SUGAHARA Takuya 菅原卓也

… Alternative Names

Sugahara Takuya 菅原卓也

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Researcher Number	00263963
Other IDs	https://orcid.org/0000-0002-0335-8273
Affiliation (Current)	2025: 愛媛大学, 農学研究科, 教授
Affiliation (based on the past Project Information) *help	2025: 愛媛大学, 農学研究科, 教授 2019 – 2023: 愛媛大学, 農学研究科, 教授 2017: 愛媛大学, 大学院農学研究科, 教授 2016 – 2017: 愛媛大学, 農学研究科, 教授 2012 – 2015: 愛媛大学, 農学部, 教授 … More 2009 – 2011: Ehime University, 農学部, 准教授 2006: 愛媛大学, 農学部, 准教授 2006: Ehime University, Faculty of Agriculture, Associate Professor, 農学部, 助教授 2005: 愛媛大学, 農学部, 講師 2004 – 2005: 愛媛大学, 農学部, 助手 1998 – 2001: 愛媛大学, 農学部, 助手 Less
Review Section/Research Field	Principal Investigator Food science / Basic Section 38050:Food sciences-related / 食品科学・栄養科学 Except Principal Investigator Basic Section 38050:Food sciences-related / 反応・分離工学 / Epidemiology and preventive medicine / Biofunction/Bioprocess / Hygiene and public health
Keywords	Principal Investigator 抗炎症効果 / リゾチーム / 脱顆粒抑制効果 / 抗アレルギー効果 / 抗炎症 / サイトカイン産生 / マクロファージ / 構造活性相関 / 抗アレルギー / 機能性食品 … More / 抗体産生促進因子 / 無血清培養 / ハイブリドーマ / モノクローナル抗体 / 好塩基球 / 脱顆粒 / ペプチド / アスパラギン酸含有ペプチド / ジペプチド / グルタミン酸含有ペプチド / IgE産生抑制効果 / Gnetin C / アレルギー性鼻炎 / レスベラトロール / ピセアタンノール / Scripsin B / 脱顆粒抑制 / IgE産生抑制 / Gunetin C / Scripusin B / Piceatannol / Resveratrol / グネチンC / スキルプシンB / パッションフルーツ / 腫瘍壊死因子α / 一酸化窒素 / 腹腔マクロファージ / 全身性炎症症候群 / 腫瘍壊死因子(TNF)-α / インターロイキン(IL)-6 / 遺伝子発現抑制 / 全身性炎症モデルマウス / 貪食活性 / 炎症性サイトカイン / インターロイキン6 / TNF-α / anti-cancer activity / allergy suppression / proteose-peptone / milk / cytokine production / antibody production / immunostimulation / fermented milk / 抗ガン活性 / アレルギー抑制 / プロテオースペプトン / 牛乳 / 抗体産生 / 免疫調節 / 発酵乳 / ブリ類結節症 / ヒラメ滑走細菌 / JNK / TLR4 / 樹状細胞 / 自然免疫 / コラーゲン / 免疫促進効果 / アマニリグナン / 脂肪肝抑制 / 抗糖尿病効果 / 脂肪蓄積抑制効果 / 脂肪蓄積抑制 / 免疫促進 / リグナン / マタイレジノール / セコイソラリシレジノール / アマニ / ハイプリドーマ / 産生促進 / ヒト末梢血リンパ球 … More Except Principal Investigator DDS / 遺伝子導入 / 海藻レクチン / 脂質ベシクル / リポソーム / 癌細胞 / 癌治療 / Alga lectin / Immunovesicle / Liposome / Gene transfection / プロテインA / IgM / Span80 / Hybridoma / Lipid vesicle / Cancer Therapy / 抗アレルギー活性 / 代謝 / 有機合成化学 / 抗アレルギー作用 / secoisolariciresinol / lariciresinol / 立体特異性 / 立体異性体 / 代謝化合物 / 脂肪細胞分化抑制効果 / 抗炎症作用 / 脱顆粒抑制活性 / conidendrin / 体内代謝物 / リグナン / organic synthesis / metabolite / lignan / I型アレルギー / 果皮（果皮） / 葉（柑橘） / 果皮・葉抽出物 / 抗アレルギー / マーマレード / 果皮 / 葉 / 相加・相乗効果 / RBL-2H3細胞 / ペアリング / Aktのリン酸化 / 脱顆粒抑制 / シークヮーサー果皮 / シークヮーサー葉 / 水蒸気蒸留法 / gamma-テルピネン / リモネン / 唾液アミラーゼ活性 / 香気成分 / シークヮーサー精油 / リン酸化制御 / 脱顆粒シグナリング / ラクトフェリン / ノビレチン / 葉・果皮抽出物 / シークヮーサー / 抗ストレス効果 / 抗アレルギー効果 / 頸動脈肥厚 / 動脈硬化 / 血圧 / 就寝時血圧 / 起床時血圧 / 健診時血圧 / 睡眠呼吸障害 / 睡眠の質 / 頚動脈壁肥厚 / Apoptosis / Cancer therapy / アポトーシス / ヒト脳腫瘍 / ヒト大腸癌 / 中性界面活性剤 / レクチン / ベシクル / ニオソーム / ハイブリドーマ / 糖鎖 / イムノベシクル / PAA / インターロイキン８ / 炎症 / 好酸球増多筋痛症 / 食品衛生 / 好酸球増多筋痛症(EMS) / サプリメント / IL-8 / EoL-3 / ケモカイン / ケモカインレセプター / 走化性 / 好中球 / 不純物 / 好酸球 / トリプトファン Less

