KUROOKA Hisanori 黒岡尚徳

… Alternative Names

黒岡尚徳クロオカヒサノリ

Less

Researcher Number	00293879
Other IDs
Affiliation (Current)	2025: 相模女子大学, 栄養科学部, 教授
Affiliation (based on the past Project Information) *help	2016 – 2023: 相模女子大学, 栄養科学部, 教授 2014 – 2016: 福井大学, 医学部, 准教授 2008 – 2012: University of Fukui, 医学部, 准教授 2004 – 2006: University of Fukui, Department of Molecular Genetics, Associate Professor, 医学部, 助教授 2000: 京大, 医学(系)研究科, 助手 … More 2000: Kyoto Univ., Grad.Sch.Med., Assistant Prof., 医学研究科, 助手 1999: 京都大学, 大学院・医学研究科, 助手 1998: 京都大学, 医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Functional biochemistry / General medical chemistry / Molecular biology Except Principal Investigator Pathological medical chemistry / Basic Section 53010:Gastroenterology-related / General medical chemistry / Biological Sciences / Immunology
Keywords	Principal Investigator 転写抑制 / Ets型転写因子 / 初期応答遺伝子 / 有毒微量元素 / Id3 / NES活性 / HLHタンバク質 / ヘテロ二量体 / Eタンパク質 / 過酸化水素水 … More / HLHタンパク質 / ホモ多量体 / 酸化ストレス / システイン / レドックスシグナル / ジスルフィド結合 / ヒ素 / 細胞内局在 / Id / green fluorescence protein / Id1 / Id2 / 細胞内局在制御 / nucleo-cytoplasmic shuttling / nuclear export signal / Idタンパク質ファミリー / bHLHタンパク質 / Delta / カルパイン / Lactacystin / プロテアソーム阻害剤 / MG132 / プロテアーゼ阻害剤 / processing / Notch … More Except Principal Investigator Id2 / 転写因子 / 細胞分化 / 転写調節因子 / B細胞 / 増殖制御 / 発生分化 / 遺伝子発現 / 消化管 / 腸上皮化生 / がん / 消化管上皮 / 腫瘍免疫 / 自己免疫疾患 / 慢性炎症 / growth control / cell differentiation / サイクリン / 遺伝子欠損マウス / 乳腺 / 乳腺上皮細胞 / 発現制御 / 細胞・組織 / 細胞増殖 / 癌 / 遺伝子 / Stat / 遺伝子ネットワーク / 運命決定 / 上皮細胞 / 異所性上皮 / 腸上皮 / 胃上皮 / 上皮 / 分化 / 代謝 / クラススイッチ組み換え / ミトコンドリア / 形質細胞分化 / クラススイッチ組換え / Differentiation / Metabolism / Mitochondria / B cell / development / immediate early gene / 参謀分化 / 発生・分化 / 早期応答遺伝子 / intracellular localization / hydronephrosis / mammary epithelial cells / transcription factor / 腸上皮間リンパ球 / 細胞内局在 / 水腎症 / Transcriptional regulator / Network / Proliferation / Cellular differentiatiom / Gene expression / Cancer / Gene / CDKインヒビター / 増殖 / サイクリンD1 / 癌抑制因子 / EBPβ / C / ネットワーク / retrovirus / transcriptional coactivator / histone acetylation / DNA recombination / signal transduction / γδT cell / cytokine receptor / レトロウィルス / STAT / レトロウイルス / 転写共役因子 / ヒストンアセチル化 / DNA組換え / シグナル伝達 / γδT細胞 / サイトカインレセプター Less

消化管上皮の発生・分化原理の理解に基づく化生発症メカニズムの解明
- Principal Investigator
  
  森健太郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kanazawa Medical University
Molecular mechanisms of region-specific cellular differentiation in the gastrointestinal epithelium.
- Principal Investigator
  
  MORI Kentaro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kanazawa Medical University
Regulatory mechanisms of activated B cell fate which contribute diversity of immune response
- Principal Investigator
  
  Sugai Manabu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Fukui
異所性上皮組織の形成と腫瘍化の分子基盤
- Principal Investigator
  
  横田義史
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Fukui
Functional analysis of newly identified inducible regulatory T cells in immunological reaction and tolerance
- Principal Investigator
  
  Sugai Manabu
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Fukui
  Kyoto University
Molecular basis for the Id2-dependent growth and differentiation controls of gastrointestinal epithelial cells.
- Principal Investigator
  
  YOKOTA Yoshifumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Fukui
Changes in activity of the transcriptional regulator Id by toxic trace elements and redox signaling.Principal Investigator
- Principal Investigator
  
  KUROOKA Hisanori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  University of Fukui
がんタンパク質Idの細胞内局在制御Principal Investigator
- Principal Investigator
  
