Sakamoto Naoaki 坂本尚昭

… Alternative Names

SAKAMOTO Naoaki 坂本尚昭

坂本尚昭サカモトナオアキ

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Researcher Number	00332338
Other IDs
Affiliation (Current)	2025: 広島大学, 統合生命科学研究科(理), 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 広島大学, 統合生命科学研究科(理), 准教授 2017 – 2018: 広島大学, 理学研究科, 准教授 2016: 広島大学, 大学院理学研究科, 准教授 2013 – 2015: 広島大学, 理学(系)研究科(研究院), 准教授 2007 – 2011: Hiroshima University, Graduate School of Science, Associate Professor … More 2006: 広島大学, 大学院理学研究科, 助教授 2005: 広島大学, 大学院・理学研究科, 助教授 2002: 理研, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 43050:Genome biology-related / Genome biology / Genetics/Genome dynamics / Neurochemistry/Neuropharmacology Except Principal Investigator Developmental biology / Basic Section 42020:Veterinary medical science-related / Basic Section 43050:Genome biology-related / Basic Section 43040:Biophysics-related / System genome science
Keywords	Principal Investigator インスレーター / ゲノム / CRISPR-Cas9 / ゲノム編集 / 棘皮動物 / 発生 / 細胞核 / ライブイメージング / 核構造 / HP1 … More / Nucleolin / CenpA / 初期型ヒストン遺伝子 / ポリケチド合成酵素 / 核内構造 / ウニ / エンハンサー遮断活性 / ヌクレオソーム / 反復配列 / 非コードDNA / DNA構造 / DNA 構造 / クロマチン … More Except Principal Investigator イエネコ / ゲノム編集 / 発現制御 / ゲノム / 遺伝子 / 発生・分化 / NGS解析 / 疾患 / White locus / 数理モデル / ライブ観察 / 染色体動態 / DNA二本鎖切断修復 / 核小体 / X染色体対合形成 / CTCF / 核スペックル / ウニ / 遺伝子制御 / 核内構造体 / エピゲノム / ゲノム構造・動態 / 揺らぎ / エンハンサー遮断活性 / 弾性 / ねじれ / インスレーター / DNA / バイオテクノロジー / genome / regulation of expression / development / gene / 転写調節因子 / 発生分化 / ゆらぎ / 発生制御 Less

Comprehensive exploration of the function of the domestic cat white gene and its influence on diseases using molecular cell biology and mathematics
- Principal Investigator
  
  粟津暁紀
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Hiroshima University
Insulator-mediated genome organization and evolution in echinoderm.Principal Investigator
- Principal Investigator
  
  坂本尚昭
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Hiroshima University
Mathematical study of transcriptional control by nuclear structures with non-coding DNA
- Principal Investigator
  
  Awazu Akinori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Hiroshima University
Analysis of insulator function of non-coding DNA using genome editingPrincipal Investigator
- Principal Investigator
  
  Naoaki Sakamoto
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Hiroshima University
Verification of Elastic Regulated Insulator Function by Measuring the Torsional Response of Single DNA Molecule
- Principal Investigator
  
  Murayama Yoshihiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Tokyo University of Agriculture and Technology
Imaging analysis for nuclear dynamics in structural change of nuclei in early embryo and differentiation.Principal Investigator
- Principal Investigator
  
  Sakamoto Naoaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genome biology
- Research Institution
  Hiroshima University
Development of a novel genome editing-mediated gene knock-in system
- Principal Investigator
  
  Yamamoto Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  System genome science
- Research Institution
  Hiroshima University
Physical property of non-coding DNA that is responsible for proper expression of genomic functionPrincipal Investigator
- Principal Investigator
  
  Sakamoto Naoaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genome biology
- Research Institution
  Hiroshima University
Quantitative analysis of cell-cell interaction responsible for the robustness of development
- Principal Investigator
  
  YAMAMOTO Takashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Hiroshima University
Study of molecular mechanism of Ars insulator functionPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Naoaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Hiroshima University
Studies on the gene network responsible for the specific gene expression during development
- Principal Investigator
  
