Horie Kyoji 堀江恭二

… Alternative Names

HORIE Kyoji 堀江恭二

堀江恭二ホリエキョウジ

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Researcher Number	30333446
Other IDs
External Links
Affiliation (Current)	2022: 奈良県立医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2012 – 2022: 奈良県立医科大学, 医学部, 教授 2012: 大阪大学, 医学(系)研究科(研究院), 教授 2011: 大阪大学, 医学系・研究科, 准教授 2007 – 2011: Osaka University, 医学系研究科, 准教授 2008 – 2010: 大阪大学, 医学(系)研究科, 准教授 … More 2009: 大阪大学, 医学系研究科, 准教 2007: Osaka University, 医学糸研究科, 准教授 2005 – 2006: 大阪大学, 医学系研究科, 助教授 2003: 大阪大学, 先端化学技術共同研究センター, 助手 2002: 大阪大学, 先端科学技術共同研究センター, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Laboratory animal science / Laboratory animal science / Experimental pathology / Laboratory animal science / Applied genomics / Genome biology / 基礎ゲノム科学 / Integrative animal science / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Basic Section 42040:Laboratory animal science-related … More Except Principal Investigator … More Hematology / Laboratory animal science / Experimental pathology / Medium-sized Section 52:General internal medicine and related fields Less
Keywords	Principal Investigator 遺伝子 / ES細胞 / ゲノム / マウス / バイオテクノロジー / トランスポゾン / Bloom / 再生医学 / 変異体 / 発生・分化 … More / iPS細胞 / 遺伝学 / 発生工学 / ゲノム編集 / CRISPR / IAP / 幹細胞 / 多能性 / 全能性 / 癌 / 遺伝子変異 / 遺伝子トラップ / GFP / メチル化 / ポリAトラップ / 動物 / 変異マウス / レトロウイルス / バオテクノロジー / non-coding RNA / non-oding RNA / バーコード / ハプロイド / ベクター / レトロエレメント / エピジェネティクス / レトロトランスポゾン / 遺伝子発現 / retrotoransposon / mouse / genome / expression / 1細胞 / 蛍光 / 蛍光蛋白 / １細胞解析 / 蛍光タンパク / 1細胞解析 / 未分化状態 / 分化 … More Except Principal Investigator トランスポゾン / トランスポゾンシステム / ミュタゲネーシス / C57BL / 6マウス / 表現型解析 / 病態モデル / C57BL/6マウス / 慢性骨髄性白血病 / がん抑制遺伝子 / 再生医学 / テラトーマ / 再生医療 / lincRNA / 細胞分化 / 血球分化 / ES細胞 / スクリーニング / ノックアウトマウス / 新規遺伝子 / 血友病A / 細胞治療 / 細胞シート / iPS細胞 / 間葉系幹細胞 / 第VIII因子 / 肝類洞内皮細胞 / マウス Less

全能性状態の誘導による人工的動物個体作製法の開発Principal Investigator
- Principal Investigator
  
  堀江恭二
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Nara Medical University
Development of Universal Cell Therapy for Hemophilia A 
- Principal Investigator
  
  嶋緑倫
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nara Medical University
Time-series measurement of totipotent state and establishment of totipotent stem cells using a novel long-term single-cell tracking methodPrincipal Investigator
- Principal Investigator
  
  Horie Kyoji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Nara Medical University
Study of the gene regulatory network of ES cells by long-term single cell analysis using a microfluidic devicePrincipal Investigator
- Principal Investigator
  
  Horie Kyoji
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Integrative animal science
- Research Institution
  Nara Medical University
Elucidation of super-undifferentiated state of mouse ES cells and application to reprogramming of ES/iPS cells of other speciesPrincipal Investigator
- Principal Investigator
  
  Horie Kyoji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Nara Medical University
発現のオンとオフを繰り返す少数分子によるES細胞の多能性の制御Principal Investigator
- Principal Investigator
  
  堀江恭二
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Medical University
Screening for regulatory factors of iPS cell generation using haploid ES cellsPrincipal Investigator
- Principal Investigator
  
