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KIYOMOTO Hideyasu  清元 秀泰

ORCIDConnect your ORCID iD *help
Researcher Number 00304585
Affiliation (based on the past Project Information) *help 2018: 東北大学, 東北メディカル・メガバンク機構, 客員教授
2016 – 2017: 東北大学, 東北メディカル・メガバンク機構, 非常勤講師
2015: 東北大学, メディカルメガバンク機構, 教授
2014 – 2015: 東北大学, 学内共同利用施設等, 教授
2011 – 2014: 東北大学, 東北メディカル・メガバンク機構, 教授 … More
2010: 東北大学, 大学院・医学系研究科, 准教授
2005 – 2009: 香川大学, 医学部附属病院, 講師
2003 – 2004: 香川大学, 医学部, 助手
1999 – 2000: KAGAWA MEDICAL UNIVERSITY, ASSISTANT PROFESSOR, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Kidney internal medicine / Basic Section 53040:Nephrology-related / Kidney internal medicine
Except Principal Investigator
Kidney internal medicine / Rehabilitation science/Welfare engineering / 内科学一般 / Urology / General pharmacology
Keywords
Principal Investigator
ポドサイト / 酸化ストレス / 慢性腎不全 / 質量分析 / 物質輸送 / 細胞培養 / スリット膜 / 細胞間隙 / Podocin / Nephrin … More / ER4G / VEGF / 抗Thy1.1腎炎 / ER4G / VEGF / 内皮細胞 / PAI-1阻害薬 / 慢性糸球体腎炎 / クロピドグレル / mRNA / マクロファージ / LRP / MCP-1 / PAI-1 / PAI-1阻害薬 / 内皮障害 / 血栓性微小血管炎 / 糸球体腎炎 / NADPHオキシダーゼ / 稀少糖 / アポトーシス / NADPHオキシターゼ / 腹膜透析 / D-プシコース / 希少糖 / 腹膜中皮細胞 / NDA(P)Hオキシダーゼ / RT-PCR / TBARS / p22phox / 血液透析 / 腎不全 / 透析 / 遺伝子発現 / 白血球 / NAD(P)Hオキシダーゼ / 組織内伝播速度 / IgA腎症 / 組織内伝播速度(音速) / 抗Thy1腎炎 / OLETFラット / 実験腎炎 / 超音波顕微鏡 … More
Except Principal Investigator
酸化ストレス / isoprostane / 腎臓 / PTCA / 腎障害 / 高齢化社会 / 一酸化窒素 / 心臓 / 健康寿命延長 / 心・腎保護効果 / 長期的有酸素運動 / 抗加齢効果 / リハビリテーション / 運動療法 / phosphodiesterase / hemodialysis / renal failure / glomerulosclerosis / Isoprostane / phosphodiesterase (PDE) / 血液透析 / 腎不全 / 糸球体硬化 / REPERFUSION INJURY / MYOCARDIAL INFACTION / GENE TRANSFER / INTRACELLULAR SIGNAL TRANSDUCTION / ATHEROSCLEROSIS / OXIDANT STRESS / ISOPROSTANE / Reperfusioninjury / 心筋梗塞 / 遺伝子導入 / 細胞内情報伝達機構 / 動脈硬化 / 国際研究者交流、USA / 腎臓病 / 尿毒症物質 / マウス腎移植実験 / 慢性腎臓病 / 腎移植実験 / 尿毒症性物質 / 血液浄化 / カルボニルストレス / ナトリウム再吸収 / ヘンレのループ太い上行脚 / 腎臓髄質血流 / 虚血再灌流 / 低酸素 / グルコース / アンジオテンシンII / 蛍光イメージング / ミトコンドリア / 循環器・高血圧 / 薬理学 / 糖尿病性腎症 / ミネラロコルチコイド受容体 / アルドステロン Less
  • Research Projects

    (11 results)
  • Research Products

    (86 results)
  • Co-Researchers

    (23 People)
  •  透過型腎細胞培養系を用いた代謝変性物解析と尿中疾患バイオマーカーの探索Principal Investigator

    • Principal Investigator
      清元 秀泰
    • Project Period (FY)
      2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Tohoku University
  •  The mechanisms of anti-aging effects by chronic exercise

    • Principal Investigator
      Ito Daisuke
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Tohoku University
  •  The development of a novel therapeutic strategies for chronic kidney disease by the targeting on the renal mitochondrial oxidative stress.

