HISATOME Ichiro 久留一郎

Researcher Number	60211504
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2021 – 2023: 鳥取大学, 医学部, 特任教員 2008 – 2022: 鳥取大学, 医学(系)研究科(研究院), 教授 2020: 鳥取大学, 医学部, 教授 2015 – 2016: 鳥取大学, 医学系研究科, 教授 2009 – 2012: Tottori University, 大学院・医学系研究科, 教授 … More 2008: Tottori University, 医学系研究科, 教授 2006 – 2007: 鳥取大学, 大学院・医学系研究科, 教授 2005 – 2006: 鳥取大学, 大学院医学系研究科, 教授 2004: Tottori University, Graduate School of Medical Science, Professor, 大学院・医学系研究科, 教授 2003: 鳥取大学, 大学院・医学系研究科, 教授 1998 – 2002: Tottori University, The 1st Department of Medicine, Associate Professor, 医学部, 助教授 1997: 鳥取大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine / General physiology / Basic Section 53020:Cardiology-related / Cardiovascular medicine Except Principal Investigator Plastic surgery / Circulatory organs internal medicine / Basic Section 53020:Cardiology-related / Cardiovascular medicine / Endocrinology … More / Basic Section 58080:Gerontological nursing and community health nursing-related / Basic Section 56070:Plastic and reconstructive surgery-related / Urology / Endocrinology / Circulatory organs internal medicine / Emergency medicine Less
Keywords	Principal Investigator Kv1.5 / HSP70 / ion channel / iPS cell / HCN4 / iPS細胞 / iPS / atrial fibrillation / 細胞内輸送 / イオンチャンネル … More / ユビキチン化 / AMP deaminase / 熱ショック蛋白 / ペースメーカ細胞 / ヒトiPS細胞 / 自動能 / イオンチャネル / ES細胞 / ペースメーカ / feature value / sinus nodal cell / machine learning / 特徴量 / 形態 / 機械学習 / 洞結節細胞 / 深層学習 / SAN cell / automaticity / deep learning / sinoatrial node / 幹細胞 / 刺激伝導系細胞 / ペースメーカ幹細胞 / human / pacemaker cell / isl1 / progenitor / biological pacemaker / geranyl geranyl acetone / stabilization / Hsp70 / CHIP / ゴルジ体 / 小胞体 / シャペロン誘導薬 / Kv1.5チャンネル / SNPs / Na^+ channel blockers / ubiquitin-proteasome / 小胞体品質管理機構 / 細胞内トラフィック / 蛋白安定化 / Na channel 阻害剤 / ユビキチン・プロテアソーム / 心房細動 / T型Caチャンネル / ペースメーカー活性 / Na^+channel blocker / degradation / proteasome / ubiquitin / 再生 / Na^+ channel阻害剤 / プロテアソーム / human heat / myosin heary chain / Ischemic preconditioning / ミオシン重鎖 / AMP deaminase family / AMP deaminase、 / ヒト心臓 / myosin heavy chain / Ischemic peconditioning / hskm1 / hH1 / cysteine 373 / p-loop region / Na channel alpha subunit / reperfusion injury / システイン / S-S結合 / ATP感受性Kチャンネル / 酸化還元 / cysteine^<373> / 虚血再潅流障害 / Cysteine^<373> / Na^+ channel α-subunit / 虚血再灌流障害 / 疾患iPS細胞 / LQT / LQT1 / 疾患iiPS / ヒトＥＳ細胞 / HCN4搭載BACベクター / ヒトES細胞 / pacemaking cells / human ES cells / 細胞移植 / 房室ブロックモデル / 生物学的ペースメーカ … More Except Principal Investigator 再生医療 / 脂肪幹細胞 / 乳房再建 / プロテアソーム / ユビキチン / 甲状腺 / 心房細動 / 心臓 / 脂肪由来幹細胞 / 血管新生 / 自動能 / THYROID / ANAPLASTIC CARCINOMA / PROTEASOME / UBIQUITIN / 未分化癌 / 再生医学 / インスリン抵抗性 / 拡張不全 / ＫＤＢデータベース / 尿酸 / 人工知能 / フレイルチェック / レセプト / 基本チェックリスト / ライフスタイル / 低尿酸血症 / 慢性腎臓病 / 健診受診率 / フレイル / 健康診断 / 介護予防 / KDBデータベース / 脂肪注入 / 形態保持 / 大網 / 脂肪組織由来幹細胞 / マウス / 血管内皮細胞 / 線維芽細胞 / 心臓常在マクロファージ / 尿酸塩結晶 / 常在マクロファージ / 高尿酸血症 / inflammasome / monosodium urate / NLRP3 inflammsome / macrophage / gout / Kv1.5 channel / heat shock protein 70 / K efflux / 尿酸結晶 / Heat shock protein / atrial fibrillation / Monosodium urate / NLRP3 inflammasome / Kv1.5 / 再建外科学 / 移植・再生医療 / 皮下脂肪組織由来幹細胞 / 脂肪組織由来幹細胞移植 / 血管新生作用 / 下肢虚血 / 脱分化脂肪細胞 / 排尿低活動 / 排尿筋低活動 / 生理学 / 排尿機能 / 高血圧 / アルドステロン / 心不全 / 選別分取 / イオンチャネル / Ifチャネル / HCN4 / ヒトES/iPS細胞 / ペースメーカ細胞 / 脂肪 / 移植 / 虚血 / 多血小板血漿 / 血流改善 / 下肢虚血モデル / 分化誘導能 / 細胞増殖能 / 多血小板血漿(PRP) / 脂肪組織由来幹細胞(ADSCs) / WD REPEAT PROTEIN 1 / 癌 / 抗癌剤 / pacemaker / ion channel / ES cell / Ni非感受性T型Caチャネル / Ni感受性T型Caチャネル / 心筋分化 / simulation / Nkx2.5 / T型Caチャンネル / イオンチャンネル / ペースメーカー活性 / ES細胞 / Tet onシステム / プロテアソーム活性化因子 / proteolysis / ATP-sensitive K channel / proteasome / ubiquitin / long QT / ランゲンドルク灌流 / ATP依存的 / 細胞内輸送 / チャネル蛋白 / 蛋白分解 / ユビキチン・プロテアソーム / K^+ channel / QT延長症候群 / subacute thyroiditis / Graves' disease / anti-pendrin antibody / subacue　thyroiditis / painless thyroiditis / Hashimoto thyroiditis / Graves disease / Immunopercipitation / pendrin / ヨード輸送体 / ELISA / バセドウ病 / 橋本病 / 陰イオン交換体 / イオン輸送体 / ペンドリン / ヨード / 血管再生 / 幹細胞 / 動脈硬化 / 脂肪細胞 / CHIP / Hsc70 / Hsp70 / 分子シャペロン / HERG / LQT2 / 難治性皮膚潰瘍 / 細胞培養シート / 間葉系細胞 / インスリン抗性 / 糖代謝異常 / IMP / 肺障害 / AMP deaminase / 虚血再潅流 / イノシン / AMPデアミナーゼ / 虚血再潅流障害 / 人工神経 / 神経血管網 / 神経再生 / 培養シート / 血管内皮前駆細胞 Less

Deep learning-based identification of sinoatrial node-like pacemaker cells from SHOX2/HCN4 double positive cells differentiated from human iPS cellsPrincipal Investigator
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Tottori University
Trial of Breast Reconstruction Using large omentum and Adipose-Derived Stem Cells
- Principal Investigator
  
  YAGI Shunjiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Tottori University
健診・医療・介護一体型ビッグデータの推移から介護予防対象者を把握する指標の探索
- Principal Investigator
  
  浜田紀宏
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58080:Gerontological nursing and community health nursing-related
- Research Institution
  Tottori University
A study of the novel molecular mechanism of atrial fibrillation induced by cardiac resident macrophages in hyperuricemia
- Principal Investigator
  
  TSUNETO Motokazu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Tottori University
Kv1.5 channel mediates monosodium urate-induced activation of NLRP3 inflammasome in macrophages and arrhythmogenic effects of urate on cardiomyocytes
- Principal Investigator
  
  LI Peili
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Tottori University
Development of progenitors of bioogical pacemaker from human iPS cellsPrincipal Investigator
- Principal Investigator
  
  Hisatome Ichiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Tottori University
Adipose-derived stem cell sheet transplantation therapy for detrusor underactivity
- Principal Investigator
  
  TAKENAKA Atsushi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Tottori University
Elucidation of the mechanism of adipose stem cells for Attempt of new breast reconstruction procedure
- Principal Investigator
  
  SUYAMA Yoshiko
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Tottori University
A trial in breast reconstruction surgery using platelet rich plasma and adipose derived stem cells
- Principal Investigator
  
  Yagi Shunjiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Tottori University
Evaluation of cardiac automaticity using human cardiac pacemaking cells derived from human embryonic stem/ induced pluripotent stem cells
- Principal Investigator
  
  Morikawa Kumi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Tottori University
Establishment of measurement and clinical indication of anti pendrin antibody
- Principal Investigator
  
  YOSHIDA Akio
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Tottori University
Stabilization of KvLQT1 by Hsp70 in differentiiated cardiomyocytes derived from LQT1 iPS cellsPrincipal Investigator
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Tottori University
New treatment for left ventricular diastolic failure
- Principal Investigator
  
  Ogino Kazuhide
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Tottori University
Establishment of human pluripotent stem cell-derived pace-making cells using physiological approach and its application to the regenerative medicinePrincipal Investigator
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Tottori University
Investigation of fundamental information of angiogenic therapy using adipose-derived regenerative cell
- Principal Investigator
  