  YAMAMOTO Takashi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Hiroshima University
ポリグルタミン病モデル系のトランスクリプトーム解析Principal Investigator
- Principal Investigator
  
  坂本尚昭
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The Institute of Physical and Chemical Research

[Book] Shall We 遺伝学2009
- Author(s)
  坂本尚昭
- Total Pages
  182
- Publisher
  講談社サイエンティフィック
- Data Source
  KAKENHI-PROJECT-21570226
[Book] Shall We遺伝学2009
- Author(s)
  坂本尚昭
- Total Pages
  182
- Publisher
  講談社サイエンティフィック
- Data Source
  KAKENHI-PROJECT-21570226
[Book] DNA Structure, Chromatin and Gene Expression2006
- Author(s)
  Sakamoto N. et al.
- Total Pages
  252
- Publisher
  Transworld Research Network, India
- Data Source
  KAKENHI-PROJECT-17570179
[Book] Gene Expression and Chromatin2006
- Author(s)
  Sakamoto, N.
- Publisher
  Involvement of nuclear matrix and chromatin loop formation in the functions of insulators
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570179
[Journal Article] Possibilities of skin coat color‐dependent risks and risk factors of squamous cell carcinoma and deafness of domestic cats inferred via RNA‐seq data2023
- Author(s)
  Awazu Akinori、Takemoto Daigo、Watanabe Kaichi、Sakamoto Naoaki
- Journal Title
  
  Genes to Cells
  
  Volume: 28 Issue: 12 Pages: 893-905
- DOI
  10.1111/gtc.13076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18234, KAKENHI-PROJECT-21K06124
[Journal Article] The crucial role of CTCF in mitotic progression during early development of sea urchin2023
- Author(s)
  Watanabe Kaichi、Fujita Megumi、Okamoto Kazuko、Yoshioka Hajime、Moriwaki Miki、Tagashira Hideki、Awazu Akinori、Yamamoto Takashi、Sakamoto Naoaki
- Journal Title
  
  Development, Growth and Differentiation
  
  Volume: 65 Issue: 7 Pages: 395-407
- DOI
  10.1111/dgd.12875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18234, KAKENHI-PROJECT-21K06124
[Journal Article] Partial exogastrulation due to apical-basal polarity of F‐actin distribution disruption in sea urchin embryo by omeprazole2022
- Author(s)
  Watanabe Kaichi、Yasui Yuhei、Kurose Yuta、Fujii Masashi、Yamamoto Takashi、Sakamoto Naoaki、Awazu Akinori
- Journal Title
  
  Genes to Cells
  
  Volume: - Issue: 6 Pages: 1-17
- DOI
  10.1111/gtc.12934
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03223, KAKENHI-PROJECT-21K06124, KAKENHI-PROJECT-21K18234, KAKENHI-PROJECT-19K20382, KAKENHI-PROJECT-20K06602
[Journal Article] CRISPR-Cas9 editing of non-coding genomic loci as a means of controlling gene expression in the sea urchin.2021
- Author(s)
  Pieplow A, Dastaw M, Sakuma T, Sakamoto N, Yamamoto T, Yajima M, Oulhen N, Wessel GM
- Journal Title
  
  Developmental Biology
  
  Volume: 472 Pages: 85-97
- DOI
  10.1016/j.ydbio.2021.01.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06602, KAKENHI-PROJECT-18K06149, KAKENHI-PROJECT-19K16111
[Journal Article] Recycling endosomes associate with Golgi stacks in sea urchin embryos.2020
- Author(s)
  Fujii S, Tago T, Sakamoto N, Yamamoto T, Satoh T, Satoh AK
- Journal Title
  
  Communicative & Integrative Biology
  
  Volume: 13(1) Issue: 1 Pages: 59-62
- DOI
  10.1080/19420889.2020.1761069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06602, KAKENHI-PROJECT-18K06149, KAKENHI-PROJECT-19K06663
[Journal Article] Insulator Activities of Nucleosome-Excluding DNA Sequences without Bound Chromatin Looping Proteins2019
- Author(s)
  Matsushima Yuki、Sakamoto Naoaki、Awazu Akinori
- Journal Title
  
