HONGO Kenichi 本郷賢一

… Alternative Names

本郷賢一ホンゴウケンイチ

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Researcher Number	00256447
Other IDs
Affiliation (Current)	2025: 東京慈恵会医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2014: 東京慈恵会医科大学, 医学部, 教授 2007 – 2014: Jikei University School of Medicine, 医学部, 准教授 2006: Jikei University, School of Medicine, Associate Professor, 医学部, 助教授 2001 – 2006: 東京慈恵会医科大学, 医学部, 講師 2003: Jikei University, School of Medicine, Lecturer, 医学部, 講師 … More 1999: The Jikei University School of Medicine, Department of Medicine, Lecturer, 医学部, 講師 1998: 東京慈恵会医科大学, 内科学講座・第4, 講師 1997: 東京慈恵会医科大学, 医学部, 講師 1997: 東京慈恵会医科大学, 医学部・内科学講座第4, 講師 1996: 東京慈恵会医科大学, 医学部・内科4, 助手 Less
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / General physiology Except Principal Investigator General physiology / Neurophysiology and muscle physiology / Pediatrics / Science and Engineering / Neurophysiology and muscle physiology / Circulatory organs internal medicine
Keywords	Principal Investigator 細胞内カルシウム / 心筋収縮 / SERCA / Acidosis / Diastolic dysfunction / Intracellular calcium concentration / Mouse heart / 心不全 / アンジオテンシンII / 細胞内カルシウム濃度 … More / 筋小胞体Caポンプ / アシドーシス / 拡張障害 / 細胞内Ca濃度 / マウス心筋 / 遺伝子改変 / リン酸化調節 / 筋小胞体機能 / 細胞内Ca動態 / 心臓病態学 / カリウム電流 / 虚血 / カルシウム感受性 / カルシウム電流 / 細胞内ナトリウム … More Except Principal Investigator 心筋 / マウス / 筋小胞体 / 細胞内Ca^<2+> / トロポニン / Ca^<2+> / mouse / Ca^<2+>トランジェント / SERCA2a / 細胞内Ca / 拡張型心筋症 / Ca感受性 / Ca^<2+>感受性 / アンギオテンシン / カルシウム / ラット / CaMKII / Ca^<2+> transients / cardiac muscle / saponin / skinned preparation / sarcolipin / sarcoplasmic reticulum / 筋小胞体Caポンプ / ウエスタンブロッティン / サポニン / スキンド標本 / サルコリピン / acidosis / isoprenaline / Ca^<2+> transient / ryanodine receptor type2 / myocardium / intracellular Ca^<2+> / エクオリン / 遺伝子非改変マウス / 収縮蛋白系 / SERCA / Caポンプ / 張力 / 細胞内Ca transient / マウス心室筋 / Ca^<2+>transient / β受容体 / エクオリン法 / antiport / NaィイD1+ィエD1-MgィイD12+ィエD1 exchange / NaィイD1+ィエD1-CaィイD12+ィエD1 exchange / Cardiac muscle / Smooth muscle / Transporter / Sodium / Magnesium / Na-Mg交換輸送 / 細胞内Na濃度 / 平滑筋細胞 / 盲腸紐 / モルモット / 蛍光Mg指示薬 / Na-Ca交換輸送 / 細胞内Ca濃度 / 細胞内Mg濃度 / 平滑筋 / Na-Mg交換 / Na-Ca交換 / 交換輸送 / 膜輸送 / ナトリウム / マグネシウム / Autophagy / bisoprolol / 肺動脈絞扼術 / 右室肥大 / ミトコンドリア / 肺動脈 / 右心不全 / 生体分子 / 生物物理学 / 分子心臓学 / 筋肉生理学 / 分子・細胞生理学 / バイオイメージング / 医用画像・バイオイメージング / 生体情報・計測 / ナノバイオシステム / 生物物理 / 再生医学 / 生理学 / 分子イメージング / 循環器・高血圧 / 細胞・組織 / ナノバイオ / RAA系 / 線維化 / 細胞内Ca2^<2+> / Ca 感受性 / 心エコー / レニン・アンギオテンシン系 / Ca transient / DCM / アンギオテンシンII / Caトランジェント / アンギオテンシンII受容体 / トロポニンT / KN-93 / α受容体 / 生理活性 / ETB受容体 / プロテインキナーゼ / ETA受容体 / パッチクランプ法 / プロテインキナーゼC / シグナル伝達 / カルシウム電流 / エンドセリン Less

Establishment of RV heart failure treatment associated brain blood flow
- Principal Investigator
  
  URASHIMA Takashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Jikei University School of Medicine
Elucidation of the heart's functions by in vivo nano-imaging
- Principal Investigator
  
