KURATA Yasutaka 倉田康孝

Researcher Number	00267725
Other IDs
Affiliation (Current)	2025: 金沢医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 金沢医科大学, 医学部, 教授 2014 – 2016: 金沢医科大学, 医学部, 教授 2007 – 2013: School of Medicine, 医学部, Associate Professor 2004 – 2006: Kanazawa Medical University, Associate Professor, 医学部, 助教授 2003: 金沢医科大学, 講師 … More 2003: 金沢医科大学, 医学部, 講師 2003: 金沢医科大学, 医学部・第2生理学教室, 講師 1996 – 2001: 金沢医科大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator General physiology / Basic Section 48020:Physiology-related / Complex systems / Circulatory organs internal medicine / General physiology Except Principal Investigator Circulatory organs internal medicine / Basic Section 48020:Physiology-related / Anesthesiology/Resuscitation studies / Circulatory organs internal medicine / Emergency medicine
Keywords	Principal Investigator 分岐理論 / システム生理学 / 分岐解析 / 非線形力学 / 数理モデル / 生物物理 / 生物・生体工学 / 早期後脱分極 / コンピュータシミュレーション / computer simulations … More / nonlinear dynamical systems / ionic channels / コンピュータ・シミュレーション / 非線形力学系モデル / イオンチャネル / バイオペースメーカー / bifurcation analysis / 再生医学 / 生理学 / 遅延整流K電流 / 不整脈 / モデルデータベース / 心臓自動能 / 心筋細胞モデル / シミュレーション / システム制御 / 異常自動能 / HL-1マウス心筋細胞 / regenerative medicine / bifurcation theory / biological pacemaker / automaticity / human ventricular myocytes / 非線形力学系 / 自動能 / ヒト心室筋細胞 / rate theory / Markovian state models / ion transporters / sinoatrial node / 絶対反応速度論 / 定常マルコフ状態モデル / イオントランスポーター / 洞結節細胞 / HCN4 / ヒトES細胞 / computer simulation / mathematical model / cardiac pacemaker / 再生医療 / 不整脈学 / 心電学 / ヒト心筋モデル / フィジオーム / システム生理 / Na-channel / ATP感受性Kチャネル / 虚血性不整脈 / 血小板活性化因子 / 非線形力学系理論 … More Except Principal Investigator アナフィラキシーショック / Anaphylactic shock / 生理学 / ラット / フィジオーム / 生物物理 / 細胞・組織 / 不整脈 / 血管閉塞法 / 肝循環 / ion channel / T型Caチャンネル / イオンチャンネル / ペースメーカー活性 / ES細胞 / E-C coupling / cardiac muscle / パッチクランプ法 / カルシウム電流 / ストレンゲージ法 / 微小電極法 / 興奮収縮連関 / 心筋 / 肥満細胞 / rat / 循環ショック / 生体シミュレーション / Hepatic microvascular pressure / Double occlusion pressure / Perfused rat livers / Servo-nulling system / Circulatory shock / Microcirculation / Hepatic circulation / 肝類洞 / ラット摘出灌流肝臓 / 肝微小血管圧 / 肝細静脈圧 / 肝血管収縮 / 門脈圧 / 肝微小血管 / エンドトキシンショック / サーボヌルシステム / ミクロピペット法 / 微小循環 / エンドトキシンショッ / Kupffer cell / mast cell / guinea pig / sinusoidal Pressure / isolated perfused liver / hepatic circulation / 血管抵抗 / 摘出灌流肝臓 / アナフィラキシィーショック / クッパー細胞 / モルモット / 肝類洞圧 / 摘出灌流肝 / SNPs / Na^+ channel blockers / ubiquitin-proteasome / atrial fibrillation / 小胞体品質管理機構 / 細胞内トラフィック / ユビキチン化 / HSP70 / Kv1.5 / 蛋白安定化 / Na channel 阻害剤 / ユビキチン・プロテアソーム / 心房細動 / pacemaker / ES cell / Ni非感受性T型Caチャネル / Ni感受性T型Caチャネル / 心筋分化 / 自動能 / simulation / Nkx2.5 / calcium current / Strain gauge / microelectrode / bradykinin / ブラジキニシ / ランプクランプ / ストレゲージ法 / ブラジキニン / calcinm current / strain gange / microeleetrade / adrenomedullin / 膜イオン電流 / ヒト心筋 / 心筋の興奮収縮連関 / イオン電流 / アドレノメデュリン / 脳水分量 / 核磁気共鳴映像法 / 喉頭浮腫 / 脳浮腫 / 出血性ショック / 腸間膜動脈血流量 / 内頚動脈血流量 / 脳組織血流量 / anesthetized rats / c-fos / evans blue dye / edema / brain MRI / vascular permeability / brain blood flow / autoregulation / anaphylactic shock / brain circulation / シミュレーション工学 / 再生医学 / 遺伝子 / 循環器 / パッチクランプ / 遺伝子変異 / 徐脈性不整脈 / 生物学的ペースメーカー / 心筋前駆細胞 / 遺伝子解析 / 先天性徐脈 / eEmax / dtmax / dP / 摘出灌流心臓 / 血液交差灌流 / dP/dt max / βアドレナリン受容体阻害剤 / 冠動脈血流 / 心収縮性 / 血液交叉灌流心臓 / 心アナフィラキシー / 冠血管収縮 / Emax / 血液交差灌流心臓 / 心機能 Less

Elucidation of sustained mechanisms of triggered activity-mediated ventricular tachyarrhythmias
- Principal Investigator
  
  津元国親
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Kanazawa Medical University
分岐解析によるヒト心筋細胞モデルデータベース構築と心臓自動能発生機序の統合的解明Principal Investigator
- Principal Investigator
  
  倉田康孝
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Kanazawa Medical University
Mechanisms of triggered activity in lethal arrhythmias: in silico study
- Principal Investigator
  
  TSUMOTO Kunichika
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Kanazawa Medical University
Theoretical and experimental study of controlling cardiac cell system dynamics using HL-1 mouse cardiomyocytes and a mathematical modelPrincipal Investigator
- Principal Investigator
  
  KURATA Yasutaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Kanazawa Medical University
Insights into pacemaker mechanisms for human stem cell-derived cardiomyocytes with application to biological pacemaker engineeringPrincipal Investigator
- Principal Investigator
  