  Horie Kyoji
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Nara Medical University
Elucidation of the mechanism of maintenance of ES cell pluripotency through analyses of regulatory factors of retroelementsPrincipal Investigator
- Principal Investigator
  
  HORIE Kyoji
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Nara Medical University
Genome-wide screening for the genes essential for the maintenance of mouse embryonic stem cellsPrincipal Investigator
- Principal Investigator
  
  HORIE Kyoji
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Nara Medical University
  Osaka University
Isolation and analysis of mutants that do not form teratoma using homo-mutagenized mouse ES cell library
- Principal Investigator
  
  YOSHIMURA Yasuhide
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Osaka University
Screening of a novel factor that regulates hematopoiesis using a homozygous mutant ES cell library
- Principal Investigator
  
  TOKUNAGA MASAHIRO
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
Comprehensive analysis of mutant mammalian cells using barcode vectorPrincipal Investigator
- Principal Investigator
  
  HORIE Kyoji
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Osaka University
Functional analysis of mouse noncoding RNAs by a rapid gene disruption methodPrincipal Investigator
- Principal Investigator
  
  HORIE Kyoji
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genome biology
- Research Institution
  Nara Medical University
  Osaka University
トランスポゾンを用いた網羅的変異マウス作製によるゲノム機能の解析Principal Investigator
- Principal Investigator
  
  堀江恭二
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Isolation of novel anti-oncogenes using transposon in model mice for chronic myelogenous leukemia
- Principal Investigator
  
  HONDA Hiroaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Hiroshima University
Mutagenesis using transposon system in C57BL/6 mice
- Principal Investigator
  
  TAKEDA Junji
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Osaka University
Construction of a homozygous mutant embryonic stem cell bankPrincipal Investigator
- Principal Investigator
  
  HORIE Kyoji
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Osaka University
遺伝子機能解析を迅速化するための新しい両アレル変異導入法の開発Principal Investigator
- Principal Investigator
  
  堀江恭二
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied genomics
- Research Institution
  Osaka University
トランスポゾンを用いた網羅的変異マウス作製によるゲノム機能の解析Principal Investigator
- Principal Investigator
  
  堀江恭二
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
トランスポゾンを用いた網羅的変異マウス作製によるゲノム機能の解析Principal Investigator
- Principal Investigator
  
  堀江恭二
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Generation of Model Mice for the Study of Retrotransposons in Living OrganismsPrincipal Investigator
- Principal Investigator
  
  HORIE Kyoji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  基礎ゲノム科学
- Research Institution
  Osaka University
マウストランスポゾンシステムを用いた体細胞遺伝子変異導人と発癌モデルマウスの樹立Principal Investigator
- Principal Investigator
  
  堀江恭二
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Osaka University
マウストランスポゾンによる生殖系列での遺伝子変異導入と変異マウスの作製Principal Investigator
- Principal Investigator
  
  堀江恭二
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Osaka University

All 2022 2021 2019 2018 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Patent

[Journal Article] Removal of reprogramming transgenes improves the tissue reconstitution potential of keratinocytes generated from human induced pluripotent stem cells.2014
- Author(s)
  Ken Igawaa, Chikara Kokubu, Kosuke Yusa, Kyoji Horie, Yasuhide Yoshimura, Kaori Yamauchi, Hirofumi Suemori, Hiroo Yokozeki, Masashi Toyoda, Nobutaka Kiyokawa, Hajime Okita, Yoshitaka Miyagawa, Hidenori Akutsu, Akihiro Umezawa, Ichiro Katayama, Junji Takeda.
- Journal Title
  
