Honda Hiroaki 本田浩章

… Alternative Names

HONDA Hiroaki 本田浩章

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Researcher Number	40245064
Other IDs
External Links
Affiliation (Current)	2025: 東京女子医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 東京女子医科大学, 医学部, 教授 2002 – 2016: 広島大学, 原爆放射線医科学研究所, 教授 2006 – 2007: 広島大学, 原爆放射線医学研究所, 教授 2004: 広島大学, 原爆放射線医学研究所, 教授 1999: 東京大学, 医学部・付属病院, 助手 … More 1997 – 1999: 東京大学, 医学部附属病院, 助手 1996 – 1999: Tokyo University, Medical Department, Assistant professor, 医学部・附属病院, 助手 1997: 東京大学, 医学部・付属病院, 助手 1997: 東大, 医学部附属病院, 助手 1993 – 1995: 自治医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Hematology / Hematology / Basic Section 50010:Tumor biology-related / Basic Section 54010:Hematology and medical oncology-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Experimental pathology / Tumor biology Except Principal Investigator Hematology / 膠原病・アレルギー・感染症内科学 / Hematology … More / Basic Section 54020:Connective tissue disease and allergy-related / Metabolomics / Pathological medical chemistry / Basic Section 56030:Urology-related / Basic Section 55050:Anesthesiology-related / Basic Section 50010:Tumor biology-related / Basic Section 54010:Hematology and medical oncology-related / Urology / Tumor biology / Rehabilitation science/Welfare engineering / Molecular biology / Risk sciences of radiation and chemicals / Science and Engineering / Biological Sciences / General medical chemistry Less
Keywords	Principal Investigator トランスジェニックマウス / エピジェネティクス / ヒストンメチル化・脱メチル化 / ヒストン修飾 / ヒストン脱メチル化 / 造血幹細胞 / 白血病 / ヒストン脱メチル化酵素 / PCR / UTX, UTY … More / UTX、UTY / ヒストン修飾因子 / UTY / UTX / HLF / E2A / BXH2 / ABL / p210BCR / CML / ヒストンH3K27 / コンディショナルノックアウトマウス / Fbxl10 / 泌尿器科腫瘍 / 炎症性経路 / 泌尿器科系腫瘍 / COMPASS-like complex / ヒストンメチル化・脱メチル / 造血器腫瘍 / 脱メチル化活性 / 抗加齢療法 / 老化 / 幹細胞 / Uty / 幹細胞老化 / Utx / transcription factors / retrovirus / conditional knockin mice / disease mode mice / モデルマウス / 変異遺伝子 / 誘導可能 / 後天性 / 転写因子 / レトロウイルス / コンディショナルノックインマウス / 疾患モデルマウス / conditional knockout mice / knockout mice / actin / p130 Cas (Cas) / アクチン / ノックアウトマウス / アダプター分子 / p130Cas(Cas) / blast crisis / transgenic mice / BHX2 / 急性転化 / tyrosine phosphatase / チロシレフォスファターゼ / チロシンフォスファターゼ / チロシンファスファターゼ / ヒストンH3K27メチル化 / Jmjd3, Utx / JMJD3, UTX / PRC2 / 骨髄異形成症候群 / EED / ポリコーム複合体 / 酸化的リン酸化 / エネルギー代謝 / 酸化的リン酸化経路 / Kdm2b / Fbx110 / がん抑制遺伝子 / トランスポゾン / 慢性骨髄性白血病 / LTK / abl> / p210^<bcr / Ph^1染色体 / チロシン脱リン酸化酵素 / 血液細胞 / type-III / チロシンフォスファターゼ(PTPase) … More Except Principal Investigator シグナル伝達 / 転写因子 / 全身性エリテマトーデス / Fc受容体 / SH3 / アポトーシス / サイトカイン / チロシンキナーゼ / FcgRIIB / Notch / CD34 / エピジェネティクス / 自己免疫疾患 / 遺伝子多型 / 膜貫通部位 / MDS / 白血病 / ノックアウトマウス / 遺伝子治療 / UTX / TFG / インスリン / 糖尿病 / 代謝 / SLE / 骨髄異形成症候群 / Src family kinase / 脂質ラフト / cytokine / apoptosis / Hsc70 / p27 / Bim / GATA2 / LTC-IC / アデノウイルス / GATA-2 / Jagged1 / Smad3 / JNK / TGFβ / Evi-1 / Cas / C3H10T1 / ストローマ細胞 / 放射線 / 膜貫通ドメイン / タンパク質間結合 / 多型 / 細胞膜貫通部位 / 免疫グロブリンFc受容体 / 中心体 / エンドソーム代謝 / 遺伝子欠損マウス / 発がん抑制遺伝子 / 7番染色体欠損 / 骨髄性白血病 / MLL / チロシンリン酸化 / 転写伸長因子 / t(11;19) / MEN / RNAポリメラーゼII伸長因子 / トランスジェニックマウス / Fyn / インテグリン / v-Crk / Src / 自殺遺伝子 / 造血幹細胞 / 転写調節 / aging / prostate cancer / 血圧 / Meis1 / Hox / 白血病幹細胞 / 急性骨髄性白血病 / 好中球 / ミトコンドリア / NETs / ヒドロキシクロロキン / 造血器腫瘍 / IBD / 構造計算 / 免疫創薬標的 / 創薬標的 / 免疫抑制シグナル / membrane-spanning 4 / Fc gamma RIIa / Fc gamma RIIb / IgG Fc受容体 / 2量体 / Fc(gamma)RIIB / TMD4ファミリー / 発現制御 / 遺伝子 / ヒストン脱メチル化酵素 / 遺伝子改変マウス / Utx / Jmjd3 / 前立腺癌 / EML4-ALK 融合遺伝子 / 放射線被曝 / 組織学的特徴 / コンディショナルトランスジェニックマウス / 甲状腺乳頭がん / EML4-ALK融合遺伝子 / インスリン分泌 / インスリン抵抗性 / メタボシックシンドローム / LUBAC / 肝細胞 / 肥満 / メタボリックシンドローム / プロリン異性化酵素 / Pin1 / 糖・脂質代謝 / ＴＦＧ / 骨代謝 / メカノバイオロジー / リハビリテーション / マクロファージ / 炎症 / 不動性筋萎縮 / 抗炎症・抗老化 / 適度な運動 / メカニカルストレス / oligomerization / Lyn / interface / transmembrane domain / FcgRIIA / B細胞 / FcγRIIA / 受容体会合面 / FcyRIIA / FcyRIIB / nuclear morphology / mitotic abnormiality / centrosome / chromosome instability / mvelodysolastic syndrome / 7q / 7 / 染色体散乱 / 紡錘糸 / マイクロアレイCGH法 / 微小染色体欠失 / AML / 核形態異常 / 細胞分裂異常 / 染色体不安定性 / 7番染色体長腕 / lipid rafts / polymorphism / systemic lupus erythematodes / yeast 2-hybrid法 / src family kinase / CD72 / FcγRIIB / mRNA stability / Bcl-xL / CML / mRNA半減期 / differentiation inhibition / hematopoiesis / phosphorylation / cleavage / signal / 分化抑制 / DSL蛋白質 / Notchリガンド / 分子抑制 / 造血 / リン酸化 / 分子内切断 / シグナル / colony-forming unit / long-term culture-initiating cell / CD34+cells / epidermal growth factor / adenovirus vector / hematopoietic stem cell / ex vivo expansion / SCF / インターロイキン6(IL-6) / 血液前駆細胞の体外増幅 / EGF受容体、組み換えアデノウイルス / 上皮細胞増殖因子(EGF) / 体外増幅 / 未熟造血細胞 / コロニー / 上皮細胞増殖因子 / CD34陽性細胞 / transcription factor / active Notch1 / differentiation / DSL domain / EGF受容体 / ES細胞 / 自己複製能 / EGF様リピート / Notch3 / Notch2 / Notch1 / 活性化型Notch1 / 細胞分化 / DSLドメイン / Notch蛋白質 / Apoptosis / Stress / Cell growth / Leukemia / 足場非依存性増殖 / MEN遺伝子 / MLL遺伝子 / t(11;19)転座型白血病 / 増殖抑制因子 / MAP kinase / zinc finger / 核内蛋白質 / ストレス刺激 / 増殖抑制 / smad3 / myofibril / knockout mouse / focal adhesion / subcellular localization / アクチン線維 / 細胞接着 / Hematopoiesis-supporting ability / Differentiation induction / 2 cell / Preadipocyte / Stromal cell / 造血支持能 / 分化誘導 / 2細胞 / 前脂肪細胞 / Anti-sense / Protein-tyrosine kinase / レトロウィルス / アンチセンス / DNA損傷 / 非相同末端結合 / 相同組換え / DNA修復 / 治療標的 / 翻訳制御 / 発がん制御遺伝子 / エピゲノム制御 / モノソミー7 / 骨髄系腫瘍 / 分裂異常 / 分裂異常期 / 分裂期異常 / テストステロン / EDCs / プロモーター / エストロゲン受容体発現 / ノックイン / ノックアウト / FAK / 血管拡張 / c-Src / c-Crk / actin線維の束状形成 / p130^<Cas> / AP‐1活性 / ホメオボックス / 心筋細胞 / bHLH転写因子 / 平滑筋細胞 / 神経堤細胞 / エンドセリン / ホメオボックス遺伝子 / 発生 / 心臓 / 非ホジキンリンパ腫 / 急性リンパ性白血病 / 細胞周期 / MLH1遺伝子 / DNAミスマッチ修復 / p53遺伝子 / Rb遺伝子 / p15遺伝子 / p16遺伝子 / 癌抑制遺伝子 / リンパ系腫瘍 / SHZ / p-130^<cas> / G-CSF / エストロゲン受容体 / Fas / SH2 / Fak / P130^<cas> / ストロース細胞 / レトロウイルスベクター / 遺伝子導入 / インターロイキン5 / 成人T細胞性白血病 / ストレス蛋白質 / レドックス Less

Hox関連白血病におけるDnajc10による白血病幹細胞制御機構の解明
- Principal Investigator
  
  岩崎正幸
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Women's Medical University
Mechanisms for sevoflurane-induced hypotension described by genetically modified mice and telemetry and its clinical application
- Principal Investigator
  
  長坂安子
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Tokyo Women's Medical University
Elucidation of aging reprogramming and cancer stem cell control mechanisms using a novel prostate cancer mouse model
- Principal Investigator
  
  井手久満
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Juntendo University
Elucidation of molecular mechanisms underlying development of malignant tumors with loss-of-function mutations of UTX, a histone modifier, mainly focusing on urological tumors.Principal Investigator
- Principal Investigator
  
  本田浩章
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Women's Medical University
ヒストン修飾因子に注目した骨髄異形成症候群と自己免疫疾患の共通分子基盤の解明
- Principal Investigator
  
  岩崎正幸
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Tokyo Women's Medical University
Dissection of innate immune pathogenesis of SLE by identifying novel hydroxychloroquine's mode of action
- Principal Investigator
  
  KONO HAJIME
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Teikyo University
Elucidation of mechanisms underlying stem cell aging induced by deregulation of histone modifications and development of anti-aging therapies by maintaining their functionsPrincipal Investigator
- Principal Investigator
  
  HONDA HIROAKI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Tokyo Women's Medical University
Functional analyses of enzymatic activity- and complex formation-dependent roles of UTX in the regulation of hematopoietic stem cells and development of hematopoietic diseasesPrincipal Investigator
- Principal Investigator
  
  HONDA HIROAKI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Tokyo Women's Medical University
A novel functional antigen receptor TMD module identified as an SLE-associating SNP-related structure
- Principal Investigator
  
  Honda Zen-ichiro
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Ochanomizu University
Clarification of epigenetic mechanism of prostate cancer development using Jmjd3 overexpressing mice
- Principal Investigator
  
  Iwamoto Hideo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Higashihiroshima Medical Center
  Department of Clinical Research, National Hospital Organization Kure Medical Center
Molecular Mechanisms of How Mechanical Stress Regulates Inflammation of Locomotive Organs
- Principal Investigator
  
  Sawada Yasuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  National Rehabilitation Center for Persons with Disabilities
Analysis of pathogenic mechanisms of myelodysplastic syndrome by deregulation of histone H3K27Principal Investigator
- Principal Investigator
  
  Honda Hiroaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Hiroshima University
Role of EED mutation in hematologic malignancy
- Principal Investigator
  
  UEDA Takeshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kindai University
  Hiroshima University
Roles of trk-fused gene product protein
- Principal Investigator
  
  Asano Tomoichiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University
Roles of Pin1 and PAR 14 on the metabolic regulations
- Principal Investigator
  
  Asano Tomoichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University
Generation of ES cells to meseare DNA repair activity with reporter genes
- Principal Investigator
  
  KOBAYASHI Junya
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyoto University
Analysis of tumorigenic mechanisms by activation of oxidative phosphorylation pathwayPrincipal Investigator
- Principal Investigator
  