  KURATA Yasutaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa Medical University
分岐理論に基づくヒト固有心筋自動能の発生機序並びに合理的制御法の解明Principal Investigator
- Principal Investigator
  
  倉田康孝
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kanazawa Medical University
Systematic study on brain circulation during anaphylactic shock
- Principal Investigator
  
  SHIBAMOTO Toshishige
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Kanazawa Medical University
Development of novel mathematical models for human cardiac myocytes based on bifurcation analysis and comparative studyPrincipal Investigator
- Principal Investigator
  
  KURATA Yasutaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa Medical University
Gene analysis for the inherited bradyarrhythmia and characterization of cardiosphere-derived cells to create biological pacemakers
- Principal Investigator
  
  HAYASHI Kenshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kanazawa University
Dynamical properties of mouse ES-cell derived cardiomyocytes during differentiation: insights from bifurcation analysis based on nonlinear dynamical system theoryPrincipal Investigator
- Principal Investigator
  
  KURATA Yasutaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa Medical University
Investigation on cardiac function during anaphylactic shock
- Principal Investigator
  
  SHIBAMOTO Toshishige
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Kanazawa Medical University
Hepatic microvascular pressure during circulatory shock
- Principal Investigator
  
  SHIBAMOTO Toshishige
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kanazawa Medical University
Dynamical mechanisms of pacemaker generation in cardiac myocytes: a comprehensive study based on bifurcation theory with application to biological pacemaker engineeringPrincipal Investigator
- Principal Investigator
  
  KURATA Yasutaka
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa Medical University
Development of a novel thermodynamical model for sinoatrial node pacemaker cells and bifurcation analysis of the model systems in terms of nonlinear dynamics.Principal Investigator
- Principal Investigator
  
  KURATA Yasutaka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  KANAZAWA MEDICAL UNIVERSITY
Establishment of genetically modified biological pacemaker cell based on the in-silico model
- Principal Investigator
  
  IGAWA Osamu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National University Corporation Tottori University
Stabilization of ion channel protein by regulation of proteasome and its application to the individualizing atrial fibrillation.
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National University Corporation Tottori University
Integrative study on hepatic anaphylaxis
- Principal Investigator
  
  SHIBAMOTO Toshishige
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  KANAZAWA MEDICAL UNIVERSITY
Effect of bradykinin on excitation-contraction coupling in excised human atrial muscles
- Principal Investigator
  
  IMANISHI Sunao
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kanazawa Medical University
血小板活性化因子による心筋早期後脱分極の誘発とその発生機序Principal Investigator
- Principal Investigator
  
  倉田康孝
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kanazawa Medical University
Effect of adrenomedullin on excitation-contraction coupling and abnormal automaticity in excised human atrial muscles
- Principal Investigator
  
  IMANISHI Sunao
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kanazawa Medical University
心筋の早期後脱分極発現に対する遅延整流K電流の役割:非線形力学系理論に基づく解明Principal Investigator
- Principal Investigator
  
  倉田康孝
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Kanazawa Medical University

[Journal Article] Theoretical prediction of early afterdepolarization-evoked triggered activity formation initiating ventricular reentrant arrhythmias.2023
- Author(s)
  Tsumoto K, Shimamoto T, Aoji Y, Himeno Y, Kuda Y, Tanida M, Amano A, Kurata Y.
- Journal Title
  
  Comput Methods Programs Biomed.
  
  Volume: 240 Pages: 107722-107722
- DOI
  10.1016/j.cmpb.2023.107722
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06850, KAKENHI-PROJECT-21K06776, KAKENHI-PROJECT-23K28032
[Journal Article] Bifurcations and Proarrhythmic Behaviors in Cardiac Electrical Excitations2022
- Author(s)
  Kunichika Tsumoto, Yasutaka Kurata
- Journal Title
  
  Biomolecules
  
  Volume: 12 Issue: 3 Pages: 459-459
- DOI
  10.3390/biom12030459
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07290, KAKENHI-PROJECT-21K06776
[Journal Article] Multiple Dynamical Mechanisms of Phase-2 Early Afterdepolarizations in a Human Ventricular Myocyte Model: Involvement of Spontaneous SR Ca (2+) Release.2020
- Author(s)
  Kurata Y, Tsumoto K, Hayashi K, Hisatome I, Kuda Y, Tanida M.
- Journal Title
  
  Front Physiol.
  
  Volume: 10 Pages: 1545-1545
- DOI
  10.3389/fphys.2019.01545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08100, KAKENHI-PROJECT-19K07290, KAKENHI-PROJECT-17K09580, KAKENHI-PROJECT-20H04133
[Journal Article] Dynamical mechanisms of phase-2 early afterdepolarizations in human ventricular myocytes: insights from bifurcation analyses of two mathematical models2017
- Author(s)
  Kurata Y, Tsumoto K, Hayashi K, Hisatome I, Tanida M, Kuda Y, Shibamoto T
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 312 Issue: 1 Pages: H106-H127
- DOI
  10.1152/ajpheart.00115.2016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460303, KAKENHI-PROJECT-26460670, KAKENHI-PROJECT-16KT0194, KAKENHI-PROJECT-15KK0302, KAKENHI-PROJECT-16K09767
[Journal Article] Electrophysiological properties of iPS cell-derived cardiomyocytes from a patient with long QT syndrome type 1 harboring the novel mutation M437V of KCNQ12016
- Author(s)
  Sogo T, Morikawa K, Kurata Y, Li P, Ichinose T, Yuasa S, Nozaki D, Miake J, Ninomiya H, Shimizu W, Fukuda K, Yamamoto K, Shirayoshi Y, Hisatome I
- Journal Title
  
  Regenerative Therapy
  
  Volume: 4 Pages: 9-17
- DOI
  10.1016/j.reth.2015.12.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460303, KAKENHI-PROJECT-25461109
[Journal Article] 心筋における異常自動能の発生機序：ヒト心室筋細胞モデルを用いた非線形力学的解析2014
- Author(s)
  倉田康孝、谷田　守、九田裕一、芝本利重
- Journal Title
  
  金沢医科大学雑誌
  
  Volume: 39 Pages: 59-66
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25136720
[Journal Article] MRI reveals edema in larynx (but not brain) during anaphylactic hypotension in anesthetized rats.2013
- Author(s)
  Toyota I, Tanida M, Shibamoto T, Wang M, Kurata Y, Tonami H.
- Journal Title
  
  Allergy Asthma Immunol Res.
  