  YAMAMOTO Yasutaka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Tottori University
熱ショック蛋白のHERGチャネル成熟化機構を用いたLQT2の新しい診断と治療
- Principal Investigator
  
  IGAWA Osamu
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tottori University
New therapy for diastolic heart failure from the standpoint of insulin resistance
- Principal Investigator
  
  OGINO Kazuhide
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tottori University
Establishment of ES cell-derived biological pacemaker using ion channel and its application to bradycardia arrhythmiasPrincipal Investigator
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tottori University
Development of the treatment for intractable skin ulcer using monolayered mesenchymal cell sheets
- Principal Investigator
  
  SUYAMA Yoshiko
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Plastic surgery
- Research Institution
  Tottori University
Mechanism on Hsp70-induced stabilization of ion channel and its application to the treatment for atrial fibrillationPrincipal Investigator
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tottori University
血管内皮前駆細胞培養シートによるハイブリット型血管網付き人工神経の開発
- Principal Investigator
  
  NAKAYAMA Bin
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Plastic surgery
- Research Institution
  Tottori University
reperfusion injuryによる心臓・肺障害の機序の解明と治療法の開発
- Principal Investigator
  
  OGINO Kazuhide
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Emergency medicine
- Research Institution
  Tottori University
Establishment of genetically modified biological pacemaker cell based on the in-silico model
- Principal Investigator
  
  IGAWA Osamu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National University Corporation Tottori University
Stabilization of ion channel protein by regulation of proteasome and its application to the individualizing atrial fibrillation.Principal Investigator
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National University Corporation Tottori University
The Development of novel anticancer drugs for anaplastic thyroid carcinoma by collaboration of medicine and engineering
- Principal Investigator
  
  TANIGUCHI Shin-ichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  National University Corporation Tottori University
Mechanisms on the degradation of ion channel proteins and their modification by antiarrythmic agentsPrincipal Investigator
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Department of Cardiovascular Medicine, Tottori University Faculty of Medicine
The Development of novel therapeutic strategy for anaplastic thyroid carcinoma by manipulating the ubiquitin-proteasome activity
- Principal Investigator
  
  TANIGUCHI Shin-ichi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Tottori University
Novel mechanism on the ischemic preconditioning : Role of AMP deaminase family for adenosine productionPrincipal Investigator
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tottori University
Mechanism of long QT syndrome ; Proteasomal degradation of ion channel
- Principal Investigator
  
  CHIAKI Shigemasa
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tottori University Faculty of Medicine
Mechanisms on the reperfusion arrythmias and the protection from reperfusion arrythmias : Redox reguration of the cardiac ion channelsPrincipal Investigator
- Principal Investigator
  
  HISATOME Ichiro, 井川修
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tottori University Faculty of Medicine

[Book] Heart View2013
- Author(s)
  久留一郎
- Total Pages
  5
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-23659112
[Book] 心血管疾患診療のエクセレンス2008
- Author(s)
  久留一郎
- Publisher
  日本医師会
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Effects of Conditioned Medium of Adipose-Derived Stem Cells Exposed to Platelet-Rich Plasma on the Expression of Endothelial Nitric Oxide Synthase and Angiogenesis by Endothelial Cells2023
- Author(s)
  Morita Maki、Suyama Yoshiko、Notsu Tomomi、Fukuoka Kohei、Ikuta Kento、Kanayama Haruka、Umeda Ryunosuke、Teraoka Shogo、Minato Hiroyuki、Ninomiya Haruaki、Tsuneto Motokazu、Shirayoshi Yasuaki、Hisatome Ichiro、Yagi Shunjiro
- Journal Title
  
  Annals of Plastic Surgery
  
  Volume: 90 Issue: 2 Pages: 171-179
- DOI
  10.1097/sap.0000000000003368
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-20K09865, KAKENHI-PROJECT-22K06979
[Journal Article] SHOX2 refines the identification of human sinoatrial nodal cell population in the in vitro cardiac differentiation.2022
- Author(s)
  Wakimizu T, Morikawa K, Fukumura K, Yuki T, Adachi T, Kurata Y, Miake J, Hisatome I, Tsuneto M, Shirayoshi Y.
- Journal Title
  
  Regen Ther.
  
  Volume: 21 Pages: 239-249
- DOI
  10.1016/j.reth.2022.07.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12623, KAKENHI-PROJECT-20K20662, KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-20K08423, KAKENHI-PROJECT-22K06979
[Journal Article] α1-Adrenergic receptor mediates adipose-derived stem cell sheet-induced protection against chronic heart failure after myocardial infarction in rats2022
- Author(s)
  Horie H, Hisatome I, Kurata Y, Yamamoto Y, Notsu T, Adachi M, Li P, et al
- Journal Title
  
  Hypertension research
  
  Volume: 45 Issue: 2 Pages: 283-291
- DOI
  10.1038/s41440-021-00802-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08074, KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-21K08844
[Journal Article] Xanthinuria Type 1 with a Novel Mutation in Xanthine Dehydrogenase and a Normal Endothelial Function2022
- Author(s)
  Satoshi Miyazaki, hisatome I, et al
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 9 Pages: 1383-1386
- DOI
  10.2169/internalmedicine.7897-21
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-05-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08074, KAKENHI-PROJECT-20K17168, KAKENHI-PROJECT-21K11581, KAKENHI-PROJECT-17K11191
[Journal Article] Thrombin induces a temporal biphasic vascular response through the differential phosphorylation of endothelial nitric oxide synthase via protease-activated receptor-1 and protein kinase C2022
- Author(s)
  Akihiro Okamura, Hisatome I, et al
- Journal Title
  
  Journal of pharmacological sciences
  
  Volume: 48 Issue: 4 Pages: 351-357
- DOI
  10.1016/j.jphs.2022.02.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08074, KAKENHI-PROJECT-21K11675
[Journal Article] Kv1.5 channel mediates monosodium urate-induced activation of NLRP3 inflammasome in macrophages and arrhythmogenic effects of urate on cardiomyocytes2022
- Author(s)
  Peili Li, Yasutaka Kurata, Fikri Taufiq, et al
- Journal Title
  
  Molecular Biology Reports
  
  Volume: online ahead of print Issue: 7 Pages: 0-0
- DOI
  10.1007/s11033-022-07378-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08074, KAKENHI-PROJECT-20K17168, KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-22K06979
[Journal Article] Effect of Subcutaneous Adrenaline/Saline/Lidocaine Injection on Split-Thickness Skin Graft Donor Site Wound Healing2021
- Author(s)
  Fukuoka Kohei、Yagi Shunjiro、Suyama Yoshiko、Kaida Wataru、Morita Maki、Hisatome Ichiro
- Journal Title
  
  Yonago Acta Medica
  
  Volume: 64 Issue: 1 Pages: 107-112
- DOI
  10.33160/yam.2021.02.014
- NAID
  130007989777
- ISSN
  0513-5710, 1346-8049
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09865
[Journal Article] Angiogenic effects of high molecular weight fucoidan in a mouse ischemic limb model2021
- Author(s)
  Maki Morita, Shinobu Sugihara, Yumiko Inoue, Yoshiko Suyama, Shunjiro Yagi, Ichiro Hisatome et al
- Journal Title
  
  Vascular Failure
  
  Volume: accepted
- NAID
  130008086112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11539
[Journal Article] Angiogenic effects of high molecular weight fucoidan in a mouse ischemic limb model2021
- Author(s)
  Morita Maki、Sugihara Shinobu、Inoue Yumiko、Suyama Yoshiko、Notsu Tomomi、Yamamoto Yasutaka、Sakaguchi Hiromi、Fukuoka Kohei、Endo Yusuke、Koga Atsuro、Kawamoto Hitoshi、Funakoshi Minoru、Miki Yasunari、Yagi Shunjiro、Ninomiya Haruaki、Hisatome Ichiro
- Journal Title
  
  Vascular Failure
  
  Volume: 4 Issue: 2 Pages: 61-67
- DOI
  10.30548/vascfail.4.2_61
- NAID
  130008086112
- ISSN
  2432-4477
- Year and Date
  2021-08-31
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09865
[Journal Article] Uric Acid as a Risk Factor for Chronic Kidney Disease and Cardiovascular Disease　― Japanese Guideline on the Management of Asymptomatic Hyperuricemia ―2021
- Author(s)
  Hisatome Ichiro、Li Peili、Miake Junichiro、Taufiq Fikri、Mahati Endang、Maharani Nani、Utami Sulistiyati Bayu、Kuwabara Masanari、Bahrudin Udin、Ninomiya Haruaki
- Journal Title
  
  Circ J
  
  Volume: 85 Issue: 2 Pages: 130-138
- DOI
  10.1253/circj.CJ-20-0406
- NAID
  130007975319
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2021-01-25
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20662, KAKENHI-PROJECT-18K08074, KAKENHI-PROJECT-20K17168
[Journal Article] Evidence for Urate Uptake Through Monocarboxylate Transporter 9 Expressed in Mammalian Cells and Its Enhancement by Heat Shock2020
- Author(s)
  Otani Naoyuki、Kurata Yasutaka、Maharani Nani、Kuwabara Masanari、Ikeda Nobuhito、Notsu Tomomi、Li Peili、Miake Junichiro、Yoshida Akio、Sakaguchi Hiromi、Higaki Katsumi、Nakasone Naoe、Tsuneto Motokazu、Shirayoshi Yasuaki、Ouchi Motoshi、Ninomiya Haruaki、Yamamoto Kazuhiro、Anzai Naohiko、Hisatome Ichiro
- Journal Title
  
  Circulation Reports
  
  Volume: 2 Issue: 8 Pages: 425-432
- DOI
  10.1253/circrep.cr-20-0016
- NAID
  130007885744
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-20K20662, KAKENHI-PROJECT-18K08200, KAKENHI-PROJECT-18K08074
[Journal Article] Multiple Dynamical Mechanisms of Phase-2 Early Afterdepolarizations in a Human Ventricular Myocyte Model: Involvement of Spontaneous SR Ca (2+) Release.2020
- Author(s)
  Kurata Y, Tsumoto K, Hayashi K, Hisatome I, Kuda Y, Tanida M.
- Journal Title
  
  Front Physiol.
  
