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Michigami Toshimi  道上 敏美

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MICHIGAMI Toshimi  道上 敏美

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Researcher Number 00301804
Other IDs
Affiliation (Current) 2025: 地方独立行政法人大阪府立病院機構大阪母子医療センター(研究所), 研究所, 所長
2025: 地方独立行政法人大阪府立病院機構大阪母子医療センター(研究所), 骨発育疾患研究部門, 部長
Affiliation (based on the past Project Information) *help 2025: 地方独立行政法人大阪府立病院機構大阪母子医療センター(研究所), 骨発育疾患研究部門, 部長
2020 – 2023: 地方独立行政法人大阪府立病院機構大阪母子医療センター(研究所), 骨発育疾患研究部門, 部長
2019 – 2020: 地方独立行政法人大阪府立病院機構大阪母子医療センター(研究所), 骨発育疾患研究部門(旧環境影響部門), 部長
2019: 地方独立行政法人大阪府立病院機構大阪母子医療センター(研究所), 骨発育疾患研究部門(旧 環境影響部門), 部長
2017 – 2019: 地方独立行政法人大阪府立病院機構大阪母子医療センター(研究所), 環境影響部門, 部長 … More
2017: 地方独立行政法人大阪府立病院機構, 大阪母子医療センター(研究所)・環境影響部門, 部長
2015 – 2016: 地方独立行政法人大阪府立病院機構大阪府立母子保健総合医療センター(研究所), 環境影響部門, 部長
2014: 大阪府立母子保健総合医療センター(研究所), 部長
2013 – 2014: 地方独立行政法人大阪府立病院機構大阪府立母子保健総合医療センター(研究所), その他部局等, その他
2013: 地方独立行政法人大阪府立病院機構大阪府立母子保健総合医療センター(研究所), 環境影響部門, 部長
2012: 地方独立行政法人大阪府立病院機構大阪府立母子保健総合医療センター(研究所), その他部局等, 研究員
2012: 地方独立行政法人大阪府立病院機構大阪府立母子保健総合医療センター研究所, 環境影響部門, 部長
2010 – 2011: Research Institute, Osaka Medical Center for Maternal and Child Health, 環境影響部門, 部長
2010: 大阪府立母子保健総合医療センター研究所, 環境影響部門, 部長
2009: Research Institute, Osaka Medical Center for Maternal and Child Health, 環境影響部門, 部長
2005 – 2008: Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka Hospital Organization, Department of Environmental Medicine, Chief, 環境影響部門, 部長
2007: Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka Prefectural Hospital Oganizationn, Depatment of Environment Medicine, Director
2005 – 2006: 大阪府立母子保険総合医療センター研究所, 環境影響部門, 部長
2003 – 2004: Osaka Medical Center and Research Institute for Maternal and Child Health, Department of Environmental Medicine, Chief, 環境影響部門, 部長
2002: Osaka Medical Center and Research Institute, Department of Environmental Medicine, Section Chief, 環境影響部門, 主任研究員
1998 – 2002: 大阪府立母子保健総合医療センター研究所, 環境影響部門, 主任研究員 Less
Review Section/Research Field
Principal Investigator
Kidney internal medicine / Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics / Embryonic/Neonatal medicine
Except Principal Investigator
Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related / Kidney internal medicine / Orthopaedic surgery / 内分泌・代謝学
Keywords
Principal Investigator
FGF23 / 骨細胞 / リン代謝 / osteoprotegerin / RANKL / リン / 骨芽細胞 / klotho / Na^+ / phosphate … More / megalin / Pi共輸送担体 / リン酸 / メガリン / ビタミンD / PHEX / ナトリウム・リン酸共輸送担体 / Klotho / 無機リン酸 / 破骨細胞 / 神経芽細胞腫 / iPS細胞 / X連鎖性低リン血症性くる病 / 骨成熟 / 骨芽細胞分化 / 胎仔 / リン輸送 / 胎盤 / リン感知 / 胎児 / リン恒常性 / Pi co-transporter / megain / FGF-23 / リン酸再吸収 / 2 / ERK1 / vitamin D / receptor associated protein (RAP) / phosphate co-transporter / sodium / reabsorption / endocytosis / Na / 再吸収 / RAP / エンドサイトーシス / gene therapy / bone metastasis / neuroblastoma / 筋肉内遺伝子導入 / 遺伝子治療 / 骨転移 / FAM20C / DMP1 / Klnotho / リン酸共輸送担体 / ナトリウム / シグナル伝達 / ヌードマウス / 1.25(OH)_2D / 1位水酸化酵素 / 25位水酸化酵素 / 25OHD / 1,25(OH)_2D / 1α位水酸化酵素 / ヌードラット / PTHrP … More
Except Principal Investigator
骨系統疾患 / 骨折 / 骨形成不全症 / 骨芽細胞 / SHP-2 / transgenic mouse / vitamin D / ビタミンD / メガリン / 成長軟骨 / 成長障害 / ビタミンD受容体 / くる病 / 骨疾患 / 代謝性骨疾患 / 骨形成 / FGF23 / リン代謝 / 遺伝子発現 / 低リン血症性くる病 / 骨細胞 / 薬剤開発 / 遺伝子診断 / モデルマウス / iPS細胞 / 成長軟骨帯 / 成長 / 骨石灰化 / ノックインマウス / 脆弱性骨折 / 疾患特異的iPS細胞 / 骨脆弱性 / Pit-2 / Pit-1 / リン / 小児科学 / 小児骨代謝学 / 小児内分泌学 / 小児内分泌学 小児骨代謝学 / 小児科学、小児骨代謝学 / regenerative medicine / molecular biology / gene regulation / collagen / osteoblast / 再生医学 / 分子生物学 / 発現制御 / コラーゲン / LEOPARD syndrome / Noonan syndrome / growth retardation / growth plate / chondrocyte / LEOPARD症候群 / Noonan症候群 / GST-fusion protein / receptor-associated protein / megalin / receptor-associated protein(RAP) / GST融合蛋白 / receptor-associated protein (RAP) / kidney organ culture / renal tubules / transcription activation / promoter / 1 alpha-hydroxylase / digoxigenin / forskolin / 転写活性 / プロモーター / 胎仔 / 2重染色 / in situ hybridization / 腎尿細管 / 腎器官培養 / 1α位水酸化酵素 / 骨粗鬆症 / 創薬 / cGMP / C型Na利尿ペプチド / 栄養学 / HNF4α / 肝発生・分化 / アミノ酸トランスポーター / 肝細胞 / レポーター / 副甲状腺ホルモン / 24位水酸化酵素 / 遺伝子クローニング / ビタミンD代謝 / 遺伝子発現抑制 / 1位水酸化酵素 / 遺伝子プロモーター / ビタミンD応答配列 Less
  • Research Projects

    (22 results)
  • Research Products

    (131 results)
  • Co-Researchers

    (20 People)
  •  遺伝性低リン血症性くる病における異所性骨化発症機序の解明と予防戦略Principal Investigator

    • Principal Investigator
      道上 敏美
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Osama Woman's and Children's Hospital
  •  Novel Molecular Mechanism for Hereditary HypophosphatemiaPrincipal Investigator

    • Principal Investigator
      道上 敏美
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Osama Woman's and Children's Hospital
  •  Analysis of dysfunction of osteocytes to reveal the targets of treatment in genetical bone diseases

    • Principal Investigator
      Ozono Keiichi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Osaka University
  •  Role of Osteocytes in Phosphate Sensing and Its Relation to Skeletal MaturationPrincipal Investigator

    • Principal Investigator
      Michigami Toshimi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Osama Woman's and Children's Hospital
  •  Analysis of mechanism of bone fragility and effects of drugs in osteogenesis imperfecta using a graft model for enchondral bone formation