  HONDA Hiroaki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Hiroshima University
A study on biological significance of EML4-ALK fusion gene in radiation thyroid cancer
- Principal Investigator
  
  HAMATANI Kiyohiro
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Radiation Effects Research Foundation
Analysis of leukemogenic mechanisms by deregulated expression of histone demethylase Fbxl10Principal Investigator
- Principal Investigator
  
  HONDA Hiroaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Hiroshima University
Roles of impairment of centrosome maturation in leukemogenesis
- Principal Investigator
  
  INABA Toshiya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Hiroshima University
Targeting Mnk/eIF4E pathway for cancer therapy
- Principal Investigator
  
  UEDA Takeshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hiroshima University
Analysis of the novel FcgR transmembrane interface motif displaying a polymorphism associate with human SLE susceptibility
- Principal Investigator
  
  HONDA Zen-ichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Ochanomizu University
  The University of Tokyo
Functional analysis of candidate responsible genes for 7q deletion in MDS/AML
- Principal Investigator
  
  INABA Toshiya
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Hiroshima University
Isolation of novel anti-oncogenes using transposon in model mice for chronic myelogenous leukemiaPrincipal Investigator
- Principal Investigator
  
  HONDA Hiroaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Hiroshima University
Isolation and characterization of candidate myeloid tumor-suppressor genes on the long arm of chromosome7.
- Principal Investigator
  
  INABA Toshiya
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Hiroshima University
Generation and analysis of novel model mice that acquiredly express mutated genesPrincipal Investigator
- Principal Investigator
  
  HONDA Hiroaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Hiroshima University
Patho-physiological analysis of collagen vascular disease development results from dysfunction of the membrane microdomain, lipid rafts
- Principal Investigator
  
  HONDA Zen-ichiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
Functional analysis of Cas in adult tissues using conditional knockout micePrincipal Investigator
- Principal Investigator
  
  HONDA Hiroaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  HIROSHIMA UNIVERSITY
Defective immuno-surveillance owing to the disorganization of lipid rafts and its roles in the pathogenesis of autoimmune diseases
- Principal Investigator
  
  HONDA Zen-ichiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
エストロゲン受容体プロモーター遺伝子導入/改変動物による内分泌攪乱物質作用の解析
- Principal Investigator
  
  藤本成明
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Hiroshima University
Analysis of the Bim/Dlc protein complex regulating the survival of hematopoietic cells under the control of cytokines.
- Principal Investigator
  
  INABA Toshiya
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  HIROSHIMA UNIVERSITY
Investigation of mechanism(s) underlying blast crisis of chronic myelogenous leukemia (CML) and analysis of genes involved in blast crisis of CMLPrincipal Investigator
- Principal Investigator
  
  HONDA Hiroaki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  HIROSHIMA UNIVERSITY
Notch in hematopoiesis
- Principal Investigator
  
  CHIBA Shigeru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Tokyo Hospital
ノックアウトマウスを用いた新規情報伝達物質p130^<Cas>の生物学的機能解析
- Principal Investigator
  
  小川誠司
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
発生工学的手法を用いたヒト白血病モデルマウスの作製
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
心血管系の発生分化とその分子機構の解析
- Principal Investigator
  
  矢崎義雄
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Research Institute, International Medical Center of Japan
  The University of Tokyo
基本転写因子異常による造血幹細胞腫瘍化の機構の解析
- Principal Investigator
  
  三谷絹子
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
チロシンキナーゼTecの転写調節機構の解析と個体発現への応用Principal Investigator
- Principal Investigator
  
  本田浩章
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Analyses of a Novel Signaling Molecule, Cas
- Principal Investigator
  
  HIRAI Hisamaru
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Molecular biology
- Research Institution
  University of Tokyo
Analysis of molecular mechanisms of leukemia development
- Principal Investigator
  
  HIRAI Hisamaru
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Practical development of a novel method for hematopoietic stem cell expansion
- Principal Investigator
  
  HIRAI Hisamaru
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Ex vivo expansion of hematopoietic stem cells using adenovirus
- Principal Investigator
  
  CHIBA Shigeru
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Tokyo
トランスジェニックマウスを用いた心筋細胞におけるチロシンキナーゼLTKの機能の解析Principal Investigator
- Principal Investigator
  
  本田浩章
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
造血器腫瘍の予後に関する遺伝子診断法の開発
- Principal Investigator
  
  平井久丸
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
造血幹細胞への遺伝子導入のためのレトロウイルスベクター産生システムの改良
- Principal Investigator
  
  OZAWA Keiya
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
トランスジェニックマウスを用いたp210^<bcr/abl>の機能解析Principal Investigator
- Principal Investigator
  
  本田浩章
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
細胞接着・転移におけるCas/Fakの相互作用
- Principal Investigator
  
  堺隆一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
サイトカイン補充遺伝子療法のための自殺遺伝子を介した細胞レベルでの調節法の開発
- Principal Investigator
  
  小澤敬也
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
細胞がん化におけるP130^<cas>の役割
- Principal Investigator
  
  堺隆一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Jichi Medical University
Anolysis of a novel protein-tyrosine phosphatase in hemotopoietic systemPrincipal Investigator
- Principal Investigator
  
  HONDA Hiroaki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  UNIVERSITY OF TOKYO
  Jichi Medical University
造血幹細胞におけるTecチロシンキナーゼの解析
- Principal Investigator
  
  MANO Hiroyuki
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
Tecチロシンキナーゼを介する細胞増殖機構
- Principal Investigator
  
  間野博行
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
血液細胞の情報伝達機構におけるチロシン脱リン酸化酵素の機能の解析Principal Investigator
- Principal Investigator
  
  本田浩章
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Molecular study of hematopoiesis-supporting ability of C3H10T1/2 mouse embryo fibroblasts
- Principal Investigator
  
  OZAWA Keiya
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
レドックス蛋白質の機能解析および癌診断への応用
- Principal Investigator
  
  西田淳二
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Jichi Medical University
成人T細胞性白血病細胞に特異的な転写機構の解明と癌化との関連
- Principal Investigator
  
  西田淳二
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
血液細胞の情報伝達機構におけるチロシンフォスファターゼの解析Principal Investigator
- Principal Investigator
  
  本田浩章
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
A novel gene therapy against human leukemias : suppression of protein-tyrosine kinase activities
- Principal Investigator
  
  MANO Hiroyuki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
  The University of Tokyo

[Journal Article] UTX inactivation in germinal center B cells promotes the development of multiple myeloma with extramedullary disease2023
- Author(s)
  Rizq Ola、Mimura Naoya、Oshima Motohiko、Momose Shuji、Takayama Naoya、Itokawa Naoki、Koide Shuhei、Shibamiya Asuka、Miyamoto-Nagai Yurie、Rizk Mohamed、Nakajima-Takagi Yaeko、Aoyama Kazumasa、Wang Changshan、Saraya Atsunori、Ito Ryoji、Seimiya Masanori、et al
- Journal Title
  
  Leukemia
  
  Volume: 37 Issue: 9 Pages: 1895-1907
- DOI
  10.1038/s41375-023-01928-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07858, KAKENHI-PROJECT-22K08495, KAKENHI-PROJECT-23K05608, KAKENHI-PROJECT-23K06449, KAKENHI-PROJECT-23K07851, KAKENHI-PROJECT-20K07396, KAKENHI-PROJECT-21K08366, KAKENHI-PROJECT-22K16298, KAKENHI-PROJECT-22K16318, KAKENHI-PLANNED-19H05746, KAKENHI-PROJECT-19H05653, KAKENHI-PROJECT-23K27442
[Journal Article] The pathogenetic significance of exhausted T cells in a mouse model of mature B cell neoplasms2023
- Author(s)
  1.Shibamiya A, Miyamoto-Nagai Y, Koide S, Oshima M, Rizq O, Aoyama K, Nakajima-Takagi Y, Kato R, Kayamori K, Isshiki Y, Oshima-Hasegawa N, Muto T, Tsukamoto S, Takeda Y, Koyama-Nasu R, Chiba T, Honda H, Yokote K, Iwama A, Sakaida E, Mimura N.
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: － Issue: 8 Pages: 2635-2648
- DOI
  10.1007/s00262-023-03447-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19497, KAKENHI-PROJECT-22K08495, KAKENHI-PROJECT-23K07851, KAKENHI-PROJECT-22K16298, KAKENHI-PLANNED-19H05746, KAKENHI-PROJECT-19H05653, KAKENHI-PROJECT-23K27442
[Journal Article] Targeting Poly(ADP)ribose polymerase in BCR/ABL1-positive cells2023
- Author(s)
  Hiroki Haruka、Ishii Yuko、Piao Jinhua、Namikawa Yui、Masutani Mitsuko、Honda Hiroaki、Akahane Koshi、Inukai Takeshi、Morio Tomohiro、Takagi Masatoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 7588-7588
- DOI
  10.1038/s41598-023-33852-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24298, KAKENHI-PROJECT-23K27442
[Journal Article] Elevated stress response marks deeply quiescent reserve cells of gastric chief cells2023
- Author(s)
  Shiokawa Daisuke、Sakai Hiroaki、Koizumi Miho、Okimoto Yoshie、Mori Yutaro、Kanda Yusuke、Ohata Hirokazu、Honda Hiroaki、Okamoto Koji
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 1183-1183
- DOI
  10.1038/s42003-023-05550-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07037, KAKENHI-PROJECT-21H03081, KAKENHI-PROJECT-23K27442
[Journal Article] MBTD1 preserves adult hematopoietic stem cell pool size and function2023
- Author(s)
  Takubo Keiyo、Htun Phyo Wai、Ueda Takeshi、Sera Yasuyuki、Iwasaki Masayuki、Koizumi Miho、Shiroshita Kohei、Kobayashi Hiroshi、Haraguchi Miho、Watanuki Shintaro、Honda Zen-ichiro、Yamasaki Norimasa、Nakamura-Ishizu Ayako、Arai Fumio、Motoyama Noboru、Hatta Tomohisa、Natsume Tohru、Suda Toshio、Honda Hiroaki
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 32
- DOI
  10.1073/pnas.2206860120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16333, KAKENHI-PROJECT-21K08378, KAKENHI-PROJECT-23K07134, KAKENHI-PROJECT-21K08431, KAKENHI-PROJECT-22K19550, KAKENHI-PROJECT-21H02957, KAKENHI-PROJECT-23K27442
[Journal Article] MBTD1 preserves adult hematopoietic stem cell pool size and function2023
- Author(s)
  Keiyo Takubo, Phyo Wai Htun, Takeshi Ueda, Yasuyuki Sera, Masayuki Iwasaki, Miho Koizumi, Kohei Shiroshita, Hiroshi Kobayashi, Miho Haraguchi, Shintaro Watanuki, Zen-ichiro Honda, et. at.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08384
[Journal Article] Wnt5a plays a critical role in anal opening in mice at an early stage of embryonic development2022
- Author(s)
  Nakata Mitsuyuki、Honda Hiroaki、Iwama Atsushi、Terui Keita、Komatsu Shugo、Shibata Ryohei、Hishiki Tomoro
- Journal Title
  
  Pediatric Surgery International
  
  Volume: 38 Issue: 5 Pages: 743-747
- DOI
  10.1007/s00383-022-05103-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19H03693
[Journal Article] The unique function of p130Cas in regulating the bone metabolism2022
- Author(s)
  Jimi Eijiro、Honda Hiroaki、Nakamura Ichiro
- Journal Title
  
  Pharmacology and Therapeutics
  
  Volume: 230 Pages: 107965-107965
- DOI
  10.1016/j.pharmthera.2021.107965
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19H03693
[Journal Article] UTX deficiency in neural stem/progenitor cells results in impaired neural development, fetal ventriculomegaly, and postnatal death2022
- Author(s)
  Koizumi M, Eto H, Saeki M, Seki M, Fukushima T, Mukai S, Ide H, Sera Y, Iwasaki M, Suzuki Y, Tohei A, Kishi Y, Honda H.
- Journal Title
  
  FASEB journal
  
  Volume: 36(12) Issue: 12 Pages: 22662-22662
- DOI
  10.1096/fj.202201002rr
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08378, KAKENHI-PROJECT-22K19823, KAKENHI-PROJECT-22K16333, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H03179, KAKENHI-PROJECT-19K17918, KAKENHI-PUBLICLY-21H00242, KAKENHI-PUBLICLY-22H04687
[Journal Article] Deletion of epithelial cell-specific p130Cas impairs the maturation stage of amelogenesis2022
- Author(s)
  Inoue Akane、Kiyoshima Tamotsu、Yoshizaki Keigo、Nakatomi Chihiro、Nakatomi Mitsushiro、Ohshima Hayato、Shin Masashi、Gao Jing、Tsuru Kanji、Okabe Koji、Nakamura Ichiro、Honda Hiroaki、Matsuda Miho、Takahashi Ichiro、Jimi Eijiro
- Journal Title
  