  The Journal of Physical Chemistry B
  
  Volume: 123 Issue: 5 Pages: 1035-1043
- DOI
  10.1021/acs.jpcb.8b10518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0024, KAKENHI-PROJECT-17K05614, KAKENHI-PROJECT-17K07241, KAKENHI-PROJECT-18K06149
[Journal Article] Establishment of knockout adult sea urchins by using a CRISPR‐Cas9 system2019
- Author(s)
  Daming Liu, Akinori Awazu, Tetsushi Sakuma, Takashi Yamamoto, Naoaki Sakamoto
- Journal Title
  
  Development Growth and Regeneration
  
  Volume: 61 Issue: 6 Pages: 378-388
- DOI
  10.1111/dgd.12624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0024, KAKENHI-PROJECT-19K16111, KAKENHI-PROJECT-16H04035, KAKENHI-PROJECT-17K05614, KAKENHI-PROJECT-17K07241
[Journal Article] Biased genome editing using the local accumulation of DSB repair molecules system.2018
- Author(s)
  Nakade S, Mochida K, Kunii A, Nakamae K, Aida T, Tanaka K, Sakamoto N, Sakuma T, Yamamoto T
- Journal Title
  
  Nature Communications
  
  Volume: 9(1) Issue: 1 Pages: 3270-3270
- DOI
  10.1038/s41467-018-05773-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07241, KAKENHI-PROJECT-18K19494, KAKENHI-PROJECT-17H01409, KAKENHI-PROJECT-17H02216, KAKENHI-PROJECT-16K07085, KAKENHI-PROJECT-17K15045
[Journal Article] Dynamic changes in the interchromosomal interaction of early histone gene loci during development of sea urchin2017
- Author(s)
  Matsushita Masaya、Ochiai Hiroshi、Suzuki Ken-ichi T.、Hayashi Sayaka、Yamamoto Takashi、Awazu Akinori、Sakamoto Naoaki
- Journal Title
  
  Journal of Cell Science
  
  Volume: 130 Issue: 24 Pages: 4097-4107
- DOI
  10.1242/jcs.206862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0024, KAKENHI-PROJECT-17K05614, KAKENHI-PROJECT-17K07241
[Journal Article] Simple Elastic Network Models for Exhaustive Analysis of Long Double-Stranded DNA Dynamics with Sequence Geometry Dependence2015
- Author(s)
  Shuhei Isami, Naoaki Sakamoto, Hiraku Nishimori, and Akinori Awazu
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 12 Pages: 143760-143760
- DOI
  10.1371/journal.pone.0143760
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26610117, KAKENHI-PUBLICLY-26120525, KAKENHI-PROJECT-25430169
[Journal Article] Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas92014
- Author(s)
  S. Nakade, T. Tsubota, Y. Sakane, S. Kume, N. Sakamoto, M. Obara, T. Daimon, H. Sezutsu, T. Yamamoto, T. Sakuma and K. T. Suzuki
- Journal Title
  
  Nat Commun
  
  Volume: 5 Issue: 1 Pages: 5560-5560
- DOI
  10.1038/ncomms6560
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22124001, KAKENHI-PROJECT-23688008, KAKENHI-PUBLICLY-25124708, KAKENHI-PROJECT-25292202, KAKENHI-PROJECT-25890014, KAKENHI-PROJECT-26290070
[Journal Article] Nucleosome exclusion from the interspecies conserved central AT-rich region of the Arsinsulater2012
- Author(s)
  Takagi H, Inai Watanabe SI, Tatemoto S, Yajima M, Akasaka K, Yamamoto T, SakamotoN
- Journal Title
  