    • Principal Investigator
      MORI TAKEFUMI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tohoku University
  •  A new therapy for blood purification of oxidative stress and uremic toxin verified by mouse kidney transplantation

    • Principal Investigator
      Abe Michiaki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Tohoku University
  •  The elucidation of interaction between glomerular podocyte and endothelium in glomerular injuryPrincipal Investigator

    • Principal Investigator
      KIYOMOTO hideyasu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tohoku University
  •  The development for new peritoneal dialysate to reduce oxidative stress and apoptosis using rare sugarPrincipal Investigator

    • Principal Investigator
      KIYOMOTO Hideyasu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tohoku University
      Kagawa University
  •  Mechanisms responsible for mineralocorticoid receptor-dependent renal injury

    • Principal Investigator
      NISHIYAMA Akira
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kagawa University
  •  The role of oxidative stress induced by NAD(P)H oxidase of leukocyte on cardiovascular damages in chronic kidney diseasePrincipal Investigator

    • Principal Investigator
      KIYOMOTO Hideyasu
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Kagawa University
  •  Prevention of glomerulosclerosis through the regulation of isoprostane pathway

    • Principal Investigator
      YUASA Shigekazu
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Kagawa Prefctural College of Health Sciences
      Kagawa Prefectural College of Health science
  •  透過型超音波顕微鏡を用いた腎組織病変定量の試みPrincipal Investigator

    • Principal Investigator
      清元 秀泰
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Kidney internal medicine
    • Research Institution
      香川医科大学
  •  ROLE OF OXIDANT STRESS IN THE PROGRESSION OF ATHEROSCLEROSIS AND THE DEVELOPMENT OF A WAY TO REGULATE ITS PROGRESSION

    • Principal Investigator
      FUKUNAGA Megumu
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      KAGAWA MEDICAL UNIVERSITY
      Osaka University

All 2015 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book

  • [Book] 『3.11から学んだ医療現場の脆弱生と想定外対応能力』;東日本大震災を分析する2 震災と人間・まち・記録,初版,[編纂]平川 新・今村 文彦2013

    • Author(s)
      阿部倫明,清元秀泰
    • Publisher
      明石書店
    • Data Source
      KAKENHI-PROJECT-25462533
  • [Book] Oxidative Stress in Basic Research and Clinical Practice Studies on Renal Disorders2011

    • Author(s)
      Kiyomoto H, et.al.
    • Publisher
      Renin angiotensin system in the kidney and oxidative stress -Local Renin Angiotensin Aldosterone System (RAAS) and NAD(P)H oxidase-dependent oxidative stress in the kidney-.
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Book] Chapter 4. Oxidative Stress in Basic Research and Clinical Practice : Renal Disorders(Miyata T, Eckardt KU, Nangaku M ed., Series Ed. : Armstrong D)(Springer, Humana Press, New York)2011

    • Author(s)
      Kiyomoto H, Kobori H, Nishiyama A
    • Publisher
      Renin angiotensin system in the kidney and oxidative stress-Local Renin Angiotensin Aldosterone System (RAAS) and NAD(P)H oxidase-dependent oxidative stress in the kidney-
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Book] Studies on Renal Disorders2011

    • Author(s)
      Kiyomoto H, 他
    • Publisher
      Oxidative stress in applied basic research and clinical practice
    • Data Source
      KAKENHI-PROJECT-20590253
  • [Book] Studies On Renal Disorders.2011

    • Author(s)
      Kiyomoto H, et.al
    • Total Pages
      800
    • Publisher
      Oxidative stress in applied basic research and clinical practice
    • Data Source
      KAKENHI-PROJECT-20590253
  • [Book] Renin angiotensin system in the kidney and oxidative stress-Local Renin Angiotensin Aldosterone System (RAAS)and NAD(P)H oxidase-dependent oxidative stress in the kidney-. Oxidative Stress in Basic Research and Clinical Practice : Renal Disorders2010

    • Author(s)
      Kiyomoto H, Kobori H, Nishiyama A.
    • Publisher
      Springer, Humana Press, Swiss
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Journal Article] Prominent hyperplasia of renin-producing juxtaglomerular apparatus after chronic and complete blockade of the renin-angiotensin system in adult IgA nephropathy2015

    • Author(s)
      Abe M, Joh K, Ieiri N, Hotta O, Utsunomiya Y, Sato H, Kisu K, Sakumo N, Kiyomoto H, Sato T, Taguma Y, Ito S
    • Journal Title

      CEN Case Rep

      Volume: 4 Issue: 2 Pages: 228-232

    • DOI

      10.1007/s13730-015-0177-y

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460449, KAKENHI-PROJECT-25462533
  • [Journal Article] Rare variant discovery by deep whole-genome sequencing of 1070 Japanese Individuals2015

    • Author(s)
      Nagasaki M, Yasuda J, Katsuoka F, Nariai N, Kojima K, Kawai Y, Yamaguchi-Kabata Y, Yokozawa J, Danjoh I, Saito S, Sato Y, Mimori T, Tsuda K, Saito R, Pan X, Nishikawa S, Ito S, Kuroki Y, Tanabe O, Fuse N, Kuriyama S, Kiyomoto H, Hozawa A, Minegishi N, Engel J D, Kinoshita K, Kure S, Yaegashi N, Yamamoto M.
    • Journal Title

      Nature Communications

      Volume: 6 Issue: 1 Pages: 8018-8018

    • DOI

      10.1038/ncomms9018

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09464, KAKENHI-PROJECT-25440254, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-25462533, KAKENHI-PROJECT-26240044
  • [Journal Article] A rare case among hypertensive patients: how do we handle reninomas?2013

    • Author(s)
      Okuda H, Abe M, Kiyomoto H.
    • Journal Title

      Intern Med.

