MURAKAMI YOSHIKO 村上良子

… Alternative Names

村上良子ムラカミヨシコ

MURAKAMI Yoshiko 村上良子

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Researcher Number	00304048
Other IDs
Affiliation (Current)	2025: 大阪大学, 微生物病研究所, 特任教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 大阪大学, 微生物病研究所, 特任教授 2018: 大阪大学, 微生物病研究所・籔本難病解明寄附研究部門, 教授 2009 – 2016: 大阪大学, 微生物病研究所, 准教授 2007: Osaka University, Research Institute for Microbial Diseases, Assistant Professor 2005 – 2006: Osaka University, Research Institute for Microbial Diseases, Research Associate, 微生物病研究所, 助手 … More 2004: 大阪大学, 微生物病研究所, 教務職員 2003: 大阪大学, 教務職員 2002: Osaka University, Research Institute for Microbial Diseases, Technical Official, 微生物病研究所, 教務職員 2001: 大阪大学, 微生物病研究所, 教務技官 1999 – 2000: 大阪大学, 微生物病研究所, 教務職員 Less
Review Section/Research Field	Principal Investigator Hematology / Basic Section 43030:Functional biochemistry-related / Biological Sciences / Pathological medical chemistry Except Principal Investigator Structural biochemistry / Functional biochemistry / Basic Section 43020:Structural biochemistry-related / Pediatrics / Biological Sciences
Keywords	Principal Investigator PNH / GPI / Ras / HMGA2 / ビタミンB6 / GPIアンカー / 高アルカリホスファターゼ血症 / 発作性夜間ヘモグロビン尿症 / 高アルカリフォスファターゼ血症 / 精神運動発達障害 … More / てんかん / 先天性GPI欠損症 / ARV1 / グリコシルホスファチジルイノシトール / NアセチルグルコサミンPI / PIGQ / ホスファチジルイノシトール（PI) / ビタミンB1 / PIGA / clonal expansion / GPI アンカー / ビタミンB６ / ビタミンB１ / アルカリホスファターゼ / regulation of expression / carbohydrate / signal transduction / cells and tissues / genes / 発現制御 / 糖鎖 / シグナル伝達 / 細胞・組織 / 遺伝子 / Eri1p / Eri1 / RhoA / PIG-Y / Erilp / 乳児早期てんかん性脳症 / GPIアンカー型蛋白質 / 精神発達遅滞 / 深部静脈血栓症 / 溶血性貧血 / 補体制御因子 … More Except Principal Investigator GPIアンカー / 小胞体 / 生合成 / endoplasmic reticulum / GPI anchor / 糖転移酵素 / 翻訳後修飾 / 糖鎖 / 酵素 / 遺伝子 / グリコシルホスファチジルイノシトール / 活性化葉酸 / 先天性GPIアンカー欠損症 / てんかん / ピリドキシン / 先天性GPI欠損症 / raft / de-acylation / remodeling / transport / GPI-anchor / ラフト / 脱アシル化 / リモデリング / 輸送 / N結合型糖質 / 脂質 / 細胞・組織 / gene cloning / biosynthesis / glycolipid / post trarnslational modification / 塘脂質 / 遺伝子クローニング / 糖脂質 / post translational modification / 生合成経路 / GIPアンカー / 糖質 / タンパク質 Less

GPI生合成と脂質合成に関わるARV1の機能の解明Principal Investigator
- Principal Investigator
  
  村上良子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Osaka University
Mechanisms for regulation of glycosylphosphatidylinositol biosynthesis
- Principal Investigator
  
  Kinoshita Taroh
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Osaka University
Analysos of metabolic abnormality which causes clonal expansion in Paroxysmal nocturnal hemoglobinuriaPrincipal Investigator
- Principal Investigator
  
  Murakami Yoshiko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Osaka University
Devlopment of diagnostic marker and new treatment for inherited glycosylphosphatidylinositol anchored protein deficiency
- Principal Investigator
  
  KOJI TOMINAGA
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Osaka University
先天性GPI欠損症の疾患概念の確立と発症機序の解明Principal Investigator
- Principal Investigator
  
  村上良子
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Analysis for the molecular mechanism of Inheited GPI DeficiencyPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Yoshiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
Molecular mechanisms and functions of structural changes of protein GPI-anchors
- Principal Investigator
  
  KINOSHITA Taroh
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka University
Investigation of the mechanism for clonal expansion of GPI negative cells in paroxysmal nocturnal hemoglobinuriaPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Yoshiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
The regulation of functions and expressions of proteins by glycosylphosphatidylinositol-anchor
- Principal Investigator
  
  MAEDA Yusuke
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka University
Investigation into the mechanism for expansion of abnormal clone in paroxysmal nocturnal hemoglobinuriaPrincipal Investigator
- Principal Investigator
  
  MURAKAMI Yoshiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
GPIアンカー合成の調節機構と合成不全症
- Principal Investigator
  
  木下タロウ
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Biosynthesis pathway of GPI anchored proteins.
- Principal Investigator
  
  KINOSHITA Taroh
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka University
Mechanism of biosynthesis of protein GPI anchors.
- Principal Investigator
  
  KINOSHITA Taroh
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Structural biochemistry
- Research Institution
  OSAKA UNIVERSITY

[Book] Annual Review 血液 2008 先天性と後天性GPI欠損症2008
- Author(s)
  村上良子、木下タロウ
- Publisher
  中外医学者
- Data Source
  KAKENHI-PROJECT-18591060
[Book] 先天性GPI欠損症分子細胞治療 vol.7 no.12008
- Author(s)
  村上良子、木下タロウ
- Publisher
  先端医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Book] 先天性と後天性GPI欠損症 Annual Review 血液2008
- Author(s)
  村上良子、木下タロウ
- Publisher
  中外医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Book] Diseases associated with GPI anchors. In Comprehensive Glycoscience.2007
- Author(s)
  Kinoshita, T., Y. Murakami and Y. S. Morita.
- Publisher
  Elsevier Ltd. , Amsterdam.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Book] 発作性夜間血色素尿症を代表とするGPI病、実験医学増刊糖鎖研究 vol.25 No.72007
- Author(s)
  村上良子、木下タロウ
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Book] PNHクローン拡大の自己免疫反応による選択、最新・内科シリーズ Vision, 212007
- Author(s)
  村上良子
- Publisher
  株式会社インターメディカ
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Book] 実験医学糖鎖研究発作性夜間血色素尿症を代表とするGPI病2007
- Author(s)
  村上良子、木下タロウ
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18591060
[Journal Article] AAV-based gene therapy ameliorated CNS-specific GPI defect in mouse models2024
- Author(s)
  Murakami Yoshiko、Umeshita Saori、Imanishi Kae、Yoshioka Yoshichika、Ninomiya Akinori、Sunabori Takehiko、Likhite Shibi、Koike Masato、Meyer Kathrin C.、Kinoshita Taroh
- Journal Title
  
