Okuda Takashi 奥田隆志

… Alternative Names

OKUDA Takashi 奥田隆志

奥田隆志オクダタカシ

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Researcher Number	00322040
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 薬学部(芝共立), 准教授
Affiliation (based on the past Project Information) *help	2013 – 2015: 慶應義塾大学, 薬学部, 准教授 2008 – 2012: 慶應義塾大学, 薬学部, 講師 2001 – 2002: 東京大学, 大学院・医学系研究科, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Biological Sciences Except Principal Investigator Neurochemistry/Neuropharmacology
Keywords	Principal Investigator コリントランスポーター / アセチルコリン / エンドサイトーシス / トラフィッキング / コリン作動性神経 / 免疫組織化学 / 単一塩基多型 / トランスポーター / コリン / 小胞トランスポーター … More / シグナル配列 / 小胞型トランスポーター / オリゴマー / トポロジー / アセチルコリン合成 / 細胞内移行 / 高親和性コリントランスポーター / 認知症 … More Except Principal Investigator アセチルコリン / ニコチン受容体 / トランスポーター / 認知症 / 神経創薬 Less

Regulatory mechanisms for endocytosis of presynaptic moleculesPrincipal Investigator
- Principal Investigator
  
  Okuda Takashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Keio University
A novel cholinergic enhancer and its mechanism of actionPrincipal Investigator
- Principal Investigator
  
  OKUDA Takashi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Keio University
Investigation of a novel mechanism of cholinergic activation for cognitive impairment treatmentPrincipal Investigator
- Principal Investigator
  
  OKUDA Takashi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Keio University
Development of novel drugs for improving cognitive impairment
- Principal Investigator
  
  MISAWA Hidemi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Keio University
高親和性コリントランスポーターの機能調節Principal Investigator
- Principal Investigator
  
  奥田隆志
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
高親和性コリン取り込みによるアセチルコリン合成制御Principal Investigator
- Principal Investigator
  
  奥田隆志
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The University of Tokyo

All 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] 神経変性疾患と創薬、新しい薬学事典2012
- Author(s)
  奥田隆志
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23790097
[Book] コリン作動性神経機能素子の制御機構、基礎老化研究36 (3)2012
- Author(s)
  奥田隆志
- Data Source
  KAKENHI-PROJECT-23790097
[Book] 高親和性コリントランスポーターの局在と機能、Clinical Neuroscience 302012
- Author(s)
  奥田隆志
- Data Source
  KAKENHI-PROJECT-23790097
[Journal Article] Osteopontin is an alpha motor neuron marker in the mouse spinal cord2012
- Author(s)
  Misawa H., et al., 他5名
- Journal Title
  
  J.Neurosci.Res.
  
  Volume: 90 Issue: 4 Pages: 732-742
- DOI
  10.1002/jnr.22813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390274, KAKENHI-PLANNED-23111006, KAKENHI-PROJECT-23790097
[Journal Article] Transmembrane topology and oligomeric structure of the high-affinity choline transporter2012
- Author(s)
  Okuda, T., Osawa, C., Yamada, H., Hayashi, K., Nishikawa, S., Ushio, T., Kubo, Y., Satou, M., Ogawa, H., and Haga, T
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Pages: 42826-42834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790097
[Journal Article] Transmembrane topology and oligomeric structure of the high-affinity choline transporter.2012
- Author(s)
  Okuda, T.
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 287 Issue: 51 Pages: 42826-42834
- DOI
  10.1074/jbc.m112.405027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770149, KAKENHI-PROJECT-23790097
[Journal Article] Osteopontin is an alpha motor neuron marker in the mouse spinal cord.2012
- Author(s)
  Misawa, H., Hara, M., Tanabe S., Niikura, M., Moriwaki, Y., and Okuda, T
- Journal Title
  
  J. Neurosci. Res
  
  Volume: 90 Pages: 732-742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790097
[Journal Article] Substrate-induced internalization of the high-affinity choline transporter2011
- Author(s)
  Okuda T., et al., 他3名
- Journal Title
  
  J.Neurosci.
  