  Volume: 10 Pages: 1545-1545
- DOI
  10.3389/fphys.2019.01545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08100, KAKENHI-PROJECT-19K07290, KAKENHI-PROJECT-17K09580, KAKENHI-PROJECT-20H04133
[Journal Article] Pretreatment with cilnidipine attenuates hypoxia/reoxygenation injury in HL-1 cardiomyocytes through enhanced NO production and action potential shortening2020
- Author(s)
  Minato Hiroyuki、Hisatome Ichiro、Kurata Yasutaka、Notsu Tomomi、Nakasone Naoe、Ninomiya Haruaki、Hamada Toshihiro、Tomomori Takuya、Okamura Akihiro、Miake Junichiro、Tsuneto Motokazu、Shirayoshi Yasuaki、Endo Ryo、Otsuki Akihiro、Okada Futoshi、Inagaki Yoshimi
- Journal Title
  
  Hypertension Research
  
  Volume: 43 Issue: 5 Pages: 380-388
- DOI
  10.1038/s41440-019-0391-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-17K08761, KAKENHI-PROJECT-20K20662
[Journal Article] Hemodynamic Analysis of a Microanastomosis Using Computational Fluid Dynamics2020
- Author(s)
  Yagi Shunjiro、Sasaki Takafumi、Fukuhara Takahiro、Fujii Kaori、Morita Maki、Suyama Yoshiko、Fukuoka Kohei、Nishino Teruyasu、Hisatome Ichiro
- Journal Title
  
  Yonago Acta Medica
  
  Volume: 63 Issue: 4 Pages: 308-312
- DOI
  10.33160/yam.2020.11.013
- NAID
  130007942214
- ISSN
  0513-5710, 1346-8049
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11539
[Journal Article] Novel dual-reporter transgenic rodents enable cell tracking in animal models of stem cell transplantation2019
- Author(s)
  Morikawa K, Nakamura K, Suyama Y, Yamamoto K, Fukuoka K, Yagi S, Shirayoshi Y, Ohbayashi T, Hisatome I.
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: 18 Pages: 100645-100645
- DOI
  10.1016/j.bbrep.2019.100645
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08539, KAKENHI-PROJECT-17K11539
[Journal Article] Hyperuricemia as a Risk Factor for Atrial Fibrillation Due to Soluble and Crystalized Uric Acid2019
- Author(s)
  Fikri Taufiq, Peili Li*; Junichiro Miake, Ichiro Hisatome,
- Journal Title
  
  Circulation Reports
  
  Volume: 1 Issue: 11 Pages: 469-473
- DOI
  10.1253/circrep.CR-19-0088
- NAID
  130007742752
- ISSN
  2434-0790
- Year and Date
  2019-11-08
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08074
[Journal Article] Inhibitory effects of class I antiarrhythmic agents on Na+ and Ca2+ currents of human iPS cell-derived cardiomyocytes.2019
- Author(s)
  Yonemizu S, Masuda K, Kurata Y, Notsu T, Higashi Y, Fukumura K, Li P, Ninomiya H, Miake J, Tsuneto M, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Regen Ther.
  
  Volume: 10 Pages: 104-111
- DOI
  10.1016/j.reth.2018.12.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08539, KAKENHI-PROJECT-17K09580, KAKENHI-PROJECT-18K08074
[Journal Article] Novel dual-reporter transgenic rodents enable cell tracking in animal models of stem cell transplantation2019
- Author(s)
  Kumi Morikawa, Kazuomi Nakamura, Yoshiko Suyama, Kenshiro Yamamoto, Kohei Fukuoka, Shunjiro Yagi, Yasuaki Shirayoshi, Tetsuya Ohbayashi, Ichiro Hisatome
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11539
[Journal Article] フコイダン前投与により誘導される虚血肢の血管新生作用に関する研究2018
- Author(s)
  野津智美, 櫻木哲詩, 陶山淑子, 八木俊路朗, 久留一郎
- Journal Title
  
  米子医学雑誌
  
  Volume: 69 Pages: 16-24
- NAID
  120006862011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11367
[Journal Article] Restoration of mutant hERG stability by inhibition of HDAC62018
- Author(s)
  Li Peili、Kurata Yasutaka、Endang Mahati、Ninomiya Haruaki、Higaki Katsumi、Taufiq Fikri、Morikawa Kumi、Shirayoshi Yasuaki、Horie Minoru、Hisatome Ichiro
- Journal Title
  
  J mol Cell cardiol
  
  Volume: 115 Pages: 158-169
- DOI
  10.1016/j.yjmcc.2018.01.009
- NAID
  120007170666
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08539, KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-15K08277, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-18K08074
[Journal Article] フコイダン前投与により誘導される虚血肢の血管新生作用に関する研究2018
- Author(s)
  野津　智美、櫻木　哲詩、陶山　淑子、八木　俊路朗、久留　一郎
- Journal Title
  
  米子医学雑誌
  
  Volume: 69 Pages: 16-24
- NAID
  120006862011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11539
[Journal Article] Pretreatment with an angiotensin II receptor blocker abolished ameliorating actions of adipose-derived stem cell sheets on cardiac dysfunction and remodeling after myocardial infarction2018
- Author(s)
  Yamamoto Kenshiro、Kurata Yasutaka、Inoue Yumiko、Adachi Maya、Tsuneto Motokazu、Miake Junichiro、Ogino Kazuhide、Ninomiya Haruaki、Yoshida Akio、Shirayoshi Yasuaki、Suyama Yoshiko、Yagi Shunjiro、Nishimura Motonobu、Yamamoto Kazuhiro、Hisatome Ichiro
- Journal Title
  
  Regenerative Therapy
  
  Volume: 9 Pages: 79-88
- DOI
  10.1016/j.reth.2018.08.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09436, KAKENHI-PROJECT-17K09580, KAKENHI-PROJECT-17K11539, KAKENHI-PROJECT-16K11367
[Journal Article] Isolation and characterization of ventricular-like cells derived from NKX2-5 eGFP/w and MLC2v mCherry/w double knock-in human pluripotent stem cells2018
- Author(s)
  Yamauchi Kaori、Li Junjun、Morikawa Kumi、Liu Li、Shirayoshi Yasuaki、Nakatsuji Norio、Elliott David A.、Hisatome Ichiro、Suemori Hirofumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 495 Issue: 1 Pages: 1278-1284
- DOI
  10.1016/j.bbrc.2017.11.133
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08539, KAKENHI-PROJECT-17K09580
[Journal Article] Cited4 is related to cardiogenic induction and maintenance of proliferation capacity of embryonic stem cell-derived cardiomyocytes during in vitro cardiogenesis2017
- Author(s)
  Miake Junichiro、Notsu Tomomi、Higaki Katsumi、Hidaka Kyoko、Morisaki Takayuki、Yamamoto Kazuhiro、Hisatome Ichiro
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 8 Pages: e0183225-e0183225
- DOI
  10.1371/journal.pone.0183225
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09486, KAKENHI-PROJECT-17K09580
[Journal Article] Molecular mechanisms underlying the pilsicainide-induced stabilization of hERG proteins in transfected mammalian cells2017
- Author(s)
  Onohara, Takeshi; Hisatome, Ichiro; Kurata, Yasutaka; Li, Peili; Notsu, Tomomi; Morikawa, Kumi; Otani, Naoyuki; Yoshida, Akio; Iitsuka, Kazuhiko; Kato, Masaru; Miake, Junichiro; Ninomiya, Haruaki; Higaki, Katsumi; Shirayoshi, Yasuaki; Nishihara, Takashi; Itoh, Toshiyuki; Nakamura, Yoshinobu; Nishimura, Motonobu
- Journal Title
  
  J. Arrhythmia,
  
  Volume: 32 Issue: 3 Pages: 226-233
- DOI
  10.1016/j.joa.2016.09.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26241030, KAKENHI-PROJECT-26501003, KAKENHI-PROJECT-15K21170, KAKENHI-PROJECT-17K08539, KAKENHI-PROJECT-15K08277
[Journal Article] 生物学的ペースメーカの展望2016
- Author(s)
  森川久未, 白吉安昭, 久留一郎.
- Journal Title
  
  心電図
  
  Volume: 34(4) Pages: 264-268
- NAID
  130005139479
- Data Source
  KAKENHI-PROJECT-15K21170
[Journal Article] Effects of Uric Acid on the NO Production of HUVECs and its Restoration by Urate Lowering Agents.2016
- Author(s)
  Mishima M, Anzai N, et al.
- Journal Title
  