  Molecular Therapy - Methods & Clinical Development
  
  Volume: 32 Issue: 1 Pages: 101176-101176
- DOI
  10.1016/j.omtm.2023.101176
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06323, KAKENHI-PROJECT-21H02415
[Journal Article] Accumulated precursors of specific GPI-anchored proteins upregulate GPI biosynthesis with ARV1.2023
- Author(s)
  Liu, Y.-S., Y. Wang, X. Zhou, L. Zhang, X.-D. Gao, Y. Murakami, M. Fujita and T. Kinoshita.
- Journal Title
  
  J. Cell Biol.
  
  Volume: 222 Issue: 5 Pages: 1-20
- DOI
  10.1083/jcb.202208159
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05695, KAKENHI-PROJECT-21H02415
[Journal Article] Sequential hydrolysis of FAD by ecto-5′ nucleotidase CD73 and alkaline phosphatase is required for uptake of vitamin B2 into cells2022
- Author(s)
  Shichinohe Natsuki、Kobayashi Daisuke、Izumi Ayaka、Hatanaka Kazuya、Fujita Rio、Kinoshita Taroh、Inoue Norimitsu、Hamaue Naoya、Wada Keiji、Murakami Yoshiko
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 12 Pages: 102640-102640
- DOI
  10.1016/j.jbc.2022.102640
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02415
[Journal Article] Ethanolamine‐phosphate on the second mannose is a preferential bridge for some GPI‐anchored proteins2022
- Author(s)
  Ishida Mizuki、Maki Yuta、Ninomiya Akinori、Takada Yoko、Campeau Philippe、Kinoshita Taroh、Murakami Yoshiko
- Journal Title
  
  EMBO reports
  
  Volume: 23 Issue: 7
- DOI
  10.15252/embr.202154352
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02415
[Journal Article] Genome-wide CRISPR screen reveals CLPTM1L as a lipid scramblase required for efficient glycosylphosphatidylinositol biosynthesis2022
- Author(s)
  Wang Yicheng、Menon Anant K.、Maki Yuta、Liu Yi-Shi、Iwasaki Yugo、Fujita Morihisa、Guerrero Paula A.、Silva Daniel Varon、Seeberger Peter H.、Murakami Yoshiko、Kinoshita Taroh
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 14 Pages: 7211-7211
- DOI
  10.1073/pnas.2115083119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02415, KAKENHI-WRAPUP-22H04899
[Journal Article] Rescue of Glycosylphosphatidylinositol-Anchored Protein Biosynthesis Using Synthetic Glycosylphosphatidylinositol Oligosaccharides2021
- Author(s)
  Guerrero Paula A.、Murakami Yoshiko、Malik Ankita、Seeberger Peter H.、Kinoshita Taroh、Varon Silva Daniel
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 16 Issue: 11 Pages: 2297-2306
- DOI
  10.1021/acschembio.1c00465
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02415
[Journal Article] Differential use of p24 family members as cargo receptors for the transport of glycosylphosphatidylinositol-anchored proteins and Wnt12021
- Author(s)
  Tashima Yuko、Hirata Tetsuya、Maeda Yusuke、Murakami Yoshiko、Kinoshita Taroh
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 171 Issue: 1 Pages: 75-83
- DOI
  10.1093/jb/mvab108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02415
[Journal Article] phenotypes from infantile lethality to mild learning difficulties2017
- Author(s)
  Tanigawa J, Mimatsu H, Mizuno S, Okamoto N, Fukushi D, Tominaga K, Kidokoro H, Muramatsu Y, Nishi E, Nakamura S, Motooka D, Nomura N, Hayasaka K, Niihori T, Aoki Y, Nabatame S, Hayakawa M, Natsume J, Ozono K, Kinoshita T, Wakamatsu N, Murakami Y
- Journal Title
  
  Human Mutation
  
  Volume: 印刷中 Issue: 7 Pages: 805-815
- DOI
  10.1002/humu.23219
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01578, KAKENHI-PROJECT-26461543, KAKENHI-PROJECT-26462225, KAKENHI-PROJECT-15K09618, KAKENHI-PROJECT-17K10070, KAKENHI-PROJECT-16K15534
[Journal Article] 知的障害とてんかんを主症状とする新しい疾患―先天性GPI欠損症2015
- Author(s)
  村上良子　木下タロウ
- Journal Title
  
  脳と発達誌
  
  Volume: 47 Pages: 5-13
- NAID
  130005005752
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25129705
[Journal Article] Mutations in PIGL in a patient with Mabry syndrome.2015
- Author(s)
  Fujiwara I, Murakami Y, Niihori T, Kanno J, Hakoda A, Sakamoto O, Okamoto N, Funayama R, Nagashima T, Nakayama K, Kinoshita T, Kure S, Matsubara Y, Aoki Y.
- Journal Title
  
  Am J Med Genet A.
  
  Volume: in press Issue: 4 Pages: 777-785
- DOI
  10.1002/ajmg.a.36987
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25129705, KAKENHI-PROJECT-25461535, KAKENHI-PROJECT-26461520, KAKENHI-PROJECT-26830064, KAKENHI-PROJECT-15K15024, KAKENHI-PROJECT-26293059
[Journal Article] PIGA mutations cause early-onset epileptic encephalopathies and distinctive features2014
- Author(s)
  Kato M, Saitsu H, Murakami Y , Kikuchi K, Watanabe S, Iai M, Miya K, Matsuura R, Takayama R, Ohba C, Nakashima M, Tsurusaki Y, Miyake N, Hamano S, Osaka H, Hayasaka K, Kinoshita T, Matsumoto N.
- Journal Title
  
  Neurology
  
  Volume: 82（18） Issue: 18 Pages: 1587-1596
- DOI
  10.1212/wnl.0000000000000389
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118007, KAKENHI-PROJECT-24249019, KAKENHI-PUBLICLY-25129705, KAKENHI-PROJECT-25293085, KAKENHI-PROJECT-25293235, KAKENHI-PROJECT-25860915
[Journal Article] Null mutation in PGAP1 impairing Gpi-anchor maturation in patients with intellectual disability and encephalopathy.2014
- Author(s)
  Murakami, Y., H. Tawamie, Y. Maeda, C, Buttner, R. Buchert, F. Radwan, S. Schaffer, H. Sticht, M. Aigner, A. Reis, T. Kinoshita and R. A. Jamra.
- Journal Title
  
  PLoS Genet.
  
  Volume: 10 Issue: 5 Pages: e1004320-e1004320
- DOI
  10.1371/journal.pgen.1004320
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25129705
[Journal Article] Glycosylphosphatidylinositol (GPI) anchor deficiency caused by mutations in PIGW is associated with West syndrome and hyperphosphatasia with mental retardation syndrome.2014
- Author(s)
  Chiyonobu T, Inoue N, Morimoto M, Kinoshita T, and Murakami Y.
- Journal Title
  
  J Med Genet.
  