  Norio Fukuda
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Jikei University School of Medicine
Molecular mechanisms of an improvement in prognosis in the mouse model of dilated cardiomyopathy treated by inhibition of the RAA system
- Principal Investigator
  
  KURIHARA Satoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Jikei University School of Medicine
Molecular mechanism of contractile dysfunction and the alteration of intracellular Ca^<2+> handling caused by mutation of cardiac troponin T
- Principal Investigator
  
  KURIHARA Satoshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Jikei University School of Medicine
Role of selective modulation of sarcoplasmic reticulum function on cardiac contraction during ischemia.Principal Investigator
- Principal Investigator
  
  HONGO Kenichi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Jikei University School of Medicine
Coupling of protein kinase C and Ca/calmodulin dependent protein kinase II in cardiac muscle
- Principal Investigator
  
  KOMUKAI Kimiaki
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Jikei University School of Medicine
Molecular mechanisms of Ca^<2+> uptake by sarcolipin in cardiac sarcoplasmic reticulum.
- Principal Investigator
  
  KURIHARA Satoshi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Jikei University School of Medicine
Mechanism of diastolic dysfunction in pressure-overloaded mouse heartPrincipal Investigator
- Principal Investigator
  
  HONGO Kenichi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The Jikei University School of Medicine
Intracellular Ca^<2+> regulation in the myocardium with ryanodine receptor type 2(+/-) heterozygous mouse
- Principal Investigator
  
  KURIHARA Satoshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Jikei University School of Medicine
虚血時心筋収縮力低下に対する長さ依存性代償機転の関与とその調節機序Principal Investigator
- Principal Investigator
  
  本郷賢一
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Jikei University School of Medicine
Identification and quantitative analysis of the cell membrane MgィイD1[2+]ィエD1 transporter in cardiac and smooth muscles.
- Principal Investigator
  
  KONISHI Masato
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Medical University
  Jikei University School of Medicine
カーボンファイバー法によるラット単離心室筋細胞の伸長・短縮Principal Investigator
- Principal Investigator
  
  本郷賢一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Jikei University School of Medicine

All 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Alpha_1-adrenenoceptor stimulation inhibits cardiac excitation-contraction coupling through tyrosine phosphorylation of beta_1-adrenoceptor2013
- Author(s)
  O-Uchi J, Komukai K, Kusakari Y, Morimoto S, Kawai M, Jhun BS, Hurst S, Hongo K, Sheu SS, Kurihara S
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 433(2) Issue: 2 Pages: 188-93
- DOI
  10.1016/j.bbrc.2013.02.072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300130, KAKENHI-PUBLICLY-23136515
[Journal Article] Depressed Frank-Starling mechanism in the left ventricular muscle of the knock-in mouse model of dilated cardiomyopathy with troponin T deletion mutation ΔK2102013
- Author(s)
  Inoue T, Kobirumaki-Shimozawa F, Kagemoto T, Fujii T, Terui T, Kusakari Y, Hongo K, Morimoto S, Ohtsuki I, Hashimoto K, Fukuda N
- Journal Title
  
  J Mol Cell Cardiol.
  
  Volume: 63 Pages: 69-78
- DOI
  10.1016/j.yjmcc.2013.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107003, KAKENHI-PROJECT-23300146, KAKENHI-PROJECT-23650274, KAKENHI-PROJECT-23659116, KAKENHI-PUBLICLY-25136719
[Journal Article] カルシウム拮抗薬の心保護作用2010
- Author(s)
  本郷賢一
- Journal Title
  
  CLINICAL CALCIUM 20
  
  Pages: 89-93
- Data Source
  KAKENHI-PROJECT-19590833
[Journal Article] Role of Ca2+/calmodulin-dependent protein kinase II in the regulation of the cardiac L-type Ca2+ current during endothelin-1 stimulation.2010
- Author(s)
  Komukai K, O-Uchi J, Morimoto S, Kawai M, Hongo K, Yoshimura M, Kurihara S
- Journal Title
  
  Am J Physiol Heart Circ Physiol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590833
[Journal Article] Caと平滑筋収縮の関係(CaシグナルとRhoキナーゼ系を含めて)2010
- Author(s)
  本郷賢一, 他
- Journal Title
  
  Modern Physician 30
  
  Pages: 343-5
- Data Source
  KAKENHI-PROJECT-18590789
[Journal Article] Role of Ca^/calmodulin-dependent protein kinase II in the regulation of the cardiac L-type Ca^current during endothelin-1 stimulation2010
- Author(s)
  Komukai K, O-Uchi J, Morimoto S, Kawai M, Hongo K, Yoshimura M, Kurihara S
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 298(6) Issue: 6 Pages: H1902-H1907
- DOI
  10.1152/ajpheart.01141.2009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300130
[Journal Article] Caと平滑筋収縮の関係(CaシグナルとRhoキナーゼ系を含めて)2010
- Author(s)
  本郷賢一
- Journal Title
  
  Modern Physician 30巻
  
  Pages: 343-345
- Data Source
  KAKENHI-PROJECT-19590833
[Journal Article] Role of Ca^<2+>/calmodulin-dependent protein kinase II in the regulation of the cardiac L-type Ca^<2+> current during endothelin-1 stimulation.2010
- Author(s)
  Komukai K, O-Uchi J, Morimoto S, Kawai M, Hongo K, Yoshimura M, Kurihara S.
- Journal Title
  
  Am J Physiol Heart Circ Physiol.
  
