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Kimura Makoto  木村 誠

… Alternative Names

木村 誠  キムラ マコト

KIMURA Makoto  木村 誠

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Researcher Number 00290891
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-0868-5334
Affiliation (Current) 2022: 国立研究開発法人理化学研究所, 開拓研究本部, 専任研究員
Affiliation (based on the past Project Information) *help 2018 – 2022: 国立研究開発法人理化学研究所, 開拓研究本部, 専任研究員
2015 – 2017: 国立研究開発法人理化学研究所, 今本細胞核機能研究室, 専任研究員
2010: 独立行政法人理化学研究所, 今本細胞核機能研究室, 専任研究員
2006: RIKEN, Gene Engineering Division, Senior researcher, 遺伝子材料研究室, 専任研究員
2004 – 2006: RIKEN, Gene Engineering Division, Senior Research Scientist, 遺伝子材料開発室, 先任研究員
2003: 独立行政法人理化学研究所, 遺伝子材料開発室, 研究員
1997 – 2002: 国立遺伝学研究所, 分子遺伝研究系, 助手
Review Section/Research Field
Principal Investigator
Molecular biology / Molecular biology / Cell biology / Basic Section 44010:Cell biology-related
Except Principal Investigator
Biological Sciences / Cell biology / Developmental biology / Basic Section 44010:Cell biology-related
Keywords
Principal Investigator
蛋白質相互作用 / 分裂酵母 / RNAポリメラーゼII / RNAポリメラーゼ / 転写調節 / バキュロウイルス / 転写因子 / ホスファターゼ / 緑色蛍光蛋白質 / リン酸化 … More / TFIIF / Rpb4 / 核輸送 / importin / 転写制御 / 蛋白質間相互作用 / 架橋剤 / ファーウェスタン解析 / バキュロウイルスベクター / マスフィンガープリント / エピトープタグ / CTDホスファターゼFCP1 / TFG / アクチン / 蛋白質複合体 / 蛋白質リン酸化 / RNA polymerase II / CTD phosphatase Fcp1 / Tfg3 / fission yeast / actin / SILAC / キーワード / プロテオミクス / 細胞分化 / 核-細胞質間蛋白質輸送 … More
Except Principal Investigator
核-細胞質間輸送 / 胚性腫瘍細胞 / c-jun遺伝子 / レチノイン酸 / 分化誘導 / JDP2 / AP-1リプレッサー / 増殖制御 / ヒストン修飾能 / インポーティン / 低分子量GTPase Ran / 核膜孔複合体 / セミインタクト細胞 / 輸送再構成系 / 安定同位体標識 / 質量分析法 / クロマチン / ヒストンアセチル化 / ヒストン脱アセチル化 / 転写因子 / ヒストンシャペロン / リモデリング / 分化制御 / アデノウイルスベクター / Chromatin / Histone caperon / Histone acetylation / Transcription factor / Remodeling / Histone deacetylation / Cell-differentiation / Adenovirusvector / Importin beta / Importin alpha / 細胞機能制御 / Importin β / Importin α / evolutionary trace / 定量的プロテオミクス Less
  • Research Projects

    (13 results)
  • Research Products

    (19 results)
  • Co-Researchers

    (11 People)
  •  Division of cellular function of nuclear transport pathways

    • Principal Investigator
      今本 尚子
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  Importinβファミリー核-細胞質間輸送因子の調節による細胞制御機構の解析Principal Investigator

    • Principal Investigator
      木村 誠
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  Elucidation of cellular processes that involve the importin family nucleocytoplasmic transport receptorsPrincipal Investigator

    • Principal Investigator
      Kimura Makoto
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Institute of Physical and Chemical Research
  •  核ー細胞質間輸送システムの統合的解析に向けた基盤作り

    • Principal Investigator
      今本 尚子
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Chromatin dynamics and modulated cell-differentiation

    • Principal Investigator
      YOKOYAMA Kazunari
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Developmental biology
    • Research Institution
      RIKEN
  •  胚性腫瘍細胞の分化制御とヒストン修飾

    • Principal Investigator
      YOKOYAMA Kazunari
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Analysis of regulation mechanisms of the fission yeast RNA polymerase IIPrincipal Investigator

    • Principal Investigator
      KIMURA Makoto
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      RIKEN
  •  CTDホスファターゼFCP1によるRNAポリメラーゼIIの制御機構の解析Principal Investigator

    • Principal Investigator
      木村 誠
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Molecular biology
    • Research Institution
      National Institute of Genetics
  •  RNAポリメラーゼIIを中心とした蛋白質相互作用による転写調節機構の解析Principal Investigator