  Volume: 51 Issue: 3 Pages: 203-207
- DOI
  10.1136/jmedgenet-2013-102156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590363, KAKENHI-PROJECT-24501336, KAKENHI-PUBLICLY-25129705
[Journal Article] PIGO mutations in intractable epilepsy and severe developmental delay with mild elevation of alkaline phosphatase levels.2014
- Author(s)
  Nakamura, K.Osaka, H.Murakami, Y.Anzai, R.Nishiyama, K.Kodera, H.Nakashima, M.Tsurusaki, Y.Miyake, N.Kinoshita, T.Matsumoto, N. and Saitsu, H
- Journal Title
  
  Epilepsia
  
  Volume: 55 Issue: 2 Pages: 13-17
- DOI
  10.1111/epi.12508
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25129705, KAKENHI-PROJECT-25293085, KAKENHI-PROJECT-25293235, KAKENHI-PROJECT-25860915, KAKENHI-PROJECT-26860816
[Journal Article] Clinical whole-genome sequencing in severe early-onset epilepsy reveals new genes and improves molecular diagnosis.2014
- Author(s)
  Martin, H. C., G. Kim, A. T. Pagnamenta, Y. Murakami, et al
- Journal Title
  
  Hum. Mol. Genet.
  
  Volume: 23 Issue: 12 Pages: 3200-3211
- DOI
  10.1093/hmg/ddu030
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25129705
[Journal Article] PIGN mutations cause congenital anomalies, developmental delay, hypotonia, epilepsy, and progressive cerebellar atrophy2014
- Author(s)
  Ohba C, Okamoto N, Murakami Y, Kawato K, Suzuki Y, Ikeda T, Tsurusaki Y, Nakashima M, Miyake N, Tanaka F, Kinoshita T, Matsumoto N, Saitsu H .
- Journal Title
  
  Neurogenet
  
  Volume: 15（2） Issue: 2 Pages: 85-92
- DOI
  10.1007/s10048-013-0384-7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118007, KAKENHI-PROJECT-24249019, KAKENHI-PUBLICLY-25129705, KAKENHI-PROJECT-25293235, KAKENHI-PROJECT-25860915
[Journal Article] Mutations in PGAP3 impair GPI-anchor maturation and lead to intellectual disability with hyperphosphatasia and additional phenotypic features.2014
- Author(s)
  Howard MF* Murakami Y* Pagnamenta AT, Haas CD, Fischer B, Hecht J, Keays DA, Knight SJL, Kolsch U, Kruger U, Leiz S, Maeda Y, Mitchell D, Mundlos S, Philipps JA, Robinson PN, Kini U, Taylor JC, Horn D, Kinoshita T, and Krawitz PM. （*equally contribution)
- Journal Title
  
  Am J Hum Genet
  
  Volume: 94 Issue: 2 Pages: 278-287
- DOI
  10.1016/j.ajhg.2013.12.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590363, KAKENHI-PUBLICLY-25129705
[Journal Article] Novel compound heterozygous PIGT mutations caused multiple congenital anomalies-hypotonia-seizures syndrome 32014
- Author(s)
  Nakashima M, Kashii H, Murakami Y, Kato M, Tsurusaki Y, Miyake N, Kubota M, Kinoshita T, Saitsu H, Matsumoto N.
- Journal Title
  
  Neurogenet
  
  Volume: 15（3） Issue: 3 Pages: 193-200
- DOI
  10.1007/s10048-014-0408-y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118007, KAKENHI-PROJECT-24249019, KAKENHI-PUBLICLY-25129705, KAKENHI-PROJECT-25293085, KAKENHI-PROJECT-25293235, KAKENHI-PROJECT-25860874, KAKENHI-PROJECT-25860915
[Journal Article] Case report with vitamin B6 responsive epilepsy due to inherited GPI deficiency.2013
- Author(s)
  Kuki, I., Y. Takahashi, Okazaki, Ebara, N. Inoue, T. Kinoshita and Y. Murakami.
- Journal Title
  
  Neurology
  
  Volume: 81 Issue: 16 Pages: 1467-1469
- DOI
  10.1212/wnl.0b013e3182a8411a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590363, KAKENHI-PROJECT-24501336, KAKENHI-PUBLICLY-25129705
[Journal Article] Glycosylphosphatidylinositol mannosyltransferase II is the rate-limiting enzyme in glycosylphosphatidylinositol biosynthesis under limited dolichol-phosphate mannose availability2013
- Author(s)
  Hirata, T., M. Fujita, N. Kanzawa, Y. Murakami, Y. Maeda and T. Kinoshita
- Journal Title
  
  J. Bio chem
  
  Volume: 154 Issue: 3 Pages: 257-264
- DOI
  10.1093/jb/mvt045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247018, KAKENHI-PROJECT-23687017, KAKENHI-PROJECT-25860238
[Journal Article] Hypomorphic Mutations in PGAP2, Encoding a GPI-Anchor-Remodeling Protein, Cause Autosomal-Recessive Intellectual Disability2013
- Author(s)
  Hansen, L. Tawamie, H. Murakami, Y. Mang, Y. Ur Rehman, S. Buchert, R. Schaffer, S. Muhammad, S. Bak, M. Nothen, M. M. Bennett, E. P. Maeda, Y. Aigner, M. Reis, A. Kinoshita, T. et al.
- Journal Title
  
  Am J Hum Genet
  
  Volume: 92(4) Issue: 4 Pages: 575-583
- DOI
  10.1016/j.ajhg.2013.03.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590363, KAKENHI-PUBLICLY-25129705
[Journal Article] A case of paroxysmal nocturnal hemoglobinuria (PNH) caused by a germline mutation and a somatic mutation in PIGT2013
- Author(s)
  Krawitz, P. M., B. Hochsmann, Y. Murakami, B. Teubner, U. Kruger, E. Klopocki, H. Neitzel, A. Hollein, D. Parkhomchuk, J. Hecht, P. N. Robinson, S. Mundlos, T. Kinoshita and H. Schrezenmeier
- Journal Title
  
  Blood
  
  Volume: 122 Issue: 7 Pages: 1312-1315
- DOI
  10.1182/blood-2013-01-481499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247018, KAKENHI-PROJECT-23590363
[Journal Article] PGAP2 Mutations, Affecting the GPI-Anchor-Synthesis Pathway, Cause Hyperphosphatasia with Mental Retardation Syndrome2013
- Author(s)
  Krawitz, P. M. Murakami, Y. Riess, A. Hietala, M. Kruger, U. Zhu, N. Kinoshita, T. Mundlos, S. Hecht, J. Robinson, P. N. Horn, D.
- Journal Title
  