  黒岡尚徳
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Fukui
Molecular functions of HLH protein Id2 in controlling cell differentiation and proliferation
- Principal Investigator
  
  YOKOTA Yoshifumi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Fukui
Role of a multifunctional protein Id2 in the control of cellular differentiation and function
- Principal Investigator
  
  YOKOTA Yoshifumi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Fukui
  福井医科大学
In vivo analysis of mechanisms underlying cellular differentiation and proliferation control
- Principal Investigator
  
  YOKOTA Yoshmurn
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Fukui
  福井医科大学
Notch/RBP-J複合体による転写活性化におけるヒストンアセチル化の役割Principal Investigator
- Principal Investigator
  
  黒岡尚徳
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Kyoto University
Induction mechanism of V-J recombination by signaling molecules of the IL-7 receptor
- Principal Investigator
  
  IKUTA Koichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  KYOTO UNIVERSITY
Notch細胞質領域のリガンド依存的な切断部位の特定、及びプロテアーゼの同定Principal Investigator
- Principal Investigator
  
  黒岡尚徳
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University

All 2022 2019 2018 2013 2012 2011 2010 2009 2008 2005

All Journal Article Presentation

[Journal Article] Gene expression profile data of the developing small intestine of Id2-deficient mice2019
- Author(s)
  Mori K, Tamada K, Kurooka H, Matsui M, Takumi T, Yokota Y
- Journal Title
  
  Data Brief
  
  Volume: 24 Pages: 103717-103717
- DOI
  10.1016/j.dib.2019.103717
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06316, KAKENHI-PROJECT-19K08452
[Journal Article] Publication Preview Source Id2 Determines Intestinal Identity through Repression of the Foregut Transcription Factor Irx52018
- Author(s)
  Mori, K, Nakamura, H, Kurooka, H, Miyachi, H, Tamada, K, Sugai, M,Takumi, T, Yokota, Y
- Journal Title
  
  Mol Cell Biol
  
  Volume: 38 Issue: 9
- DOI
  10.1128/mcb.00250-17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15232, KAKENHI-PROJECT-16H05138, KAKENHI-PROJECT-16H06316, KAKENHI-PLANNED-16H06463
[Journal Article] The metalloid arsenite induces nuclear export of Id3 possibly via binding to the N-terminal cysteine residues2013
- Author(s)
  Kurooka, H., Sugai, M., Mori, K. and Yokota, Y.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 433 Issue: 4 Pages: 579-585
- DOI
  10.1016/j.bbrc.2013.03.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390073, KAKENHI-PROJECT-24390077, KAKENHI-PROJECT-24659148, KAKENHI-PROJECT-24790194
[Journal Article] BMP signaling is responsible for serum-induced Id2 expression2012
- Author(s)
  Kurooka, H., et al
- Journal Title
  
  Biochem.Biophys.Res.Com.
  
  Volume: 420 Issue: 2 Pages: 281-287
- DOI
  10.1016/j.bbrc.2012.02.150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390092, KAKENHI-PROJECT-24790194
[Journal Article] Glutathione S-transferase M1 inhibits dexamethasone-induced apoptosis in association with the suppression of Bim through dual mechanisms in a lymphoblastic leukemia cell line.2010
- Author(s)
  Hosono, N., Kishi, S., Iho, S., Urasaki, Y., Yoshida, A., Kurooka, H., Yokota, Y., Ueda, T.
- Journal Title
  
  Cancer Sci. 第101巻
  
  Pages: 767-773
- NAID
  10026589943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570128
[Journal Article] Identification of BMP responsive elements in the mouse Id2 gene2010
- Author(s)
  Nakahiro, T., Kurooka, H., Mori, K., Sano, K. and Yokota, Y
- Journal Title
  
  Biochem. Biophys. Res. Com.
  
  Volume: 399 Issue: 3 Pages: 416-421
- DOI
  10.1016/j.bbrc.2010.07.090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390092
[Journal Article] Glutathione S-transferase M1 inhibits dexamethasone-induced apoptosis in association with the suppression of Bim through dual mechanisms in a lymphoblastic leukemia cell line2010
- Author(s)
  Hosono, N., Kishi, S., Iho, S., Urasaki, Y., Yoshida, A., Kurooka, H., Yokota, Y. and Ueda, T
- Journal Title
  
  Cancer Sci.
  