  Drug Res
  
  Volume: 66 Issue: 05 Pages: 270-274
- DOI
  10.1055/s-0035-1569405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670600, KAKENHI-PROJECT-25461057, KAKENHI-PROJECT-26461258
[Journal Article] Electrophysiological properties of iPS cell-derived cardiomyocytes from a patient with long QT syndrome type 1 harboring the novel mutation M437V of KCNQ12016
- Author(s)
  Sogo T, Morikawa K, Kurata Y, Li P, Ichinose T, Yuasa S, Nozaki D, Miake J, Ninomiya H, Shimizu W, Fukuda K, Yamamoto K, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Regenerative Therapy
  
  Volume: 4 Pages: 9-17
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K21170
[Journal Article] 脂肪注入移植を用いた乳房再建術】自己皮下脂肪組織由来幹細胞移植による乳房再建2016
- Author(s)
  陶山淑子、福岡晃平、森川久未、久留一郎、八木俊路朗
- Journal Title
  
  形成外科
  
  Volume: 59 Pages: 486-495
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K11367
[Journal Article] Effect of Antihypertensive Drugs on Uric Acid Metabolism in Patients with Hypertension: Cross-Sectional Cohort Study.2016
- Author(s)
  Ueno S, Hamada T, Taniguchi S, Ohtani N, Miyazaki S, Mizuta E, Ohtahara A, Ogino K, Yoshida A, Kuwabara M, Yoshida K, Ninomiya H, Kotake H, Taufiq F, Yamamoto K, Hisatome I
- Journal Title
  
  Drug Res (Stuttg)
  
  Volume: 66 Pages: 628-632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461057
[Journal Article] <b>Adipose stem cell sheets improved cardiac function in the rat myocardial infarction, but did not alter cardiac contractile responses to β-adrenergic stim</b><b>ulation </b>2015
- Author(s)
  Otsuki Y, Nakamura Y, Harada S, Yamamoto Y, Ogino K, Morikawa K, Ninomiya H, Miyagawa S, Sawa Y, Hisatome I, Nishimura M.
- Journal Title
  
  Biomed. Res.
  
  Volume: 36 Issue: 1 Pages: 11-19
- DOI
  10.2220/biomedres.36.11
- NAID
  130004903877
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25893134, KAKENHI-PROJECT-25461057
[Journal Article] Stabilization of Kv1.5 channel protein by the inotropic agent olprinone.2015
- Author(s)
  Endo R, Kurata Y, Notsu T, Li P, Morikawa K, Kondo T, Ogura K, Miake J, Yoshida A, Shirayoshi Y, Ninomiya H, Higaki K, Kuwabara M, Yamamoto K, Inagaki Y, Hisatome I.
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 765 Pages: 488-494
- DOI
  10.1016/j.ejphar.2015.09.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26501003, KAKENHI-PROJECT-15K21170, KAKENHI-PROJECT-25461109
[Journal Article] Molecular Mechanisms Underlying Urate-Induced Enhancement of Kv1.5 Channel Expression in HL-1 Atrial Myocytes2015
- Author(s)
  Maharani N, Ting YK, Cheng J, Hasegawa A, Kurata Y, Li P, Nakayama Y, Ninomiya H, Ikeda N, Morikawa K, Yamamoto K, Makita N, Yamashita T, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Circ J
  
  Volume: 79 Issue: 12 Pages: 2659-2668
- DOI
  10.1253/circj.CJ-15-0416
- NAID
  130005110934
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26501003, KAKENHI-PROJECT-15K15311, KAKENHI-PROJECT-15K21170, KAKENHI-PROJECT-15H04823, KAKENHI-PROJECT-25461109, KAKENHI-PROJECT-24390199
[Journal Article] Depletion of Uric Acid Due to SLC22A12 (URAT1) Loss-of-Function Mutation Causes Endothelial Dysfunction in Hypouricemia2015
- Author(s)
  Sugihara S, Hisatome I, Kuwabara M, Niwa K, Maharani N, Kato M, Ogino K, Hamada T, Ninomiya H, Higashi Y, Ichida K, Yamamoto K
- Journal Title
  
  Circ J
  
  Volume: 79 Issue: 5 Pages: 1125-1132
- DOI
  10.1253/circj.CJ-14-1267
- NAID
  130005066259
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461057, KAKENHI-PROJECT-25461058, KAKENHI-PROJECT-25670762
[Journal Article] Effects of azelnidipine on uric acid metabolism in patients with essential hypertension.2014
- Author(s)
  Igawa O, Ogino K, Kato M, Yoshida A, Ninomiya H, Cheng J, Moriwaki Y, Yamamoto K, Hisatome I.
- Journal Title
  
  Clin Exp Hypertens.
  
  Volume: 16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461387
[Journal Article] Spironolactone, not furosemide, improved insulin resistance in patients with chronic heart failure2014
- Author(s)
  Ogino K, Kinugasa Y, Kato M, Yamamoto K, Hisatome I, Anker SD, Doehner W
- Journal Title
  
  Int J Cardiol
  
  Volume: 171 Issue: 3 Pages: 398-403
- DOI
  10.1016/j.ijcard.2013.12.039
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461057
[Journal Article] Instability of KCNE1-D85N that Causes Long QT Syndrome: Stabilization by Verapamil2014
- Author(s)
  Sakata S, Kurata Y, Li P, Notsu T, Morikawa K, Miake J, Higaki K, Yamamoto Y, Yoshida A, Shirayoshi Y, Yamamoto K, Horie M, Ninomiya H, Kanzaki S, Hisatome I.
- Journal Title
  
  Pacing Clinical Electrophysiology
  
  Volume: Epub ahead of print Issue: 7 Pages: 1-11
- DOI
  10.1111/pace.12360
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591512, KAKENHI-PROJECT-25461109, KAKENHI-PROJECT-25461387, KAKENHI-PROJECT-25670110, KAKENHI-PROJECT-25893134, KAKENHI-PROJECT-26501003
[Journal Article] Transplantation of freshly isolated adipose tissue-derived regenerative cells enhances angiogenesis in a murine model of hind limb ischemia.2013
- Author(s)
  Harada Y, Yamamoto Y, Tsujimoto S, Matsugami H, Yoshida A, Hisatome I
- Journal Title
  
  Biomed Res
  
  Volume: 34 Pages: 23-29
- NAID
  130004470831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591994
[Journal Article] A vasodilating β1 blocker celiprolol inhibits muscular release of uric acid precursor in patients with essential hypertension.2013
- Author(s)
  Mizuta E, Utami SB, Ohtahara A, Endo S, Mishima M, Hasegawa A, Yamada K, Kato M, Yamamoto K, Ogino K, Ninomiya H, Miyazaki S, Hamada T, Taniguchi SI, Cheng J, Hisatome I.
- Journal Title
  
  Horm Metab Res.
  
  Volume: 45(1) Pages: 69-73
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Transplantation of freshly isolated adipose tissue-derived regenerative cells enhances angiogenesis in a murine model of hind limb ischemia.2013
- Author(s)
  Harada Y, Yamamoto Y, Tsujimoto S, Matsugami H, Yoshida A, Hisatome I.
- Journal Title
  
  Biomed Res.
  
  Volume: 34 Pages: 23-29
- NAID
  130004470831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461387
[Journal Article] Transplantation of freshly isolated adipose tissue-derived regenerative cells enhances angiogenesis in a murine model of hind limb ischemia2013
- Author(s)
  Harada Y, Yamamoto Y, Tsujimoto S,Matsugami H, Yoshida A, Hisatome I.
- Journal Title
  
  Biomed Res
  
  Volume: 34(1) Pages: 23-9
- NAID
  130004470831
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Heterochromatin protein 1γ overexpression in P19 embryonal carcinoma cells elicits spontaneous differentiation into the three germ layers2013
- Author(s)
  Morikawa K, Ikeda N, Hisatome I, Shirayoshi Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 431(2) Pages: 225-31
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] AMP deaminase 3 plays a critical role in remote reperfusion lung injury.2013
- Author(s)
  Li P, Ogino K, Hoshikawa Y, Morisaki H, Toyama K, Morisaki T, Morikawa K, Ninomiya H, Yoshida A, Hashimoto K, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 26 Pages: 131-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461387
[Journal Article] Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins2013
- Author(s)
  Iwai C, P Li,
- Journal Title
  
  Cardiovasc Res
  
  Volume: ３ Issue: 3 Pages: 520-528
- DOI
  10.1093/cvr/cvt200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461109, KAKENHI-PROJECT-25461387, KAKENHI-PROJECT-25670110, KAKENHI-PROJECT-25893134
[Journal Article] Heterochromatin protein 1γ overexpression in P19 embryonal carcinoma cells elicits spontaneous differentiation into the three germ layers.2013
- Author(s)
  Morikawa K, Ikeda N, Hisatome I, Shirayoshi Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 431(2) Issue: 2 Pages: 225-31
- DOI
  10.1016/j.bbrc.2012.12.128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J00001, KAKENHI-PROJECT-23659112, KAKENHI-PROJECT-25670110
[Journal Article] Simultaneous Treatment with Azelnidipine and Olmesartan Inhibits Apoptosis of Hl-1 Cardiac Myocytes Expressing E334k cMyBPC2013
- Author(s)
  Bahrudin U, Ikeda N, Utami SB, Maharani N, Morikawa K, Li P
- Journal Title
  
  Drug Res (Stuttg).
  
