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Hashimoto Shinichi  橋本 真一

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… Alternative Names

HASHIMOTO Shinichi  橋本 真一

HASHIMOTO Shin-ichi  橋本 慎一

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Researcher Number 00313099
Other IDs
Affiliation (Current) 2025: 和歌山県立医科大学, 先端医学研究所, 教授
Affiliation (based on the past Project Information) *help 2019 – 2024: 和歌山県立医科大学, 先端医学研究所, 教授
2019: 和歌山県立医科大学, 和歌山県立医科大学 先端医学研究所, 教授
2016 – 2019: 金沢大学, 医薬保健学総合研究科, 特任教授
2011 – 2015: 金沢大学, 医学系, 特任教授
2011: 金沢大学, 医学系研究科, 特任教授 … More
2011: 金沢大学, 医薬保健研究域, 特任教授
2011: 金沢大学, 医薬保健研究域医学系, 特任教授
2009 – 2010: 東京大学, 大学院・新領域創成科学研究科, 特任准教授
2009: The University of Tokyo, 新領域創成科学研究科, 特任准教授
2007 – 2008: 東京大学, 大学院・医学系研究科, 助教
2006: 東京大学, 大学院医学系研究科, 助手
2000 – 2006: 東京大学, 大学院・医学系研究科, 助手
2004: The University of Tokyo, Graduate School of Medicine, Research Associate, 大学院医学系研究科, 助手
2000 – 2001: 東京大学, 医学系研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Basic Section 50020:Tumor diagnostics and therapeutics-related / 基礎ゲノム科学 / Medical genome science
Except Principal Investigator
Immunology / Basic Section 59040:Nutrition science and health science-related / Basic Section 48040:Medical biochemistry-related / Human pathology / Complex systems / Biological Sciences … More / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56060:Ophthalmology-related / Basic Section 53010:Gastroenterology-related / Basic Section 54010:Hematology and medical oncology-related / Gastroenterology / 内科学一般 / Genome biology Less
Keywords
Principal Investigator
遺伝子発現 / SAGE / シングルセル / 樹状細胞 / 組織空間情報 / 5'SAGE / ゲノム / single cell / 癌 / エピジェネティクス … More / 転写開始点 / 免疫 / 血液細胞 / マルチオミックス / ゲノム変異 / 組織 / 時空間解析 / 組織微小環境 / Single Cell / Cancer microenvironment / Spatial transcriptome / Single-cell / Genome mutation / cancer / microenvironment / spatial transcriptome / transcriptional start site / immunology / blood / leukocytes / Gene expression / CDS T cell / MK cell / DNAチップ / プロモータ / 白血球 / バイオテクノロジー / gene expression / モニタリング / 1細胞 / がん幹細胞 / 癌細胞 / 1細胞 / 次世代超高速DNAシーケンサー / 次世DNAシーケンサー / トランスクリプトーム / 次世代DNAシーケンサー / 脱アセチル化阻害剤 / DNAメチル化 / HIV / 抗原提示細胞 / Th2 / Th1 … More
Except Principal Investigator
遺伝子 / 病理学 / 老化 / 免疫学 / 膵癌 / 老化細胞 / モデル化 / 情報工学 / 肺線維症 / Th2 / Th1 / DNA array / 感染症 / トランスクリプトーム解析 / 免疫記憶 / ケモカイン / 発現制御 / ゲノム / 免疫チェックポイント阻害薬 / トラジェクトリー / 軌跡地図 / 間質 / がん免疫治療 / 老化制御 / 1細胞解析 / Senolytic薬 / B細胞 / リンパ増殖性疾患 / 自己免疫疾患 / 免疫細胞 / 再生 / 肺気腫 / COPD / セノリシス / 細胞老化 / レチノイン酸代謝酵素 / 角膜創傷治癒 / マウス / 神経麻痺性角膜症 / 遺伝子解析 / EUS-FNA / 超音波内視鏡下穿刺吸引生検 / 包括的1細胞遺伝子解析 / 病理診断 / 遺伝子発現 / 人工知能 / 穿刺生検 / 膵腫瘍 / 超音波内視鏡 / thymosin-β4 / がん微小環境 / 遺伝子改変マウス / thymosin / がん免疫 / 間質細胞 / シングルセル遺伝子発現解析 / 老化関連遺伝子 / TCR transfectant / T cell receptor / HLAクラスI欠失血球 / T細胞レセプタートランスフェクタント / シクロスポリン / 末梢血造血幹前駆細胞 / TCRトランスフェクタント / T cell receptor (TCR) / モノクローナル抗体 / 細胞傷害性T細胞 / HLA / HLA-DR15 / 発作性夜間ヘモグロビン尿症 / T細胞レセプター / HLA-B*40:02 / 自己抗原 / 再生不良性貧血 / 細胞・組織 / 分子生物学 / 腫瘍学 / Tumor antigen / 免疫病理診断 / 腫瘍免疫 / Immunohistochemistry / Immune response / Tumor immune escape / Single cell analysis / Cancer stem cell / Tumor microenvironment / 免疫病理バイオマーカー / 単細胞遺伝子発現解析 / がん免疫応答 / がん組織微小環境 / 腫瘍組織微小環境 / 免疫チェックポイント阻害剤 / がん抗原 / シングルセル遺伝子解析 / がん幹細胞 / 単細胞遺伝子解析 / がん最適化治療 / バイオマーカー / 免疫組織染色 / がん免疫療法 / T細胞抗原受容体 / 腫瘍微小環境 / 1細胞遺伝子解析 / 肝疾患 / 1細胞遺伝子解析 / 原発性胆汁性胆管炎 / 病理 / シングルセルトランスクリプトーム / 細胞間相互作用 / RNA-seq / single-cell / ネットワーク解析 / single-cell RNA-seq / 免疫 / ウィルス / ウイルス / 脂質代謝 / 線維症 / トランスクリプトーム / 線維芽細胞 / 転写因子 / Africa / HIV infection / 免疫病態 / HIV感染者 / アフリカ / HIV感染 / 免疫制御・移植免疫 / 造血幹細胞 / 自己免疫 / 免疫不全 / 免疫制御 / T細胞 / GVHD / 造血幹細胞移植 / 移植免疫 / メダカゲノム / ヒトゲノム / 近交系 / 進化 / 塩基置換 / DNAメチル化 / メモリーCTL / リンパ節 / CCR7 / regulatory T cells / 遊走 / DOCK2 / リンパ球 / シグナル伝達 / 樹状細胞 / シグナル / 細胞動態 / 免疫寛容 / 維持 / 好中球 / 場 / 次世代DNAシークエンサー / 免疫記憶の維持 / 誘導 / マクロファージ / Myeloid derived suppressor cells / 次世代DNA シークエンサー / 免疫応答の場 / CTL / 生体分子 / 蛋白質 / バイオテクノロジー Less
  • Research Projects

    (31 results)
  • Research Products

    (117 results)
  • Co-Researchers

    (73 People)
  •  光遊離バーコードビーズを用いた組織微小環境の統合解析法の確立Principal Investigator

    • Principal Investigator
      橋本 真一
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Wakayama Medical University
  •  組織再生と加齢に伴う呼吸器機能変化の関連解析と治療戦略の展開

    • Principal Investigator
      杉本 昌隆
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  thymosin-β4シグナルの破綻によるリンパ球分化・増殖異常の機構解明

    • Principal Investigator
      森田 強
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Wakayama Medical University
  •  がん免疫治療下における間質軌跡地図の空間解析と新しい間質リプログラミング法の確立

    • Principal Investigator
      田中 伸之
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Keio University
  •  レチノイン酸シグナルに焦点を当てた神経麻痺性角膜症に対する新規治療戦略の樹立

    • Principal Investigator
      岡田 由香
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Wakayama Medical University
  •  老化細胞の特定と老化細胞死誘導剤Senolytic薬による老化制御の達成

    • Principal Investigator
      石神 昭人
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Spatial transcriptome analysis using photoreleasing barcodesPrincipal Investigator

    • Principal Investigator
      Shinichi Hashimoto
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Wakayama Medical University
  •  Functional analysis of thymosin-beta 4 in the tumor microenvironment and its applications

    • Principal Investigator
      Tsuyoshi Morita
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Wakayama Medical University
  •  Development of next generation diagnostic technologies using biopsy tissues of pancreatic carcinoma: pathological diagnosis with artificial intelligence and single cell gene expression analysis

    • Principal Investigator
      Kitano Masayuki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Wakayama Medical University
  •  Identification of autoantigens presented by specific HLA class I alleles in aplastic anemia

    • Principal Investigator
      NAKAO Shinji
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Kanazawa University
  •  Identification of senescent cells in the tissues of aged animals and the effect of their removal on prolonging individual life span.