  Volume: 298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300130
[Journal Article] Caと平滑筋収縮の関係(CaシグナルとRhoキナーゼ系を含めて)2010
- Author(s)
  本郷賢一
- Journal Title
  
  Modern Physician 30
  
  Pages: 343-345
- Data Source
  KAKENHI-PROJECT-19590833
[Journal Article] Protein kinase A-dependent phosphorylation of ryanodine receptors increases Ca2+ leak in mouse heart.2009
- Author(s)
  Morimoto S, O-Uchi J, Kawai M, Hoshina T, Kusakari Y, Komukai K, Sasaki H, Hongo K, Kurihara S
- Journal Title
  
  Biochem Biophys Res Commun 390(1)
  
  Pages: 87-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590833
[Journal Article] Protein kinase A-dependent phosphorylation of ryanodine receptors increase Ca(2+) leak in mouse heart.2009
- Author(s)
  Morimoto S, O-Uchi J, Kawai M, Hosh T, Kusakari Y, Komukai K, Sasaki H, Hongo K, Kurihara S.
- Journal Title
  
  Biochem Biophys Res Commun 390
  
  Pages: 87-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590789
[Journal Article] Protein kinase A-dependent phosphorylation of ryanodine receptors increases Ca^<2+> leak in mouse heart.2009
- Author(s)
  Morimoto S, O-Uchi J, kawai M, Hoshina T, Kusakari Y, Komukai K, Sasaki H, Hongo K, Kurihara S
- Journal Title
  
  BBRC 390
  
  Pages: 87-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500357
[Journal Article] Protein kinase A-dependent phosphorylation of ryanodine receptors increases Ca2+ leak in mouse heart2009
- Author(s)
  Morimoto S, O-Uchi J, Kawai M, Hoshina T, Kusakari Y, Komukai K, Sasaki H, Hongo K, Kurihara S
- Journal Title
  
  BBRC 390
  
  Pages: 87-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500357
[Journal Article] Telmisartan predominantly suppresses cardiac fibrosis, rather than hypertrophy2009
- Author(s)
  Kawai M, Hongo K, Komukai K, Morimoto S, Nagai M, Seki S, Taniguchi I, Mochizuki S, Yoshimura M.
- Journal Title
  
  in renovascular hypertensive rats. Hypertens Res 32
  
  Pages: 604-610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590789
[Journal Article] Telmisartan predominantly suppresses cardiac fibrosis, rather than hypertrophy, in renovascular hypertensive rats2009
- Author(s)
  Kawai M, Hongo K, Komukai K, Morimoto S, Nagai M, Seki S, Taniguchi I Mochizuki S. Yoshimura M.
- Journal Title
  
  Hypertension Res 32
  
  Pages: 604-10
- NAID
  10025164290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590789
[Journal Article] Telmisartan predominantly suppresses cardiac fibrosis, rather than hypertrophy2009
- Author(s)
  Kawai M, Hongo K, Komukai K, Morimoto S, Nagai M, Seki S, Taniguchi I, Mochizuki S, Yoshimura M
- Journal Title
  
  in renovascular hypertensive rats. Hypertens Res 32(7)
  
  Pages: 604-610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590833
[Journal Article] Inhibition of the renin-angiotensin system prevents re-hospitalization of heart failure patients with preserved ejection fraction.2008
- Author(s)
  Komukai K, Yagi H, Ogawa T, Date T, Morimoto S, Kawai M, Hongo K, Taniguchi I, Yoshimura M
- Journal Title
  
  Circ J 72(12)
  
  Pages: 2004-2008
- NAID
  110006987355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590833
[Journal Article] 心血管疾患のバイオマーカー最前線2008
- Author(s)
  本郷賢一
- Journal Title
  
  日本内科学会雑誌 137
- Data Source
  KAKENHI-PROJECT-19590833
[Journal Article] Decreased renal function as an independent predictor of re-hospitalization for congestive heart failure.2008
- Author(s)
  Komukai K, Ogawa T, Yagi H, Date T, Sakamoto H, Kanzaki Y, Shibayama K, Hashimoto K, Inada K, Minai K, Ogawa K, Kosuga T, Kawai M, Hongo K, Taniguchi I, Yoshimura M
- Journal Title
  