  STEM CELLS Transl Med
  
  Volume: 3 Pages: 992-1001
- DOI
  10.5966/sctm.2013-0179
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-22310118, KAKENHI-PROJECT-24591651, KAKENHI-PROJECT-24615003, KAKENHI-PROJECT-25461665, KAKENHI-PROJECT-25640048, KAKENHI-PROJECT-24241064
[Journal Article] Simulation and estimation of gene number in a biological pathway using almost complete saturation mutagenesis screening of haploid mouse cells.2014
- Author(s)
  Tokunaga M, Kokubu C, Maeda Y, Sese J, Horie K, Sugimoto N, Kinoshita T, Yusa K, Takeda J.
- Journal Title
  
  BMC Genomics
  
  Volume: 15 Pages: 1016-1016
- DOI
  10.1186/1471-2164-15-1016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22310118, KAKENHI-PROJECT-26640062, KAKENHI-PROJECT-26640124, KAKENHI-PROJECT-26860731
[Journal Article] An in vitro ES cell-based clock recapitulation assay model identifies CK2a as an endogenous clock regulator.2013
- Author(s)
  Umemura Y, Yoshida J, Wada M, Tsuchiya Y, Minami Y, Watanabe H, Kondoh G, Takeda J, Inokawa H, Horie K, Yagita K.
- Journal Title
  
  PLoS ONE
  
  Volume: 8
- DOI
  10.1371/journal.pone.0067241
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22310118, KAKENHI-PROJECT-23390051, KAKENHI-PROJECT-24659109, KAKENHI-PROJECT-25250012
[Journal Article] SMOC1 is essential for ocular and limb development in humans and mice.2011
- Author(s)
  Okada I, Hamanoue H, Terada K, Tohma T, Megarbane A, Chouery E, Abou-Ghoch J, Jalkh N, Cogulu O, Ozkinay F, Horie K, Takeda J, Furuichi T, Ikegawa S, Nishiyama K, Miyatake S, Nishimura A, Mizuguchi T, Niikawa N, Hirahara F, Kaname T, Yoshiura K, Tsurusaki Y, Doi H, Miyake N, Furukawa T, Matsumoto N, Saitsu H.
- Journal Title
  
  Am J Hum Genet. 88
  
  Pages: 30-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200034
[Journal Article] A homozygous mutant embryonic stem cell bank applicable for phenotype-driven genetic screening2011
- Author(s)
  Horie K.
- Journal Title
  
  Nat Methods
  
  Volume: 8 Pages: 1071-1077
- DOI
  10.1038/nmeth.1739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500388, KAKENHI-PUBLICLY-22116509, KAKENHI-PROJECT-22310118, KAKENHI-PROJECT-22700454, KAKENHI-PUBLICLY-23116704
[Journal Article] Development of the circadian oscillator during differentiation of mouse embryonic stem cells in vitro.2010
- Author(s)
  Yagita K, Horie K, Koinuma S, Nakamura W, Yamanaka I, Urasaki A, Shigeyoshi Y, Kawakami K, Shimada S, Takeda J, Uchiyama Y.
- Journal Title
  
  Proc Natl Acad Sci USA. 107(8)
  
  Pages: 3846-3851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200034
[Journal Article] Functional genomics in the mouse using the sleeping beauty transposon system.2010
- Author(s)
  Horie K, Kokubu C, Takeda J.
- Journal Title
  
  Methods Enzymol. 477
  
  Pages: 71-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200034
[Journal Article] Essential role of neuron-enriched diacylglycerol kinase (DGK), DGKbeta in neurite spine formation, contributing to cognitive function.2010
- Author(s)
  Shirai Y, Kouzuki T, Kakefuda K, Moriguchi S, Oyagi A, Horie K, Morita SY, Shimazawa M, Fukunaga K, Takeda J, Saito N, Hara H.
- Journal Title
  
  PLoS One. 5(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200034
[Journal Article] Diacylglycerol kinase β knockout mice exhibit lithium-sensitive behavioral abnormalities.2010
- Author(s)
  Kakefuda K, Oyagi A, Ishisaka M, Tsuruma K, Shimazawa M, Yokota K, Shirai Y, Horie K, Saito N, Takeda J, Hara H.
- Journal Title
  