  Volume: 5 Issue: 6 Pages: 389-396
- DOI
  10.4168/aair.2013.5.6.389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462839
[Journal Article] Effect of hyper- polarization-activated current I_f on robustness of sinoatrial node pacemaking : theoretical study on influence of intracellular Na^+ concentration2013
- Author(s)
  Kurata Y, Hisatome I, Tanida M, Shibamoto T
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 304 Pages: 1337-1351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590266
[Journal Article] A novel mutation in the transmembrane nonpore region of the KCNH2 gene causes severe clinical manifestations of long QT syndrome2013
- Author(s)
  Kurata Y
- Journal Title
  
  Heart Rhythm
  
  Volume: 10 Issue: 1 Pages: 61-7
- DOI
  10.1016/j.hrthm.2012.09.053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590806, KAKENHI-PROJECT-22590808, KAKENHI-PROJECT-23591078, KAKENHI-PROJECT-24790748
[Journal Article] Rat hepatic and splanchnic vascular responses to anaphylactic shock, compared with hemorrhagic or vasodilator-induced shock.2013
- Author(s)
  Zhang W, Shibamoto T, Tanida M, Wang M, Sun L, Kurata Y.
- Journal Title
  
  In Vivo.
  
  Volume: 27 Pages: 485-493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462839
[Journal Article] Effect of hyperpolarization-activated current If on robustness of sinoatrial node pacemaking: theoretical study on influence of intracellular Na+ concentration2012
- Author(s)
  Kurata Y
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 304 Issue: 10 Pages: 61-7
- DOI
  10.1152/ajpheart.00777.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590806, KAKENHI-PROJECT-23590266, KAKENHI-PROJECT-25670110
[Journal Article] Roles of sarcoplasmic reticulum Ca2+ cycling and Na+/Ca2+ exchanger　in sinoatrial node pacemaking: Insights from bifurcation analysis of mathematical models.2012
- Author(s)
  Kurata Y
- Journal Title
  
  American Journal of Physiology (Heart Circ Physiol)
  
  Volume: 302 Issue: 11 Pages: H2285-H2300
- DOI
  10.1152/ajpheart.00221.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590266, KAKENHI-PROJECT-23659112
[Journal Article] Roles of sarcoplasmic reticulum Ca^2+ cycling and Na^+/Ca^2+ exchanger in sinoatrial node pacemaking : insights from bifurcation analysis of mathematical models2012
- Author(s)
  Kurata Y, Hisatome I, Shibamoto T
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 302 Pages: 2285-2300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590266
[Journal Article] Mast cells are not involved in the ischemia-reperfusion injury in perfused rat liver.2011
- Author(s)
  Shibamoto T, Tsutsumi M, Kuda Y, Ohmukai C, Zhang W, Kurata Y
- Journal Title
  
  J Surg Res. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592131
[Journal Article] Reciprocal control of hERG stability by Hsp70 and Hsc70 with implication for restoration of LQT2 mutant stability2011
- Author(s)
  Kurata Y
- Journal Title
  
  Circ Res
  
  Volume: 108 Issue: 4 Pages: 458-68
- DOI
  10.1161/circresaha.110.227835
- NAID
  130002130408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590806, KAKENHI-PROJECT-23390209
[Journal Article] Pulmonary vasoconstrictive and bronchoconstrictive responses to anaphylaxis are weakened via β 2-adrenoceptor activation by endogenous epinephrine in anesthetized rats.2011
- Author(s)
  Zhang W, Shibamoto T, Kuda Y, Ohmukai C, Kurata Y
- Journal Title
  
  Anesthesiology. 114(3)
  
  Pages: 614-623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592131
[Journal Article] Portacaval shunting attenuates portal hypertension and systemic hypotension in rat anaphylactic shock.2011
- Author(s)
  Kamikado C, Shibamoto T, Zhang W, Kuda Y, Ohmukai C, Kurata Y
- Journal Title
  
  J Physiol Sci. 61(2)
  
  Pages: 161-166
- NAID
  10029049928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592131
[Journal Article] Roles of hyperpolarization-activated current I_h in sinoatrial node pacemaking : insights from bifurcation analysis of mathematical models.2010
- Author(s)
  Kurata Y, Matsuda H, Hisatome I, Shibamoto T
- Journal Title
  
  Am J Physiol Heart Circ Physiol 298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590220
[Journal Article] Roles of hyperpolarization-activated current I_f in sinoatrial node pacemaking : Insights from bifurcation analysis of mathematical models2010
- Author(s)
  Kurata Y
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590220
[Journal Article] Effects of pacemaker currents on creation and modulation of human ventricular pacemaker : theoretical study with application to biological pacemaker engineering2007
- Author(s)
  Kurata Y
- Journal Title
  
  Am J Physiol Heart Circ Physiol 292・1
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590192
[Journal Article] Effects of pacemaker currents on creation and modulation of human ventricular pacemaker : theoretical study with application to biological pacemaker engineering.2007
- Author(s)
  Kurata et al.
- Journal Title
  
  American Journal of Physiology (Heart Circ Physiol) 292・1
- Data Source
  KAKENHI-PROJECT-17590192
[Journal Article] Effects of pacemaker currents on creation and modulation of human ventricular pacemaker : theoretical study with application to biological pacemaker engineering.2007
- Author(s)
  Kurata Y
- Journal Title
  
  Am J Physiol Heart Circ Physiol 292(1)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590192
[Journal Article] Dynamical mechanisms of pacemaker generation in I_<K1>-downregulated human ventricular myocytes : insights from bifurcation analyses of a mathematical model.2005
- Author(s)
  Kurata Y, Hisatome I, Matsuda H, Shibamoto T.
- Journal Title
  
  Biophys J 89(4)
  
  Pages: 2865-2887
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590195
[Journal Article] Dynamical mechanisms of pacemaker generation in IK1-downregulated human ventricular myocytes : insights from bifurcation analyses of a mathematical model2005
- Author(s)
  Kurata et al.
- Journal Title
  