  J. Biochem
  
  Volume: 151(1) Pages: 78-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570226
[Journal Article] HpSumf1 is involved in the activation of sulafatases responsible for regulation of skeletogenesisduring sea urchin development2011
- Author(s)
  Sakuma T, Ohnishi K, Fujita K, Ochia H, Sakamoto N, Yamamoto T.
- Journal Title
  
  Development Genes and Evolution
  
  Volume: 221(3) Pages: 157-166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570226
[Journal Article] Dicer is required for the normalde velopment of sea urchin2010
- Author(s)
  Okamitsu Y, Yamamoto T, Fujii T, Ochiai H, Sakamoto N
- Journal Title
  
  Hemicentrotus pulcherrimus. Zoological Science
  
  Volume: 27 Pages: 477-486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570226
[Journal Article] Targeted mutagenesis in the sea urchin embryo usingzinc-finger nucleases2010
- Author(s)
  Ochiai H, Fujita K, Suzuki K, Nishikawa M, Shibata T, Sakamoto N, Yamamoto T.
- Journal Title
  
  Genes to Cells
  
  Volume: 15 Pages: 875-885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570226
[Journal Article] Implication of HpEts in gene regulatory networks responsible for specification of seaurchin sleletogenic primary me senchyme cells2010
- Author(s)
  Yajima M, Umeda R, Fuchikami T, Kataoka M, Sakamoto N, Yamamoto T, Akasaka K.
- Journal Title
  
  Zoological Science
  
  Volume: 27 Pages: 638-646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570226
[Journal Article] Mammalian arylsulfatase A functions as a novel component of the extracellular matrix2010
- Author(s)
  Fujita K, Teramura N, Hattori S, Irie S, Mitsunaga-Nakatsubo K, Akimoto Y, SakamotoN, Yamamoto T, Akasaka K.
- Journal Title
  
  Connective Tissue Research
  
  Volume: 51 Pages: 388-396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570226
[Journal Article] HpSulf, a heparin sulfate 6-O-endosulfatase, is involved in the regulation of VEGF signaling during seaurchin development2009
- Author(s)
  Fujita K, Takechi E, Sakamoto N, SumiyoshiN, Izumi S, Miyamoto T, Matsuura S, Tsurugaya T, Akasaka K, Yamamoto T.
- Journal Title
  
  Mechanisms of Development
  
  Volume: 127 Pages: 235-245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570226
[Journal Article] Role of the nanos homolog during sea urchin development2009
- Author(s)
  Fujii T, Sakamoto N, Ochiai H, Fujita K, Okamitsu Y, Sumiyoshi N, Minokawa T, Yamamoto T.
- Journal Title
  
  Developmental Dynamics
  
  Volume: 238 Pages: 2511-2521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570226
[Journal Article] Suppressor of hairless(Su(H)) is required for foregut development in the sea urchin embryo2009
- Author(s)
  Karasawa K, Sakamoto N, Fujita K, Ochiai H, Fujii T, Akasaka K, Yamamoto T.
- Journal Title
  
  Zoological Science
  
  Volume: 26 Pages: 686-690
- NAID
  40016807049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570226
[Journal Article] Analysis of cis-regulatory elements controlling spatio-temporal expression of T-brain gene in sea urchin, Hemicentrotus pulcherrimus.2008
- Author(s)
  Ochiai, H., Sakamoto, N., Momiyama, A., Akasaka, K., and Yamamoto T.
- Journal Title
  
  Mechamism of Development Vol. 125
  
  Pages: 2-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770005
[Journal Article] The Ars insulator facilitates I-SceI meganuclease-mediated transgenesis in the sea urchin embryo.2008
- Author(s)
  Ochiai, H., Sakamoto, N., Suzuki, K., Akasaka, K., and Yamamoto T.
- Journal Title
  
  Developmental Dynamics Vol. 237
  
  Pages: 2475-2482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770005
[Journal Article] DNA variations within the sea urchin Otx gene enhancer.2007
- Author(s)
  Yamamoto, T., Kawamoto, R., Fujii, T., Sakamoto, N., and Shibata T.
- Journal Title
  
