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Nishio Makoto  西尾 誠人

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NISHIO Makoto  西尾 誠人

NISIO Makoto  西尾 誠人

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Researcher Number 00281593
Other IDs
Affiliation (Current) 2025: 公益財団法人がん研究会, 有明病院 呼吸器内科, 部長
Affiliation (based on the past Project Information) *help 2016 – 2018: 公益財団法人がん研究会, 有明病院 呼吸器内科, 部長
2017: がん研究会がん研有明病院, 呼吸器内科, 部長
2015 – 2016: 公益財団法人がん研究会, 有明病院・呼吸器内科, 部長
2014: 公益財団法人がん研究会, その他部局等, その他
2013: 公益財団法人がん研究会, 有明病院 呼吸器内科, 部長 … More
2012: 公益財団法人がん研究会, 有明病院呼吸器内科, 部長
2010: 財団法人癌研究会, 癌研究所, 研究員
2003 – 2004: 財団法人癌研究会, 癌研究所, 研究員
2001: 財団法人 癌研究会, 癌研究所, 研究員
2001: Cancer Institute, Associate, 癌研究所, 研究員
2000: (財)癌研究会, 癌研究所, 研究員 Less
Review Section/Research Field
Principal Investigator
Medical pharmacy / Tumor diagnosis
Except Principal Investigator
Human pathology / Clinical nursing / Tumor diagnostics / Tumor therapeutics / Human pathology
Keywords
Principal Investigator
lung cancer / epidermal growth factor receptor / gefitinib / 手術材料 / 再発症例 / 免疫染色 / Her family受容体 / EGFR / 化学療法感受性 / 肺がん … More / 肺癌 / 上皮成長因子受容体 / ゲフィチニブ / 免疫組織化学 / 予後 / マイクロアレイ / TTF-1 / 小細胞肺がん … More
Except Principal Investigator
肺癌 / 肺がん / 遺伝子変異 / ALK / 免疫染色 / 遺伝子変化 / 病理組織像 / 多様性 / バイオマーカー / 腫瘍内多様性 / コンパニオン診断 / 病理バイオマーカー / MET / PD-L1 / Companion diagnostic / Tumor heterogeneity / Biomarker / Lung Cancer / 評価尺度 / 理解度 / がん臨床試験 / プロテオミクス解析 / 大腸がん / 薬剤耐性機序 / リン酸化プロテオーム解析 / ROS1 / 分子標的治療薬 / EGFR / RET / ROS / 耐性 / ABCトランスポーター / 耐性機構 / チロシンキナーゼ阻害薬 / 変異 / 獲得耐性 / 分子標的薬 / SEQUENTIAL CHANGE / DYSPLASIA / LOSS OF HETEROZYGOSITY / CHROMATE / INHALATION CARCINOGEN / OCCUPATIONAL CANCER / LUNG CANCER / 経時的変化 / 異形成 / LOH / クロム / 吸入発癌物質 / 職業癌 / 小細胞がん / 遺伝子発現解析 / 分子病理診断 / 網羅的発現解析 / 大細胞神経内分泌癌 / 小細胞癌 / 神経内分泌癌 Less
  • Research Projects

    (8 results)
  • Research Products

    (19 results)
  • Co-Researchers

    (40 People)
  •  Discovery of drug resistant mechnism by kinome analysis using patient derived cultured cells

    • Principal Investigator
      Tomonaga Takeshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor diagnostics
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Intratumoral heterogeneity of lung cancer and its influence on the companion diagnostics

    • Principal Investigator
      Motoi Noriko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      National Cancer Center Japan
  •  Resistance mechanisms to molecular targeted drugs in lung adenocarcinoma

    • Principal Investigator
      Katayama Ryohei
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Evaluation of patients' understanding regarding caner clinical trials

    • Principal Investigator
      Kohara Izumi
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Clinical nursing
    • Research Institution
      Jichi Medical University
  •  Peripheral location, TTF-1 expression and prognosis of SCLCPrincipal Investigator

    • Principal Investigator
      NISHIO Makoto
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor diagnosis
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Comprehensive analysis of pulmonary neuroendocrine carcinoma, Evaluation of pathologic classification and application for clinical diagnosis

    • Principal Investigator
      MOTOI Noriko
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Predection for sensitivity of gefitinib against Non-small cell lung cancerPrincipal Investigator

    • Principal Investigator
      NISHIO Makoto
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Genetic analyses of bronchogenic, carcinoma arising in ex-chromate workers : researches on sequential change of bronchial dysplastic changes and autopsy cases.