    • Principal Investigator
      Ishigami Akihito
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Preventive medicine through inflammation cellular sociology

    • Principal Investigator
      Matsushima Kouji
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Tokyo University of Science
      The University of Tokyo
  •  Inflammation cellular society in pulmonary fibrosis

    • Principal Investigator
      Matsushima Kouji
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Tokyo University of Science
      The University of Tokyo
  •  Single cell analysis of autoimmune liver diseases

    • Principal Investigator
      Harada Kenichi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      Kanazawa University
  •  Basic research on the immunohistological categorization of tumor microenvironment

    • Principal Investigator
      TORIGOE Toshihiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Human pathology
    • Research Institution
      Sapporo Medical University
  •  Mechanisms of transcriptional regulation of fibroblast activation in pulmonary fibrosis

    • Principal Investigator
      Matsushima Kouji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Tokyo University of Science
      The University of Tokyo
  •  Elucidation of the mechanisms of HBV infection using single cell transcriptome analysis

    • Principal Investigator
      HONDA Masao
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Kanazawa University
  •  Classification of the cell hierarchy structure by single cell transcriptomePrincipal Investigator

    • Principal Investigator
      Hashimoto Shinichi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical genome science
    • Research Institution
      Kanazawa University
  •  Cellular and molecular bases for chronic GVHD

    • Principal Investigator
      Matsushima Kouji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  Genome evolution induced by chromatin structure and DNA methylation

    • Principal Investigator
      MORISHITA Shinichi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Genome biology
    • Research Institution
      The University of Tokyo
  •  Elucidation of the molecular bases of the generation and maintenance of CTL memory by next generation DNA sequencer

    • Principal Investigator
      MATSUSHIMA Kouji
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  5'-end transcriptome and DNA methylation in cells treated with histone deacetylase inhibitor.Principal Investigator

    • Principal Investigator
      HASHIMOTO Shinichi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      基礎ゲノム科学
    • Research Institution
      Kanazawa University
      The University of Tokyo
  •  Cellular dynamics in autoimmune responses

    • Principal Investigator
      MATSUSHIMA Kouji
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Analysis of generation and control mechanism of CD8+ T cells by chemokines

    • Principal Investigator
      MATSUSHIMA Kouji
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  Transcriptome analysis using full-length enriched cDNA library and technology develop ment

    • Principal Investigator
      SUGANO Sumio
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  5'-endSAGE法を用いた包括的エピジェネティクスPrincipal Investigator

    • Principal Investigator
      橋本 真一
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      基礎ゲノム科学
    • Research Institution
      The University of Tokyo
  •  SAGE法によるヒト血液細胞の遺伝子発現解析Principal Investigator

    • Principal Investigator
      橋本 真一
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  HIV感染免疫担当細胞の包括的遺伝子発現解析Principal Investigator

    • Principal Investigator
      橋本 真一
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  SAGE法によるヒト血液細胞の遺伝子発現解析Principal Investigator

    • Principal Investigator
      橋本 真一
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  A study of immune status of HIV-infected persons

    • Principal Investigator
      OISHI Kazunori
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      Nagasaki University
  •  Serial analysis of gene expression in human leukocytesPrincipal Investigator

    • Principal Investigator
      HASHIMOTO Shinichi
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 2004 2003

All Journal Article Presentation Patent

  • [Journal Article] Single-cell RNA sequencing to detect age-associated genes that identify senescent cells in the liver of aged mice2023

    • Author(s)
      Doshida Yuta、Hashimoto Shinichi、Iwabuchi Sadahiro、Takino Yuka、Ishiwata Toshiyuki、Aigaki Toshiro、Ishigami Akihito
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 14186-14186

    • DOI

      10.1038/s41598-023-41352-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K21266, KAKENHI-PROJECT-23K24804
  • [Journal Article] TAS-Seq is a robust and sensitive amplification method for bead-based scRNA-seq.2022

    • Author(s)
      Shichino S, Ueha S, Hashimoto S, Ogawa T, Aoki H, Wu B, Chen CY, Kitabatake M, Ouji-Sageshima N, Sawabata N, Kawaguchi T, Okayama T, Sugihara E, Hontsu S, Ito T, Iwata Y, Wada T, Ikeo K, Sato T, Matsushima K.
    • Journal Title

      Communications Biology

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06391
  • [Journal Article] TAS-Seq is a robust and sensitive amplification method for bead-based scRNA-seq.2022

    • Author(s)
      Shichino S, Ueha S, Hashimoto S, Ogawa T, Aoki H, Wu B, Chen CY, Kitabatake M, Ouji-Sageshima N, Sawabata N, Kawaguchi T, Okayama T, Sugihara E, Hontsu S, Ito T, Iwata Y, Wada T, Ikeo K, Sato T, Matsushima K.
    • Journal Title

      Communications Biology

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Journal Article] Identification of a KLF5-dependent program and drug development for skeletal muscle atrophy2021

    • Author(s)
      Liu L, Koike H, Ono T, Hayashi S, Kudo F, Kaneda A, Kagechika H, Manabe I, Nakashima T, Oishi, Y.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 118 Issue: 35

    • DOI

      10.1073/pnas.2102895118

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03679, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-20H04938, KAKENHI-PUBLICLY-20H04956, KAKENHI-PROJECT-20H00551, KAKENHI-PROJECT-19H03648, KAKENHI-PROJECT-21H03331, KAKENHI-PROJECT-21K06961, KAKENHI-PROJECT-21K19554, KAKENHI-PROJECT-21K17154
  • [Journal Article] Ascorbic acid during the suckling period is required for proper DNA demethylation in the liver2020

    • Author(s)
      Kawahori Kenichi、Kondo Yoshitaka、Yuan Xunmei、Kawasaki Yuki、Hanzawa Nozomi、Tsujimoto Kazutaka、Wada Fumiko、Kohda Takashi、Ishigami Akihito、Yamada Tetsuya、Ogawa Yoshihiro、Hashimoto Koshi
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 21228-21228

    • DOI

      10.1038/s41598-020-77962-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09018, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-19H04043
  • [Journal Article] Age-associated changes in the transcriptomes of non-cultured adipose-derived stem cells from young and old mice assessed via single-cell transcriptome analysis2020

    • Author(s)
      Doshida Yuta、Sano Haruka、Iwabuchi Sadahiro、Aigaki Toshiro、Yoshida Masayuki、Hashimoto Shinichi、Ishigami Akihito
    • Journal Title