  FEBS Letters Vol. 581
  
  Pages: 5234-5240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770005
[Patent] 新規DNA結合ドメインおよびそれを含む新規DNA切断酵素2011
- Inventor(s)
  山本卓・坂本尚昭・佐久間哲史・野地澄晴
- Industrial Property Rights Holder
  広島大学
- Industrial Property Number
  2011-242250
- Filing Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21570226
[Presentation] ウニのCTCFは初期発生において分裂期の進行に必須である2023
- Author(s)
  坂本尚昭, 渡辺開智, 藤田恵, 岡本和子, 吉岡一, 森脇三貴, 田頭英樹, 粟津暁紀, 山本卓,
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06124
[Presentation] 培養細胞を用いた白いネコ特有のゲノムと疾患の解析2023
- Author(s)
  渡邊開智, 竹本大悟, 坂本尚昭, 粟津暁紀
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06124
[Presentation] ウニFLVCR遺伝子機能解析とFLVCR遺伝子ノックアウト胚の表現型観察2023
- Author(s)
  竹本大悟, 三澤祐太朗, 渡辺開智, 坂本尚昭, 粟津暁紀
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06124
[Presentation] Exogastrulation due to cytoskeletal polarity distribution in sea urchin embryo2022
- Author(s)
  Kaichi Watanabe, Yuhei Yasui, Yuta Kurose, Naoaki Sakamoto, Akinori Awazu
- Organizer
  The 60th Annual Meeting of the Biophysical Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06124
[Presentation] ムラサキウニにおけるCRISPR/Cas9システムを用いたゲノム編集2022
- Author(s)
  坂本尚昭, 渡辺開智, 粟津暁紀, 山本卓
- Organizer
  日本ゲノム編集学第7回大会
- Data Source
  KAKENHI-PROJECT-20K06602
[Presentation] ウニ胚形態形成の細胞骨格観察に基づくモデル化2021
- Author(s)
  渡辺開智, 安井優平, 黒瀬友太, 坂本尚昭, 粟津暁紀
- Organizer
  日本動物学会第92回大会
- Data Source
  KAKENHI-PROJECT-20K06602
[Presentation] エンハンサー・プロモーター間のDNA特性による転写活性化への影響2021
- Author(s)
  中川春風, 高木春奈, 立本小百合, 粟津暁紀, 山本卓, 坂本尚昭
- Organizer
  日本動物学会第92回大会
- Data Source
  KAKENHI-PROJECT-20K06602
[Presentation] MaChIAto：CRISPRによるゲノム編集結果と標的のゲノム特性との関連性プロファイリングツール2020
- Author(s)
  中前和恭、武永充正、中出翔太、名塚一郎、粟津暁紀、坂本尚昭、佐久間哲史、山本卓
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06602
[Presentation] ウニ胚形態形成の細胞骨格観察に基づくモデル化2020
- Author(s)
  渡辺開智, 黒瀬友太, 安井優平, 坂本尚昭, 粟津暁紀
- Organizer
  日本動物学会第91回大会
- Data Source
  KAKENHI-PROJECT-20K06602
[Presentation] ウニの発生初期における核内染色体構造の動的および細胞特異的変化2020
- Author(s)
  安井優平, 杉山文香, 坂本尚昭, 粟津暁紀
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20K06602
[Presentation] ウニ胚形態形成の細胞骨格観察に基づくモデル化2020
- Author(s)
  渡辺開智, 黒瀬友太, 安井優平, 坂本尚昭, 粟津暁紀
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20K06602
[Presentation] ウニの発生初期における核内染色体構造の動的および細胞特異的変化2020
- Author(s)
  安井優平, 杉山文香, 坂本尚昭, 粟津暁紀
- Organizer
  日本動物学会第91回大会
- Data Source
  KAKENHI-PROJECT-20K06602
[Presentation] ウニ初期胚の核及び核内動態の蛍光イメージング観察・解析2020
- Author(s)
  今田実子, 杉山文香, 林紗弥香, 渡邊開智, 安井優平, 坂本尚昭, 粟津暁紀
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20K06602
[Presentation] Extended analysis of amplicon sequencing data with MaChIAto for Prime Editing2020
- Author(s)
  Nakamae K, Takenaga M, Nakade S, Nazuka I, Awazu A, Sakamoto N, Sakuma T, Yamamoto T
- Organizer
  CSHL meeting - Genome Engineering: CRISPR Frontiers
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06602
[Presentation] MaChIAto: detailed profiling tool for various genomic features affecting the efficacy of gene knockout, homology-based knock-in, and Prime Editing2020
- Author(s)
  Sakura T, Nakamae K, Takenaga M, Nakade S, Mitsuhashi T, Nazuka I, Awazu A, Sakamoto N, Yamamoto T
- Organizer
  CRISPR and Beyond
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06602
[Presentation] ArsInsC配列及びDNA反復配列の物理的特性・機能性解析2020
- Author(s)
  小田竜平, 藤井雅史, 坂本尚昭, 粟津暁紀