  Circ J 72(7)
  
  Pages: 1152-1157
- NAID
  110006792071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590833
[Journal Article] Inhibition of the renin-angiotensin system prevents re-hospitalization in heart failure patients with preserved ejection fraction2008
- Author(s)
  Komukai K, Yagi H, Ogawa T, Date T, Morimoto S, Kawai M, Hongo K, Taniguchi I, Yoshimura M.
- Journal Title
  
  Circ J 72
  
  Pages: 2004-8
- NAID
  110006987355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590789
[Journal Article] Interaction of alphal-adrenoceptor subtypes with different G proteins induces opposite effects on cardiac L-type Ca^<2+>channel.2008
- Author(s)
  O-Uchi J, Sasaki H, Morimoto S, Kusakari Y, Shinji H, Obata T, Hongo K, Komukai K, Kurihara S
- Journal Title
  
  Circ Res. 102(11)
  
  Pages: 1378-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500357
[Journal Article] interaction of alpha1-adrenoceptor subtypes with different G proteins induces opposite effects on cardiac L-type Ca^<2+> channel2008
- Author(s)
  O-Uchi J, Sasaki H, Morimoto S, Kusakari Y, Shinji H, Obata T, Hongo K, Komukai K, Kurihara S.
- Journal Title
  
  Circ Res 102
  
  Pages: 1378-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590789
[Journal Article] 心血管疾患のバイオマーカー最前線2008
- Author(s)
  本郷賢一、吉村道博
- Journal Title
  
  日本内科学会雑誌 137巻
- Data Source
  KAKENHI-PROJECT-19590833
[Journal Article] Interaction of alpha1-adrenoceptor subtypes with different G proteins induces opposite effects on cardiac L-type Ca2 channel2008
- Author(s)
  O-Uchi J, Sasaki H, Morimoto S, Kusakari Y, Shinji H, Obata T, Hongo K, Komukai K, Kurihara S
- Journal Title
  
  Circ Res 102(11)
  
  Pages: 1378-1388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500357
[Journal Article] Interaction of alpha1-adrenoceptor subtypes with different G proteins induces opposite effects on cardiac L-type Ca2+ channel.2008
- Author(s)
  O-Uchi J, Sasaki H, Morimoto S, Kusakari Y, Shinji H, Obata T, Hongo K, Komukai K, Kurihara S
- Journal Title
  
  Circ Res 102(11)
  
  Pages: 1378-1388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590833
[Journal Article] Interaction of {alpha}1-Adrenoceptor Subtypes With Different G Proteins Induces Opposite Effects on Cardiac L-type Ca(2+) Channel.2008
- Author(s)
  O-Uchi J, Sasaki H, Morimoto S, Kusakari Y, Shinji H, Obata T, Hongo K, Komukai K, Kurihara S.
- Journal Title
  
  Circ Res 102
  
  Pages: 1378-1388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590789
[Journal Article] Renal insufficiency is related to painless myocardial infarction.2007
- Author(s)
  Komukai K, Ogawa T, Yagi H, Date T, Suzuki K, Sakamoto H, Miyazaki H, Takatsuka H, Shibayama K, Ogawa K, Kanzaki Y, Kosuga T, Kawai M, Hongo K, Yoshida S, Taniguchi I, Mochizuki S
- Journal Title
  
  Circ J 71(9)
  
  Pages: 1366-1369
- NAID
  110006399679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590833
[Journal Article] Use of the Ca-shortening curve to estimate the myofilament responsiveness to Ca2+ in tetanized rat ventricular myocytes.2006
- Author(s)
  Kusakari Y, Hongo K, Kawai M, Konishi M, Kurihara S.
- Journal Title
  
  J Physiol Sci 56
  
  Pages: 219-226
- NAID
  10020331576
- Data Source
  KAKENHI-PROJECT-18590789
[Journal Article] Intracellular mechanism of the negative inotropic effect induced by alpha1-adrenoceptor stimulation in mouse myocardium.2006
- Author(s)
  Hirano S, Kusakari Y, O-Uchi J, Morimoto S, Kawai M, Hongo K, Kurihara S.
- Journal Title
  
  J Physiol Sci 56
  
  Pages: 297-304
- NAID
  130004466859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590789
[Journal Article] Role of Ca2+/calmodulin-dependent protein kinase II in the regulation of the cardiac L-type Ca2+ current durinendothelin-1 stimulation.
- Author(s)
  Komukai K, O-Uchi J, Morimoto S, KaM, Hongo K, Yoshimura M, Kurihara S.
- Journal Title
  
  Am Physiol Heart Circ Physiol 2010 press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590789
[Journal Article] カルシウム拮抗薬の心保護作用
- Author(s)
  本郷賢一、吉村道博
- Journal Title
  
