Kimura Makoto 木村誠

… Alternative Names

木村誠キムラマコト

KIMURA Makoto 木村誠

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Researcher Number	00290891
Other IDs	https://orcid.org/0000-0003-0868-5334
Affiliation (Current)	2024: 国立研究開発法人理化学研究所, 開拓研究本部, 上級研究員
Affiliation (based on the past Project Information) *help	2018 – 2023: 国立研究開発法人理化学研究所, 開拓研究本部, 専任研究員 2015 – 2017: 国立研究開発法人理化学研究所, 今本細胞核機能研究室, 専任研究員 2010: 独立行政法人理化学研究所, 今本細胞核機能研究室, 専任研究員 2006: RIKEN, Gene Engineering Division, Senior researcher, 遺伝子材料研究室, 専任研究員 2004 – 2006: RIKEN, Gene Engineering Division, Senior Research Scientist, 遺伝子材料開発室, 先任研究員 2003: 独立行政法人理化学研究所, 遺伝子材料開発室, 研究員 1997 – 2002: 国立遺伝学研究所, 分子遺伝研究系, 助手
Review Section/Research Field	Principal Investigator Molecular biology / Basic Section 44010:Cell biology-related / Cell biology / Molecular biology Except Principal Investigator Basic Section 44010:Cell biology-related / Developmental biology / Cell biology / Biological Sciences
Keywords	Principal Investigator 分裂酵母 / 蛋白質相互作用 / RNAポリメラーゼII / RNAポリメラーゼ / ホスファターゼ / 転写因子 / バキュロウイルス / 転写調節 / importin / 核輸送 … More / Rpb4 / TFIIF / リン酸化 / 緑色蛍光蛋白質 / 核-細胞質間蛋白質輸送 / 細胞分化 / プロテオミクス / キーワード / SILAC / actin / fission yeast / Tfg3 / CTD phosphatase Fcp1 / RNA polymerase II / 蛋白質リン酸化 / 蛋白質複合体 / アクチン / TFG / CTDホスファターゼFCP1 / エピトープタグ / マスフィンガープリント / バキュロウイルスベクター / ファーウェスタン解析 / 架橋剤 / 蛋白質間相互作用 / 転写制御 … More Except Principal Investigator 核-細胞質間輸送 / 定量的プロテオミクス / evolutionary trace / Importin α / Importin β / 細胞機能 / 基質特異的認識 / 細胞機能制御 / Importin alpha / Importin beta / Adenovirusvector / Cell-differentiation / Histone deacetylation / Remodeling / Transcription factor / Histone acetylation / Histone caperon / Chromatin / アデノウイルスベクター / 分化制御 / リモデリング / ヒストンシャペロン / 転写因子 / ヒストン脱アセチル化 / ヒストンアセチル化 / クロマチン / 質量分析法 / 安定同位体標識 / 輸送再構成系 / セミインタクト細胞 / 核膜孔複合体 / 低分子量GTPase Ran / インポーティン / ヒストン修飾能 / 増殖制御 / AP-1リプレッサー / JDP2 / 分化誘導 / レチノイン酸 / c-jun遺伝子 / 胚性腫瘍細胞 Less

Division of cellular function of nuclear transport pathways
- Principal Investigator
  
  今本尚子
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Institute of Physical and Chemical Research
Rolls of the importin beta family nucleocytoplasmic transport receptors in cellular regulation systemsPrincipal Investigator
- Principal Investigator
  
  Kimura Makoto
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Institute of Physical and Chemical Research
Elucidation of cellular processes that involve the importin family nucleocytoplasmic transport receptorsPrincipal Investigator
- Principal Investigator
  
  Kimura Makoto
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Institute of Physical and Chemical Research
核ー細胞質間輸送システムの統合的解析に向けた基盤作り
- Principal Investigator
  
  今本尚子
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  The Institute of Physical and Chemical Research
Chromatin dynamics and modulated cell-differentiation
- Principal Investigator
  
  YOKOYAMA Kazunari
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Developmental biology
- Research Institution
  RIKEN
胚性腫瘍細胞の分化制御とヒストン修飾
- Principal Investigator
  
  YOKOYAMA Kazunari
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Analysis of regulation mechanisms of the fission yeast RNA polymerase IIPrincipal Investigator
- Principal Investigator
  
  KIMURA Makoto
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  RIKEN
CTDホスファターゼFCP1によるRNAポリメラーゼIIの制御機構の解析Principal Investigator
- Principal Investigator
  
  木村誠
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  National Institute of Genetics
RNAポリメラーゼIIを中心とした蛋白質相互作用による転写調節機構の解析Principal Investigator
- Principal Investigator
  
  木村誠
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Institute of Genetics
RNAポリメラーゼIIを中心とした蛋白質相互作用による転写調節機構の解析Principal Investigator
- Principal Investigator
  
  木村誠
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Institute of Genetics
分裂酵母RNAポリメラーゼIIの遺伝子組換え蛋白質による再構成Principal Investigator
- Principal Investigator
  
