo University
Investigation of cause of sudden death associated with hypomagnesemia and examination of usefulness of magnesium replacement therapyPrincipal Investigator
- Principal Investigator
  
  Watanabe Makino
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Juntendo University
Investigation of the mechanism of nitric oxide production by an extract of brown marine algae and its usefulness as a functional food
- Principal Investigator
  
  Iesaki Takafumi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  Juntendo University
Is the cardiovascular dysfunction with hypomagnesemia improved by magnesium supplemental treatment?Principal Investigator
- Principal Investigator
  
  WATANABE Makino
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  Juntendo University
慢性的Mg欠乏マウス心臓における心筋保護効果とMgの関与Principal Investigator
- Principal Investigator
  
  渡邉マキノ
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Juntendo University
Induction of Reperfusion Injury by Endothelium-derived Autacoids
- Principal Investigator
  
  OKADA Takao
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Juntendo University School of Medicine
心臓由来株化細胞におけるイオンチャネルの発現に関する研究
- Principal Investigator
  
  OCHI Rikuo
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Juntendo University
血管内皮細胞のカルシウム依存性塩素電流の活性化機序と細胞内情報伝達に関する研究Principal Investigator
- Principal Investigator
  
  渡邉マキノ
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Juntendo University

All 2023 2022 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] マグネシウム欠乏による心機能低下は脚気衝心に関連するのか2023
- Author(s)
  渡邉マキノ
- Journal Title
  
  Precision Medicine
  
  Volume: 6 Pages: 38-42
- Data Source
  KAKENHI-PROJECT-19K05933
[Journal Article] Chronic magnesium deficiency causes reversible mitochondrial permeability transition pore opening and impairs hypoxia tolerance in the rat heart2022
- Author(s)
  Watanabe Makino、Nakamura Kyoko、Kato Megumi、Okada Takao、Iesaki Takafumi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 148 Issue: 2 Pages: 238-247
- DOI
  10.1016/j.jphs.2021.12.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05933, KAKENHI-PROJECT-17K00879
[Journal Article] Langendorff Perfusion Method as an Ex Vivo Model to Evaluate Heart Function in Rats2018
- Author(s)
  Watanabe Makino、Okada Takao
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 1816 Pages: 107-116
- DOI
  10.1007/978-1-4939-8597-5_8
- ISBN
  9781493985968, 9781493985975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K00846
[Journal Article] 低酸素下における心筋細胞内マグネシウムの維持機構2013
- Author(s)
  華藤恵美、中村京子、家崎貴文、岡田隆夫、代田浩之、渡邉マキノ
- Journal Title
  
