NAKATA Munehiro 中田宗宏

Researcher Number	00266371
Other IDs
Affiliation (based on the past Project Information) *help	2007 – 2011: 東海大学, 工学部, 教授 2002 – 2005: 東海大学, 工学部, 助教授 1997 – 1998: Tokai University, School of Engineering, Associate Professor, 工学部, 助教授 1994 – 1996: 東海大学, 工学部, 講師
Review Section/Research Field	Principal Investigator Structural biochemistry Except Principal Investigator Biological Sciences / Digestive surgery / Structural biochemistry / 内科学一般 / Immunology
Keywords	Principal Investigator MRL / Glycoprotein / Cryoglobulin / Autoimmune / lpr mice / Galactosylation / Oligosaccharide / Immunoglobulin G / Nephropathy / 自己免疫疾患 … More / 糖タンパク質 / クリオグロブリン / 自己免疫 / lprマウス / ガラクトシレーション / 糖鎖 / 免疫グロブリンG / 糸球体腎炎 … More Except Principal Investigator レクチン / 人工糖脂質 / 抗真菌剤 / 糖鎖プローブ / 抗生物質 / HIV / MASP / 化学療法 / 肝内転移 / 肝細胞癌 / 糖鎖構造異常 / IgG / エイズ / Molecular Evolution / Ficolin / Lectin Pathway / Complement / MBL / 自然免疫 / 分子進化 / フィコリン / レクチン経路 / 補体 / oligosaccharide probe / antifungal agent / neoglycolipid / carbohydrate-binding antibiotics / 糖鎖結合性抗生物質 / abnormality in oligosaccharide structures / diagnosis of rheumatoid arthritis / serum test / early-phase rheumatoid arthritis / immunoglobulin G / rheumatoid factor / rheumatoid arthritis / リウマチ診断 / 血清検査 / 早期リウマチ / リウマチ因子 / 慢性関節リウマチ / 血管新生 / APN / 浸潤 / 分子標的治療薬 / 脈管浸潤 / DCP / 肝細胞がん / 治療 / ピロリジン誘導体 / 肝臓外科学 / 予後 / 組織化学 / 自動識別システム / 診断 / 複合糖質 / 肝転移 / 大腸がん / 消化器がん / SIV / MAIDS / アジュバント / ハエ糖脂質 / 遅延型アレルギー反応 / 細胞障害性T細胞 / 細胞性免疫応答 / 糸球体腎炎 / 自己免疫病 / Fasリガンド / Fas抗原 / gld遺伝子 / lpr遺伝子 / IgG糖鎖 / アポトーシス / 糖鎖識別 / 糖蛋白質 / 糖鎖構造 / 抗HIV剤 Less

Development of novel molecular-targeted medicine against aminopeptidase
- Principal Investigator
  
  KARAKO Takashi (TANG Wei)
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo
肝細胞がん特有の進行メカニズムに着目した新規化学療法剤の開発
- Principal Investigator
  
  唐子堯
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Inhibition of intrahepatic metastasis of hepatocellularcarcinoma by novel pyrrolidine derivatives
- Principal Investigator
  
  KARAKO Takashi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo
大腸がん肝転移・リンパ節転移に関わる複合糖質の解明とその組織内自動検出
- Principal Investigator
  
  KARAKO Takashi (唐偉)
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Abnormal glycosylation of renal pathogmic immunoglobulinPrincipal Investigator
- Principal Investigator
  
  NAKATA Munehiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tokai University
Roles of host defense lectin.s in innate immunity
- Principal Investigator
  
  FUJITA Teizo
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  UNIVERCTTY
細胞性免疫を誘導できるヒトに対して安全で強力なアジュバントに関する研究
- Principal Investigator
  
  水落次男
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokai University
自己免疫病と糖鎖構造異常に関する研究
- Principal Investigator
  
  水落次男
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
Analyses and application of the recognition mechanism of carbohydrate structure by carbohydrate-binding antibiotics.
- Principal Investigator
  