酸性アミノ酸含有ジペプチドの保健機能と作用機構の解明Principal Investigator
- Principal Investigator
  
  菅原卓也
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Ehime University
Evaluation of health function and the mode of action of dipeptides containing glutamic acid.Principal Investigator
- Principal Investigator
  
  菅原卓也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Ehime University
Biological activity of lignan metabolite contains in dietary plant
- Principal Investigator
  
  Yamauchi Satoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Ehime University
Elucidation of type I allergy regulation mechanism by Shekwasher leaf and peel and examination of the effective utilization method
- Principal Investigator
  
  Okamoto Takeaki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Ehime University
Evaluation of health functions of scirpusin B from passion fruit seedsPrincipal Investigator
- Principal Investigator
  
  Sugahara Takuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Ehime University
Anti-inflammatory effect of hen egg white lysozymePrincipal Investigator
- Principal Investigator
  
  Sugahara Takuya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Ehime University
The elucidation of the mechanisms behind the allergic reaction induced by tryptophan supplement byproducts.
- Principal Investigator
  
  OKAMOTO Takeaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Ehime University
Impact of Sleep Disordered Breathing and Home and Office Blood Pressure on Carotid Arterial Wall Thickness: the Toon Health Study
- Principal Investigator
  
  Eguchi Eri
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  Okayama University
  Ehime University
Effect of collagen on the innate immune system.Principal Investigator
- Principal Investigator
  
  SUGAHARA Takuya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Ehime University
Studies on the structure-activity relationship of flaxseed lignan, multifunctional physiologically active substancePrincipal Investigator
- Principal Investigator
  
  SUGAHARA Takuya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Ehime University
Preparation and the function of a novel surfactant vesicle with a recognition ability of the specific antigen of cancer cell toward practical clinical application
- Principal Investigator
  
  KATO Keiichi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Ehime University
Studies on a novel immunostimulation factor in fermented milk.Principal Investigator
- Principal Investigator
  
  SUGAHARA Takuya
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Ehime University
熱変性リゾチームの抗体産生促進活性増強メカニズム解明に関する研究Principal Investigator
- Principal Investigator
  
  菅原卓也
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  Ehime University
癌細胞への標的指向能を付与した表面修飾脂質ベシクルの創製とその機能
- Principal Investigator
  
  加藤敬一
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Ehime University
Practical development of the lipid vesicle as surfactant assemblies having a functional molecular-recognition -toward to a cancer therapy in DDS-
- Principal Investigator
  
  KATO Keichi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for University and Society Collaboration
- Research Field
  
  反応・分離工学
- Research Institution
  Ehime University
癌細胞への標的指向能を付与した表面修飾脂質ベシクルの創製とその機能
- Principal Investigator
  
  KATO Keiichi
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Ehime University
ニワトリ卵白由来リゾチームの抗体産生促進活性に関する研究Principal Investigator
- Principal Investigator
  
  菅原卓也
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  Ehime University
Preparation of the vesicle as surfactant assemblies having a functional molecular -recognition -toward to a cancer therapy in DDS-
- Principal Investigator
  