  順天堂醫事雑誌
  
  Volume: 59 Pages: 260-266
- NAID
  130004712327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24614015
[Presentation] Elevation of Diastolic Blood Pressure and Reduction of Vascular Contraction in Magnesium Deficient Rat Model.2019
- Author(s)
  Takafumi Iesaki, Makino Watanabe
- Organizer
  29th European Meeting on Hypertension and Cardiovascular Protection
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05933
[Presentation] Functional evaluation of myocardium mitochondria in magnesium deficient rat2018
- Author(s)
  Yuya Ohe, Yuuki Yachida, Ryota Hashimoto, Kyoko Nakamura, Takafumi Iesaki, Makino Watanabe
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-15K00846
[Presentation] Magnesium Deficiency Attenuates Vascular Smooth Muscle Contraction in Rat Aorta2018
- Author(s)
  Takafumi Iesaki, Ryo Kakigi, Makino Watanabe
- Organizer
  Experimental Biology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00846
[Presentation] マグネシウム欠乏ラットにおける血管平滑筋収縮の抑制の機序2017
- Author(s)
  宮内翼、竹田安里彩、渡邉マキノ、岡田隆夫、家崎貴文
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K00846
[Presentation] Magnesium deficiency inhibits both voltage-gated and receptor-operated vascular smooth muscle contraction.2016
- Author(s)
  Yuki Iwamoto, Shigetaka Fukuda, Shinya Fujioka, Makino Watanabe, Takao Okada, Takafumi Iesaki
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-15K00846
[Presentation] 慢性Mg欠乏ラット心臓における低酸素耐性の低下とMg補充効果の検討2015
- Author(s)
  渡邉マキノ、柿木亮、中村京子、華藤恵美、家崎貴文、岡田隆夫
- Organizer
  第25回日本病態生理学会
- Place of Presentation
  愛媛大学城北キャンパス
- Year and Date
  2015-08-01
- Data Source
  KAKENHI-PROJECT-15K00846
[Presentation] Mechanisms of cardioprotective effects of high concentration of magnesium on hypoxia/reoxygenation injury in chronic magnesium deficient rat heart are differ from normal rat heart2014
- Author(s)
  Makino Watanabe, Ryo Kakigi, Takafumi Iesaki, Takao Okada
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学郡元キャンパス
- Data Source
  KAKENHI-PROJECT-24614015
[Presentation] Mechanisms of cardioprotective effects of high concentration of magnesium on hypoxia/reoxygenation injury in chronic magnesium deficient rat heart are differ from normal rat heart2014
- Author(s)
  Makino Watanabe, Kyoko Nakamura, Megumi Kato, Ryo Kakigi, Takafumi Iesaki, Takao Okada
- Organizer
  Experimental Biology 2014
- Place of Presentation
  San Diego Convention Center
- Data Source
  KAKENHI-PROJECT-24614015
[Presentation] Magnesium Influx Pathway in Cardiomyocytes Under Hypoxic Condition2013
- Author(s)
  Megumi Kato, Kyoko Nakamura, Takafumi Iesaki, Takao Okada, Hiroyuki Daida, Makino Watanabe
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-24614015
[Presentation] Mechanisms of cardioprotective effects of high magnesium on hypoxia/reoxygenation injury in chronic magnesium deficient rat heart are differ from normal rat heart
- Author(s)
  Makino Watanabe, Kyoko Nakamura, Megumi Kato, Ryo Kakigi, Takafumi Iesaki, Takao Okada
- Organizer
  Experimental Biology 2014
- Place of Presentation
  San Diego Convention Center
- Year and Date
  2014-04-26 – 2014-04-30
- Data Source
  KAKENHI-PROJECT-24614015

1. IESAKI Takafumi (10348956)

# of Collaborated Projects: 6 results

# of Collaborated Products: 12 results
2. OCHI Rikuo (10049025)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Kakigi Ryo (70614931)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 中村京子 (90578858)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. Hashimoto Ryota (60433786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OKADA Takao (00146763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 関根美和 (10398670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 西崎祐史 (60743888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 野中里紗 (90614248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Watanabe Makino 渡邉 マキノ

WATANABE Makino 渡邉 マキノ

渡邉 マキノ ワタナベ マキノ

Research Projects

Research Products

Co-Researchers

Development of an Engaging Health Education Support System through Gamification"

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ビタミンB1欠乏時における血管の反応性の変化はマグネシウム欠乏とどう関連するか

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Is the cardiac sudden death by chronic magnesium deficiency associated with beriberi heart failure? Varidation from undernutrition.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of physiological mechanism(s) of magnesium deficiency-induced hypertension

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of cause of sudden death associated with hypomagnesemia and examination of usefulness of magnesium replacement therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of the mechanism of nitric oxide production by an extract of brown marine algae and its usefulness as a functional food

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Is the cardiovascular dysfunction with hypomagnesemia improved by magnesium supplemental treatment?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

慢性的Mg欠乏マウス心臓における心筋保護効果とMgの関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Induction of Reperfusion Injury by Endothelium-derived Autacoids

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心臓由来株化細胞におけるイオンチャネルの発現に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Institution

血管内皮細胞のカルシウム依存性塩素電流の活性化機序と細胞内情報伝達に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] マグネシウム欠乏による心機能低下は脚気衝心に関連するのか2023

Author(s)

Journal Title

Data Source

[Journal Article] Chronic magnesium deficiency causes reversible mitochondrial permeability transition pore opening and impairs hypoxia tolerance in the rat heart2022

Author(s)

Journal Title

DOI

Data Source

Watanabe Makino 渡邉マキノ

WATANABE Makino 渡邉マキノ

渡邉マキノワタナベマキノ