  Bone
  
  Volume: 154 Pages: 116210-116210
- DOI
  10.1016/j.bone.2021.116210
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10065, KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-19K10054, KAKENHI-PROJECT-20K10096, KAKENHI-PROJECT-20K21672, KAKENHI-PROJECT-21K19610, KAKENHI-PROJECT-20K21681, KAKENHI-PROJECT-23K21498
[Journal Article] The Loss of H3K27 Histone Demethylase Utx in T Cells Aggravates Allergic Contact Dermatitis2021
- Author(s)
  Inoue Takashi、Omori-Miyake Miyuki、Maruyama Saho、Okabe Masataka、Kuwahara Makoto、Honda Hiroaki、Miura Hiromasa、Yamashita Masakatsu
- Journal Title
  
  The Journal of Immunology
  
  Volume: 207 Issue: 9 Pages: 2223-2234
- DOI
  10.4049/jimmunol.2001160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22546, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-20H04948, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-20H03504, KAKENHI-PROJECT-21K08205
[Journal Article] Progress of genome editing technology and developmental biology useful for radiation research2021
- Author(s)
  Miura Kento、Ogura Atsuo、Kobatake Kohei、Honda Hiroaki、Kaminuma Osamu
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 62 Issue: Supplement_1 Pages: i53-i63
- DOI
  10.1093/jrr/rraa127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19H03145, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-19K16017
[Journal Article] Pathological Role of Pin1 in the Development of DSS-Induced Colitis2021
- Author(s)
  Matsunaga Yasuka、Hasei Shun、Yamamotoya Takeshi、Honda Hiroaki、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Ono Hiraku、Ito Hisanaka、Okabe Takayoshi、Asano Tomoichiro、Nakatsu Yusuke
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 5 Pages: 1230-1230
- DOI
  10.3390/cells10051230
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-19K08982, KAKENHI-PROJECT-21K08570, KAKENHI-PROJECT-21K08580
[Journal Article] DEC1 deficiency results in accelerated osteopenia through enhanced DKK1 activity and attenuated PI3KCA/Akt/GSK3β signaling2021
- Author(s)
  He Shuangcheng、Guan Yu、Wu Yichen、Zhu Ling、Yan Bingfang、Honda Hiroaki、Yang Jian、Liu Wei
- Journal Title
  
  Metabolism
  
  Volume: 118 Pages: 154730-154730
- DOI
  10.1016/j.metabol.2021.154730
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19H03693
[Journal Article] UTX maintains functional integrity of murine hematopoietic system by globally regulating aging-associated genes.2021
- Author(s)
  Sera Y; Nakata Y; Ueda T; Yamasaki N; Koide S; Kobayashi H; Ikeda KI; Kobatake K; Iwasaki M; Oda H; Wolff L; Kanai A; Nagamachi A; Inaba T; Sotomaru Y; Ichinohe T; Koizumi M; Miyakawa Y; Honda ZI; Iwama A; Suda T; Takubo K; Honda H
- Journal Title
  
  Blood.
  
  Volume: 137 Issue: 7 Pages: 908-922
- DOI
  10.1182/blood.2019001044
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07346, KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19K17918, KAKENHI-PROJECT-19H05653, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-18K08357, KAKENHI-PROJECT-18K18196, KAKENHI-PROJECT-19K17847, KAKENHI-PROJECT-19H01056, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-21K08378, KAKENHI-PROJECT-21K08395
[Journal Article] Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway2021
- Author(s)
  Fujino Takeshi、Goyama Susumu、Sugiura Yuki、Inoue Daichi、Asada Shuhei、Yamasaki Satoshi、Matsumoto Akiko、Yamaguchi Kiyoshi、Isobe Yumiko、Tsuchiya Akiho、Shikata Shiori、Sato Naru、Morinaga Hironobu、Fukuyama Tomofusa、Tanaka Yosuke、Fukushima Tsuyoshi、Takeda Reina、Yamamoto Keita、Honda Hiroaki et al
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1826-1826
- DOI
  10.1038/s41467-021-22053-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-19K22546, KAKENHI-PLANNED-19H05746, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-19J01570, KAKENHI-PROJECT-19H03685
[Journal Article] Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL2020
- Author(s)
  Atsushi Watanabe, Kunio Miyake, Jessica Nordlund, Ann-Christine Syvanen, Louise van der Weyden, Hiroaki Honda, Norimasa Yamasaki, Akiko Nagamachi, Toshiya Inaba, Tomokatsu Ikawa, Kevin Y Urayama, Nobutaka Kiyokawa, Akira Ohara, Shunsuke Kimura, Yasuo Kubota, Junko Takita, Hiroaki Goto, Kimiyoshi Sakaguchi, et al.
- Journal Title
  
  Blood
  
  Volume: 136 Issue: 20 Pages: 2319-2333
- DOI
  10.1182/blood.2019004090
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08318, KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-20K21707, KAKENHI-PROJECT-19KK0222, KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-19H03615, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-20H03928, KAKENHI-PROJECT-18K08357, KAKENHI-PROJECT-20H00528
[Journal Article] Kdm6a Deficiency Activates Inflammatory Pathways, Promotes M2 Macrophage Polarization, and Causes Bladder Cancer in Cooperation with p53 Dysfunction2020
- Author(s)
  Kobatake Kohei et al., Honda Zen-ichiro et al. and Honda Hiroaki
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 26 Issue: 8 Pages: 2065-2079
- DOI
  10.1158/1078-0432.ccr-19-2230
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08384, KAKENHI-PROJECT-19K07434, KAKENHI-PROJECT-19K17918, KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-19K09729, KAKENHI-PROJECT-20K07346, KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-18K18196, KAKENHI-PROJECT-19H01056
[Journal Article] Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM2020
- Author(s)
  Harachi Mio、Masui Kenta、Honda Hiroaki、Muragaki Yoshihiro、Kawamata Takakazu、Cavenee Webster K.、Mischel Paul S.、Shibata Noriyuki
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 18 Issue: 8 Pages: 1142-1152
- DOI
  10.1158/1541-7786.mcr-20-0024
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07649, KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19H03693
[Journal Article] HHEX promotes myeloid transformation in cooperation with mutant ASXL1.2020
- Author(s)
  Takeda R, Asada S, Park SJ, Yokoyama A, Becker H, Kanai A, Visconte V, Hershberger C, Hayashi Y, Yonezawa T, Tamura M, Fukushima T, Tanaka Y, Fukuyama T, Matsumoto A, Yamasaki S, Nakai K, Yamazaki S, Inaba T, Shibata T, Inoue D, Honda H, Goyama S, Maciejewski J, Kitamura T.
- Journal Title
  
  Blood
  
  Volume: 136 Pages: 1670-1684
- DOI
  10.1182/blood.2019004613
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19KK0216, KAKENHI-PLANNED-19H05746, KAKENHI-PROJECT-20H00537, KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-19J01570, KAKENHI-PROJECT-18K18196
[Journal Article] TX regulates the differentiation of a subset of bipolar cells in the mouse retina.2020
- Author(s)
  Umutoni D, Iwagawa T, Baba Y, Tsuhako A, Honda H, Aihara M, Watanabe S.
- Journal Title
  
  Genes Cells
  
  Volume: 25 Issue: 6 Pages: 402-412
- DOI
  10.1111/gtc.12767
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-16H06279
[Journal Article] Accumulation of versican facilitates wound healing: Implication of its initial ADAMTS-cleavage site2020
- Author(s)
  Islam Shamima、Chuensirikulchai Kantinan、Khummuang Saichit、Keratibumrungpong Tanyaporn、Kongtawelert Prachya、Kasinrerk Watchara、Hatano Sonoko、Nagamachi Akiko、Honda Hiroaki、Watanabe Hideto
- Journal Title
  
  Matrix Biology
  
  Volume: 87 Pages: 77-93
- DOI
  10.1016/j.matbio.2019.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02646, KAKENHI-PROJECT-19H03693
[Journal Article] Jmjd3 plays pivotal roles in the proper development of early-born retinal lineages, amacrine, horizontal, and retinal ganglion cells.2020
- Author(s)
  Iwagawa T, Honda H, Watanabe S.
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 61 Issue: 11 Pages: 43-43
- DOI
  10.1167/iovs.61.11.43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19H03693
[Journal Article] Accumulation of versican facilitates wound healing: implication of its initial ADAMTS-cleavage site.2020
- Author(s)
  Islam S, Chuensirikulchai K, Khummuang S, Keratibumrungpong T, Kongtawelert P, Kasinrerk W, Hatano S, Nagamachi A, Honda H, *Watanabe H.
- Journal Title
  
  Matrix Biol
  
  Volume: 87 Pages: 77-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22546
[Journal Article] The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling.2019
- Author(s)
  4.Zhu Z, Yichen W, Ziheng Z, Dighao G, Ming L, Wei L, Enfang S, Gang H, Honda H, Jian Y
- Journal Title
  
  Aging
  
  Volume: 11 Issue: 24 Pages: 12733-12753
- DOI
  10.18632/aging.102599
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19H03693
[Journal Article] Discrimination of dormant and active hematopoietic stem cells by G0 markers reveals dormancy regulation by cytoplasmic calcium.2019
- Author(s)
  5.Fukushima T, Tanaka Y, Hamey FK, Chang CH, Oki T, Asada S, Hayashi Y, Fujino T, Yonezawa T, Takeda R, Kawabata KC, Fukuyama T, Umemoto T, Takubo K, Takizawa H, Goyama S, Ishihama Y, Honda H, Gottgens B, Kitamura T.
- Journal Title
  
  Cell Rep
  
  Volume: 29 Issue: 12 Pages: 4144-4158
- DOI
  10.1016/j.celrep.2019.11.061
- NAID
  120006892032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-19J01570, KAKENHI-PROJECT-18K19570
[Journal Article] Identification of cooperative genes for E2A-PBX1 to develop acute lymphoblastic leukemia.2016
- Author(s)
  Sera Y, Yamasaki N, Oda H, Nagamachi A, Wolff L, Inukai T, Inaba T, Honda H.
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Issue: 7 Pages: 890-898
- DOI
  10.1111/cas.12945
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293227, KAKENHI-PROJECT-15K09645, KAKENHI-PROJECT-16K19575
[Journal Article] ALKR1275Q perturbs extracellular matrix, enhances cell invasion and leads to the development of neuroblastoma in cooperation with MYCN.2016
- Author(s)
  Ueda T, Nakata Y, Yamasaki N, Oda H, Sentani K, Kanai A, Onishi N, Ikeda K, Sera Y, Honda ZI, Tanaka K, Sata M, Ogawa S, Yasui W, Saya H, Takita J, Honda H.
- Journal Title
  
  Oncogene.
  
  Volume: 無 Issue: 34 Pages: 4447-4458
- DOI
  10.1038/onc.2015.519
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-15J06501, KAKENHI-PROJECT-25460416, KAKENHI-PROJECT-15K14384, KAKENHI-PROJECT-26670493, KAKENHI-PROJECT-25293184, KAKENHI-PROJECT-26293242, KAKENHI-PROJECT-26293227, KAKENHI-PROJECT-16K08691
[Journal Article] Propagation of tri-methylated H3K27 regulated by EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression.2016
- Author(s)
  Ueda T, Nakata Y, Nagamachi A, Yamasaki N, Kanai A, Matsui H, Honda ZI, Oda H, Wolff L, Inaba T, Honda H.
- Journal Title
  
  PNAS
  
  Volume: 113(37) Issue: 37 Pages: 10370-10375
- DOI
  10.1073/pnas.1600070113
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01513, KAKENHI-PROJECT-15J06501, KAKENHI-PROJECT-26293227, KAKENHI-PROJECT-26460391, KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-15K09478, KAKENHI-PROJECT-16K19575
[Journal Article] Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency2016
- Author(s)
  Ikeda K-I, Ueda T, Yamasaki N, Nakata Y, Sera Y, Nagamachi A, Miyama T, Kobayashi H, TakuboK, Kanai A, Oda H, Wolff l, Honda Z-1, Ichinohe T, Matsubara A, Suda T, Inaba T, Honda H
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 29454-29454
- DOI
  10.1038/srep29454
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15J06501, KAKENHI-PROJECT-26293227, KAKENHI-PROJECT-26460391, KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-16K19575
[Journal Article] Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg22015
- Author(s)
  Ueda T, Nagamachi A, Takubo K, Yamasaki N, Matsui H, Kanai A, Nakata Y, Ikeda K Konuma T, Oda H, Wolff L, Honda Z, Wu X, Helin K, Iwama A, Suda T, Inaba T, Honda H.
- Journal Title
  
  Blood
  
  Volume: 125
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460391
[Journal Article] -7/7q- syndrome in myeloid-lineage hematopoietic malignancies: attempts to understand this complex disease entity.2015
- Author(s)
  Honda H, Nagamachi A, Inaba T.
- Journal Title
  