  Am J Hum Genet
  
  Volume: 92(4) Issue: 4 Pages: 584-589
- DOI
  10.1016/j.ajhg.2013.03.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590363, KAKENHI-PUBLICLY-25129705
[Journal Article] Significance of GPI-anchored protein enrichment in lipid rafts for the control of autoimmunity2013
- Author(s)
  Wang, Y., Y. Murakami, T. Yasui, S. Wakana, H. Kikutani, T. Kinoshita and Y. Maeda
- Journal Title
  
  J. Biol. Chem
  
  Volume: 288 Issue: 35 Pages: 25490-25499
- DOI
  10.1074/jbc.m113.492611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247018, KAKENHI-PROJECT-23370060, KAKENHI-PROJECT-24590550
[Journal Article] Occupancy of whole blood cells by a single PIGA-mutant clone with HMGA2 amplification in a paroxysmal nocturnal haemoglobinuria patient having blood cells with NKG2D ligands2013
- Author(s)
  Hanaoka, N., Y. Murakami, M. Nagata, K. Horikawa, S. Nagakura, Y. Yonemura, S. Murata, T. Sonoki, T. Kinoshita, H. Nakakuma
- Journal Title
  
  Br. J. Haematol.
  
  Volume: 160 Issue: 1 Pages: 114-116
- DOI
  10.1111/bjh.12093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590363, KAKENHI-PROJECT-23791087
[Journal Article] Deregulated expression of HMGA2 is implicated in clonal expansion of PIGA deficient cells in paroxysmal nocturnal haemoglobinuria.2012
- Author(s)
  Murakami Y, Inoue N, Shichishima T, Ohta R, Noji H, Maeda Y, Nishimura J, Kanakura Y, Kinoshita T.
- Journal Title
  
  Br J Haematol.
  
  Volume: 156 Pages: 383-387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590363
[Journal Article] Deregulated expression of HMGA2 is implicated in clonal expansion of PIGA deficient cells in paroxysmal nocturnal haemoglobinuria2012
- Author(s)
  Murakami, Y., N. Inoue, T. Shichishima, R. Ohta, H. Noji, Y. Maeda, J. Nishimura, Y. Kanakura and T. Kinoshita
- Journal Title
  
  Br. J. Haematol
  
  Volume: 156 Issue: 3 Pages: 383-387
- DOI
  10.1111/j.1365-2141.2011.08914.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247018, KAKENHI-PROJECT-21590326, KAKENHI-PROJECT-22390194, KAKENHI-PROJECT-22591044, KAKENHI-PROJECT-22591067, KAKENHI-PROJECT-22791813, KAKENHI-PROJECT-23590363
[Journal Article] Mutations in PIGO, a member of the GPI anchor synthesis pathway, cause hyperphosphatasia with mental retardation2012
- Author(s)
  Krawitz, P. M., Y. Murakami, J. Hecht, U. Kruger, S. E. Holder, G. R. Mortier, B. delle Chiaie, M. D. Thompson, T. Roscioli, S. Kielbasa, T. Kinoshita, S. Mundlos, P. N. Robinson and D. Horn
- Journal Title
  
  Am. J. Hum. Genet
  
  Volume: 91 Issue: 1 Pages: 146-151
- DOI
  10.1016/j.ajhg.2012.05.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247018, KAKENHI-PROJECT-23590363
[Journal Article] Persistently high quality of life conferred by coexisting congenital deficiency of terminal complement C9 in a paroxysmal nocturnal hemoglobinuria patient.2012
- Author(s)
  Hanaoka N, Murakami Y, Nagata M, Nagakura S, Yonemura Y, Sonoki T, Kinoshita T, Nakakuma H.
- Journal Title
  
  Blood
  
  Volume: 119(16) Issue: 16 Pages: 3866-3868
- DOI
  10.1182/blood-2012-02-408161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590363, KAKENHI-PROJECT-23791087
[Journal Article] Mechanism for release of alkaline phosphatase caused by glycosylphosphatidylinositol deficiency in patients with hyperphosphatasia-mental retardation syndrome2012
- Author(s)
  Murakami, Y., N. Kanzawa, K. Saito, P. M. Krawitz, S. Mundlos, P. N. Robinson, A. Karadimitris, Y. Maeda and T. Kinoshita
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Issue: 9 Pages: 6318-6325
- DOI
  10.1074/jbc.m111.331090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247018, KAKENHI-PROJECT-23590363, KAKENHI-PROJECT-23790365
[Journal Article] Mechanism for release of alkaline phosphatase caused by glycosylphosphatidylinositol deficiency in patients with hyperphosphatasia mental retardation syndrome.2012
- Author(s)
  Murakami Y, Kanzawa N, Saito K, Krawitz PM, Mundlos S, Robinson PN, Karadimitris A, Maeda Y, Kinoshita T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 287 Pages: 6318-6325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590363
[Journal Article] Enhanced response of T lymphocytes from Pgap3 knockout mouse : Insight into roles of fatty acid remodeling of GPI anchored proteins2012
- Author(s)
  Murakami, H., Y. Wang, H. Hasuwa, Y. Maeda, T. Kinoshita and Y. Murakami
- Journal Title
  
  Biochem. Biophys. Res. Comm
  
  Volume: 417 Issue: 4 Pages: 1235-1241
- DOI
  10.1016/j.bbrc.2011.12.116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247018
[Journal Article] Enhanced response of T lymphocytes from Pgap3 knockout mouse : Insightinto roles of fatty acid remodeling of GPI anchored proteins2012
- Author(s)
  Murakami, H.
- Journal Title
  
  Biochem.Biophys.Res.Comm.
  
  Volume: 417 Pages: 1235-1241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247018
[Journal Article] Defective lipid remodeling of GPI anchors in peroxisomal disorders, Zellweger syndrome and rhizomelic chondrodysplasia punctata2012
- Author(s)
  Kanzawa, N., et al.
- Journal Title
  
  Journal of Lipid Research
  
  Volume: 53 Issue: 4 Pages: 653-663
- DOI
  10.1194/jlr.m021204
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058011, KAKENHI-PROJECT-21247018, KAKENHI-PROJECT-21591318, KAKENHI-PROJECT-23790365, KAKENHI-PROJECT-24247038, KAKENHI-PROJECT-24390261
[Journal Article] Controlled expression of branch-forming mannosyltransferase is critical for mycobacterial lipoarabinomannan biosynthesis2010
- Author(s)
  Sena, C. B., T. Fukuda, K. Miyanagi, S. Matsumoto, K. Kobayashi, Y. Murakami, Y. Maeda, T. Kinoshita and Y. S. Morita
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Issue: 18 Pages: 13326-13336
- DOI
  10.1074/jbc.m109.077297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247018
[Journal Article] Peroxisome dependency of alkyl-containing GPI-anchor biosynthesis in the endoplasmic reticulum2009
- Author(s)
  Kanzawa, N., Y. Maeda, H. Ogiso, Y. Murakami, R. Taguchi, and T. Kinoshita
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 106 Issue: 42 Pages: 17711-17716
- DOI
  10.1073/pnas.0904762106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247018
[Journal Article] Research in Japan has contributed to the understanding of GPI anchor deficiency2007
- Author(s)
  Murakami, Y., T., Kinoshita
- Journal Title
  