  MIZUOCHI Tsuguo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tokai University, School of Engineering
糖鎖結合性抗生物質の糖鎖構造認識機構の解析とその応用
- Principal Investigator
  
  水落次男
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
アポトーシス関連遺伝子をもつリウマチ因子産生マウスにおけるIgG糖鎖異常の解析
- Principal Investigator
  
  水落次男
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokai University
Development of methods for specific detection of oligosaccharide chains of rheumatoid factor in sera from patients with early-phase rheumatoid arthritis.
- Principal Investigator
  
  MIZUOCHI Tsuguo
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  内科学一般
- Research Institution
  Tokai University, School of Engineering
HIV糖鎖の役割と糖鎖に着目したエイズ制圧に関する基礎的研究
- Principal Investigator
  
  MIZUOCHI Tsuguo
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
糖鎖結合性抗生物質の糖鎖構造認識機構の解析とその応用
- Principal Investigator
  
  水落次男
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University

All 2011 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Patent

[Journal Article] Sustained abberant localization of KL-6 mucin and β-catenin at the invasion front of human gastric cancer cells.2011
- Author(s)
  Inagaki Y, Tang W, Xu H, Nakata M, et al.
- Journal Title
  
  Anticancer Research
  
  Volume: 31 Pages: 535-542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390373
[Journal Article] Antitumor activityof extracts and compounds from the skinof the toad Bufo bufo gargarizans Cantor2011
- Author(s)
  Qi F, Li A, Inagaki Y, Kokudo N, Tamura S, Nakata M, Tang W.
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 11(3) Issue: 3 Pages: 342-349
- DOI
  10.1016/j.intimp.2010.12.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390373
[Journal Article] KL-6mucin in metastatic liver cancertissues from primary colorectalcarcinoma2009
- Author(s)
  Zhang K, Tang W, Qu X, Guo Q, InagakiY, Seyama Y, Abe H, Gai R, Kokudo N, Sugawara Y, Nakata M, Makuuchi M. Y, Seyama Y, Abe H, Gai R, Kokudo N, Sugawara Y, Nakata M
- Journal Title
  
  KL-6mucin in metastatic liver cancertissues from primary colorectalcarcinoma.
  
  Volume: 56(93) Pages: 960-963
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390373
[Journal Article] Expression of KL-6 mucin, a human MUC1 mucin, in intrahepatic cholangiocarcinoma and its potential involvement in tumor cell adhesion and invasion2009
- Author(s)
  Xu HL, Inagaki Y, Seyama Y, Sugawara Y, Kokudo N, Nakata M, Wang FS, Tang W.
- Journal Title
  
  Life Sci
  
  Volume: 85(9-10) Issue: 9-10 Pages: 395-400
- DOI
  10.1016/j.lfs.2009.07.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390373
[Journal Article] Clinicopathology of sialomucin : MUC1, particularly KL-6 mucin, ingastrointestinal, hepatic andpancreatic cancers2009
- Author(s)
  Inagaki Y, Xu H, Nakata M, Seyama Y, Hasegawa K, Sugawara Y, Tang W, KokudoN.
- Journal Title
  
  Biosci Trends
  
  Volume: 3(6) Pages: 220-232
- URL
  http://www.biosciencetrends.com/action/downloaddoc.php?docid=258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390373
[Journal Article] Clinicopathology of sialomucin : MUCl, particularly KL-6 mucin, in gastrointestinal, hepatic and pancreatic cancers.2009
- Author(s)
  Inagaki Y, Xu H, Nakata M, Seyama Y, et al.
- Journal Title
  
  Biosci trends. 3
  
  Pages: 220-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390373
[Journal Article] Subcellular localizationof KL-6 mucin in colorectal carcinomacell lines : association withmetastatic potential and cellmorphology2007
- Author(s)
  Guo Q, Tang W, Inagaki Y, Kokudo N, Sugawara Y, Karako H, Nakata M, Makuuchi M
- Journal Title
  