      PLOS ONE

      Volume: 15 Issue: 11 Pages: e0242171-e0242171

    • DOI

      10.1371/journal.pone.0242171

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H04043
  • [Journal Article] Mutant KCNJ3 and KCNJ5 potassium channels as novel molecular targets in bradyarrhythmias and atrial fibrillation.2019

    • Author(s)
      Yamada N, Asano Y, Fujita M, Yamazaki S, Inanobe A, Matsuura N, Kobayashi H, Ohno S, Ebana Y, Tsukamoto O, Ishino S, Takuwa A, Kioka H, Yamashita T, Hashimoto N, Zankov DP, Shimizu A, Asakura M, Asanuma H, Kato H, Nishida Y, Miyashita Y, Shinomiya H, Naiki N, Hayashi K, Makiyama T, Ogita H, et al.
    • Journal Title

      Circulation

      Volume: In press Issue: 18 Pages: 2157-2169

    • DOI

      10.1161/circulationaha.118.036761

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08627, KAKENHI-PROJECT-17K08657, KAKENHI-PROJECT-17K09577, KAKENHI-PROJECT-17K09578, KAKENHI-PROJECT-18K07875, KAKENHI-PROJECT-18K08100, KAKENHI-PROJECT-17F17418, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-15KK0302, KAKENHI-PROJECT-17K07251, KAKENHI-PROJECT-18K08033, KAKENHI-PROJECT-19K08538, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H01560, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-17H04018, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H04074, KAKENHI-PROJECT-18H02803, KAKENHI-PROJECT-18H02808, KAKENHI-PROJECT-18K19547, KAKENHI-PROJECT-19H03652
  • [Journal Article] “Nx1-Seq (Well Based Single-Cell Analysis System)”2019

    • Author(s)
      Shinichi Hashimoto
    • Journal Title

      Adv Exp Med Biol.

      Volume: 1129 Pages: 51-61

    • DOI

      10.1007/978-981-13-6037-4_4

    • ISBN
      9789811360367, 9789811360374
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Journal Article] Notch signaling facilitates hepatitis B virus covalently closed circular DNA transcription via cAMP response element-binding protein with E3 ubiquitin ligase-modulation2019

    • Author(s)
      Wang Zijing、Kawaguchi Kazunori、Honda Masao、Hashimoto Shinichi、Shirasaki Takayoshi、Okada Hikari、Orita Noriaki、Shimakami Tetsuro、Yamashita Taro、Sakai Yoshio、Mizukoshi Eishiro、Murakami Seishi、Kaneko Shuichi
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 1621-1621

    • DOI

      10.1038/s41598-018-38139-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09414, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-17K15933, KAKENHI-PROJECT-17K09413, KAKENHI-PROJECT-17H01540
  • [Journal Article] Engraftment and proliferation potential of embryonic lung tissue cells in irradiated mice with emphysema2019

    • Author(s)
      Shiraishi Kazushige、Shichino Shigeyuki、Tsukui Tatsuya、Hashimoto Shinichi、Ueha Satoshi、Matsushima Kouji
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 1-12

    • DOI

      10.1038/s41598-019-40237-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-16K08730, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H01540, KAKENHI-PLANNED-17H06392
  • [Journal Article] “Single-Cell Transcriptome Analysis in Tumor Tissues”2019

    • Author(s)
      Sadahiro Iwabuchi and Shinichi Hashimoto.
    • Journal Title

      Transcriptome Analysis, Intechopen

      Volume: -

    • DOI

      10.5772/intechopen.84558

    • ISBN
      9781789843279, 9781789843286
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Journal Article] Clonal analysis revealed functional heterogeneity in cancer stem-like cell phenotypes in uterine endometrioid adenocarcinoma.2019

    • Author(s)
      Tabuchi Y, Hirohashi Y, Hashimoto S, Mariya T, Asano T, Ikeo K, Kuroda T, Mizuuchi M, Murai A, Uno S, Kawai N, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Saito T, Torigoe T.
    • Journal Title

      Exp Mol Pathol

      Volume: 106 Pages: 78-88

    • DOI

      10.1016/j.yexmp.2018.11.013

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11285, KAKENHI-PLANNED-17H06399, KAKENHI-PROJECT-16H05451, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H01540
  • [Journal Article] Gli signaling pathway modulates fibroblast activation and facilitates scar formation in pulmonary fibrosis2019

    • Author(s)
      Tsukui Tatsuya、Ueha Satoshi、Shichino Shigeyuki、Hashimoto Shinichi、Nakajima Takuya、Shiraishi Kazushige、Kihara Miho、Kiyonari Hiroshi、Inagaki Yutaka、Matsushima Kouji
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 514 Issue: 3 Pages: 684-690

    • DOI

      10.1016/j.bbrc.2019.05.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22627, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-17H04166, KAKENHI-PROJECT-17H01540
  • [Journal Article] TCR Repertoire Analysis Reveals Mobilization of Novel CD8+ T Cell Clones Into the Cancer-Immunity Cycle Following Anti-CD4 Antibody Administration2019

    • Author(s)
      Aoki Hiroyasu、Ueha Satoshi、Shichino Shigeyuki、Ogiwara Haru、Hashimoto Shin-ichi、Kakimi Kazuhiro、Ito Satoru、Matsushima Kouji
    • Journal Title

      Frontiers in Immunology

      Volume: 9 Pages: 3185-3185

    • DOI

      10.3389/fimmu.2018.03185

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H04708, KAKENHI-PROJECT-18H02696, KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-17H01540
  • [Journal Article] Mesenchymal-Epithelial Interactome Analysis Reveals Essential Factors Required for Fibroblast-Free Alveolosphere Formation2019

    • Author(s)
      Shiraishi Kazushige、Shichino Shigeyuki、Ueha Satoshi、Nakajima Takuya、Hashimoto Shinichi、Yamazaki Satoshi、Matsushima Kouji
    • Journal Title

      iScience

      Volume: 11 Pages: 318-333

    • DOI

      10.1016/j.isci.2018.12.022

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05095, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-17H05086, KAKENHI-PROJECT-16K08730, KAKENHI-PLANNED-17H06392
  • [Journal Article] Transcriptome network analysis identifies protective role of the LXR/SREBP-1c axis in murine pulmonary fibrosis.2019

    • Author(s)
      Shichino S, Ueha S, Hashimoto S, Otsuji M, Abe J, Tsukui T, Deshimaru S, Nakajima T, Kosugi-Kanaya M, Shand FH, Inagaki Y, Shimano H, Matsushima K.
    • Journal Title

      JCI Insight.

      Volume: 4(1) Issue: 1 Pages: 122163-122163

    • DOI

      10.1172/jci.insight.122163

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-17H04166, KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-17K19546, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06392
  • [Journal Article] Mesenchymal-epithelial interactome analysis reveals essential factors required for fibroblast-free alveolosphere formation.2019

    • Author(s)
      Shiraishi, K., Shichino, S., Ueha, S., Nakajima, T., Hashimoto, S., Yamazaki, S., Matsushima, K.
    • Journal Title

      iScience

      Volume: 11 Pages: 318-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Journal Article] Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood2018

    • Author(s)
      X Yuan, K Tsujimoto, K Hashimoto, K Kawahori, N Hanzawa, M Hamaguchi, T Seki, M Nawa, T Ehara, Y Kitamura, I Hatada, M Konishi, N Itoh, Y Nakagawa, H Shimano, T Takai-Igarashi, Y Kamei, Y Ogawa.
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 636-636

    • DOI

      10.1038/s41467-018-03038-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K00295, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-17K01840, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-16H05331, KAKENHI-PROJECT-18K11420, KAKENHI-PROJECT-18K18461, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-16H04926, KAKENHI-PROJECT-17H06652
  • [Journal Article] Alveolar macrophages drive hepatocellular carcinoma lung metastasis by generating leukotriene B4.2018