  Biophysical Journal 89・4
  
  Pages: 2865-2887
- Data Source
  KAKENHI-PROJECT-17590192
[Journal Article] Dynamical mechanisms of pacemaker generation in I_<K1>-downregulated human ventricular myocytes : insights from bifurcation analyses of a mathematical model2005
- Author(s)
  Kurata Y
- Journal Title
  
  Biophys J 89・4
  
  Pages: 2865-2887
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590192
[Journal Article] Dynamical mechanisms of pacemaker generation in I_<KI>-downregulated human ventricular myocytes : insights from bifurcation analyses of a mathematical model2005
- Author(s)
  Kurata Y, et al.
- Journal Title
  
  Biophys J 89・4
  
  Pages: 2865-2887
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590195
[Journal Article] Dynamical mechanisms of pacemaker generation in IK1-downregulated human ventricular myocytes : insights from bifurcation analyses of a mathematical model.2005
- Author(s)
  Kurata Y
- Journal Title
  
  Biophys J 89(4)
  
  Pages: 2865-2887
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590192
[Journal Article] Roles of L-type Ca2+ and delayed-rectifier K+ currents in sinoatrial node pacemaking : insights from stability and bifurcation analyses of a mathematical model.2004
- Author(s)
  Kurata Y, et al.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 285(6)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590747
[Journal Article] Roles of L-type Ca2+ and delayed-rectifier K+ currents in sinoatrial node pacemaking : insights from stability and bifurcation analyses of a mathematical model2004
- Author(s)
  Kurata Y, et al.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 285(6)
- Data Source
  KAKENHI-PROJECT-15590747
[Journal Article] Roles of L-type Ca2+ and delayed-rectifier K+ currents in sinoatrial node pacemaking : insights from stability and bifurcation analyses of a mathematical model2004
- Author(s)
  Kurata Y, et al.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 285(6)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590746
[Journal Article] Roles of L-type Ca2+ and delayed-rectifier K+ currents in sinoatrial node pacemaking : insights from stability and bifurcation analyses of a mathematical model.2004
- Author(s)
  Kurata Y, et al.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 285(6)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590746
[Journal Article] Roles of L-type Ca^<2+> and delayed-rectifier K^+ currents in sinoatrial node pacemaking : insights from stability and bifurcation analyses of a mathematical model2003
- Author(s)
  Kurata Y, et al.
- Journal Title
  
  Am J Physiol Heart Circ Physiol 285・6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590195
[Journal Article] Roles of L-type Ca^<2+> and delayed-rectifier K^+ currents in sinoatrial node pacemaking : insights from stability and bifurcation analyses of a mathematical model.2003
- Author(s)
  Kurata Y, Hisatome I, Imanishi S, Shibamoto T.
- Journal Title
  