    • Principal Investigator
      木村 誠
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      National Institute of Genetics
  •  RNAポリメラーゼIIを中心とした蛋白質相互作用による転写調節機構の解析Principal Investigator

    • Principal Investigator
      木村 誠
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      National Institute of Genetics
  •  分裂酵母RNAポリメラーゼIIの遺伝子組換え蛋白質による再構成Principal Investigator

    • Principal Investigator
      木村 誠
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      National Institute of Genetics
  •  RNAポリメラーゼIIと相互作用をもつ蛋白質因子の単離とその機能の解析Principal Investigator

    • Principal Investigator
      木村 誠
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      National Institute of Genetics
  •  分裂酵母RNAポリメラーゼIIサブユニットを中心としたタンパク質相互作用の解析Principal Investigator

    • Principal Investigator
      木村 誠
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      National Institute of Genetics

All 2021 2020 2017 2015 2007 2005 2004

All Journal Article Presentation

  • [Journal Article] Distinct mutations in importin-β family nucleocytoplasmic transport receptors transportin-SR and importin-13 affect specific cargo binding2021

    • Author(s)
      Kimura M, Imai K, Morinaka Y, Hosono-Sakuma Y, Horton P, Imamoto N
    • Journal Title

      Scientific Reports

      Volume: 11 Pages: 15649-15649

    • DOI

      10.1038/s41598-021-94948-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K11543, KAKENHI-PROJECT-18H02442, KAKENHI-PROJECT-18K06235
  • [Journal Article] Nuclear import of IER5 is mediated by a classical bipartite nuclear localization signal and is required for HSF1 full activation.2020

    • Author(s)
      Shotaro Yamano, Makoto Kimura, Yu Chen, Naoko Imamoto* and Rieko Ohki*.
    • Journal Title

      Experimental Cell Research

      Volume: 386 Issue: 1 Pages: 111686-111686

    • DOI

      10.1016/j.yexcr.2019.111686

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06235, KAKENHI-INTERNATIONAL-15K21744, KAKENHI-PLANNED-15H05929, KAKENHI-PROJECT-17H03587, KAKENHI-PROJECT-18H02442, KAKENHI-PROJECT-18F18758, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K16732
  • [Journal Article] Extensive cargo identification reveals distinct biological roles of the 12 importin pathways2017

    • Author(s)
      Kimura, M., Morinaka, Y., Imai, K., Kose, S, Horton, P, Imamoto, N
    • Journal Title

      Elife

      Volume: 6

    • DOI

      10.7554/elife.21184

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05929, KAKENHI-PROJECT-26440109, KAKENHI-PROJECT-15K07064
  • [Journal Article] JDP2 suppresses adipocyte differentiation by regulating histone acetylation.2007

    • Author(s)
      Nakade, K., Pan, J., Yoshiki, A., Ugai, H., Kimura, M., Liu, B., Li, H., Obata, Y., Iwama, M., Itohara, S., Murata, T., Yokoyama, K.
    • Journal Title

      Cell Death and Differentiation (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17370084
  • [Journal Article] Studies of Schizosaccharomyces pombe TFIIE indicate conformational and functional changes in RNA polymerase II at transcription initiation.2005

    • Author(s)
      Kazuhiro Hayashi, Tomomichi Watanabe, Aki Tanaka, Tadashi Furumoto, Chiaki Sato-Tsuchiya, Makoto Kimura, Masayuki Yokoi, Akira Ishihama, Fumio Hanaoka, Yoshiaki Ohkuma
    • Journal Title

      Genes to Cells 10

      Pages: 207-225

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570148
  • [Journal Article] Glyceraldehyde-3-phosphate dehydrogenase and actin associate with RNA polymerase II and interacts with its Rpb7 subunit.2005

    • Author(s)
      Hiroshi Mitsuzawa, Makoto Kimura, Emi Kanda, Akira Ishihama
    • Journal Title

      FEBS Letters 579

      Pages: 48-52

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570148
  • [Journal Article] High-temperature induction of male sterility during barley (Hordeum vulgare L.) anther development is mediated by transcriptional inhibition.2005

    • Author(s)
      Mafumi Abiko, Kenichi Akibayashi, Tadashi Sakata, Makoto Kimura, Makoto Kihara, Kazutoshi Itoh, Erika Asamizu, Shusei Sato, Hideyiki Takahashi, Atsushi Higashitani
    • Journal Title

      Sexual Plant Reproduction 18

      Pages: 91-100

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570148
  • [Journal Article] Purification of infectious adenovirus in two hours by ultracentrifugation and tangential flow filtration.2005

    • Author(s)
      Ugai, H, Yamasaki, T, Hirose, M, Inabe, K, Kujime, Y, Terashima, M, Liu, B, Tang, H, Zhao, M, Murata, T, Kimura, M, Pan, J, Obata, Y, Hamada, H, Yokoyama, K.
    • Journal Title