    • Principal Investigator
      Ozono Keiichi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Osaka University
  •  Local phosphorus production system in bone mineralization: role of alkaline phosphatase

    • Principal Investigator
      Kubota Takuo
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka University
  •  Mechanism for phosphate homeostasis in fetusPrincipal Investigator

    • Principal Investigator
      MICHIGAMI TOSHIMI
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Osama Woman's and Children's Hospital
  •  Phosphate sensing and expression mechanism of genes responsible for hypophosphatemic rickets in osteocytes: Involvement of Pit1

    • Principal Investigator
      Yamazaki Miwa
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Osama Woman's and Children's Hospital
  •  Ozono Keiichi

    • Principal Investigator
      OZONO Keiichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka University
  •  Molecular Mechanism for Phosphate Sensing and Bone-Kidney Functional InteractionPrincipal Investigator

    • Principal Investigator
      MICHIGAMI Toshimi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  Mechanism Underlying the Responsiveness to the Extracellular Phosphate and the Factors which Influence the Sensitivity to FGF23Principal Investigator

    • Principal Investigator
      MICHIGAMI Toshimi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  Hepatocyte nuclear factor 4α promotes protein synthesis through the sodium-coupled neutral amino acid transporter 4 in liver development

    • Principal Investigator
      KONDOU Hiroki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  Functional Relationship between the Molecules Involved in the Renal Phosphate ReabsorptionPrincipal Investigator

    • Principal Investigator
      MICHIGAMI Toshimi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  Regulatory mechanism of the type XI collagen expression in osteoblasts

    • Principal Investigator
      MATSUI Yoshito
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  Mechanisms of Growth Plate Regulation by Protein Tyrosine Phosphatase SHP-2

    • Principal Investigator
      NAMBA Noriyuki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka University
  •  Molecular Mechanisms Underlying the Reabsorption of Inorganic Phosphate in Renal TubulesPrincipal Investigator

    • Principal Investigator
      MICHIGAMI Toshimi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka Hospital Organization
  •  Development of Organ-specific Treatment for Bone Metastasis in NeuroblastomaPrincipal Investigator

    • Principal Investigator
      MICHIGAMI Toshimi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka Medical Center and Research Institute for Maternal and Child Health
  •  Functional analysis of megalin, a key molecule of reabsorption in renal tubular cells ; making and using RAP-transgenic mice

    • Principal Investigator
      OZONO Keiichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Osaka University
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  動物モデルを用いた神経芽細胞腫骨転移メカニズムの解析Principal Investigator

    • Principal Investigator
      道上 敏美
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Pediatrics
    • Research Institution
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  Characterization of the expression of 1 alpha-hydroxylase in kidney and application to renal failure

    • Principal Investigator
      OZONO Keiichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  PTHrP産生腫瘍におけるビタミンD代謝異常および骨軟化症の病態解析-担癌ラットモデルを用いてPrincipal Investigator

    • Principal Investigator
      道上 敏美
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Pediatrics
    • Research Institution
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  ビタミンD応答配列(VDRE)の解析 positive vs negative VDRE

    • Principal Investigator
      OZONO Keiichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Research Institute, Osaka Medical Center for Maternal and Child Health

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation

  • [Journal Article] Complex intrinsic abnormalities in osteoblast lineage cells of X-linked hypophosphatemia: Analysis of human iPS cell models generated by CRISPR/Cas9-mediated gene ablation2024

    • Author(s)
      Nakanishi Tatsuro、Yamazaki Miwa、Tachikawa Kanako、Ueta Ayu、Kawai Masanobu、Ozono Keiichi、Michigami Toshimi
    • Journal Title

      Bone

      Volume: 181 Pages: 117044-117044

    • DOI

      10.1016/j.bone.2024.117044

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07835, KAKENHI-PROJECT-21K07881, KAKENHI-PROJECT-22K07837, KAKENHI-PROJECT-21H02881
  • [Journal Article] Paracrine and endocrine functions of osteocytes2023

    • Author(s)
      Michigami Toshimi
    • Journal Title

      Clinical Pediatric Endocrinology

      Volume: 32 Issue: 1 Pages: 1-10

    • DOI

      10.1297/cpe.2022-0053

    • ISSN
      0918-5739, 1347-7358
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07835
  • [Journal Article] Osteocytes and the pathogenesis of hypophosphatemic rickets2022

    • Author(s)
      Yamazaki Miwa、Michigami Toshimi
    • Journal Title

      Frontiers in Endocrinology

      Volume: 13 Pages: 1005189-1005189

    • DOI

      10.3389/fendo.2022.1005189

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07835, KAKENHI-PROJECT-22K07837
  • [Journal Article] Growth-related skeletal changes and alterations in phosphate metabolism2022

    • Author(s)
      Michigami Toshimi、Tachikawa Kanako、Yamazaki Miwa、Nakanishi Tatsuro、Kawai Masanobu、Ozono Keiichi
    • Journal Title

      Bone

      Volume: 161 Pages: 116430-116430

    • DOI

      10.1016/j.bone.2022.116430

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07835, KAKENHI-PROJECT-21K07881, KAKENHI-PROJECT-22K07837
  • [Journal Article] Roles of osteocytes in phosphate metabolism2022

    • Author(s)
      Michigami Toshimi
    • Journal Title

      Frontiers in Endocrinology

      Volume: 13 Pages: 967774-967774

    • DOI

      10.3389/fendo.2022.967774

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07835
  • [Journal Article] Extracellular Phosphate, Inflammation and Cytotoxicity2022

    • Author(s)
      Michigami Toshimi、Yamazaki Miwa、Razzaque Mohammed S.
    • Journal Title

      Adv Exp Med Biol

      Volume: 1362 Pages: 15-25

    • DOI

      10.1007/978-3-030-91623-7_3

    • ISBN
      9783030916213, 9783030916237
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07835, KAKENHI-PROJECT-22K07837
  • [Journal Article] Advances in understanding of phosphate homeostasis and related disorders2022

    • Author(s)
      Michigami Toshimi
    • Journal Title

      Endocr J

      Volume: 69 Issue: 8 Pages: 881-896

    • DOI

      10.1507/endocrj.EJ22-0239

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07835
  • [Journal Article] Clonal osteoblastic cell lines with CRISPR/Cas9-mediated ablation of Pit1 or Pit2 show enhanced mineralization despite reduced osteogenic gene expression2021

    • Author(s)
      Yamazaki Miwa、Kawai Masanobu、Kinoshita Saori、Tachikawa Kanako、Nakanishi Tatsuro、Ozono Keiichi、Michigami Toshimi
    • Journal Title

      Bone

      Volume: 151 Pages: 116036-116036

    • DOI

      10.1016/j.bone.2021.116036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07835, KAKENHI-PROJECT-21K07881
  • [Journal Article] Lack of PTEN in osteocytes increases circulating phosphate concentrations by decreasing intact fibroblast growth factor 23 levels2020

    • Author(s)
      Masanobu Kawai, Saori Kinoshita, Keiichi Ozono, Toshimi Michigami
    • Journal Title

      Scientific Reports

      Volume: 10(1) Issue: 1 Pages: 21501-21501

    • DOI

      10.1038/s41598-020-78692-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10071, KAKENHI-PROJECT-18K07838
  • [Journal Article] Long-term outcomes for Asian patients with X-linked hypophosphataemia: rationale and design of the SUNFLOWER longitudinal, observational cohort study2020

    • Author(s)
      Kubota Takuo、Fukumoto Seiji、Cheong Hae Il、Michigami Toshimi、Namba Noriyuki、Ito Nobuaki、Tokunaga Shin、Gibbs Yoshimi、Ozono Keiichi
    • Journal Title

