KAIDZU Sachiko 海津幸子

… Alternative Names

海津幸子カイヅサチコ

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Researcher Number	00325052
Other IDs
Affiliation (Current)	2025: 島根大学, 学術研究院医学・看護学系, 講師
Affiliation (based on the past Project Information) *help	2025: 島根大学, 学術研究院医学・看護学系, 助教 2018 – 2023: 島根大学, 学術研究院医学・看護学系, 助教 2007 – 2017: Shimane University, School of Medicine, Assistant Professor 2006: 島根大学, 医学部, 助手 2003 – 2004: Shimane University School of Medicine, Instructor, 医学部, 助手 2002: 島根医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Ophthalmology / Basic Section 56060:Ophthalmology-related Except Principal Investigator Ophthalmology / Basic Section 56060:Ophthalmology-related / Ophthalmology
Keywords	Principal Investigator 網膜血液関門 / 酸化ストレス / 網膜光障害 / プロテオミクス / 抗酸化酵素 / レーザーマイクロダイセクション / 網膜光傷害 / 眼組織学 / アクアポリン / タイトジャンクション … More / ホメオスタシス / 網膜 / 網膜色素上皮細胞 / 免疫組織化学 / 透過型電子顕微鏡 / 視細胞 / アクアポリン-1 … More Except Principal Investigator 酸化ストレス / ルテイン / 緑内障 / hydroxyoctadecadienoic acid(HODE) / 8-iso-prostaglandin F2α / 抗酸化酵素 / PCR / GPX / 黄斑色素 / 加齢黄斑変性 / 網膜光障害 / SHR / ラット / 眼圧 / 高血圧 / 網膜 / チオール基 / ポリフェノール / 活性酸素 / α-Tocopherol transfer protein (α-TTP) (6) / α-Tocotrienol / α-Tocopherol / hydroxyoctadecadienoic acid / α-Toc輸送蛋白(α-TTP) / α,β,γ-トコトリエノール(Toc-3) / α,β,γ-トコフェロール(Toc) / hydroxyoctadecadienoic acid (HODE) / Apoptosis / Photoreceptor / Retinal Pigment Epithelial Cells / Light damage / TEM / 8OHdG / グルタチオンペルオキシダーゼ / 80HdG / アポトーシス / 視細胞 / 網膜色素上皮細胞 / 電子顕微鏡 / 網膜光傷害 / 80hdG / 脂質酸化マーカー / HODE / 脂質過酸化 / 一重項酸素 / 抗酸化力 / 抗酸化 / MUTHY / OGG１ / MTH1 / MUTYH / OGG1 Less

長波長可視光照射は視機能に正の効果をもたらすか：ラットモデルでの検証Principal Investigator
- Principal Investigator
  
  海津幸子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Shimane University
高血圧自然発症ラットは緑内障モデルとして有用か？
- Principal Investigator
  
  谷戸正樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Shimane University
Studies on how lutein administration enhances antioxidant capacity by increasing reduced thiols
- Principal Investigator
  
  OHIRA Akihiro
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Nagasaki University
Assessment of oxidative stress in samples from glaucoma patients
- Principal Investigator
  
  TANITO MASAKI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Shimane University
Clinical and basic examination of the macula pigment for the macula function
- Principal Investigator
  
  Koyama Yasurou
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Shimane University
Inspection of a change and the lutein effect in the living body of singlet oxygen derived from the light exposure using the new lipid oxidation marker
- Principal Investigator
  
  Ohira Akihiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Shimane University
Study of Pathological Mechanism in Light Induced Retinal Damage using DNA Base Excision Repair Gene Knockout Mice
- Principal Investigator
  
  OHIRA Akihiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Shimane University
Localization and quantitative analysis of retinal protein by lasermicrodissectionPrincipal Investigator
- Principal Investigator
  
  KAIDZU Sachiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Shimane University
網膜内のホメオスタシス維持における網膜血液関門とアクアポリンの相互作用Principal Investigator
- Principal Investigator
  
  海津幸子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Shimane University
The development of new retinal oxidative stress market and the effects of vitamin E intensive care against retinal light damage
- Principal Investigator
  
  OHIRA Akihiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Shimane University
視細胞におけるアクアポリン-1の発現と機能に関する研究Principal Investigator
- Principal Investigator
  
  海津幸子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Shimane University
  Shimane Medical University
Study on Molecular Mechanism and Therapy of Light-induce Retinal Damage
- Principal Investigator
  
  OHIRA Akihiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Shimane University School of Medicine

All 2021 2020 2019 2018 2016 2015 2009 2007 2006

All Journal Article Presentation

[Journal Article] Structural and Functional Change in Albino Rat Retina Induced by Various Visible Light Wavelengths.2021
- Author(s)
  Kaidzu S, Okuno T, Tanito M, Ohira A.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23(1) Issue: 1 Pages: 309-309
- DOI
  10.3390/ijms23010309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09448
[Journal Article] Long-term effects of 222 nm ultraviolet radiation C sterilizing lamps on mice susceptible to ultraviolet radiation.2020
- Author(s)
  Yamano N, Kunisada M, Kaidzu S, Sugihara K, Nishiaki-Sawada A, Ohashi H, Yoshioka A, Igarashi T, Ohira A, Tanito M, Nishigori C
- Journal Title
  
  Photochem Photobiol
  
  Volume: 96 Issue: 4 Pages: 853-862
- DOI
  10.1111/php.13269
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09448
[Journal Article] Suppression of Light-Induced Retinal Degeneration by Quercetin via the AP-1 Pathway in Rats.2019
- Author(s)
  Koyama Y, Kaidzu S, Kim YC, Matsuoka Y, Ishihara T, Ohira A, Tanito M
- Journal Title
  