  CLINICAL CALCIUM 20巻
  
  Pages: 89-93
- Data Source
  KAKENHI-PROJECT-19590833
[Presentation] Depressed length-dependent activation in left ventricular muscle of the knock-in mouse model of dilated cardiomyopathy with troponin T deletion mutation K2102013
- Author(s)
  Inoue T, Kobirumaki-Shimozawa F, Kagemoto T, Fujii T, Terui T, Kusakari Y, Hongo K, Morimoto S, Ohtsuki I, Kurihara S, Fukuda N
- Organizer
  第90回日本生理学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22300130
[Presentation] スキンド標本を用いた拡張型心筋症マウスにおける筋長効果減弱のメカニズム2012
- Author(s)
  井上天宏、草刈洋一郎、本郷賢一、森本幸生、大槻磐男、栗原敏、福田紀男
- Organizer
  日本生理学会
- Place of Presentation
  長野県松本市
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PLANNED-23107003
[Presentation] Compensatory increase in the Ca^ transient is important for contractile recovery of dilated cardiomyopathy in mice2012
- Author(s)
  Hongo K, Morimoto S, Kusakari Y, Komukai K, Kawai M, Yoshimura M, Kurihara S
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22300130
[Presentation] Selective modulation of SERCA did not affect Ca^ leak from sarcoplasmic reticulum in transgenic mouse models2012
- Author(s)
  Morimoto S, Hongo K, Kusakari Y, Komukai K, Kawai M, Yoshimura M, Kurihara S
- Organizer
  Scientific session of American Heart Association
- Place of Presentation
  Los Angeles, CA, USA
- Data Source
  KAKENHI-PROJECT-22300130
[Presentation] Depressed length-dependent activation in skinned left ventricular muscles from a mouse model of dilated cardiomyopathy2012
- Author(s)
  Inoue T, Kusakari Y, Hongo K, Morimoto S, Ohtsuki I, Kurihara S, Fukuda N
- Organizer
  第89回日本生理学会学術集会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-22300130
[Presentation] Direct renin inhibition improved cardiac remodeling and survival in mouse model of dilated cardiomyopathy2011
- Author(s)
  Hongo K, Morimoto S, Kusakari Y, Komukai K, Kawai M, Yoshimura M, Kurihara S
- Organizer
  Scientific Session of American Heart Association
- Place of Presentation
  Orlando FL USA
- Data Source
  KAKENHI-PROJECT-22300130
[Presentation] マウス拡張型心筋症における心筋線維化に対する直接レニン阻害の効果2011
- Author(s)
  本郷賢一、森本智、草刈洋一郎、小武海公明、川井真、吉村道博、栗原敏
- Organizer
  日本生理学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22300130
[Presentation] Beta-adrenergic stimulation enhances Ca^ leak from sarcoplasmic reticulum through protein kinase A-dependent phosphorylation of ryanodine receptor under physiological condition2010
- Author(s)
  Morimoto S, O-Uchi J, Kawai M, Kusakari Y,Komukai K,Sasaki H, Yoshimura M, Hongo K,Kurihara S
- Organizer
  Scientific Session of American Heart Association
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-22300130
[Presentation] Factors modulating the effect of endothelin-1 on L-type Ca current.2010
- Author(s)
  Komukai K, O-Uchi J, Morimoto S, Kawai M, Hongo K, Yoshimura M, Kurihara S.
- Organizer
  第73回日本循環器学会学術集会
- Place of Presentation
  京都
- Year and Date
  2010-03-07
- Data Source
  KAKENHI-PROJECT-18590789
[Presentation] β-Adrenoceptor stimulation increased Ca2+ leak from sarcoplasmic reticulum without dissociation of FKBP12. 6 under physiological condition2009
- Author(s)
  Morimoto S, O-uchi J, Kawai M, Komukai K, Sasaki H, Yoshimura M, Hongo K, Kurihara S
- Organizer
  The XXXVI International Congress of Physiological Sciences
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Endothelin-1 increases L-type Ca current of rat ventricular myocytes via an activation of protein kinase C and Ca/calmodulin dependt protein kinase II.2009
- Author(s)
  Komukai K, O-Uchi J, Hongo K, Kawai M, Morimoto S, Yoshimura M, Kurihara S.
- Organizer
  American Heart Association Scientific Session 2009
- Place of Presentation
  Orlando, Florida
- Data Source
  KAKENHI-PROJECT-18590789
[Presentation] β-Adrenoceptor stimulation increased Ca leak from sarcoplasmic reticulum without dissociation of FKBP12.6 under physiological condition.2009
- Author(s)
  Morimoto S, O-uchi J, Kawai M, Komukai K, Sasaki H, Yoshimura M, Hongo K, Kurihara S
- Organizer
  The XXXVI International Congress of Physiological Sciences
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Renin-angiotensin system plays an important role in the pathogenesis of DCM in mice2009
- Author(s)
  Hongo K, et al
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-18590789
[Presentation] Angiotensin II type l receptor blockade rescued the mouse model of dilated cardiomyopathy from sudden cardiac death.2009
- Author(s)
  Hongo, et al
- Organizer
  第73回日本循環器学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-03-22
- Data Source
  KAKENHI-PROJECT-18590789
[Presentation] Endothelin-1 increases L-type Ca2+ current of rat ventricular myocytes via an activation of protein kinase C and Ca2+/calmodulin dependent protein kinaseII2009
- Author(s)
  Komukai K, O-Uchi J, Hongo K, Kawai M, Morimoto S, Yoshimura M, Kurihara S
- Organizer
  American Heart Association
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Endothelin-1 potentiates L-type Ca current by activating CaMKII in rat ventricular myocytes.2009
- Author(s)
  Komukai K, O-Uchi J, Morimoto S, Kawai M, Hongo K, Yoshimura M, Kurihara S.
- Organizer
  The 36th Congress of the International Union of Physiological Sciences.
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-18590789