  In Glycoscience Lab Manual. Ed., Springer, Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Journal Article] (* equally contributed) Targeted therapy for inherited GPI deficiency2007
- Author(s)
  Almeida, A M., Y., Murakami, A., Baker, Y., Maeda, I., A G., Roberts, T., Kinoshita, D M., Layton, A., Karadimitris
- Journal Title
  
  N. Engl. J. Med 356
  
  Pages: 1641-1647
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Journal Article] Targeted Therapy for Inherited GPI Deficiency2007
- Author(s)
  Almeida, A. M., *Y. Murakami*, A. Baker, Y. Maeda, I. A. G. Roberts, T. Kinoshita, D. M. Layton, and A. Karadimitris.(*equally contributed)
- Journal Title
  
  N Engl J Med. 356・16
  
  Pages: 1641-1647
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591060
[Journal Article] Molecular basis of clonal expansion of hematopoiesis in two patients with paroxysmal nocturnal hemoglobinuria (PNH)2006
- Author(s)
  Inoue, N., T., Izui-Sarumaru, Y., Murakami, Y., Endo, J., Nishimura, K., Kurokawa, M., Kuwayama, H., Shime, T., Machii, Y., Kanakura, G., Meyers, C., Wittwer, Z., Chen, W., Babcock, D., Frei-Lahr, C., Parker, T., Kinoshita
- Journal Title
  
  Blood 108
  
  Pages: 4232-4236
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Journal Article] The Initial Enzyme for Glycosylphosphatidylinositol Biosynthesis Requires PIG-Y, a Seventh Component.2006
- Author(s)
  Murakami, Y.
- Journal Title
  
  Mot.Biol.Cell 16
  
  Pages: 5236-5246
- Data Source
  KAKENHI-PROJECT-14082205
[Journal Article] Molecular basis of clonal expansion. of hematopoiesis in two patients with paroxysmal nocturnal hemoglobinuria(PNH).2006
- Author(s)
  Inoue, N., T. Izui-Sarumaru, Y. Murakami, Y. Endo, J. Nishimura, K. Kurokawa, M. Kuwayama, H. Shime, T. Machii, Y. Kanakura, G. Meyers, C. Wittwer, Z. Chen, W. Babcock, D. Frei-Lahr, C. Parker and T. Kinoshita.
- Journal Title
  
  Blood 108・13
  
  Pages: 4232-4236
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591060
[Journal Article] Hypomorphic promoter mutation in the mannosyltransfbrase-encoding PIG-M gene causes inherited glycosylphosphatidylinositol deficiency.2006
- Author(s)
  Almeida, A., *Y. Murakami*, M. Layton, P. Hillmen, G. S. Sellick, Y. Maeda, S. Richards, S. Patterson, I. Kotsianidis, L. Mollica, D. Crawford, A. Baker, M. Ferguson, I. Roberts, R. Houlston, T. Kinoshita and A. Karadimitris.(*equally contributed)
- Journal Title
  
  Nat. Med., 12
  
  Pages: 846-851
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591060
[Journal Article] (*equally contributed) Hypomorphic promoter mutation in the mannosyltransferase-encoding PIG-Mgene causes inherited glycosylphosphatidylinositol deficiency2006
- Author(s)
  Almeida, A., Y., Murakami, M., Layton, P., Hillmen, G S., Sellick, Y., Maeda, S., Richards, S., Patterson, I., Kotsianidis, L., Mollica, D., Crawford, A., Baker, M., Ferguson, I., Roberts, R., Houlston, T., Kinoshita, A., Karadimitris
- Journal Title
  
  Nat. Med 12
  
  Pages: 846-851
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Journal Article] The Initial Enzyme for Glycosylphosphatidylinositol Biosynthesis Requires PIG-Y, a Seventh Component.2005
- Author(s)
  Murakami, Y.
- Journal Title
  
  Mol.Biol.Cell 16
  
  Pages: 5236-5246
- Data Source
  KAKENHI-PROJECT-16570116
[Journal Article] The initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-Y, a seventh component.2005
- Author(s)
  Yoshiko Murakami
- Journal Title
  
  Mol.Biol.Cell 16
  
  Pages: 5236-5246
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570116
[Journal Article] The Initial Enzyme for Glycosylphosphatidylinositol Biosynthesis Requires PIG-Y, a Seventh Component.2005
- Author(s)
  Murakami, Y., et al.
- Journal Title
  
  Mol Biol Cell. 16
  
  Pages: 5236-5246
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570116
[Journal Article] The initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-Y, a seventh component.2005
- Author(s)
  Murakami, Y.
- Journal Title
  
  Mol.Biol.Cell 16
  
  Pages: 5236-5246
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590940
[Journal Article] The initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-Y, a seventh component.2005
- Author(s)
  Murakami, Y
- Journal Title
  