  Antioxidants (Basel)
  
  Volume: 8(4) Issue: 4 Pages: 79-79
- DOI
  10.3390/antiox8040079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09448
[Journal Article] Carteolol hydrochloride reduces visible light-induced retinal damage in vivo and BSO/glutamate-induced oxidative stress in vitro.2019
- Author(s)
  Matsuo M, Kuse Y, Takahashi K, Kuwahara K, Tanito M, Kaidzu S, Shimazawa M, Hara H, Ohira A
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 139(2) Issue: 2 Pages: 84-90
- DOI
  10.1016/j.jphs.2018.11.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09448
[Journal Article] Protective Effect of Highly Polymeric A-Type Proanthocyanidins from Seed Shells of Japanese Horse Chestnut (Aesculus turbinata BLUME) against Light-Induced Oxidative Damage in Rat Retina2018
- Author(s)
  Ishihara T, Kaidzu S, Kimura H, Koyama Y, Matsuoka Y, Ohira A
- Journal Title
  
  Nutrients
  
  Volume: 10(5) Issue: 5 Pages: 593-593
- DOI
  10.3390/nu10050593
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09448
[Journal Article] Association between systemic oxidative stress and visual field damage in open-angle glaucoma.2016
- Author(s)
  Tanito M, Kaidzu S, Takai Y, Ohira A.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 25792-25792
- DOI
  10.1038/srep25792
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10866
[Journal Article] Correlation between Systemic Oxidative Stress and Intraocular Pressure Level2015
- Author(s)
  Masaki Tanito, Sachiko Kaidzu, Yasuyuki Takai, Akihiro Ohira
- Journal Title
  
  PLOS ONE
  
  Volume: 10 Issue: 7 Pages: e0133582-e0133582
- DOI
  10.1371/journal.pone.0133582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10866
[Journal Article] Acceleration of Age-Related Changes in the Retina in a -Tocopherol Transfer Protein Null Mice Fed a Vitamin E-Deficient Diet.2007
- Author(s)
  Masaki, Tanito, Yasukadu, Yoshida, Sachiko, Kaidzu, Zhi-Hua, Chen, Osamu, Cynshi, Kou-ichi, Jishage, Etsuo, Niki, Akihiro, Ohira
- Journal Title
  
  Investigative Ophthalmology & Vision Science 48 (1)
  
  Pages: 396-404
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591921
[Presentation] Correlation between systemic oxidative stresses and intraocular pressure level.2015
- Author(s)
  Tanito M, Kaidzu S, Takai Y, Ohira A
- Organizer
  ARVO 2015 Annual Meeting
- Place of Presentation
  Denver, CO (アメリカ）
- Year and Date
  2015-05-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10866
[Presentation] ラット網膜光傷害の波長特性2009
- Author(s)
  海津幸子
- Organizer
  第10回島根県眼科冬期学術講演会・第27回島根大学眼科同窓会学会
- Place of Presentation
  出雲(島根)
- Year and Date
  2009-02-15
- Data Source
  KAKENHI-PROJECT-20791252
[Presentation] Action Spectrum of Retinal Light Damage in Albino Rats.2009
- Author(s)
  Sachiko Kaidzu
- Organizer
  ARVO
- Place of Presentation
  USA (Fort Lauderdale, FL).
- Data Source
  KAKENHI-PROJECT-20791252
[Presentation] 可視光によるラット網膜障害の波長依存性2009
- Author(s)
  海津幸子
- Organizer
  第113回日本眼科学会総会
- Place of Presentation
  東京(東京)
- Data Source
  KAKENHI-PROJECT-20791252
[Presentation] Acceleration of age-related changes in retinal structure and biochemistry in vitamin E deficient diet-fed α-tocopherol transfer protein null mice2006
- Author(s)
  Masaki, Tanito, Yasukazu, Yoshida, Sachiko, Kaidzu, Etsuo, Niki, Akihiro, Ohira
- Organizer
  XIIth International Symposium on Retinal Degeneration Algentina (San Carlos de Bariloche)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591921

1. OHIRA Akihiro (00169054)

# of Collaborated Projects: 7 results

# of Collaborated Products: 10 results
2. TANITO Masaki (30284037)

# of Collaborated Projects: 6 results

# of Collaborated Products: 5 results
3. KAIDZU Tatsuo (60215283)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. Yoshida YASUKAZU (90358333)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NAKABEPPU Yusaku (30180350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OKUNO Tsutomu (90332395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Koyama Yasurou (60325058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MASUDA Hisashi (80304278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NONOYAMA Shin (30362924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. UMENO Aya (20749098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 和田孝一郎 (90263467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 原英彰 (20381717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. 北岡隆 (80234235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 並河徹 (50180534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAIDZU Sachiko 海津 幸子

海津 幸子 カイヅ サチコ

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長波長可視光照射は視機能に正の効果をもたらすか：ラットモデルでの検証Principal Investigator

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Localization and quantitative analysis of retinal protein by lasermicrodissectionPrincipal Investigator

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網膜内のホメオスタシス維持における網膜血液関門とアクアポリンの相互作用Principal Investigator

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視細胞におけるアクアポリン-1の発現と機能に関する研究Principal Investigator

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[Journal Article] Structural and Functional Change in Albino Rat Retina Induced by Various Visible Light Wavelengths.2021

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Journal Title

DOI

Data Source

[Journal Article] Long-term effects of 222 nm ultraviolet radiation C sterilizing lamps on mice susceptible to ultraviolet radiation.2020

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Journal Title

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Data Source

[Journal Article] Suppression of Light-Induced Retinal Degeneration by Quercetin via the AP-1 Pathway in Rats.2019

KAIDZU Sachiko 海津幸子

海津幸子カイヅサチコ