[Presentation] Endothelin-1 Increases L-type Ca Current of Rat Ventricular Myocytes via an Activation of Protein Kinase C and Ca/calmodulin Dependent Protein Kinase II.2009
- Author(s)
  Komukai K, O-Uchi J, Hongo K, Kawai K, Morimoto S, Yoshimura M, Kurihara S
- Organizer
  AHA Scientific Sessions
- Place of Presentation
  Orlando USA
- Data Source
  KAKENHI-PROJECT-19590833
[Presentation] β-adrenoceptor stimulation increased Ca leak from sarcoplasmic reticulum without dissociation of FKBP12. 6 under physiological condition.2009
- Author(s)
  Morimoto S, O-Uchi J, Kawai M, Komukai K, Sasaki H, Yoshimura M, Hongo K, Kurihara S
- Organizer
  XXXVIth International Congress of Physiological Sciences
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-19590833
[Presentation] Endothelin-1 potentiates L-type Ca current by activating CaMKII in ratventricular myocytes.2009
- Author(s)
  Komukai K, O-uchi J, Morimoto S, Kawai M, Hongo K, Yoshimura M, Kurihara S
- Organizer
  The XXXVI International Congress of Physiological Sciences
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Angiotensin II type 1 receptor blockade rescued the mouse model of dilated cardiomyopathy from sudden cardiac death.2009
- Author(s)
  Hongo K
- Organizer
  第73回日本循環器学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-03-22
- Data Source
  KAKENHI-PROJECT-19590833
[Presentation] Endothelin-1 increases L-type Ca current of rat ventricular myocytesvia an activation of protein kinase C and ca/calmodulin dependent protein kinase II.2009
- Author(s)
  Fiomukai K, O-uchi J, Hongo K, Kawai M, Morimoto S, Yoshimura M, Kurihara S
- Organizer
  American Heart Association
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Renin-angiotensin system plays an important role in the pathogenesis of DCM in mouse.2009
- Author(s)
  Hongo K, Morimoto S, O-Uchi J, Kusakari Y, Komukai K, Kawai M, Yoshimura M, Morimoto S, Ohtsuki I, Takeda N, Kurihara S
- Organizer
  XXXVIth International Congress of Physiological Sciences
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-19590833
[Presentation] Endothelin-1 potentiates L-type Ca2+ current by activating CaMKII in rat ventricular myocytes2009
- Author(s)
  Komukai K, O-uchi J, Morimoto S, Kawai M, Hongo K, Yoshimura M, Kurihara S
- Organizer
  The XXXVI International Congress of Physiological Sciences
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Renin-angiotensin system plays an important role in the pathogenesis of DCM in mouse2009
- Author(s)
  Hongo K, Morimoto S, O-Uchi J, Kusakari Y, Komukai K, Kawai M, Yoshimura M, Morimoto S, Ohtsuki I, Takeda N, Kurihara S
- Organizer
  The XXXVI International Congress of Physiological Sciences
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Renin-angiotensin system plays an important role in the pathogenesis of DCM in mouse2009
- Author(s)
  Hongo K
- Organizer
  36^<th> International Congress of Physiological Sciences
- Place of Presentation
  京都
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-19590833
[Presentation] Rennin-angiotensin system plays an important role in the pathogenesis of DCM in mouse.2009
- Author(s)
  Hongo K, Morimoto S, O-uchi J, Kusakari Y, Komukai K, Kawai M, Yoshimura M, Morimoto S, Ohtsuki I, Takeda N, Kurihara S
- Organizer
  The XXXVI International Congress of Physiological Sciences
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Cardiacα1A-adrenoceptor stimulation inhibits L-type Ca2+ current in the presence ofβ-adrenoceptor stimulation through tyrosine kinase.2009
- Author(s)
  O-Uchi J, Komukai K, Morimoto S, Hongo K, Kurihara S
- Organizer
  Biophysical Society 53rd Annual Meeting
- Place of Presentation
  Boston USA
- Data Source
  KAKENHI-PROJECT-19590833
[Presentation] β-adrenoceptor stimulation accelerates Ca2+ turnover through PKA-dependent phosphorylation in saponin-treated mouse myocardium.2008
- Author(s)
  Morimoto S, O-Uchi J, Kawai M, Komukai K, Hongo K, Sasaki H, Kurihara S
- Organizer
  第84回日本生理学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590833
[Presentation] Decreased Ca2+ sensitivity of the myofilament is critcal for the development of cardiac dysfunction in mouse model of dilated cardiomyopathy2008
- Author(s)
  Hongo K, (Kurihara S)
- Organizer
  第72回日本循環器学会総会・学術集会
- Place of Presentation
  福岡
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Molecular basis for the Frank-Starling mechanism of the heart.2008
- Author(s)
  Kurihara S, Fukuda N, Ohtsuki I, Terui T, Hongo K, Komukai K, Ishikawa T
- Organizer
  心臓循環器系調節機構の病態生理学に関する国際シンポジウム
- Place of Presentation
  山形
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Decreased Ca^<2+> sensitivity of the myofilament is critical for the development of cardiac dysfunction in mouse model of dilated cardioinyopathy.2008
- Author(s)
  Hongo K
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590833
[Presentation] Endothelin-1 increases L-type Ca current via an activation of Ca/calmodulin dependent protein kinase II in rat ventricular myocytes2008
- Author(s)
  Komukai K, O-Uchi J, Morimoto S, Kawai M, Hongo K, Yoshimura M, Kurihara S
- Organizer
  日本循環器学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-18590789
[Presentation] Decreased Ca2+ sensitivity of the myofilament is critical for the development of cardiac dysfunction in mouse model of dilated cardiomyopathy2008