  KATO Keiichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  反応・分離工学
- Research Institution
  Ehime University

[Book] The effect of secoisolariciresinol on 3T3-L1 adipocytes and the relationship between molecular structure and the activity.2010
- Author(s)
  S. Tominaga, T. Sugahara, S. Nishimoto, M. Yamawaki, Y. Nakashima, T. Kishida, K. Akiyama, M. Maruyama and S. Yamauchi
- Publisher
  Animal Cell Technology : Basic & Applied Aspects
- Data Source
  KAKENHI-PROJECT-21580142
[Journal Article] p-Synephrine suppresses inflammatory responses in lipopolysaccharide-stimulated RAW264.7 cells and alleviates systemic inflammatory response syndrome in mice.2022
- Author(s)
  M. Ishida, C. Takekuni, K. Nishi, T. Sugahara
- Journal Title
  
  Food and Function
  
  Volume: In press Issue: 9 Pages: 1-11
- DOI
  10.1039/d2fo00299j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05895, KAKENHI-PROJECT-19K15790, KAKENHI-PROJECT-20K05891
[Journal Article] Anti-allergy potential of Averrhoa bilimbi Linn. fruit water extract shown by its suppressive effect on the degranulation of RBL-2H3 cells.2021
- Author(s)
  Santoso W.H , Ishida M , Nishi K , Sugahara T , Putra A.B.N
- Journal Title
  
  Journal of Functional Food and Nutraceutical
  
  Volume: In Press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05895
[Journal Article] Discovery of stereospecific cytotoxicity of (8R,8'R)-trans-arctigenin against insect cells and structure-activity relationship on aromatic ring.2020
- Author(s)
  S. Yamauchi, A. Nishimoto, H. Nishiwaki, K. Nishi, T. Sugahara
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 30 Issue: 13 Pages: 127191-127191
- DOI
  10.1016/j.bmcl.2020.127191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05895, KAKENHI-PROJECT-20K05891
[Journal Article] Anti-inflammatory effect of lysozyme from hen egg white on mouse peritoneal macrophages2018
- Author(s)
  Tagashira Ayuka、Nishi Kosuke、Matsumoto Shinya、Sugahara Takuya
- Journal Title
  
  Cytotechnology
  
  Volume: 印刷中 Issue: 3 Pages: 929-938
- DOI
  10.1007/s10616-017-0184-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07792, KAKENHI-PROJECT-15K07432
[Journal Article] Immunostimulatory effect of spinach aqueous extract on mouse macrophage-like J774.1 cells and mouse primary peritoneal macrophages.2016
- Author(s)
  M. Ishida, S. Ose, K. Nishi and T. Sugahara
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 80 Issue: 7 Pages: 1393-1402
- DOI
  10.1080/09168451.2016.1146068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07432
[Journal Article] Jellyfish collagen stimulates maturation of mouse bone marrow-derived dendritic cells.2015
- Author(s)
  Putra A.B.N., Nishi K., Shiraishi R., Doi M. and Sugahara T.
- Journal Title
  
  Journal of Functional Foods
  
  Volume: 14 Pages: 308-317
- DOI
  10.1016/j.jff.2015.02.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580188
[Journal Article] Jellyfish collagen stimulates production of TNF-α and IL-6 by J774.1 cells through activation of NF-kappaB and JNK via TLR4 signaling pathway.2014
- Author(s)
  Putra A.B.N., Nishi K., Shiraishi R. Moi M. and Sugahara T.
- Journal Title
  
  Molecular Immunology
  
  Volume: 58 Issue: 1 Pages: 32-37
- DOI
  10.1016/j.molimm.2013.11.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580188
[Journal Article] Immunomodulatory activity of Bengkoang (Pachyrhizus erosus) fiber extract in vitro and in vivo2013
- Author(s)
  Ika Dyah Kumalasari et al.
- Journal Title
  
  Cytotechnology
  
  Volume: in press Issue: 1 Pages: 75-85
- DOI
  10.1007/s10616-013-9539-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710042, KAKENHI-PROJECT-24580188
[Journal Article] Activation of J774.1 murine macrophages by lactate dehydrogenase2013
- Author(s)
  Miho Daifuku, Kosuke Nishi, Takeaki Okamoto, Takuya Sugahara
- Journal Title
  
  Cytotechnology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460804
[Journal Article] (-)-Secoisolariciresinol attenuates high-fat diet-induced obesity in C57BL/6 mice.2012
- Author(s)
  S. Tominaga, K. Nishi, S. Nishimoto, Y. Nakashima, K. Akiyama, S. Yamauchi and T. Sugahara
- Journal Title
  
  Food Funct.
  