  Volume: 31 Issue: 42 Pages: 14989-14997
- DOI
  10.1523/jneurosci.2983-11.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390274, KAKENHI-PLANNED-23111006, KAKENHI-PROJECT-23790097
[Journal Article] Substrate-induced internalization of the high-affinity choline transporter2011
- Author(s)
  Okuda, T., Konishi, A., Misawa, H., and Haga, T
- Journal Title
  
  J. Neurosci.
  
  Volume: 87 Pages: 3024-3032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790097
[Journal Article] Expression of SLURP-1, an endogenous alpha7 nicotinic acetylcholine receptor allosteric ligand, in murine bronchial epithelial cells.2009
- Author(s)
  Horiguchi, K., Horiguchi, S., Yamashita, N., Irie, K., Masuda, J., Takano-Ohmuro, H., Himi, T., Miyazawa, M., Moriwaki, Y., Okuda, T., Misawa, H., Ozak,i H., Kawashima, K.
- Journal Title
  
  J.Neurosci.Res. 87
  
  Pages: 2740-2747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790091
[Journal Article] Primary sensory neuronal expression of SLURP-1, an endogenous nicotinic acetylcholine receptor ligand.2009
- Author(s)
  Moriwaki, Y., Watanabe, Y., Shinagawa, T., Kai, M., Miyazawa, M., Okuda, T., Kawashima, K., Yanbashi, A., Waguri, S., Misawa, H.
- Journal Title
  
  Neurosci.Res. 64
  
  Pages: 403-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500340
[Journal Article] Acetylcholine synthesis and release in NIH3T3 cells coexpressing the high-affinity choline transporter and choline acetyltransferase.2009
- Author(s)
  Fujii, T., Masai, M., Misawa, H., Okuda, T., Takada-Takatori, Y., Moriwaki, Y., Haga, T., Kawashima, K.
- Journal Title
  
  J.Neurosci.Res. 87
  
  Pages: 3024-3032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790091
[Journal Article] Primary sensory neuronal expression of SLURP-1, an endogenous nicotinic acetylcholine receptor ligand.2009
- Author(s)
  Moriwaki, Y., Watanabe, Y., Shinagawa, T., Kai, M., Miyazawa, M., Okuda, T., Kawashima, K., Yabashi, A., Waguri, S., Misawa, H.
- Journal Title
  
  Neurosci.Res. 64
  
  Pages: 403-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790091
[Journal Article] Expression of SLURP-1, an endogenous alpha7 nicotinic acetylcholine receptor allostreric ligand, in murine bronchial epithelial cells.2009
- Author(s)
  Horiguchi, K., Horiguchi, S., Yamashita, N., Irie, K., Masuda, J., Takano-Ohmuro, H., Himi, T., Miyazawa, M., Moriwaki, Y., Okuda, T., Misawa, H., Ozaki, H., Kawashima, K.
- Journal Title
  
  J.Neurosci.Res. 87
  
  Pages: 2740-2747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500340
[Journal Article] Aberrant trafficking of the high-affinity choline transporter in AP-3-deficient mice2008
- Author(s)
  Misawa, H., Fujigaya, H., Nishimura, T., Moriwaki, Y., Okuda, T., Kawashima, K., Nakata, K., Ruggiero, A.M., Blakely, R.D., Nakatsu, F., Ohno, H.
- Journal Title
  