  Mol. Biol. Cell. 16
  
  Pages: 5236-5246
- Data Source
  KAKENHI-PROJECT-14082205
[Presentation] ARV1, an ER-resident lipid homeostasis regulator, associates with and enhances activity of the initial enzyme of GPI biosynthesis2023
- Author(s)
  TianTian Lu, Yoshiko Murakami, Taroh Kinoshita
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K05695
[Presentation] ARV1, an ER-resident lipid homeostasis regulator, associates with and enhances activity of the initial enzyme of GPI biosynthesis2023
- Author(s)
  TianTian Lu, Yoshiko Murakami, Taroh Kinoshita
- Organizer
  第42回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-23K05695
[Presentation] 先天性GPIアンカー欠損症における血清ALP値の検討2017
- Author(s)
  富永康仁　谷河純平　山下朋代　広恒実加　渡辺陽和　岩谷祥子　下野九理子　青天目信　村上良子　木下タロウ　永井利三郎　大薗恵一
- Organizer
  第59回日本小児神経学会
- Data Source
  KAKENHI-PROJECT-15K09618
[Presentation] 補体関連の遺伝子異常についてー補体制御因子の異常を中心にー2016
- Author(s)
  村上良子
- Organizer
  第６８回日本臨床化学会近畿支部例会
- Place of Presentation
  神戸常盤大学
- Year and Date
  2016-07-09
- Invited
- Data Source
  KAKENHI-PROJECT-15K15362
[Presentation] Clinical spectrum of PIGO mutations2016
- Author(s)
  谷河純平　村上良子　富永康仁　青天目信　見松はるか　城所博之　早川昌弘　水野誠司　若松延昭　岡本伸彦　夏目淳　木下タロウ　大薗恵一
- Organizer
  第58回日本小児神経学会
- Place of Presentation
  東京
- Year and Date
  2016-06-03
- Data Source
  KAKENHI-PROJECT-15K09618
[Presentation] Paroxysmal nocturnal hemoglobinuria caused by PIGT mutations; Atypical PNH2016
- Author(s)
  Yoshiko Murakami, Michi Kawamoto, Norimitsu Inoue, Makiko Osato, Shogo Murata, Sho Murase, Hajime Yoshimura, Yasutaka Ueda, Jun-ichi Nishimura, Yuzuru Kanakura, Nobuo Kohara, and Taroh Kinoshita
- Organizer
  The 58th ASH Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2016-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15362
[Presentation] 発作性夜間ヘモグロビン尿症2016
- Author(s)
  村上良子
- Organizer
  第７８回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-15K15362
[Presentation] Paroxysmal nocturnal hemoglobinuria caused by PIGT mutations; Atypical PNH2016
- Author(s)
  Yoshiko Murakami, Norimitsu Inoue, Michi Kawamotoi, Nobuo Kohara, Taroh Kinoshita
- Organizer
  The XXVI　International Complement Workshop
- Place of Presentation
  金沢
- Year and Date
  2016-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15362
[Presentation] 16年間延べ121回にわたる反復性無菌性髄膜炎にPIGT変異によるPNHを合併しEculizumabが著効した一例　その２　分子メカニズム2015
- Author(s)
  村上良子
- Organizer
  第52回日本補体学会学術集会
- Place of Presentation
  名古屋大学医学部
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-15K15362
[Presentation] Inherited GPI-anchor deficiencies caused by the hypomorphic mutations in PIGA gene: comparison to paroxysmal nocturnal hemogrobinuria2013
- Author(s)
  Yoshiko Murakami, Mitsuhiro Kato, Hirotomo Saitsu, Kenjiro Kikuchi, Shuei, Watanabe, Mizue Iai, Ryuki Matsuura, Rumiko Takayama, Chihiro Ohba, Shin-ichiro Hamano, Hitoshi Osaka, Kiyoshi Hayasaka, Naomichi Matsumoto, Taroh Kinoshita
- Organizer
  55^<th> ASH Annual Meeting and Exposition
- Place of Presentation
  New Orleans, LA USA
- Year and Date
  2013-12-09
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] 精神発達遅滞・てんかんを主症状とする疾患2013
- Author(s)
  村上良子、　井上徳光、　九鬼一郎、　高橋幸利、木下タロウ
- Organizer
  第50回補体シンポジウム
- Place of Presentation
  旭川医科大学
- Data Source
  KAKENHI-PUBLICLY-25129705
[Presentation] 高アルカリフォスファターゼ血症を呈する先天性GPI欠損症–肢根型点状軟骨異形成症との関連についての最近の知見も含めて2013
- Author(s)
  村上良子
- Organizer
  第17回大阪小児骨系統疾患研究会
- Place of Presentation
  大阪市
- Year and Date
  2013-02-16
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] 精神発達遅延・てんかんを主症状とする疾患：先天性GPI欠損症の疾患概念の確立に向けて2013
- Author(s)
  村上良子、井上徳光、九鬼一郎、高橋幸利、木下タロウ
- Organizer
  第55回日本小児神経学会学術集会
- Place of Presentation
  大分市
- Data Source
  KAKENHI-PUBLICLY-25129705
[Presentation] 先天性GPI欠損症―発達障害・てんかんを主症状とする新たな疾患―2013
- Author(s)
  村上良子
- Organizer
  第7回南大阪遺伝診療研究会
- Place of Presentation
  ホテル・アゴーラリージェンシー堺
- Invited
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] Inherited GPI-anchor deficiencies caused by the hypomorphic mutations in PIGA gene: comparison to paroxysmal nocturnal hemogrobinuria2013
- Author(s)
  Yoshiko Murakami
- Organizer
  55th ASH Annual Meeting and Exposition
- Place of Presentation
  米国ニューオリンズ市
- Data Source
  KAKENHI-PROJECT-21247018
[Presentation] Shedding of GPI-anchored proteins by a GPI-cleaving enzyme2013
- Author(s)
  Morihisa Fujita, Gun-Hee Lee, Yoshiko Murakami, Yusuke Maeda, and Taroh Kinoshita
- Organizer
  22nd International Symposium on Glycoconjugates
- Place of Presentation
  大連 Dalian Institute of Chemical Physics
- Data Source
  KAKENHI-PUBLICLY-25129705
[Presentation] 先天性GPI欠損症——発達障害・てんかんを主症状とする新たな疾患——2013
- Author(s)
  村上良子
- Organizer
  第7回南大阪遺伝診療研究会
- Place of Presentation
  堺市
- Year and Date
  2013-09-27
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] 精神発達遅延・てんかんを主症状とする疾患:先天性GPI欠損症の疾患概念の確立に向けて2013
- Author(s)
  村上良子, 井上徳光, 九鬼一郎, 高橋幸利, 木下タロウ
- Organizer
  第55回日本小児神経学会学術集会
- Place of Presentation
  大分市
- Year and Date
  2013-05-31
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] 精神発達遅滞・てんかんを主症状とする疾患2013
- Author(s)
  村上良子、　井上徳光、　九鬼一郎、　高橋幸利、木下タロウ
- Organizer
  第50回補体シンポジウム
- Place of Presentation
  旭川医科大学
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] Inherited GPI-anchor deficiencies caused by the hypomorphic mutations in PIGA gene: comparison to paroxysmal nocturnal hemogrobinuria2013
- Author(s)
  Yoshiko Murakami, Mitsuhiro Kato, Hirotomo Saitsu, Kenjiro Kikuchi, Shuei, Watanabe, Mizue Iai, Ryuki Matsuura, Rumiko Takayama, Chihiro Ohba, Shin-ichiro Hamano, Hitoshi Osaka, Kiyoshi Hayasaka, Naomichi Matsumoto, Taroh Kinoshita,
- Organizer
  55th ASH Annual Meeting and Exposition
- Place of Presentation
  New Orleans, LA USA
- Data Source
  KAKENHI-PUBLICLY-25129705
[Presentation] 精神発達遅延・てんかんを主症状とする疾患：先天性GPI欠損症の疾患概念の確立に向けて2013
- Author(s)
  村上良子、井上徳光、九鬼一郎、高橋幸利、木下タロウ
- Organizer
  第55回日本小児神経学会学術集会
- Place of Presentation
  大分市
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] GPIアンカー生合成に関与する遺伝子群の解析2013
- Author(s)
  藤田盛久, 中村昇太, 平田哲也, 村上良子, 前田裕輔, 木下タロウ
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜市
- Year and Date
  2013-09-12
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] 精神発達遅滞・てんかんを主症状とする疾患2013
- Author(s)
  村上良子, 井上徳光, 九鬼一郎, 高橋幸利, 木下タロウ
- Organizer
  第50回補体シンポジウム
- Place of Presentation
  旭川市
- Year and Date
  2013-07-06
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] Inherited GPI-anchor deficiencies caused by the hypomorphic mutations in PIGA gene: comparison to paroxysmal nocturnal hemogrobinuria2013
- Author(s)
  Yoshiko Murakami, Mitsuhiro Kato, Hirotomo Saitsu, Kenjiro Kikuchi, Shuei, Watanabe, Mizue Iai, Ryuki Matsuura, Rumiko Takayama, Chihiro Ohba, Shin-ichiro Hamano, Hitoshi Osaka, Kiyoshi Hayasaka, Naomichi Matsumoto, Taroh Kinoshita,
- Organizer
  55th ASH Annual Meeting and Exposition
- Place of Presentation
  New Orleans, LA USA.
- Invited
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] GPIアンカー生合成に関与する遺伝子群の解析2013
- Author(s)
  藤田盛久、中村昇太、平田哲也、村上良子、前田裕輔、木下タロウ
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] 藤田盛久、中村昇太、平田哲也、村上良子、前田裕輔、木下タロウ2013
- Author(s)
  平田哲也、　藤田盛久、村上良子、前田裕輔、木下タロウ
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-25129705
[Presentation] 先天性GPI欠損症ー発達障害・てんかんを主症状とする新たな疾患2013
- Author(s)
  村上良子
- Organizer
  第7回南大阪遺伝診療研究会
- Place of Presentation
  ホテル・アゴーラリージェンシー堺
- Invited
- Data Source
  KAKENHI-PUBLICLY-25129705
[Presentation] 先天性GPI欠損症—てんかん・発達障害を主症状とする新たな疾患概念の確立2012
- Author(s)
  村上良子
- Organizer
  第78回大阪小児神経懇話会
- Place of Presentation
  大阪市
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] 先天性GPI欠損症 -疾患概念の確立に向けて-2012
- Author(s)
  村上良子、井上徳光、高橋幸利、木下タロウ
- Organizer