  Volume: 3 Pages: 76-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580142
[Journal Article] Immunomodulatory effect of(-)-matairesinol in vivo and ex vivo.2011
- Author(s)
  M. Yamawaki, K. Nishi, S. Nishimoto, S. Yamauchi, K. Akiyama, T. Kishida, M. Maruyama, H. Nishiwaki and T. Sugahara
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 75 Pages: 859-863
- NAID
  10028272385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580142
[Journal Article] Antifungal activity of morinol B derivatives of tetrahydropyran sesquilignan.2010
- Author(s)
  K. Masuda, H. Nishiwaki, K. Akiyama, S. Yamauchi, M. Maruyama, T. Sugahara and T. Kishida
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 74 Pages: 2071-2076
- NAID
  10027560608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580142
[Journal Article] IgE suppressive activity of(-)-matairesinol and structure-activity relationship.2010
- Author(s)
  S. Kawahara, I. Iwata, E. Fujita, M. Yamawaki, H. Nishiwaki, T. Sugahara, S. Yamauchi, K. Akiyama and T. Kishida
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 74 Pages: 1878-1883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580142
[Journal Article] The Effect of secoisolariciresinol on 3T3-L1 adipocytes and the relationship between molecular structure and the activity2010
- Author(s)
  S.Tominaga, T.Sugahara, et al.
- Journal Title
  
  Animal Cell Technology : Basic & Applied Aspects 16(In press)
- Data Source
  KAKENHI-PROJECT-21580142
[Journal Article] Improved syntheses of morinol C and D by employing Mizoroki-Heck 4 reaction and their cytotoxic and antimicrobial activities.2010
- Author(s)
  K. Ogura, T. Sugahara, M. Maruyama, K. Akiyama and S. Yamauchi
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 74 Pages: 1641-1644
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580142
[Journal Article] Antimicrobial activity of stereoisomers of butane type of lignans.2009
- Author(s)
  Y. Kawaguchi, S. Yamauchi, K. Masuda, H. Nishiwaki, K. Akiyama, M. Maruyama, T. Sugahara, T. Kishida and Y. Koba
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 73 Pages: 1806-1810
- NAID
  10027544582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580142
[Journal Article] Syntheses and antimicrobial activity of tetrasubstituted tetrahydrofuran lignan stereoisomers.2009
- Author(s)
  T. Nakato, S. Yamauchi, R. Tago, K. Akiyama, M. Maruyama, T. Sugahara, T. Kishida and Y. Koba
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 73 Pages: 1608-1617
- NAID
  10027543720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580142
[Journal Article] Immunostimulation Effect of the Fermented Milk on Human Hybridomas and Peripheral Blood Lymphocytes2006
- Author(s)
  T.Sugahara, K.Nakamoto, K.Hara
- Journal Title
  
  Animal Cell Technology : Basic & Applied Aspects (In press)
- Data Source
  KAKENHI-PROJECT-16580102
[Journal Article] Preparation and characterization of non-ionic vesicles cantaining Span 80 or Span 852006
- Author(s)
  Kato, K., Walde, P, Koine, N., Imai, Y., Akiyama, K, Sugahara, T
- Journal Title
  
  Journal of Dispersion Science and Technology 27,8(印刷中)
- Data Source
  KAKENHI-PROJECT-16360415
[Journal Article] Immunostimulation Effect of the Fermented Milk on Human Hybridomas and Peripheral Blood Lymphocytes.2006
- Author(s)
  T.Sugahara, K.Nakamoto, K.Hara
- Journal Title
  
  Animal Cell Technology : Basic ＆ Applied Aspects 14
  
  Pages: 185-191
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580102
[Journal Article] Preparation of cationic immunovesicles containing cationic peptide lipid for specific drug delivery to target cells2005
- Author(s)
  T.Sugahara, S.Kawashima, A.Oda, Y.Hisaeda, K.Kato
- Journal Title
  