  Oncol Rep 17
  
  Pages: 1057-1060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591578
[Journal Article] KL-6mucin is a useful immunohistochemicalmarker for cholangiocarcinoma2007
- Author(s)
  Tang W, Guo Q, Qu XJ, Inagaki Y, SeyamaY, Midorikawa Y, Gai R, Kokudo N, Sugawara Y, Nakata M, Makuuchi M
- Journal Title
  
  Oncol Rep 17
  
  Pages: 737-741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591578
[Journal Article] KL-6 mucin is a useful immunohistochemical marker for cholangiocarcinoma2007
- Author(s)
  Tang W, 他6名, Kokudo N, Sugawara Y, Nakata M, Makuuchi M
- Journal Title
  
  Oncol Rep 17
  
  Pages: 737-741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591578
[Journal Article] Induction ofapoptosis in human hepatocellularcarcinoma cells by syntheticantineoplaston A102007
- Author(s)
  Qu XJ, Cui SX, Tian Z, Li X, Chen MH, Xu WF, Inagaki Y, Deng YB, Makuuchi M, Nakata M, Tang W
- Journal Title
  
  Anticancer Res 27
  
  Pages: 2427-2431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591578
[Journal Article] Clinical significance of subcellular lacalization of KL-6 mucin in primary colorectal adenocarcannoma and metastatic tissues.2006
- Author(s)
  Guo Q, TANG W, 他4名, Nakata M, 他2名, Makuuchi M
- Journal Title
  
  World J Gastroenterol 12(1)
  
  Pages: 54-59
- Data Source
  KAKENHI-PROJECT-17015010
[Journal Article] Aberrant expression of KL-6 in carcinoma of the ampulla of Vater : Association with cancer progression.2005
- Author(s)
  TANG W, 他4名, Nakata M, 他3名, Makuuchi M
- Journal Title
  
  World J Gastroenterol 11(35)
  
  Pages: 5450-5454
- Data Source
  KAKENHI-PROJECT-17015010
[Journal Article] Des-gamma-Carboxyprothrombin Expression in Cancer And/or Non-Cancer Liver Tissues : Association with Survival of Patients with Resectable Henatocellular Carcinoma2005
- Author(s)
  TANG W, 他7名, Nakata M, Makuuchi M
- Journal Title
  
  Oncol Rep 13(1)
  
  Pages: 25-30
- Data Source
  KAKENHI-PROJECT-17015010
[Journal Article] Histochemical expression of sialoglycoconjugates in carcinoma of the papilla of Vater2005
- Author(s)
  TANG W, 他6名, Nakata M, Makuuchi M
- Journal Title
  
  Hepato -Gastroenterology 52(61)
  
  Pages: 67-71
- Data Source
  KAKENHI-PROJECT-17015010
[Journal Article] Epidermal growth factor-mediated growth control of confluent mammary epithelial cells cultured on artificial basement membrane2005
- Author(s)
  Guo Q, TANG W, 他5名, Nakata M, Fujita-Yamaguchi Y, Makuuchi M
- Journal Title
  
  Int J Mol Med 16(3)
  
  Pages: 395-399
- Data Source
  KAKENHI-PROJECT-17015010
[Journal Article] Sustained abberant localization of KL-6 mucin andβ-catenin at theinvasion front of human gastric cancercells
- Author(s)
  Inagaki Y, Tang W, Xu H, Nakata M, Mafune K, Konishi T, Seto Y, Kokudo N.
- Journal Title
  
  Anticancer Res
  
  Volume: 31(2) Pages: 535-542
- URL
  http://ar.iiarjournals.org/content/31/2/535.long
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390373
[Journal Article] Sialoglycoconjugate expression in primary colorectal cancer and metastatic lymph node tissues.
- Author(s)
  Inagaki Y, TANG W, 他5名, Nakata M, Nagawa H, Makuuchi M
- Journal Title
  