    • Author(s)
      Nosaka T, Baba T, Tanabe Y, Sasaki S, Nishimura T, Imamura Y, Yurino H, Hashimoto S, Arita M, Nakamoto Y, Mukaida N.
    • Journal Title

      J Immunol

      Volume: 200 Issue: 5 Pages: 1839-1852

    • DOI

      10.4049/jimmunol.1700544

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08733, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-17J06054, KAKENHI-PROJECT-17K19681, KAKENHI-PROJECT-17H01540
  • [Journal Article] Lung fibroblasts express a miR-19a-19b-20a sub-cluster to suppress TGF-β-associated fibroblast activation in murine pulmonary fibrosis2018

    • Author(s)
      Souma Kunihiko、Shichino Shigeyuki、Hashimoto Shinichi、Ueha Satoshi、Tsukui Tatsuya、Nakajima Takuya、Suzuki Hiroshi I.、Shand Francis H. W.、Inagaki Yutaka、Nagase Takahide、Matsushima Kouji
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 16642-16642

    • DOI

      10.1038/s41598-018-34839-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-17H04166, KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-17K19546, KAKENHI-PLANNED-17H06392
  • [Journal Article] Comprehensive single-cell transcriptome analysis reveals heterogeneity in endometrioid adenocarcinoma tissues.2017

    • Author(s)
      Hashimoto S, Tabuchi Y, Yurino H, Hirohashi Y, Deshimaru S, Asano T, Mariya T, Oshima K, Takamura Y, Ukita Y, Ametani A, Kondo N, Monma N, Takeda T, Misu S, Okayama T, Ikeo K, Saito T, Kaneko S, Suzuki Y, Hattori M, Matsushima K, et al.
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 1 Pages: 14225-14225

    • DOI

      10.1038/s41598-017-14676-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19546, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-17H01540
  • [Journal Article] Comprehensive single-cell transcriptome analysis reveals heterogeneity in endometrioid adenocarcinoma tissues.2017

    • Author(s)
      Hashimoto S, Tabuchi Y, Yurino H, Hirohashi Y, Deshimaru S, Asano T, Mariya T, Oshima K, Takamura Y, Ukita Y, Ametani A, Kondo N, Monma N, Takeda T, Misu S, Okayama T, Ikeo K, Saito T, Kaneko S, Suzuki Y, Hattori M, Matsushima K, et al.
    • Journal Title

      Sci Rep

      Volume: 27 Pages: 14225-14225

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06391
  • [Journal Article] Lack of IL-6 in the tumor microenvironment augments type-1 immunity and increases the efficacy of cancer immunotherapy.2017

    • Author(s)
      Ohno Y, Toyoshima Y, Yurino H, Monma N, Xiang H, Sumida K, Kaneumi S, Terada S, Hashimoto S, Ikeo K, Homma S, Kawamura H, Takahashi N, Taketomi A, Kitamura H
    • Journal Title

      Cancer Science

      Volume: 108 Issue: 10 Pages: 1959-1966

    • DOI

      10.1111/cas.13330

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10526, KAKENHI-PROJECT-15K08416, KAKENHI-PROJECT-17H01540, KAKENHI-PROJECT-16H05409
  • [Journal Article] Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population.2017

    • Author(s)
      Kawashima M, Honda M, Nakamura M. et al.
    • Journal Title

      Hum Mol Genet.

      Volume: - Pages: 650-659

    • DOI

      10.1093/hmg/ddw406

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26293076, KAKENHI-PROJECT-26293181, KAKENHI-PROJECT-26460416, KAKENHI-PROJECT-26460996, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-15K06908, KAKENHI-PROJECT-15K19314, KAKENHI-PROJECT-16K21069, KAKENHI-PROJECT-17H04058, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-16H05283, KAKENHI-PROJECT-15K19357
  • [Journal Article] Reduced supply of monocyte-derived macrophages leads to a transition from nodular to diffuse lesions and tissue cell activation in silica-induced pulmonary fibrosis in mice.2015

    • Author(s)
      Shigeyuki Shichino, Jun Abe, Satoshi Ueha, Mikiya Otsuji, Tatsuya Tsukui, Mizuha Kosugi-Kanaya, Francis HW Shand, Shin-ichi Hashimoto, Hiroshi I. Suzuki, Teppei Morikawa, Yutaka Inagaki, and Kouji Matsushima:
    • Journal Title

      Am J Pathol

      Volume: 185 Issue: 11 Pages: 2923-2938

    • DOI

      10.1016/j.ajpath.2015.07.013

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15299, KAKENHI-PROJECT-15F15113, KAKENHI-PROJECT-13J05983, KAKENHI-PROJECT-25460491, KAKENHI-PROJECT-25290071, KAKENHI-PROJECT-25293113, KAKENHI-PROJECT-25293179
  • [Journal Article] Associations between nucleosome phasing, sequence asymmetry, and tissue-specific expression in a set of inbred Medaka species.2015

    • Author(s)
      Nakatani Y, Mello CC, Hashimoto S, Shimada A, Nakamura R, Tsukahara T, Qu W, Yoshimura J, Suzuki Y, Sugano S, Takeda H, Fire A, Morishita S.
    • Journal Title

      BMC Genomics

      Volume: 16(1) Issue: 1 Pages: 978-978

    • DOI

      10.1186/s12864-015-2198-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0002, KAKENHI-PROJECT-25290071
  • [Journal Article] A simple but powerful heuristic method for accelerating k-means clustering of large-scale data in life science2014

    • Author(s)
      Kazuki Ichikawa and Shinichi Morishita
    • Journal Title

      IEEE/ACM Transactions on Computational Biology and Bioinformatics(TCBB)

      Volume: (印刷中) Issue: 4 Pages: 681-692

    • DOI

      10.1109/tcbb.2014.2306200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23241058, KAKENHI-PROJECT-221S0002
  • [Journal Article] Lymph Node Stromal Cells Negatively Regulate Antigen-Specific CD4+ T Cell Responses.2014

    • Author(s)
      Abe J, Shichino S, Ueha S, Hashimoto S, Tomura M, Inagaki Y, Stein JV, Matsushima K.
    • Journal Title

      J Immunol.

      Volume: 193 Issue: 4 Pages: 1636-1644

    • DOI

      10.4049/jimmunol.1302946

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-25290071, KAKENHI-PROJECT-25293113, KAKENHI-PROJECT-25293179, KAKENHI-PROJECT-25460491
  • [Journal Article] Bone Marrow Graft-versus-Host Disease: Evaluation of Its Clinical Impact on Disrupted Hematopoiesis after Allogeneic Hematopoietic Stem Cell Transplantation2014

    • Author(s)
      Souichi Shiratori, Mizuha Kosugi-Kanaya, Satoshi Ueha, Junichi Sugita1, Akio Shigematsu, Takeshi Kondo, Daigo Hashimoto, Katsuya Fujimoto, Tomoyuki Endo, Mitsufumi Nishio, Satoshi Hashino, Yoshihiro Matsuno, Kouji Matsushima, Junji Tanaka, Masahiro Imamura, Takanori Teshima
    • Journal Title

      Biol Blood Marrow Transplant

      Volume: 20 Issue: 4 Pages: 495-500

    • DOI

      10.1016/j.bbmt.2013.12.568

    • NAID

      120005427744

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24659216, KAKENHI-PROJECT-25293113, KAKENHI-PROJECT-25293217, KAKENHI-PROJECT-25460491, KAKENHI-PROJECT-25670443, KAKENHI-PROJECT-25860775, KAKENHI-PROJECT-26461438
  • [Journal Article] Pro-inflammatory/Th1 gene expression shift in high glucose stimulated mesangial cells and tubular epithelial cells.2014

    • Author(s)
      Iwata Y, Furuichi K, Hashimoto S, Yokota K, Yasuda H, Sakai N, Kitajima S, Toyama T, Shinozaki Y, Sagara A, Matsushima K, Kaneko S, Wada T.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 443 Issue: 3 Pages: 969-974

    • DOI

      10.1016/j.bbrc.2013.12.072

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24406028, KAKENHI-PROJECT-24591192, KAKENHI-PROJECT-25290071, KAKENHI-PROJECT-25670269, KAKENHI-PROJECT-26293126, KAKENHI-PROJECT-26293127
  • [Journal Article] A unique dermal dendritic cell subset that skews the immune response toward Th2.2013

    • Author(s)
      2.Murakami R, Denda-Nagai K, Hashimoto S, Nagai S, Hattori M, Irimura T.
    • Journal Title

      PLoS One.