  Cytotechnology 47
  
  Pages: 51-57
- Data Source
  KAKENHI-PROJECT-16360415
[Journal Article] Gene transfection into Hela cells by vesicles containing cationic peptide lipid2005
- Author(s)
  Y.Ohama, Y.Heike, T.Sugahara, K.Sakata, N.Yoshimura, Y.Hisaeda, M.Hosokawa, S.Takashima, K.Kato
- Journal Title
  
  Bioscience, Biotechnology and Biochemistry 69,8
  
  Pages: 1453-1458
- NAID
  130000030229
- Data Source
  KAKENHI-PROJECT-16360415
[Journal Article] Immunostimulation effects of proteose-peptone component 3 fragment on human hybridomas and peripheral blood lymphocytes.2005
- Author(s)
  T.Sugahara, H.Onda, Y.Shinohara, M.Hori, K.Akiyama, K.Nakamoto, K.Hara
- Journal Title
  
  Biochim.Biophys.Acta 1725
  
  Pages: 233-240
- Data Source
  KAKENHI-PROJECT-16580102
[Journal Article] Preparation of cationic immunovesicles containing cationic peptide lipid for specific drug delivery to target cells2005
- Author(s)
  Takuya Sugahara
- Journal Title
  
  Cytotechnology 47
  
  Pages: 51-57
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16360415
[Journal Article] Immunostimulation effects of proteose-peptone component 3 fragment on human hybridomas and peripheral blood lymphocytes.2005
- Author(s)
  T.Sugahara, H.Onda, Y.Shinohara, M.Horii, K.Akiyama, K.Nakamoto, K.Hara
- Journal Title
  
  Biochimca Biophysica Acta 1725
  
  Pages: 233-240
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580102
[Journal Article] ドラッグデリバリーシステムによる癌治療および遺伝子導入2004
- Author(s)
  加藤敬一, 菅原卓也, 秋山浩一ら
- Journal Title
  
  日本エム・イー学会誌生体医工学第42巻特別号II
  
  Pages: 185-185
- Data Source
  KAKENHI-PROJECT-16360415
[Journal Article] Specific targeting at ERM5-1 cell as a model human-brain tumor cell and the anti-tumor effect by using immunovesicle2004
- Author(s)
  Keiichi Kato, Taichi Manabe, Takuya Sugahara et al.
- Journal Title
  
  Proc.of the 10^<th> Asian Pacific Confederatio of Chem.Eng.(APCChE)
- NAID
  130005052554
- Data Source
  KAKENHI-PROJECT-16360415
[Journal Article] Immunostimulation Effect of the Fermented Milk on Human Hybridomas and Peripheral Blood Lymphocytes
- Author(s)
  Takuya Sugahara
- Journal Title
  