  Volume: １０ Issue: 10 Pages: 515-520
- DOI
  10.1055/s-0033-1347188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461109, KAKENHI-PROJECT-25670110, KAKENHI-PROJECT-25893134
[Journal Article] Effect of hyperpolarization-activated current If on robustness of sinoatrial node pacemaking: theoretical study on influence of intracellular Na+ concentration2012
- Author(s)
  Kurata Y
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 304 Issue: 10 Pages: 61-7
- DOI
  10.1152/ajpheart.00777.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590806, KAKENHI-PROJECT-23590266, KAKENHI-PROJECT-25670110
[Journal Article] Effects of cilnidipine on serum uric acid level and urinary nitrogen monoxide excretion in patients with hypertension.2012
- Author(s)
  Hamada T, Yamada K, Mizuta E, Watanabe A, Osaki T, Ishida K, HasegawaA, Sakata S, Mishima M, Ogino K, Nosaka Y, Miyazaki S, Ohtahara A, Ninomiya H, Kato M, Yoshida A, Taniguchi S, Yamamoto K, Hisatome I.
- Journal Title
  
  Clin Exp Hypertens
  
  Volume: 34(7) Pages: 470-3
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Nohara R. Proinflammatory cytokine activation is linked to apoptotic mediator, soluble Fas level in patients with chronic heart failure2012
- Author(s)
  Kinugawa T, Kato M, Yamamoto K, Hisatome I
- Journal Title
  
  Int Heart J
  
  Volume: 53(3) Pages: 182-6
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Electrophysiological properties of prion-positive cardiac progenitors derived from murine embryonic stem cells.2012
- Author(s)
  Fujii H, Ikeuchi Y, Kurata Y, Ikeda N, Bahrudin U, Li P, Nakayama Y, Endo R, Hasegawa A, Morikawa K, Miake J,Yoshida A, Hidaka K, Morisaki T, Ninomiya H, Shirayoshi Y, Yamamoto K, Hisatome I.
- Journal Title
  
  Circ J.
  
  Volume: 76(12) Pages: 2875-83
- NAID
  10031126061
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Roles of sarcoplasmic reticulum Ca2+ cycling and Na+/Ca2+ exchanger in sinoatrial node pacemaking: insights from bifurcation analysis of mathematical models2012
- Author(s)
  Kur a t a Y, Hisatome I, Shibamoto T.
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 302(11)
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Udin Bahrudin Carbohydrate diet links to higher risk of significant coronary artery disease in young Indonesian patients Cardiometabolic Investigation study2012
- Author(s)
  Sugiri, Sefri Noventi, Ichiro Hisatome
- Journal Title
  
  Biomedical Research
  
  Volume: 23(2) Pages: 159-165
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Stabilization of Kv1.5 channel protein by bepridil through its action as a chemical chaperone2012
- Author(s)
  Suzuki S, Kurata Y, Li P, Notsu T, Hasegawa A, Ikeda N, Kato M, Miake J, Sakata S, Shiota G, Yoshida A, Ninomiya H, Higaki K, Yamamoto K, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 696(1-3) Pages: 28-34
- NAID
  10027704706
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Reactive oxygen species and NADPH oxidase 4 induced by transforming growth factor β1 are the therapeutic targets of polyenylphosphatidylcholine in the suppression of human hepatic stellate cell activation2011
- Author(s)
  Ikeda R, Ishii K, Hoshikawa Y, Azumi J, Arakaki Y, Yasui T, Matsuura S, Matsumi Y, Kono Y, Mizuta Y, Kurimasa A, Hisatome I, Friedman SL, Kawasaki H, Shiota G.
- Journal Title
  
  Inflamm Res
  
  Volume: 60(6) Pages: 597-604
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Impairment of ubiquitin-proteasome system by E334K cMyBPC modifies channel proteins, leading to electrophysiological dysfunction2011
- Author(s)
  Bahrudin U, Morikawa K, Takeuchi A, Kurata Y, Miake J, Mizuta E, Adachi K, HigakiK, Yamamoto Y, Shirayoshi Y, Yoshida A, Kato M, Yamamoto K, Nanba E, Morisaki H, Morisaki T, Matsuoka S, Ninomiya H, Hisatome I.
- Journal Title
  
  J Mol Biol
  
  Volume: 413(4) Pages: 857-78
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Transcriptional activation of SAP97 by HSF-1 stabilizes Kv1.5 in HL-1 cells2011
- Author(s)
  YK Ting, K Morikawa, Y Kurata, PL Li, U Bahrudin, E Mizuta, M Kato,J Miake, Y Yamamoto, A Yoshida, M Murata, T Inoue, A Nakai, G Shiota, K Higaki, E Nanba, H Ninomiya, Y Shirayoshi, I Hisatome.
- Journal Title
  
  Br J Pharmacol
  
  Volume: 162(8) Pages: 1832-1842
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Enhancing effects of salicylate on quinidine-induced block of human wild type and LQT3 related mutant cardiac Na+ channels2011
- Author(s)
  Urashima T, Kurata Y, Miake J, Kato M, Ogura K, Yano A, Adachi M, Tanaka Y, Yamada K, Hamada T, Mizuta E, Kuwabara M, Kato M, Yamamoto Y, Ogino K, Yoshida A, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Biomed Res
  
  Volume: 32(5) Pages: 303-12
- NAID
  130004724056
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Novel effects of extracts from poisonous mushrooms on expression and function of the human ether-a-go-go-related gene channel.2011
- Author(s)
  Li P, Tanaka S, Ichiyanagi T, Ninomiya H, Ting Y, Utami SB, Aimi T, Shirayoshi Y, Miake J, Hisatome I.
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 34(9) Pages: 1474-80
- NAID
  130001872443
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Reciprocal Control of hERG Stability by Hsp70 and Hsc70 with Implication for Restoration of LQT2 Mutant Stability2011
- Author(s)
  Peili Li, Haruaki Ninomiya, Yasutaka Kurata, Masaru Kato, Junichiro Miake, Yasutaka Yamamoto, Osamu Igawa, Akira Nakai, Katsumi Higaki, Futoshi Toyoda, Jie Wu, Minoru Horie, Hiroshi Matsuura, Akio Yoshida, Yasuaki Shirayoshi, Masayasu Hiraoka, Ichiro Hisatome.
- Journal Title
  
  Circ Res.
  
  Volume: 108(4) Pages: 458-68
- NAID
  130002130408
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Chemical chaperone therapy: chaperone effect on mutant enzyme and cellular pathophysiology in β-galactosidase deficiency2011
- Author(s)
  Higaki K, Li L, Bahrudin U, Okuzawa S, Takamura A, Yamamoto K, Adachi K, Paraguison RC, Takai T, Ikehata H, Tominaga L, Hisatome I, Iida M, Ogawa S, Matsuda J, Ninomiya H, Sakakibara Y, Ohno K, Suzuki Y, Nanba E.
- Journal Title
  
  Hum Mutat
  
  Volume: 32(7) Pages: 843-852
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] c-Jun N-terminal kinase activation by oxidative stress suppresses retinoid signaling through proteasomal degradation of retinoic acid receptor α protein in hepatic cells.2011
- Author(s)
  Hoshikawa Y, Kanki K, Ashla AA, Arakaki Y, Azumi J, Yasui T, Tezuka Y, Matsumi Y, Tsuchiya H, Kurimasa A, Hisatome I, Hirano T, Fujimoto J, Kagechika H, Shomori K, Ito H, Shiota G.
- Journal Title
  
  Cancer Sci.
  
  Volume: 120(5) Pages: 934-41
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Cytosolic Phospholipase A2{alpha} Contributes to Blood Pressure Increases and Endothelial Dysfunction Under Chronic NO Inhibition2011
- Author(s)
  Tanaka K, Yamamoto Y, Ogino K, Tsujimoto S, Saito M, Uozumi N, Shimizu T, Hisatome I.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(5) Pages: 1133-8
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Disrupted plasma membrane localization of equilibrative nucleoside transporter 2 in the chemoresistance of human pancreatic cells to gemcitabine (dFdCyd)2011
- Author(s)
  16. Nishio R, Tsuchiya H, Yasui T, Matsuura S, Kanki K, Kurimasa A,Hisatome I, Shiota G.
- Journal Title
  
  Cancer Sci
  
  Volume: 102(3) Pages: 622-9
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Reciprocal Control of hERG Stability by Hsp70 and Hsc70 with Implication for Restoration of LQT2 Mutant Stability2010
- Author(s)
  Peili Li, Haruaki Ninomiya, Yasutaka Kurata, Masaru Kato, Junichiro Miake, Yasutaka Yamamoto, Osamu Igawa, Akira Nakai, Katsumi Higaki, Futoshi Toyoda, Jie Wu, Minoru Horie, Hiroshi Matsuura, Akio Yoshida, Yasuaki Shirayoshi, Masayasu Hiraoka, Ichiro Hisatome
- Journal Title
  
  Circ Res (in press)
- NAID
  130002130408
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Transcriptional activation of SAP97 by HSF-1 stabilizes Kv1.5 in HL-1 cells2010
- Author(s)
  YK Ting, K Morikawa, Y Kurata, PL Li, U Bahrudin, E Mizuta, M Kato, J Miake, Y Yamamoto, A Yoshida, M Murata, T Inoue, A Nakai, G Shiota, K Higaki, E Nanba, H Ninomiya, Y Shirayoshi, I Hisatome
- Journal Title
  
  British J Pharmacol (in press)
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Roles of hyperpolarization-activated current If in sinoatrial node pacemaking : insights from bifurcation analysis of mathematical models Am J Physiol2010
- Author(s)
  Kurata Y, Matsuda H, Hisatome I, Shibamoto T
- Journal Title
  