  Eur.J.Neurosci. 27
  
  Pages: 3109-3117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500340
[Presentation] Identification of an endocytic signal of the vesicular GABA transporter2013
- Author(s)
  Okuda T
- Organizer
  第36回分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25430074
[Presentation] Substrate-induced internalization A novel screen for endocytic motifs of vesicular neurotransmitter transporters2012
- Author(s)
  小山沙織、美濃田茜、神保美紗子、三澤日出巳、奥田隆志
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-23790097
[Presentation] A novel screen for endocytic motifs of vesicular neurotransmitter transporters2012
- Author(s)
  Koyama S, Minoda A, Jimbo M, Misawa H, Okuda T
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23790097
[Presentation] シナプス小胞トランスポーターの細胞内移行モチーフの探2011
- Author(s)
  神保美紗子、三澤日出巳、奥田隆志
- Organizer
  第124回日本薬理学会関東部会
- Place of Presentation
  東京
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-23790097
[Presentation] シナプス小胞トランスポーターの細胞内移行シグナル配列の探索2011
- Author(s)
  神保美紗子、三澤日出巳、奥田隆志
- Organizer
  第124回日本薬理学会関東部会
- Place of Presentation
  東京大学
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-21790091
[Presentation] シナプス小胞トランスポーターの細胞内移行モチーフの探索2011
- Author(s)
  神保美紗子、三澤日出巳、奥田隆志
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(中止)
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21790091
[Presentation] シナプス小胞トランスポーターの細胞内移行シグナル配列の探索2011
- Author(s)
  神保美紗子、三澤日出巳、奥田隆志
- Organizer
  第124回日本薬理学会関東部会
- Place of Presentation
  東京大学
- Data Source
  KAKENHI-PROJECT-23790097
[Presentation] シナプス小胞トランスポーターの細胞内移行モチーフの探索2011
- Author(s)
  神保美紗子、三澤日出巳、奥田隆志
- Organizer
  第84回日本薬理学会年会(震災により中止)
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21790091
[Presentation] SLC5トランスポーターのオリゴマー形成におけるグリシンモチーフの役割2010
- Author(s)
  矢嶋浩平、中田光、奥田隆志、三澤日出巳
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21790091
[Presentation] テトラヒドロピリミジン系薬の新たな中枢神経作用点の同定2010
- Author(s)
  小西麻未、野村有希、奥田隆志、三澤日出巳
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21790091
[Presentation] 高親和性コリントランスポーターの細胞内移行2009
- Author(s)
  奥田隆志, 他
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜市
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-20500340
[Presentation] テトラヒドロピリミジン系薬の新たな中枢神経作用点の同定2009
- Author(s)
  野村有希、小西麻未、奥田隆志、三澤日出巳
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2009
- Place of Presentation
  慶應義塾大学
- Year and Date
  2009-08-24
- Data Source
  KAKENHI-PROJECT-21790091
[Presentation] 小胞神経伝達物質トランスポーターのエンドサイトーシス・局在の分子機構
- Author(s)
  奥田隆志
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-20
- Invited
- Data Source
  KAKENHI-PROJECT-25430074

1. MISAWA Hidemi (80219617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Okuda Takashi 奥田 隆志

OKUDA Takashi 奥田 隆志

奥田 隆志 オクダ タカシ

Research Projects

Research Products

Co-Researchers

Regulatory mechanisms for endocytosis of presynaptic moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A novel cholinergic enhancer and its mechanism of actionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of a novel mechanism of cholinergic activation for cognitive impairment treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel drugs for improving cognitive impairment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

高親和性コリントランスポーターの機能調節Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

高親和性コリン取り込みによるアセチルコリン合成制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 神経変性疾患と創薬、新しい薬学事典2012

Author(s)

Publisher

Data Source

[Book] コリン作動性神経機能素子の制御機構、基礎老化研究36 (3)2012

Author(s)

Data Source

[Book] 高親和性コリントランスポーターの局在と機能、Clinical Neuroscience 302012

Author(s)

Data Source

[Journal Article] Osteopontin is an alpha motor neuron marker in the mouse spinal cord2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transmembrane topology and oligomeric structure of the high-affinity choline transporter2012

Author(s)

Journal Title

Data Source

[Journal Article] Transmembrane topology and oligomeric structure of the high-affinity choline transporter.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Osteopontin is an alpha motor neuron marker in the mouse spinal cord.2012

Author(s)

Journal Title

Data Source

[Journal Article] Substrate-induced internalization of the high-affinity choline transporter2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Substrate-induced internalization of the high-affinity choline transporter2011

Author(s)

Journal Title

Data Source

[Journal Article] Expression of SLURP-1, an endogenous alpha7 nicotinic acetylcholine receptor allosteric ligand, in murine bronchial epithelial cells.2009

Okuda Takashi 奥田隆志

OKUDA Takashi 奥田隆志

奥田隆志オクダタカシ