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20K06602
[Presentation] Establishment of knockout adult sea urchin by using CRISPR-Cas9 system2019
- Author(s)
  Liu D, Awazu A, Sakuma T, Yamamoto T, Sakamoto N
- Organizer
  日本ゲノム編集学会第4 回大会
- Data Source
  KAKENHI-PROJECT-17K07241
[Presentation] ヌクレオソーム排他的領域のインスレーター機能の解析2018
- Author(s)
  松島佑樹, 西森拓, 坂本尚昭, 粟津暁紀
- Organizer
  第56会生物物理学会
- Data Source
  KAKENHI-PROJECT-18K06149
[Presentation] Dynamic changes in the interchromosomal interaction of early histone gene loci during development of sea urchin2018
- Author(s)
  松下将也, 落合博, 鈴木賢一, 林紗弥香, 杉山文香, 山本卓, 粟津暁紀, 坂本尚昭
- Organizer
  第56会生物物理学会
- Data Source
  KAKENHI-PROJECT-18K06149
[Presentation] CRISPR/Cas9システムを用いたバフンウニにおけるゲノム編集2018
- Author(s)
  Liu Daming, 粟津暁紀, 佐久間哲史, 山本卓, 坂本尚昭
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K07241
[Presentation] バフンウニ初期発生における初期型ヒストン遺伝子動態の解析2016
- Author(s)
  松下将也, 落合博, 山本卓, 粟津暁紀, 坂本尚昭
- Organizer
  第33回染色体ワークショップ・第14回核ダイナミクス研究会合同開催
- Place of Presentation
  松島一の坊（宮城）
- Year and Date
  2016-01-12
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] 粗視化モデルを用いたDNAの塩基配列の特性と塩基配列に依存した構造・運動・機能・の関係の解析2016
- Author(s)
  亀田健, 勇修平, 池谷淳, 西森拓, 坂本尚昭, 粟津暁紀
- Organizer
  第33回染色体ワークショップ・第14回核ダイナミクス研究会合同開催
- Place of Presentation
  松島一の坊（宮城）
- Year and Date
  2016-01-12
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] Simple elastic network models for exhoustive analysis of long double-stranded DNA dynamics with sequence geometry dependence.2016
- Author(s)
  Shuhei Isami, Naoaki Sakamoto, Hiraku Nishimori, Akinori Awazu
- Organizer
  The 7th Taiwan-Japan Joint Workshop for Young Scholar in Applied Mathematics
- Place of Presentation
  National Cheng Kung Univ. (Taiwan)
- Year and Date
  2016-02-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] Arsインスレーターにおける作用メカニズムの解析2016
- Author(s)
  池谷淳, 亀田健, 勇修平, 山本卓, 粟津暁紀, 坂本尚昭
- Organizer
  第33回染色体ワークショップ・第14回核ダイナミクス研究会合同開催
- Place of Presentation
  松島一の坊（宮城）
- Year and Date
  2016-01-12
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] 弾性ネットワークモデルによるDNA配列依存的な力学特性と機能の関係の網羅的解析2016
- Author(s)
  勇修平, 西森拓, 坂本尚昭, 粟津暁紀
- Organizer
  第33回染色体ワークショップ・第14回核ダイナミクス研究会合同開催
- Place of Presentation
  松島一の坊（宮城）
- Year and Date
  2016-01-12
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] 弾性ネットワークモデルを用いたゲノムの動態と機能の解析2016
- Author(s)
  亀田健, 勇修平, 西森拓, 坂本尚昭, 粟津暁紀
- Organizer
  日本物理学会年会
- Place of Presentation
  東北大学
- Year and Date
  2016-03-19
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] Analysis of the relationship among sequences, structures, motions and the functions of DNA by elastic network models.2015
- Author(s)
  Shuhei Isami, Sayuri Tatemoto, Atsushi Ikegaya, Hiraku Nishimori, Naoaki Sakamoto, Akinori Awazu
- Organizer
  日本生物物理学会年会
- Place of Presentation
  金沢大学
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] Simple elastic network models for exhoustive analysis of long double-stranded DNA dynamics with sequence geometry dependence.2015
- Author(s)
  Shuhei Isami, Atsushi Ikegaya, Naoaki Sakamoto, Hiraku Nishimori, Akinori Awazu
- Organizer
  4th International Symposium of the Mathematics on Chromatin Live Dynamics
- Place of Presentation
  JMS Aster PLAZA. (Hiroshima)
- Year and Date
  2015-12-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] バフンウニCTCFホモログ(HpCTCF)のArsインスレーター結合能および機能の解析2011
- Author(s)
  坂本尚昭