  第３５回分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] 発作性夜間血色素尿症におけるGPI欠損細胞の拡大機序について2012
- Author(s)
  村上良子、井上徳光、金倉譲、西村純一、木下タロウ
- Organizer
  第49回補体シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] 先天性GPI欠損症てんかん・発達障害を主症状とする新たな疾患2012
- Author(s)
  村上良子
- Organizer
  関西ディスモルフォロジー研究会
- Place of Presentation
  大阪市
- Year and Date
  2012-09-01
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] Screening patients with inherited GPI anchor deficiency to establish concept of the new disease.2012
- Author(s)
  Yoshiko Murakami
- Organizer
  XXIV International Complement Workshop
- Place of Presentation
  ギリシャ国ハニア市
- Data Source
  KAKENHI-PROJECT-21247018
[Presentation] GPI アンカー型タンパク質の切断に関与する新規酵素の機能解析2012
- Author(s)
  藤田盛久, 李健熺, 村上良子, 前田裕輔, 木下タロウ
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島市民文化ホール
- Data Source
  KAKENHI-PROJECT-21247018
[Presentation] Screening patients with inherited GPI anchor deficiency to establish concept of the new disease2012
- Author(s)
  Yoshiko Murakami, Norimitsu Inoue, Yusuke Maeda, Yukitoshi Takahashi, Taroh Kinoshita
- Organizer
  XXIV International Complement Workshop
- Place of Presentation
  クレタ島ギリシャ
- Year and Date
  2012-10-12
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] Screening patients with inherited GPI anchor deficiency to establish concept of the new disease2012
- Author(s)
  Yoshiko Murakami, Norimitsu Inoue, Yusuke Maeda, Yukitoshi Takahashi, Taroh Kinoshita
- Organizer
  XXIV International Complement Workshop
- Place of Presentation
  クレタ島ギリシャ
- Year and Date
  2012-10-12
- Data Source
  KAKENHI-PROJECT-21247018
[Presentation] Screening patients with inherited GPI anchor deficiency to establish concept of the new disease2012
- Author(s)
  Yoshiko Murakami, Norimitsu Inoue, Yusuke Maeda, Yukitoshi Takahashi and Taroh Kinoshita
- Organizer
  XXIV International Complement Workshop
- Place of Presentation
  Chania, Greece
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] 先天性GPI欠損症-疾患概念の確率に向けて—Screening patients with inhierited GPI anchor deficiency to establish cincept of the new disease2012
- Author(s)
  村上良子, 井上徳光, 高橋幸利, 木下タロウ
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡市
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] 補体研究:基礎から臨床へ発作性夜間血色素尿症をはじめとするGPI欠損症について2011
- Author(s)
  村上良子, 井上徳光, 七島勉, 太田里永子, 野地秀義, 前田裕輔, 西村純一, 木下タロウ
- Organizer
  第48回補体シンポジウム
- Place of Presentation
  名古屋市(特別企画シンポジウム)
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] 発作性夜間血色素尿症をはじめとするGPI欠損症について2011
- Author(s)
  村上良子、太田里永子、井上徳光、木下タロウ
- Organizer
  第４８回補体シンポジウム「補体研究：基礎から臨床へ」(招待講演)
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] Release of alkaline phosphatase caused by PIGV mutations in patients with Hyperphosphatasia-Mental Retardation syndrome (HPMR), a recently found second inherited GPI anchor deficiency2011
- Author(s)
  Yoshiko Murakami, Peter M. Krawitz, Peter N. Robinson, Stefan Mundlos, Noriyuki Kanzawa, Yusuke Maeda, Taroh Kinoshita
- Organizer
  Glyco 21 (21th International Symposium on Glyconjugates)
- Place of Presentation
  ウィーン, オーストリア
- Year and Date
  2011-08-22
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] Release of alkaline phosphatase caused by PIGVmutations in patients with Hyperphosphatasia-Mental Retardation syndrome (HPMR), recently found second inherited GPI anchor deficiency.2011
- Author(s)
  Murakami,Y., Krawitz, PM., Robinson, PN, Mundlos, S., Maeda Y., and Kinoshita,T.
- Organizer
  Glyco 21
- Place of Presentation
  ウィーン
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] 遺伝性GPIアンカー欠損症と治療について2007
- Author(s)
  村上良子、前田裕輔、Antonio Almeida、Anastasios Karadimitris、木下タロウ
- Organizer
  第44回補体シンポジウム
- Place of Presentation
  平塚市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Presentation] 遺伝性GPIアンカー欠損症と治療について2007
- Author(s)
  村上良子
- Organizer
  第44回補体シンポジウム
- Place of Presentation
  東海大学松前記念館
- Year and Date
  2007-08-24
- Data Source
  KAKENHI-PROJECT-18591060
[Presentation] 遺伝性GPIアンカー欠損症2006
- Author(s)
  木下タロウ、村上良子、前田裕輔、Antonio Almeida、 Anastasios Karadimitris
- Organizer
  第43回補体シンポジウム
- Place of Presentation
  福岡
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Presentation] A point mutation in an Spl binding motif in the promoter of the mannosyltransferase-encoding PIG-Mgene causes inherited glycosylphosphatidylinositol deficiency2006
- Author(s)
  Yoshiko, Murakami, Antonio, Almeida, Mark, Layton, Peter, Hillmen, Yusuke, Maeda, Anastasios, Karadimitris, Taroh, Kinoshita
- Organizer
  XXIth International Complement Workshop
- Place of Presentation
  Beijing China
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Presentation] 遺伝性GPIアンカー欠損症の2家系2006
- Author(s)
  村上良子、前田裕輔、木下タロウ
- Organizer
  第68回日本血液学会総会第48回日本臨床血液学会合同総会
- Place of Presentation
  福岡
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Presentation] A point mutation in an Sp1 binding motif in the promoter of the mannosyltransferase-encoding PIG-M gene causes inherited glycosylphosphatidylinositol deficiency.2006
- Author(s)
  Yoshiko Murakami, Antonio Almeida, Mark Layton, Peter Hillmen, Yusuke Maeda, Anastasios Karadimitris and Taroh Kinoshita
- Organizer
  XXIth International Complement Workshop
- Place of Presentation
  Beijing China
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Presentation] A point mutation in an Sp1 binding motif in the promoter of the mannosyltransferase-encoding PIG-M gene causes inherited glycosylphosphatid ylinositol deficiency.2006
- Author(s)
  Yoshiko Murakami, Antonio Almeida, Mark Layton, Peter Hillmen, Yusuke Maeda, Anastasios Karadimitris and Taroh Kinoshita
- Organizer
  20th IUBMB International Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Presentation] A point mutation in an Spl binding motif in the promoter of the mannosyltransferase-encoding PIG-M gene causes inherited glycosylphosphatidylinositol deficiency2006
- Author(s)
  Yoshiko, Murakami, Antonio, Almeida, Mark, Layton, Peter, Hillmen, Yusuke, Maeda, Anastasios, Karadimitris, Taroh Kinoshita
- Organizer
  20th IUBMB International Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591060
[Presentation] 先天性GPI欠損症：知的障害・てんかんを呈する新しい疾患
- Author(s)
  村上良子
- Organizer
  第118回日本小児科学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-04-17 – 2015-04-19
- Invited
- Data Source
  KAKENHI-PUBLICLY-25129705
[Presentation] 先天性GPI欠損症：てんかん・知的障害を主症状とする新しい疾患
- Author(s)
  村上良子
- Organizer
  第57回日本小児神経学会学術集会
- Place of Presentation
  帝国ホテル　大阪
- Year and Date
  2015-05-28 – 2015-05-30
- Invited
- Data Source
  KAKENHI-PUBLICLY-25129705
[Presentation] 先天性GPI欠損症について
- Author(s)
  村上良子
- Organizer
  第51回補体シンポジウム
- Place of Presentation
  神戸常磐大学
- Year and Date
  2014-08-22 – 2014-08-23
- Data Source
  KAKENHI-PUBLICLY-25129705
[Presentation] 先天性GPI欠損症―てんかん・発達障害を主症状とする新たな疾患概念の確立―
- Author(s)
  村上良子
- Organizer
  第７８回大阪小児神経懇話会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] GPIアンカー型蛋白質構造異常を原因とする先天性GPI欠損症-PGAP1欠損症とPGAP3欠損症
- Author(s)
  村上良子
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PUBLICLY-25129705
[Presentation] GPIアンカー型タンパク質の構造異常を原因とする先天性GPI欠損症-PGAP1欠損症とPGAP3欠損症-
- Author(s)
  村上良子
- Organizer
  第56回日本小児神経学会学術集会
- Place of Presentation
  アクトシティー浜松
- Year and Date
  2014-05-28 – 2014-05-31
- Data Source
  KAKENHI-PUBLICLY-25129705
[Presentation] 先天性GPI欠損症ｰてんかん・発達障害を主症状とする新たな疾患-
- Author(s)
  村上良子
- Organizer
  第６０回関西ディスモルフォロジー研究会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23590363
[Presentation] 先天性GPI欠損症―てんかん・発達障害を主症状とする新たな疾患概念の確立―
- Author(s)
  村上良子
- Organizer
  第１７回大阪小児骨系統疾患研究会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23590363