    • Principal Investigator
      SATOH Yukitoshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Japanese Foundation For Cancer Research

All 2017 2016 2015 2014 2013 2012 2009

All Journal Article Presentation

  • [Journal Article] High expression of programmed cell death 1 ligand 1 in lung adenocarcinoma is a poor prognostic factor particularly in smokers and wild-type epidermal growth-factor receptor cases2017

    • Author(s)
      Mori S, Motoi N, Ninomiya H, Matuura Y, Nakao M, Mun M-y, Ikumura S, Nishio M, Morikawa T, Ishikawa Y
    • Journal Title

      Pathol Int

      Volume: 67 Issue: 1 Pages: 37-44

    • DOI

      10.1111/pin.12489

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04714, KAKENHI-PROJECT-15K08373
  • [Journal Article] P-glycoprotein mediates ceritinib resistance in anaplastic lymphoma kinase-rearranged non-small cell lung cancer.2016

    • Author(s)
      Katayama R*, Sakashita T, Yanagitani N, Ninomiya H, Horiike A, Friboulet L, Gainor JF, Motoi N, Dobashi A, Sakata S, Tambo Y, Kitazono S, Sato S, Koike S, Iafrate AJ, Mino-Kenudson M, Ishikawa Y, Shaw AT, Engelman JA, Takeuchi K, Nishio M*, Fujita N*
    • Journal Title

      EBioMedicine

      Volume: 3 Pages: 54-66

    • DOI

      10.1016/j.ebiom.2015.12.009

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14412, KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-25250020, KAKENHI-PROJECT-25710015, KAKENHI-PROJECT-15K08373
  • [Journal Article] EBUS-TBNA as a promising method for the evaluation of tumor PD-L1 expression in lung cancer.2016

    • Author(s)
      Sakakibara R, Inamura K, Tambo Y, et al.
    • Journal Title

      Clinical Lung Cancer.

      Volume: 印刷中 Issue: 5 Pages: 527-534

    • DOI

      10.1016/j.cllc.2016.12.002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08373, KAKENHI-PROJECT-16K08679, KAKENHI-PROJECT-15H04714
  • [Journal Article] A subset of small cell lung cancer with low neuroendocrine expression and good prognosis: a comparison study of surgical and inoperable cases with biopsy.2014

    • Author(s)
      Hamanaka, W., Motoi, N., Ishikawa, S., Ushijima, M., Inamura, K., Hatano, S., Uehara, H., Okumura, S., Nakagawa, K., Nishio, M., Horai, T., Aburatani, H., Matsuura, M., Iwasaki, A., Ishikawa, Y.
    • Journal Title

      Hum. Pathol.

      Volume: 45 (5) Pages: 1045-1056

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501347
  • [Journal Article] Etoposide and cisplatin versus irinotecan and cisplatin in patients with limited-stage small-cell lung cancer treated with etoposide and cisplatin plus concurrent accelerated hyperfractionated thoracic radiotherapy (JCOG0202): a randomised phase 3 study.2014

    • Author(s)
      Kubota, K., Hida, T., Ishikura, S., Mizusawa, J., Nishio, M., Kawahara, M., Yokoyama, A., Imamura, F., Takeda, K., Negoro, S., Harada, M., Okamoto, H., Yamamoto, N., Shinkai, T., Sakai, H., Matsui, K., Nakagawa, K., Shibata, T., Saijo, N., Tamura, T.
    • Journal Title

      Lancet Oncol.

      Volume: 15 (1) Pages: 106-113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501347
  • [Journal Article] Dacomitinib as first-line treatment in patients with clinically or molecularly selected advanced non-small-cell lung cancer: a multicentre, open-label, phase 2 trial.2014

    • Author(s)
      Janne, P. A., Ou, S. H., Kim, D. W., Oxnard, G. R., Martins, R., Kris, M. G., Dunphy, F., Nishio, M., O'Connell, J., Paweletz, C., Taylor, I., Zhang, H., Goldberg, Z., Mok, T.
    • Journal Title

      Lancet Oncol.