  木村誠
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  National Institute of Genetics
RNAポリメラーゼIIと相互作用をもつ蛋白質因子の単離とその機能の解析Principal Investigator
- Principal Investigator
  
  木村誠
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Institute of Genetics
分裂酵母RNAポリメラーゼIIサブユニットを中心としたタンパク質相互作用の解析Principal Investigator
- Principal Investigator
  
  木村誠
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  National Institute of Genetics

All 2021 2020 2017 2015 2007 2005 2004

All Journal Article Presentation

[Journal Article] Distinct mutations in importin-β family nucleocytoplasmic transport receptors transportin-SR and importin-13 affect specific cargo binding2021
- Author(s)
  Kimura M, Imai K, Morinaka Y, Hosono-Sakuma Y, Horton P, Imamoto N
- Journal Title
  
  Sci Rep.
  
  Volume: 11 Issue: 1 Pages: 15649-15649
- DOI
  10.1038/s41598-021-94948-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11543, KAKENHI-PROJECT-18H02442, KAKENHI-PROJECT-18K06235, KAKENHI-PROJECT-21H02482
[Journal Article] Nuclear import of IER5 is mediated by a classical bipartite nuclear localization signal and is required for HSF1 full activation2020
- Author(s)
  Shotaro Yamano, Makoto Kimura, Yu Chen, Naoko Imamoto, Rieko Ohki
- Journal Title
  
  Experimental Cell Research
  
  Volume: 386 Issue: 1 Pages: 111686-111686
- DOI
  10.1016/j.yexcr.2019.111686
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06235, KAKENHI-INTERNATIONAL-15K21744, KAKENHI-PLANNED-15H05929, KAKENHI-PROJECT-17H03587, KAKENHI-PROJECT-18H02442, KAKENHI-PROJECT-18F18758, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K16732
[Journal Article] Extensive cargo identification reveals distinct biological roles of the 12 Importin pathways2017
- Author(s)
  Kimura, M., Morinaka, Y., Imai, K., Kose, S, Horton, P, Imamoto, N
- Journal Title
  
  eLife
  
  Volume: 6
- DOI
  10.7554/elife.21184
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-15H05929, KAKENHI-PROJECT-26440109, KAKENHI-PROJECT-15K07064
[Journal Article] JDP2 suppresses adipocyte differentiation by regulating histone acetylation.2007
- Author(s)
  Nakade, K., Pan, J., Yoshiki, A., Ugai, H., Kimura, M., Liu, B., Li, H., Obata, Y., Iwama, M., Itohara, S., Murata, T., Yokoyama, K.
- Journal Title
  
  Cell Death and Differentiation (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17370084
[Journal Article] Studies of Schizosaccharomyces pombe TFIIE indicate conformational and functional changes in RNA polymerase II at transcription initiation.2005
- Author(s)
  Kazuhiro Hayashi, Tomomichi Watanabe, Aki Tanaka, Tadashi Furumoto, Chiaki Sato-Tsuchiya, Makoto Kimura, Masayuki Yokoi, Akira Ishihama, Fumio Hanaoka, Yoshiaki Ohkuma
- Journal Title
  
  Genes to Cells 10
  
  Pages: 207-225
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570148
[Journal Article] Glyceraldehyde-3-phosphate dehydrogenase and actin associate with RNA polymerase II and interacts with its Rpb7 subunit.2005
- Author(s)
  Hiroshi Mitsuzawa, Makoto Kimura, Emi Kanda, Akira Ishihama
- Journal Title
  
  FEBS Letters 579
  
  Pages: 48-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570148
[Journal Article] High-temperature induction of male sterility during barley (Hordeum vulgare L.) anther development is mediated by transcriptional inhibition.2005
- Author(s)
  Mafumi Abiko, Kenichi Akibayashi, Tadashi Sakata, Makoto Kimura, Makoto Kihara, Kazutoshi Itoh, Erika Asamizu, Shusei Sato, Hideyiki Takahashi, Atsushi Higashitani
- Journal Title
  
  Sexual Plant Reproduction 18
  
  Pages: 91-100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570148
[Journal Article] Purification of infectious adenovirus in two hours by ultracentrifugation and tangential flow filtration.2005
- Author(s)
  Ugai, H, Yamasaki, T, Hirose, M, Inabe, K, Kujime, Y, Terashima, M, Liu, B, Tang, H, Zhao, M, Murata, T, Kimura, M, Pan, J, Obata, Y, Hamada, H, Yokoyama, K.
- Journal Title
  
  Biochem. Biophys. Res. Commu. 331
  
  Pages: 1053-1060
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17370084
[Journal Article] A database of recombinant viruses and recombinant viral vectors available from the RIKEN DNA bank.2005
- Author(s)
  Ugai, H, Murata, T, Nagamura, Y, Ugawa, Y, Suzuki, E, Nakata, H, Kujime, Y, Inamoto, S, Hirose, M, Inabe, K, Terashima, M, Yamasaki, T, Liu, B, Nakade, K, Pan, J, Kimura, M, Saito, I, Hamada, H, Obata, Y, Yokoyama, K.
- Journal Title
  