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21570226
[Presentation] Arsインスレーター機能の分子メカニズムの解析2007
- Author(s)
  坂本尚昭
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19770005
[Presentation] Ars インスレーター機能の分子メカニズムの解析2007
- Author(s)
  坂本尚昭
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-17570179
[Presentation] Study on the functional mechanism of Ars insulator2007
- Author(s)
  Sakamoto, N
- Organizer
  30st annual meeting for molecular biology society of Japan
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570179
[Presentation] Arsインスレーター機能の分子メカニズムの解析2007
- Author(s)
  坂本尚昭
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-19770005
[Presentation] Arsインスレーター機能の分子メカニズムの解析2007
- Author(s)
  坂本尚昭
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570179
[Presentation] Analysis of dynamic characteristics of Ars-insulator by coarse-grained models
- Author(s)
  Shuhei Isami, Sayuri Tatemoto, Hiraku Nishimori, Naoaki Sakamoto, Akinori Awazu
- Organizer
  第52回日本生物物理学会年会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] 分子動力学法を用いたDNAの塩基配列に依存した力学的特性の考察
- Author(s)
  勇修平, 立本小百合, 西森拓, 坂本尚昭, 粟津暁紀
- Organizer
  日本生物物理学会第6回中国四国支部大会
- Place of Presentation
  とりぎん文化会館（鳥取）
- Year and Date
  2014-05-17 – 2014-05-18
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] DNAの粗視化モデルによるArsインスレーターの運動性と機能性の解析
- Author(s)
  山本佳典, 立本小百合, 坂本尚昭, 粟津暁紀
- Organizer
  第51回日本生物物理学会年会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] 弾性ネットワークモデルによるDNAの配列・構造・運動と機能の関係の考察
- Author(s)
  勇修平, 立本小百合, 池谷淳, 西森拓, 坂本尚昭, 粟津暁紀
- Organizer
  生命動態の分子メカニズムと数理
- Place of Presentation
  京都大（京都）
- Year and Date
  2015-03-16 – 2015-03-17
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] MMEJ-mediated integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9
- Author(s)
  Nakade S, Tsubota T, Sakane Y, Kume S, Sakamoto N, Obara M, Daimon T, Sezutsu H, Yamamoto T, Sakuma T and Suzuki KI
- Organizer
  Keystone Sympsia
- Place of Presentation
  Big Sky, MT, USA
- Year and Date
  2015-01-11 – 2015-01-16
- Data Source
  KAKENHI-PROJECT-26290070
[Presentation] 粗視化モデルを用いたArsインスレーターの力学的特性の考察
- Author(s)
  勇修平, 立本小百合, 西森拓, 坂本尚昭, 粟津暁紀
- Organizer
  日本物理学会2014年秋季大会
- Place of Presentation
  中部大（愛知）
- Year and Date
  2014-09-07 – 2014-09-10
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] DNAの粗視化モデルによるArsインスレーターの力学的特性の考察
- Author(s)
  勇修平, 立本小百合, 池谷淳, 坂本尚昭, 西森拓, 粟津暁紀
- Organizer
  第32回染色体ワークショップ・第13回核ダイナミクス研究会
- Place of Presentation
  安芸グランドホテル（広島）
- Year and Date
  2014-12-15 – 2014-12-17
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] DNAの配列・構造・運動と機能の関係の考察
- Author(s)
  勇修平, 立本小百合, 池谷淳, 西森拓, 坂本尚昭, 粟津暁紀
- Organizer
  日本物理学会第70回年次大会
- Place of Presentation
  早稲田大（東京）
- Year and Date
  2015-03-21 – 2015-03-24
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] DNAの粗視化モデルによるArsインスレーターの運動性と機能性の解析
- Author(s)
  山本佳典, 立本小百合, 西森拓, 坂本尚昭, 粟津暁紀
- Organizer
  日本物理学会 2013年秋季大会
- Place of Presentation
  徳島大学常三島キャンパス
- Data Source
  KAKENHI-PROJECT-25430169
[Presentation] Analysis of dynamic characteristics of Ars-insulator by coarse-grained DNA models
- Author(s)
  Shuhei Isami, Sayuri Tatemoto, Atsushi Ikegaya, Naoaki Sakamoto, Hiraku Nishimori, Akinori Awazu
- Organizer
  The 4D Nucleome 2014
- Place of Presentation
  安芸グランドホテル（広島）
- Year and Date
  2014-12-17 – 2014-12-20
- Data Source
  KAKENHI-PROJECT-25430169