  PLoS One. 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200034
[Journal Article] Generating mutant rats using the Sleeping Beauty transposon system.2009
- Author(s)
  Kitada K, Keng VW, Takeda J, Horie K.
- Journal Title
  
  Methods. 49(3)
  
  Pages: 236-242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200034
[Journal Article] A transposon-based chromosomal engineering method to survey a large cis-regulatory landscape in the mouse genome.2009
- Author(s)
  Kokubu C, Horie K, Abe K, Ikeda R, Mizuno S, Uno Y, Ogiwara S, Ohtsuka M, Isotani A, Okabe M, Imai K, Takeda J
- Journal Title
  
  Nature Genet. 41
  
  Pages: 946-952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200034
[Journal Article] Translation from nonautonomous type IAP retrotransposon is a critical determinant of transposition activity : implication for retrotransposon-mediated genome evolution.2008
- Author(s)
  Saito ES, Keng VW, Takeda J, Horie K
- Journal Title
  
  Genome Res. 18(6)
  
  Pages: 859-868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200034
[Journal Article] Retrotransposons Influence the Mouse Transcriptome: Implication for the Divergence of Genetic Traits2007
- Author(s)
  Horie K.
- Journal Title
  
  Genetics 176
  
  Pages: 815-827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200034
[Journal Article] Retrotransposons influence the mouse transcriptome: implication for the divergence of genetic traits.2007
- Author(s)
  Horie, K, et. al.
- Journal Title
  
  Genetics 176
  
  Pages: 815-827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18016014
[Journal Article] Germline mutagenesis mediated by Sleeping Beauty transposon system in mice.2007
- Author(s)
  Takeda VW.Keng, K Horie
- Journal Title
  
  Genome Biol. 8(Suppl 1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200034
[Journal Article] Retrotransposons influence the mouse transcriptome : implication for the divergence of genetic traits
- Author(s)
  Horie K, et al.
- Journal Title
  
  Genetics (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510158
[Journal Article] Retrotransposons influence the mouse transcriptome : implication for the divergence of genetic traits
- Author(s)
  Horie K.
- Journal Title
  