  Am J Physiol Heart Circ Physiol 285(6)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590195
[Presentation] HL-1マウス心房筋細胞における自動能の発生機序：膜クロックとCa2+クロックの役割2024
- Author(s)
  九田裕一、倉田康孝、池田崇之、谷田守、津元国親、芝本利重、米倉秀人
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] 洞結節における生理的自動能の発生機序：数理モデルの分岐解析による膜クロックおよびCa2+クロックの役割2024
- Author(s)
  倉田康孝、津元国親、九田裕一、谷田守
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] Dynamical Mechanisms of Sinoatrial Node Pacemaking: Roles of membrane and Ca2+ clocks determined by bifurcation analyses of a mathematical model2024
- Author(s)
  Yasutaka Kurata, Kunichika Tsumoto, Yuhichi Kuda, Mamoru Tanida
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06850
[Presentation] Mechanisms of automaticity in HL-1 mouse atrial myocytes: roles of the membrane and Ca2+ clocks2024
- Author(s)
  Yuhichi Kuda, Yasutaka Kurata, Kunichika Tsumoto, Mamoru Tanida
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06850
[Presentation] 医工・情報学から明かされる心臓不整脈の発生メカニズム2024
- Author(s)
  津元国親、倉田康孝
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] ヒト洞結節自動能の非線形力学的発生機序：数理モデル細胞の分岐解析による理論的検証2023
- Author(s)
  倉田康孝、津元国親、九田裕一、谷田守
- Organizer
  第32回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] ヒト洞結節自動能の非線形力学的発生機序：数理モデル細胞の分岐解析による理論的検証2023
- Author(s)
  倉田康孝、津元国親、九田裕一、谷田守
- Organizer
  第32回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06850
[Presentation] 第III群抗不整脈薬の催不整脈作用による致死的不整脈の起点としてのEAD誘発撃発活動形成の指向性2023
- Author(s)
  津元国親、島本貴生、青地悠馬、天野晃、倉田康孝
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] 心室不整脈の起点としてのEAD誘発撃発活動形成の指向性2023
- Author(s)
  津元国親、島本貴生、青地悠馬、九田裕一、谷田守、天野晃、倉田康孝
- Organizer
  2023年度　生理学研究所心血管研究会「炎症・免疫系と心血管系の相互作用から切り拓く循環生理機能の解析」
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] 心室性不整脈発症に関与する撃発活動形成の理論的機序： in silico研究2023
- Author(s)
  津元国親、島本貴生、青地悠馬、九田裕一、谷田守、天野晃、倉田康孝
- Organizer
  第32回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] Possible anisotropy-based directivity in EAD-induced triggered activity that leads to reentrant tachyarrhythmias2023
- Author(s)
  津元国親、青地悠馬、島本貴生、姫野友紀子、天野晃、九田裕一、谷田守、倉田康孝
- Organizer
  第69回日本不整脈心電学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06850
[Presentation] EADの発生をきっかけとする致死性不整脈の発生機序：in silico研究2023
- Author(s)
  津元国親、青地悠馬、島本貴生、姫野友紀子、天野晃、九田裕一、谷田守、倉田康孝
- Organizer
  日本生理学会　第100回記念大会
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] Possible anisotropy-based directivity in EAD-induced triggered activity that leads to reentrant tachyarrhythmias2023
- Author(s)
  Kunichika Tsumoto, Takao Shimamoto, Yuma Aoji, Yukiko Himeno, Akira Amano, Yasutaka Kurata.
- Organizer
  第69回日本不整脈心電学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] 心室性不整脈発症に関与する撃発活動形成の理論的機序： in silico研究2023
- Author(s)
  津元国親、島本貴生、青地悠馬、九田裕一、谷田守、天野晃、倉田康孝
- Organizer
  第32回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06850
[Presentation] HL-1マウス心房筋細胞における自動能機序と早期後脱分極の発生2022
- Author(s)
  九田裕一, 倉田康孝, 池田崇之, 谷田　守, 津元国親, 芝本利重, 米倉秀人
- Organizer
  第31回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06850
[Presentation] QT延長症候群2型における早期後脱分極を介した致死性不整脈の発生メカニズム：in silico研究.2022
- Author(s)
  津元国親、島本貴生、青地悠馬、九田裕一、谷田守、天野晃、倉田康孝
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] 一過性外向きK+チャネル電流の抑制：QT延長症候群におけるリエントリー性不整脈発生の予防可能性2022
- Author(s)
  津元国親、島本貴生、青地悠馬、九田裕一、谷田守、姫野友紀子、天野晃、倉田康孝
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] Linking the early afterdepolarization in cardiomyocyte models of long QT syndrome type 2 to reentrant arrhythmia2022
- Author(s)
  Tsumoto K, Shimamoto T, Aoji Y, Kuda Y, Tanida M, Amano A, Kurata Y
- Organizer
  The 39th Congress of The International Union of Physiological Sciences (IUPS2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06850
[Presentation] How early afterdepolarization triggers lethal arrhythmias in long QT syndrome type 2: a computational study2022
- Author(s)
  Tsumoto K, Shimamoto T, Aoji Y, Amano A, Kurata Y
- Organizer
  第67回日本不整脈心電学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06850
[Presentation] 不整脈トリガーは如何にして発生するのか：数理モデル解析からの予測2022
- Author(s)
  津元国親, 島本貴生, 青地悠馬, 九田裕一, 谷田　守, 姫野友紀子, 天野　晃, 倉田康孝
- Organizer
  生理学研究所心血管研究会2022
- Data Source
  KAKENHI-PROJECT-22K06850
[Presentation] Mechanisms of ventricular arrhythmias triggered by the development of EAD: an in silico study2022
- Author(s)
  津元国親、青地悠馬、島本貴生、姫野友紀子、天野晃、九田裕一、谷田守、倉田康孝
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-22K06850
[Presentation] How early afterdepolarization triggers lethal arrhythmias in long QT syndrome type 2: a computational study2022
- Author(s)
  津元国親、島本貴生、青地悠馬、天野晃、倉田康孝
- Organizer
  第68回日本不整脈心電学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] EADの発生を契機とする心室性不整脈の発生機序：in silico研究2022
- Author(s)
  津元国親、島本貴生、青地悠馬、九田裕一、谷田守、姫野友紀子、天野晃、倉田康孝
- Organizer
  第69回中部日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] QT延長症候群2型モデルで発生するスパイラルリエントリーの開始メカニズム：シミュレーション研究からの洞察2022
- Author(s)
  津元国親、島本貴生、青地悠馬、九田裕一、谷田守、天野晃、倉田康孝
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] Inhibition of transient outward K+ current: potential prevention of reentrant arrhythmia developments in long QT syndromes2022
- Author(s)
  Tsumoto K, Shimamoto T, Aoji Y, Kuda Y, Tanida M, Himeno Y, Amano A, Kurata Y
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K06850
[Presentation] Mechanisms of Automaticity and Early Afterdepolarization in HL-1 Mouse Atrial Myocytes2022
- Author(s)
  九田裕一、倉田康孝、池田崇之、谷田　守、津元国親、芝本利重、米倉秀人
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-22K06850
[Presentation] 不整脈トリガーは如何にして発生するのか：数理モデル解析からの予測2022
- Author(s)
  津元国親、島本貴生、青地悠馬、九田裕一、谷田守、姫野友紀子、天野晃、倉田康孝
- Organizer
  生理学研究所心血管研究会2022「比較統合生理学的観点からの循環生理の解析」
- Invited
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] EADの発生を契機とする心室性不整脈の発生機序：in silico研究2022
- Author(s)
  津元国親, 島本貴生, 青地悠馬, 九田裕一, 谷田　守, 姫野友紀子, 天野　晃, 倉田康孝
- Organizer
  第69回中部日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06850
[Presentation] Linking the early afterdepolarization in cardiomyocyte models of long QT syndrome type 2 to reentrant arrhythmia2022
- Author(s)
  Kunichika Tsumoto, Takao Shimamoto, Yuma Aoji, Yuhichi Kuda, Mamoru Tanida, Akira Amano, Yasutaka Kurata.
- Organizer
  The 39th Congress of The International Union of Physiological Sciences (IUPS2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] Dynamical Mechanisms of Human Sinoatrial Node Pacemaking: Roles of sarcolemmal ion channel currents and SR Ca2+ handling determined by bifurcation analyses of a mathematical model2022
- Author(s)
  Kurata Y, Tsumoto K, Kuda Y, Tanida M
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-22K06850
[Presentation] HL-1細胞におけるIK1電流の解析と発現制御2021
- Author(s)
  九田裕一, 倉田康孝, 池田崇之, 谷田　守, 津元国親, 芝本利重, 米倉秀人
- Organizer
  第68回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] Characterization and expression regulation of inward-rectifier K+ channel in HL-1 mouse atrial myocytes.2021
- Author(s)
  Kuda Y, Kurata Y, Ikeda T, Tanida M, Tsumoto K, Shibamoto T, Yonekura H
- Organizer