1. Awazu Akinori (00448234)

# of Collaborated Projects: 5 results

# of Collaborated Products: 24 results
2. YAMAMOTO Takashi (90244102)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
3. SHIBATA Tatsuo (10359888)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. AIDA TOMOMI (50540481)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SUZUKI KENICHI (90363043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. Murayama Yoshihiro (60334249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 谷口俊介 (00505331)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 上野勝 (90293597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 下出紗弓 (90772103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KINO Toshiharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 林文夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 西森拓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakamoto Naoaki 坂本 尚昭

SAKAMOTO Naoaki 坂本 尚昭

坂本 尚昭 サカモト ナオアキ

Research Projects

Research Products

Co-Researchers

Comprehensive exploration of the function of the domestic cat white gene and its influence on diseases using molecular cell biology and mathematics

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Insulator-mediated genome organization and evolution in echinoderm.Principal Investigator

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Mathematical study of transcriptional control by nuclear structures with non-coding DNA

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Analysis of insulator function of non-coding DNA using genome editingPrincipal Investigator

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Verification of Elastic Regulated Insulator Function by Measuring the Torsional Response of Single DNA Molecule

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Imaging analysis for nuclear dynamics in structural change of nuclei in early embryo and differentiation.Principal Investigator

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Development of a novel genome editing-mediated gene knock-in system

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Physical property of non-coding DNA that is responsible for proper expression of genomic functionPrincipal Investigator

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Quantitative analysis of cell-cell interaction responsible for the robustness of development

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Study of molecular mechanism of Ars insulator functionPrincipal Investigator

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Studies on the gene network responsible for the specific gene expression during development

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ポリグルタミン病モデル系のトランスクリプトーム解析Principal Investigator

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[Book] Shall We 遺伝学2009

Author(s)

Sakamoto Naoaki 坂本尚昭

SAKAMOTO Naoaki 坂本尚昭

坂本尚昭サカモトナオアキ