  Oncogene
  
  Volume: 34 Issue: 19 Pages: 2413-2425
- DOI
  10.1038/onc.2014.196
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860735, KAKENHI-PROJECT-26293227
[Journal Article] Prolyl Isomerase Pin1 Negatively Regulates AMPK by Associating with the CBS Domain in the γ-subunit.2015
- Author(s)
  Nakatsu, Y., Iwashita, M., Sakoda, H., Ono, H., Nagata, K., Matsunaga, Y., Fukushima, T., Fujishiro, M., Kushiyama, A., Kamata, H., Takahashi, S., Katagiri, H., Honda, H., Kiyonari, H., Uchida, T., and Asano, T.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Pages: 24255-24266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Overexpression of the shortest isoform of histone demethylase LSD1 primes hematopoietic stem cells for malignant transformation.2015
- Author(s)
  Wada T, Koyama D, Kikuchi J, Honda H, Furukawa Y.
- Journal Title
  
  Blood
  
  Volume: 125 Issue: 24 Pages: 3731-3746
- DOI
  10.1182/blood-2014-11-610907
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461430, KAKENHI-PROJECT-15K19557, KAKENHI-PROJECT-26293227
[Journal Article] Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg22015
- Author(s)
  Ueda T, Nagamachi A, Takubo K, Yamasaki N, Matsui H, Kanai A, Nakata Y, Ikeda K, Konuma T, Oda H, Wolff L, Honda Z, WuX, Helin K, Iwama A, Suda T, Inaba T, Honda H
- Journal Title
  
  Blood
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25640065
[Journal Article] Fbxl10 overexpression in murine hematopoietic stemcells induces leukemia involving metabolic activation and upregulation of Nsg22015
- Author(s)
  Ueda T, Nagamachi A, Takubo K, Yamasaki N, Matsui H, Kanai A, Nakata Y, Ikeda K Konuma T, Oda H, Wolff L, Honda Z, Wu X, Helin K, Iwama A, Suda T, Inaba T, Honda H.
- Journal Title
  
  Blood
  
  Volume: 125 Issue: 22 Pages: 3437-3446
- DOI
  10.1182/blood-2014-03-562694
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460391, KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15J06501, KAKENHI-PROJECT-26860735, KAKENHI-PROJECT-26293227
[Journal Article] Prolyl Isomerase Pin1 Negatively Regulates AMPK by Associating with the CBS Domain in the γ-subunit.2015
- Author(s)
  Nakatsu, Y., Iwashita, M., Sakoda, H., Ono, H., Nagata, K., Matsunaga, Y., Fukushima, T., Fujishiro, M., Kushiyama, A., Kamata, H., Takahashi, S., Katagiri, H., Honda, H., Kiyonari, H., Uchida, T., and Asano, T.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Pages: 24255-24266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] Acquired deficiency of A20 results in rapid apoptosis, systemic inflammation, and abnormal hematopoietic stem cell function2014
- Author(s)
  Nagamachi A, Nakata Y, Ueda T, Yamasaki N, Ebihara Y, Tsuji K, Honda Zi, Takubo K, Suda T, Oda H, Inaba T, Honda H
- Journal Title
  
  PLOS ONE
  
  Volume: 9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390253
[Journal Article] CIZ1, a p21Cip1/Waf1-interacting protein, functions as a tumor suppressor in vivo.2014
- Author(s)
  Nishibe R, Watanabe W, Ueda T, Yamasaki N, Koller R, Wolff L, Honda Z, Ohtsubo M, Honda H.
- Journal Title
  
  FEBS Lett.
  
  Volume: 587 Issue: 10 Pages: 1529-35
- DOI
  10.1016/j.febslet.2013.03.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591459
[Journal Article] Acquired deficiency of A20 results in rapid apoptosis, systemic inflammation, and abnormal hematopoietic stem cell function.2014
- Author(s)
  Nagamachi A, Nakata Y, Ueda T, Yamasaki N, Ebihara Y, Tsuji K, Honda Zi, Takubo K, Suda T, Oda H, Inaba T, Honda H
- Journal Title
  
  PLos One
  
  Volume: 9 Issue: 1 Pages: 1-10
- DOI
  10.1371/journal.pone.0087425
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390252, KAKENHI-PROJECT-23591459, KAKENHI-PROJECT-23689049, KAKENHI-PROJECT-24390272, KAKENHI-PUBLICLY-25118724, KAKENHI-PROJECT-25640065, KAKENHI-PROJECT-25670489, KAKENHI-PROJECT-26293243, KAKENHI-PROJECT-26670511
[Journal Article] The IL-2/CD25 Axis Maintains Distinct Subsets of Chronic Myeloid Leukemia–Initiating Cells.2014
- Author(s)
  Kobayashi CI, Takubo K, Kobayashi H, Nakamura-Ishizu A, Honda H, Kataoka K, Kumano K, Akiyama H, Sudo T, Kurokawa M, Suda T
- Journal Title
  
  Blood
  
  Volume: 123 Pages: 2540-2549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390252
[Journal Article] Acquired deficiency of a20 results in rapid apoptosis, systemic inflammation, and abnormal hematopoietic stem cell function2014
- Author(s)
  Nagamachi A, Nakata Y, Ueda T, Yamasaki N, Ebihara Y, Tsuji K, Honda Z, Takubo K, Suda T, Oda H, Inaba T, Honda H
- Journal Title
  
  PLoS On
  
  Volume: 9(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590364
[Journal Article] A long lasting puzzle for －7/7q－ syndrome.2014
- Author(s)
  Honda H, Inaba T
- Journal Title
  
  Oncotarget
  
  Volume: 5 Pages: 7-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390252
[Journal Article] A long lasting puzzle for －7/7q－ syndrome.2014
- Author(s)
  Honda H, Inaba T
- Journal Title
  
  Oncotarget
  
  Volume: 5 Pages: 7-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640065
[Journal Article] The IL-2/CD25 Axis Maintains Distinct Subsets of Chronic M yeloid Leukemia-initiating Cells.2014
- Author(s)
  Kobayashi CI, Takubo K, Kobayashi H, Nakamura-Ishizu A, Honda H, Kataoka K, Kumano K, Akiyama H, Sudo T, Kurokawa M, Suda T.
- Journal Title
  
  Blood
  
  Volume: 123 Issue: 16 Pages: 2540-2549
- DOI
  10.1182/blood-2013-07-517847
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11J04561, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23689049, KAKENHI-PUBLICLY-25118724, KAKENHI-PROJECT-25640065, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26461170
[Journal Article] CIZ1, a p21 Cip1 /Waf1-interacting protein, functions as a tumor suppressor in vivo2013
- Author(s)
  Nishibe R, Watanabe W, Ueda T, Yamasaki N, Koller R, Wolff L, Honda Z-i, Ohtsubo M, Honda H
- Journal Title
  
  FEBS Lett
  
  Volume: 587 Pages: 1529-1535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390252
[Journal Article] Induction of pluripotent stem cells from primordial germ cells by single reprogramming factors2013
- Author(s)
  Nagamatsu G. Kosaka T, Saito S, Honda H, Takubo K, Kinoshita T, Akiyama H, Sudo T, Horimoto K, Oya M, Suda T
- Journal Title
  
  Stem Cells
  
  Volume: 31 Pages: 479-487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390252
[Journal Article] p130Cas plays important roles in osteoclastic bone resorption2013
- Author(s)
  Nagai Y, Osawa K, Fukushima H, Tamura Y, Aoki K, Ohya K, Yasuda H, Hikiji H, Seta Y, Seo S, Kurokawa M, Kato S, Honda H, Nakamura I, Maki K, Jimi E
- Journal Title
  
  J Bone Miner Res
  
  Volume: 28(12) Pages: 2449-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390252
[Journal Article] Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.2013
- Author(s)
  Nagamachi A
- Journal Title
  
  Cancer Cell
  
  Volume: 24 Issue: 3 Pages: 305-317
- DOI
  10.1016/j.ccr.2013.08.011
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23240125, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23390252, KAKENHI-PROJECT-23689049, KAKENHI-PROJECT-24591397, KAKENHI-PUBLICLY-25118724, KAKENHI-PROJECT-25550030, KAKENHI-PROJECT-25640065
[Journal Article] CIZ1, a p21 (Cip1/Waf1) -interacting protein, functions as a tumor suppressor in vivo2013
- Author(s)
  Nishibe R, Watanabe W, Ueda T, Yamasaki N, Koller R, Wolff L, Honda Z, Ohtsubo M, Honda H
- Journal Title
  
  FEBS Lett
  
  Volume: 587(10) Pages: 1529-1535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590364
[Journal Article] Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 72013
- Author(s)
  Nagamachi A, Matsui H, Asou H, Ozaki Y, Aki D, Takubo K, Suda T, Nakamura T, Wolff L, Honda H, Inaba T
- Journal Title
  
  Cancer Cell
  
  Volume: 24 Pages: 305-317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390253
[Journal Article] Skeletal muscle adaptation 1 in response to mechanical stress in p130Cas-/- mice2013
- Author(s)
  Akimoto T, Okuhira K, Aizawa K, Wada S, Honda H, Fukubayashi T, Uchida T
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 304
- Data Source
  KAKENHI-PROJECT-23390252
[Journal Article] EED mutants impair polycomb repressive complex 2 in myelodysplastic syndrome and related neoplasms.2012
- Author(s)
  Ueda T, Sanada M, Matsui H, Yamasaki N, Honda ZI, Shih LY, Mori H, Inaba T, Ogawa S, Honda H.
- Journal Title
  
  Leukemia.
  
  Volume: 26 Issue: 12 Pages: 2557-60
- DOI
  10.1038/leu.2012.146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591459, KAKENHI-PROJECT-24390242, KAKENHI-PROJECT-24659458
[Journal Article] EED mutants impair polycomb repressive complex 2 in myelodysplastic syndrome and related neoplasms2012
- Author(s)
  Ueda T, Sanada M, Matsui H, Yamasaki N, Honda ZI, Shih LY, Mori H, Inaba T, Ogawa S, Honda H
- Journal Title
  
  Leukemia
  
  Volume: 26(12) Pages: 2557-2560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590364
[Journal Article] Ink4a and Arf are crucial factors in the determination of the cell of origin and the therapeutic sensitivity of Myc-induced mouse lymphoid tumor2012
- Author(s)
  Sugihara E, Shimizu T, Kojima K, Ohishi N, Kai K, Ishizawa J, Nagata K, Hashimoto N, Honda H, Kanno M, Miwa M, Okada S, Andreeff M, Saya H
- Journal Title
  
  Oncogene
  
  Volume: 31 Pages: 2849-2861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390252
[Journal Article] Mouse Samd9l is not a functional paralogue of the human SAMD9, the gene mutated in normophosphataemic familial tumoral calcinosis2012
- Author(s)
  Li Q, Guo H, Matsui H, Honda H, Inaba T, Sundberg JP, Sprecher E, Uitto J
- Journal Title
  
  Exp Dermatol
  
  Volume: 21 Pages: 554-556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390252
[Journal Article] Poly-ADP ribosylation of Miki by tankyrase-1 promotes centrosome maturation2012
- Author(s)
  Ozaki Y, Matsui H, Asou H, Nagamachi A, Aki D, Honda H, Yasunaga S, Takihara Y, Yamamoto T, Izumi S, Ohsugi M, Inaba T
- Journal Title
  
  Mol Cell
  
  Volume: 47 Pages: 694-706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390252
[Journal Article] EED mutants impair polycomb repressive complex 2 in myelodysplastic syndrome and related neoplasms2012
- Author(s)
  Ueda T, Sanada M, Matsui H, Yamasaki N, Honda Zi, Shih LY, Mori H, Inaba T, Ogawa S, Honda H
- Journal Title
  
  Leukemia
  
  Volume: 26 Pages: 2557-2560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390252
[Journal Article] Oncogenic fusion E2A-HLF sensitizes t(17;19)-positive acute lymphoblastic leukemia to TRAIL-mediated apoptosis by upregulating the expression of death receptors2012
- Author(s)
  Zhang X, Kinuko Hirose K, Akahane K, Kuroda I, Honna H, Kagami K, Goi K, Nakamura K, Kobayashi M, Yagita H, Kurosawa H, Look AT, Honda H, Inaba T, Nakazawa S, Sugita K, Endo M, Inukai T
- Journal Title
  
  Leukemia
  
  Volume: 26 Pages: 2483-2493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390252
[Journal Article] Human CD72 splicing isoform responsible for resistance to systemic lupus erythematosus regulates serum immunoglobulin level and is localized in endoplasmic reticulum.2012
- Author(s)
  Hitomi Y, et al.
- Journal Title
  