  Genetics (In Press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510158
[Patent] 異常行動を示す遺伝子改変非ヒト哺乳動物及びその作製方法2008
- Inventor(s)
  竹田潤二、堀江恭二、八戸宏二郎、山田清文、田熊一敞
- Industrial Property Rights Holder
  財団法人大阪産業振興機構、国立大学法人大阪大学、国立大学法人金沢大学
- Filing Date
  2008-07-28
- Data Source
  KAKENHI-PROJECT-19200034
[Presentation] N-myristoyltransferaseの阻害によるマウス及びヒト多能性幹細胞のナイーブ性の亢進2022
- Author(s)
  堀江恭二
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-20H03174
[Presentation] N-myristoyltransferaseの阻害によるマウス及びヒト多能性幹細胞のナイーブ性の亢進2021
- Author(s)
  吉田純子, 渡邊仁美, 山内香織, 西久保拓真, 磯谷綾子, 大塚哲, 丹羽仁史, 阿久津英憲, 梅澤明弘, 末盛博文, 高島康弘, 近藤玄, 竹田潤二, 堀江恭二
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03174
[Presentation] Identifying the heterogeneity of ground state pluripotency in mouse embryonic stem cells and elucidating its regulatory mechanism2019
- Author(s)
  Kyoji Horie, Hitomi Watanabe, Yosuke Nishimura, Hikaru Watanabe, Masahide Seki, Akio Seita, Kagayaki Kato, Yuichi Wakayama, Jun Sese, Yutaka Suzuki, Takuji Yamada, Gen Kondoh, Junko Yoshida
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04683
[Presentation] Identifying the heterogeneity of ground state pluripotency in mouse embryonic stem cells and elucidating its regulatory mechanism2019
- Author(s)
  Kyoji Horie, Hitomi Watanabe, Yosuke Nishimura, Hikaru Watanabe, Masahide Seki, Akio Seita, Kagayaki Kato, Yuichi Wakayama, Jun Sese, Yutaka Suzuki, Takuji Yamada, Gen Kondoh, Junko Yoshida
- Organizer
  第42回日本分子生物学会年会　2019.12.4 福岡
- Invited
- Data Source
  KAKENHI-PROJECT-18K19275
[Presentation] Identifying heterogeneity of ground state pluripotency in mouse embryonic stem cells2018
- Author(s)
  Kyoji Horie, Junko Yoshida
- Organizer
  International Society for Stem Cell Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19275
[Presentation] Identifying heterogeneity of ground state pluripotency in mouse embryonic stem cells2018
- Author(s)
  Kyoji Horie, Junko Yoshida
- Organizer
  International Society for Stem Cell Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04683
[Presentation] Ground stateにおけるマウスES細胞の不均一性の同定2018
- Author(s)
  堀江恭二, 渡邊仁美, 西村陽介, 渡邊日佳流, 関真秀, 清田晃央, 加藤輝, 若本祐一, 鈴木穣, 山田拓司, 近藤玄, 吉田純子
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H04683
[Presentation] Ground stateにおけるマウスES細胞の不均一性の同定2018
- Author(s)
  堀江恭二, 渡邊仁美, 西村陽介, 渡邊日佳流, 関真秀, 清田晃央, 加藤輝, 若本祐一, 鈴木穣, 山田拓司, 近藤玄, 吉田純子
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19275
[Presentation] Genome-wide comparative analyses of retroviral and DNA-type transposon vector integration sties2015
- Author(s)
  Junko Yoshida, Keiko Akagi, Chikara Kokubu, Junji Takeda, Kyoji Horie
- Organizer
  Conference on Transposition and Genome Engineering 2015
- Place of Presentation
  Nara, Japan
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640062
[Presentation] Genome-wide comparative analyses of retroviral and DNA-type transposon vector integration sties2015
- Author(s)
  Junko Yoshida, Keiko Akagi, Chikara Kokubu, Junji Takeda, Kyoji Horie
- Organizer
  Conference of Transposon and Genome Engineering 2015
- Place of Presentation
  Nara, Japan
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26115712
[Presentation] レトロウイルスおよびトランスポゾンベクターのゲノムワイドな挿入部位解析2013
- Author(s)
  吉田純子、竹田潤二、堀江恭二
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24650236
[Presentation] Genome-wide comparative analyses of retroviral and DNA-type transposon vector integration sites in mouse embryonic stem cells : Implication for reprogramming study2013
- Author(s)
  Yoshida J, Horie K.
- Organizer
  11th Annual Meeting of International Society for Stem Cell Research
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-25640048
[Presentation] Genome-wide comparative analyses of retroviral and DNA-type transposon vector integration sites in mouse embryonic stem cells : Implication for reprogramming study2013
- Author(s)
  Yoshida J, Horie K.
- Organizer
  11th Annual Meeting of International Society for Stem Cell Research
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-22310118
[Presentation] Genome-wide comparative analyses of retroviral and DNA-type transposon vector integration sites in mouse embryonic stem cells : Implication for reprogramming study.2013
- Author(s)
  Yoshida J, Horie K.
- Organizer
  11th Annual Meeting of International Society for Stem Cell Research
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24650236
[Presentation] レトロウィルスおよびトランスポゾンベクターのゲノムワイドな挿入部位解析2013
- Author(s)
  吉田純子、竹田潤二、堀江恭二
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22310118
[Presentation] レトロウィルスおよびトランスポゾンベクターのゲノムワイドな挿入部位解析2013
- Author(s)
  吉田純子、竹田潤二、堀江恭二
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24650236
[Presentation] Genome-wide comparative analyses of retroviral and DNA-type transposon vector integration sites in mouse embryonic stem cells : Implication for reprogramming study2013
- Author(s)
  Junko Yoshida, Kyoji Horie
- Organizer
  11^<th> Annual Meeting of International Society for Stem Cell Research
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24650236
[Presentation] Screening for critical epigenetic factors involved with the regulation of pluripotency and differentiation using a homozygous mutant mouse embryonic stem cell bank2012