      Volume: 52 Pages: 1853-1853

    • NAID

      130003365800

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462533
  • [Journal Article] A rare case among hypertensive patients: how do we handle reninomas?2013

    • Author(s)
      Okuda H, Abe M, Kiyomoto H.
    • Journal Title

      Intern Med

      Volume: 52(17) Pages: 1853-1853

    • NAID

      130003365800

    • Data Source
      KAKENHI-PROJECT-24591187
  • [Journal Article] Beneficial Role of Tolvaptan in the Control of Body Fluids Without Reductions in Residual Renal Function in Patients Undergoing Peritoneal Dialysis.2013

    • Author(s)
      Takefumi Mori, Ikuko Oba, Kenji Koizumi, Mayumi Kodama, Miwako Shimanuki, Mizuho Tanno, Makiko Chida, Mai Saito, Hideyasu Kiyomoto, Mariko Miyazaki, Susumu Ogawa, Hiroshi Sato, Sadayoshi Ito
    • Journal Title

      Advances in Peritoneal Dialysis

      Volume: 29 Pages: 33-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293193
  • [Journal Article] A small molecule inhibitor to plasminogen activator inhibitor 1 inhibits macrophage migration.2013

    • Author(s)
      Ichimura A1, Matsumoto S, Suzuki S, Dan T, Yamaki S, Sato Y, Kiyomoto H, Ishii N, Okada K, Matsuo O, Hou FF, Vaughan DE, van Ypersele de Strihou C, Miyata T.
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 33(5) Pages: 935-942

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591187
  • [Journal Article] Beneficial role of tolvaptan in the control of body fluids without reductions in residual renal function in patients undergoing peritoneal dialysis.2013

    • Author(s)
      Mori T, Oba I, Koizumi K, Kodama M, Shimanuki M, Tanno M, Chida M, Saito M, Kiyomoto H, Miyazaki M, Ogawa S, Sato H, Ito S.
    • Journal Title

      Adv Perit Dial

      Volume: 29 Pages: 33-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591187
  • [Journal Article] Plasticity of renal erythropoietin-producing cells governs fibrosis2013

    • Author(s)
      Souma T, Yamazaki S, Moriguchi T, Suzuki N, Hirano I, Pan X, Minegishi N, Abe M, Kiyomoto H, Ito S, Yamamoto M
    • Journal Title

      J Am Soc Nephrol

      Volume: 24 Issue: 10 Pages: 1599-1616

    • DOI

      10.1681/asn.2013010030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-24116502, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24591187, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-25462533, KAKENHI-PROJECT-25670157
  • [Journal Article] Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats2012

    • Author(s)
      Sofue T, Kiyomoto H, Kobori H, Urushihara M, Nishijima Y, Kaifu K, Hara T, Matsumoto S, Ichimura A, Ohsaki H, Hitomi H, Kawachi H, Hayden MR, Whaley-Connell A, Sowers JR, Ito S, Kohno M, Nishiyama A.
    • Journal Title

      Am J Hypertens

      Volume: 25(5) Pages: 604-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Journal Article] Chronic blockade of the (pro)renin receptor ameliorates the kidney damages in non-clipped kidney of Goldblatt hypertension.2011

    • Author(s)
      Kiyomoto H, Moriwaki K
    • Journal Title

      Hypertens Res.

      Volume: 34 Pages: 289-291

    • NAID

      10031163168

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Journal Article] New era for drug discovery and development in renal disease2011

    • Author(s)
      Miyata T, Kikuchi K, Kiyomoto H, van Ypersele de Strihou C
    • Journal Title

      Nature Review Nephrology

      Volume: 7 Pages: 469-477

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Journal Article] Angiotensin II shifts insulin signaling into vascular remodeling from glucose metabolism in vascular smooth muscle cells2011

    • Author(s)
      Hitomi H, Kaifu K, Fujita Y, Sofue T, Nakano D, Moriwaki K, Hara T, Kiyomoto H, Kohno M, Kobori H, Nishiyama A.
    • Journal Title

      Am J Hypertens

      Volume: 24(10) Pages: 1149-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Journal Article] Chronic block-ade of the (pro)renin receptor amelio-rates the kidney damages in non-clipped kidney of Goldblatt hypertension2011

    • Author(s)
      Kiyomoto H, Moriwaki K
    • Journal Title

      Hypertens Res

      Volume: 34 Pages: 289-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Journal Article] Chronic blockade of the (pro)renin receptor ameliorates the kidney damages in non-clipped kidney of Goldblatt hypertension2011

    • Author(s)
      Kiyomoto H, Moriwaki K
    • Journal Title

      Hypertens Res.