  第126回日本解剖学会総会・全国学術大会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] 心室不整脈トリガーの発生機序：シミュレーション研究2021
- Author(s)
  津元国親, 島本貴生, 青地悠馬, 天野　晃, 九田裕一, 谷田　守, 倉田康孝
- Organizer
  第68回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] Relations between early afterdepolarizations and ventricular lethal arrhythmias in long QT syndrome: a simulation study2021
- Author(s)
  Tsumoto K, Shimamoto T, Amano A, Kurata Y
- Organizer
  第67回日本不整脈心電学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] Elucidation of mechanisms that trigger torsades de pointes in drug-induced long QT syndrome: a simulation study2021
- Author(s)
  Tsumoto K, Shimamoto T, Amano A, Kuda Y, Tanida M, Kurata Y
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] 心室不整脈トリガーの発生機序：シミュレーション研究.2021
- Author(s)
  津元国親, 島本貴生, 青地悠馬, 天野晃, 九田裕一, 谷田守, 倉田康孝
- Organizer
  第68回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-21K06776
[Presentation] Cluster networks consisting of early afterdepolarization-evoked myocytes could cause reentrant arrhythmias in human ventricular tissue.2021
- Author(s)
  Shimamoto T, Tsumoto K, Kurata Y, Amano A
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] Dynamical mechanisms of human sinoatrial node pacemaking: Insights from bifurcation analysis of a mathematical model.2021
- Author(s)
  Kurata Y, Tsumoto K, Hisatome I
- Organizer
  第67回日本不整脈心電学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] HL-1マウス心房筋細胞におけるIK1電流の動態・特性の解析と発現制御2021
- Author(s)
  九田裕一,倉田康孝,池田崇之,谷田　守,津元国親,芝本利重,米倉秀人
- Organizer
  第98回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] Ionic mechanisms of pacemaker activity in HL-1 mouse cardiomyocytes2020
- Author(s)
  Kuda Y, Kurata Y, Ikeda T, Tanida M, Tsumoto K, Shibamoto T, Yonekura H
- Organizer
  第97回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] ヒト心室筋細胞における早期後脱分極の発生機序と合理的制御法の非線形力学的解析2020
- Author(s)
  倉田康孝、津元国親、九田裕一、谷田　守
- Organizer
  第67回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] Controlling development of phase-2 early afterdepolarizations in human ventricular myocytes of long QT syndromes：A theoretical study using bifurcation analyses of two mathematical models2020
- Author(s)
  Kurata Y, Tsumoto K, Hisatome I, Kuda Y, Tanida M
- Organizer
  第97回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] ヒト心筋細胞の早期後脱分極応答に起因した不整脈トリガー：in silico研究2020
- Author(s)
  津元国親，島本貴生，天野晃，九田裕一，谷田守，倉田康孝
- Organizer
  第67回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] HL-1マウス心筋細胞を用いた自動能機序の解明2020
- Author(s)
  九田裕一,倉田康孝,池田崇之,谷田　守,津元国親,芝本利重,米倉秀人
- Organizer
  第67回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] Development of fatal arrhythmias mediating subcellular Na+ channel expression changes：in silico study2020
- Author(s)
  Tsumoto K, Ashihara T, Naito N, Shimamoto T, Amano A, Kurachi Y, Kuda Y, Tanida M, Kurata Y
- Organizer
  第97回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] Distinct dynamical mechanisms of phase-2 early afterdepolarizations in human ventricular myocyte models: Insights from slow-fast decomposition analysis2019
- Author(s)
  Kurata Y, Tsumoto K, Hisatome I
- Organizer
  第66回日本不整脈心電学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] 心筋Na+チャネルの細胞内分布変化が興奮伝播に及ぼす影響について：in silico研究2019
- Author(s)
  津元国親、芦原貴史、内藤成美、島本貴生、天野　晃、倉智嘉久、倉田康孝
- Organizer
  第28回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] ヒト心室筋細胞における早期後脱分極の発生機序とその合理的制御法の非線形力学的解析2019
- Author(s)
  倉田康孝、津元国親、九田裕一、谷田　守
- Organizer
  第28回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07290
[Presentation] Distinct dynamical mechanisms underlie the development of phase 2 early afterdepolarizations in human ventricular myocyte models for long QT syndromes2017
- Author(s)
  Kurata Y, Tsumoto K, Hisatome I, Tanida M, Kuda Y, Shibamoto T
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2017-03-30
- Data Source
  KAKENHI-PROJECT-26460303
[Presentation] Mechanisms of sinoatrial node pacemaking: novel insights into roles of the pacemaker current If from bifurcation analysis of mathematical models2016
- Author(s)
  Kurata Y, Hisatome I, Shibamoto T
- Organizer
  The 2016 International Symposium on Nonlinear Theory and its Applications (NOLTA2016)
- Place of Presentation
  ニューウェルシティー湯河原（神奈川県湯河原市）
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460303
[Presentation] Dynamical mechanism of early afterdepolarization induced by administration of class III antiarrhythmic agents2016
- Author(s)
  Tsumoto K, Kurata Y, Kurachi Y
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26460303
[Presentation] Brain blood flow during anaphylactic hypotension in anesthetized rats2016
- Author(s)
  Shibamoto T, Wang M, Kuda Y, Tanida M, Kurata Y
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）.
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25462839
[Presentation] ヒト心室筋細胞モデルにおける早期後脱分極の再現性とその非線形力学的機序2016
- Author(s)
  倉田康孝、谷田　守、九田裕一、久留一郎、芝本利重
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-26460303
[Presentation] Distinct mechanisms underlie phase 2 early afterdepolarizations in human ventricular myocyte models of long QT syndromes2016
- Author(s)
  Kurata Y, Hisatome I
- Organizer
  第63回日本不整脈心電学会学術大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-07-16
- Data Source
  KAKENHI-PROJECT-26460303
[Presentation] Dynamical mechanisms of phase 2 early afterdepolarizations in long QT syndromes: Insights from slow-fast decomposition analysis of mathematical models for human ventricular myocytes2015
- Author(s)
  Kurata Y, Hisatome I
- Organizer
  第30回日本不整脈学会学術大会・第32回日本心電学会学術集会合同学術大会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-07-30
- Data Source
  KAKENHI-PROJECT-26460303
[Presentation] 心筋細胞における早期後脱分極生成機序解明のための数理解析手法の提案2015
- Author(s)
  津元国親, 倉田康孝, 倉智嘉久
- Organizer
  第54回日本生体医工学会大会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-05-09
- Data Source
  KAKENHI-PROJECT-26460303
[Presentation] Electrophysiological properties of iPS cell-derived cardiomyocytes from a patient with long QT syndrome type 1 harboring a novel mutation of KCNQ12015
- Author(s)
  Kurata Y, Li P, Morikawa K, Miake J, Yamamoto K, Shirayoshi Y, Hisatome I
- Organizer
  第30回日本不整脈学会学術大会・第32回日本心電学会学術集会合同学術大会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-07-29
- Data Source
  KAKENHI-PROJECT-26460303
[Presentation] Dynamical mechanisms of early afterdepolarizations in long QT syndromes: Insights from slow-fast decomposition analyses for human ventricular myocyte models2015
- Author(s)
  倉田康孝、谷田　守、九田裕一、久留一郎、芝本利重
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場・展示場（兵庫県神戸市）
- Year and Date
  2015-03-22
- Data Source
  KAKENHI-PROJECT-26460303
[Presentation] Dynamical mechanisms of early afterdepolarizations in long QT syndromes : insights from bifurcation analysis of mathematical models for human ventricular myocytes2014
- Author(s)
  Kurata Y, Hisatome I, Tanida M, Shibamoto T
- Organizer
  The 91st Annual Meeting of The Physiological Society of Japan
- Place of Presentation
  Kagoshima(J Physiol Sci 64 (Suppl 1): S180)
- Data Source