- Author(s)
  Yoshida J, Takeda J, Horie K
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-22310118
[Presentation] ホモ変異体ES細胞バンクを用いたマウスES細胞の多能性制御因子の遺伝学的スクリーニングとエピゲノム解析2012
- Author(s)
  吉田純子、竹田潤二、堀江恭二
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22310118
[Presentation] 両アレル変異導入法を用いたES細胞の未分化性制御機構の解析2011
- Author(s)
  堀江恭二、國府力、吉田純子、竹田潤二
- Place of Presentation
  東京
- Year and Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-19300146
[Presentation] 両アレル変異導入法を用いたES細胞の未分化性制御機構の解析2011
- Author(s)
  堀江恭二
- Organizer
  日本再生医療学会総会
- Place of Presentation
  東京
- Year and Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-19300146
[Presentation] A homozygous mutant mouse embryonic stem cell bank readily applicable for phenotype driven genetic screening2010
- Author(s)
  堀江恭二
- Organizer
  International Society for Stem Cell Research (ISSCR) 8^<th> Annual Meeting
- Place of Presentation
  San Francisco, USA.
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-19300146
[Presentation] A homozygous mutant mouse embryonic stem cell bank readily applicable for phenotype-driven genetic screening.2010
- Author(s)
  堀江恭二, 國府力, 吉田純子, 竹田潤二
- Organizer
  Instenational Society for Stem Cell Research (ISSCR) 8th Annual Meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-19300146
[Presentation] レトロウィルスおよびDNA型トランスポゾンベクターのゲノムワイドな挿入部位の比較解析2010
- Author(s)
  吉田純子、國府力、竹田潤二、堀江恭二
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-19200034
[Presentation] 迅速な遺伝子機能解析を可能にするホモ変異体ES細胞バンクの作製2009
- Author(s)
  堀江恭二
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-20016015
[Presentation] To12 transposonを用いたマウスES細胞ゲノムへの変異導入2009
- Author(s)
  吉田純子、國府力、川上浩一、竹田潤二、堀江恭二
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-19200034
[Presentation] Rapid identification of homozygous mutant mouse embryonic stem cell clones showing differentiation resistant or differentiation prone phenotype
- Author(s)
  Junko Yoshida, Kyoji Horie
- Organizer
  Global Controls in Stem Cells
- Place of Presentation
  Biopolis, Syngapore
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-26640062
[Presentation] Live cell imaging for the analysis of cellular heterogeneity in mouse embryonic stem cell mutant clones identified by forward genetic screening
- Author(s)
  Junko Yoshida, Kyoji Horie
- Organizer
  12th Annual Meeting of International Society for Stem Cell Research
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-22310118
[Presentation] Live cell imaging for the analysis of cellular heterogeneity in mouse embryonic stem cell mutant clones identified by forward genetic screening
- Author(s)
  Junko Yoshida, Kyoji Horie
- Organizer
  12th Annual Meeting of International Society for Stem Cell Research
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PUBLICLY-26115712
[Presentation] ホモ変異体マウスES細胞バンクを用いた包括的遺伝子機能解析
- Author(s)
  堀江恭二、吉田純子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-26115712
[Presentation] ホモ変異体マウスES細胞バンクを用いた迅速な表現型スクリーニング
- Author(s)
  堀江恭二
- Organizer
  理研シンポジウム
- Place of Presentation
  つくば
- Invited
- Data Source
  KAKENHI-PROJECT-22310118
[Presentation] Live cell imaging for the analysis of cellular heterogeneity in mouse embryonic stem cell mutant clones identified by forward genetic screening
- Author(s)
  Junko Yoshida, Kyoji Horie
- Organizer
  12th Annual Meeting of International Society for Stem Cell Research
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-25640048
[Presentation] ホモ変異体マウスES細胞バンクを用いた包括的遺伝子機能解析
- Author(s)
  堀江恭二、吉田純子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-26640062
[Presentation] Live cell imaging for the analysis of cellular heterogeneity in mouse embryonic stem cell mutant clones identified by forward genetic screening
- Author(s)
  Junko Yoshida, Kyoji Horie
- Organizer
  12th Annual Meeting of International Society for Stem Cell Research
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-26640062
[Presentation] ホモ変異体マウスES細胞バンクを用いた包括的遺伝子機能解析
- Author(s)
  堀江恭二、吉田純子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-25640048
[Presentation] ホモ変異体マウスES細胞バンクを用いた包括的遺伝子機能解析
- Author(s)
  堀江恭二、吉田純子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-22310118
[Presentation] Rapid identification of homozygous mutant mouse embryonic stem cell clones showing differentiation resistant or differentiation prone phenotype
- Author(s)
  Junko Yoshida, Kyoji Horie
- Organizer
  Global Controls in Stem Cells
- Place of Presentation
  Biopolis, Syngapore
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PUBLICLY-26115712
[Presentation] Rapid identification of homozygous mutant mouse embryonic stem cell clones showing differentiation resistant or differentiation prone phenotype
- Author(s)
  Junko Yoshida, Kyoji Horie
- Organizer
  Global Controls in Stem Cells
- Place of Presentation
  Biopolis, Syngapore
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-22310118
[Presentation] Rapid identification of homozygous mutant mouse embryonic stem cell clones showing differentiation resistant or differentiation prone phenotype
- Author(s)
  Junko Yoshida, Kyoji Horie
- Organizer
  Global Controls in Stem Cells
- Place of Presentation
  Biopolis, Syngapore
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-25640048

