Miyazaki Kazuko 宮崎和子

… Alternative Names

MIYAZAKI Kazuko 宮崎和子

宮崎和子ミヤザキカズコ

中舛和子ナカマスカズコ

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Researcher Number	00311811
Other IDs
Affiliation (Current)	2025: 京都大学, 医生物学研究所, 研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 京都大学, 医生物学研究所, 研究員 2022: 京都大学, 医生物学研究所, 特定研究員 2021: 京都大学, ウイルス・再生医科学研究所, 特定研究員 2017 – 2019: 京都大学, ウイルス・再生医科学研究所, 研究員 2016: 京都大学, ウイルス・再生医科学研究所, 特定研究員 … More 2015: 京都大学, 再生医科学研究所, 研究員 2008 – 2010: 広島大学, 原爆放射線医科学研究所, 助教 2003 – 2006: 広島大学, 原爆放射線医科学研究所, 助手 1999 – 2000: 広島大学, 歯学部, 助手 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 48040:Medical biochemistry-related / Basic Section 54010:Hematology and medical oncology-related / Biological Sciences / Functional basic dentistry Except Principal Investigator Functional basic dentistry / Hematology
Keywords	Principal Investigator 転写因子 / 遺伝子 / ゲノム構造 / 遺伝子発現制御 / 転写制御 / 制御性T細胞 / 細胞・組織 / 低酸素 / 発現調節 / Treg細胞 … More / 3Dゲノム構造 / がん / ３Dゲノム構造 / E2A, Id2, Id3 / Treg / トランスジェニックマウス / 細胞分化 / T細胞 / 低酸系 / 転写活性 / 軟骨 / 遺伝子発現調節 / 軟骨細胞 / MTf / 膜結合型トランスフェリン様蛋白 … More Except Principal Investigator DEC1 / Indian hedgehog / retinoic adic / PTHrp / chondrocyte / ノックアウトマウス / レチノール結合タンパク / 軟骨細胞 / 副甲状腺ホルモン様ペプチド / 副甲状腺ホルモン / 分裂異常期 / エンドソーム代謝 / 分裂期異常 / 遺伝子欠損マウス / 発がん抑制遺伝子 / 7番染色体欠損 / 骨髄性白血病 / MDS Less

コヒーシンによるTreg細胞特異的なゲノム構造制御と組織炎症抑制の分子機構の解明Principal Investigator
- Principal Investigator
  
  宮崎和子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Kyoto University
Analysis of molecular mechanism involved in 3D genome structure in the progression of malignant lymphomaPrincipal Investigator
- Principal Investigator
  
  Miyazaki Kazuko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
Analyisis of regulome through E/Id protein axis in Treg cellsPrincipal Investigator
- Principal Investigator
  
  Kazuko Miyazaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Analysis of transcriptional regulation in Treg cells by Id-proteinPrincipal Investigator
- Principal Investigator
  
  Miyazaki Kazuko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
bHLH型転写因子Dec1による制御性T細胞の新規維持機構の解明Principal Investigator
- Principal Investigator
  
  宮崎和子
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hiroshima University
Functional analysis of candidate responsible genes for 7q deletion in MDS/AML
- Principal Investigator
  
  INABA Toshiya
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Hiroshima University
遺伝子導入マウスを用いたT細胞の機能制御と低酸素での転写因子DEC1の機能解析Principal Investigator
- Principal Investigator
  
  宮崎和子
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hiroshima University
新規転写因子DEC1の低酸素応答における機能解析Principal Investigator
- Principal Investigator
  
  宮崎和子
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
転写因子DEC1/2の低酸素応答における新規経路と機能解析Principal Investigator
- Principal Investigator
  
  宮崎和子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hiroshima University
膜結合型トランスフェリン様蛋白遺伝子の発現調節機構の解明Principal Investigator
- Principal Investigator
  
  中舛和子
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Role of PTH and PTH-related peptide in skeletal development
- Principal Investigator
  