  KAKENHI-PROJECT-23590266
[Presentation] Dynamical mechanisms of early afterdepolarizations in long QT syndromes: Insights from bifurcation analyses of mathematical models for human ventricular myocytes2014
- Author(s)
  倉田康孝、久留一郎、芝本利重
- Organizer
  第31回日本心電学会学術集会
- Place of Presentation
  ザ・プリンスパークタワー東京（東京都港区）
- Year and Date
  2014-07-24
- Data Source
  KAKENHI-PUBLICLY-25136720
[Presentation] Effect of hyperpolarization-activated current I_f on robustness of sinoatrial node pacemaking : theoretical study in connection with intracellular Na^+ concentration changes2013
- Author(s)
  Kurata Y, Hisatome I, Shibamoto T
- Organizer
  The 90th Annual Meeting of The Physiological Society of Japan
- Place of Presentation
  Tokyo(J Physiol Sci 63 (Suppl 1): S178)
- Data Source
  KAKENHI-PROJECT-23590266
[Presentation] Effect of hyperpolarization-activated current If on robustness of sinoatrial node pacemaking: theoretical study in connection with intracellular Na+ concentration changes.2013
- Author(s)
  Kurata Y
- Organizer
  The 90th annual meeting of the physiological society of Japan
- Place of Presentation
  Tokyo, Japan (Tower Hall Funabori)
- Data Source
  KAKENHI-PROJECT-23590266
[Presentation] アナフィラキシーショック時に脳浮腫はみられるか？　-ラットMRIでの検討-2013
- Author(s)
  豊田一郎、芝本利重、谷田守、王墨飛、倉田康孝、利波久雄
- Organizer
  第23回日本病態生理学会大会
- Place of Presentation
  東京、慈恵医科大学
- Data Source
  KAKENHI-PROJECT-25462839
[Presentation] Roles of sarcoplasmic reticulum Ca^2+ clock and Na^+/Ca^2+ exchanger in sinoatrial node pacemaking : Insights from bifurcation analysis of mathematical models(Intracellular Ca clock and cell excitation)2012
- Author(s)
  Kurata Y, Hisatome I, Shibamoto T
- Organizer
  The 89th Annual Meeting of The Physiological Society of Japan
- Place of Presentation
  Matsumoto(62(Suppl 1): S18)
- Data Source
  KAKENHI-PROJECT-23590266
[Presentation] 孤立性心房細動に認められる遺伝子異常とその意義2012
- Author(s)
  林研至,藤野陽,倉田康孝,山岸正和
- Organizer
  he 27th Annual Meeting of the Japanese Heart Rhythm Society
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2012-07-06
- Data Source
  KAKENHI-PROJECT-22590806
[Presentation] 過分極活性化陽イオンチャネル電流の洞結節細胞ロバスト性への影響:モデル細胞の分岐構造解析による理論的検証2012
- Author(s)
  倉田康孝, 久留一郎, 芝本利重
- Organizer
  第29回日本心電学会学術集会
- Place of Presentation
  千葉(日本心電学会誌・心電図, 32(Suppl 5): S-5-172)
- Data Source
  KAKENHI-PROJECT-23590266
[Presentation] 血液交叉灌流系を用いた心アナフィラキシーの病態解明:心収縮性と冠血流への影響2011
- Author(s)
  倉田康孝(芝本利重)
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  (誌上発表)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-20592131
[Presentation] 洞結節自動能の発現における筋小胞体Ca^<2+>クロックおよびNa/Ca交換機構の役割:モデルシステムの分岐構造解析による検証2011
- Author(s)
  張偉、倉田康孝、久留一郎、芝本利重
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  横浜
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-20590220
[Presentation] 洞結節自動能の発現におけるNa/Ca交換体および筋小胞体Caクロックの役割:モデルシステムの分岐構造解析による検証2011
- Author(s)
  倉田康孝, 久留一郎, 芝本利重
- Organizer
  第28回日本心電学会学術集会
- Place of Presentation
  福岡(日本心電学会誌・心電図, 31(Suppl 4): 298)
- Data Source
  KAKENHI-PROJECT-23590266
[Presentation] Characterization of Compound Heterozygosity for Mutations R269W in KCNH2 and P1824A in SCN5A Associated with Long QT Syndrome and Sinus Node Dysfunction2011
- Author(s)
  Kenshi Hayashi, Noboru Fujino, Yasutaka Kurata, Masakazu Yamagishi
- Organizer
  ACC.11 60th Annual Scientific Session
- Place of Presentation
  Morial Convention Center (USA)
- Year and Date
  2011-04-05
- Data Source
  KAKENHI-PROJECT-22590806
[Presentation] Genetic analysis for the inherited bradyarrhythmia2010
- Author(s)
  林研至,藤野陽,倉田康孝,山岸正和
- Organizer
  The 25th Annual Meeting of the Japanese Heart Rhythm Society / Symposium
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-22590806
[Presentation] 洞結節自動能の発現における細胞内Ca^<2+>動態の役割:洞結節細胞モデルの分岐構造解析による理論的検証2010
- Author(s)
  倉田康孝
- Organizer
  第27回日本心電学会学術集会
- Place of Presentation
  iichiko総合文化センター(大分)
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-20590220
[Presentation] 洞結節自動能の発現における細胞内Ca^<2+>動態の役割:洞結節細胞モデルの分岐構造解析による理論的検証2010
- Author(s)
  倉田康孝、久留一郎、芝本利重
- Organizer
  第27回日本心電学会学術集会
- Place of Presentation
  大分(iichiko総合文化センター)
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-20590220
[Presentation] Roles of hyperpolarization-activated current I_h in sinoatrial node pacemaking : insights from bifurcation analysis of mathematical models.2009
- Author(s)
  Kurata Y, Matsuda H, Hisatome I, Shibamoto T
- Organizer
  36^<th> International congress of physiological sciences (IUPS2009)
- Place of Presentation
  京都(国立京都国際会館)
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-20590220
[Presentation] Roles of hyperpolarization-activated current I_h in sinoatrial node pacemaking : Insights from bifurcation analysis of mathematical models2009
- Author(s)
  倉田康孝
- Organizer
  36^<th> International congress of physiological sciences(IUPS2009)
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-20590220
[Presentation] 洞結節自動能の発現維持における過分極活性化陽イオンチャネル電流の役割 : 洞結節細胞モデルの分岐構造解析による検証2008
- Author(s)
  倉田康孝
- Organizer
  第25回日本心電学会学術集会
- Place of Presentation
  新潟(朱鷺メッセ)
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-20590220
[Presentation] 洞結節自動能の発現維持における過分極活性化陽イオンチャネル電流の役割:洞結節細胞モデルの分岐構造解析による検証2008
- Author(s)
  倉田康孝、松田裕之、久留一郎、芝本利重
- Organizer
  第25回日本心電学会学術集会
- Place of Presentation
  新潟(朱鷺メッセ)
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-20590220
[Presentation] Dynamical mechanisms of early afterdepolarizations in long QT syndromes: insights from bifurcation analysis of mathematical models for human ventricular myocytes
- Author(s)
  Kurata Y, Hisatome I, Tanida M, Shibamoto T
- Organizer
  The 91st Annual Meeting of the physiological society of Japan
- Place of Presentation
  鹿児島大学・郡元キャンパス（鹿児島市）
- Data Source
  KAKENHI-PUBLICLY-25136720
[Presentation] QT延長症候群における早期後脱分極発現の力学的機序：ヒト心室筋細胞モデルの分岐構造解析による検証
- Author(s)
  倉田　康孝、久留一郎、谷田　守、芝本利重
- Organizer
  第30回日本心電学会学術集会
- Place of Presentation
  青森市文化会館（青森市）
- Data Source
  KAKENHI-PUBLICLY-25136720
[Presentation] Dynamical mechanisms of early afterdepolarizations in long QT syndromes: insights from bifurcation analysis of mathematical models for human ventricular myocytes
- Author(s)
  Kurata Y, Hisatome I, Tanida M, Shibamoto T
- Organizer
  The 91st Annual Meeting of the physiological society of Japan
- Place of Presentation
  鹿児島大学・郡元キャンパス（鹿児島市）
- Data Source
  KAKENHI-PROJECT-23590266
[Presentation] Dynamical mechanisms of early afterdepolarizations in long QT syndromes: insights from bifurcation analyses of mathematical models for human ventricular myocytes
- Author(s)
  Kurata Y, Hisatome I, Tanida M, Shibamoto T
- Organizer
  2nd HDP International Symposium 『Multi-Level Systems Biology』
- Place of Presentation
  明治安田生命ビルMy Plazaホール（東京都千代田区）
- Data Source
  KAKENHI-PUBLICLY-25136720
[Presentation] QT延長症候群における早期後脱分極発現の力学的機序：ヒト心室筋細胞モデルの分岐構造解析による検証
- Author(s)
  倉田康孝、久留一郎、谷田　守、芝本利重
- Organizer
  第30回日本心電学会学術集会
- Place of Presentation
  青森市文化会館（青森市）
- Data Source
  KAKENHI-PROJECT-23590266