1. KINOSHITA Taroh (10153165)

# of Collaborated Projects: 10 results

# of Collaborated Products: 64 results
2. MAEDA Yusuke (00294124)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
3. MORITA Yasuhiro (70397769)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. NAGAMUNE Kisaburo (90314418)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OHISHI Kazuhito (60273702)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. INOUE Norimitsu (80252708)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. FUJITA Morihisa (30532056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. Nishimura Junichi (80464246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. KOJI TOMINAGA (20599245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. TANIGAWA JUNPEI (40768636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 芦田久 (40379087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 青天目信 (30570072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 岩谷祥子 (60724903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. TANAKA Kiyoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 松本直通

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
16. 小池正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 城所博之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MURAKAMI YOSHIKO 村上 良子

村上 良子 ムラカミ ヨシコ

MURAKAMI Yoshiko 村上 良子

Research Projects

Research Products

Co-Researchers

GPI生合成と脂質合成に関わるARV1の機能の解明Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Mechanisms for regulation of glycosylphosphatidylinositol biosynthesis

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Analysos of metabolic abnormality which causes clonal expansion in Paroxysmal nocturnal hemoglobinuriaPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Devlopment of diagnostic marker and new treatment for inherited glycosylphosphatidylinositol anchored protein deficiency

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

先天性GPI欠損症の疾患概念の確立と発症機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis for the molecular mechanism of Inheited GPI DeficiencyPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Molecular mechanisms and functions of structural changes of protein GPI-anchors

Principal Investigator

Project Period (FY)

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Research Institution

Investigation of the mechanism for clonal expansion of GPI negative cells in paroxysmal nocturnal hemoglobinuriaPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

The regulation of functions and expressions of proteins by glycosylphosphatidylinositol-anchor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation into the mechanism for expansion of abnormal clone in paroxysmal nocturnal hemoglobinuriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

GPIアンカー合成の調節機構と合成不全症

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Biosynthesis pathway of GPI anchored proteins.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of biosynthesis of protein GPI anchors.

Principal Investigator

MURAKAMI YOSHIKO 村上良子

村上良子ムラカミヨシコ

MURAKAMI Yoshiko 村上良子

[Book] 先天性GPI欠損症分子細胞治療 vol.7 no.12008

[Book] 発作性夜間血色素尿症を代表とするGPI病、実験医学増刊糖鎖研究 vol.25 No.72007

[Book] 実験医学糖鎖研究発作性夜間血色素尿症を代表とするGPI病2007