      Volume: 15 (13) Pages: 1433-1441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501347
  • [Journal Article] Phase II study of erlotinib for acquired resistance to gefitinib in patients with advanced non-small cell lung cancer.2014

    • Author(s)
      Horiike, A., Yamamoto, N., Tanaka, H., Yanagitani, N., Kudo, K., Ohyanagi, F., Ono, A., Naito, T., Murakami, H., Horai, T., Nishio, M.
    • Journal Title

      Anticancer Res.

      Volume: 34 (4) Pages: 1975-1981

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501347
  • [Journal Article] The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer.2014

    • Author(s)
      Friboulet L, Li N, Katayama R, Lee CC, Gainor JF, Crystal AS, Michellys PY, Awad MM, Yanagitani N, Kim S, Pferdekamper AC, Li J, Kasibhatla S, Sun F, Sun X, Hua S, McNamara P, Mahmood S, Lockerman EL, Fujita N, Nishio M, Harris JL, Shaw AT, Engelman JA
    • Journal Title

      Cancer Discov.

      Volume: 4 Issue: 6 Pages: 662-673

    • DOI

      10.1158/2159-8290.cd-13-0846

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300344, KAKENHI-PROJECT-25710015
  • [Journal Article] The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer.2014

    • Author(s)
      Friboulet, L., Li, N., Katayama, R., Lee, C. C., Gainor, J. F., Crystal, A. S., Michellys, P. Y., Awad, M. M., Yanagitani, N., Kim, S., Pferdekamper, A. C., Li, J., Kasibhatla, S., Sun, F., Sun, X., Hua, S., McNamara, P., Mahmood, S., Lockerman, E. L., Fujita, N., Nishio, M., Harris, J. L., Shaw, A. T., Engelman, J. A.
    • Journal Title

      Cancer Discov.

      Volume: 4 (6) Pages: 662-673

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501347
  • [Presentation] Novel ceritinib resistance mechanisms: new resistant mutation, fibroblast growth factor receptor 3 overexpression and cMET amplification-mediated ceritinib resistance2015

    • Author(s)
      Ryohei Katayama, Takuya Sakashita, Noriko Yanagitani, Kengo Takeuchi, Makoto Nishio, Naoya Fujita
    • Organizer
      AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
    • Place of Presentation
      米国、ボストン
    • Year and Date
      2015-11-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25710015
  • [Presentation] 培養細胞株と患者検体を用いたALK阻害薬耐性機構の解析2015

    • Author(s)
      片山量平、小池清恵、西尾誠人、藤田直也
    • Organizer
      第19回 日本がん分子標的治療学会
    • Place of Presentation
      松山全日空ホテル、愛媛
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-25710015
  • [Presentation] Resistance mechanisms to ALK inhibitors2015

    • Author(s)
      Ryohei Katayama, Noriko Yanagitani, Sumie Koike, Takuya Sakashita, Satoru Kitazono, Makoto Nishio, Yasushi Okuno, Jeffrey A. Engelman, Alice T. Shaw, Naoya Fujita
    • Organizer
      第106回 アメリカ癌学会学術総会
    • Place of Presentation
      米国、フィラデルフィア
    • Year and Date
      2015-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25710015
  • [Presentation] Characterization of the ALK-TKI resistant cells mediated by secondary mutations or bypass pathway activation.2015

    • Author(s)
      小池清恵、坂下卓也、西尾誠人、藤田直也、片山量平
    • Organizer
      第74回 日本癌学会総会
    • Place of Presentation
      名古屋国際会議場、名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25710015
  • [Presentation] Prophylactic cranial irradiation (PCI) has a detrimental effect on the overall survival (OS) of patients (pts) with extensive disease small cell lung cancer (ED-SCLC): Results of a Japanese randomized phase III trial.2014

    • Author(s)
      Seto, T., Takahashi, T., Yamanaka, T., Harada, H., Nokihara, H., Saka, H., Nishio, M., Nakagawa, K., Takayama, K., Ishimoto, O., Takeda, K., Yoshioka, H., Tachihara, M., Sakai, H., Goto, K., Yamamoto, N.
    • Organizer
      ASCO 50th Annual Meeting
    • Place of Presentation
      Chicago, USA.
    • Year and Date
      2014-05-30
    • Data Source
      KAKENHI-PROJECT-24501347
  • [Presentation] A randomized phase III study of cisplatin (CDDP), etoposide (ETOP) and irinotecan versus topotecan as second-line chemotherapy in patients with sensitive relapsed small-cell lung cancer (SCLC): Japan Clinical Oncology Group study JCOG0605.2014