1. SHIBAMOTO Toshishige (90178921)

# of Collaborated Projects: 9 results

# of Collaborated Products: 29 results
2. TSUMOTO Kunichika (70353331)

# of Collaborated Projects: 4 results

# of Collaborated Products: 50 results
3. IMANISHI Sunao (90108689)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. IGAWA Osamu (80252857)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. HISATOME Ichiro (60211504)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TANIGUCHI Sinn-ici (30304207)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MORISAKI Takayuki (30174410)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 九田裕一 (50566916)

# of Collaborated Projects: 2 results

# of Collaborated Products: 26 results
9. HAYASHI Kenshi (00422642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. FUJINO Noboru (40361993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. YAMAGISHI Masakazu (70393238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. HIGASHIDA Haruhiro (30093066)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SAKAMOTO Yuichiro (70467108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TONAMI Hisao (70139773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. OGURA Toshitsugu (10329378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MIAKE Junichiro (40372677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NINOMIYA Haruaki (80212124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TSUCHIDA Hideaki (20155394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TAKANO Hiromichi (70410313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KURATA Yasutaka 倉田 康孝

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

分岐解析によるヒト心筋細胞モデルデータベース構築と心臓自動能発生機序の統合的解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Theoretical and experimental study of controlling cardiac cell system dynamics using HL-1 mouse cardiomyocytes and a mathematical modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Insights into pacemaker mechanisms for human stem cell-derived cardiomyocytes with application to biological pacemaker engineeringPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

分岐理論に基づくヒト固有心筋自動能の発生機序並びに合理的制御法の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel mathematical models for human cardiac myocytes based on bifurcation analysis and comparative studyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dynamical properties of mouse ES-cell derived cardiomyocytes during differentiation: insights from bifurcation analysis based on nonlinear dynamical system theoryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dynamical mechanisms of pacemaker generation in cardiac myocytes: a comprehensive study based on bifurcation theory with application to biological pacemaker engineeringPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel thermodynamical model for sinoatrial node pacemaker cells and bifurcation analysis of the model systems in terms of nonlinear dynamics.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

KURATA Yasutaka 倉田康孝