      Volume: 8 Issue: 9 Pages: e73270-e73270

    • DOI

      10.1371/journal.pone.0073270

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23689009, KAKENHI-PROJECT-24790479, KAKENHI-PROJECT-25290071
  • [Journal Article] The transcription start site landscape of C. elegans2013

    • Author(s)
      Saito TL, Hashimoto S, Gu SG, Morton JJ, Stadler M, Blumenthal T, Fire A, Morishita S
    • Journal Title

      Genome Research

      Volume: 23(8) Issue: 8 Pages: 1348-61

    • DOI

      10.1101/gr.151571.112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23241058, KAKENHI-PROJECT-25290071
  • [Journal Article] Qualitative Rather than Quantitative Changes Are Hallmarks of Fibroblasts in Bleomycin-Induced Pulmonary Fibrosis2013

    • Author(s)
      Tatsuya Tsukui, Satoshi Ueha, Jun Abe, Shin-ichi Hashimoto, Shigeyuki Shichino, Takeshi Shimaoka, Francis H. W. Shand, Yasuka Arakawa, Kenshiro Oshima, Masahira Hattori, Yutaka
    • Journal Title

      The American Journal of Pathology

      Volume: 3 Issue: 3 Pages: 758-773

    • DOI

      10.1016/j.ajpath.2013.06.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J05983, KAKENHI-PROJECT-24659376, KAKENHI-PROJECT-24790374, KAKENHI-PROJECT-25290071, KAKENHI-PROJECT-25293179, KAKENHI-PROJECT-25460491
  • [Journal Article] Coordinated Changes in DNA Methylation in Antigen-Specific Memory CD4 T Cells2013

    • Author(s)
      Hashimoto S, Ogoshi K, Sasaki A, Abe J, Qu W, Nakatani Y, Ahsan B, Oshima K, Shand FH, Ametani A, Suzuki Y, Kaneko S, Wada T, Hattori M, Sugano S,Morishita S, Matsushima K
    • Journal Title

      J Immunol

      Volume: 190 Issue: 8 Pages: 4076-4091

    • DOI

      10.4049/jimmunol.1202267

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390095, KAKENHI-PROJECT-23241058, KAKENHI-PROJECT-24406028, KAKENHI-PROJECT-24659216, KAKENHI-PROJECT-25290071, KAKENHI-PROJECT-25293113, KAKENHI-PROJECT-25670269, KAKENHI-PLANNED-22129008
  • [Journal Article] Genome-wide genetic variations are highly correlated with proximal DNA methylation patterns2012

    • Author(s)
      Qu W, Hashimoto S, Shimada A, Nakatani Y, Ichikawa K, Saito TL, Ogoshi K, Matsushima K, Suzuki Y, Sugano S, Takeda H, Morishita S.
    • Journal Title

      Genome Res

      Volume: 22 Issue: 8 Pages: 1419-1425

    • DOI

      10.1101/gr.140236.112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390095, KAKENHI-PROJECT-23241058, KAKENHI-ORGANIZER-22129001, KAKENHI-PROJECT-221S0002
  • [Journal Article] Genome-wide characterization of transcriptional start sites in humans by integrative transcriptome analysis2011

    • Author(s)
      Yamashita, R., Sathira, N. P., Kanai, A., Tanimoto, K., Arauchi, T., Tanaka, Y., Hashimoto, S., Sugano, S., Nakai, K., and Suzuki, Y.
    • Journal Title

      Genome Res

      Volume: 21 Pages: 775-789

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21510202
  • [Journal Article] Genome-wide profiling of DNA methylation in human cancer cells2011

    • Author(s)
      Katsumi Ogoshi, et al
    • Journal Title

      Genomics

      Volume: 98 Issue: 4 Pages: 280-287

    • DOI

      10.1016/j.ygeno.2011.07.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059004, KAKENHI-PROJECT-22390095, KAKENHI-PROJECT-23241058
  • [Journal Article] Genome wide profiling of DNA methylation in human cancer cells2011

    • Author(s)
      Ogoshi, K., Hashimoto, S., Nakai, K., Qu, W., Oshima, K., Tokunaga, K., Sugano, S., Hattrori, M., Morishita, S., and Matsushima, K.
    • Journal Title

      Genomics

      Volume: 98 Pages: 280-287

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21510202
  • [Journal Article] Comprehensive gene expression analysis of 5'-end of mRNA identified novel intronic transcripts associated with hepatocellular carcinoma2010

    • Author(s)
      Hodo, Y., Hashimoto, S., Honda, M., Yamashita, T., Suzuki, Y., Sugano, S., Kaneko, S., and Matsushima, K.
    • Journal Title

      Genomics

      Volume: 95 Pages: 217-223

    • NAID

      120002086414

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21510202
  • [Journal Article] High-resolution analysis of the 5'-end transcriptome using a next generation DNA sequencer.2009

    • Author(s)
      Hashimoto, S., et al.
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21510202
  • [Journal Article] Efficient frequency-based de novo short-read clustering for error trimming in next-generation sequencing2009

    • Author(s)
      Qu, W., Hashimoto, S., and Morishita, S.
    • Journal Title

      Genome Res 19

      Pages: 1309-1315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21510202
  • [Journal Article] High-resolution analysis of the 5'-end transcriptome using a next generation DNA sequencer.2009

    • Author(s)
      橋本 真一
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209016
  • [Journal Article] Genome-wide high-resolution transcriptional start sites mapping of cells under hypoxia condition2009

    • Author(s)
      Tsuchihara, K., Suzuki, Y., Wakaguri, H., Irie, T., Hashimoto, S., Matsushima, K., Mizushima-Sugano, J., Yamashita, R., Nakai, K., Bentley, D., Esumi, H., and Sugano, S.
    • Journal Title

      Nucleic Acids Res

      Volume: 37 Pages: 2249-2263

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21510202
  • [Journal Article] High-resolution analysis of the 5'-end transcriptome using a next generation DNA sequencer2009

    • Author(s)
      Hashimoto S, Qu W, Ahsan B, Ogoshi K, Sasaki A, Nakatani Y, Lee Y, Ogawa M, Ametani A, Suzuki Y, Sugano S, Lee CC, Nutter RC, Morishita S, Matsushima K.
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17020002
  • [Journal Article] High-resolution analysis of the 5'-end transcriptome using a next generation DNA sequencer2009

    • Author(s)
      Hashimoto, S., Qu, W., Ahsan, B., Ogoshi, K., Sasaki, A., Nakatani, Y., Lee, Y., Ogawa, M., Ametani, A., Suzuki, Y., Sugano, S., Lee, C. C., Nutter, R. C., Morishita, S., and Matsushima, K.
    • Journal Title