  BMC Immunol
  
  Volume: 13 Issue: 1 Pages: 72-72
- DOI
  10.1186/1471-2172-13-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390199, KAKENHI-PROJECT-23390063, KAKENHI-PROJECT-23591459, KAKENHI-PROJECT-24590575
[Journal Article] Hemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formation.2011
- Author(s)
  Honda H, Takubo K, Oda H, Kosaki K, Tazaki T, Yamasaki N, Miyazaki K, Moore KA, Honda Zi, Suda T, Lemischka IR.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 108 Pages: 2468-2473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Hemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formation2011
- Author(s)
  Honda H, Takubo K, Oda H, Kosaki K, Tazaki T, Yamasaki N, Miyazaki K, Moore KA, Honda Zi, Suda T, Lemischka IR
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 108 Pages: 2468-2473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390252
[Journal Article] Hemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formation.2011
- Author(s)
  Honda H, Takubo K, Oda H, Kosaki K, Tazaki T, Yamasaki N, Miyazaki K, Moore KA, Honda ZI, Suda T, Lemischka IR.
- Journal Title
  
  Proc Natl Acad Sci USA 108(6)
  
  Pages: 2468-2473
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Cas-L regulates myeloid cell motility and suppresses progression of leukemia induced by p210Bcr/Abl2011
- Author(s)
  Seo S, Nakamoto T, Takeshita M, Lu J, Sato T, Suzuki T, Kamikubo Y, Ichikawa M, Noda M, Ogawa S, Honda H, Oda H, Kurokawa M
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 2109-2117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390252
[Journal Article] Hemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formation2011
- Author(s)
  Honda H(他10名 )
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 108 Issue: 6 Pages: 2468-2473
- DOI
  10.1073/pnas.1003403108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23591459
[Journal Article] The Samd9L gene : transcriptional regulation and tissue-specific expression in mouse development2011
- Author(s)
  Jiang Q, Quaynor B, Sun A, Li Q, Matsui H, Honda H, Inaba T, Sprecher E, Uitto J
- Journal Title
  
  J Invest Dermatol
  
  Volume: 131 Pages: 1428-1434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390252
[Journal Article] pl30Cas plays essential roles in liver development by regulating sinusoidal endothelial cell fenestration.2010
- Author(s)
  Tazaki T, Sasaki, Uto K, Yamasaki N, Tashiro S, Sakai R, Tanaka M, Oda H, HondaZi, Honda H.
- Journal Title
  
  Hepatology
  
  Volume: 52 Pages: 1089-1099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] The role of the basic helix-loop-helix transcription factor Dec1 in the regulatory T cells.2010
- Author(s)
  Miyazaki K, Miyazaki M, Guo Y, Yamasaki N, Kanno M, Honda Zi, Oda H, Kawamoto H, Honda H.
- Journal Title
  
  Journal of Immunology
  
  Volume: 385 Pages: 7330-7339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] A 5' untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model.2010
- Author(s)
  Nagamachi A, Htun PW, Ma F, Miyazaki K, Yamasaki N, Kanno M, Inaba T, Honda Zi, Okuda T, Oda H, Tsuji K, Honda H.
- Journal Title
  
  Dev Biol 345
  
  Pages: 226-236
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia.2010
- Author(s)
  Yamasaki N, Miyazaki K, Nagamachi A, Koller R, Oda H, Miyazaki M, Sasaki T, Honda Zi, Wolff L, Inaba T, Honda H.
- Journal Title
  
  Oncogene 29
  
  Pages: 1963-1975
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] The role of the basic helix-loop-helix transcription factor Dec1 in the regulatory T cells.2010
- Author(s)
  Miyazaki K, Miyazaki M, Guo Y, Yamasaki N, Kanno M, Honda Zi, Oda H, Kawamoto H, Honda H.
- Journal Title
  
  J Immunol 385(12)
  
  Pages: 7330-7339
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] A 5' untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model.2010
- Author(s)
  Nagamachi A., Htun P.W., Ma F., Miyazaki K., Yamasaki N., Kanno M., Inaba T., Honda Z.I., Okuda T., Oda H., Tsuji K., Honda H.
- Journal Title
  
  Dev Biol. 345
  
  Pages: 226-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390271
[Journal Article] p130Cas plays essential roles in liver development by regulating sinusoidal endothelial cell fenestration.2010
- Author(s)
  Tazaki T, Sasaki T, Uto K, Yamasaki N, Tashiro S, Sakai R, Tanaka M, Oda H, Honda Zi, Honda H.
- Journal Title
  
  Hepatology 52
  
  Pages: 1089-1099
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] A 5' untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model.2010
- Author(s)
  Nagamachi A, Htun P W, Ma F, Miyazaki K, Yamasaki N, Kanno M, Inaba T, Honda Zi, Okuda T, Oda H, Tsuji K, Honda H.
- Journal Title
  
  Developmental Biology
  
  Volume: 345 Pages: 226-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Identification of Zfp521/ZNF521 as acooperative gene for E2A-HLF to develop acute B-lineage leukemia.2010
- Author(s)
  Yamasaki N., Miyazaki K., Nagamachi A., Koller R., Oda H., Miyazaki M., Sasaki T., Honda Z, Wolff L., Inaba T., Honda H.
- Journal Title
  
  Oncogene 29
  
  Pages: 1963-1975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390271
[Journal Article] Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia.2010
- Author(s)
  Yamasaki N, Miyazaki K, Nagamachi A, Koller R, Oda H, Miyazaki M, Sasaki T, Honda Zi, Wolff L, Inaba T, Honda H.
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 1963-1975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.2009
- Author(s)
  Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S.
- Journal Title
  
  Nature 460
  
  Pages: 904-908
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Haploinsufficiency and acquired loss of Bcl11b and H2AX induced blast crisis of chronic myelogenous leukemia in a transgenic mouse model.2009
- Author(s)
  Nagamachi A, 7名, Honda H.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 1219-1226
- NAID
  10027191952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Elevated intraocular pressure, optic nerve atrophy, and impaired retinal development in ODAG transgenic mice.2009
- Author(s)
  Sasaki T, Watanabe W, Muranishi Y, Kanamoto T, Aihara M, Miyazaki K, Tamura H, Saeki T, Oda H, Souchelnytskyi N, Souchelnytskyi S, Hirohiko A, Honda Zi, Furukawa T, Mishima HK, Kiuchi Y, Honda H.
- Journal Title
  
  Invest Ophthalmol Vis Sci 50
  
  Pages: 242-248
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Enhanced expression of p210BCR/ABL and aberrant expression of Zfp423/ZNF423 induce blast crisis of chronic myelogenous leukemia.2009
- Author(s)
  Miyazaki K, 13名, Honda H.
- Journal Title
  
  Blood 27
  
  Pages: 4702-4710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Haploinsufficiency and acquired loss of Bcl11b and H2AX induced blast crisis of chronic myelogenous leukemia in a transgenic mouse model.2009
- Author(s)
  Nagamachi A, Yamasaki N, Miyazaki K, Oda H, Miyazaki M, Honda Zi, Kominami R, Inaba T, Honda H.
- Journal Title
  
  Cancer Sci 100
  
  Pages: 1219-1226
- NAID
  10027191952
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Enhanced expression of p210BCR/ABL and aberrant expression of Zfp423/ZNF423 induce blast crisis of chronic myelogenous leukemia.2009
- Author(s)
  Miyazaki K, Yamasaki N, Oda H, Kuwata T, Kanno Y, Miyazaki M, Komeno Y, Kitaura J, Honda Zi, Warming S, Jenkins NA, Copeland NG, Kitamura T, Nakamura T, Honda H.
- Journal Title
  
  Blood 113
  
  Pages: 4702-4710
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Haploinsufficiency and acquired loss of Bcl11b and H2AX induced blast crisis of chronic myelogenous leukemia in a transgenic mouse model.2009
- Author(s)
  Nagamachi A., Yamasaki N., Miyazaki K., Oda H., Miyazaki M., Honda Z-i., Kominami R., Inaba T., Honda H.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 1219-1226
- NAID
  10027191952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390271
[Journal Article] Overexpression of ocular development-associated gene (ODAG) in the eye induced elevated intraocular pressure, optic nerve atrophy, and impaired retinal development.2009
- Author(s)
  Sasaki T, Watanabe W, Muranishi Y, Kanamoto T, Aihara M, Miyazaki K, Tamura H, Saeki T, Oda H, Souchelnytskyi N, Souchelnytskyi S, Hirohiko A, Honda Z-i, Furukawa T, Mishima HK, Kiuchi Y, Honda H
- Journal Title
  
  Invest Ophthalmol Vis Sci. 50
  
  Pages: 242-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Identification of CENP-V as a novel microtubule-associating molecule that activates Src family kinases through SH3 domain interaction.2009
- Author(s)
  Honda Zi, Suzuki T, Honda H.
- Journal Title
  
  Genes Cells 14
  
  Pages: 1383-1394
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.2009
- Author(s)
  Sanada M, 6名, Honda H, 20名, Ogawa S.
- Journal Title
  
  Nature 100
  
  Pages: 904-908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Overexpression/enhanced kinase activity of BCR/ABL and altered expression of Notch1 induced acute leukemia in p210BCR/ABL transgenic mice.2008
- Author(s)
  Mizuno T, Yamasaki N, Miyazaki K, Tazaki T, Koller R, Oda H, Honda Zi, Ochi M, Wolff L, Honda H.
- Journal Title
  
  Oncogene 27
  
  Pages: 3465-3474
- NAID
  120001192643
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Functional analysis of Src homology 3-encoding exon (exon 2) of p130Cas in primary fib roblasts derived from exon 2-specific knockout mice.2008
- Author(s)
  Tazaki T, Honda Z, 他
- Journal Title
  
  Genes Cells. 13
  
  Pages: 145-57
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591101
[Journal Article] Overexpression/enhanced kinase activity of BCR/ABL and altered expression of Notch 1 induced acute leukemia in p210BCR/ABL transgenic mice.2008
- Author(s)
  Mizuno T, Honda Z 他
- Journal Title
  
  Oncogene in press
- NAID
  120001192643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591101
[Journal Article] Functional analysis of Src homology 3-encoding exon (exon 2) of p 130Cas in primary fibroblasts derived from exon 2-specific knockout mice.2008
- Author(s)
  Tazaki T, Miyazaki K, Hiyama E, Nakamoto T, Sakai R, Yamasaki N, Honda Z-i, Noda M, Miyasaka N, Sueda T, and Honda H.
- Journal Title
  
  Genes Cells 13
  
  Pages: 145-157
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591064
[Journal Article] Overexpression/enhanced kinase activity of BCR/ABL and altered expression of Notchl induced acute leukemia in p210BCR/ABL transgenic mice2008
- Author(s)
  Mizuno T, Honda Z, et. al.
- Journal Title
  
  Oncogene
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591101
[Journal Article] Overexpression / enhanced kinase activity of BCR / ABL and altered expression of Notchl induced acute leukemia in p210BCR / ABL ransgenic mice.2008
- Author(s)
  Mizuno T, Honda Z, 他
- Journal Title
  
  Oncogene (In press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591101
[Journal Article] Successful treatment with infliximab of refractory rheumatoid arthritis in a male with ‘GDF5 brachydactyly'.2008
- Author(s)
  Suzuki T, Honda Z.
- Journal Title
  
  Rheumatol Int. 28
  
  Pages: 201-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591101
[Journal Article] Functional analysis of Src homology 3-encoding exon (exon 2) of p130Cas in primary fibroblasts derived from exon 2-specific knockout mice2008
- Author(s)
  Tazaki, T., Miyazaki, K., Hiyama, E., Nakamoto, T., Sakai, R., Yamasaki, N., Honda, Z-i., Noda, M., Miyasaka, N., Sueda, T., Honda, H
- Journal Title
  
  Genes Cells 13
  
  Pages: 145-157
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Journal Article] Pre-TCR-induced thymocyte proliferation is epigenetically maintained through BMI-1-mediated p19Arf repression.2008
- Author(s)
  Miyazaki M, Miyazaki K, Itoi M, Katoh Y, Guo Y, Kanno R, Katoh-Fukui Y, Honda H, Amagai T, van Lohuizen M, Kawamoto H, Kanno M.
- Journal Title
  
  Immunity 28
  
  Pages: 231-245
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Pre-TCR-induced thymocyte proliferation is epigenetically maintained through BMI-1-mediated p19Arf repression.2008
- Author(s)
  Miyazaki M, Miyazaki K, Itoi M, Katoh Y, Guo Y, Kanno R, Katoh-Fukui Y, Honda H, Amagai T, van Lohuizen M, Kawamoto H, and Kanno M.
- Journal Title
  
  Immunity 28
  
  Pages: 231-245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591064
[Journal Article] Overexpression/enhanced kinase activity of BCR/ABL and altered expression of Notch1 induced acute leukemia in p210BCR/ABL transgenic mice.2008
- Author(s)
  Mizuno T, Yamasaki N, Miyazaki K, Tazaki T, Koller R, Oda H, Honda Z-i, Ochi M, Wolff L, and Honda H.
- Journal Title
  