      BMJ Open

      Volume: 10 Issue: 6 Pages: e036367-e036367

    • DOI

      10.1136/bmjopen-2019-036367

    • NAID

      120006953549

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08256, KAKENHI-PROJECT-18K07838
  • [Journal Article] Hypophosphatasia in Japan: ALPL Mutation Analysis in 98 Unrelated Patients2020

    • Author(s)
      Michigami T, Tachikawa K, Yamazaki M, Kawai M, Kubota T, Ozono K
    • Journal Title

      Calcif Tissue Int

      Volume: 106 Issue: 3 Pages: 221-231

    • DOI

      10.1007/s00223-019-00626-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10076, KAKENHI-PROJECT-17K10092, KAKENHI-PROJECT-18K07866
  • [Journal Article] Clinical Practice Guidelines for Hypophosphatasia*2020

    • Author(s)
      Michigami Toshimi、Ohata Yasuhisa、Fujiwara Makoto、Mochizuki Hiroshi、Adachi Masanori、Kitaoka Taichi、Kubota Takuo、Sawai Hideaki、Namba Noriyuki、Hasegawa Kosei、Fujiwara Ikuma、Ozono Keiichi
    • Journal Title

      Clinical Pediatric Endocrinology

      Volume: 29 Issue: 1 Pages: 9-24

    • DOI

      10.1297/cpe.29.9

    • NAID

      130007783622

    • ISSN
      0918-5739, 1347-7358
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10076, KAKENHI-PROJECT-18K15708
  • [Journal Article] Japanese nationwide survey of hypophosphatasia reveals prominent differences in genetic and dental findings between odonto and non-odonto types2019

    • Author(s)
      Okawa Rena、Kokomoto Kazuma、Kitaoka Taichi、Kubota Takuo、Watanabe Atsushi、Taketani Takeshi、Michigami Toshimi、Ozono Keiichi、Nakano Kazuhiko
    • Journal Title

      PLOS ONE

      Volume: 14 Issue: 10 Pages: e0222931-e0222931

    • DOI

      10.1371/journal.pone.0222931

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09854, KAKENHI-PROJECT-17K10076
  • [Journal Article] Skeletal mineralization: mechanisms and diseases.2019

    • Author(s)
      Michigami Toshimi
    • Journal Title

      Annals of Pediatric Endocrinology & Metabolism

      Volume: 24 Issue: 4 Pages: 213-219

    • DOI

      10.6065/apem.2019.24.4.213

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07838
  • [Journal Article] Comprehensive genetic analyses using targeted next-generation sequencing and genotype-phenotype correlations in 53 Japanese patients with osteogenesis imperfecta2019

    • Author(s)
      Ohata Y., Takeyari S., Nakano Y., Kitaoka T., Nakayama H., Bizaoui V., Yamamoto K., Miyata K., Yamamoto K., Fujiwara M., Kubota T., Michigami T., Yamamoto K., Yamamoto T., Namba N., Ebina K., Yoshikawa H., Ozono K.
    • Journal Title

      Osteoporosis International

      Volume: 30 Issue: 11 Pages: 2333-2342

    • DOI

      10.1007/s00198-019-05076-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15708, KAKENHI-PROJECT-17K10076, KAKENHI-PROJECT-18H02780
  • [Journal Article] Roles of Phosphate in Skeleton2019

    • Author(s)
      Michigami Toshimi、Ozono Keiichi
    • Journal Title

      Frontiers in Endocrinology

      Volume: 10 Pages: 180-180

    • DOI

      10.3389/fendo.2019.00180

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07838
  • [Journal Article] Phosphate as a Signaling Molecule and Its Sensing Mechanism2018

    • Author(s)
      Toshimi Michigami, Masanobu Kawai, Miwa Yamazaki, Keiichi Ozono
    • Journal Title

      Physiological Reviews

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09635
  • [Journal Article] Phosphate as a Signaling Molecule and Its Sensing Mechanism.2018

    • Author(s)
      Michigami T, Kawai M, Yamazaki M, Ozono K
    • Journal Title

      Physiol Rev

      Volume: 98 Issue: 4 Pages: 2317-2348

    • DOI

      10.1152/physrev.00022.2017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10092, KAKENHI-PROJECT-18K07838, KAKENHI-PROJECT-18K07866
  • [Journal Article] Phosphate as a Signaling Molecule and Its Sensing Mechanism2018

    • Author(s)
      Michigami T, Kawai M, Yamazaki M, Ozono K.
    • Journal Title

      Physiological Reviews

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09736
  • [Journal Article] Extracellular Phosphate Induces the Expression of Dentin Matrix Protein 1 Through the FGF Receptor in Osteoblasts.2017

    • Author(s)
      Nishino J, Yamazaki M, Kawai M et al.
    • Journal Title

      J Cell Biochem.

      Volume: 118 Issue: 5 Pages: 1151-1163

    • DOI

      10.1002/jcb.25742

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461558, KAKENHI-PROJECT-15K09635, KAKENHI-PROJECT-15K09736, KAKENHI-PROJECT-26861717, KAKENHI-PROJECT-17K10092
  • [Journal Article] Inorganic Phosphate Activates the AKT/mTORC1 Pathway and Shortens the Life Span of an α‑Klotho-Deficient Model.2016

    • Author(s)
      Kawai M, Kinoshita S, Ozono K, Michigami T.
    • Journal Title

      Journal of American Society of Nephrology

      Volume: Feb 12, E-pub

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09736
  • [Journal Article] Inorganic Phosphate Activates the AKT/mTORC1 Pathway and Shortens the Life Span of an α Klotho-Deficient Model.2016

    • Author(s)
      Kawai M et al.
    • Journal Title

      J Am Soc Nephrol.

      Volume: 27 Issue: 9 Pages: 2810-2824

    • DOI

      10.1681/asn.2015040446

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461558, KAKENHI-PROJECT-15K09736
  • [Journal Article] Current concepts in perinatal mineral metabolism.2016

    • Author(s)
      Ohata Y, Ozono K, Michigami T.
    • Journal Title

      Clinical Pediatric Endocrinology

      Volume: 25 Pages: 9-17

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K09736
  • [Journal Article] Interleukin-1-induced acute bone resorption facilitates the secretion of fibroblast growth factor 23 into the circulation.2015

    • Author(s)
      Yamazaki M, Kawai M, Miyagawa K, Ohata Y, Tachikawa K, Kinoshita S, Nishino J, Ozono K, Michigami T.
    • Journal Title

      Journal of Bone and Mineral Metabolism

      Volume: 33 Pages: 342-354

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K09736
  • [Journal Article] Overgrowth syndrome associated with a gain-of-functionmutation of the natriuretic   peptide receptor 2 (NPR2) gene.2014

    • Author(s)
      Miura K, Kim OH, Lee HR, Namba N, Michigami T, Yoo WJ, Choi H, Ozono K, Cho TJ.
    • Journal Title

      Am J Med Genet A

      Volume: 164A Issue: 1 Pages: 156-163

    • DOI

      10.1002/ajmg.a.36218

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Journal Article] Sympathetic activation induces skeletal Fgf23 expression in a circadian rhythm-dependent manner.2014

    • Author(s)
      Kawai M, Kinoshita S, Shimba S, Ozono K, Michigami T
    • Journal Title

      J Biol Chem

      Volume: 289 Issue: 3 Pages: 1457-1466

    • DOI

      10.1074/jbc.m113.500850

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590091, KAKENHI-PROJECT-23591227, KAKENHI-PROJECT-23591526
  • [Journal Article] Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of hyp mice2014

    • Author(s)
      Okano T(12), 他13人
    • Journal Title

      J Bone Miner Res

      Volume: 印刷中 Issue: 7 Pages: 0-0

    • DOI

      10.1002/jbmr.2186

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390022, KAKENHI-PROJECT-23591227, KAKENHI-PROJECT-23591526, KAKENHI-PROJECT-23791216, KAKENHI-PROJECT-25282022, KAKENHI-PROJECT-26461558
  • [Journal Article] Interleukin-1-induced acute bone resorption facilitates the secretion of fibroblast growth factor 23 into the circulation.2014

    • Author(s)
      Yamazaki M, Kawai M, Miyagawa K, Ohata Y, Tachikawa K, Kinoshita S, Nishino J, Ozono K, Michigami T.
    • Journal Title

      J Bone Miner Metab.