      Volume: 32 Issue: 11 Pages: 289-291

    • DOI

      10.1097/hjh.0b013e32833dfcda

    • NAID

      10031163168

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Journal Article] Involvement of mineralocorticoid receptor in high glucose-induced big mitogen-activated protein kinase 1 activation and mesangial cell proliferation2010

    • Author(s)
      Liu G, Miyata K, Hitomi H, Yao L, Sun GP, Suzaki Y, Hosomi N, Kiyomoto H, Nakano D, Tamaki T, Yoshizumi M, Nishiyama A.
    • Journal Title

      J Hypertens

      Volume: 28(3) Pages: 536-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Journal Article] Regression of superficial glomerular podocyte injury in type 2 diabetic rats with overt albuminuria : effect of angiotensin II blockade2010

    • Author(s)
      Ihara G、Kiyomoto H、Kobori H
    • Journal Title

      J.Hypertens Vol.28(最後掲載)

      Pages: 2289-2298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590253
  • [Journal Article] Insulin attenuates apoptosis induced by high glucose via the PI3-kinase/Akt pathway in rat peritoneal mesothelial cells2010

    • Author(s)
      Kaifu K, Kiyomoto H, Hitomi H, Matsubara K, Hara T, Moriwaki K, Ihara G, Fujita Y, Sugasawa S, Nagata D, Nishiyama A, Kohno M.
    • Journal Title

      Nephrol Dial Transplant

      Volume: 24(3) Pages: 809-815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Journal Article] 急性腎障害(AKI)の診療.保存的治療(薬物療法などを含む)2010

    • Author(s)
      清元秀泰、森脇久美子
    • Journal Title

      Modern Physician

      Volume: 31 Pages: 95-99

    • Data Source
      KAKENHI-PROJECT-21591055
  • [Journal Article] 急性腎障害(AKI)の診療. 保存的治療(薬物療法などを含む)2010

    • Author(s)
      清元秀泰、森脇久美子
    • Journal Title

      Modern Physician

      Volume: 31 Pages: 95-99

    • Data Source
      KAKENHI-PROJECT-21591055
  • [Journal Article] Regression ofsuperficial glomerular podocyte injury in type 2 diabetic rats with overt albuminuria : effect of angiotensin II blockade2010

    • Author(s)
      Ihara G, Kiyomoto H, Kobori H, Nagai Y, Ohashi N, Hitomi H, Nakano D, Pelisch N, Hara T, Mori T, Ito S, Kohno M, Nishiyama A.
    • Journal Title

      J Hypertens

      Volume: 28 Pages: 2289-98

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Journal Article] Regression of superficial glomerular podocyte injury in type 2 diabetic rats with overt albuminuria : effect of angiotensin II blockade.2010

    • Author(s)
      Ihara C, Kiyomoto H, et.al.
    • Journal Title

      J Hypertens.

      Volume: 28 Pages: 2289-98

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Journal Article] Insulin attenuates apoptosis induced by high glucose via thePl_3-kinase/Akt pathway in rat peritoneal mesothelial cells.2009

    • Author(s)
      Kaifu K, Kiyomoto H., et. al.
    • Journal Title

      Nephrol Dial Transplant 24(3)

      Pages: 809-815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Insulin attenuates apoptosis induced by high glucose via the PI3-kinase/Akt pathway in rat peritoneal mesothelial cells2009

    • Author(s)
      Kaifu K, Kiyomoto H, Hitomi H, Matsubara K, Hara T, Moriwaki K, Ihara G, Fujita Y, Sugasawa S, Nagata D, Nishiyama A, Kohno M.
    • Journal Title

      Nephrol Dial Transplant 24(3)

      Pages: 809-815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Insulin attenuates apoptosis induced by high glucose via the PI_3-kinase/Akt pathway in rat peritoneal mesothelial cells2009

    • Author(s)
      Kiyomoto H, 他9名
    • Journal Title

      Nephrol Dial Transplant 24(3)

      Pages: 809-815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Journal Article] Possible involvement of Rho-kinase in aldosterone-induced vascular remodeling.2008

    • Author(s)
      Kiyomoto H, et al.
    • Journal Title

      J. Pharmacol. Sci. 108

      Pages: 399-405

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590253
  • [Journal Article] 泌尿器/腎慢性腎臓病2008

    • Author(s)
      清元秀泰, 森脇久美子
    • Journal Title

      治療 90

      Pages: 94-95

    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] CKDマネイジメント 造影剤による腎障害2008

    • Author(s)
      松原啓介、清元秀泰
    • Journal Title

      Modern Physician 28

      Pages: 1229-1233

    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Do vasculature reactive oxygen species play a role in the mobilization of bone marrow endothelial progenitor cells?2008