1. TAKEDA Junji (50163407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. HONDA Hiroaki (40245064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HONDA ZenーIchiro (70238814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. YOSHIMURA Yasuhide (60263307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TOKUNAGA MASAHIRO (90597410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. WAKAMOTO Yuichi (30517884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YOSHIDA Junko (30769196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 嶋緑倫 (30162663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 辰巳公平 (70555432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 坂田飛鳥 (90528457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 小田朗永 (80547703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 荻原建一 (50623500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMANISHI Ayako

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YOKOZEKI Hiroo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. ISOTANI Ayako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 八木田和弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 井之川仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 近藤科江

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 近藤玄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 井川健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 山内香織

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Horie Kyoji 堀江 恭二

HORIE Kyoji 堀江 恭二

堀江 恭二 ホリエ キョウジ

Research Projects

Research Products

Co-Researchers

全能性状態の誘導による人工的動物個体作製法の開発Principal Investigator

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Development of Universal Cell Therapy for Hemophilia A&#160;

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Time-series measurement of totipotent state and establishment of totipotent stem cells using a novel long-term single-cell tracking methodPrincipal Investigator

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Study of the gene regulatory network of ES cells by long-term single cell analysis using a microfluidic devicePrincipal Investigator

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Elucidation of super-undifferentiated state of mouse ES cells and application to reprogramming of ES/iPS cells of other speciesPrincipal Investigator

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発現のオンとオフを繰り返す少数分子によるES細胞の多能性の制御Principal Investigator

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Screening for regulatory factors of iPS cell generation using haploid ES cellsPrincipal Investigator

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Elucidation of the mechanism of maintenance of ES cell pluripotency through analyses of regulatory factors of retroelementsPrincipal Investigator

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Genome-wide screening for the genes essential for the maintenance of mouse embryonic stem cellsPrincipal Investigator

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Isolation and analysis of mutants that do not form teratoma using homo-mutagenized mouse ES cell library

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Screening of a novel factor that regulates hematopoiesis using a homozygous mutant ES cell library

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Comprehensive analysis of mutant mammalian cells using barcode vectorPrincipal Investigator

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Functional analysis of mouse noncoding RNAs by a rapid gene disruption methodPrincipal Investigator

Principal Investigator

Horie Kyoji 堀江恭二

HORIE Kyoji 堀江恭二

堀江恭二ホリエキョウジ

Development of Universal Cell Therapy for Hemophilia A