Kakigi Ryo 柿木亮

… Alternative Names

Researcher Number	70614931
Other IDs
Affiliation (Current)	2022: 順天堂大学, スポーツ健康科学部, 非常勤助教
Affiliation (based on the past Project Information) *help	2019 – 2021: 順天堂大学, スポーツ健康科学部, 非常勤助教 2016 – 2018: 順天堂大学, 医学部, 助教 2012 – 2014: 順天堂大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Sports science / Sports science / Basic Section 59020:Sports sciences-related Except Principal Investigator Integrated Nutrition Science / Eating habits / Applied health science / Basic Section 59020:Sports sciences-related / Basic Section 59010:Rehabilitation science-related
Keywords	Principal Investigator 細胞内シグナル伝達 / 筋肥大 / タンパク質合成 / 筋タンパク質合成 / サルコペニア / 筋萎縮 / 筋収縮様式 / 筋線維組成 / レジスタンス運動 / 筋線維タイプ … More Except Principal Investigator サルコペニア / 筋萎縮 / 血管内皮細胞 / 一酸化窒素 / 血管弛緩反応 / フコイダン / 一酸化窒素合成酵素 / 虚血-再灌流障害 / マグネシウム欠乏 / 高血圧 / 血管収縮 / 血管平滑筋 / マグネシウム欠乏症 / 高血圧症 / 血管トーヌス / 骨格筋 / 温熱刺激 / サルコペニア肥満 / 肥満 / 加齢 / JNK / 老齢 / 糖代謝 / 高脂肪食 / 性差 / アンジオテンシンII受容体 / トレーナビリティ / 運動療法 / 心不全 / 心室性不整脈 Less

The construction of exercise therapy in familial DCM model mice
- Principal Investigator
  
  杉原匡美
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Juntendo University
骨格筋適応の性差を司るアンジオテンシン受容体制御機構の解明
- Principal Investigator
  
  吉原利典
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Juntendo University
ビタミンD不足はサルコペニア進行の増悪因子なのか？Principal Investigator
- Principal Investigator
  
  柿木亮
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Juntendo University
マグネシウム欠乏による高血圧発症の生理学的メカニズムの解明
- Principal Investigator
  
  家崎貴文
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Juntendo University
Mechanisms underlying heat stress-induced skeletal muscle adaptation in prevention of sarcopeniaPrincipal Investigator
- Principal Investigator
  
  Kakigi Ryo
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Sports science
- Research Institution
  Juntendo University
Effect of heat stress on body fat mass and muscle mass in mice with sarcopenia obesity
- Principal Investigator
  
  Goto Ayumi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Applied health science
- Research Institution
  Juntendo University
Investigation of the mechanism of nitric oxide production by an extract of brown marine algae and its usefulness as a functional food
- Principal Investigator
  
  Iesaki Takafumi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  Juntendo University
Effect of muscle contraction mode on intracellular signaling-related muscle hypertrophyPrincipal Investigator
- Principal Investigator
  
  KAKIGI RYO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Sports science
- Research Institution
  Juntendo University

All 2021 2019 2018 2017 2016 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Long-term physical inactivity exacerbates hindlimb unloading-induced muscle atrophy in young rat soleus muscle2021
- Author(s)
  Yoshihara Toshinori、Natsume Toshiharu、Tsuzuki Takamasa、Chang Shuo-Wen、Kakigi Ryo、Machida Shuichi、Sugiura Takao、Naito Hisashi
- Journal Title
  
  Journal of Applied Physiology
  
  Volume: 130 Pages: 1214-1225
- DOI
  10.1152/japplphysiol.00494.2020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11526
[Journal Article] Age-related changes in histone modification in rat gastrocnemius muscle2019
- Author(s)
  Yoshihara T, Machida S, Tsuzuki T, Kakigi R, Chang SW, Sugiura T, Naito H.
- Journal Title
  
  Experimental Gerontology
  
  Volume: 125 Pages: 110658-110658
- DOI
  10.1016/j.exger.2019.110658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01765, KAKENHI-PROJECT-19K11526, KAKENHI-PROJECT-16H03205
[Journal Article] Sex-specific differences in rat soleus muscle signaling pathway responses to a bout of horizontal and downhill running2019
- Author(s)
  Yoshihara T, Chang SW, Tsuzuki T, Natsume T, Kakigi R, Sugiura T, Naito H.
- Journal Title
  
  Journal of Physiology and Biochemistry
  
  Volume: 75(4) Pages: 585-595
- DOI
  10.1007/s13105-019-00712-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01765, KAKENHI-PROJECT-16K16565
[Journal Article] Effect of a combination of astaxanthin supplementation, heat stress, and intermittent reloading on satellite cells during disuse muscle atrophy.2018
- Author(s)
  Toshinori Yoshihara, Takao Sugiura, Nobuyuki Miyaji, Yuki Yamamoto, Tsubasa Shibaguchi, Ryo Kakigi, Hisashi Naito, Katsumasa Goto, Daijiro Ohmori, Toshitada Yoshioka
- Journal Title
  
  Journal of Zhejiang University-SCIENCE B.
  