  Animal Cell Technology : Basic & Applied Aspects 発表予定
- Data Source
  KAKENHI-PROJECT-16580102
[Patent] 発酵乳中の免疫増強組成物2004
- Inventor(s)
  菅原卓也, 原和志, 中本勝教
- Industrial Property Rights Holder
  愛媛大学, 四国乳業
- Patent Publication Number
  2006-076961
- Filing Date
  2004
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580102
[Presentation] Anti-allergic effect of glutamyl dipeptides2024
- Author(s)
  Takuya Sugahara, Taiki Hirakawa, Mitsumasa Izumi, Senri Yurue, Momoko Ishida, Kosuke Nishi
- Organizer
  the 22nd World Congress of Food Science and Technology IUFoST2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05512
[Presentation] Small compounds and their biological roles.2023
- Author(s)
  Takuya Sugahara
- Organizer
  Agricultural Product Technology Study Program, University of Jember
- Invited
- Data Source
  KAKENHI-PROJECT-22K05512
[Presentation] Functional foods in Japan: Regulation and effects on health.2023
- Author(s)
  Takuya Sugahara
- Organizer
  Faculty of Agricultural Technology, Gadjah Mada University, Indonesia
- Invited
- Data Source
  KAKENHI-PROJECT-22K05512
[Presentation] Anti-allergic effect of peptides.2023
- Author(s)
  Sugahara T., Hirakawa T., Izumi M., Yurue S., Ishida M. and Nishi K.
- Organizer
  The 2nd International Conference on Food Technology and Nutrition (IC-FTN 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05512
[Presentation] 煮干酵素処理液の抗アレルギー効果に関する研究2023
- Author(s)
  淘江千緑、平川泰己、和泉光将、石田萌子、西　甲介、菅原卓也
- Organizer
  日本農芸化学会2023年度中四国・西日本支部合同大会
- Data Source
  KAKENHI-PROJECT-22K05512
[Presentation] Piceatannol及びその類縁化合物の抗アレルギー効果に関する研究2021
- Author(s)
  村上裕紀, 石田萌子, 西甲介, 菅原卓也
- Organizer
  日本動物細胞工学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19K05895
[Presentation] (-)-β-conidendrin及びその立体異性体の脱顆粒抑制効果に関する研究2021
- Author(s)
  石田萌子、松原依莉彩、西甲介、山内聡、菅原卓也
- Organizer
  第３４回動物細胞工学会JAACT2021
- Data Source
  KAKENHI-PROJECT-21K05439
[Presentation] レスベラトロールおよびその類縁化合物の抗アレルギー効果2021
- Author(s)
  村上裕紀・水崎　愛・西　甲介・石田萌子・菅原卓也
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19K05895
[Presentation] パッションフルーツ種子成分の抗アレルギー効果に関する研究2019
- Author(s)
  水崎　愛、石田萌子、西　甲介、菅原卓也
- Organizer
  日本動物細胞工学会2019年度大会
- Data Source
  KAKENHI-PROJECT-19K05895
[Presentation] Passion fruit seed extract suppressed IgE production.2019
- Author(s)
  Sugahara T, Mizusaki A., Ishida M. and Nishi K.
- Organizer
  The 16th ASEAN Food Conference 2019 (AFC2019)
- Data Source
  KAKENHI-PROJECT-19K05895
[Presentation] 卵白由来リゾチームのマクロファージに対する抗炎症効果2018
- Author(s)
  田頭歩佳・西　甲介・松本真弥・菅原卓也
- Organizer
  日本動物細胞工学会2017年度大会
- Data Source
  KAKENHI-PROJECT-15K07432
[Presentation] Anti-inflammatory effect of lysozyme from hen egg white on macrophages.2017
- Author(s)
  Tagashira A., Nishi K., Mastumoto S. and Sugahara T.
- Organizer
  The 10th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07432
[Presentation] Effects of 3-phenylamino-L-alanine (PAA) and 4-aminophenol (4-AP) on chemotaxis and expression of chemokine receptors in human eosinophils2016
- Author(s)
  Ayuka Tagashira, Takeaki Okamoto, Akira Yamauchi, Kosuke Nakano, Kosuke Nishi, Takuya Sugahara
- Organizer
  The 17th International Biotechnology Symposium and Exhibition (IBS 2016)
- Place of Presentation
  Melbourne Convention Centre, Melbourne（Australia）
- Year and Date
  2016-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460804
[Presentation] Effect of lysozyme on RAW264.7 cells stimulated by lipopolysaccharide2016
- Author(s)
  Takuya Sugahara, Shinya Matsumoto, and Kosuke Nishi
- Organizer
  International Biotechnology Symposium 2016
- Place of Presentation
  オーストラリア　メルボルン
- Year and Date
  2016-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07432
[Presentation] Effect of lysozyme on RAW264.7 cells stimulated by lipopolysaccharide.2016
- Author(s)
  Sugahara T., Matsumoto S. and Nishi K.
- Organizer
  The 17th International Biotechnology Symposium and Exhibition (IBS2016)
- Place of Presentation
  メルボルンコンベンションセンター　（メルボルン、オーストラリア)
- Year and Date
  2016-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07432
[Presentation] Jellyfish collagen stimulates production of TNF-α and IL-6 by J774.1 cells through TLR4 signaling pathway.2014
- Author(s)
  Agus Budiawan Naro Putra, Kosuke Nishi, Ryusuke Shiraishi, Mihikaru Doi, Takuya Sugahara
- Organizer
  International Conference and Exhibition on Nutraceuticals and Functional Foods (ISNFF2014)
- Place of Presentation
  Istanbul, Turkey
- Data Source
  KAKENHI-PROJECT-24580188
[Presentation] ヒト末梢血由来好酸球の走化性に及ぼすPAAおよび4-APの影響2013
- Author(s)
  岡本威明、田頭歩佳、山内明、菅原卓也
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25460804
[Presentation] Studies on the immunostimulatory effects of jellyfish collagen on macrophage.2012
- Author(s)
  Putra A.B.N., Morishige H., Nishimoto S., Nishi K., Shiraishi R., Doi M. and Sugahara T.
- Organizer
  The 25th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2012)
- Place of Presentation
  Nagoya, Japan
- Data Source
  KAKENHI-PROJECT-24580188