  J. Gene Med. 7
  
  Pages: 1148-1157
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17370084
[Journal Article] Tfg3, a subunit of the general transcription factor TFIIF in Schizosaccharomyces pombe, functions under stress conditions.2004
- Author(s)
  Makoto Kimura
- Journal Title
  
  Nucleic Acids Research 32
  
  Pages: 6706-6715
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570148
[Journal Article] Tfg3, a subunit of the general transcription factor TFIIF in Schizosaccharomyces pombe, functions under stress conditions.2004
- Author(s)
  Makoto Kimura, Akira Ishihama
- Journal Title
  
  Nucleic Acids Research 32
  
  Pages: 6706-6715
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570148
[Journal Article] RNA polymerases.2004
- Author(s)
  Makoto Kimura
- Journal Title
  
  Illust-map of the transcription for understanding by the keywards. (in Japanese) (edited by Takaaki Tamura) (Yodosha Tokyo)
  
  Pages: 19-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570148
[Journal Article] Transcription apparatus of S.pombe : RNA polymerases and accessory factors.2004
- Author(s)
  Makoto Kimura, Hiroshi Mitsuzawa, Akira Ishihama
- Journal Title
  
  Molecular Biology of Schizosacharimyces pombe. (edited by Richard Egel) (Springer-Verlag Berlin/Heidelberg/New York)
  
  Pages: 329-342
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570148
[Journal Article] Tfg3, a subunit of the general transcription factor TFIIF in Schizosaccharomyces pombe, functions under stress conditions2004
- Author(s)
  Makoto Kimura
- Journal Title
  
  Nucleic Acids Research 32・22
  
  Pages: 6706-6715
- Data Source
  KAKENHI-PROJECT-15570148
[Presentation] 核-細胞質間輸送の多様性と役割分担2021
- Author(s)
  今本尚子、木村誠、今井賢一郎
- Organizer
  第73回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-18K06235
[Presentation] 細胞質から核への蛋白質輸送を担う12種類のimportin-βファミリー輸送因子の基質の同定2017
- Author(s)
  木村誠、森中祐理子、今井賢一郎、小瀬真吾、Paul Horton、今本尚子
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K07064
[Presentation] 細胞質から核への蛋白質輸送を担う12種類のimportin-βファミリー輸送因子の基質の大規模同定2017
- Author(s)
  木村誠, 森中有理子, 今井賢一郎, 小瀬真吾, Paul Horton, 今本尚子
- Organizer
  第34回染色体ワークショップ・第14回核ダイナミクス研究会
- Place of Presentation
  オークラアカデミアパークホテル（千葉県木更津市）
- Year and Date
  2017-01-12
- Data Source
  KAKENHI-PROJECT-15K07064
[Presentation] Importin-βファミリーが構成するヒト細胞の核内輸送経路を網羅した基質蛋白質の解析2017
- Author(s)
  今本尚子, 木村誠
- Organizer
  大阪大学蛋白質研究所セミナー
- Place of Presentation
  大阪大学蛋白質研究所（大阪府吹田市）
- Year and Date
  2017-03-21
- Invited
- Data Source
  KAKENHI-PROJECT-15K07064
[Presentation] SILAC法と蛋白質核輸送再構成系によるimportin-βファミリー輸送因子の輸送基質の大規模同定2015
- Author(s)
  木村誠、小瀬真吾、今本尚子
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会
- Place of Presentation
  神戸国際展示場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K07064

1. YOKOYAMA Kazunari (80182707)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. MURATA Takehide (50281621)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. 今本尚子 (20202145)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. PAN Jianzhi (80373356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OGURA Atsuo (20194524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 鵜飼英世 (00344060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小瀬真吾 (90333278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IMAI Kenichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. PAN Jhanzhi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 横山一成

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Kimura Makoto 木村 誠

木村 誠 キムラ マコト

KIMURA Makoto 木村 誠

Research Projects

Research Products

Co-Researchers

Division of cellular function of nuclear transport pathways

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Rolls of the importin beta family nucleocytoplasmic transport receptors in cellular regulation systemsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of cellular processes that involve the importin family nucleocytoplasmic transport receptorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

核ー細胞質間輸送システムの統合的解析に向けた基盤作り

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Chromatin dynamics and modulated cell-differentiation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

胚性腫瘍細胞の分化制御とヒストン修飾

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of regulation mechanisms of the fission yeast RNA polymerase IIPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CTDホスファターゼFCP1によるRNAポリメラーゼIIの制御機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

RNAポリメラーゼIIを中心とした蛋白質相互作用による転写調節機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

RNAポリメラーゼIIを中心とした蛋白質相互作用による転写調節機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

分裂酵母RNAポリメラーゼIIの遺伝子組換え蛋白質による再構成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

RNAポリメラーゼIIと相互作用をもつ蛋白質因子の単離とその機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

分裂酵母RNAポリメラーゼIIサブユニットを中心としたタンパク質相互作用の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Kimura Makoto 木村誠

木村誠キムラマコト

KIMURA Makoto 木村誠