  Volume: N/A Pages: 844-852
- DOI
  10.1631/jzus.b1800076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01765, KAKENHI-PROJECT-17K01762, KAKENHI-PROJECT-16K16565, KAKENHI-PROJECT-18H03160
[Journal Article] Body temperature elevation during exercise is essential for activating the Akt signaling pathway in the skeletal muscle of type 2 diabetic rats2018
- Author(s)
  Tsuzuki Takamasa、Yoshihara Toshinori、Ichinoseki-Sekine Noriko、Kakigi Ryo、Takamine Yuri、Kobayashi Hiroyuki、Naito Hisashi
- Journal Title
  
  PLOS ONE
  
  Volume: 13
- DOI
  10.1371/journal.pone.0205456
- NAID
  120007133689
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K16565
[Journal Article] Heat stress-induced phosphorylation of FoxO3a signaling in rat skeletal muscle.2016
- Author(s)
  Yoshihara T, Kobayashi H, Kakigi R, Sugiura T, Naito H.
- Journal Title
  
  Acta Physiol (Oxf).
  
  Volume: 218(3) Pages: 178-187
- DOI
  10.1111/apha.12735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26506021, KAKENHI-PROJECT-16K16565
[Journal Article] Whey protein intake after resistance exercise activates mTOR signaling in a dose-dependent manner in human skeletal muscle.2014
- Author(s)
  Kakigi R, Yoshihara T, Ozaki H, Ogura Y, Ichinoseki-Sekine N, Kobayashi H, Naito H
- Journal Title
  
  Eur J Appl Physiol.
  
  Volume: 114 Pages: 735-42
- DOI
  10.1007/s00421-013-2812-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10802, KAKENHI-PROJECT-24700703
[Journal Article] Effects of walking combined with restricted leg blood flow on mTOR and MAPK signalling in young men.2014
- Author(s)
  Ozaki H, Kakigi R, Kobayashi H, Loenneke JP, Abe T, Naito H
- Journal Title
  
  Acta Physiol (Oxf).
  