      PLoS One 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21510202
  • [Journal Article] High-resolution analysis of the 5'-end transcriptome using a next generation DNA sequencer2009

    • Author(s)
      Hashimotoら
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17020002
  • [Journal Article] Chromatin-associated periodicity in genetic variation downstream of transcriptional start sites2009

    • Author(s)
      Sasaki, S., Mello, C. C., Shimada, A., Nakatani, Y., Hashimoto, S., Ogawa, M., Matsushima, K., Gu, S. G., Kasahara, M., Ahsan, B., Sasaki, A., Saito, T., Suzuki, Y., Sugano, S., Kohara, Y., Takeda, H., Fire, A., and Morishita, S.
    • Journal Title

      Science

      Volume: 323 Pages: 401-404

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21510202
  • [Journal Article] High-resolution analysis of the 5'-end transcriptome using a next generation DNA sequencer.2009

    • Author(s)
      Hashimoto S, Qu W, Ahsan B, Ogoshi K,Sasaki A, Nakatani Y, Lee Y, Ogawa M,Ametani A, Suzuki Y, Sugano S, Lee CC,Nutter RC, Morishita S,Matsushima K
    • Journal Title

      PLoS ONE 4(1)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209016
  • [Journal Article] Chromatin-associated periodicity in genetic variation downstream of transcriptional start sites.2009

    • Author(s)
      Sasaki S, Mello CC, Shimada A, Nakatani Y,Hashimoto S, Ogawa M, Matsushima K, Gu SG,Kasahara M, Ahsan B, Sasaki A, Saito T,Suzuki Y, Sugano S, Kohara Y, Takeda H, Fire A, Morishita S
    • Journal Title

      Science 323(5912)

      Pages: 401-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209016
  • [Journal Article] Large-scale analysis of Macaca fascicularis transcripts and inference of genetic divergence between M. fascicularis and M. mulatta.2008

    • Author(s)
      Osada N, Hashimoto K, Kameoka Y, Hirata M, Tanuma R, Uno Y, Inoue I, Hida M, Suzuki Y, Sugano S, Terao K, Kusuda J, Takahashi I.
    • Journal Title

      BMC Genomics 9

      Pages: 90-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17020002
  • [Journal Article] SAGE application in hematological research.2008

    • Author(s)
      Hashimoto S, Matsushima K
    • Journal Title

      Curr Pharm Biotechnol 9(5)

      Pages: 383-391

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209016
  • [Journal Article] The medaka draft genome and insights into vertebrate genome evolution2007

    • Author(s)
      Kasahara M, Naruse K, Sasaki S, Nakatani Y, Qu W, Ahsan B, Yamada T, Nagayasu Y, Doi K, Kasai Y, Jindo T, Kobayashi D, Shimada A, Toyoda A, Kuroki Y, Fujiyama A, Sasaki T, Shimizu A, Asakawa S, Shimizu N,Hashimoto S, Yang J, Lee Y, Matsushima K,Sugano S, Sakaizumi M, Narita T, Ohishi K,Haga S, Ohta F, Nomoto H, Nogata K,Morishita T, Endo T, Shin-I T, Takeda H,Morishita S, Kohara Y
    • Journal Title

      Nature 447(7145)

      Pages: 714-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209016
  • [Journal Article] Intrinsic Promoter Activities of Primary DNA Sequences in the Human Genome.2007

    • Author(s)
      Sakakibara Y, Irie T, Suzuki Y, Yamashita R, Wakaguri H, Kanai A, Chiba J, Takagi T, Mizushima-Sugano J, Hashimoto SI, Nakai K, Sugano S.
    • Journal Title

      DNA Res. 14

      Pages: 71-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17020002
  • [Journal Article] Substitution Rate and Structural Divergence of 5'UTR Evolution: Comparative Analysis Between Human and Cynomolgus Monkey cDNAs2005

    • Author(s)
      Osada N, Hirata M, Tanuma R, Kusuda J, Hida M, Suzuki Y, Sugano S, Gojobori T, Shen CK, Wu CI, Hashimoto K.
    • Journal Title

      Mol Biol Evol. 22

      Pages: 1976-1982

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17020002
  • [Journal Article] 5'-end SAGE for the analysis of transcriptional start sites.2004

    • Author(s)
      Hashimoto, S.-i.et al.
    • Journal Title

      Nat Biotechnol 22

      Pages: 1146-1149

    • Data Source
      KAKENHI-PROJECT-14013010
  • [Journal Article] 5'-end SAGE for the analysis of transcriptional start sites.2004

    • Author(s)
      Hashimoto S., et al.
    • Journal Title

      Nat Biotechnol 22

      Pages: 1146-1149

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14013010
  • [Journal Article] 5'-end SAGE for the analysis of transcriptional start sites.2004

    • Author(s)
      Hashimoto, et al.
    • Journal Title

      Nat Biotechnol 22

      Pages: 1146-1149

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013010
  • [Journal Article] Gene expression profile inhuman leukocytes.2003

    • Author(s)
      Hashimoto, S. I., et al.
    • Journal Title

      Blood 101

      Pages: 3509-3513

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013010
  • [Journal Article] Gene expression profile in human leukocytes.2003

    • Author(s)
      Hashimoto S., et al.
    • Journal Title

      Blood 101

      Pages: 3509-3513

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14013010
  • [Journal Article] LPS-inducible gene expression profile in human monocytes.2003

    • Author(s)
      Hashimoto, S.-i., et al.
    • Journal Title

      Scand J Infect Dis. 35

      Pages: 619-627

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013010
  • [Journal Article] LPS-inducible gene expression profile In human monocytes.2003

    • Author(s)
      Hashimoto S., et al.
    • Journal Title

      Scand J Infect Dis. 35

      Pages: 619-627

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14013010
  • [Patent] 組織の核酸の構成を解析するための解析プレート2023

    • Inventor(s)
      橋本 真一、岩淵禎弘、今福匡司
    • Industrial Property Rights Holder
      和歌山県立医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2023-099093
    • Filing Date
      2023
    • Data Source
      KAKENHI-PROJECT-21H02790
  • [Patent] 抗B型肝炎ウイルス薬2015

    • Inventor(s)
      橋本 真一、金子 周一、本多 政夫、白崎 尚芳、山下 太郎
    • Industrial Property Rights Holder
      橋本 真一、金子 周一、本多 政夫、白崎 尚芳、山下 太郎
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-219183
    • Filing Date
      2015-11-09
    • Data Source
      KAKENHI-PROJECT-25290071
  • [Patent] 単一細胞由来核酸の解析方法2014

    • Inventor(s)
      橋本真一、金子周一、松島綱治
    • Industrial Property Rights Holder
      橋本真一、金子周一、松島綱治
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-095011
    • Filing Date
      2014-05-02
    • Data Source
      KAKENHI-PROJECT-25290071
  • [Presentation] シングルセル解析を用いた老齢マウス肝臓での老化肝細胞の指標となる遺伝子の同定.2023

    • Author(s)
      土志田裕太、橋本真一、岩淵禎弘、滝野有花、石渡俊行、相垣敏郎、石神昭人
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] Identification of age-associated genes in liver of aged mice.2023

    • Author(s)
      Yuta Doshida, Shinichi Hashimoto, Sadahiro Iwabuchi, Yuka Takino, Toshiyuki Ishiwata, Toshiro Aigaki, Akihito Ishigami
    • Organizer
      IAGG Asia/Oceania Regional Congress 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] ドキソルビシンによる老化誘導が老化関連遺伝子の発現に及ぼす影響.2023