  Volume: 101 Issue: 3 Pages: 767-773
- DOI
  10.1111/j.1349-7006.2009.01432.x
- NAID
  10026589943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390092
[Journal Article] Identification of BMP-responsive elements in the mouse Id2 gene.2010
- Author(s)
  Nakahiro, T., Kurooka, H., Mori, K., Sano, K., Yokota, Y.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 第399巻
  
  Pages: 416-421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570128
[Journal Article] Nucleo-cytoplasmic shuttling of Id2, a negative regulator of basic helix-loop-helix transcription factors.2005
- Author(s)
  Kurooka, H., Yokota, Y.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 4313-4320
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390102
[Journal Article] Nucleo-cytoplasmic shuttling of Id2, a negative regulator of basic helix-loop-helix transcription factors.2005
- Author(s)
  Kurooka H., Yokota Y.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 4313-4320
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390102
[Journal Article] Nucleo-cytoplasmic shuttling of Id2, a negative regulator of basic helix-loop-helix transcription factors.2005
- Author(s)
  Kurooka H., Yokota Y.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 4313-4320
- Data Source
  KAKENHI-PROJECT-14033217
[Journal Article] Nucleo-cytoplasmic shuttling of Id2, a negative regulator of basic helix-loop-helix transcription factors.2005
- Author(s)
  Kurooka, H., Yokota, Y.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 4313-4320
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14033217
[Journal Article] Nucleo-cytoplasmic shuttling of Id2, a negative regulator of basic helix-loop-helix transcription factors.2005
- Author(s)
  Kurooka, H., Yokota, Y.
- Journal Title
  
  J. Bid. Chem. 280
  
  Pages: 4313-4320
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14033217
[Presentation] 転写調節因子Id2によるマウス盲腸形成メカニズム2022
- Author(s)
  森健太郎, 黒岡尚徳, 朝比奈正人
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K08043
[Presentation] 血清が誘導するld2の発現と筋芽細胞の分化阻害におけるBMPシグナルの役割.2012
- Author(s)
  黒岡尚徳、他
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-24390077
[Presentation] Lineage specification of gastrointestinal cells by helix-loop-helix transcription factor Id22011
- Author(s)
  Mori, K., Nakamura, H., Kurooka, H., Tamada, K., Takumi, T. and Yokota, Y.
- Organizer
  第44回日本発生生物学会年会
- Place of Presentation
  沖縄県宜野湾市
- Data Source
  KAKENHI-PROJECT-21390092
[Presentation] 酸化ストレスにより形成されるHLHタンパク質の分子間ジスルフィド結合2010
- Author(s)
  黒岡尚徳
- Organizer
  第33回日本分子生物学会年会/第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-20570128
[Presentation] 酸化ストレスにより形成されるHLH タンパク質の分子間ジスルフィド結合2010
- Author(s)
  黒岡尚徳、横田義史
- Organizer
  第33回日本分子生物学会年会/第83 回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21390092
[Presentation] 酸化ストレスにより形成されるHLHタンパク質の分子間ジスルフィド結合2010
- Author(s)
  黒岡尚徳、横田義史
- Organizer
  第31回日本分子生物学会年会/第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21390092
[Presentation] 酸化ストレスにより形成されるHLHタンパク質の分子間ジスルフィド結合2010
- Author(s)
  黒岡尚徳、横田義史
- Organizer
  第33回日本分子生物学会年会/第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-20570128
[Presentation] BMPシグナルによる転写調節因子Id2の遺伝子発現制御機構2009
- Author(s)
  中廣剛士、黒岡尚徳、佐野和生、横田義史
- Organizer
  日本生化学会北陸支部第27回大会
- Place of Presentation
  福井
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-20570128
[Presentation] BMPシグナルによる転写調節因子Id2の遺伝子発現機構の解析2008
- Author(s)
  中廣剛士、黒岡尚徳、佐野和生、横田義史
- Organizer
  第31回日本分子生物学会年会/第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20570128

1. MORI Kentaro (50397296)

# of Collaborated Projects: 7 results

# of Collaborated Products: 4 results
2. YOKOTA Yoshifumi (50222386)

# of Collaborated Projects: 5 results

# of Collaborated Products: 10 results
3. SUGAI Manabu (90303891)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. BIYAJIMA Kyoko (30552020)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 中村ハルミ (80164325)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. IKUTA Koichi (90193177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TANIGUCHI Yoshihito (00324616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KINOSHITA Kazuo (50293874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KARAYA Kazuhiro (70233997)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 本庶佑 (80090504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 森誠一 (10334814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 木元久 (70283166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 林達成 (80781111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 南部由希子 (70580380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 久木田洋児 (60372744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MATSUI Yukie

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SAKAMOTO hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 内匠透

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KUROOKA Hisanori 黒岡 尚徳

黒岡 尚徳 クロオカ ヒサノリ

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Changes in activity of the transcriptional regulator Id by toxic trace elements and redox signaling.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

がんタンパク質Idの細胞内局在制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Notch/RBP-J複合体による転写活性化におけるヒストンアセチル化の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Notch細胞質領域のリガンド依存的な切断部位の特定、及びプロテアーゼの同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] Gene expression profile data of the developing small intestine of Id2-deficient mice2019

Author(s)

KUROOKA Hisanori 黒岡尚徳

黒岡尚徳クロオカヒサノリ