      Volume: 0 Issue: 3 Pages: 0-0

    • DOI

      10.1007/s00774-014-0598-2

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23791216, KAKENHI-PROJECT-15K09635, KAKENHI-PROJECT-26461558
  • [Journal Article] Dysregulated gene expression in the primary osteoblasts and osteocytes isolated from hypophosphatemic Hyp mice.2014

    • Author(s)
      Miyagawa K, Yamazaki M, Kawai M, Nishino J, Koshimizu T, Ohata Y, Tachikawa K, Mikuni-Takagaki Y, Kogo M, Ozono K, Michigami T
    • Journal Title

      PLoS One

      Volume: 9 Issue: 4 Pages: 0-0

    • DOI

      10.1371/journal.pone.0093840

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591227, KAKENHI-PROJECT-23591526, KAKENHI-PROJECT-23791216, KAKENHI-PROJECT-25350542, KAKENHI-PROJECT-26461558, KAKENHI-PROJECT-26861717
  • [Journal Article] FGF23 suppresses chondrocyte proliferation in the presence of soluble α-Klotho both in vitro and in vivo.2013

    • Author(s)
      Kawai M, Kinoshita S, Kimoto A, Hasegawa Y, Miyagawa K, Yamazaki M, Ohata Y, Ozono K, Michigami T.
    • Journal Title

      J Biol Chem

      Volume: 288 Issue: 4 Pages: 2414-2427

    • DOI

      10.1074/jbc.m112.410043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591227, KAKENHI-PROJECT-23591526, KAKENHI-PROJECT-23791216, KAKENHI-PROJECT-24390264
  • [Journal Article] Retention of fetuin-A in renal tubular lumen protects the kidney from nephrocalcinosis in rats2013

    • Author(s)
      Matsui I
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 304 Issue: 6 Pages: 751-60

    • DOI

      10.1152/ajprenal.00329.2012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390222, KAKENHI-PROJECT-22590891, KAKENHI-PROJECT-23591227, KAKENHI-PROJECT-23592740, KAKENHI-PROJECT-23592741, KAKENHI-PROJECT-24591237
  • [Journal Article] Regulatory mechanisms for the development of growth plate cartilage2013

    • Author(s)
      Michigami T
    • Journal Title

      Cell Mol Life Sci

      Volume: 70 Issue: 22 Pages: 4213-4221

    • DOI

      10.1007/s00018-013-1346-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Journal Article] Retention of fetuin-A in renal tubular lumen protects the kidney from nephrocalcinosis in rats.2013

    • Author(s)
      Matsui I, Hamano T, Mikami S, Inoue K, Shimomura A, Nagasawa Y, Michigami T, et al.
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Journal Article] Extracellular phosphate as a signaling molecule2013

    • Author(s)
      Michigami T
    • Journal Title

      Contrib Nephrol

      Volume: 180 Pages: 14-24

    • DOI

      10.1159/000346776

    • ISBN
      9783318023695, 9783318023701
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Journal Article] Role of megalin and the soluble form of its ligand RAP in Cd-metallothionein endocytosis and Cd-metallothionein-induced nephrotoxicity in vivo.2012

    • Author(s)
      Onodera A, Tani M, Michigami T, Yamagata M, Min KS, Tanaka K, Nakanishi T, Kimura T, Itoh N.
    • Journal Title

      Toxicol Lett

      Volume: 212 Pages: 91-96

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Journal Article] An overgrowth disorder associated with excessive production of cGMP due to a gain-of-function mutation of the natriuretic peptide receptor 2 gene.2012

    • Author(s)
      Miura K, Namba N, Fujiwara M, Ohata Y, Ishida H, Kitaoka T, Kubota T, Hirai H, Higuchi C, Tsumaki N, Yoshikawa H, Sakai N, Michigami T, Ozono K.
    • Journal Title

      PLoS One

      Volume: 7 Issue: 8 Pages: e42180-e42180

    • DOI

      10.1371/journal.pone.0042180

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591227, KAKENHI-PROJECT-24390264, KAKENHI-PROJECT-24390354
  • [Journal Article] Vinculin functions as regulator of chondrogenesis.2012

    • Author(s)
      Koshimizu T, Kawai M, Kondou H, Tachikawa K, Sakai N, Ozono K, Michigami T.
    • Journal Title

      J Biol Chem

      Volume: 287 Issue: 19 Pages: 15760-15775

    • DOI

      10.1074/jbc.m111.308072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591227, KAKENHI-PROJECT-23591526, KAKENHI-PROJECT-23591566, KAKENHI-PROJECT-24390264
  • [Journal Article] Circulating Levels of Soluble α-Klotho Are Markedly Elevated in Human Umbilical Cord Blood2011

    • Author(s)
      Ohata Y
    • Journal Title

      J Clin Endocrinol Metab

      Volume: 96(6) Issue: 6 Pages: E943-E947

    • DOI

      10.1210/jc.2010-2357

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591319, KAKENHI-PROJECT-23591227
  • [Journal Article] Cellular ATP synthesis mediated by type III sodium-dependent phosphate transporter Pit-1 is critical to chondrogenesis.2011

    • Author(s)
      Sugita A, Kawai S, Hayashibara T, Amano A, Ooshima T, Michigami T, Yoshikawa H, Yoneda T.
    • Journal Title

      J Biol Chem 286

      Pages: 3094-3103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Journal Article] Both FGF23 and extracellular phosphate activate Raf/MEK/ERK pathway via FGF receptors in HEK293 cells.2010

    • Author(s)
      Yamazaki M, Ozono K, Okada T, Tachikawa K, Kondou H, Ohata Y, Michigami T.
    • Journal Title

      J Cell Biochem 111

      Pages: 1210-1221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Journal Article] Clinical characteristics of perinatal lethal hypophosphatasia : a report of 6 cases.2010

    • Author(s)
      Nakamura-Utsunomiya A, Okada S, Hara K, Miyagawa S, Takeda K, Fukuhara R, Nakata Y, Hayashidani M, Tachikawa K, Michigami T, Ozono K, Kobayashi M
    • Journal Title

      Clin Pediatr Endocrinol 19

      Pages: 7-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Journal Article] Signaling of extracellular inorganic phosphate up-regulates cyclin D1 expression in proliferating chondrocytes via the Na^+/Pi cotransporter Pit-1 and Raf/MEK/ERK pathway.2010

    • Author(s)
      Kimata M, Michigami T, Tachikawa K, Okada T, Koshimizu T, Yamazaki M, Kogo M, Ozono K.
    • Journal Title

      Bone 47

      Pages: 938-947

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Journal Article] Severe arterial hypertension : a possible complication of McCune-Albright syndrome.2009

    • Author(s)
      Ohata Y, Yamamoto T, Mori I, Kikuchi T, Michigami T, Imanishi Y, Satomura K, Ida S, Ozono K.
    • Journal Title

      Eur J Pediatr 168

      Pages: 871-876

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Journal Article] Oncogenic nucleoporin CAN/Nup214 interacts with vitamin D receptor and modulates its function.2009

