Iwao Noriaki 岩尾憲明

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IWAO NORIAKI 岩尾憲明

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Researcher Number	00309139
Affiliation (Current)	2025: 順天堂大学, 医学部, 先任准教授
Affiliation (based on the past Project Information) *help	2024: 順天堂大学, 医学部, 先任准教授 2015 – 2020: 順天堂大学, 医学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Hematology Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics / Respiratory organ internal medicine
Keywords	Principal Investigator 上皮間葉転換 / 大腸癌転移 / 抗CD26抗体 / DPPⅣ / 慢性GVHD / CD26 / 好酸球 / 好中球 / 炎症 / HMGB1 / GVHD … More Except Principal Investigator … More 線維化 / GVHD / 造血幹細胞移植 / IL-26 / 慢性GVHD / CD26 / 臓器線維症 / 肺線維症 / 小児血液学 / 移植免疫学 / DPP4 / caveolin-1 / Caveolin-1 / ソマトスタチン / dipeptydil peptidase 4 / CD26抗体療法 / ペリオスチン / ソマトスタチン受容体 / 悪性中皮腫 Less

ヒト化抗CD26抗体を用いた大腸癌の転移病巣に対する新規治療法の開発Principal Investigator
- Principal Investigator
  
  岩尾憲明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Juntendo University
Scientific research on development of anti-fibrotic agent targeting multi-organ profibrotic factor IL-26 in GVHD
- Principal Investigator
  
  Kei Ohnuma
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Juntendo University
Prevention of chronic GVHD onset by HMGB1 inhibiton of DPP4Principal Investigator
- Principal Investigator
  
  IWAO NORIAKI
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Juntendo University
Large molecular complex of cell surface in malignant pleural mesotheliom as a novel treatment target
- Principal Investigator
  
  OHNUMA Kei
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Mechanism of lung fibrosis in chronic GVHD
- Principal Investigator
  
  OHNUMA Kei
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Juntendo University

All 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] DPP8 is a novel therapeutic target for multiple myeloma.2019
- Author(s)
  Sato T, Tatekoshi A, Takada K, Iyama S, Kamihara Y, Jawaid P, Rehman MU, Noguchi K, Kondo T, Kajikawa S, Arita K, Wada A, Murakami J, Arai M, Yasuda I, Dang NH, Hatano R, Iwao N, Ohnuma K, Morimoto C.
- Journal Title
  
  Sci Rep
  
  Volume: 9 Issue: 1 Pages: 18094-18094
- DOI
  10.1038/s41598-019-54695-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02782, KAKENHI-PROJECT-17K10008
[Journal Article] GVHDと慢性炎症2019
- Author(s)
  岩尾憲明　大沼圭　大塚春奈　波多野良　古宮栄利子　伊藤匠　森本幾夫
- Journal Title
  
  別冊BioClinica
  
  Volume: 8 Pages: 128-133
- Data Source
  KAKENHI-PROJECT-16K09878
[Journal Article] A novel role for CD26/dipeptidyl peptidase IV as a therapeutic target2018
- Author(s)
  Ohnuma K, Hatano R, Komiya E, Otsuka H, Itoh T, Iwao N, Kaneko Y, Yamada T, Dang NH, Morimoto C.
- Journal Title
  
  Front Biosci
  
  Volume: 23 Issue: 9 Pages: 1754-1779
- DOI
  10.2741/4671
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02782
[Journal Article] Inhibition of VEGF-dependent angiogenesis by the anti-CD82 monoclonal antibody 4F9 through regulation of lipid raft microdomains2016
- Author(s)
  Nomura, S. Iwata, S. Hatano, R. Komiya, E. Dang, N. H. Iwao, N. Ohnuma, K. Morimoto, C.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 474 Issue: 1 Pages: 111-7
- DOI
  10.1016/j.bbrc.2016.04.081
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-26830114, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-14J12067
[Journal Article] Role of IL-26+CD26+CD4 T Cells in Pulmonary Chronic Graft-Versus-Host Disease and Treatment with Caveolin-1-Ig Fc Conjugate2016
- Author(s)
  Ohnuma, K. Hatano, R. Itoh, T. Iwao, N. Dang, N. H. Morimoto, C.
- Journal Title
  
  Crit Rev Immunol
  
  Volume: 36 Issue: 3 Pages: 239-267
- DOI
  10.1615/critrevimmunol.2016018772
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-14J12067
[Presentation] 急性GVHDマウスモデルにおけるHMGB1の動態に関する検討2018
- Author(s)
  岩尾憲明、大沼圭、大塚春奈、波多野良、古宮栄利子、伊藤匠、森本幾夫
- Organizer
  第40回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-16K09878
[Presentation] Interleukin-26-targeted therapy for the control of chronic GVHD2018
- Author(s)
  Hating R, Otsuka H, Komiya E, Itoh T, Iwao I, Yamada T, Morimoto C, Ohnuma K.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02782
[Presentation] 急性GVHDマウスモデルにおけるHMGB1の動態に関する検討2017
- Author(s)
  岩尾憲明、大沼圭、大塚春奈、波多野良、古宮栄利子、伊藤匠、森本幾夫
- Organizer
  日本造血幹細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-15H04879
[Presentation] Anti-interleukin-26 therapy for lung fibrosis of GVHD2015
- Author(s)
  Ryo Hatano, Taketo Yamada, Haruna Otsuka, Eriko Komiya, Noriaki Iwao, Ko Okumura, Chikao Morimoto, Kei Ohnuma
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢市
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15H04879

1. OHNUMA Kei (10396872)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
2. 岩田哲史 (00396871)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. 森本幾夫 (30119028)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. 波多野良 (30638789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Iwao Noriaki 岩尾 憲明

IWAO NORIAKI 岩尾 憲明

Research Projects

Research Products

Co-Researchers

ヒト化抗CD26抗体を用いた大腸癌の転移病巣に対する新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Scientific research on development of anti-fibrotic agent targeting multi-organ profibrotic factor IL-26 in GVHD

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Prevention of chronic GVHD onset by HMGB1 inhibiton of DPP4Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Large molecular complex of cell surface in malignant pleural mesotheliom as a novel treatment target

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of lung fibrosis in chronic GVHD

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] DPP8 is a novel therapeutic target for multiple myeloma.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GVHDと慢性炎症2019

Author(s)

Journal Title

Data Source

[Journal Article] A novel role for CD26/dipeptidyl peptidase IV as a therapeutic target2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of VEGF-dependent angiogenesis by the anti-CD82 monoclonal antibody 4F9 through regulation of lipid raft microdomains2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of IL-26+CD26+CD4 T Cells in Pulmonary Chronic Graft-Versus-Host Disease and Treatment with Caveolin-1-Ig Fc Conjugate2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] 急性GVHDマウスモデルにおけるHMGB1の動態に関する検討2018

Author(s)

Organizer

Data Source

[Presentation] Interleukin-26-targeted therapy for the control of chronic GVHD2018

Author(s)

Organizer

Data Source

[Presentation] 急性GVHDマウスモデルにおけるHMGB1の動態に関する検討2017

Author(s)

Organizer

Data Source

[Presentation] Anti-interleukin-26 therapy for lung fibrosis of GVHD2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Iwao Noriaki 岩尾憲明

IWAO NORIAKI 岩尾憲明