      Biochem. Biophys. Res. Commu. 331

      Pages: 1053-1060

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17370084
  • [Journal Article] A database of recombinant viruses and recombinant viral vectors available from the RIKEN DNA bank.2005

    • Author(s)
      Ugai, H, Murata, T, Nagamura, Y, Ugawa, Y, Suzuki, E, Nakata, H, Kujime, Y, Inamoto, S, Hirose, M, Inabe, K, Terashima, M, Yamasaki, T, Liu, B, Nakade, K, Pan, J, Kimura, M, Saito, I, Hamada, H, Obata, Y, Yokoyama, K.
    • Journal Title

      J. Gene Med. 7

      Pages: 1148-1157

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17370084
  • [Journal Article] Tfg3, a subunit of the general transcription factor TFIIF in Schizosaccharomyces pombe, functions under stress conditions.2004

    • Author(s)
      Makoto Kimura
    • Journal Title

      Nucleic Acids Research 32

      Pages: 6706-6715

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15570148
  • [Journal Article] Tfg3, a subunit of the general transcription factor TFIIF in Schizosaccharomyces pombe, functions under stress conditions.2004

    • Author(s)
      Makoto Kimura, Akira Ishihama
    • Journal Title

      Nucleic Acids Research 32

      Pages: 6706-6715

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570148
  • [Journal Article] RNA polymerases.2004

    • Author(s)
      Makoto Kimura
    • Journal Title

      Illust-map of the transcription for understanding by the keywards. (in Japanese) (edited by Takaaki Tamura) (Yodosha Tokyo)

      Pages: 19-26

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570148
  • [Journal Article] Transcription apparatus of S.pombe : RNA polymerases and accessory factors.2004

    • Author(s)
      Makoto Kimura, Hiroshi Mitsuzawa, Akira Ishihama
    • Journal Title

      Molecular Biology of Schizosacharimyces pombe. (edited by Richard Egel) (Springer-Verlag Berlin/Heidelberg/New York)

      Pages: 329-342

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570148
  • [Journal Article] Tfg3, a subunit of the general transcription factor TFIIF in Schizosaccharomyces pombe, functions under stress conditions2004

    • Author(s)
      Makoto Kimura
    • Journal Title

      Nucleic Acids Research 32・22

      Pages: 6706-6715

    • Data Source
      KAKENHI-PROJECT-15570148
  • [Presentation] 核-細胞質間輸送の多様性と役割分担2021

    • Author(s)
      今本尚子、木村誠、今井賢一郎
    • Organizer
      第73回日本細胞生物学会
    • Data Source
      KAKENHI-PROJECT-18K06235
  • [Presentation] 細胞質から核への蛋白質輸送を担う12種類のimportin-βファミリー輸送因子の基質の同定2017

    • Author(s)
      木村誠、森中祐理子、今井賢一郎、小瀬真吾、Paul Horton、今本尚子
    • Organizer
      生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-15K07064
  • [Presentation] 細胞質から核への蛋白質輸送を担う12種類のimportin-βファミリー輸送因子の基質の大規模同定2017

    • Author(s)
      木村誠, 森中有理子, 今井賢一郎, 小瀬真吾, Paul Horton, 今本尚子
    • Organizer
      第34回染色体ワークショップ・第14回核ダイナミクス研究会
    • Place of Presentation
      オークラアカデミアパークホテル(千葉県木更津市)
    • Year and Date
      2017-01-12
    • Data Source
      KAKENHI-PROJECT-15K07064
  • [Presentation] Importin-βファミリーが構成するヒト細胞の核内輸送経路を網羅した基質蛋白質の解析2017

    • Author(s)
      今本尚子, 木村誠
    • Organizer
      大阪大学蛋白質研究所セミナー
    • Place of Presentation
      大阪大学蛋白質研究所(大阪府吹田市)
    • Year and Date
      2017-03-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K07064
  • [Presentation] SILAC法と蛋白質核輸送再構成系によるimportin-βファミリー輸送因子の輸送基質の大規模同定2015

    • Author(s)
      木村誠、小瀬真吾、今本尚子
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会
    • Place of Presentation
      神戸国際展示場(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K07064
  • 1.  YOKOYAMA Kazunari (80182707)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  MURATA Takehide (50281621)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 3.  今本 尚子 (20202145)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  PAN Jianzhi (80373356)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  OGURA Atsuo (20194524)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  鵜飼 英世 (00344060)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  小瀬 真吾 (90333278)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  IMAI Kenichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  OHKI Rieko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  PAN Jhanzhi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 11.  横山 一成
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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