    • Author(s)
      Miyauchi Y, Sakaguchi N, Okada T, Makishima M, Ozono K, Michigami T.
    • Journal Title

      J Cell Biochem 106

      Pages: 1090-1101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Journal Article] Czech dysplasia occurring in a Japanese family.2009

    • Author(s)
      Matsui Y, Michigami T, Tachikawa K, Yamazaki M, Kawabata H, Nishimura G.
    • Journal Title

      Am J Med Genet A 49A

      Pages: 2285-2289

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Journal Article] Clinical usefulness2008

    • Author(s)
      Endo I, Fukumoto S, Ozono K, Namba N, Tanaka H, Inoue D, Minagawa M, Sugunoto T, Yamauchi M, Michigami T, Matsumoto T.
    • Journal Title

      Bone 42

      Pages: 1235-1239

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590921
  • [Journal Article] Causes and differential diagnosis of hypocalcemia-recommendation proposed by expert panel supporeted by Ministry of Health, Labour and Welfare, Japan.2008

    • Author(s)
      Fukumoto S, Namba N, Ozono K, Yamauchi M, Sugimoto T, Michigami T, Tanaka H, Inoue D, Minagawa M, Endo I, Matsumoto T.
    • Journal Title

      Endocr J 55

      Pages: 784-794

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Journal Article] Clinical usefulness of measurement of fibroblast growth factor 23 (FGF23) in hypophosphatemic patients. Proposal of diagnostic criteria using FGF23 measurement.2008

    • Author(s)
      Endo I, Fukumoto S, Ozono K, Namba N, Tanaka H, Inoue D, Minagawa M, Sugimoto T, Yamauchi M, Michigami T, Matsumoto T.
    • Journal Title

      Bone 42

      Pages: 1235-1239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Journal Article] PTH/cAMP/PKA signaling facilitates canonical Wnt signaling via inactivation of glycogen synthase kinase-3β in osteoblastic Saos-2 cells.2008

    • Author(s)
      Suzuki A, Ozono K, Kubota T, Kondou H, Tachikawa K, Michigami T.
    • Journal Title

      J Cell Biochem 104

      Pages: 314-317

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590921
  • [Journal Article] An Lrp6 hypomorphic mutation affects bone mass through bone resorption in mice and impairs interaction with Mesd.2008

    • Author(s)
      Kubota T, Michigami T, Sakaguchi N, Kokubu C, Suzuki A, Namba N, Sakai N, Nakajima S, Imai K, Ozono K.
    • Journal Title

      J Bone Miner Res 23

      Pages: 1661-1671

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Journal Article] PTH/cAMP/PKA signaling facilitates canonical Wnt signaling via inactivation of glycogen synthase kinase-3β in osteoblastic Saos-2 cells.2008

    • Author(s)
      Suzuki A, Ozono K, Kubota T, Kondou H, Tachikawa K, Michigami T.
    • Journal Title

      J Cell Biochem 104

      Pages: 314-317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Journal Article] Involvement of nuclear factor I transcription/replication factor in the early stage of chondrocytac differentiation.2007

    • Author(s)
      Uchihashi T, Kimata M, Tachikawa K, Koshimizu T, Okada T, Ihara-Watanabe M, Sakai N, Kogo M, Ozono K, Michigami T.
    • Journal Title

      Bone 41

      Pages: 1025-1035

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590921
  • [Journal Article] Hereditary hypophosphatemic rickets with hypercalciuria a study for the phosphate transporter gene IIc and osteoblastic function.2007

    • Author(s)
      Yamamoto T, Michigami T. Aranami F, Segawa H, Yoh K, Nakajima S, Miyamoto KI, Ozono K.
    • Journal Title

      J Bone Miner Metab 25

      Pages: 407-413

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590921
  • [Journal Article] Lack of puberty despite elevated estradiol in a 46, XY phenotypic female with Frasier syndrome.2006

    • Author(s)
      Miyoshi Y, Santo Y, Tachikawa K, Namba N, Hirai H, Mushiake S, Nakajima S, Michigami T, Ozono K
    • Journal Title

      Endocrine Journal 53・3

      Pages: 371-376

    • Data Source
      KAKENHI-PROJECT-18590921
  • [Journal Article] G-protein stimulatory a subunit is involved in osteogenic activity in osteoblastic cell line SaOS-2 cells.2006

    • Author(s)
      Yamazaki M, Suzuki A, Ozono K, Michigami T.
    • Journal Title

      Clinical Pediatric Endocrinology 15・2

      Pages: 65-72

    • Data Source
      KAKENHI-PROJECT-18590921
  • [Journal Article] Lack of puberty despite elevated estradiol in a 46,XY phenotypic female with Frasier syndrome.2006

    • Author(s)
      Miyoshi Y, Santo Y, Tachikawa K, Namba N, Hirai H, Mushiake S, Nakajima S, Michigami T, Ozono K
    • Journal Title

      Endocr J 53(3)

      Pages: 371-376

    • NAID

      10018178097

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591086
  • [Journal Article] Molecular bases of diseases characterized by hypophosphatemia and phosphaturia : new understanding.2006

    • Author(s)
      Ozono K, Michigami T, Namba N, Nakajima S, Yamamoto T.
    • Journal Title

      Clinical Pediatric Endocrinology 15・4

      Pages: 129-135

    • Data Source
      KAKENHI-PROJECT-18590921
  • [Journal Article] Molecular bases of diseases characterized by hypophosphatemia and phosphaturia : New understanding2006

    • Author(s)
      Ozono K, Michigami T, Namba N, Nakajima S, Yamamoto T
    • Journal Title

      Clin Pediatr Endocrinol 15(4)

      Pages: 129-135

    • NAID

      130004430991

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591086
  • [Journal Article] Molecular bases of diseases characterized by hypophosphatemia and phosphaturia : New understanding.2006

    • Author(s)
      Ozono K, Michigami T, Namba N, Nakajima S, Yamamoto T
    • Journal Title

      Clin Pediatr Endocrinol 15(4)

      Pages: 129-135

    • NAID

      130004430991

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591086
  • [Journal Article] The Sp1 family of transcription factors regulates the human alpha 2 (XI) collagen gene (COL11A2) in Saos-2 osteoblastic cells.2006

    • Author(s)
      Goto T, Matsui Y, Fernandes RJ, Hanson DA, Kubo T, Yutaka K, Michigami T, Komori T, Fujita T, Yang L, Eyre DR, Yasui N.
    • Journal Title

      Journal of Bone and Miner Research 21・5

      Pages: 661-673

    • Data Source
      KAKENHI-PROJECT-18590921
  • [Journal Article] Intraperitoneal administration of recombinant receptor-associated protein cause phosphaturia via an alteration in subcellular distribution of the renal sodium phosphate co-transporter.2005

    • Author(s)
      Yamagata M, Ozono K, Hashimoto Y, Miyauchi Y, Kondou H, Michigami T.
    • Journal Title

      Journal of American Society of Nephrology 16・8

      Pages: 2338-2345

    • Data Source
      KAKENHI-PROJECT-16590809
  • [Journal Article] Importin 4 is responsible for ligand-independent nuclear translocation of vitamin D receptor.2005

    • Author(s)
      Miyauchi Y, Michigami T, Sakaguchi N, Sekimoto T, Yoneda T, Pike JW, Yamagata M, Ozono K.
    • Journal Title

      Journal of Biological Chemistry 280・49

      Pages: 40901-40908

    • Data Source
      KAKENHI-PROJECT-16590809
  • [Journal Article] Intraperitoneal administration of recombinant receptor-associated protein causes phosphaturia via an alteration in subcellular distribution of the renal sodium2005