- Author(s)
  Hongo, et. al.
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-18590789
[Presentation] Decreased Ca^<2+>affinity of thin filament is an important factor for the development of cardiac dysfunction in mouse model of dilated cardiomyopathy.2008
- Author(s)
  0-Uchi J, Hongo K, Morimoto s. Komukai K, Kawai M, Ohtsuki I, Morimoto S*, Kurihara S(*Laboratory of clinical pharmacology, Kyushu University graduate school of medicine)
- Organizer
  Thick and thin filament regulation in striated muscle
- Place of Presentation
  Madison, USA
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Decreased Ca^<2+> sensitivity of the myofilament is critcal for the d-evelopment of cardiac dysfunction in mouse model of dilated car-diomyopathy2008
- Author(s)
  Hongo K
- Organizer
  第72回日本循環器学会総会・学術集会
- Place of Presentation
  福岡
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Endothelin-1 increases L-type Ca current via an activation of Ca/calmodulin- dependent protein kinase II in rat ventricular myocytes2008
- Author(s)
  Komukai K, O-Uchi J, Morimoto S, Kawai M, Hongo K, Yoshimura M, Kurihara S.
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18590789
[Presentation] Molecular basis for the Frank-Starli-ng mechanism of the heart2008
- Author(s)
  Kurihara S, Fukuda N, Ohtsuki I, Terui T, Hongo K, Komukai K, Ishikawa T
- Organizer
  心臓循環器系調節機構の病態生理学に関する国際シンポジウム
- Place of Presentation
  山形
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Decreased Ca2+ affinity of thin filament is an important factor for the development of cardiac dysfunction in mouse model of dilated cardiomyopathy2008
- Author(s)
  O-Uchi J, Hongo K, Morimoto S, Komukai K, Kawai M, Ohtsuki I, Morimoto S, Kurihara S
- Organizer
  Thick and thin filament regulation in striated muscle
- Place of Presentation
  Madison, USA
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Endothelin-1 increases L-type Ca current via an activation of Ca/calmodulin-dependent protein kinase II in rat ventricular myocytes.2008
- Author(s)
  Komukai K, O-Uchi J, Morimoto S, Kawai M, Hongo K, Yoshimura M, Kurihara S
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590833
[Presentation] Decreased Ca2+ sensitivity of the myofilament is critical for the development of cardiac dysfunction in mouse model of dilated cardiomyopathy.2008
- Author(s)
  Hongo K, Morimoto S, Komukai K, Kawai M, O-Uchi J, Yoshimura M, Kurihara S
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590833
[Presentation] Changes in Ca2+ transient and contraction of left ventricular papillary muscles in mouse model of dilated cardiomyopathy2007
- Author(s)
  Hongo K, (Kurihara S)
- Organizer
  The 24th annual meeting of the International Society for Heart Research Japanese Section
- Place of Presentation
  Ferrara, Italy
- Year and Date
  2007-06-21
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Altered Ca^<2+> handling could contribute to the cardiac sudden dea-th in knock-in mouse of dilated cardiomyopathy2007
- Author(s)
  Hongo K
- Organizer
  第30回心筋代謝研究会
- Place of Presentation
  京都
- Year and Date
  2007-07-15
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Effect of endothelin-1 on L-type Ca current in rat ventricular myocytes.2007
- Author(s)
  Komukai K, O-Uchi J, Morimoto S, Kawai M, Hongo K, Kurihara S.
- Organizer
  第11回日本心不全学会学術集会
- Place of Presentation
  浦安
- Data Source
  KAKENHI-PROJECT-18590789
[Presentation] Altered Ca2+ handling could contribute to the cardiac sudden death in knock-in mouse of dilated cardiomyopathy2007
- Author(s)
  Hongo K, (Kurihara S)
- Organizer
  第30回心筋代謝研究会
- Place of Presentation
  京都
- Year and Date
  2007-07-15
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Changes in Ca2+ transient and contraction of left ventricular papillary muscles in mouse model of dilated cardiomyopathy2007
- Author(s)
  Hongo, et. al.
- Organizer
  The 24th Annual Meeting of ISHR Japanese Section
- Place of Presentation
  Ferrara,Italy
- Year and Date
  2007-06-21
- Data Source
  KAKENHI-PROJECT-18590789
[Presentation] Changes in Ca^<2+> transient and contraction of left ventricular pap-illary muscles in mouse model of dilated cardiomyopathy2007
- Author(s)
  Hongo K
- Organizer
  The 24th annual meeting of the International Society for Heart Research Japanese Section
- Place of Presentation
  Ferrara,Italy
- Year and Date
  2007-06-21
- Data Source
  KAKENHI-PROJECT-19500357
[Presentation] Altered Ca2+ handling could contribute to the cardiac sudden deathin Knock-in mouse of dilated cardiomyopathy2007
- Author(s)
  Hongo, et. al.
- Organizer
  第30回心筋代謝研究会
- Place of Presentation
  京都
- Year and Date
  2007-07-15
- Data Source
  KAKENHI-PROJECT-18590789
[Presentation] Direct Renin Inhibition Improved Cardiac Remodeling and Survival in Mouse Model of Dilated Cardiomyopathy.
- Author(s)
  Hongo K
- Organizer
  American Heart Association 2011 Scientific sessions
- Place of Presentation
  Orland, FL, USA
- Data Source
  KAKENHI-PROJECT-22300130
[Presentation] Compensatory Increase in the Ca2+ Transient Is Important for Contractile Recovery of Dilated Cardiomyopathy in Mice.
- Author(s)
  Hongo K
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22300130