    • Author(s)
      Kiyomoto H, Nishiyama A.
    • Journal Title

      J. Hypertens. 26

      Pages: 188-190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590253
  • [Journal Article] ARBとCCBによる尿細管間質障害治療2008

    • Author(s)
      西山成、清元秀泰
    • Journal Title

      医学のあゆみ 225(4)

      Pages: 321-325

    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Do vasculature reactive oxygen species play a role in the mobilization of bone marrow endothelial progenitor cells?2008

    • Author(s)
      Kiyomoto H, Nishiyama A
    • Journal Title

      J Hypertens 26

      Pages: 188-190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] CKDマネイジメント 造影剤による腎障害.2008

    • Author(s)
      松原啓介, 清元秀泰
    • Journal Title

      Modern Physician 28

      Pages: 1229-1233

    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] 腎障害を有する高血圧の治療2007

    • Author(s)
      清元秀泰
    • Journal Title

      日本内科学会雑誌 96(1)

      Pages: 65-72

    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Angiotensin II and oxidative stress2007

    • Author(s)
      Hitomi H, Kiyomoto H, Nishiyama A
    • Journal Title

      Curr Opin Cardiol 22(4)

      Pages: 311-315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] 慢性腎臓病(CKD)の治療および予防における戦略2007

    • Author(s)
      河野雅和、秋山賢次、伊原玄英、鬼無 信、清元秀泰、小路哲生、高橋則尋、濱本龍七郎、藤岡宏、村尾孝児
    • Journal Title

      Progress in Medicine 27(6)

      Pages: 1355-1364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Aldosterone suppresses insulin signaling via the downregulation of insulin receptor substrate-1 in vascular smooth muscle cells.2007

    • Author(s)
      Hitomi H, Kiyomoto H, Nishiyama A, et. al.
    • Journal Title

      Hypertension 50(4)

      Pages: 750-755

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] The earlier,the better.2007

    • Author(s)
      Kiyomoto H, Hitomi H
    • Journal Title

      Hypertens Res 30

      Pages: 1-2

    • NAID

      10018831209

    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] 腎障害を有する高血圧の治療.2007

    • Author(s)
      清元 秀泰
    • Journal Title

      日本内科学会雑誌 96(1)

      Pages: 65-72

    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] The earlier, the better2007

    • Author(s)
      Kiyomoto H, Hitomi H
    • Journal Title

      Hypertens Res 30

      Pages: 1-2

    • NAID

      10018831209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Angiotensin II and oxidative stress.2007

    • Author(s)
      Hitomi H, Kiyomoto H, Nishiyama A.
    • Journal Title

      Curr Opin Cardiol 22(4)

      Pages: 311-315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] 腎不全合併難治性腹水患者に対する腹水濾過還元血液透析療法(AFRHD)の有用性2006

    • Author(s)
      清元秀泰、東山智香子
    • Journal Title

      日本アフェレシス学会雑誌 25(2)

      Pages: 125-131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Synergistic effect of mechanical stretch and angiotensin II on superoxide production via NADPH oxidase in vascular smooth muscle cells2006

    • Author(s)
      Hitomi H, Fukui T, Moriwaki K, Matsubara K, Sun GP, Rahman M, Nishiyama A, Kiyomoto H, Kimura S, Ohmori K, Abe Y, Kohno M
    • Journal Title

      J Hypertens 24

      Pages: 1089-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] 腎不全の診断と治療(2)~慢性腎不全の治療~2006

    • Author(s)
      原大雅、清元秀泰
    • Journal Title

      医薬ジャーナル 41(3)

      Pages: 1056-1061

    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Interferon-gamma enhances superoxide production in human mesangial cells via the JAK-STAT pathway.2006

    • Author(s)
      Moriwaki K, Kiyomoto H, Hitomi H, Hara T, Ohmori K, Nishiyama A, et al.
    • Journal Title

      Kidney Int. 70(4)

      Pages: 788-793

    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] 腎不全の診断と治療~急性腎不全の鑑別と治療方針~2006

    • Author(s)
      海部久美子、清元秀泰
    • Journal Title

      医薬ジャーナル 41(2)

      Pages: 773-778

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] 腎障害進展におけるアルドステロン/ミネラロコルチコイド受容体と酸化ストレスの役割2006

    • Author(s)
      西山成、今西政仁、清元秀泰、河野雅和、安部陽一
    • Journal Title

      臨床薬理の進歩 27

      Pages: 139-144

    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] アルドステロン依存性腎障害における酸化ストレス、MAPキナーゼ、Rhoキナーゼの役割2006

    • Author(s)
      人見浩史、清元秀泰、河野雅和、西山成
    • Journal Title

      内分泌・糖尿病科 23(6)

      Pages: 575-580

    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Interferon-γ enhances superoxide production in human mesangial cells via the JAK-STAT pathway2006