    • Author(s)
      Yamagata M, Ozono K, Hashimoto Y, Miyauchi Y, Kondou H, Michigami T
    • Journal Title

      Journal of American Society of Nephrology 16・8

      Pages: 2338-2345

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590809
  • [Journal Article] Intraperitoneal administration of recombinant receptor-associated protein causes phosphaturia via an alteration in subcellular distribution of the renal sodium phosphate co-transporter.2005

    • Author(s)
      Yamagata M, Ozono K, Hashimoto Y, Miyauchi Y, Kondou H, Michigami T.
    • Journal Title

      J Am Soc Nephrol 16

      Pages: 2338-2345

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590809
  • [Journal Article] Examination of megalin in renal tubular epithelium from patients with Dent disease.2004

    • Author(s)
      Santo Y, Hirai H, Shima M, Yamagata M, Michigami T, Nakajima S, Ozono K.
    • Journal Title

      Pediatric Nephrology 19・6

      Pages: 612-615

    • Data Source
      KAKENHI-PROJECT-16590809
  • [Journal Article] Examination of megalin in renal tubular epithelium from patients with Dent disease.2004

    • Author(s)
      Santo Y, Hirai H, Shima M, Yamagata M, Michigami T, Nakajima S, Ozono K.
    • Journal Title

      Pediatr Nephrol 19

      Pages: 612-615

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590809
  • [Journal Article] In vivo electroporation法によるOstesoprotegerin持続発現を用いた代謝性骨疾患遺伝子治療の有効性の検討2003

    • Author(s)
      道上 敏美
    • Journal Title

      Osteoporosis Japan 11

      Pages: 762-767

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570793
  • [Journal Article] Usefulness of gene therapy using in vivo electroporation with osteoprotegerin expression vector for metabolic bone diseases. (Japanese)2003

    • Author(s)
      Michigami T.
    • Journal Title

      Osteoporosis Japan 11

      Pages: 762-767

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570793
  • [Journal Article] The effect of the bisphosphonate ibandronate on breast cancer metastasis to visceral organs.2002

    • Author(s)
      Michigami T, Hiraga T, Williams PJ, Niewolna M, Nishimura R, Mundy GR, Yoneda T
    • Journal Title

      Breast Cancer Res Treat 75

      Pages: 249-258

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570793
  • [Journal Article] The effect of the bisphosphonate ibandronate on breast cancer2002

    • Author(s)
      Michigami T, Hiraga T, Williams PJ, Niewolna M, Nishimura R, Mundy GR, Yoneda T.
    • Journal Title

      Breast Cancer Res Treat 75

      Pages: 249-258

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570793
  • [Presentation] X連鎖性低リン血症性くる病の骨芽細胞系列における複合的異常:PHEX欠損ヒトiPS細胞モデルを用いた解析2023

    • Author(s)
      中西達郎, 山﨑美和, 立川加奈子, 川井正信, 大薗恵一, 道上敏美
    • Organizer
      第41回日本骨代謝学会学術集会.
    • Data Source
      KAKENHI-PROJECT-21K07835
  • [Presentation] Complex Abnormalities in Osteoblasts/Osteocytes of X-Linked Hypophosphatemia: Analysis of PHEX-Knockout Human iPS Cells Generated by CRISPR/Cas9 Genome Editing.2023

    • Author(s)
      Michigami Toshimi, Nakanishi Tatsuro, Yamazaki Miwa, Tachikawa Kanako, Ueta Ayu, Kawai Masanobu, Ozono Keiichi
    • Organizer
      American Society for Bone and Mineral Research 2023 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07835
  • [Presentation] CRISPR/Cas9によるPHEX欠損ヒトiPS細胞の樹立および解析2022

    • Author(s)
      中西達郎, 山﨑美和, 立川加奈子, 川井正信, 大薗恵一, 道上敏美
    • Organizer
      第40回日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07835
  • [Presentation] 骨細胞による骨・全身性制御2022

    • Author(s)
      道上敏美
    • Organizer
      第95回日本整形外科学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07835
  • [Presentation] 骨芽細胞機能におけるIII型ナトリウム/リン酸共輸送担体の役割2020

    • Author(s)
      山﨑美和, 川井正信, 大薗恵一, 道上敏美.
    • Organizer
      第93回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07838
  • [Presentation] III型ナトリウム/リン酸共輸送担体は骨石灰化およびピロリン酸・ATP代謝を制御する2020

    • Author(s)
      山﨑美和, 川井正信, 木下さおり, 大薗恵一, 道上敏美
    • Organizer
      第22回日本骨粗鬆症学会/第37回日本骨代謝学会学術集会合同集会
    • Data Source
      KAKENHI-PROJECT-18K07838
  • [Presentation] Functional control of osteoblasts by type III sodium/phosphate cotransporters.2019

    • Author(s)
      Yamazaki Miwa, Kawai Masanobu, Ozono Keiichi, Michigami Toshimi
    • Organizer
      42nd Annual meeting of the American Society for Bone and Mineral Research.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07838
  • [Presentation] Mutation analysis of the PHEX gene and genotype-phenotype correlation in 37Japanese patients X-linked hypophosphatemic rickets2019

    • Author(s)
      Ohata Y, Kubota T, Takeyari S, Kitaoaka T, Nakano Y, Miyata K, Yamada C, Ozono K, Ishihara Y, Nakayama H, Yamamoto K, Fujiwara M, Yamamoto K, Michigami T, Mabe H, Yamaguchi T, Matsui K, Tamada I, Namba N, Yamamoto A, Etoh J, Kawaguchi A
    • Organizer
      2019 Annual Meeting of American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10076
  • [Presentation] 日本人低ホスファターゼ症患者52例のベースラインの検討 ―ALP酵素補充療法特定使用成績調査より―2019

    • Author(s)
      窪田拓生, 藤原幾磨, 道上敏美, 渡邉 淳, 難波範行, 鬼頭浩史, 室月 淳, 杉山裕一朗, 仲野和彦, 笹谷晴恵, 長谷川航, 別所友子, 澤井英明, 大薗恵一
    • Organizer
      第53回日本小児内分泌学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10076
  • [Presentation] Skeletal Mineralization: Mechanisms and Diseases.2019

    • Author(s)
      Michigami Toshimi
    • Organizer
      45th Annual Congress of Korean Society of Pediatric Endocrinology
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07838
  • [Presentation] 病態から理解する、くる病と骨軟化症の診断と治療.2019

    • Author(s)
      道上敏美
    • Organizer
      第29回 臨床内分泌代謝Update
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07838
  • [Presentation] 骨格の石灰化機構とその破綻による種々の病態2018

    • Author(s)
      道上敏美
    • Organizer
      第36回内分泌代謝学サマーセミナー
    • Data Source
      KAKENHI-PROJECT-18K07838
  • [Presentation] 低リン血症性くる病と骨軟化症―病態から抗FGF23抗体による新規治療までー2018

    • Author(s)
      道上敏美
    • Organizer
      第28回日本内分泌学会臨床内分泌代謝Update
    • Data Source
      KAKENHI-PROJECT-18K07838
  • [Presentation] X連鎖性低リン血症性くる病に併存するhypovitaminosis Dの検討2018

    • Author(s)
      中山尋文・宮田京・中野由佳子・山本賢一・武鑓真司・大幡泰久・北岡太一・窪田拓生・大薗恵一・道上敏美・山本勝輔
    • Organizer
      第91回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K10076
  • [Presentation] ターゲットエクソーム解析を用いた日本人骨形成不全患者47名の網羅的遺伝子解析と表現型解析2018