  Heart Circ Physiol 298
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Addition of losartan to angiotensin- converting enzyme inhibitors improves insulin resistance in patients with chronic heart failure treated without β-blockers.2010
- Author(s)
  Ogino K, Kato M, Furuse Y, Kinugasa Y, Kaetsu Y, Mizuta E, Sugihara S, Ishida K, Yanagihara K, Hisatome I, Shigemasa C.
- Journal Title
  
  Circ J. 74
  
  Pages: 2346-2352
- NAID
  10026972758
- Data Source
  KAKENHI-PROJECT-20590826
[Journal Article] Identification, isolation and characterization of HCN4-positive pacemaking cells derived from murine embryonic stem cells during cardiac differentiation2010
- Author(s)
  Morikawa K, Bahrudin U, Miake J, Igawa O, Kurata Y, Nakayama Y, Shirayoshi Y, Hisatome I
- Journal Title
  
  Pacing Clin Electrophysiol 33
  
  Pages: 290-303
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Different distribution of Cav3.2 and Cav3.1 transcripts encoding T-type Ca^<2+> channels in the embryonic heart of mice2010
- Author(s)
  Mizuta E, Shirai M, Arakawa K, Hidaka K, Miake J, Ninomiya H, Kato M, Shigemasa C, Shirayoshi Y, Hisatome I, Morisaki T
- Journal Title
  
  Biomed Res 31
  
  Pages: 301-305
- NAID
  130004903809
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Uric acid-lowering treatment with benzbromarone in patients with heart failure : a doubleblind placebo-controlled crossover preliminary study.2010
- Author(s)
  Ogino K, Kato M, Furuse Y, Kinugasa Y, Ishida K, Osaki S, Kinugawa T, Igawa O, Hisatome I, Shigemasa C, Anker SD, Doehner W.
- Journal Title
  
  Circ Heart Fail. Jan;3:
  
  Pages: 73-81
- Data Source
  KAKENHI-PROJECT-20590826
[Journal Article] Extrinsic factors derived from mouse embryonal carcinoma cell lines maintain pluripotency of mouse embryonic stem cells through a novel signal pathway.2009
- Author(s)
  Kawazoe S, Ikeda N, Miki K, Shibuya M, Morikawa K, Nakano S, Oshimura M, Hisatome I, Shirayoshi Y.
- Journal Title
  
  Dev Growth Differ. 51(2)
  
  Pages: 81-93
- NAID
  10025373749
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Stabilizing effects of eicosapentaenoic acid on Kv1.5 channel protein expressed in mammalian cells.2009
- Author(s)
  Koshida S, Kurata Y, Notsu T, Hirota Y, Kuang TY, Li P, Bahrudin U, Harada S, Miake J, Yamamoto Y, Hoshikawa Y, Igawa O, Higaki K, Soma M, Yoshida A, Ninomiya H, Shiota G, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Eur J Pharmacol. 604(1-3)
  
  Pages: 93-102
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Fenofibrate enhances neovascularization in a murine ischemic hindlimb model.2009
- Author(s)
  Katayama A, Yamamoto Y, Tanaka K, Matsubara K, Sugitani M, Fujihara S, Harada S, Kaetsu Y, Yoshida A, Hisatome I.
- Journal Title
  
  J Cardiovasc Pharmacol. 54(5)
  
  Pages: 399-404
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Synergistic effects of autologous cell and hepatocyte growth factor gene therapy for neovascularization in a murine model of hindlimb ischemia.2009
- Author(s)
  Yamamoto Y, Matsuura T, Narazaki G, Sugitani M, Tanaka K, Maeda A, Shiota G, Sato K, Yoshida A, Hisatome I.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 297(4)
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Pendrin is a novel autoantigen recognized by patients with autoimmune thyroid diseases.2009
- Author(s)
  Yoshida A, Hisatome I, Taniguchi S, Shirayoshi Y, Yamamoto Y, Miake J, Ohkura T, Akama T, Igawa O, Shigemasa C, Kamijo K, Ikuyama S, Caturegli P, Suzuki K.
- Journal Title
  
  J Clin Endocrinol Metab. 94(2)
  
  Pages: 442-448
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Changes of HCN gene expression and I(f) currents in Nkx2.5-positive cardiomyocytes derived from murine embryonic stem cells during differentiation.2008
- Author(s)
  Yano S, Miake J, Mizuta E, Manabe K, Bahrudin U, Morikawa K, Arakawa K, Sasaki N, Igawa O, Shigemasa C, Yamamoto Y, Morisaki T, Hidaka K, Kurata Y, Yoshida A, Shiota G, Higaki K, Ninomiya H, Lee JK, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Biomed Res. 29(4)
  
  Pages: 195-203
- NAID
  130004470715
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Functional stabilization of Kv1.5 protein by Hsp70 in mammalian cell lines.2008
- Author(s)
  Hirota Y, Kurata Y, Kato M, Notsu T, Koshida S, Inoue T, Kawata Y, Miake J, Bahrudin U, Li P, Hoshikawa Y, Yamamoto Y, Igawa O, Shirayoshi Y, Nakai A, Ninomiya H, Higaki K, Hiraoka M, Hisatome I.
- Journal Title
  
  Biochem Biophys Res Commun. 372(3)
  
  Pages: 469-474
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Regional difference in dynamical property of sinoatrial node pacemaking : role of Na+ channel current Biophys J.2008
- Author(s)
  Kurata Y, Matsuda H, Hisatome I, Shibamoto T.
- Journal Title
  
  95(2)
  
  Pages: 951-977
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] Long-term reliability of AAI mode pacing in patients with sinus node dysfunction and low Wenckebach block rate.2008
- Author(s)
  Adachi M, Igawa O, Yano A, Miake J, Inoue Y, Ogura K, Kato M, Iitsuka K, Hisatome I.
- Journal Title
  
  Europace. 10(2)
  
  Pages: 134-137
- Data Source
  KAKENHI-PROJECT-20590866
[Journal Article] State-dependent blocking actions of azimilide dihydrochrolide (NE-10064) on human cardiac Na+ channel.2004
- Author(s)
  Miake J, Kurata Y, Iizuka K, Furuichi H, Manabe K, Sasaki N, Yamamoto Y, Hoshikawa Y, Taniguchi S, Yoshida A, Igawa O, Makita N, Shiota G, Nanba E, Ohgi S, Narahashi T, Hisatome I.
- Journal Title
  
  Circ J. 68(7)
  
  Pages: 703-711
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590978
[Journal Article] Detection of the novel autoantibody (anti-UACA antibody) in patients with Graves' disease.2004
- Author(s)
  Ohkura T, Taniguchi S, Yamada K, Nishio N, Okamura T, Yoshida A, Kamijou K, Fukata S, Kuma K, Inoue Y, Hisatome I, Senju S, Nishimura Y, Shigemasa C.
- Journal Title
  
  Biochemical and Biophysical Research Communications 321
  
  Pages: 432-440
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590978
[Journal Article] Mechanism of iodide/chloride exchange by Pendrin.2004
- Author(s)
  Yoshida A, Hisatome I, Taniguchi S, Sasaki N, Yamamoto Y, Miake J, Fukui H, Shimizu H, Okamura T, Okura T, Igawa O, Shigemasa C, Green ED, Kohn LD, Suzuki K
- Journal Title
  
  Endocrinology.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590978
[Journal Article] Abnormally high expression of Proteasome Activator-g(PA28-g) in Thyroid Neoplasm.2003
- Author(s)
  Okamura T, Taniguchi S, Ohkura T, Yoshida A, Shimizu H, Sakai M, Maeta H, Fukui H, Ueta Y, Hisatome I, Shigemasa C.
- Journal Title
  
  J Clin Endocrinol Metab 88(3)
  
  Pages: 1374-1383
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590978
[Journal Article] Acute secondary gastrointestinal amyloidosis in a patient with rheumatoid arthritis.2003
- Author(s)
  Shimoyama M, Ohtahara A, Fukui H, Okamura T, Shimizu H, Miyamoto M, Yamawaki M, Taniguchi S, Ueda Y, Hisatome I, Shigemasa C.
- Journal Title
  
  Am J Med Sci. 326(3)
  
  Pages: 145-147
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590978
[Journal Article] AMP deaminase 3 plays a critical role in remote reperfusion lung injury.
- Author(s)
  Li P, Ogino K, Hoshikawa Y, Morisaki H, Toyama K, Morisaki T, Morikawa K, Ninomiya H, Yoshida A, Hashimoto K, Shirayoshi Y, Hisatome I.
- Journal Title
  
  Biochem Biophys Res Commun.
- Data Source
  KAKENHI-PROJECT-23659112
[Journal Article] Effect of Hyperpolarization-Activated Current If on Robustness of Sinoatrial Node Pacemaking: theoretical study on influence of intracellular Na+ concentration
- Author(s)
  Kurata Y, Biochem Biophys Res Commun. (in press)Hisatome I, Tanida M, Shibamoto T.
- Journal Title
  