  Volume: (印刷中) Pages: 97-106
- DOI
  10.1111/apha.12243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10802, KAKENHI-PROJECT-24700703
[Presentation] High-fat diet augments muscle atrophy by changes of muscle atrophy-related genes in mice2018
- Author(s)
  Goto A, Tsuzuki T, Yoshihara T, Furuichi S, Tsukioka K, Kakigi R, Naito H
- Organizer
  Experimental Biology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07182
[Presentation] 温熱刺激はサルコペニア肥満の新規治療法となり得るか？2018
- Author(s)
  後藤亜由美, 柿木亮, 吉原利典, 松本綾子, 都築孝允, 古市真也, 月岡恵惟, 内藤久士
- Organizer
  第26回日本物理療法学会学術大会
- Data Source
  KAKENHI-PROJECT-16K16565
[Presentation] Effects of heat stress treatment and leucine supplementation on age-related muscle loss in mice2018
- Author(s)
  Kakigi R, Goto A, Yoshihara T, Tsuzuki T, Naito H
- Organizer
  Experimental Biology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16565
[Presentation] Acute heat stress under fed state stimulates muscle protein synthesis in mouse soleus muscle2018
- Author(s)
  Kakigi R, Yoshihara T, Goto A, Naito H
- Organizer
  2018 ACSM conference on integrative physiology of exercise
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16565
[Presentation] Effects of heat stress treatment and leucine supplementation on agerelated muscle loss in mice.2018
- Author(s)
  Kakigi R, Goto A, Yoshihara T, Tsuzuki T, Naito H
- Organizer
  Experimental Biology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07182
[Presentation] 肥満が廃用性筋萎縮に伴う筋萎縮関連遺伝子の発現に及ぼす影響2017
- Author(s)
  後藤亜由美、都築孝允、吉原利典、柿木亮、古市真也、月岡惠惟、内藤久士
- Organizer
  第72回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-16H07182
[Presentation] Effects of a bout of downhill running on skeletal muscle function and Ca2+ handling in mouse extensor digitorum longus muscle2017
- Author(s)
  Kakigi R, Nakamura K, Eshima H, Yoshihara T, Naito H
- Organizer
  The 3rd congress, International Academy of Sportology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16565
[Presentation] 温熱刺激とロイシン摂取の組み合わせが高齢マウスの筋量および筋機能に及ぼす影響2017
- Author(s)
  柿木亮、後藤亜由美、吉原利典、都築孝允、内藤久士
- Organizer
  第72回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-16H07182
[Presentation] Effect of acute immobilization on the expression levels of atrophy-related ubiquitin ligase in mice fed a high-fat diet.2017
- Author(s)
  Goto A, Tsuzuki T, Yoshihara T, Furuichi S, Tsukioka K, Zhi L, Kakigi R, Naito H.
- Organizer
  The 3rd Congress, International Academy of Sportology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07182
[Presentation] 温熱刺激とロイシン摂取の組み合わせが高齢マウスの筋量および筋機能に及ぼす影響2017
- Author(s)
  柿木亮、後藤亜由美、吉原利典、都築孝允、内藤久士
- Organizer
  第72回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-16K16565
[Presentation] 男性短距離走者の骨格筋におけるACTN3タンパク質発現量と筋線維組成2013
- Author(s)
  中村智洋、柿木亮、関根紀子、小林裕幸、佐久間和彦、内藤久士
- Organizer
  第58回日本体力医学会大会
- Place of Presentation
  教育会館（東京）、日本
- Data Source
  KAKENHI-PROJECT-24700703
[Presentation] Submaximal cycling exercise stimulates mTOR signaling pathway in human skeletal muscle.2013
- Author(s)
  Kakigi R, Naito H, Yoshihara T, Ozaki H, Kobayashi H, Okada T.
- Organizer
  Experimental biology 2013
- Place of Presentation
  Boston, USA.
- Data Source
  KAKENHI-PROJECT-24700703
[Presentation] ラット骨格筋の過負荷によるmTORシグナル伝達経路の活性化に持久性運動における強度の違いが及ぼす影響2013
- Author(s)
  尾崎隼雄、柿木亮、内藤久士
- Organizer
  第58回日本体力医学会大会
- Place of Presentation
  教育会館（東京）、日本
- Data Source
  KAKENHI-PROJECT-24700703
[Presentation] 最大下自転車運動によるヒト骨格筋Akt/mTORシグナル伝達の経時変化2013
- Author(s)
  柿木亮、内藤久士、吉原利典、尾崎隼朗、都築孝允、小林裕幸、岡田隆夫
- Organizer
  第58回日本体力医学会大会
- Place of Presentation
  教育会館（東京）、日本
- Data Source
  KAKENHI-PROJECT-24700703
[Presentation] Whey protein ingestion after exercise decreases LC3-II expression in human muscle.2012
- Author(s)
  Kakigi R.
- Organizer
  15th International Biochemistry of Exercise Conference.
- Place of Presentation
  Stockholm, Sweden.
- Data Source
  KAKENHI-PROJECT-24700703
[Presentation] Effects of whey peptide ingestion after resistance exercise on mTOR signaling in human skeletal muscle.2012
- Author(s)
  Kakigi R.
- Organizer
  The American College of Sports Medicine 59th Annual Meeting.
- Place of Presentation
  Sanfrancisco, USA.
- Data Source
  KAKENHI-PROJECT-24700703
[Presentation] Eccentric muscle contraction stimulates mTOR signaling in human skeletal muscle
- Author(s)
  Kakigi R, Naito H, Yoshihara T, Ichinoseki-Sekine N, Okada T.
- Organizer
  The 92nd Annual Meeting of The Physiological Society of Japan
- Place of Presentation
  Kobe, Japan
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-24700703
[Presentation] 伸張性収縮運動によるヒト骨格筋mTORシグナルの増加は鍛練度によって異なる
- Author(s)
  柿木亮、内藤久士、吉原利典、坂本彰宏、中村智洋、小林裕幸、岡田隆夫
- Organizer
  第69回日本体力医学会大会
- Place of Presentation
  長﨑、日本
- Year and Date
  2014-09-19 – 2014-09-21
- Data Source
  KAKENHI-PROJECT-24700703

1. Iesaki Takafumi (10348956)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. NAITO Hisashi (70188861)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. YOSHIHARA Toshinori (20722888)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. 渡邉マキノ (00255655)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Hashimoto Ryota (60433786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Goto Ayumi (20780969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. TSUZUKI Takamasa (20780068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. 町田修一 (40421226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 杉原匡美 (80648163)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 村山尚 (10230012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 呉林なごみ (50133335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 後藤勝正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 吉岡利忠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kakigi Ryo 柿木 亮

KAKIGI RYO 柿木 亮

Research Projects

Research Products

Co-Researchers

The construction of exercise therapy in familial DCM model mice

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

骨格筋適応の性差を司るアンジオテンシン受容体制御機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ビタミンD不足はサルコペニア進行の増悪因子なのか？Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マグネシウム欠乏による高血圧発症の生理学的メカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms underlying heat stress-induced skeletal muscle adaptation in prevention of sarcopeniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of heat stress on body fat mass and muscle mass in mice with sarcopenia obesity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of the mechanism of nitric oxide production by an extract of brown marine algae and its usefulness as a functional food

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of muscle contraction mode on intracellular signaling-related muscle hypertrophyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Long-term physical inactivity exacerbates hindlimb unloading-induced muscle atrophy in young rat soleus muscle2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Age-related changes in histone modification in rat gastrocnemius muscle2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sex-specific differences in rat soleus muscle signaling pathway responses to a bout of horizontal and downhill running2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of a combination of astaxanthin supplementation, heat stress, and intermittent reloading on satellite cells during disuse muscle atrophy.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Body temperature elevation during exercise is essential for activating the Akt signaling pathway in the skeletal muscle of type 2 diabetic rats2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Heat stress-induced phosphorylation of FoxO3a signaling in rat skeletal muscle.2016

Kakigi Ryo 柿木亮

KAKIGI RYO 柿木亮

[Presentation] Effects of heat stress treatment and leucine supplementation on agerelated muscle loss in mice.2018