[Presentation] Anti-cancer effect of lectin from red sea alga.2011
- Author(s)
  T. Sugahara
- Organizer
  The 2nd International Symposium on Temulawak
- Place of Presentation
  Bogor Indonesia
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] ブタノール型セコシクロリグナンの合成と培養細胞に対する活性2011
- Author(s)
  富山千聖, 西脇寿, 西甲介, 菅原卓也, 山内聡
- Organizer
  2011年度日本農芸化学会西日本支部・中四国支部合同大会(要旨集)
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] 細胞毒性報告のあるセコシクロリグナンの全立体異性体の合成と細胞に対する活性2011
- Author(s)
  富山千聖, 西脇寿, 山脇愛実, 菅原卓也, 山内聡
- Organizer
  日本農芸化学会2011年度大会(要旨集)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] Anti-cancer effect of lectin from red sea alga2011
- Author(s)
  T.Sugahara
- Organizer
  The 2nd International Symposium on Temulawak
- Place of Presentation
  ボゴニル(インドネシア)(招待講演)
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] Effect of flaxseed lignan on lipid accumulation in adipocytes.2011
- Author(s)
  T. Sugahara, S. Tominaga, S. Yamauchi, S. Nishimoto and K. Nishi
- Organizer
  International Conference on Food Factors(ICoFF) 2011
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] Effect of flaxseed lignan on lipid accumulation in adipocytes2011
- Author(s)
  T.Sugahara, et al
- Organizer
  International Conference on Food Factors (ICOFF) 2011
- Place of Presentation
  台北(台湾)
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] Effect of secoisolariciresinol on adipogenesis.2010
- Author(s)
  T. Sugahara, S. Tominaga, S. Yamauchi, M. Maruyama, K. Akiyama and S. Nishimoto
- Organizer
  The 14th International Biotechnology Symposium and Exhibition(IBS2010)
- Place of Presentation
  Rimini, Italy
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] Effect of secoisolariciresinol on adipogenesis.2010
- Author(s)
  Sugahara, et al.
- Organizer
  14th International Biotechnology Symposium and Exhibition
- Place of Presentation
  イタリア、リミニ市
- Year and Date
  2010-09-15
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] Evaluation of food functions by animal cell culture and experimental animals.2010
- Author(s)
  Sugahara, et al.
- Organizer
  Gadjah Mada-Ehime Network Symposium 2010
- Place of Presentation
  インドネシア、バリ
- Year and Date
  2010-08-07
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] Secoisolariciresinolの高脂肪食餌性肥満に与える影響2010
- Author(s)
  冨永詩央里, 西本壮吾, 山内聡, 丸山雅史, 秋山浩一, 菅原卓也
- Organizer
  日本農芸化学会2010年度大会(要旨集)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] (-)マタイレジノールの構造と細胞毒性活性、IgE抗体産生抑制活性との関係2010
- Author(s)
  河原沙耶, 岩田一平, 山内聡, 菅原卓也, 藤田絵里子, 山脇愛美, 岸田太郎, 秋山浩一
- Organizer
  日本農芸化学会2010年度大会(要旨集)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] Evaluation of food functions by animal cell culture and experimental animals.2010
- Author(s)
  T. Sugahara, K. Nishi and S. Nishimoto
- Organizer
  Gadjah Mada-Ehime Network(GEN) 2010
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2010-08-07
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] (-)-morinol Bの7位のベンゼン環上の置換基が抗かび活性に与える影響2010
- Author(s)
  升田健太, 山内聡, 西脇寿, 秋山浩一, 菅原卓也
- Organizer
  日本農芸化学会2010年度大会(要旨集)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] Studies on the immunoregulatory functions of orange.2009
- Author(s)
  T. Sugahara
- Organizer
  Seminar National 2009 Developing local-resource-based technology
- Place of Presentation
  Yogyakarta, Indonesia
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] Animal cell technology-Studies on function of food2009
- Author(s)
  Takuya Sugahara
- Organizer
  Seminar National 2009 Developing local-resource-based technology
- Place of Presentation
  Yogyakarta, Indonesia
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] (-)-Matairesinolの免疫調節活性に関する研究2009
- Author(s)
  山脇愛実, 菅原卓也, 山内聡, 西本壮吾, 岸田太郎, 秋山浩一, 丸山雅史, 西脇寿
- Organizer
  日本農芸化学会関西・中四国・西日本支部、日本栄養・食糧学会九州・沖縄支部、および日本食品科学工学会西日本支部2009年度合同沖縄大会(要旨集)
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-21580142
[Presentation] Effect of contaminant PAA on chemotaxis and expression of IL-8 receptor in human eosinophils
- Author(s)
  Takeaki Okamoto, Ayuka Tagashira, Momoru Tanaka, Takuya Sugahara
- Organizer
  The International Society for Nutraceuticals and Functional Foods (ISNFF2014)
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2014-10-14 – 2014-10-17
- Data Source
  KAKENHI-PROJECT-25460804
[Presentation] Collagen from jellyfish stimulates mouse bone marrow-derived dendritic cells.
- Author(s)
  Putra A.B.N., Nishi K., Shiraishi R., Doi M. and Sugahara T.
- Organizer
  12th Asian Congress of Nutrition (ACN2015 )
- Place of Presentation
  横浜(日本)
- Year and Date
  2015-05-14 – 2015-05-17
- Data Source
  KAKENHI-PROJECT-24580188
[Presentation] Immunostimulatory effects of jellyfish collagen on mouse bone marrow-derived dendritic cells.
- Author(s)
  Putra A.B.N., Nishi K., Shiraishi R., Doi M. and Sugahara T.
- Organizer
  7th International Conference and Exhibition on Nutraceuticals and Functional Foods (ISNFF 2014)
- Place of Presentation
  イスタンブール(トルコ）
- Year and Date
  2014-10-14 – 2014-10-17
- Data Source
  KAKENHI-PROJECT-24580188