  Am J Physiol Heart Circ Physiol
- Data Source
  KAKENHI-PROJECT-23659112
[Patent] 新規刺激伝導系細胞様細胞2018
- Inventor(s)
  白吉安昭、森川久未、久留一郎
- Industrial Property Rights Holder
  白吉安昭、森川久未、久留一郎
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-062705
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K09580
[Patent] 新規ペースメーカ細胞2014
- Inventor(s)
  池田信人、久留一郎
- Industrial Property Rights Holder
  池田信人、久留一郎
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-198466
- Filing Date
  2014-12-25
- Data Source
  KAKENHI-PROJECT-25670110
[Patent] 安全性の高い再生医療技術の確立2013
- Inventor(s)
  久留一郎
- Industrial Property Rights Holder
  鳥取大学
- Filing Date
  2013-01-30
- Data Source
  KAKENHI-PROJECT-23659112
[Patent] 安全性の高い再生医療技術の確立2013
- Inventor(s)
  久留一郎
- Industrial Property Rights Holder
  久留一郎
- Industrial Property Rights Type
  特許
- Filing Date
  2013-01-30
- Data Source
  KAKENHI-PROJECT-23659112
[Patent] 新規ペースメーカ細胞2010
- Inventor(s)
  久留一郎, ら
- Industrial Property Rights Holder
  鳥取大学
- Filing Date
  2010-09-24
- Overseas
- Data Source
  KAKENHI-PROJECT-20590866
[Patent] 新規ペースメーカ2010
- Inventor(s)
  久留一郎、白吉安昭、三明淳一朗
- Industrial Property Rights Holder
  大学法人鳥取大学
- Filing Date
  2010-09-29
- Data Source
  KAKENHI-PROJECT-20590866
[Patent] 新規ペースメーカ2009
- Inventor(s)
  久留一郎、白吉安昭、三明淳一朗
- Industrial Property Rights Holder
  大学法人鳥取大学
- Industrial Property Number
  2009-226760
- Filing Date
  2009-09-30
- Data Source
  KAKENHI-PROJECT-20590866
[Patent] 特許2009
- Inventor(s)
  久留一郎
- Industrial Property Rights Holder
  鳥取大学
- Industrial Property Number
  2009-226760
- Filing Date
  2009-09-30
- Acquisition Date
  2009-12-25
- Data Source
  KAKENHI-PROJECT-20590866
[Patent] 心房リモデリング治療薬2008
- Inventor(s)
  久留一郎
- Industrial Property Rights Holder
  久留一郎
- Industrial Property Number
  2008-148303
- Filing Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-20590866
[Presentation] 尿酸塩結晶がヒト血管内皮細胞へ与える影響の解析2023
- Author(s)
  經遠智一, 勝倉　由夏, 久留一郎
- Organizer
  第５６回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-19K08557
[Presentation] Direct effects of monosodium urate crystal on human endothelial cells in hyperuricemia2022
- Author(s)
  Mototkazu Tsuneto, Yuka Katsukura, Naruomi Yamada, Akika Fukawa, Ichiro Hisatome
- Organizer
  第５１回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K08557
[Presentation] 多血小板血漿(PRP)が脂肪由来幹細胞 (ADSCs)の血管新生作用に及ぼす影響についての検討2022
- Author(s)
  森田真紀，野津智美，陶山淑子，福岡晃平，經遠智一，白吉安昭，八木俊路朗，久留一郎
- Organizer
  第21回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-20K09865
[Presentation] ヒト血管内皮細胞への尿酸塩結晶の影響の検討2022
- Author(s)
  經遠智一, 江橋　由夏, 久留一郎
- Organizer
  第５５回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-19K08557
[Presentation] HCN4/Shox2 遺伝子標識によるヒト iPS 細胞からの心臓洞房結節ペースメーカ細胞の分取システムの構築2021
- Author(s)
  脇水孝之, 經遠智一, 白吉安昭, 久留一郎
- Organizer
  心電学関連春季大会2021
- Data Source
  KAKENHI-PROJECT-19K08557
[Presentation] An investigation of human cardiac pacemaker cells differentiation process using human induced pluripotent stem cells visualizing HCN4/Shox2 gene2021
- Author(s)
  Wakimizu T, Tsuneto M, Shirayoshi Y, Hisatome I
- Organizer
  The18th Stem Cell Research Symposium
- Data Source
  KAKENHI-PROJECT-19K08557
[Presentation] HCN4/Shox2遺伝子標識によるヒトiPS細胞由来心臓ペースメーカ細胞の分取システムの構築と機能解析2021
- Author(s)
  脇水孝之, 經遠智一, 久留一郎, 白吉安昭
- Organizer
  第 44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K08557
[Presentation] HDAC6 regulates electrophysiological properties of HL-1 cells via ERG channel2019
- Author(s)
  Peili Li, Yasutaka Kurata, Fikri Taufiq, Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  第８３回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08074
[Presentation] 非培養皮下脂肪由来再生幹細胞(ADSCs)を用いた乳癌術後乳房変形に対する乳房再建の臨床研究2019
- Author(s)
  陶山　淑子、福岡　晃平、森田　真紀、八木　俊路朗、久留　一郎、原田　雄輔、岩畔　英樹、森川　久未
- Organizer
  第18回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-17K11539
[Presentation] 自己皮下脂肪組識由来幹細胞(ADSC)による乳房再建術の長期経過2019
- Author(s)
  陶山淑子、福岡晃平、森田真紀、八木俊路朗、久留一郎
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16K11367
[Presentation] 非培養皮下脂肪由来再生幹細胞(ADSCs)を用いた乳癌術後乳房変形に対する乳房再建の臨床試験2019
- Author(s)
  陶山淑子、福岡晃平、森田真紀、八木俊路朗、久留一郎
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16K11367
[Presentation] Kv1.5 Channels regulate the NLRP3 Inflammasome activation in macrophages induced by monosodium Urate2019
- Author(s)
  Peili Li, Yasutaka Kurata, Fikri Taufiq , Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  第66回日本不整脈心電学会学術大会
- Data Source
  KAKENHI-PROJECT-18K08074
[Presentation] 自己皮下脂肪組織由来幹細胞(ADSC)による乳房再建術の長期経過2019
- Author(s)
  陶山　淑子、福岡　晃平、森田　真紀、八木　俊路朗、森川　久未、久留　一郎
- Organizer
  第18回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-17K11539
[Presentation] Cited4 is related to cardiogenic induction and maintenance of proliferation capacity of embryonic stem cell-derived cardiomyocytes during in vitro cardiogenesis.2018
- Author(s)
  Miake J, Notsu T, Yamamoto K, Hisatome I.
- Organizer
  第108回日本循環器学会集会
- Data Source
  KAKENHI-PROJECT-17K09580
[Presentation] ヒトiPS細胞由来心筋（iCell CMs）の電気生理学的特性とClass 1群抗不整脈薬によるNa+ならびにCa2+ channel阻害効果2018
- Author(s)
  米水彩香、増田啓一郎、東祐平、福村健太、三明淳一郎、小倉一能、白吉安昭、山本一博、久留一郎
- Organizer
  第１７回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-17K09580
[Presentation] 心臓発生メカニズムの解明を目的とする新規hiPS細胞株の樹立と解析2018
- Author(s)
  東祐平、福村健太、増田啓一郎、米水彩香、宮城香乃望、足立隆、久留一郎、經遠智一、白吉安昭
- Organizer
  第4１回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K09580
[Presentation] ヒトiPS細胞由来心筋（iCell CMs）の電気生理学的特性とClass 1群抗不整脈薬によるNa+ならびにCa2+ channel阻害効果2018
- Author(s)
  増田啓一郎、米水彩香、東祐平、福村健太、三明淳一郎、小倉一能、白吉安昭、山本一博、久留一郎
- Organizer
  第65回日本不整脈心電学会
- Data Source
  KAKENHI-PROJECT-17K09580
[Presentation] 虚血性心不全モデルに対する脂肪幹細胞シートと心不全薬の併用効果の検討2017
- Author(s)
  山本堅士郎、丹野翔伍、足立真彩、森川久未、大月優樹、大谷直由、陶山淑子、八木俊路朗、荻野和秀、三明淳一朗、白吉安昭、山本一博、西村元延、久留一郎
- Organizer
  第16回　日本再生医療学会総会
- Place of Presentation
  仙台、仙台国際センター
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Fluorescent human iPS reporter lines offer useful platforms to study cardiac subtype specification and cell-based therapies of cardiac disease.2017
- Author(s)
  Yasuaki Shirayoshi, Kenta Fukumura, Kumi Morikawa, Ichiro Hisatome
- Organizer
  ISSCR (International Society of Stem Cell Research) 2017 Annual Meeting
- Place of Presentation
  Boston, Boston Convention and Exhibition Center
- Year and Date
  2017-06-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Fluorescent Human iPS/ES Reporter Lines Offer the Opportunity to Track Cardiac Subtype Cells in Cell-based Therapies and Drug Development.2017
- Author(s)
  Yasuaki Shirayoshi, Kumi Morikawa, Kenta Fukumura, Ichiro Hisatome
- Organizer
  第81回　日本循環器学会学術集会
- Place of Presentation
  金沢, 石川県立音楽堂他
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] ヒトiPS細胞に由来する心筋前駆細胞の選別採取とその解析2017
- Author(s)
  東祐平、福村健太、増田啓一郎、米水彩香、久留一郎、白吉安昭
- Organizer
  第40回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K09580
[Presentation] ヒトiPS細胞に由来するHCN4陽性心筋前駆細胞の解析2016
- Author(s)
  福村健太、横井文香、森川久未、野崎大蔵、久留一郎、白吉安昭
- Organizer
  第39回　日本分子生物学会年会
- Place of Presentation
  横浜, パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Stabilization of Kv1.5 Channel Protein by Olprinone as a Chemical Chaperone2016
- Author(s)
  Ryo Endo, Yasutaka Kurata, Peili Li, Kumi Morikawa, Takehito Kondo, Kazuyoshi Ogura, Junichiro Miake, Kazuhiro Yamamoto, Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  The80th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Electrophysiological Properties of iPS Cell-Derived Cardiomyocytes from a Patient with LQT1 Harboring the Novel Mutation M437V of KCNQ12016
- Author(s)
  Yasutaka Kurata, Peili Li, Kumi Morikawa, Junichiro Miake, Kazuhiro Yamamoto, Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  The80th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Generation of Biological Pacemaker Derived from Human Pluripotent Stem Cells2016
- Author(s)
  Yasuaki Shirayoshi, Kumi Morikawa, Junichiro Miake, Ichiro Hisatome
- Organizer
  The80th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-03-18
- Invited
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Losartan/hydrochlorothiazide combination therapy improved left ventricular diastolic dysfunction in patients with hypertension in comparison with a high-dose therapy of losartan2016
- Author(s)
  Ogino K, Kinugasa Y, Kato M, Hisatome I, Yamamoto K
- Organizer
  American Society of Hypertension 2016
- Place of Presentation
  Hilton Hotel, New York, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461057
[Presentation] 選別純化したヒト多能性幹細胞由来分化誘導心筋に関する電気生理学的特性と薬剤応答性の評価2016
- Author(s)
  白吉安昭、森川久未、山内香織、横井文香、福村健太、野崎大蔵、末盛博文、久留一郎
- Organizer
  第43回　日本毒性学会
- Place of Presentation
  名古屋, ウインクあいち
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] HCN4 Positive Cells Derived from Pluripotent Stem Cells Show Automaticity and Pacemaking Ability2015
- Author(s)
  Yasuaki Shirayoshi, Kumi Morikawa, Junichiro Miake, Ichiro Hisatome
- Organizer
  The79th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2015-04-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Stabiliation of Kv1.5 Channel Protein by Olprinone2015
- Author(s)
  Ryo Endo, Yasutaka Kurata, Peili Li, Kumi Moeikawa, Tatehito Kondo, Kazuyoshi Ogura, Junichiro Miake, Kazuhiro Yamamoto, Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  第32回日本心電学会学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Isolation and Characterization of HCN4 positive cells derived from human embryonic stem cells2015
- Author(s)
  Kumi Morikawa, Nozaki Daizou, Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  ISSCR (International Society of Stem Cell Research) 13th Annual Meeting
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] Electrophysiological properties of iPS cell-derived cardiomyocytes from a patient with long QT syndrome type 1 harboring a novel mutation of KCNQ12015
- Author(s)
  Yasutaka Kurata, Peili Li, Kumi Moeikawa, Junichiro Miake Kazuhiro Yamamoto, Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  第32回日本心電学会学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15K21170
[Presentation] ヒト末梢血T細胞由来人工多能性幹(hTiPS)細胞の樹立と心筋分化誘導ならびにその特性解析2013
- Author(s)
  十川達文.三明淳一朗.山本 ―博.白吉安昭.久留一郎
- Organizer
  第103回日本循環器学会中国地方会
- Place of Presentation
  米子市　米子ビッグシップ
- Data Source
  KAKENHI-PROJECT-25670110
[Presentation] QT延長症候群における早期後脱分極発現の力学的機序:ヒト心室筋細胞モデルの分岐構造解析による検証2013
- Author(s)
  倉田康孝.久留一郎.谷田守.芝本利重
- Organizer
  第30回日本心電学会学術集会
- Place of Presentation
  横浜市　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25670110
[Presentation] E3 ligase CHIP interacts with Hsc70 to regulate Kv1.5 expression and repolarization　in HL-1 cells2013
- Author(s)
  Peili Li, Masaru Kato, Junichiro Miake, Kazuhiro Yamamoto, Yasuaki Shirayoshi, Ichiro Hisatome
- Organizer
  第30回日本心電学会学術集会
- Place of Presentation
  横浜市　パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25670110
[Presentation] ACE阻害薬治療中の心不全におけるロサルタン追加投与のインスリン抵抗性に及ぼす影響2011
- Author(s)
  荻野和秀、水田栄之助、杉原志伸、柳原清孝、石田勝則、衣笠良治、古瀬祥之、加藤雅彦、浜田紀宏、重政千秋、山本康孝、久留一郎
- Organizer
  第44回日本痛風核酸代謝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] The effects of losartan on insulin resistance in patients with chronic heart failure treated with ACE inhibitors.2011
- Author(s)
  荻野和秀、水田栄之助、杉原志伸、柳原清孝、石田勝則、衣笠良治、古瀬祥之、加藤雅彦、浜田紀宏、重政千秋、山本康孝、久留一郎
- Organizer
  プリン・ピリミジン代謝国際シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] Matrix metalloproteinase were produced in failing hearts and were decreased with spironolactone in patients with chronic heart failure.2009
- Author(s)
  荻野和秀、加藤雅彦、久留一郎、重政千秋
- Organizer
  ヨーロッパ心不全学会
- Place of Presentation
  ニース
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] Spironolactone, not furosemide, improved insulin resistance in patients with chronic heart failure.2009
- Author(s)
  荻野和秀、加藤雅彦、久留一郎、重政千秋
- Organizer
  日本循環器学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] Matrix metalloproteinases were produced in failing hearts and were decreased with spironolactone in patients with chronic heart failure.2008
- Author(s)
  荻野和秀、加藤雅彦、久留一郎、重政千秋
- Organizer
  アメリカ心不全学会
- Place of Presentation
  トロント
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] Hsp90 Prevents Interaction between CHIP and HERG Proteins to Facilitate Maturation of Wild-type and Mutant HERG Proteins
- Author(s)
  Peili Li, Yasutaka Kurata, Nani Maharani, Yuko Ishido, Juichiro Miake, Yasuaki Shirayoshi, Kazuhiro Yamamoto, Ichiro Hisatome
- Organizer
  第29回日本不整脈学会・第31回日本心電学会学術集会
- Place of Presentation
  東京フォーラム　東京都千代田区
- Year and Date
  2014-07-22 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-25670110
[Presentation] Stabilization of A78T-HERG that Causes Long QT Syndrome Type2 by Heat Shock Protein Family
- Author(s)
  TakehitoKondo, JunichiroMiake, Kazuyoshi Ogura, Masaru Kato, Kazuhiko Iitsuka, Kazuhiro Yamamoto Yasuaki　Shirayoshi, Ichiro Hisatome.
- Organizer
  第29回日本不整脈学会・第31回日本心電学会学術集会
- Place of Presentation
  東京フォーラム　東京都千代田区
- Year and Date
  2014-07-22 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-25670110
[Presentation] Electrical properties of human iPS cell-derived cardiac myocytes from the patient with long QT syndrome harboring a novel mutation of KCNQ1.
- Author(s)
  十川達文、一ノ瀬貴史、森川久未、池田信人、白吉安昭、倉田康孝、三明淳一朗、山本一博、湯浅慎介、福田恵一、久留一郎
- Organizer
  第29回日本不整脈学会・第31回日本心電学会学術集会
- Place of Presentation
  東京フォーラム　東京都千代田区
- Year and Date
  2014-07-22 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-25670110