  KATO Yukio
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University

All 2023 2022 2021 2017 2010 2009 2008 2005

All Journal Article Presentation

[Journal Article] Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow2023
- Author(s)
  Abe Shinya、Asahi Takuma、Hara Takahiro、Cui Guangwei、Shimba Akihiro、Tani-ichi Shizue、Yamada Kohei、Miyazaki Kazuko、Miyachi Hitoshi、Kitano Satsuki、Nakamura Naotoshi、Kikuta Junichi、Vandenbon Alexis、Miyazaki Masaki、Yamada Ryo、Ohteki Toshiaki、Ishii Masaru、Sexl Veronika、Nagasawa Takashi、Ikuta Koichi
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 9 Pages: 113127-113127
- DOI
  10.1016/j.celrep.2023.113127
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-21K08370, KAKENHI-PROJECT-22K19430, KAKENHI-PUBLICLY-22H05627, KAKENHI-PROJECT-23K24152, KAKENHI-PROJECT-23K27425, KAKENHI-PROJECT-23K27426
[Journal Article] The E-Id Axis Instructs Adaptive Versus Innate Lineage Cell Fate Choice and Instructs Regulatory T Cell Differentiation2022
- Author(s)
  Hidaka Reiko、Miyazaki Kazuko、Miyazaki Masaki
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 1-12
- DOI
  10.3389/fimmu.2022.890056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08370, KAKENHI-PROJECT-22K19430
[Journal Article] The Interplay Between Chromatin Architecture and Lineage-Specific Transcription Factors and the Regulation of Rag Gene Expression.2021
- Author(s)
  Miyazaki K., Miyazaki M.
- Journal Title
  
  Frontiers in Immunology,
  
  Volume: 12
- DOI
  10.3389/fimmu.2021.659761
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03487, KAKENHI-PROJECT-21K08370
[Journal Article] The Evolution of Rag Gene Enhancers and Transcription Factor E and Id proteins in the Adaptive Immune System.2021
- Author(s)
  Yoshikawa G, Miyazaki K, Ogata H*, Miyazaki M
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 11 Pages: 5888-5888
- DOI
  10.3390/ijms22115888
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03487, KAKENHI-PROJECT-21K08370
[Journal Article] The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development2017
- Author(s)
  Miyazaki Masaki、Miyazaki Kazuko、Chen Kenian、Jin Yi、Turner Jacob、Moore Amanda J.、Saito Rintaro、Yoshida Kenichi、Ogawa Seishi、Rodewald Hans-Reimer、Lin Yin C.、Kawamoto Hiroshi、Murre Cornelis
- Journal Title
  
  Immunity
  
  Volume: 46 Issue: 5 Pages: 818-834.e4
- DOI
  10.1016/j.immuni.2017.04.022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08629, KAKENHI-PROJECT-16H05205
[Journal Article] The E-Id Protein Axis Specifies the Innate and Adaptive Lymphoid Branches of the Immune System2017
- Author(s)
  Masaki Miyazaki, Kazuko Miyazaki, Kenian Chen, Yi Jin, Jacob Turner, Amanda J. Moore, Rintaro Saito, Kenichi Yoshida, Seishi Ogawa, Hans-Reimer Rodewald, Yin C Lin, Hiroshi Kawamoto and Cornelis Murre
- Journal Title
  
  Immunity
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06330
[Journal Article] A 5' untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model.2010
- Author(s)
  Nagamachi A., Htun P.W., Ma F., Miyazaki K., Yamasaki N., Kanno M., Inaba T., Honda Z.I., Okuda T., Oda H., Tsuji K., Honda H.
- Journal Title
  
  Dev Biol. 345
  
  Pages: 226-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390271
[Journal Article] Identification of Zfp521/ZNF521 as acooperative gene for E2A-HLF to develop acute B-lineage leukemia.2010
- Author(s)
  Yamasaki N., Miyazaki K., Nagamachi A., Koller R., Oda H., Miyazaki M., Sasaki T., Honda Z, Wolff L., Inaba T., Honda H.
- Journal Title
  
  Oncogene 29
  
  Pages: 1963-1975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390271
[Journal Article] Haploinsufficiency and acquired loss of Bcl11b and H2AX induced blast crisis of chronic myelogenous leukemia in a transgenic mouse model.2009
- Author(s)
  Nagamachi A., Yamasaki N., Miyazaki K., Oda H., Miyazaki M., Honda Z-i., Kominami R., Inaba T., Honda H.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 1219-1226
- NAID
  10027191952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390271
[Journal Article] Polycomb group gene mel-18 regulates early T progenitor expansion by maintaining the expression of Hes-1,a target of the Notch pathway2005
- Author(s)
  Miyazaki, M.
- Journal Title
  