1. KUSAKARI Yoichiro (80338889)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
2. KOMUKAI Kimiaki (60360145)

# of Collaborated Projects: 5 results

# of Collaborated Products: 50 results
3. KURIHARA Satoshi (90057026)

# of Collaborated Projects: 5 results

# of Collaborated Products: 30 results
4. KAWAI Makoto (40277025)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
5. OTSU Kinya (20294051)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. FUKUDA Norio (30301534)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. MORIMOTO Sachio (50202362)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
8. SASAKI Hiroyuki (60170693)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
9. TERUI TAKAKO (10366247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. KOBIRUMAKI FUYU (40548905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. OYAMA KOTARO (70632131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. URASHIMA Takashi (20338875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KONISHI Masato (20138746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 橋本和弘 (30172860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 角田亘 (00453788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 田中悦子 (70256410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HONGO Kenichi 本郷 賢一

本郷 賢一 ホンゴウ ケンイチ

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Role of selective modulation of sarcoplasmic reticulum function on cardiac contraction during ischemia.Principal Investigator

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Mechanism of diastolic dysfunction in pressure-overloaded mouse heartPrincipal Investigator

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虚血時心筋収縮力低下に対する長さ依存性代償機転の関与とその調節機序Principal Investigator

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カーボンファイバー法によるラット単離心室筋細胞の伸長・短縮Principal Investigator

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[Journal Article] Alpha_1-adrenenoceptor stimulation inhibits cardiac excitation-contraction coupling through tyrosine phosphorylation of beta_1-adrenoceptor2013

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[Journal Article] Depressed Frank-Starling mechanism in the left ventricular muscle of the knock-in mouse model of dilated cardiomyopathy with troponin T deletion mutation ΔK2102013

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[Journal Article] カルシウム拮抗薬の心保護作用2010

HONGO Kenichi 本郷賢一

本郷賢一ホンゴウケンイチ