1. TANIGUCHI Shinichi (30304207)

# of Collaborated Projects: 8 results

# of Collaborated Products: 5 results
2. MIAKE Junichiro (40372677)

# of Collaborated Projects: 7 results

# of Collaborated Products: 21 results
3. SHIRAYOSHI Yasuaki (90249946)

# of Collaborated Projects: 6 results

# of Collaborated Products: 47 results
4. YAMAMOTO Yasutaka (20362882)

# of Collaborated Projects: 5 results

# of Collaborated Products: 21 results
5. OGINO Kazuhide (70294311)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results
6. IGAWA Osamu (80252857)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
7. MORISAKI Takayuki (30174410)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
8. SUYAMA Yoshiko (90448192)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
9. Yagi Shunjiro (00378192)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
10. Morikawa Kumi (90707217)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
11. 福岡晃平 (40548781)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
12. TANAKA Yasunori (60294310)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. NAKAYAMA Bin (50271565)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. KITANO Hiroya (20153108)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. HOSHIKAWA Yoshiko (10181489)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. SUZUKI Koichi (20206478)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. UETA Yoshihiko (80283993)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. SASAKI Norihito (70346336)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. KURATA Yasutaka (00267725)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
20. NINOMIYA Haruaki (80212124)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. LI Peili (40464292)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
22. TSUNETO Motokazu (60730207)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
23. 足立正光 (90343277)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
24. OHTAHARA Akira

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
25. YOSHIDA Akio (90158428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
26. IKEDA Nobuhito (50620316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
27. CHIAKI Shigemasa (50111125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. ITOH Toshiyuki (50193503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
29. TAKENAKA Atsushi (50368669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 加藤克 (40467709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 本田正史 (20362890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 森田真紀 (60838407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. 藤井香綸 (80890326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 梅田竜之介 (30913793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 生田健人 (20913792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 浜田紀宏 (30362883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 尾崎米厚 (00224212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 井上和興 (60739085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. SUGA Masamitsu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. NARASAKI Koji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. YAZAWA Masayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 真鍋一郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. HAYASHI Kenshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 森崎裕子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 安西尚彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 神崎晋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HISATOME Ichiro 久留 一郎

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Deep learning-based identification of sinoatrial node-like pacemaker cells from SHOX2/HCN4 double positive cells differentiated from human iPS cellsPrincipal Investigator

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Development of progenitors of bioogical pacemaker from human iPS cellsPrincipal Investigator

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Stabilization of KvLQT1 by Hsp70 in differentiiated cardiomyocytes derived from LQT1 iPS cellsPrincipal Investigator

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Establishment of human pluripotent stem cell-derived pace-making cells using physiological approach and its application to the regenerative medicinePrincipal Investigator

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HISATOME Ichiro 久留一郎