1. KATO Keiichi (10117088)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
2. TATEISHI Norihiko (90236555)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. SATO Motomichi (50162491)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SUZUKI Yoji (20226567)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. YAMAUCHI Satoshi (00243808)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
6. OKAMOTO Takeaki (20398431)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. KATO Tadahiro (60325363)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. SAEKI Toshiaki

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. YAMAUCHI Akira (80372431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. AKIYAMA Koichi (80231835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. MASUDA Seizo (50363263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Eguchi Eri (60635118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TANIGAWA Takeshi (80227214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SAITO Isao (90253781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MARUYAMA Koutatsu (20627096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. OSAWA Haruhiko (90294800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ONUMA Hiroshi (00294794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KAWAMURA Ryoichi (90533092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KISHIDA Taro (80304658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. SUYAMA Keiko (50214713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TAKATA Yasunori (20432792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. HENMI Ikuyo (10132458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. SAKURAI Susumu (50375515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TANNO Sakurako (00591819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. YAMAUCHI Kanako (20510283)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 田中守 (00612350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. MATSUMOTO Yoshiteru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. TAMASAKI Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. HEIKE Yuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KAWAKUBO Akihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. KIYOHIDE Tomooka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. NISHIOKA Shinji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. MIYOSHI Noriko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. KINOSHITA Tetsu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. KATI Hiromasa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. Hitsumoto Shinichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. FURUKAWA Shinya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. KAWASAKI Yuri

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. MORI Hiromi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. HIGUCHI Kana

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. Eduardo Campos Alberto

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 西甲介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SUGAHARA Takuya 菅原 卓也

Sugahara Takuya 菅原 卓也

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Co-Researchers

酸性アミノ酸含有ジペプチドの保健機能と作用機構の解明Principal Investigator

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Evaluation of health function and the mode of action of dipeptides containing glutamic acid.Principal Investigator

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Evaluation of health functions of scirpusin B from passion fruit seedsPrincipal Investigator

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Anti-inflammatory effect of hen egg white lysozymePrincipal Investigator

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Effect of collagen on the innate immune system.Principal Investigator

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Studies on the structure-activity relationship of flaxseed lignan, multifunctional physiologically active substancePrincipal Investigator

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Studies on a novel immunostimulation factor in fermented milk.Principal Investigator

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熱変性リゾチームの抗体産生促進活性増強メカニズム解明に関する研究Principal Investigator

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SUGAHARA Takuya 菅原卓也

Sugahara Takuya 菅原卓也