  Oncogene (印刷中)
- NAID
  120001192643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591064
[Journal Article] Successful treatment with infliximab of refractory rheumatoid arthritis in amale with'GDF5 brachydactyly'.2008
- Author(s)
  Suzuki T, Honda Z.
- Journal Title
  
  Rheumatology Int 28
  
  Pages: 201-3
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591101
[Journal Article] Functional analysis of Src homology 3-encoding exon(exon 2) of p 130Cas in primary fibroblasts derived from exon 2-specific knockout mice2008
- Author(s)
  Takaki T, Honda Z, et. al.
- Journal Title
  
  Genes Cells 13(2)
  
  Pages: 145-57
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591101
[Journal Article] Functional analysis of Src homology 3-encoding exon (exon 2) of p130Cas in primary fibroblasts derived from exon 2-specific knockout mice.2008
- Author(s)
  Tazaki T, Miyazaki K, Hiyama E, Nakamoto T, Sakai R, Yamasaki N, Honda Zi, Noda M, Miyasaka N, Sueda T, Honda H.
- Journal Title
  
  Genes Cells 13
  
  Pages: 145-157
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Pre-TCR-induced thymocyte proliferation is epigenetically maintained through BMI-1-mediated p 19Arf repression.2008
- Author(s)
  Miyazaki M, Miyazaki K, Itoi M, Katoh Y, Guo Y, Kanno R, Katoh-Fukui Y, Honda H, Amagai T, van Lohuizen M, Kawamoto H, and Kanno M.
- Journal Title
  
  Immunity 28
  
  Pages: 231-245
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591064
[Journal Article] Functional analysis of Src homology 3-encoding exon (exon 2) of p130Cas in primary fibroblasts derived from exon 2-specific knockout mice.2008
- Author(s)
  Tazaki T, Miyazaki K, Hiyama E, Nakamoto T, Sakai R, Yamasaki N, Honda Z-i, Noda M, Miyasaka N, Sueda T, and Honda H.
- Journal Title
  
  Genes Cells 13
  
  Pages: 145-157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591064
[Journal Article] Overexpression/enhanced kinase activity of BCR/ABL and altered expression of Notchl induced acute leukemia in p210BCR/ABL transgenic mice.2008
- Author(s)
  Mizuno T, Yamasaki N, Miyazaki K, Tazaki T, Koller R, Oda H, Honda Z-i, Ochi M, Wolff L, Honda H.
- Journal Title
  
  Oncogene 27
  
  Pages: 3465-3474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591126
[Journal Article] Functional analysis of Src homology 3-encoding exon (exon 2) of p130Cas in primary fibroblasts derived from exon 2-specific knockout mice.2008
- Author(s)
  Tazaki T, Honda Z 他
- Journal Title
  
  Genes Cells. 13
  
  Pages: 145-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591101
[Journal Article] Pre-TCR-induced thymocyte proliferation is epigenetically maintained through BMI-1-mediated p19Arf repression2008
- Author(s)
  Miyazaki, M., Miyazaki, K., Itol, M., Katoh, Y., Guo, Y., Kanno, R., Katoh-Fukui, Y., Honda, H., Amagai, T., van, Lohuizen, M., Kawamoto, H., Kanno, M
- Journal Title
  
  Immunity 28
  
  Pages: 231-245
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Journal Article] Successful treatment with infliximab of refractory rheumatoid arthritis in a male with 'GDF5 brachydactyly'2007
- Author(s)
  Suzuki T Honda Z
- Journal Title
  
  Rheumatol Int 28(2)
  
  Pages: 201-3
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591101
[Journal Article] 疾患モデルを用いた腫瘍発症の分子機構、造血器腫瘍(基礎・臨床領域における最新の研究動向)2007
- Author(s)
  本田浩章
- Journal Title
  
  日本臨床増刊号(日本臨床社) 増刊号
  
  Pages: 24-33
- Data Source
  KAKENHI-PROJECT-18591064
[Journal Article] Role of B cell inhibitory receptor polymorphisms in systemic lupus erythematosus : a negative times a negative makes a positive.2006
- Author(s)
  土屋尚之, 本田善一郎他
- Journal Title
  
  Journal of Human Genetics 51
  
  Pages: 741-750
- NAID
  10018765367
- Data Source
  KAKENHI-PROJECT-18591101
[Journal Article] Fcepsilon-and Fcgamma-receptor signaling in diseases.2006
- Author(s)
  本田善一郎
- Journal Title
  
  Springer Seminar in Immunopathology 28
  
  Pages: 365-375
- Data Source
  KAKENHI-PROJECT-18591101
[Journal Article] Role of B cell inhibitory receptor polymorphisms in systemic lupus erythematosus : a negative times a negative makes a positive2006
- Author(s)
  Tsuchiya N, Honda Z
- Journal Title
  
  J Hum Genet 51(9)
  
  Pages: 741-50
- NAID
  10018765367
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591101
[Journal Article] 後天性に誘導可能に目的遺伝子を発現する白血病モデルマウスの作製2006
- Author(s)
  本田浩章
- Journal Title
  
  放射線生物研究 41・3
  
  Pages: 255-263
- NAID
  40015127373
- Data Source
  KAKENHI-PROJECT-18591064
[Journal Article] Fcepsilon- and Fcgamma-receptor signaling in diseases2006
- Author(s)
  Honda Z
- Journal Title
  
  Springer Semin Immunopathol 28(4)
  
  Pages: 365-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591101
[Journal Article] Fc gamma RIIB Ile232Thr transmembrane polymorphism -----2005
- Author(s)
  Kono H., -----., *Honda Z.
- Journal Title
  
  Human Molecular Genetics 14(19)
  
  Pages: 2881-2892
- Data Source
  KAKENHI-PROJECT-16590976
[Journal Article] Fc gamma RIIB Ile232Thr transmembrane polymorphism-----2005
- Author(s)
  Kono H., -----., *Honda Z.
- Journal Title
  
  Human Molecular Genetics 14(19)
  
  Pages: 2881-2892
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590976
[Journal Article] CD72 polymorphisms associated with alternative---2004
- Author(s)
  Hitomi Y., ----Honda Z, Tolunaga K.
- Journal Title
  
  Human Molecular Genetics 13(23)
  
  Pages: 2907-2917
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590976
[Journal Article] CD72 polymorphisms associated with alternative splicing modify susceptibility to human systemic lupus erythematosus through epistatic interaction with FCGR2B2004
- Author(s)
  Hitomi Y, Honda, Z他
- Journal Title
  
  Hum.Mol.Genet. 13・23
  
  Pages: 2907-2917
- Data Source
  KAKENHI-PROJECT-16590976
[Journal Article] 「研究成果報告書概要(欧文)」より2004
- Author(s)
  Hitomi Y, ----, Z.Honda, K Tokunaga.
- Journal Title
  
  Human Molecular Genetics 13(23)
  
  Pages: 2907-2917
- Data Source
  KAKENHI-PROJECT-16590976
[Journal Article] Overexpression/enhanced kinase activity of BCR/ABL and altered expression of Notch1 induced acute leukemia in p210BCR/ABL transgenic mice.
- Author(s)
  Mizuno T, Yamasaki N, Miyazaki K, Tazaki T, Koller R, Oda H, Honda Z-i, Ochi M, Wolff L, and Honda H.
- Journal Title
  
  Oncogene (印刷中)
- NAID
  120001192643
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591064
[Journal Article] Overexpression/enhanced kinase activity of BCR/ABL and altered expression of Notch 1 induced acute leukemia in p210BCR/ABL transgenic mice
- Author(s)
  Mizuno, T., Yamasaki, N., Miyazaki, K., Tazaki, T., Koller, R., Oda, H., Honda, Z-i., Ochi, M., Wolff, L., Honda, H
- Journal Title
  
  Oncogene (in press)
- NAID
  120001192643
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Journal Article] The Samd9L Gene : Transcriptional Regulation and Tissue-Specific Expression in Mouse Development.
- Author(s)
  Jiang, Q., Quaynor, B., Sun, A., Li, Q., Matsui, H., Honda, H., Inaba, T., Sprecher, E., Uitto J.
- Journal Title
  