    • Author(s)
      大幡泰久,武鑓真司,中野由佳子,山本賢一,中山尋文,北岡太一,窪田拓生,道上敏美,山本威久,大薗恵一
    • Organizer
      第36回 日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02780
  • [Presentation] Comprehensive Genetic Analysis by Targeted Next Generation Sequencing and Genotype-phenotype Correlation of 47 Japanese Patients with Osteogenesis Imperfecta2018

    • Author(s)
      Ohata Y, Takeyari S, Kitaoka T, Nakayama H, Varoona Bizaoui, Nakano N, Yamamoto K, Miyata K, Yamamoto K, Kubota T, Yamamoto K, Michigami T, Yamamoto T, Ozono K
    • Organizer
      ASBMR2018 Auual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02780
  • [Presentation] ターゲットエクソーム解析を用いた日本人骨形成不全患者52名の網羅的遺伝子解析と 表現型解析2018

    • Author(s)
      大幡泰久,武鑓真司,中野由佳子,山本賢一,宮田 京,中山尋文 Varoona Bizaoui,北岡太一,窪田拓生,山本勝輔,道上敏美,山本威久,大薗恵一
    • Organizer
      第52回 日本小児内分泌学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02780
  • [Presentation] リンの恒常性維持とシグナル分子としてのリン2018

    • Author(s)
      道上敏美
    • Organizer
      第91回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07838
  • [Presentation] Role of type III Sodium/Phosphate Co-transporters in the Responsiveness of Osteoblasts to Extracellular Inorganic Phosphate2017

    • Author(s)
      Toshimi Michigami, Miwa Yamazaki, Masanobu Kawai, Keiichi Ozono
    • Organizer
      8th International Conference on Children’s Bone Health
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09635
  • [Presentation] 骨芽細胞の細胞外無機リン酸応答性におけるⅢ型ナトリウム/リン酸共輸送担体の役割:Pit2欠損細胞を用いた解析2017

    • Author(s)
      山崎美和、川井正信、大薗恵一、道上敏美
    • Organizer
      第35回日本骨代謝学会
    • Data Source
      KAKENHI-PROJECT-15K09635
  • [Presentation] Role of type III sodium/phosphate co-transporters in the responsiveness of osteoblasts to extracellular inorganic phosphate2017

    • Author(s)
      Michigami T, Yamazaki M, Kawai M, Ozono K.
    • Organizer
      8th International Conference on Children’s Bone Health
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09736
  • [Presentation] Hypophosphatemic Rickets: Current Status and Future Perspectives.2016

    • Author(s)
      Michigami T.
    • Organizer
      The 9th Biennial Scientific Meeting of the Asia Pacific Paediatric Endocrine Society/The 50th Annual Meeting of the Japanese Society for Pediatric Endocrinology.
    • Place of Presentation
      東京
    • Year and Date
      2016-11-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09736
  • [Presentation] 骨芽細胞の細胞外無機リン酸惹起シグナル受容におけるPit1の関与:CRISPR/Casシステムを用いた解析.2016

    • Author(s)
      山﨑美和,川井正信,立川加奈子,西野仁,大薗惠一,道上敏美.
    • Organizer
      第34回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-15K09736
  • [Presentation] Signaling of extracellular inorganic phosphate induces the expression of Dmp1 in osteoblast/osteocytes lineage cells via Na^+/Pi Co-transporter and MEK/ERK pathway2013

    • Author(s)
      Nishino J, Miyagawa K, Kawai M, Yamazaki M, Tachikawa K, Mikuni-Takagaki Y, Kogo M, Ozono K, Michigami T
    • Organizer
      35th Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Bartimore
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] 2013. Sympathetic activation induces skeletal Fgf23 expression in a circadian rhythm dependent manner2013

    • Author(s)
      Kawai M, Kinoshita S, Shimba S, Ozono K, Michigami T
    • Organizer
      35th Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Bartimore
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] Sympathetic activation induces skeletal Fgf23 expression in a circadian rhythm dependent manner.2013

    • Author(s)
      Kawai M, Kinoshita S, Shimba S, Ozono K, Michigami T.
    • Organizer
      35th Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Bartimore, USA
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] Fetal stage-specific mineral metabolism in Hyp mice is associated with effects of FGF23 on placenta2013

    • Author(s)
      Ohata Y, Yamazaki M, Kawai M, Tachikawa K, Koinuma T, Miyagawa K, Kimoto A, Nakayama M, Namba N, Yamamoto H, Ozono K, Michigami T
    • Organizer
      35th Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Bartimore
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] Signaling of extracellular inorganic phosphate induces the expression of Dmp1 in osteoblast/osteocytes lineage cells via Na+/Pi Co-transporter and MEK/ERK pathway.2013

    • Author(s)
      Nishino J, Miyagawa K, Kawai M, Yamazaki M, Tachikawa K, Mikuni-Takagaki Y, Kogo M, Ozono K, Michigami T.
    • Organizer
      35th Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Bartimore, USA
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] Fetal stage-specific mineral metabolism in Hyp mice is associated with effects of FGF23 on placenta.2013

    • Author(s)
      Ohata Y, Yamazaki M, Kawai M, Tachikawa K, Koinuma T, Miyagawa K, Kimoto A, Nakayama M, Namba N, Yamamoto H, Ozono K, Michigami T
    • Organizer
      35th Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Bartimore, USA
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] 骨細胞と骨外臓器との連関2012

    • Author(s)
      道上敏美
    • Organizer
      第30回日本骨代謝学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] FGF23は可溶型Klotho存在下で軟骨細胞の増殖・成熟を抑制する2012

    • Author(s)
      川井正信、木下さおり、大幡泰久、宮川和晃、山﨑美和、大薗恵一、道上敏美
    • Organizer
      第30回 日本骨代謝学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] 骨軟化症を合併する抗ミトコンドリア抗体(M2)陽性Fanconi症候群の近位尿細管ではNaPi-2cと共にメガリンの発現も低下する2012

    • Author(s)
      小林郁江,今西康雄,永田友貴,山形雅代,蔵城雅文,石村栄治,道上敏美
    • Organizer
      第30回日本骨代謝学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] FGF23は可溶型klotho存在下で軟骨細胞の増殖・成熟を抑制する2012

    • Author(s)
      川井正信,木下さおり,大幡泰久,宮川和晃,山﨑美和,大薗惠一,道上敏美
    • Organizer
      第30回日本骨代謝学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] Osteoclastic bone resorption might be involved in the secretion of FGF23 into circulation2012

    • Author(s)
      Yamazaki M, Miyagawa K, Ohata Y, Kawai M, Ozono K, Michigami T
    • Organizer
      34th Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Minneapolis
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] FGF23 suppresses chondrocyte proliferation and maturation in the presence of soluble alpha-Klotho both in vitro and in viv.2012

    • Author(s)
      Kawai M, Kinoshita S, Ohata Y, Miragawa K, Yamazaki M, Ozono K, Michigami T.
    • Organizer
      34th Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Minneapolis
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] Osteoclastic bone resorption might be involved in the secretion of FGF23 into circulation.2012

    • Author(s)
      Yamazaki M, MIyagawa K, Ohata Y, Kawai M, Ozono K, Michigami T.
    • Organizer
      34th Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Minneapolis
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] FGF23 suppresses chondrocyte proliferation and maturation in the presence of soluble a-Klotho both in vitro and in vivo2012

    • Author(s)
      Kawai M, Kinoshita S, Ohata Y, Miyagawa K, Yamazaki M, Ozono K, Michigami T
    • Organizer
      34th Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Minneapolis
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] FGF23の血中分泌過程における破骨細胞性骨吸収の関与の可能性2012

    • Author(s)
      山﨑美和、宮川和晃、大幡泰久、川井正信、大薗恵一、道上敏美
    • Organizer
      第30回 日本骨代謝学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] FGF23の血中分泌過程における破骨細胞性骨吸収の関与の可能性2012