    • Author(s)
      Moriwaki K, Kiyomoto H, Hitomi H, Ihara G, Kaifu K, Matsubara K, Hara T, Kondo N, Ohmori K, Nishiyama A, Fukui T, Kohno M
    • Journal Title

      Kidney Int 70(4)

      Pages: 788-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Effects of calcium channel blockade on angiotensin II-induced peritubular ischemia in rats.2006

    • Author(s)
      Kondo N, Kiyomoto H, Hitomi H, Moriwaki K, Hra T, Abe Y, Kohno M, Nishiyama A, et al.
    • Journal Title

      J Pharmacol Exp Ther. 316(3)

      Pages: 1047-1052

    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Reduction of oxidized low-density lipoprotein by the long-term use of vitamin E-coated dialyzers in hemodialysis patients2005

    • Author(s)
      Hara T, Takahashi N, Kiyomoto H, Moriwaki K, Fujioka H, Matsubara K, Kondo N, Shokoji T, Kiyomoto K, Hirohata M, Ishizu T, Akiyama K, Nishiyama A, Ohmori K, Kohno M
    • Journal Title

      Dialysis & Transplantation 33(4)

      Pages: 197-202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] 腎不全および維持血液透析における酸化ストレスの評価とその対策に関する研究2005

    • Author(s)
      東山智香子、清元秀泰、西山成、今西政仁、河野雅和
    • Journal Title

      腎臓 27(2)

      Pages: 105-109

    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Effective LDL apheresis in a case of peripheral circulatory insufficiency in the forearm from repeated internal arteriovenous fistula surgeries2005

    • Author(s)
      Hara T, Kiyomoto T, Moriwaki K, Higashiyama, Matsubara K, Hitomi H, Kondo N, Kaifu K, Ihara K, Ohmori K, Kohno M.
    • Journal Title

      日本アフェレシス学会雑誌 25(1)

      Pages: 52-56

    • NAID

      110004028299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Aldosterone Stimulates Reactive Oxygen Species Production through Activation of NADPH Oxidase in Rat Mesangial Cells2005

    • Author(s)
      Miyata K, Rahman M, Shokoji T, Nagai Y, Zhang GX, Sun GP, Kimura S, Yukimura T, Kiyomoto H, Kohno M, Abe Y, Nishiyama A
    • Journal Title

      J Am Soc Nephrol 16(10)

      Pages: 2906-2912

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Journal Article] Effects of local administrations of tempol and diethyldithio-carbamic on peripheral nerve activity2004

    • Author(s)
      Shokoji T, Kiyomoto H, et al.
    • Journal Title

      Hypertension 44(2)

      Pages: 236-243

    • Data Source
      KAKENHI-PROJECT-15590873
  • [Journal Article] Effects of AT1 receptor blockade on renal injury and mitogen-activated protein kinase activity in Dahl salt-sensitive rats.2004

    • Author(s)
      Nishiyama A, Kiyomoto H, et al.
    • Journal Title

      Kidney Int 65

      Pages: 972-981

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590873
  • [Journal Article] Effect of AT1 receptor blockade on renal injury and mitogen-activated protein kinase activity in Dahl salt-sensitive rats.2004

    • Author(s)
      Nishiyama A, Kiyomoto H, et al.
    • Journal Title

      Kidney Int 65

      Pages: 972-981

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590873
  • [Journal Article] Effects of AT1 receptor blockade on renal injury and mitogen-activated protein kinase activity in Dahl salt-sensitive rats.2004

    • Author(s)
      Nishiyama A, Kiyomoto H, et al.
    • Journal Title

      Kideny Int 65(3)

      Pages: 972-981

    • Data Source
      KAKENHI-PROJECT-15590873
  • [Journal Article] The SOD mimetic tempol ameliorates glomerular injury and reduces mitogen-activated protein kinase activity in Dahl salt-sensitive rats.2004

    • Author(s)
      Nishiyama A, Fukunaga M, Kiyomoto H, et al.
    • Journal Title

      J Am Soc Nephrol 15(2)

      Pages: 306-315

    • Data Source
      KAKENHI-PROJECT-15590873
  • [Journal Article] Effect of interferon-γ on generating superoxide anion through the NADPH oxidase in cultured human mesangial cells.2003

    • Author(s)
      Kiyomoto H, et al.
    • Journal Title

      J Am Soc Nephrol 14

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590873
  • [Journal Article] Effect of interferon-γ on generating superoxide anion through the NADPH oxidase in cultured human mesangial cells.2003

    • Author(s)
      Kiyomoto H, et al.
    • Journal Title

      J Am Sac Nephral 14

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590873
  • [Presentation] Pharmacological inhibition of plasminogen activator inhibitor (PAI)-1 ameliorates glomerular podocyte injury in anti-Thy1.1 glomerulonephritis.2012