  J Invest Dermatol in press
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] Prostate cancer with histone modifier UTX mutations can benefit from olaparib.2023
- Author(s)
  Muramoto N, Iwasaki M, Sera Y, Ide H, Horie S, Honda H.
- Organizer
  European Society for Medical Oncology Asia Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27442
[Presentation] The contribution of functional loss of epigenetic factors, UTX and UTY, to prostate cancer development.2023
- Author(s)
  Honda H.
- Organizer
  Turuoka Conference “Roles of epigenetic factors in cancer”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27442
[Presentation] 破骨細胞骨吸収制御因子のshRNAライブラリースクリーニングによる網羅的探索とその候補遺伝子の機能解析2021
- Author(s)
  久木田明子, 平田寛人, 蒲原麻菜, 村山雅俊, 本田浩章, 馬渡正明
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22546
[Presentation] 破骨細胞骨吸収制御因子のshRNAライブラリースクリーニングによる網羅的探索とその候補遺伝子の機能解析2021
- Author(s)
  久木田明子, 平田寛人, 蒲原麻菜, 村山雅俊, 本田浩章, 馬渡正明
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03693
[Presentation] Wnt5a plays a critical role in anal opening at an early stage of embryo development2021
- Author(s)
  Mitsuyuki Nakata, Hiroaki Honda, Atsushi Iwama, Keita Teru1, Shugo Komatsu, Ryohei Shibata, Tomoro Hishiki
- Organizer
  34th International Symposium on Pediatric Surgical Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22546
[Presentation] ヒストン修飾因子UTXは老化関連遺伝子を制御することにより造血系維持に関与する2021
- Author(s)
  世良康如, 中田雄一郎, 上田健, 山崎憲政, 小出周平, 小林央, 池田健一郎, 小畠浩平, 岩崎正幸, 小田秀明, 金井昭教, 長町安希子, 稲葉俊哉, 外丸祐介, 一戸辰夫, 小泉美穂, 宮川佳彦, 本田善一郎, 岩間厚志, 須田年生, 田久保圭誉, 本田浩章
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03693
[Presentation] ヒストン修飾因子UTXは老化関連遺伝子を制御することにより造血系維持に関与する2021
- Author(s)
  世良康如, 中田雄一郎, 上田健, 山崎憲政, 小出周平, 小林央, 池田健一郎, 小畠浩平, 岩崎正幸, 小田秀明, 金井昭教, 長町安希子, 稲葉俊哉, 外丸祐介, 一戸辰夫, 小泉美穂, 宮川佳彦, 本田善一郎, 岩間厚志, 須田年生, 田久保圭誉, 本田浩章
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22546
[Presentation] Wnt5a plays a critical role in anal opening at an early stage of embryo development2021
- Author(s)
  Mitsuyuki Nakata, Hiroaki Honda, Atsushi Iwama, Keita Teru1, Shugo Komatsu, Ryohei Shibata, Tomoro Hishiki
- Organizer
  34th International Symposium on Pediatric Surgical Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03693
[Presentation] 膀胱がん発症におけるヒストン修飾因子KDM6Aの機能解析2020
- Author(s)
  本田浩章
- Organizer
  国立がんセンター鶴岡カンファランス
- Invited
- Data Source
  KAKENHI-PROJECT-19H03693
[Presentation] 2.ヒストン修飾因子UTXは老化関連遺伝子を制御することにより造血形維持に関与する2020
- Author(s)
  世良康如, 本田浩章
- Organizer
  第1回レドックスR&D戦略研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22546
[Presentation] 2.ヒストン修飾因子UTXは老化関連遺伝子を制御することにより造血形維持に関与する2020
- Author(s)
  世良康如, 本田浩章
- Organizer
  第1回レドックスR&D戦略研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03693
[Presentation] 1.膀胱がん発症におけるヒストン修飾因子KDM6Aの機能解析2020
- Author(s)
  本田浩章
- Organizer
  国立がんセンター鶴岡カンファランス
- Invited
- Data Source
  KAKENHI-PROJECT-19K22546
[Presentation] ヒストン脱メチル化酵素JMJD3が白血病を誘導させるエピゲノム制御および蛋白質相互作用の解明2019
- Author(s)
  中田雄一郎、上田健、金井昭教、世良康如、竹田浩之、神沼修、本田浩章
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K22546
[Presentation] ヒストンの修飾因子UTXの脳特異的な欠損マウスの解析2019
- Author(s)
  小泉美穂、三田村佳勇、世良康如、本田浩章、衛藤光、岸雄介、藤平篤志
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19H03693
[Presentation] MLL遺伝子再構成を伴う急性骨髄性白血病幹細胞における15－PGDHの役割2019
- Author(s)
  岩崎正幸、本田浩章、大里元美、Michael Cleary
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22546
[Presentation] MLL遺伝子再構成を伴う急性骨髄性白血病幹細胞における15－PGDHの役割2019
- Author(s)
  岩崎正幸、本田浩章、大里元美、Michael Cleary
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03693
[Presentation] ヒストン脱メチル化酵素JMJD3が白血病を誘導させるエピゲノム制御および蛋白質相互作用の解明2019
- Author(s)
  中田雄一郎、上田健、金井昭教、世良康如、竹田浩之、神沼修、本田浩章
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03693
[Presentation] ヒストンの修飾因子UTXの脳特異的な欠損マウスの解析2019
- Author(s)
  小泉美穂、三田村佳勇、世良康如、本田浩章、衛藤光、岸雄介、藤平篤志
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K22546
[Presentation] Analysis of pathogenic mechanisms and development of therapeutic approaches using mouse cancer models2016
- Author(s)
  Hiroaki Honda
- Organizer
  第75回日本癌学会総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-26293227
[Presentation] Jmjd3コンディショナルノックインマウスにおける白血病感受性亢進機構の解析2016
- Author(s)
  池田健一郎、上田健、長町安希子、山崎憲政、中田雄一郎、世良康如、小畠浩平、稲葉俊哉、本田浩章
- Organizer
  第75回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-26293227
[Presentation] AMLの分子機構2016
- Author(s)
  本田浩章
- Organizer
  第78回日本血液学学会総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-26293227
[Presentation] EED変異体によるPRC2活性化障害の造血器腫瘍発症における役割2016
- Author(s)
  上田健、中田雄一郎、長町安希子、山崎憲政、金井昭教、松井啓隆、稲葉俊哉、本田浩章
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター (宮城)
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460391
[Presentation] ヒストン脱メチル化酵素Fbxl10の白血病における機能解析2015
- Author(s)
  上田　健、長町安希子、中田雄一郎、山崎憲政、稲葉俊哉、本田浩章
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学大会　合同大会（ポスター)
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460391
[Presentation] Haploinsufficiency of Eed enhances to tumor susceptibility and develop leukemia with overexpression of Evi12015
- Author(s)
  Kenichiro Ikeda, Takeshi Ueda, Akiko Nagamachi, Norimasa Yamasaki, Yuichiro Nakata, Toshiya Inaba, Hiroaki Honda
- Organizer
  The 74th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2015-09-29
- Data Source
  KAKENHI-PROJECT-26293227
[Presentation] Functional analysis of UTX, a histone demethylase for H3K27, in normal hematopoiesis and hematologic malignancies2015
- Author(s)
  Yasuyuki Sera, Takeshi Ueda, Yuichiro Nakata, Ken-ichiro Ikeda, Norimasa Yamasaki, Hideaki Oda, Zen-ichiro Honda and Hiroaki Honda
- Organizer
  The 77th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Kanazawa
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26293227
[Presentation] Role of disease-related EED Ile363Met mutant in embryonic development and tumorigenesis2014
- Author(s)
  Takeshi Ueda, Masashi Sanada, Hirotaka Matsui, Norimasa Yamasaki, Zen-ichiro Honda, Lee-Yung Shih, Hiraku Mori, Toshiya Inaba, Seishi Ogawa, and Hiroaki Honda
- Organizer
  日本血液学会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-23390252
[Presentation] Analysis of leukemogenic mechanisms by deregulated methylation of histone H3K272014
- Author(s)
  Honda H
- Organizer
  The 73rd Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Tokyo
- Year and Date
  2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-26293227
[Presentation] Disease-associated EED Ile363Met mutation increases susceptibility to hematologic malignancies2014
- Author(s)
  上田　健, 長町安希子,中田雄一郎, 山崎憲政, 松井啓隆, 本田浩章
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-26460391
[Presentation] Identification of interacting partners for MAP kinase-interacting kinase 12013
- Author(s)
  上田健, 福永理己郎, Roumiana Alexandrova, Theo Goh, Tak W. Mak, 本田浩章
- Organizer
  第86回日本生化学会
- Place of Presentation
  横浜
- Year and Date
  2013-09-11
- Data Source
  KAKENHI-PROJECT-23590364
[Presentation] ヒストン脱メチル化酵素Fbxl10の脱制御による白血病発症機構の解析2013
- Author(s)
  本田浩章
- Organizer
  新学術領域がん支援冬期シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390252
[Presentation] Role of disease-related EED Ile363Met mutant in embryonic development and tumorigenesis2013
- Author(s)
  Takeshi Ueda, Masashi Sanada, Hirotaka Matsui, Norimasa Yamasaki, Zen-ichiro Honda, Lee-Yung Shih, Hiraku Mori, Toshiya Inaba, Seishi Ogawa, Hiroaki Honda
- Organizer
  日本血液学会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-25640065
[Presentation] 遺伝子改変マウスを用いた造血器腫瘍関連EED Ile363Met変異体の解析2013
- Author(s)
  上田健, 真田昌, 松井啓隆, 山崎憲政, 本田善一郎, 森啓, LEE-YUNG SHIH, 稲葉俊哉, 小川誠司, 本田浩章
- Organizer
  第75回日本血液学会
- Place of Presentation
  札幌
- Year and Date
  2013-10-12
- Data Source
  KAKENHI-PROJECT-23590364
[Presentation] MDSで同定されたポリコローム複合体構成因子EEDの機能欠失型変異体の解析2012
- Author(s)
  上田健, 真田晶, 松井啓隆, 山崎憲政, 本田善一郎, 森啓, LEE-YUNG SHIH 稲葉俊哉, 小川誠司, 本田浩章
- Organizer
  第74回日本血液学会
- Place of Presentation
  京都
- Year and Date
  2012-10-19
- Data Source
  KAKENHI-PROJECT-23390252
[Presentation] MDSで同定されたポリコーム複合体PRC2構成因子EEDの機能欠失型変異体の解析2012
- Author(s)
  上田健, 真田昌, 松井啓隆, 山崎憲政, 本田善一郎, 森啓, LEE-YUNG SHIH, 稲葉俊哉, 小川誠司, 本田浩章
- Organizer
  第74回日本血液学会
- Place of Presentation
  京都
- Year and Date
  2012-10-19
- Data Source
  KAKENHI-PROJECT-23590364
[Presentation] MDSで同定されたポリコローム複合体構成因子EEDの機能欠失型変異体の解析2012
- Author(s)
  上田健,真田晶,松井啓隆,山崎憲政,本田善一郎,森啓, LEE-YUNG SHIH稲葉俊哉,小川誠司,本田浩章
- Organizer
  第74回日本血液学会
- Place of Presentation
  京都
- Year and Date
  2012-10-19
- Data Source
  KAKENHI-PROJECT-23591459
[Presentation] 骨髄異形成症候群におけるポリコローム複合体PRC構成因子EDDの機構欠失型変異2011
- Author(s)
  上田健, 真田晶, 松井啓隆, 山崎憲政, 本田善一郎, 森啓, LEE-YUNG SHIH, 稲葉俊哉, 小川誠司, 本田浩章
- Organizer
  第73回日本血液学会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23390252
[Presentation] 骨髄異形成症候群におけるポリコーム複合体PRC2構成因子EEDの機能欠失型変異2011
- Author(s)
  上田健, 真田昌, 松井啓隆, 山崎憲政, 本田善一郎, 森啓, LEE-YUNG SHIH, 稲葉俊哉, 小川誠司, 本田浩章
- Organizer
  第73回日本血液学会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23590364
[Presentation] Eed mutations impairing polycomb repressive complex 2 function in myelodysplastic syndrome2011
- Author(s)
  上田健、真田昌、松井啓隆、山崎憲政、本田善一郎、Lee-Yung Shih、森啓、稲葉俊哉、小川誠司、本田浩章
- Organizer
  日本血液学
- Place of Presentation
  名古屋
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-23390252
[Presentation] Different mechanisms through which Samd9L, a-7/7q-responsible gene, contributes to leukemogenesis2011
- Author(s)
  長町安希子、松井啓隆、尾崎佑子、山崎憲政、小田秀明、稲葉俊哉、本田浩章
- Organizer
  日本血液学
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23390252
[Presentation] Analysis of leukemogenic mechanisms induced by deregulation of a histone demethylase, Fbx1102011
- Author(s)
  本田浩章
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜(招待講演)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-23390252
[Presentation] 横断性脊髄炎を呈した全身性エリテマトーデスの一例2011
- Author(s)
  津久井大輔,岡本明子,大久保麻衣,浅子来美,本田善一郎,河野肇,滝川一
- Organizer
  第599回日本内科学会関東地方会
- Place of Presentation
  東京
- Year and Date
  2011-04-14
- Data Source
  KAKENHI-PROJECT-23591459
[Presentation] -7/7q-責任遺伝子候補 Samd9L2011
- Author(s)
  長町安希子, 松井啓隆, 尾崎裕子, 山崎憲政, 小田秀明 , 稲葉俊哉 , 本田浩章
- Organizer
  第73回日本血液学会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-23390252
[Presentation] Titan (Samd9L), a candidate 7q-responsiblegene product, promotes degradation of cytokine receptors.2010
- Author(s)
  松井啓隆, 長町安希子, 尾崎佑子, 麻生博也, 本田浩章, 稲葉俊哉
- Organizer
  第72回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] 7q-欠損白血病におけるEvil, Fbxl10の関与2010
- Author(s)
  長町安希子, 松井啓隆, 安藝大輔, 尾崎佑子, 麻生博也, 山崎憲政, 小田秀明, 稲葉俊哉, 本田浩章
- Organizer
  第51回原子爆弾後障害研究会
- Place of Presentation
  長崎
- Year and Date
  2010-06-06
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] 7q欠失責任遺伝子候補Titanによるサイトカイン受容体分解制御2010
- Author(s)
  松井啓隆, 長町安希子, 尾崎佑子, 安藝大輔, 麻生博也, 本田浩章, 稲葉俊哉
- Organizer
  第51回原子爆弾後障害研究会
- Place of Presentation
  長崎
- Year and Date
  2010-06-06
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] Titan (Samd9L),a candidate-7/7q-responsible gene product, downregulates cytokine signals by facilitating formation of early endosomes.2010
- Author(s)
  松井啓隆, 長町安希子, 尾崎佑子, 麻生博也, 本田浩章, 稲葉俊哉
- Organizer
  第52回米国血液学会総会
- Place of Presentation
  米国オーランド
- Year and Date
  2010-12-06
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] Titan (Samd9L), a candidate 7q- responsible gene product, promotes degradation of cytokine receptors.2010
- Author(s)
  松井啓隆, 長町安希子, 尾崎佑子, 麻生博也, 本田浩章, 稲葉俊哉
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] Deregulated expression of Fbxl10, a histone demethylase, contributes to leukemia development.2010
- Author(s)
  Ueda T, Inagaki M, Nagamachi A, Yamasaki N, Matsui H, Takubo K, Konuma T, Suda T, Iwama A, Inaba T, Honda H
- Organizer
  第72回日本血液学会
- Place of Presentation
  横浜
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-20591126
[Presentation] 造血細胞におけるWnt5aの欠失はp210BCR/ABLによって引き起こされるCMLを増悪させる2010
- Author(s)
  稲垣舞子、小山浩史、菊池章、本田浩章
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20591126
[Presentation] Unique Gain-of-Function of Mutated c-CBL Tumor Suppresor in Myeloid Neoplasms.2009
- Author(s)