  Hepato-Gastroenterology (In press)
- Data Source
  KAKENHI-PROJECT-17015010
[Patent] 糖結合性ファージ提示抗体の解析方法2004
- Inventor(s)
  中田他6名
- Industrial Property Rights Holder
  学校法人東海大学, 学
- Industrial Property Number
  2004-243198
- Filing Date
  2004-08-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13143204
[Presentation] ANTINEOPLASTONA10 INHIBITS THE GROWTH OF HEPATOMACELLS THROUGH THE INDUCTION OFAPOPTOSIS2008
- Author(s)
  Inagaki Y, Tang W, Qu XJ, Cui SX, LiX, Yuan YX, Tian ZG, Xu WF, Nakata M, Sugawara Y, Kokudo N
- Organizer
  13th World Congress onAdvances in Oncology and 11thInternational Symposium on MolecularMedicine
- Place of Presentation
  Crete, Greece
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19591578
[Presentation] Different expression profile of KL-6mucin in primary liver cancer tissues2008
- Author(s)
  Tang W, Inagaki Y, Xu HL, Seyama Y, Nakata M, Sugawara Y, Kokudo N
- Organizer
  第108回日本外科学会定期学術集会
- Place of Presentation
  長崎, 日本
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19591578
[Presentation] KL-6 mucin as a diagnostic marker for cholangiocarcinoma2007
- Author(s)
  Inagaki Y, Xu HL, Tang W, Nakata M, Sugawara Y, Kokudo N
- Organizer
  China-Japan Joint Medical Workshop on Drug Discoveries and Therapeutics
- Place of Presentation
  中国山東省済南
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19591578
[Presentation] Availability of KL-6 mucin as a tool for discriminating cholangiocarcinoma from hepatocellular carcinoma2007
- Author(s)
  Inagaki Y, Xu HL, Kokudo N, Sugawara Y, Nakata M, Tang W
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会合同大会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19591578
[Presentation] Availability ofKL-6 mucin as a tool fordiscriminating cholangiocarcinomafrom hepatocellular carcinoma2007
- Author(s)
  Inagaki Y, Xu HL, Kokudo N, SugawaraY, Nakata M, Tang W
- Organizer
  Congress of Biochemistry andMolecular Biology 2007 (第30回日本分子生物学会年会・第80回日本生化学会合同大会)
- Place of Presentation
  横浜, 日本
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19591578
[Presentation] KL-6 mucin as adiagnostic marker forcholangiocarcinoma.2007
- Author(s)
  Inagaki Y, Xu HL, Tang W, Nakata M, Sugawara Y, Kokudo N
- Organizer
  China-JapanJoint Medical Workshop on Drug Discoveries and Therapeuticss
- Place of Presentation
  Jinan, China
- Data Source
  KAKENHI-PROJECT-19591578

1. MIZUOCHI Tsuguo (90133149)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. KARAKO Takashi (00313213)

# of Collaborated Projects: 4 results

# of Collaborated Products: 22 results
3. MAKUUCHI Masatoshi (60114641)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. KOKUDO Norihiro (00205361)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. SEKIMIZU Kazuhisa (90126095)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. FUJITA Teizo (20134223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ENDO Yuidii (20117427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IWAKI Daisuke (10315492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAAKMURA Takanori (70183887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. AZUMI Kaoru (90221720)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 高橋実 (00285024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 松下操 (00165812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKATA Munehiro 中田 宗宏

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Abnormal glycosylation of renal pathogmic immunoglobulinPrincipal Investigator

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[Journal Article] Sustained abberant localization of KL-6 mucin and β-catenin at the invasion front of human gastric cancer cells.2011

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[Journal Article] Antitumor activityof extracts and compounds from the skinof the toad Bufo bufo gargarizans Cantor2011

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NAKATA Munehiro 中田宗宏