    • Author(s)
      Hideyasu Kiyomoto, MD, PhD, Kumiko Moriwaki, MD, PhD, et al.
    • Organizer
      American Society of Nephrology 2012
    • Place of Presentation
      San Diego, California,USA
    • Data Source
      KAKENHI-PROJECT-24591187
  • [Presentation] The remedial effect of strict diet treatment and exercise therapy using information technology (IT)on metabolic syndrome2010

    • Author(s)
      Kiyomoto H, et. al
    • Organizer
      43rd Annual meeting of American Society of Nephrology, Renal Week.
    • Place of Presentation
      Denver, CO, USA
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Presentation] The remedial effect of strict diet treatment and exercise therapy using information technology (IT) on metabolic syndrome.2010

    • Author(s)
      Kiyomoto H, et.al.
    • Organizer
      43^<rd> Annual meeting of American Society of Nephrology, Renal Week
    • Place of Presentation
      Denver, CO, USA
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Presentation] Psicose containing solution suppresses glucose-induced reactive oxygen species (ROS) dependent epithelial to mesenchymal transition (EMT) in cultured rat peritoneal mesothelial cells2009

    • Author(s)
      Kiyomoto H, 他
    • Organizer
      American Society of Nephrology (アメリカ腎臓学会)
    • Place of Presentation
      サンディエゴ国際コンベンションセンター (アメリカ)
    • Year and Date
      2009-11-03
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Presentation] Psicose containing solution suppresses glucose-induced reactive oxygen species (ROS)dependent epithelial to mesenchymal transition (EMT)in cultured rat peritoneal mesothelial cells2009

    • Author(s)
      Kiyomoto H, 他
    • Organizer
      American Society of Nephrology(アメリカ腎臓学会)
    • Place of Presentation
      サンディエゴ国際コンベンションセンター(アメリカ)
    • Year and Date
      2009-11-03
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Presentation] The inhibitory effect of rare sugars on epithelial-mesenchymal transition (EMT) induced by high concentration of D-glucose in cultured rat peritoneal mesothelial cells2009

    • Author(s)
      Kiyomoto H, 他
    • Organizer
      World Congress of Nephrology (国際腎臓会議)
    • Place of Presentation
      ミラノ国際コンベンションセンター (イタリア)
    • Year and Date
      2009-06-02
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Presentation] The inhibitory effect of rare sugars on epithelial-mesenchymal transition (EMT)induced by high concentration of D-glucose in cultured rat peritoneal mesothelial cells2009

    • Author(s)
      Kiyomoto H, 他
    • Organizer
      World Congress of Nephrology(国際腎臓会議)
    • Place of Presentation
      ミラノ国際コンベンションセンター(イタリア)
    • Year and Date
      2009-06-02
    • Data Source
      KAKENHI-PROJECT-21591055
  • [Presentation] 人工透析患者における抗β_1アドレナリン受容体抗体IgGサブクラス.2008

    • Author(s)
      馬場彰泰, 池田亜希子, 清元秀泰, 緒方浩顕
    • Organizer
      第29回日本アフェレシス学会学術大会
    • Place of Presentation
      広島
    • Year and Date
      2008-10-16
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Presentation] 人工透析患者における抗β1アドレナリン受容体抗体IgGサブクラス2008

    • Author(s)
      馬場彰泰、池田亜希子、清元秀泰、緒方浩顕
    • Organizer
      第29回日本アフェレシス学会学術大会
    • Place of Presentation
      広島
    • Year and Date
      2008-10-16
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Presentation] Immunoadsorption as a new treatment against autoimmune heart failure.Double-filtration plasmaphersis(DFPP)in cardiac dysfunction patients with advanced chronic renal disease (CKD).2007

    • Author(s)
      Kiyomoto H
    • Organizer
      6^<th>Wbrld Congress of the International Society for Apheresis, World Apheresis Association 11^<th> Congress
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Presentation] 高糖濃度が腹膜中皮細胞のNADPH oxidaseに及ぼす影響2007

    • Author(s)
      森脇久美子、清元秀泰、藤田昌子、伊原玄英、海部久美子、原大雅、人見浩史、祖父江理、鵜川豊世武、河野雅和
    • Organizer
      第52回日本透析医学会学術集会・総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-06-21
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Presentation] 腎不全合併末梢循環不全におけるLDLアフェレシス療法の有効性と白血球NADPH oxidaseの関与2007

    • Author(s)
      原大雅、清元秀泰、森脇久美子、西山成、近藤直樹、鵜川豊世武、人見浩史、松原啓介、伊原玄英、海部久美子、森諭史、東山智香子、岩崎憲泰、海部泰夫、岡本雅也、河野雅和
    • Organizer
      第27回日本アフェレシス学会学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-03-15
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Presentation] 酸化ストレスの評価方法と腎障害への応用酸化ストレスと腎障害2007