  The Journal of Immunology 174・5
  
  Pages: 2507-2516
- Data Source
  KAKENHI-PROJECT-15790152
[Presentation] 悪性リンパ腫の進展におけるregulome調節と３Dゲノム構造変容の解析2023
- Author(s)
  宮崎和子、宮崎正輝
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K08370
[Presentation] Synergistic action between E2A and Notch signal determines the cell fate of T cell versus innate lymphoid cell in the thymus2022
- Author(s)
  宮崎和子
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-21K08370
[Presentation] The Synergic Role of E2A and Notch signaling in T cell lineage-specific enhancer regulome2021
- Author(s)
  宮崎和子
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-21K08370
[Presentation] ヒストン脱メチル化酵素Fbxl10の7q-AML/MDS発症過程への関与2009
- Author(s)
  長町安希子, 松井啓隆, 安藝大輔, 尾崎佑子, 麻生博也, 宮崎和子, 山崎憲政, 小田秀明, 稲葉俊哉, 本田浩章
- Organizer
  第71回日本血液学会学術集会国立京都国際会館
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] ヒストン脱メチル化酵素Fbxl10の7q-AML/MDS発症過程への関与2009
- Author(s)
  長町安希子, 松井啓隆, 安藝大輔, 尾崎佑子, 麻生博也, 宮崎和子, 山崎憲政, 小田秀明, 稲葉俊哉, 本田浩章
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] レトロウイルスを用いたTITANノックアウトマウスにおける白血病発症機構の解析2008
- Author(s)
  長町安希子, 麻生博也, 松井啓隆, 宮崎和子, 山崎憲政, 稲葉俊哉, 本田浩章
- Organizer
  第49回原子爆弾後障害研究会
- Place of Presentation
  長崎
- Year and Date
  2008-06-08
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] 7q-候補遺伝子TITANの欠失はTGFβ経路抑制やエピジェネティック変化と協調して白血病に関する2008
- Author(s)
  長町安希子, 麻生博也, 松井啓隆, 安藝大輔, 尾崎佑子, 宮崎和子, 山崎憲政, 小田秀明, 稲葉俊哉, 本田浩章
- Organizer
  第70回日本臨床血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] Haploinsufficiency and deficiency of a 7q gene Titan (Samd9L) predispose leukemia development in cooperation with deregulated expression of a transcription factor, Evi1, or a histone demethylase, Fbxl10.2008
- Author(s)
  Nagamachi A., Asou H., Matsui H., Ozaki Y., Aki D., Miyazaki K., Yamasaki N., Miyazaki M., Wolff L, Koller R., Oda H, Inaba T., Honda H.
- Organizer
  The 50^<th> Annual Meeting of American Society of Hematology
- Place of Presentation
  San Francisco, CA.
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-20390271

1. INABA Toshiya (60281292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. HONDA Hiroaki (40245064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. MATSUI Hirotaka (60379849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. ASOU Hiroya (60243614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. AKI Daisuke (50420500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. KATO Yukio (10112062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SHEN Ming (20294572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NOSIRO Mitsuhide (00144858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 来田吉弘 (10304429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. LEE Kaechoon

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. V.SEGRE Gino

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 榛葉旭恒

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 宮崎正輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Miyazaki Kazuko 宮崎 和子

MIYAZAKI Kazuko 宮崎 和子

宮崎 和子 ミヤザキ カズコ

中舛 和子 ナカマス カズコ

Research Projects

Research Products

Co-Researchers

コヒーシンによるTreg細胞特異的なゲノム構造制御と組織炎症抑制の分子機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of molecular mechanism involved in 3D genome structure in the progression of malignant lymphomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyisis of regulome through E/Id protein axis in Treg cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of transcriptional regulation in Treg cells by Id-proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

bHLH型転写因子Dec1による制御性T細胞の新規維持機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of candidate responsible genes for 7q deletion in MDS/AML

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

遺伝子導入マウスを用いたT細胞の機能制御と低酸素での転写因子DEC1の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規転写因子DEC1の低酸素応答における機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

転写因子DEC1/2の低酸素応答における新規経路と機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

膜結合型トランスフェリン様蛋白遺伝子の発現調節機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of PTH and PTH-related peptide in skeletal development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The E-Id Axis Instructs Adaptive Versus Innate Lineage Cell Fate Choice and Instructs Regulatory T Cell Differentiation2022

Author(s)

Miyazaki Kazuko 宮崎和子

MIYAZAKI Kazuko 宮崎和子

宮崎和子ミヤザキカズコ

中舛和子ナカマスカズコ