    • Author(s)
      土志田裕太、橋本真一、岩淵禎弘、滝野有花、石渡俊行、相垣敏郞、石神昭人
    • Organizer
      日本基礎老化学会第46回大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] Identification of Akr1c6 gene associated with SMP30 gene expression in mouse liver.2022

    • Author(s)
      Yurika NIIMURA, Yuta DOSHIDA, Fumiya SOBUE, Koji FUKUI, Toshiro AIGAKI, Sadahiro IWABUCHI, Shinichi HASHIMOTO, Jaewon LEE, Akihito ISHIGAMI
    • Organizer
      日本基礎老化学会第45回大会
    • Data Source
      KAKENHI-PROJECT-23K24804
  • [Presentation] 1細胞トランスクリプトーム手法と炎症細胞解析への適用2020

    • Author(s)
      橋本 真一
    • Organizer
      情報計算化学生物学会(CBI学会)関西部会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] Single-cell RNA sequencing identifies the common and unique cell population between in an in vitro and in vivo cultured condition.2019

    • Author(s)
      Iwabuchi Sadahiro, Shinichi Hashimoto
    • Organizer
      Cold Spring Harbor Laboratory meeting,Single Cell Analysis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] 新規高感度包括的1細胞トランスクリプトーム法の開発と線維化肺における解析2019

    • Author(s)
      七野成之, 橋本真一, 上羽悟史, 北畠正大, 伊藤利洋, 松島綱治
    • Organizer
      第5回骨免疫学会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] Comparison of the gene expression profile in the different cultured condition by single cell transcriptome analysis.2019

    • Author(s)
      Sadahiro Iwabuchi, Shinichi Hashimoto
    • Organizer
      Cold Spring Harbor Laboratory meeting,The Biology of Genomes
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] 1細胞解析による生物学と疾患の新たな理解2019

    • Author(s)
      橋本 真一
    • Organizer
      第36回和漢医薬学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] シングルセル解析による原発性胆汁性胆管炎の解析2019

    • Author(s)
      髙橋 健太、岩淵 禎弘、 橋本 真一、 原田 憲一
    • Organizer
      第56回日本消化器免疫学会総会
    • Data Source
      KAKENHI-PROJECT-17H04058
  • [Presentation] ブレオマイシン誘導マウス肺線維症モデルにおける経時的1細胞トランスクリプトーム解析.2019

    • Author(s)
      七野成之, 橋本真一, 上羽悟史, 松島綱治.
    • Organizer
      第18回分子予防環境医学研究会大会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] 20.ブレオマイシン誘導マウス肺線維症モデルにおける経時的1細胞トランスクリプトーム解析2019

    • Author(s)
      七野成之, 橋本真一, 上羽悟史, 松島綱治
    • Organizer
      第18回分子予防環境医学研究会大会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] Mesenchymal-epithelial interactome analysis during alveologenesis revealed essential factors required for fibroblast-free mouse alveolosphere formation and human alveolar type 2 cell monoculture2019

    • Author(s)
      Kazushige Shiraishi, Shigeyuki Shichino, Takuya Nakajima, Satoshi Ueha, Shinichi Hashimoto, Satoshi Yamazaki, Kouji Matsushima
    • Organizer
      Gordon Research Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] Cell type and marker gene prediction for single-cell transcriptome analysis2019

    • Author(s)
      Shinichi Hashimoto
    • Organizer
      1st International Symposium on Inflammation Cellular Sociology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] Single-cell Gene Expression Analysis in Tumor Microenvironment2019

    • Author(s)
      Shinichi Hashimoto
    • Organizer
      EMBO single cell work shop
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] Single-cell transcriptome analysis reveals the gene exchange of cancer cells with high malignant potential and immune cells in endometrioid adenocarcinoma tissues.2019

    • Author(s)
      Hashimoto S.
    • Organizer
      Single cell biology meets diagnostics workshop
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] Single-cell transcriptome identifies cytokine/chemokine expression signatures of lung cell subsets in murine pulmonary fibrosis2018

    • Author(s)
      Shigeyuki Shichino, Shin-ichi Hashimoto, Satoshi Ueha, Kouji Matsushima.
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] Single-cell gene expression analysis in gynecological cancer.2018

    • Author(s)
      Hashimoto S.
    • Organizer
      HCA Asia Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] 16.Single-cell transcriptome identifies cytokine/chemokine expression signatures of lung cell subsets in murine pulmonary fibrosis2018

    • Author(s)
      Shigeyuki Shichino, Shin-ichi Hashimoto, Satoshi Ueha, Kouji Matsushima
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] ingle-cell transcriptome analysis reveals the gene exchange of cancer cells with high malignant potential and immune cells.2018

    • Author(s)
      Hashimoto S, Tabuchi Y, Torigoe T, Iwabuchi S.
    • Organizer
      ASHG 2018 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] 担がんマウスにおけるCD8+ T細胞レパトアの臓器別解析2018

    • Author(s)
      七野 成之, 青木 寛泰, 橋本 真一, 荻原 春, 上羽 悟史, 松島 綱治
    • Organizer
      第17回分子予防環境医学研究会大会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2018

    • Author(s)
      Satoshi Ueha, Aoki Hiroyasu, Shigeyuki Shichino, Ogiwara Haru, Shinichi Hashimoto, Kazuhiro Kakimi, Kouji Matsushima
    • Organizer
      Keystone Symposia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] Single-cell transcriptomeによるマウス線維化肺のサイト カイン・ケモカイン発現プロファイルの解明2018

    • Author(s)
      七野成之, 橋本真一, 上羽悟史, 松島綱治
    • Organizer
      第83回日本インターフェロン・サイトカイン学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] 10.Single-cell transcriptomeによるマウス線維化肺のサイト カイン・ケモカイン発現プロファイルの解明2018

    • Author(s)
      七野成之, 橋本真一, 上羽悟史, 松島綱治
    • Organizer
      第83回日本インターフェロン・サイトカイン学会学術集会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] がん微小環境における1細胞遺伝子発現解析2018

    • Author(s)
      橋本真一
    • Organizer
      第77回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2018

    • Author(s)
      Satoshi Ueha, Aoki Hiroyasu, Shigeyuki Shichino, Ogiwara Haru, Shinichi Hashimoto, Kazuhiro Kakimi, Kouji Matsushima
    • Organizer
      Keystone Symposia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] 細胞と分子の動きから観る臓器線維化2018

    • Author(s)
      七野 成之, 津久井 達也, 橋本 真一, 大辻 幹哉, 上羽 悟史, 稲垣 豊, 島野 仁, 松島 綱治
    • Organizer
      「炎症の慢性化機構の解明と制御に向けた基盤技術の創出」研究開発領域公開シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] Identification of a functional and transcriptional signature for tumor-infiltrating dendritic cells in mouse2017

    • Author(s)
      Satoshi Ueha, Haru Ogiwara, Shigeyuki Shichino, Jun Abe, Francis Shand, Shinichi Hashimoto, Kouji Matsushima
    • Organizer
      5th Annual Meeting of the International Cytokine and Interferon Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+ T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Yasuhiro Aoki, Shigeyuki Shichino, Haru Ogiwara, Shinichi Hashimoto, Kazuhiro Kakimi, Satoru Ito, Kouji Matsushima
    • Organizer
      第21回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] An organ-wide transcriptome of stromal cells identifies the core signature of steady-state murine fibroblasts2017

    • Author(s)
      Shigeyuki SHICHINO, Satoshi UEHA, Shin-ichi HASHIMOTO, Inagaki YUTAKA, Kouji MATSUSHIMA
    • Organizer
      4th Lymphoid tissue meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] 担がんマウスにおけるCD8+ T細胞レパトアの臓器別解析2017