    • Author(s)
      西山成、清元秀泰、小堀浩幸、河野雅和
    • Organizer
      第50回日本腎臓学会学術総会
    • Place of Presentation
      浜松
    • Year and Date
      2007-06-08
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Presentation] Immunoadsorption as a new treatment against autoimmune heart failure Double filtration plasmaphersis (DFPP) in cardiac dysfunction patients with advanced chronic renal disease (CKD)2007

    • Author(s)
      Kiyomoto H
    • Organizer
      6^<th> World Congress of the International Society for Apheresis, World Apheresis Association 11^<th> Congress
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2007-03-14
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Presentation] IFN-γによるヒトメサンギウム細胞のスーパーオキサイド産生系の検討2006

    • Author(s)
      森脇久美子、清元秀泰、人見浩史、西山成、河野雅和
    • Organizer
      第6回日本NO学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2006-09-16
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Presentation] 腹膜中皮細胞における糖負荷による酸化ストレスとNADPH oxidaseの検討2006

    • Author(s)
      森脇久美子、清元秀泰、藤田昌子、伊原玄英、海部久美子、近藤直樹、原大雅、人見浩史、鵜川豊世武、河野雅和
    • Organizer
      第51回日本透析医学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2006-06-07
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Presentation] 末梢循環不全合併透析患者に対するLDLアフェレシス療法の有用性-LDLアフェレシス療法による酸化ストレス軽減について-2006

    • Author(s)
      原大雅、清元秀泰、森脇久美子、西山成、近藤直樹、鵜川豊世武、人見浩史、松原啓介、伊原玄英、海部久美子、森諭史、東山智香子、岩崎憲泰、海部泰夫、岡本雅也、河野雅和
    • Organizer
      第26回日本アフェレシス学会学術大会
    • Place of Presentation
      大津
    • Year and Date
      2006-09-26
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Presentation] 末梢循環不全合併透析患者に対するLDLアフェレシス療法の有用性-LDLアフェレシス療法による酸化ストレス軽減について-2005

    • Author(s)
      原大雅、清元秀泰、森脇久美子、近藤直樹、鵜川豊世武、人見浩史、松原啓介、伊原玄英、海部久美子、藤田昌子、西山成、森諭史、濱本有祐、佐野法久、東山智香子、松本恵子、森田順子、佐藤弘子、岩崎憲泰、小野茂男、海部泰夫、松本正義、嘉村智美、宮野恭匡
    • Organizer
      第25回日本アフェレシス学会学術大会
    • Place of Presentation
      奈良
    • Year and Date
      2005-10-20
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Presentation] 血液透析療法にける酸化ストレスと白血球NAD(P)H oxidase p22phox遺伝子発現に関する検討2005

    • Author(s)
      清元秀泰、森脇久美子、原大雅、伊原玄英、近藤直樹、松向寺孝臣、鵜川豊世武、松原啓介、人見浩史、西山成、河野雅和
    • Organizer
      第48回日本腎臓学会総会
    • Place of Presentation
      神奈川
    • Year and Date
      2005-06-04
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Presentation] 末梢循環不全合併透析患者に対するLDLアフェレシス療法の有用性2005

    • Author(s)
      原大雅、清元秀泰、森脇久美子、東山智香子、松本恵子、横山るみ子、佐藤弘子、岩崎泰憲、海部泰夫、宮野恭匡、近藤直樹、鵜川豊世武、松向寺孝臣、人見浩史、西山成、河野雅和
    • Organizer
      第50回日本透析医学会学術集会
    • Place of Presentation
      神奈川
    • Year and Date
      2005-06-07
    • Data Source
      KAKENHI-PROJECT-17590830
  • [Presentation] 血液透析療法における酸化ストレスの産生と白血球NAD(P)H oxidaseコンポーネントp22phox遺伝子発現に関する検討2005

    • Author(s)
      清元秀泰、森脇久美子、藤田昌子、マットルーブル・ラフマン、原大雅、近藤直樹、松向寺孝臣、鵜川豊世武、松原啓介、西山成、河野雅和
    • Organizer
      第5回腎不全病態治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2005-03-26
    • Data Source
      KAKENHI-PROJECT-17590830
  • 1.  FUKUNAGA Megumu (40283775)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  NISHIYAMA Akira (10325334)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 24 results
  • 3.  MORIWAKI Kumiko (90398040)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  MORI TAKEFUMI (40375001)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  ITO SADAYOSHI (40271613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  OHSAKI YUSUKE (40509212)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  Abe Michiaki (40400246)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  HORIO Masaru (20273633)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SENDA Shoichi (30145049)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ORITA Yoshimasa (70028398)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  YUASA Shigekazu (60174827)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  Ito Daisuke (50466570)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  原 大雅 (50398038)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 14.  佐藤 恵美子 (20466543)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  城 謙輔 (10057086)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  伊藤 修 (00361072)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  平良 摩紀子 (60792140)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  OKUDA HIROSHI
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  MIURS takahiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  hu GAIZUN
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SUZUKI Norio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  KATSUOKA Fumiki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  峯岸 直子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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