    • Author(s)
      Goto, K., Ohe, Y., Seto, T., Takahashi, T., Nakagawa, K., Yamamoto, N., Yokoyama, A., Takeda, K., Nishio, M., Mori, K., Satouchi, M., Hida, T., Kudoh, S., Nogami, N., Imamura, F., Kiura, K., Okamoto, H., Sawa, T., Shibata, T., Tamura, T.
    • Organizer
      ASCO 50th Annual Meeting
    • Place of Presentation
      Chicago, USA.
    • Year and Date
      2014-05-30
    • Data Source
      KAKENHI-PROJECT-24501347
  • [Presentation] 末梢型小細胞肺がんは中枢型に比べ予後不良で、遺伝子発現プロファイルが異なる2013

    • Author(s)
      宮内栄作、齋藤雄一、二宮浩範、 元井紀子、西尾誠人、奥村栄、 石川雄一
    • Organizer
      第54回日本肺癌学会総会
    • Place of Presentation
      ホテルニューオータニ東京
    • Data Source
      KAKENHI-PROJECT-24501347
  • [Presentation] Primary location of small cell lung cancer (SCLC) and TTF-1 expression: are most SCLCs really of hilar origin?2012

    • Author(s)
      Eisaku Miyauchi, Hiroshi Ono, Hironori Ninomiya, Kentaro Inamura, Noriko Motoi, Makoto Nishio, Sakae Okumura, Yuichi Ishikawa.
    • Organizer
      3rd European Lung Cancer Conference (ELCC)
    • Place of Presentation
      Geneva, Switzerland
    • Data Source
      KAKENHI-PROJECT-24501347
  • [Presentation] 小細胞肺がんの層別化の試み-発生起源の再検討と発がん機構に注目して-2012

    • Author(s)
      宮内栄作、齋藤雄一、二宮浩範、元井紀子、西尾誠人、奥村栄、石川雄一
    • Organizer
      第53回日本肺癌学会総会
    • Place of Presentation
      岡山コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-24501347
  • [Presentation] A subset of small cell lung cancer with low expression of neuroendocrine markers links to a good prognosis : a so far unrecognized subtype.2009

    • Author(s)
      Hamanaka W, Motoi N, Okumura S, Nakagawa K, Nishio M, Horai T, et al.
    • Organizer
      13th World Conference on Lung Cancer(Journal of Thoracic Oncology, 4 (9) Suppl.1 ; 2009.p.S466).
    • Place of Presentation
      San Francisco, CA, USA
    • Data Source
      KAKENHI-PROJECT-20590358
  • 1.  ISHIKAWA Yuichi (80222975)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 5 results
  • 2.  MOTOI Noriko (70292878)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  NAKAGAWA Ken (60085595)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  SATOH Yukitoshi (90321637)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  Katayama Ryohei (60435542)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 6.  MATSUURA Masaaki (40173794)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  SHIMOJI Takashi (40370150)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YANAGITANI Noriko (60400785)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  KITAZONO Satoru (90527863)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  Tomonaga Takeshi (80227644)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Kohara Izumi (80266642)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TAKAHASHI Syunji (90221358)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TAHARA Makoto (50523198)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TASHIRO Shimon (50548550)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  FUJITA Takashi (00630849)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  OKUMURA Sakae (40465935)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  藤田 直也 (20280951)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 18.  長山 聡 (70362499)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  藤原 寛行 (50316535)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  藤井 博文 (80438613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  本田 芳香 (80307123)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  宋 菜緒子 (40649125)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  吉村 健一 (30415517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  YAMAMOTO Seiichiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  KATAGI Miho
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  USHIROZAWA Nobuko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  NAKAHAMA Hiroko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  ICHIMURA Tomoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  HAGA Yoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  SAITO Yumiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  NARITA Yoshiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  SATO Satoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  YANAI Kai
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  YAMANAKA Tokiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  TARUKI Masako
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  MIYAZAKI Chieko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  SHIBA Satomi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  TANAKA Yumiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  SANO Aika
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  AMEMIYA Yasue
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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