  Sanada M, 5名本田浩章, 14名, Ogawa S.
- Organizer
  51th Annual Meeting of American Society of Hematology
- Place of Presentation
  New Orleans, USA
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20591126
[Presentation] ヒストン脱メチル化酵素Fbxl10の7q-AML/MDS発症過程への関与2009
- Author(s)
  長町安希子, 松井啓隆, 安藝大輔, 尾崎佑子, 麻生博也, 宮崎和子, 山崎憲政, 小田秀明, 稲葉俊哉, 本田浩章
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] 7q-欠失責任遺伝子候補Titanの機能解析:アクチンリモデリング活性化と古典的wnt経路抑制による造血細胞制御2009
- Author(s)
  松井啓隆, 長町安希子, 尾崎佑子, 安藝大輔, 麻生博也, 本田浩章, 稲葉俊哉
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] 白血病責任遺伝子Mikiによる細胞内小胞輸送の制御2009
- Author(s)
  安藝大輔, 竹村幸敏, 長町安希子, 尾崎佑子, 松井啓隆, 麻生博也, 稲葉俊哉, 本田浩章
- Organizer
  第50回原子爆弾後障害研究会
- Place of Presentation
  広島
- Year and Date
  2009-06-07
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] 7q欠失責任遺伝子候補Titanの機能解析:アクチンリモデリング活性化と古典的wnt経路抑制による造血細胞制御2009
- Author(s)
  松井啓隆, 長町安希子, 尾崎佑子, 安藝大輔, 麻生博也, 本田浩章, 稲葉俊哉
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] ヒストン脱メチル化酵素Fbxl10の7q- AML/MDS発症過程への関与2009
- Author(s)
  長町安希子, 8名, 本田浩章
- Organizer
  日本血液学会年会
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20591126
[Presentation] 7q欠失責任遺伝子候補Titanはアクチンリモデリングを制御する2009
- Author(s)
  松井啓隆, 長町安希子, 尾崎佑子, 安藝大輔, 麻生博也, 本田浩章, 稲葉俊哉
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2009-10-29
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] 7q欠失責任遺伝子候補Titanの機能解析:アクチンリモデリング活性化,および古典的wnt経路の抑制による造血細胞の制御2009
- Author(s)
  松井啓隆, 長町安希子, 尾崎佑子, 安藝大輔, 麻生博也, 本田浩章, 稲葉俊哉
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] 7q欠失責任遺伝子候補Titanはアクチンリモデリングを制御する2009
- Author(s)
  松井啓隆, 長町安希子, 尾崎佑子, 安藝大輔, 麻生博也, 稲葉俊哉, 本田浩章
- Organizer
  第50回原子爆弾後障害研究会
- Place of Presentation
  広島
- Year and Date
  2009-06-07
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] ヒストン脱メチル化酵素Fbxl10の7q-AML/MDS発症過程への関与2009
- Author(s)
  長町安希子, 松井啓隆, 安藝大輔, 尾崎佑子, 麻生博也, 宮崎和子, 山崎憲政, 小田秀明, 稲葉俊哉, 本田浩章
- Organizer
  第71回日本血液学会学術集会国立京都国際会館
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] bHLH型転写因子Declの発現調節はT細胞の胸腺内セレクションと分化に必要である2008
- Author(s)
  宮崎和子, 宮崎正輝, 山崎憲政, 菅野雅元, 本田浩章
- Organizer
  日本血液学会年会
- Place of Presentation
  京都
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-20591126
[Presentation] Haploinsufficiency and deficiency of a 7q gene Titan (Samd9L) predispose leukemia development in cooperation with deregulated expression of a transcription factor, Evi1, or a histone demethylase, Fbxl10.2008
- Author(s)
  Nagamachi A., Asou H., Matsui H., Ozaki Y., Aki D., Miyazaki K., Yamasaki N., Miyazaki M., Wolff L, Koller R., Oda H, Inaba T., Honda H.
- Organizer
  The 50^<th> Annual Meeting of American Society of Hematology
- Place of Presentation
  San Francisco, CA.
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] bHLH型転写因子Dec1の発現調節はT 細胞の胸腺内セレクションと分化に必要である2008
- Author(s)
  宮崎和子, 宮崎正輝, 山崎憲政, 菅野雅元, 本田浩章
- Organizer
  日本血液学会年会
- Place of Presentation
  京都
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-20591126
[Presentation] 7q欠失責任遺伝子候補Titanはアクチンリモデリングを制御する2008
- Author(s)
  松井啓隆, 長町安希子, 尾崎佑子, 安藝大輔, 麻生博也, 本田浩章, 稲葉俊哉
- Organizer
  第70回日本臨床血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] レトロウイルスを用いたTITANノックアウトマウスにおける白血病発症機構の解析2008
- Author(s)
  長町安希子, 麻生博也, 松井啓隆, 宮崎和子, 山崎憲政, 稲葉俊哉, 本田浩章
- Organizer
  第49回原子爆弾後障害研究会
- Place of Presentation
  長崎
- Year and Date
  2008-06-08
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] 7q-候補遺伝子TITANの欠失はTGFβ経路抑制やエピジェネティック変化と協調して白血病に関する2008
- Author(s)
  長町安希子, 麻生博也, 松井啓隆, 安藝大輔, 尾崎佑子, 宮崎和子, 山崎憲政, 小田秀明, 稲葉俊哉, 本田浩章
- Organizer
  第70回日本臨床血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] 白血病責任遺伝子MIKIによる細胞内小胞輸送の制御2008
- Author(s)
  安藝大輔, 竹村幸敏, 長町安希子, 本田浩章, 尾崎佑子, 松井啓隆, 麻生博也, 稲葉俊哉
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20390271
[Presentation] 胸腺内T細胞分化における転写因子DEC1の機能解析2007
- Author(s)
  宮崎正輝, 宮崎和子, 山崎憲政, 菅野雅元, 本田浩章
- Organizer
  第69回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Presentation] Analysis of molecular mechanism of CML blast crisis by retrovirus tagging2007
- Author(s)
  Yamasaki, N., Tazaki, T., Miyazaki, K., Oda, H., Komeno, Y., Kitaura, J., Warming, Soren, Jenkins, Nancy, Copeland, Neal, Honda, Z., Nakamura, T., Kitamura, T., Honda, H
- Organizer
  The 69th Annual Meeting of Japanese Society of Hematology
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Presentation] IRESによるAML1発現は胎生期における末梢血管形成および二次造血に必須である2007
- Author(s)
  本田浩章、馬峰、小田秀明、山崎憲政、奥田^3、辻浩一郎、宮崎和子
- Organizer
  第69回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Presentation] Functional analysis of transcriptional factor, DEC 1, in T cell differentiation in thymus2007
- Author(s)
  Miyazaki, M., Miyazaki, K., Oda, H., Kanno, M., Lemischka, I.R., Honda, H
- Organizer
  The 69th Annual Meeting of Japanese Society of Hematology
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Presentation] E2A/HLFは転写因子Gfil、 Ikaros、 Evi3と協調して白血病発症に関与する2007
- Author(s)
  田崎達也、宮崎和子、山崎憲政、小田秀明、稲葉俊哉、本田浩章
- Organizer
  第69回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Presentation] Analysis of the zinc finger domain protein Hemp-deficient mice2007
- Author(s)
  Miyazaki, K., Miyazaki, M., Tazaki, T., Yamasaki, N., Kanno, M., Oda, H., Lemischka, I.R., Honda. H
- Organizer
  The 69th Annual Meeting of Japanese Society of Hematology
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Presentation] Functional analysis of Src homology 3-encoding exon (exon 2) of p 130Cas in primary fibroblasts derived from exon 2-specific knockout mice2007
- Author(s)
  Tazaki, T., Miyazaki, K., Hiyama, E., Nakamoto, T., Sakai, R., Yamasaki, N., Honda, Z., Noda, M., Miyasaka, N., Sueda, T., Honda. H
- Organizer
  The 81th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Presentation] E2A/HLFは転写因子Gfi1、Ikaros、Evi3と協調して白血病発症に関与する2007
- Author(s)
  田崎達也、宮崎和子、山崎憲政、小田秀明、稲葉俊哉、本田浩章
- Organizer
  第69回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-18591064
[Presentation] MBT domainを有する新規蛋白Hempの胎児造血における機能解析2007
- Author(s)
  宮崎和子, 宮崎正輝, 田崎達也, 山崎憲政, 菅野雅元, 小田秀明, Ihor R. Lemischka, 本田浩章
- Organizer
  第69回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Presentation] SH3 (Src homology 3)をコードするexon 2を特異的にノックアウトしたマウス由来の線維芽細胞を用いたアダプター分子Casの機能解析2007
- Author(s)
  田崎達也、宮崎和子、檜山英三、中元哲也、堺隆一、山崎憲政、本田善一郎、野田政樹、宮坂信之、末田泰二郎、本田浩章
- Organizer
  第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-18591064
[Presentation] SH3(Src homology 3)をコードするexon 2を特異的にノックアウトしたマウス由来の線維芽細胞を用いたアダプター分子Casの機能解析2007
- Author(s)
  田崎達也、宮崎和子、檜山英三、中元哲也、堺隆一、山崎憲政、本田善一郎、野田政樹、宮坂信之、末田泰二郎、本田浩章
- Organizer
  第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Presentation] (^<*1>Dept Dev. Oncol.,^<*3> Dept. Stem Cell Biol.,^<*3> Div. Oncol. Inst. Med. Sci. Tokyo Univ.) Haploinsufficiency of Mild on 7q encoding a PARsylated protein induces mitotic disturbance characteristic to MDS/AML2007
- Author(s)
  Asou, H., Matsui, H., Honda,Ozaki,Y., Nagamachi, A., Aki, D., Yasunaga,S.^<*1>, Takihara, Y.^<*2>, Ohsugi, M.^<*3>, Inaba, T
- Organizer
  Proceedings 66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390284
[Presentation] (^<*1>Dept Dev. Oncol.) Kasumi/Titan, putative responsible genes for radiation induced leukemia, function in gene repair system induced by Mitomycin C2007
- Author(s)
  Asou, H., Nagamachi, A., Honda, H^<*1>., Ozald, Y., Matsui, H., Aki, D., Fujioka, K., Inaba, T
- Organizer
  The 48th Annual Meeting of Late Effects of Atomic Bomb
- Place of Presentation
  Hiroshima
- Year and Date
  2007-06-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390284
[Presentation] (^<*1>Dept. of Dev. Oncol. E2A/FLF cooperates with Gfil, Ikaros, or Evi3 transcription factor to induce leukemia2007
- Author(s)
  Tazaki, S.^<*1>, Miyazaki, K.^<*1>, Oda, H.^<*2>, Inaba, T., Honda, H.^<*1>
- Organizer
  The 69th Annual Meeting of Japanese Society of Hematology and The 49th Annual Meeting of Japanese Society of Clinical Hematology
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390284
[Presentation] Retrovirus taggingを用いた慢性骨髄性白血病急性転化機構の解析2007
- Author(s)
  山崎憲政、宮崎和子、小田秀明^1、米野由希子、北浦次郎、Sφren Warming、 Nancy A. Jenkins、 Neal G. Copeland、中村卓郎、北村俊雄、本田浩章
- Organizer
  第69回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Presentation] (^<*1>Dept. Dev. Oncol.) Miki, a putative responsible gene for radiation induced leukemia, plays an important role in cellular mitotic process. The 48th Annual Meeting of Late Effects of Atomic Bomb2007
- Author(s)
  Asou, H., Ozaki, Y., Matsui, R, Aid, D., Nagamachi, A., Honda, H^<*1>., Inaba, T
- Organizer
  The 48th Annual Meeting of Late Effects of Atomic Bomb
- Place of Presentation
  Hiroshima
- Year and Date
  2007-06-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390284
[Presentation] IRES-dependent AML expression is essential for blood vessel integrity and definitive hematopoiesis2007
- Author(s)
  Honda, H., Ma, F., Oda, H., Yamasaki, M., Okuda, T., Tsuji, K., Miyazaki, K
- Organizer
  The 69th Annual Meeting of Japanese Society of Hematology
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Presentation] (^<*1>Dept Dev. Oncol.) Candidate responsible genes isolated from 7q possibly involvement in ds-DNA break repair2007
- Author(s)
  Matsui, H., Asou, H., Honda, H.^<*1>", Nagamachi, A., Ozaki, Y, Aid, D., Fujioka, K., Inaba, T
- Organizer
  The 69th Annual Meeting of Japanese Society of Hematology and The 49th Annual Meeting of Japanese Society of Clinical Hematology
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390284
[Presentation] (^<*1>Dept. Dev. Oncol.) Involvement of novel myeloid tumor suppressor candidate genes on 7q in the DNA repair system2007
- Author(s)
  Matsui, H., Asou, H., Honda, H.^<*1>, Nagamachi, A., Ozaki, Y., Aki, D., Fujioka, K., Inaba, T
- Organizer
  Proceedings 66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390284
[Presentation] E2A/HLA cooperates with Gfi1, Ikaros, or Evi3 transcription factor to induce leukemia2007
- Author(s)
  Tazaki, T., Miyazaki, K., Oda, H., Inaba, T., Honda, H
- Organizer
  The 69th Annual Meeting of Japanese Society of Hematology
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591064
[Presentation] Identification of interacting partners for MAP kinase-interacting kinase 1
- Author(s)
  上田　健、福永理己郎、Roumiana Alexandrova、Theo Goh、Tak W. Mak、本田浩章
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590364

1. SAKAI Ryuichi (40215603)

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# of Collaborated Products: 1 results
80. 増井憲太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
81. 菊池次郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
82. 犬飼岳史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
83. 赤羽弘資

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
84. 渡辺秀人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
85. 須田年生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
86. 塩川大介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
87. 岡部幸司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Honda Hiroaki 本田 浩章

HONDA Hiroaki 本田 浩章

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Elucidation of molecular mechanisms underlying development of malignant tumors with loss-of-function mutations of UTX, a histone modifier, mainly focusing on urological tumors.Principal Investigator

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Elucidation of mechanisms underlying stem cell aging induced by deregulation of histone modifications and development of anti-aging therapies by maintaining their functionsPrincipal Investigator

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Functional analyses of enzymatic activity- and complex formation-dependent roles of UTX in the regulation of hematopoietic stem cells and development of hematopoietic diseasesPrincipal Investigator

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Analysis of pathogenic mechanisms of myelodysplastic syndrome by deregulation of histone H3K27Principal Investigator

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Honda Hiroaki 本田浩章

HONDA Hiroaki 本田浩章