    • Author(s)
      青木 寛泰、七野 成之、橋本 真一、上羽 悟史、松島 綱治
    • Organizer
      第3回日本骨免疫学会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] 肺線維症における活性化線維芽細胞の起源とその活性化制御機構2017

    • Author(s)
      七野 成之, 上羽 悟史, 橋本 真一, 松島 綱治
    • Organizer
      第38回日本炎症・再生医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+ T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Yasuhiro Aoki, Shigeyuki Shichino, Haru Ogiwara, Shinichi Hashimoto, Kazuhiro Kakimi, Satoru Ito, Kouji Matsushima
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Aoki Hiroyasu, Shigeyuki Shichino, Ogiwara Haru, Shinichi Hashimoto, Kazuhiro Kakimi, Kouji Matsushima
    • Organizer
      The 46th Japanese Society for Immunology
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+ T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Yasuhiro Aoki, Shigeyuki Shichino, Haru Ogiwara, Shinichi Hashimoto, Kazuhiro Kakimi, Satoru Ito, Kouji Matsushima
    • Organizer
      第21回日本がん免疫学会総会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] Transcriptome analysis reveals PDGF signaling-dependent regulation of myelofibrosis in murine chronic graft-versus-host diseases2017

    • Author(s)
      Shigeyuki Shichino, Satoshi Ueha, Naoto Sudo, Mizuha Kosugi-Kanaya, Francis HW Shand, Teppei Morikawa, Shin-ichi Hashimoto, Takanori Teshima, Kouji Matsushima
    • Organizer
      5th Annual Meeting of the International Cytokine and Interferon Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+ T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Yasuhiro Aoki, Shigeyuki Shichino, Haru Ogiwara, Shinichi Hashimoto, Kazuhiro Kakimi, Satoru Ito, Kouji Matsushima
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] 担がんマウスにおけるCD8+ T細胞レパトアの臓器別解析2017

    • Author(s)
      青木 寛泰、七野 成之、橋本 真一、上羽 悟史、松島 綱治
    • Organizer
      第3回日本骨免疫学会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] Transcriptome network analysis reveals lipid-related transcription factors as hubs for fibroblast activation in murine pulmonary fibrosis2017

    • Author(s)
      Shigeyuki Shichino, Satoshi Ueha, Inagaki Yutaka, Shin-ichi Hashimoto, Hitoshi Shimano, and Kouji Matsushima
    • Organizer
      The 19th Takeda Science Foundation Symposium on Bioscience : Chronic Inflammation - initiation, Progression and Resolution
    • Place of Presentation
      武田薬品研修所(大阪府吹田市)
    • Year and Date
      2017-01-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] Identification of a functional and transcriptional signature for tumor-infiltrating dendritic cells in mouse2017

    • Author(s)
      Satoshi Ueha, Haru Ogiwara, Shigeyuki Shichino, Jun Abe, Francis Shand, Shinichi Hashimoto, Kouji Matsushima
    • Organizer
      5th Annual Meeting of the International Cytokine and Interferon Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Aoki Hiroyasu, Shigeyuki Shichino, Ogiwara Haru, Shinichi Hashimoto, Kazuhiro Kakimi, Kouji Matsushima
    • Organizer
      The 46th Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] Reduced Supply of Monocyte-derived Macrophages Leads to a Transition from Nodular to Diffuse Lesions and Tissue Cell Activation in Silica-induced Pulmonary Fibrosis in Mice2016

    • Author(s)
      Shigeyuki Shichino, Jun Abe, Tatsuya Tsukui, Satoshi Ueha, Shin-ichi Hashimoto, Teppei Morikawa, Yutaka Inagaki, and Kouji Matsushima
    • Organizer
      Keystone symposia, Fibrosis: From Basic Mechanisms to Targeted Therapies (Q3)
    • Place of Presentation
      Keystone Resort. Colorado, USA
    • Year and Date
      2016-02-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293113
  • [Presentation] 多臓器間網羅的トランスクリプトーム解析による線維芽細胞 core transcriptomic signatureの同定2016

    • Author(s)
      七野成之, 上羽悟史, 橋本真一, 松島綱治
    • Organizer
      第2回日本骨免疫学会
    • Place of Presentation
      ホテルモントレ沖縄スパ&リゾート(沖縄県国頭郡)
    • Year and Date
      2016-07-06
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] An organ-wide transcriptome of collagen-producing cells identifies the core signature of steady-state murine fibroblasts2016

    • Author(s)
      "Shigeyuki SHICHINO, Satoshi UEHA, Shin-ichi HASHIMOTO, Inagaki YUTAKA and Kouji MATSUSHIMA"
    • Organizer
      第45回日本免疫学会学術集会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県宜野湾市)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] Global transcriptome analysis reveals the expression signatures of cell surface receptors in the lung tissue cell subsets2015

    • Author(s)
      Shigeyuki Shichino, Tatsuya Tsukui, Satoshi Ueha, Yutaka Inagaki, Shin-ichi Hashimoto, and Kouji Matsushima
    • Organizer
      第44回日本免疫学会学術集会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-25293113
  • [Presentation] Comprehensive single-cell transcriptome reveals heterogeneity in cancer tissue2015

    • Author(s)
      Shinichi Hashimoto
    • Organizer
      Cold Spring Harbor Laboratory, Single cell meeting
    • Place of Presentation
      Cold Spring Harbor Laboratory
    • Year and Date
      2015-11-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25290071
  • [Presentation] Global transcriptome analysis reveals the expression signatures of cell surface receptors in the lung tissue cell subsets in mice2015

    • Author(s)
      Shigeyuki Shichino, Tatsuya Tsukui, Satoshi Ueha, Yutaka Inagaki, Shin-ichi Hashimoto, and Kouji Matsushima
    • Organizer
      International Conference of Cancer Immunotherapy and Macrophages
    • Place of Presentation
      Ion International Research center, Tokyo, Japan
    • Year and Date
      2015-07-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293113
  • [Presentation] がん組織における包括的1細胞遺伝子発現解析2015

    • Author(s)
      鳥越俊彦、橋本真一
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25290071
  • [Presentation] MiR-449 induced by HDACi in colon cancer cell lines mediated cell death2011

    • Author(s)
      橋本
    • Organizer
      第70回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-21510202
  • [Presentation] MiR-449 induced by HDACi in colon cancer cell lines mediated cell death2011

    • Author(s)
      橋本真一, ら
    • Organizer
      第70回日本癌学会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-21510202
  • [Presentation] The 5' -end transcriptome and methylome in murine memory CD4+ T cells2010

    • Author(s)
      Hashimoto Shinichi
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe, Japan (Kobe Convention Center)
    • Year and Date
      2010-08-25
    • Data Source
      KAKENHI-PLANNED-19059004
  • [Presentation] Gene expression and DNA methylation profiling in a cancer cell line treated with TSA using second generation sequencer2009

    • Author(s)
      Shin-ichi Hashimoto
    • Organizer
      第68回 日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-21510202
  • [Presentation] Gene expression and DNA methylation profiling in a ca cer cell line treated with TSA using secend generation sequencer2009

    • Author(s)
      橋本
    • Organizer
      第68回日本癌学会学術集会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2009-10-12
    • Data Source
      KAKENHI-PROJECT-21510202
  • 1.  MATSUSHIMA Kouji (50222427)
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    # of Collaborated Products: 45 results
  • 2.  UEHA Satoshi (00447385)
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  • 5.  KAKIMI Kazuhiro (80273358)
    # of Collaborated Projects: 3 results
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  • 6.  YOSHIMINE Hiroyuki (30304950)
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 0 results
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