    • Author(s)
      山﨑美和,宮川和晃,大幡泰久,川井正信,大薗惠一,道上敏美
    • Organizer
      第30回日本骨代謝学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] FGF23は軟骨細胞増殖をリン代謝非依存性に抑制し,X連鎖性低リン性くる病に伴う低身長の一因となりうる2012

    • Author(s)
      川井正信,木下さおり,大幡泰久,大薗惠一,道上敏美
    • Organizer
      第46回日本小児内分泌学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] 骨細胞と骨外臓器との連関2012

    • Author(s)
      道上敏美
    • Organizer
      第30回 日本骨代謝学会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] Hypマウスの骨においては胎児期より既にFgf23及びDmp1の発現が増加している2011

    • Author(s)
      宮川和晃,大薗惠一,大幡泰久,川井正信,立川加奈子,高垣裕子,古郷幹彦,道上敏美
    • Organizer
      第29回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] 1,25(OH)_2D and PTH up-regulate Rankl while down-regulate Phex and dmp1 in primary osteocytes isolated from mouse bones2011

    • Author(s)
      Miyagawa K, Ozono K, Tachikawa K, Kawai M, Mikuni-Takagaki Y, Kogo M, Michigami T
    • Organizer
      33^<th> Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] リン代謝調節細胞としての骨細胞の役割.2011

    • Author(s)
      道上敏美
    • Organizer
      第29回日本骨代謝学会学術集会(招待講演)
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] リン代謝調節細胞としての骨細胞の役割2011

    • Author(s)
      道上敏美
    • Organizer
      第29回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] Hypマウスの骨においては胎児期より既にFgf23及びDmp1の発現が増加している.2011

    • Author(s)
      宮川和晃,大薗惠一,大幡泰久,川井正信,立川加奈子,高垣裕子,古郷幹彦,道上敏美
    • Organizer
      第29回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] XLHモデルHypマウスにおける胎児血中リン値維持機構の存在-FGF23および胎盤の関与2011

    • Author(s)
      大幡泰久,宮川和晃,山﨑美和,岡田知子,川井正信,平井治彦,大薗惠一,道上敏美
    • Organizer
      第45回日本小児内分泌学会学術集会
    • Place of Presentation
      埼玉
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] 1,25(OH)2D and PTH up-regulate Rankl while down-regulate Phex and Dmp1 in primary osteocytes isolated from mouse bones.2011

    • Author(s)
      Miyagawa K, Ozono K, Tachikawa K, Kawai M, Mikuni-Takagaki Y, Kogo M, Michigami T
    • Organizer
      33th annual meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      San Diego, U.S.A.
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] 胎児期特異的ミネラル代謝調節機構におけるFGF23の関与─Hypマウスを用いた解析2011

    • Author(s)
      大幡泰久,三浦弘司,山﨑美和,岡田知子,川井正信,大薗惠一,道上敏美
    • Organizer
      第29回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] 胎児特異的リン代謝:リン経胎盤輸送からみた新知見2011

    • Author(s)
      大幡泰久,道上敏美,大薗惠一
    • Organizer
      第56回日本未熟児新生児学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] Analysis of the roles of FGF23 in fetus-specific mineral metabolism using Hyp mice2011

    • Author(s)
      Ohata Y, Miyagawa K,Yamazaki M, Okada T, Kawai M, Ozono K, Michigami T
    • Organizer
      IOF Regionals 2^<nd> Asis-Pacific Osteoporosis and Bone Meeting
    • Place of Presentation
      Gold Coast
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] Roles of osteocytes in phosphate homeostasis.2011

    • Author(s)
      Michigami T
    • Organizer
      The expert meeting from the Korean society of osteoporosis(招待講演)
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] Molecular mechanisms underlying the phosphate homeostasis.2011

    • Author(s)
      Michigami T.
    • Organizer
      The 15^<th> Congress of the International Pediatric Nephrology Association.
    • Place of Presentation
      New York, U.S.A.
    • Year and Date
      2011-09-01
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Presentation] Signal transduction triggered by extracellular inorganic phosphate involves FGF receptor and influences the FGF23 signaling.2010

    • Author(s)
      Yamazaki M, Ozono K, Okada T, Ohata Y, Tachikawa K, Kondou H, Michigami T.
    • Organizer
      14th International Congress of Endocrinology
    • Place of Presentation
      京都
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Presentation] Signaling of extracellular inorganic phosphate mediated via sodium-phosphate co-transporters influences FGF23 signaling in renal tubular cells.2008

    • Author(s)
      Yamazaki M, Okada T, Tachikawa K, Ozono K, Michigami T.
    • Organizer
      30th Annual Meeting of the American Society for Bone and Mineral Research.
    • Place of Presentation
      Montreal
    • Year and Date
      2008-09-14
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Presentation] ヒト胎児腎臓由来細胞株HEK293における細胞外無機リン酸シグナル伝達にはIII型Na^+/Pi共輸送担体Pit-1とFGF receptor substrate 2α(FRS2α)が関与する2008

    • Author(s)
      山崎美和,岡田知子,立川加奈子,大幡泰久,大薗惠一,道上敏美
    • Organizer
      第26回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2008-10-30
    • Data Source
      KAKENHI-PROJECT-20590986
  • [Presentation] Molecular basis of phosphate sensing in the early stage of chondrocyte differentiation.2006

    • Author(s)
      Kimata M, Tachikawa K, Ozono K, Kogo M, Michigami T.
    • Organizer
      28th annual meeting of the American Society for Bone and Mineral Researth
    • Place of Presentation
      Pennsylvania, U.S.A.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590921
  • [Presentation] Extracellular inorganic phosphate alters gene expression in early chondrocytes through phosphorylation of ERK.2006

    • Author(s)
      Kimata M, Tachikawa K, Ozono K, Kogo M, Michigami T.
    • Organizer
      3rd International Osteoporosis Foundation Asia-Pacific Regional Conference on Osteoporosis and 16th Annual Meeting Australian and New Zealand Bone and Mineral Society.
    • Place of Presentation
      Port Donglas, Australia
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590921
  • [Presentation] Extracellular inorganic phosphate induces ERK1/2 phosphorylation and up-regulates a target gene of FGF23 in renal proximal tubule cells via type IIa sodium-phosphate co-transporter.

    • Author(s)
      Yamazaki M, Kunata M, Tachikawa K, Ozono K, Michigami T.
    • Organizer
      29th annual meeting of the American Society for Bone and
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590921
  • [Presentation] 脂溶性ビタミン

    • Author(s)
      道上敏美
    • Organizer
      第13回新生児栄養フォーラム
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591227
  • [Presentation] 骨ミネラル代謝異常症の分子病態の解明をめざして

    • Author(s)
      道上敏美
    • Organizer
      第31回日本骨代謝学会学術集会
    • Place of Presentation
      神戸
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591227
  • 1.  OZONO Keiichi (20270770)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 4 results
  • 2.  MUSHIAKE Sotaro (90291947)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  YAMAZAKI Miwa (50455549)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 14 results
  • 4.  KONDOU Hiroki (10373515)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 5.  Kubota Takuo (40629135)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 6.  NAMBA Noriyuki (10379076)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  OKURA Masaya (10281130)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MATSUI Yoshito (80335348)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  樋口 周久 (62347000)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  村瀬 剛 (50335361)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  妻木 範行 (50303938)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  大幡 泰久 (20805460)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  岡田 随象 (70727411)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  柳原 格
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  川井 正信(カワイマサノブ)
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 16.  木下 さおり
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  大川 玲奈
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  古々本 一馬
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  榛葉 繁紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  岡野 登志夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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